Abnova

B4GALT4 Polyclonal Antibody, MaxPab™

View all (12) B4GALT4 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

H00008702-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

B4GALT4 (AAH04523.1, 1 a.a. approximately 344 a.a) full-length human protein.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGFNLTFHLS YKFRLLLLLT LCLTVVGWAT SNYFVGAIQE IPKAKEFMAN FHKTLILGKG KTLTNEASTK KVELDNCPSV SPYLRGQSKL IFKPDLTLEE VQAENPKVSR GRYRPEECKA LQRVAILVPH RNREKHLMYL LEHLHPFLQR QQLDYGIYVI HQAEGKKFNR AKLLNVGYLE ALKEENWDCF IFHDVDLVPE NDFNLYKCEE HPKHLVVGRN STGYRLRYSG YFGGVTALSR EQFFKVNGFS NNYWGWGGED DDLRLRVELQ RMKISRPLPE VGKYTMVFHT RDKGNEVNAE RMKLLHQVSR VWRTDGLSSC SYKLVSVEHN PLYINITVDF WFGA

Target Information

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Beta-1,4-galactosyltransferase 4; beta-1,4-galactosyltransferase IV; Beta-1,4-GalTase 4; beta-N-acetylglucosaminyl; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 4; Lactotriaosylceramide beta-1,4-galactosyltransferase; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4

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Gene Aliases: 9130402O08Rik; B4Gal-T4; B4galt-IV; B4GALT4; beta4Gal-T4; beta4GalT-IV; UNQ552/PRO1109

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UniProt ID: (Human) O60513, (Mouse) Q9JJ04

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Entrez Gene ID: (Human) 8702, (Mouse) 56375

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Function(s)
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity galactosyltransferase activity metal ion binding alpha-1,6-mannosyltransferase activity alpha-1,2-mannosyltransferase activity mannosyltransferase activity alpha-1,3-mannosyltransferase activity alpha-1,3-galactosyltransferase activity molecular_function UDP-glucose:glycoprotein glucosyltransferase activity glycolipid mannosyltransferase activity oligosaccharyl transferase activity dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity acetylglucosaminyltransferase activity acetylgalactosaminyltransferase activity fucosyltransferase activity O antigen polymerase activity lipopolysaccharide-1,6-galactosyltransferase activity transferase activity transferase activity, transferring glycosyl groups cellulose synthase activity 9-phenanthrol UDP-glucuronosyltransferase activity 1-phenanthrol glycosyltransferase activity 9-phenanthrol glycosyltransferase activity 1,2-dihydroxy-phenanthrene glycosyltransferase activity phenanthrol glycosyltransferase activity beta-1,4-mannosyltransferase activity alpha-1,2-galactosyltransferase activity dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity lipopolysaccharide-1,5-galactosyltransferase activity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity inositol phosphoceramide synthase activity glucosyltransferase activity alpha-(1->3)-fucosyltransferase activity alpha-(1->6)-fucosyltransferase activity indole-3-butyrate beta-glucosyltransferase activity salicylic acid glucosyltransferase (ester-forming) activity salicylic acid glucosyltransferase (glucoside-forming) activity benzoic acid glucosyltransferase activity chondroitin hydrolase activity dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity cytokinin 9-beta-glucosyltransferase activity glycosyltransferase
Process(es)
protein glycosylation membrane lipid metabolic process keratan sulfate biosynthetic process carbohydrate metabolic process biological_process
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