Product References
Angiotensin II type 2 receptor agonist attenuates LPS-induced acute lung injury through modulating THP-1-derived macrophage reprogramming.
Naunyn-Schmiedeberg's archives of pharmacology
Chen L,Gong P,Su Y,Meng L,Wang M,Gao W,Liu Q
Mon Jan 01 00:00:00 EST 2024
Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca2+ through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation.
Nutrients
Zheng Q,He Y,Li L,Rui C,Li N,Zhang Y,Ye Y,Zhang Z,Yang X,Tang J,Xu Z
Tue Jan 03 00:00:00 EST 2023
Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.
European journal of pharmacology
Sun Y,Liu X,Wang L,Li L,Quan X,Shi H,Wang T,Mei L,Chen Y,Zhang Y,Li J,Meng R,Wang J,Dai F
Fri May 05 00:00:00 EDT 2023
XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wei XH,Liu WJ,Jiang W,Lan TH,Pan H,Ma MY,You LZ,Shang HC
Mon May 01 00:00:00 EDT 2023
XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wei XH,Liu WJ,Jiang W,Lan TH,Pan H,Ma MY,You LZ,Shang HC
Mon May 01 00:00:00 EDT 2023
Inhibition of angiotensin II type 1 receptor reduces oxidative stress damage to the intestinal barrier in severe acute pancreatitis.
The Kaohsiung journal of medical sciences
Gao ZY,Jiang YJ,Wang J,Li C,Zhang DL
Tue Aug 01 00:00:00 EDT 2023
Inhibition of angiotensin II type 1 receptor reduces oxidative stress damage to the intestinal barrier in severe acute pancreatitis.
The Kaohsiung journal of medical sciences
Gao ZY,Jiang YJ,Wang J,Li C,Zhang DL
Tue Aug 01 00:00:00 EDT 2023
Formaldehyde causes an increase in blood pressure by activating ACE/AT1R axis.
Toxicology
Wang S,Han Q,Wei Z,Wang Y,Deng L,Chen M
Wed Mar 01 00:00:00 EST 2023
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Journal of ethnopharmacology
Fu S,Song X,Tang X,Qian X,Du Z,Hu Y,Xu X,Zhang M
Mon Apr 24 00:00:00 EDT 2023
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+ CAFs in intrahepatic cholangiocarcinoma.
Clinical and translational medicine
Li JH,Wu X,Ni X,Li YX,Xu L,Hao XY,Zhao W,Zhu XX,Yin XY
Wed Mar 01 00:00:00 EST 2023
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+ CAFs in intrahepatic cholangiocarcinoma.
Clinical and translational medicine
Li JH,Wu X,Ni X,Li YX,Xu L,Hao XY,Zhao W,Zhu XX,Yin XY
Wed Mar 01 00:00:00 EST 2023
Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation.
Antioxidants (Basel, Switzerland)
Zhu T,Song J,Gao B,Zhang J,Li Y,Ye Z,Zhao Y,Guo X,Xu F,Li F
Thu Mar 09 00:00:00 EST 2023
Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation.
Antioxidants (Basel, Switzerland)
Zhu T,Song J,Gao B,Zhang J,Li Y,Ye Z,Zhao Y,Guo X,Xu F,Li F
Thu Mar 09 00:00:00 EST 2023
Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation.
Antioxidants (Basel, Switzerland)
Zhu T,Song J,Gao B,Zhang J,Li Y,Ye Z,Zhao Y,Guo X,Xu F,Li F
Thu Mar 09 00:00:00 EST 2023
The effects of angiotensin I-converting enzyme inhibitory peptide VGINYW and the hydrolysate of α-lactalbumin on blood pressure, oxidative stress and gut microbiota of spontaneously hypertensive rats.
Food & function
Xie D,Shen Y,Su E,Du L,Xie J,Wei D
Mon Mar 07 00:00:00 EST 2022
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
BMC molecular and cell biology
Zhu Z,Zhao Z,Chen X,Chu Z,He Y,Tan Y,Zhou J,Tang C
Thu Sep 29 00:00:00 EDT 2022
Extract of Corallodiscus flabellata attenuates renal fibrosis in SAMP8 mice via the Wnt/β-catenin/RAS signaling pathway.
