Product References
NaAsO2 regulates TLR4/MyD88/NF-κB signaling pathway through DNMT1/SOCS1 to cause apoptosis and inflammation in hepatic BRL-3A cells.
Biological trace element research
Li S,Zhang J,Ma M,Zhang M,Li L,Chen W,Li S
Mon Jan 01 00:00:00 EST 2024
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
Molecular medicine reports
Duan J,Yuan W,Jiang J,Wang J,Yan X,Liu F,Liu A
Wed Feb 01 00:00:00 EST 2023
The development and evaluation of hyaluronic acid coated mitochondrial targeting liposomes for celastrol delivery.
Drug delivery
Xiao S,Huang S,Yang X,Lei Y,Chang M,Hu J,Meng Y,Zheng G,Chen X
Fri Dec 01 00:00:00 EST 2023
Renal transporter OAT1 and PPAR-α pathway co-contribute to icaritin-induced nephrotoxicity.
Phytotherapy research : PTR
Wang D,Liu J,Chen X,Chen J,Zhao T,Du J,Wang C,Meng Q,Sun H,Wang F,Liu K,Wu J
Wed Feb 01 00:00:00 EST 2023
YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.
International journal of molecular sciences
Huang P,Liu M,Zhang J,Zhong X,Zhong C
Mon Feb 20 00:00:00 EST 2023
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
ACS applied materials & interfaces
Yi T,Qian J,Ye Y,Zhang H,Jin X,Wang M,Yang Z,Zhang W,Wen L,Zhang Y
Wed Jan 11 00:00:00 EST 2023
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling.
Cell stress & chaperones
Zhang MW,Li XT,Zhang ZZ,Liu Y,Song JW,Liu XM,Chen YH,Wang N,Guo Y,Liang LR,Zhong JC
Sun Jan 01 00:00:00 EST 2023
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Neuroscience
Chen C,Fan P,Zhang L,Xue K,Hu J,Huang J,Lu W,Xu J,Xu S,Qiu G,Ran J,Gan S
Wed Feb 01 00:00:00 EST 2023
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
Biochemical genetics
He Y,Zhang B,Han D,Du Y,Zhang X,Wang H,Yue Z,Shang P
Tue Aug 01 00:00:00 EDT 2023
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
International journal of molecular sciences
Ma M,Luan X,Zheng H,Wang X,Wang S,Shen T,Ren D
Thu Jan 05 00:00:00 EST 2023
Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.
Journal of inorganic biochemistry
Liu J,Wu Y,Yang G,Liu Z,Liu X
Wed Feb 01 00:00:00 EST 2023
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Molecular biology reports
Qu YM,Chen A,Zhao X,Wang Z,Guo D,Shao SL,Tao YY,Li QJ,Wang MY,Ma WS
Wed Feb 01 00:00:00 EST 2023
MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells.
The Science of the total environment
Hu Z,Linn N,Li Q,Zhang K,Liao J,Han Q,Zhang H,Guo J,Hu L,Pan J,Li Y,Tang Z
Wed Feb 01 00:00:00 EST 2023
Mass spectrometry-based metabolomics reveal Dendrobium huoshanense polysaccharide effects and potential mechanism of N-methyl-N'-nitro-N-nitrosoguanidine -induced damage in GES-1 cells.
Journal of ethnopharmacology
Xie H,Hu M,Yu J,Yang X,Li J,Yu N,Han L,Peng D
Wed Jun 28 00:00:00 EDT 2023
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Epigenomics
Zhao J,Liu J,Liu S,Tian S,Yuan H,Li S
Wed Mar 01 00:00:00 EST 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
PM2.5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway.
