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Invitrogen
B1 Bradykinin Receptor Polyclonal Antibody
FIGURE: 1 / 6
B1 Bradykinin Receptor Antibody (PA5-33360) in IHC (P)
Immunohistochemistry analysis of B1 Bradykinin Receptor in human nasal mucosa. Samples were incubated with B1 Bradykinin Receptor polyclonal antibody (Product # PA5-33360). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33360
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human BDKRB1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550741
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Panda, Bovine, Horse (89%) Pig (83%).
Target Information
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B1 bradykinin receptor; B1R; Bk b1 receptor; BK-1 receptor; BKRB1; bradykinin B1 receptor; bradykinin receptor 1; bradykinin receptor B2
Gene Aliases: B1BKR; B1R; BDKRB1; BDKRB2; BKB1R; BKR1; BRADYB1
UniProt ID: (Human) P46663
Entrez Gene ID: (Human) 623
negative regulation of protein phosphorylation
positive regulation of leukocyte migration
inflammatory response
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
response to mechanical stimulus
cell migration
sensory perception of pain
negative regulation of cell growth
response to lipopolysaccharide
negative regulation of blood pressure
positive regulation of release of sequestered calcium ion into cytosol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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