BMC complementary medicine and therapies
Cao B,Zeng M,Si Y,Zhang B,Wang Y,Xu R,Huang Y,Feng W,Zheng X
Mon Feb 28 00:00:00 EST 2022
Exercise Normalized the Hippocampal Renin-Angiotensin System and Restored Spatial Memory Function, Neurogenesis, and Blood-Brain Barrier Permeability in the 2K1C-Hypertensive Mouse.
International journal of molecular sciences
Chang YS,Lin CL,Lee CW,Lin HC,Wu YT,Shih YH
Mon May 16 00:00:00 EDT 2022
Salt-Sensitive Hypertension Induces Osteoclastogenesis and Bone Resorption via Upregulation of Angiotensin II Type 1 Receptor Expression in Osteoblasts.
Frontiers in cell and developmental biology
Pramusita A,Kitaura H,Ohori F,Noguchi T,Marahleh A,Nara Y,Kinjo R,Ma J,Kanou K,Tanaka Y,Mizoguchi I
Sat Jul 16 00:00:00 EDT 2022
Suppression of AGTR1 Induces Cellular Senescence in Hepatocellular Carcinoma Through Inactivating ERK Signaling.
Frontiers in bioengineering and biotechnology
Wang H,Cui Y,Gong H,Xu J,Huang S,Tang A
Tue Aug 02 00:00:00 EDT 2022
Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.
Frontiers in pharmacology
Deng D,Qu Y,Sun L,Jia L,Bu J,Ye M,Chen Z,Geng Y,Zhou S,Fang B
Wed Mar 10 00:00:00 EST 2021
Paternal long-term PM2.5 exposure causes hypertension via increased renal AT1R expression and function in male offspring.
Clinical science (London, England : 1979)
Hu C,Tao Y,Deng Y,Cai Q,Ren H,Yu C,Zheng S,Yang J,Zeng C
Fri Nov 26 00:00:00 EST 2021
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Molecular nutrition & food research
Feng X,Yu T,Zhang Y,Li L,Qu M,Wang J,Dong F,Zhang L,Wang F,Zhang F,Zhou X,Xu Z,Man D
Tue Jun 01 00:00:00 EDT 2021
Parental PM2 .5 exposure changes Th17/Treg cells in offspring, is associated with the elevation of blood pressure.
Environmental toxicology
Pan K,Jiang S,Du X,Zeng X,Zhang J,Song L,Lei L,Zhou J,Kan H,Sun Q,Xie Y,Dong C,Zhao J
Tue Jun 01 00:00:00 EDT 2021
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Aging cell
Dang R,Yang M,Cui C,Wang C,Zhang W,Geng C,Han W,Jiang P
Fri Oct 01 00:00:00 EDT 2021
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Cell research
Fu Y,Huang Y,Yang Z,Chen Y,Zheng J,Mao C,Li Z,Liu Z,Yu B,Li T,Wang M,Xu C,Zhou Y,Zhao G,Jia Y,Guo W,Jia X,Zhang T,Li L,Liu Z,Guo S,Ma M,Zhang H,Liu B,Du J,Wang W,Tang C,Gao P,Xu Q,Wang X,Liu J,Sun J,Kong W
Thu Jul 01 00:00:00 EDT 2021
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Cell research
Fu Y,Huang Y,Yang Z,Chen Y,Zheng J,Mao C,Li Z,Liu Z,Yu B,Li T,Wang M,Xu C,Zhou Y,Zhao G,Jia Y,Guo W,Jia X,Zhang T,Li L,Liu Z,Guo S,Ma M,Zhang H,Liu B,Du J,Wang W,Tang C,Gao P,Xu Q,Wang X,Liu J,Sun J,Kong W
Thu Jul 01 00:00:00 EDT 2021
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Cell research
Fu Y,Huang Y,Yang Z,Chen Y,Zheng J,Mao C,Li Z,Liu Z,Yu B,Li T,Wang M,Xu C,Zhou Y,Zhao G,Jia Y,Guo W,Jia X,Zhang T,Li L,Liu Z,Guo S,Ma M,Zhang H,Liu B,Du J,Wang W,Tang C,Gao P,Xu Q,Wang X,Liu J,Sun J,Kong W
Thu Jul 01 00:00:00 EDT 2021
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Cell research
Fu Y,Huang Y,Yang Z,Chen Y,Zheng J,Mao C,Li Z,Liu Z,Yu B,Li T,Wang M,Xu C,Zhou Y,Zhao G,Jia Y,Guo W,Jia X,Zhang T,Li L,Liu Z,Guo S,Ma M,Zhang H,Liu B,Du J,Wang W,Tang C,Gao P,Xu Q,Wang X,Liu J,Sun J,Kong W
Thu Jul 01 00:00:00 EDT 2021
The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice.