Chemosphere
Ming Y,Zhou X,Liu G,Abudupataer M,Zhu S,Xiang B,Yin X,Lai H,Sun Y,Wang C,Li J,Zhu K
Wed Feb 01 00:00:00 EST 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Kidney international
Li J,Sun X,Yang N,Ni J,Xie H,Guo H,Wang X,Zhou L,Liu J,Chen S,Wang X,Zhang Y,Yu C,Zhang W,Lu L
Sun Jan 01 00:00:00 EST 2023
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Leukemia research
Deng X,Zeng Y,Qiu X,Zhong M,Xiong X,Luo M,Zhang J,Chen X
Sat Jul 01 00:00:00 EDT 2023
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
CNS neuroscience & therapeutics
Shen K,Wu D,Sun B,Zhu Y,Wang H,Zou W,Ma Y,Lu Z
Sun Jan 01 00:00:00 EST 2023
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Food & function
Yu X,Zhang Y,Pei K,Tan J,Tian H,Xu T,Liu F,Peng N,Huang Y,Huang X,Huang X,Wu J,Liu Q,Zeng L,Hua W,Huang X
Thu May 11 00:00:00 EDT 2023
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
Neural regeneration research
Wang J,He P,Tian Q,Luo Y,He Y,Liu C,Gong P,Guo Y,Ye Q,Li M
Fri Sep 01 00:00:00 EDT 2023
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
Breast cancer research : BCR
Ouyang D,Hong T,Fu M,Li Y,Zeng L,Chen Q,He H,Wen Y,Cheng Y,Zhou M,Zou Q,Yi W
Fri Feb 10 00:00:00 EST 2023
Reactive oxygen species-mediated endoplasmic reticulum stress contributes to osteocyte death induced by orthodontic compressive force.
Microscopy research and technique
Yan M,Zhang Y,Niu W,Liu K,Xue L,Zhou K
Wed Nov 01 00:00:00 EDT 2023
MiR-155 promotes inflammation and apoptosis via targeting SIRT1 in hypoxic-ischemic brain damage.
Experimental neurology
Ke F,Wang H,Geng J,Jing X,Fang F,Fang C,Zhang BH
Sat Apr 01 00:00:00 EDT 2023
Nicotinamide Mononucleotide Adenylyl Transferase 2 Inhibition Aggravates Neurological Damage after Traumatic Brain Injury in a Rat Model.
Journal of Korean Neurosurgical Society
Gu X,Ni H,Kan X,Chen C,Zhou Z,Ding Z,Li D,Liu B
Sat Jul 01 00:00:00 EDT 2023
Probiotic powder ameliorates colorectal cancer by regulating Bifidobacterium animalis, Clostridium cocleatum, and immune cell composition.
PloS one
Yang X,Cao Q,Ma B,Xia Y,Liu M,Tian J,Chen J,Su C,Duan X
Wed Mar 15 00:00:00 EDT 2023
OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.
Cell proliferation
Zhao F,Zhu J,Zhang M,Luo Y,Li Y,Shi L,Huang J,Shadekejiang H,Dong S,Wu X
Tue Aug 01 00:00:00 EDT 2023
Compressive stress induces spinal vertebral growth plate chondrocytes apoptosis via Piezo1.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Chen F,Sun M,Peng F,Lai Y,Jiang Z,Zhang W,Li T,Jing X
Tue Aug 01 00:00:00 EDT 2023
Compressive stress induces spinal vertebral growth plate chondrocytes apoptosis via Piezo1.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Chen F,Sun M,Peng F,Lai Y,Jiang Z,Zhang W,Li T,Jing X
Tue Aug 01 00:00:00 EDT 2023
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Environmental toxicology
Xi Y,Chi Z,Tao X,Zhai X,Zhao Z,Ren J,Yang S,Dong D
Mon May 01 00:00:00 EDT 2023
4-vinylcyclohexene diepoxide induces apoptosis by excessive reactive oxygen species and DNA damage in human ovarian granulosa cells.
Toxicology in vitro : an international journal published in association with BIBRA
Song W,Qiu YT,Li XZ,Sun QY,Chen LN
Fri Sep 01 00:00:00 EDT 2023
Molecular docking and in vitro experiments verified that kaempferol induced apoptosis and inhibited human HepG2 cell proliferation by targeting BAX, CDK1, and JUN.
Molecular and cellular biochemistry
Zhang Q,Chen L,Gao M,Wang S,Meng L,Guo L
Sat Apr 01 00:00:00 EDT 2023
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
Mediators of inflammation
Tan Z,Dong F,Wu L,Feng Y,Zhang M,Zhang F
Fri Apr 28 00:00:00 EDT 2023
Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China.
Research in veterinary science
Yan P,Jia YC,Zhang XL,Zhou YY,Guo Y,Yin RL,Yuan J,Wang LX,Guo ZB,Wang JY,Wang X,Yin RH
Mon May 01 00:00:00 EDT 2023
Matrine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis and Apoptosis.
Inflammation
Xiao Y,Yu Y,Hu L,Yang Y,Yuan Y,Zhang W,Luo J,Yu L
Sun Oct 01 00:00:00 EDT 2023
Matrine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis and Apoptosis.
Inflammation
Xiao Y,Yu Y,Hu L,Yang Y,Yuan Y,Zhang W,Luo J,Yu L
Sun Oct 01 00:00:00 EDT 2023
DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hou S,Cheng Y,Wang Z,Xia L,Wang J,Wang H,Sun J,Ma J,Yan Y
Sun Jan 01 00:00:00 EST 2023
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
PloS one
Zhu Y,Sun W,Jiang X,Bai R,Luo Y,Gao Y,Li S,Huang Z,Gong Y,Xie C
Fri Feb 03 00:00:00 EST 2023
Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li X,Lin Z,Wang P,Zhou C,Xu J,Lin J,Lin D,Zhang D
Thu Jun 01 00:00:00 EDT 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
Normothermic ex vivo heart perfusion with NLRP3 inflammasome inhibitor Mcc950 treatment improves cardiac function of circulatory death hearts after transplantation.
Frontiers in cardiovascular medicine
Xu L,Zeng Z,Niu C,Liu D,Lin S,Liu X,Szabó G,Lu J,Zheng S,Zhou P
Tue Apr 04 00:00:00 EDT 2023
TFP5 attenuates cyclin-dependent kinase 5-mediated islet β-cell damage in diabetes.
Chemical biology & drug design
Liu S,Li B,Ma D,Tao Y,Song J,Bao L,Zhang G,Luo H,Cao S,E J,Zheng Y
Sat Jul 01 00:00:00 EDT 2023
Spinal cord tissue engineering via covalent interaction between biomaterials and cells.
Science advances
Liu W,Xu B,Zhao S,Han S,Quan R,Liu W,Ji C,Chen B,Xiao Z,Yin M,Yin Y,Dai J,Zhao Y
Fri Feb 10 00:00:00 EST 2023
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Brain pathology (Zurich, Switzerland)
Chen Y,Dong Y,Zhang ZL,Han J,Chen FS,Tong XY,Ma H
Sun Jan 01 00:00:00 EST 2023
Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.
Antioxidants (Basel, Switzerland)
Ren W,Wang Z,Cao J,Dong Y,Wang T,Chen Y
Fri Apr 28 00:00:00 EDT 2023
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Molecular medicine reports
Jiang B,Feng L,Yang T,Guo W,Li Y,Wang T,Liu C,Su H
Wed Feb 01 00:00:00 EST 2023
The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.
Reproductive biology
Huang X,Liu X,Zhang X,Yang Y,Gao H,Gao J,Bao H,Zhao L,Yang G,Zhang Y,Liu D
Fri Sep 01 00:00:00 EDT 2023
Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway.
Journal of ethnopharmacology
Xiu Z,Tang S,Kong P,Yan M,Tong X,Liu X,Liang X,Li R,Duan Y
Thu Oct 05 00:00:00 EDT 2023
Role of Orai3-Mediated Store-Operated Calcium Entry in Radiation-Induced Brain Microvascular Endothelial Cell Injury.
International journal of molecular sciences
Wu Q,Fang Y,Huang X,Zheng F,Ma S,Zhang X,Han T,Gao H,Shen B
Thu Apr 06 00:00:00 EDT 2023
Alleviative Effect of Threonine on Cadmium-Induced Liver Injury in Mice.
Biological trace element research
Fang Z,Li Y,Wang J,Wang X,Huang L,Sun L,Deng Q
Fri Sep 01 00:00:00 EDT 2023
TRIM38 protects H9c2 cells from hypoxia/reoxygenation injury via the TRAF6/TAK1/NF-κB signalling pathway.
PeerJ
Lu Z,Deng M,Ma G,Chen L
Tue Jan 17 00:00:00 EST 2023
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Experimental and therapeutic medicine
Li T,Huang S,Yan W,Zhang Y,Guo Q
Tue Feb 01 00:00:00 EST 2022
Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.
Journal of Zhejiang University. Science. B
Yang X,Yu X,Zhao Z,He Y,Zhang J,Su X,Sun N,Fan Z
Mon Jan 31 00:00:00 EST 2022
Brevilin A Inhibits VEGF-Induced Angiogenesis through ROS-Dependent Mitochondrial Dysfunction.
Oxidative medicine and cellular longevity
Wei B,Hao Z,Zheng H,Qin Y,Zhao F,Shi L
Tue Jan 10 00:00:00 EST 2023
Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition.