Frontiers in pharmacology
Gao M,Ma Y,Luo J,Li D,Jiang M,Jiang Q,Pi J,Chen R,Chen W,Zhang R,Zheng Y,Cui L
Tue Mar 16 00:00:00 EDT 2021
The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice.
Frontiers in pharmacology
Gao M,Ma Y,Luo J,Li D,Jiang M,Jiang Q,Pi J,Chen R,Chen W,Zhang R,Zheng Y,Cui L
Tue Mar 16 00:00:00 EDT 2021
A potential impact of SARS-CoV-2 on pituitary glands and pituitary neuroendocrine tumors.
Endocrine
Gu WT,Zhou F,Xie WQ,Wang S,Yao H,Liu YT,Gao L,Wu ZB
Sat May 01 00:00:00 EDT 2021
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Hypertension research : official journal of the Japanese Society of Hypertension
Liu C,Li X,Fu J,Chen K,Liao Q,Wang J,Chen C,Luo H,Jose PA,Yang Y,Yang J,Zeng C
Sun Aug 01 00:00:00 EDT 2021
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Hypertension research : official journal of the Japanese Society of Hypertension
Liu C,Li X,Fu J,Chen K,Liao Q,Wang J,Chen C,Luo H,Jose PA,Yang Y,Yang J,Zeng C
Sun Aug 01 00:00:00 EDT 2021
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Hypertension research : official journal of the Japanese Society of Hypertension
Liu C,Li X,Fu J,Chen K,Liao Q,Wang J,Chen C,Luo H,Jose PA,Yang Y,Yang J,Zeng C
Sun Aug 01 00:00:00 EDT 2021
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Hypertension research : official journal of the Japanese Society of Hypertension
Liu C,Li X,Fu J,Chen K,Liao Q,Wang J,Chen C,Luo H,Jose PA,Yang Y,Yang J,Zeng C
Sun Aug 01 00:00:00 EDT 2021
A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.
eLife
Kim GJ,Mo H,Liu H,Wu Z,Chen S,Zheng J,Zhao X,Nucum D,Shortland J,Peng L,Elepano M,Tang B,Olson S,Paras N,Li H,Renslo AR,Arkin MR,Huang B,Lu B,Sirota M,Guo S
Wed Sep 22 00:00:00 EDT 2021
A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.
eLife
Kim GJ,Mo H,Liu H,Wu Z,Chen S,Zheng J,Zhao X,Nucum D,Shortland J,Peng L,Elepano M,Tang B,Olson S,Paras N,Li H,Renslo AR,Arkin MR,Huang B,Lu B,Sirota M,Guo S
Wed Sep 22 00:00:00 EDT 2021
HUANGKUISIWUFANG inhibits pyruvate dehydrogenase to improve glomerular injury in anti-Thy1 nephritis model.
Journal of ethnopharmacology
Lu T,Bian Y,Zhu Y,Guo M,Yang Y,Guo J,Gu C,Duan JA
Sun May 10 00:00:00 EDT 2020
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.
BioMed research international
Chen Q,Yu WY,Zhang HH,Zhang SZ,Fang J,Wu F,Ying HZ,Yu CH
Mon Nov 02 00:00:00 EST 2020
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
The Journal of endocrinology
Su H,Chen X,Zhang Y,Qi L,He Y,Lv J,Zhang Y,Li X,Tang J,Xu Z
Wed Jan 01 00:00:00 EST 2020
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Neural plasticity
Feng P,Wu Z,Liu H,Shen Y,Yao X,Li X,Shen Z
Wed Apr 07 00:00:00 EDT 2021
Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors.
Acta biochimica et biophysica Sinica
Wu J,Chu Y,Jiang Z,Yu Q
Thu Jan 02 00:00:00 EST 2020
Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors.