Journal of orthopaedic translation
Cao Y,Li Y,Fu SC,Shen J,Zhang H,Jiang C,Shu-Hang Yung P
Sun May 01 00:00:00 EDT 2022
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
International journal of molecular sciences
Jian Y,Yuan S,Yang J,Lei Y,Li X,Liu W
Wed Aug 31 00:00:00 EDT 2022
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Small (Weinheim an der Bergstrasse, Germany)
Guan G,Zhang Q,Jiang Z,Liu J,Wan J,Jin P,Lv Q
Thu Dec 01 00:00:00 EST 2022
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Frontiers in molecular biosciences
Zou P,Zhang X,Zhang R,Chai X,Zhao Y,Li E,Zhang Q,Yan R,Yang J,Liao B
Sat Apr 09 00:00:00 EDT 2022
OEA alleviates apoptosis in diabetic rats with myocardial ischemia/reperfusion injury by regulating the PI3K/Akt signaling pathway through activation of TRPV1.
Frontiers in pharmacology
Yao E,Luo L,Lin C,Wen J,Li Y,Ren T,Chen Y,Huang J,Jin X
Fri Dec 02 00:00:00 EST 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
International journal of biological macromolecules
Wang Y,Wang Q,Duan L,Li X,Yang W,Huang T,Kong M,Guan F,Ma S
Thu Dec 01 00:00:00 EST 2022
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Translational oncology
Cai J,Gao L,Wang Y,Li Y,Ye Z,Tong S,Yan T,Sun Q,Xu Y,Jiang H,Zhang S,Zhao L,Yang J,Chen Q
Sun May 01 00:00:00 EDT 2022
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Translational oncology
Cai J,Gao L,Wang Y,Li Y,Ye Z,Tong S,Yan T,Sun Q,Xu Y,Jiang H,Zhang S,Zhao L,Yang J,Chen Q
Sun May 01 00:00:00 EDT 2022
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Translational oncology
Cai J,Gao L,Wang Y,Li Y,Ye Z,Tong S,Yan T,Sun Q,Xu Y,Jiang H,Zhang S,Zhao L,Yang J,Chen Q
Sun May 01 00:00:00 EDT 2022
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Translational oncology
Cai J,Gao L,Wang Y,Li Y,Ye Z,Tong S,Yan T,Sun Q,Xu Y,Jiang H,Zhang S,Zhao L,Yang J,Chen Q
Sun May 01 00:00:00 EDT 2022
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury.
Inflammation
Cao Y,Fan M,Pei Y,Su L,Xiao W,Chen F,Huang J,Liu X,Gu Z,Zhang Z,Yuan F,Jiang Y,Han X
Fri Apr 01 00:00:00 EDT 2022
Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cao L,Zhou S,Qiu X,Qiu S
Thu Sep 01 00:00:00 EDT 2022
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Discover. Oncology
Luan H,Yan L,Zhao Y,Ding X,Cao L
Mon Oct 03 00:00:00 EDT 2022
Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.
Oxidative medicine and cellular longevity
Zhang Y,Xing CJ,Liu X,Li YH,Jia J,Feng JG,Yang CJ,Chen Y,Zhou J
Thu May 19 00:00:00 EDT 2022
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Journal of cardiovascular translational research
Wang K,Li Z,Sun Y,Liu X,Ma W,Ding Y,Hong J,Qian L,Xu D
Mon Aug 01 00:00:00 EDT 2022
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Cell death & disease
Tang X,Liang Y,Sun G,He Q,Hou Z,Jiang X,Gao P,Qu H
Tue Oct 04 00:00:00 EDT 2022
Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways.
International journal of molecular medicine
Zhang Y,Li Y,Wang Q,Zheng D,Feng X,Zhao W,Cai L,Zhang Q,Xu H,Fu H
Tue Feb 01 00:00:00 EST 2022
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Molecular carcinogenesis
Fang J,Ma Y,Li Y,Li J,Zhang X,Han X,Ma S,Guan F
Tue Nov 01 00:00:00 EDT 2022
Effects of Ganfule capsule on microbial and metabolic profiles in anti-hepatocellular carcinoma.
Journal of applied microbiology
Xu F,Li H,Pan Y,Zeng Y,Li J,Li S
Tue Mar 01 00:00:00 EST 2022
DEAD-box helicase 56 functions as an oncogene promote cell proliferation and invasion in gastric cancer via the FOXO1/p21 Cip1/c-Myc signaling pathway.