Acta biochimica et biophysica Sinica
Wu J,Chu Y,Jiang Z,Yu Q
Thu Jan 02 00:00:00 EST 2020
Ambient fine particulate matter induced the elevation of blood pressure through ACE2/Ang(1-7) pathway: The evidence from urine metabolites.
Ecotoxicology and environmental safety
Du X,Zeng X,Zhang J,Pan K,Song L,Zhou J,Zhou L,Xie Y,Sun Q,Ge W,Chen R,Zhao J,Kan H
Thu Oct 15 00:00:00 EDT 2020
Aldosterone from endometrial glands is benefit for human decidualization.
Cell death & disease
Li SY,Song Z,Yan YP,Li B,Song MJ,Liu YF,Yang ZS,Li MY,Liu AX,Quan S,Yang ZM
Thu Aug 13 00:00:00 EDT 2020
Aldosterone from endometrial glands is benefit for human decidualization.
Cell death & disease
Li SY,Song Z,Yan YP,Li B,Song MJ,Liu YF,Yang ZS,Li MY,Liu AX,Quan S,Yang ZM
Thu Aug 13 00:00:00 EDT 2020
Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function.
Journal of cellular and molecular medicine
Wen J,Zhang L,Wang J,Wang J,Wang L,Wang R,Li R,Liu H,Wei S,Li H,Zou W,Zhao Y
Wed Apr 01 00:00:00 EDT 2020
Puerarin Reduces Blood Pressure in Spontaneously Hypertensive Rats by Targeting eNOS.
The American journal of Chinese medicine
Shi W,Yuan R,Chen X,Xin Q,Wang Y,Shang X,Cong W,Chen K
Fri Mar 15 00:00:00 EDT 2019
Puerarin Reduces Blood Pressure in Spontaneously Hypertensive Rats by Targeting eNOS.
The American journal of Chinese medicine
Shi W,Yuan R,Chen X,Xin Q,Wang Y,Shang X,Cong W,Chen K
Fri Mar 15 00:00:00 EDT 2019
Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension.
Journal of geriatric cardiology : JGC
Shi L,Liu XY,Huang ZG,Ma ZY,Xi Y,Wang LY,Sun NL
Fri Nov 01 00:00:00 EDT 2019
Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system.
Redox biology
Cui C,Xu P,Li G,Qiao Y,Han W,Geng C,Liao D,Yang M,Chen D,Jiang P
Sun Sep 01 00:00:00 EDT 2019
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Journal of cellular physiology
Bian X,Bai Y,Su X,Zhao G,Sun G,Li D
Sun Dec 01 00:00:00 EST 2019
Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice.
Ecotoxicology and environmental safety
Xie X,Deng T,Duan J,Ding S,Yuan J,Chen M
Sat Jun 15 00:00:00 EDT 2019
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles.
Biomaterials
Zhu Y,Wen L,Shao S,Tan Y,Meng T,Yang X,Liu Y,Liu X,Yuan H,Hu F
Sun Apr 01 00:00:00 EDT 2018
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles.
Biomaterials
Zhu Y,Wen L,Shao S,Tan Y,Meng T,Yang X,Liu Y,Liu X,Yuan H,Hu F
Sun Apr 01 00:00:00 EDT 2018
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Oxidative medicine and cellular longevity
Qin B,Wang Q,Lu Y,Li C,Hu H,Zhang J,Wang Y,Zhu J,Zhu Y,Xun Y,Wang S
Thu Oct 11 00:00:00 EDT 2018
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Oxidative medicine and cellular longevity
Qin B,Wang Q,Lu Y,Li C,Hu H,Zhang J,Wang Y,Zhu J,Zhu Y,Xun Y,Wang S
Thu Oct 11 00:00:00 EDT 2018
The Kidney Injury Induced by Short-Term PM2.5 Exposure and the Prophylactic Treatment of Essential Oils in BALB/c Mice.
Oxidative medicine and cellular longevity
Zhang Y,Li Q,Fang M,Ma Y,Liu N,Yan X,Zhou J,Li F
Tue Dec 11 00:00:00 EST 2018
The Kidney Injury Induced by Short-Term PM2.5 Exposure and the Prophylactic Treatment of Essential Oils in BALB/c Mice.
Oxidative medicine and cellular longevity
Zhang Y,Li Q,Fang M,Ma Y,Liu N,Yan X,Zhou J,Li F
Tue Dec 11 00:00:00 EST 2018