Bioengineered
Wang J,Wang Y,Wang J,Zhang S,Yu Z,Zheng K,Fu Z,Wang C,Huang W,Chen J
Sun May 01 00:00:00 EDT 2022
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Drug design, development and therapy
Li Y,Li C,Xiong Y,Fang B,Lin X,Huang Q
Wed Jun 15 00:00:00 EDT 2022
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Cell death discovery
Lu X,Huang X,Xu H,Lu S,You S,Xu J,Zhan Q,Dong C,Zhang N,Zhang Y,Cao L,Zhang X,Zhang N,Zhang L
Tue Oct 18 00:00:00 EDT 2022
Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene.
Frontiers in oncology
Zhang J,Tang Z,Guo X,Wang Y,Zhou Y,Cai W
Wed Nov 29 00:00:00 EST 2023
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
EBioMedicine
Luo Y,Zhang Y,Han X,Yuan Y,Zhou Y,Gao Y,Yu H,Zhang J,Shi Y,Duan Y,Zhao X,Yan S,Hao H,Dai C,Zhao S,Shi J,Li W,Zhang S,Xu W,Fang N,Gong Y,Li Y
Mon Aug 01 00:00:00 EDT 2022
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Cell biology and toxicology
Wang H,Ai J,Shopit A,Niu M,Ahmed N,Tesfaldet T,Tang Z,Li X,Jamalat Y,Chu P,Peng J,Ma X,Qaed E,Han G,Zhang W,Wang J,Tang Z
Wed Jun 01 00:00:00 EDT 2022
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Environmental toxicology
Hu Y,Zhang P,Shi Y,Dong X,Wu Y,Dong D,Li E,Fan Y
Tue Mar 01 00:00:00 EST 2022
Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer.
Chinese medicine
Yu F,Tan W,Chen Z,Shen X,Mo X,Mo X,He J,Deng Z,Wang J,Luo Z,Yang J
Thu Sep 29 00:00:00 EDT 2022
Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.
Journal of medicinal chemistry
Yuan Y,Fu D,Xu Y,Wang X,Deng X,Zhou S,Du F,Cui X,Deng Y,Tang Z
Thu Nov 24 00:00:00 EST 2022
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Biochemical pharmacology
Zhao J,Chen S,Yang C,Zhou M,Yang T,Sun B,Zhu J,Zhang H,Lu Q,Li L,Yang Z,Song B,Shen W,Yi S,Dai S
Wed Jun 01 00:00:00 EDT 2022
Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification.
Drug design, development and therapy
Shu W,Wang Z,Zhao R,Shi R,Zhang J,Zhang W,Wang H
Fri Jun 24 00:00:00 EDT 2022
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling.
Toxicology and applied pharmacology
Feng X,Jiang J,Sun L,Zhou Q
Fri Apr 01 00:00:00 EDT 2022
Inflammation and fibrosis in the coal dust-exposed lung described by confocal Raman spectroscopy.
PeerJ
Wang W,Mu M,Zou Y,Li B,Cao H,Hu D,Tao X
Mon Jan 16 00:00:00 EST 2023
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
ACS nano
Li Y,Cen Y,Fang Y,Tang S,Li S,Ren Y,Zhang H,Lu W,Xu J
Tue Aug 23 00:00:00 EDT 2022
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Kan Y,Song M,Cui X,Yang Q,Zang Y,Li Q,Li Y,Cai W,Chen Y,Weng X,Wang Y,Zhu X
Tue Feb 01 00:00:00 EST 2022
Acrylonitrile exposure triggers ovarian inflammation and decreases oocyte quality probably via mitochondrial dysfunction induced apoptosis in mice.
Chemico-biological interactions
Luo YS,He QK,Sun MX,Qiao FX,Liu YC,Xu CL,Xu ZR,Zhao SC,Wang HL,Qi ZQ,Liu Y
Wed Jun 01 00:00:00 EDT 2022
Neddylation Inhibition Causes Impaired Mouse Embryo Quality and Blastocyst Hatching Failure Through Elevated Oxidative Stress and Reduced IL-1β.
Frontiers in immunology
Yang G,Chen J,He Y,Luo H,Yuan H,Chen L,Huang L,Mao F,Hu S,Qian Y,Miao C,Feng R
Fri Jul 22 00:00:00 EDT 2022
LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy.
Science China. Life sciences
Zhang Q,Li D,Dong X,Zhang X,Liu J,Peng L,Meng B,Hua Q,Pei X,Zhao L,Hu X,Zhang Y,Pan Z,Lu Y,Yang B
Wed Jun 01 00:00:00 EDT 2022
Circ_0076305 facilitates prostate cancer development via sponging miR-411-5p and regulating PGK1.
Andrologia
Ding X,Sun J,Zhang X
Fri Jul 01 00:00:00 EDT 2022
SIRT1 Is Involved in the Neuroprotection of Pterostilbene Against Amyloid β 25-35-Induced Cognitive Deficits in Mice.
Frontiers in pharmacology
Zhu L,Lu F,Zhang X,Liu S,Mu P
Sun Nov 05 00:00:00 EDT 2023
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
Overexpression of Aquaporin-3 Alleviates Hyperosmolarity-Induced Nucleus Pulposus Cell Apoptosis via Regulating the ERK1/2 Pathway.
Pain research & management
Zhang Z,Zhao C,Zhang R,Wang Y,Hu Y,Zhou Q,Li P
Wed Apr 20 00:00:00 EDT 2022
Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia-reperfusion injury after cardiac surgery with cardiopulmonary bypass.
Cellular & molecular biology letters
Wu T,Shi G,Ji Z,Wang S,Geng L,Guo Z
Tue Oct 25 00:00:00 EDT 2022
2-PMAP Ameliorates Cerebral Vasospasm and Brain Injury after Subarachnoid Hemorrhage by Regulating Neuro-Inflammation in Rats.
Cells
Wu CH,Tsai HP,Su YF,Tsai CY,Lu YY,Lin CL
Wed Jan 12 00:00:00 EST 2022
Hernandezine Regulates Proliferation and Autophagy-Induced Apoptosis in Melanoma Cells.
Journal of natural products
Wang X,Li X,Xia Y,Wang D,Li X,Liu L,Zheng Q,Li D,Jiang Q
Fri May 27 00:00:00 EDT 2022
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Journal of cellular and molecular medicine
Chai H,Zhang ZH,Fang JY,She C,Geng C,Xu W
Mon Aug 01 00:00:00 EDT 2022
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
Communications biology
Ding N,Zhang Y,Huang M,Liu J,Wang C,Zhang C,Cao J,Zhang Q,Jiang L
Wed Dec 07 00:00:00 EST 2022
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
Communications biology
Ding N,Zhang Y,Huang M,Liu J,Wang C,Zhang C,Cao J,Zhang Q,Jiang L
Wed Dec 07 00:00:00 EST 2022
Integrated Bioinformatic Analysis Reveals TXNRD1 as a Novel Biomarker and Potential Therapeutic Target in Idiopathic Pulmonary Arterial Hypertension.
Frontiers in medicine
Lin W,Tang Y,Zhang M,Liang B,Wang M,Zha L,Yu Z
Mon Jan 02 00:00:00 EST 2023
Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell-Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after Circulatory Death Hearts.
Stem cells international
Zeng Z,Xu L,Xu Y,Ruan Y,Liu D,Li J,Niu C,Zheng S,Zhou P,Xiao Z
Tue Nov 29 00:00:00 EST 2022
Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.
Frontiers in pharmacology
Xia B,Li Q,Wu J,Yuan X,Wang F,Lu X,Huang C,Zheng K,Yang R,Yin L,Liu K,You Q
Sat Jul 16 00:00:00 EDT 2022
Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.
Evidence-based complementary and alternative medicine : eCAM
Zheng Z,Yu Z,Xu B,Zhou Y,Xing Y,Li Q,Tang W,Peng F
Sat Jul 16 00:00:00 EDT 2022
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Translational oncology
Lin Z,Yang S,Zhou Y,Hou Z,Li L,Meng M,Ge C,Zeng B,Lai J,Gao H,Zhao Y,Xie Y,He S,Tang W,Li R,Tan J,Wang W
Tue Feb 01 00:00:00 EST 2022
Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury.
Chinese medicine
Xu H,Xu S,Li L,Wu Y,Mai S,Xie Y,Tan Y,Li A,Xue F,He X,Li Y
Thu Nov 24 00:00:00 EST 2022
Integrated metabolomics, network pharmacology and biological verification to reveal the mechanisms of Nauclea officinalis treatment of LPS-induced acute lung injury.
Chinese medicine
Xu H,Xu S,Li L,Wu Y,Mai S,Xie Y,Tan Y,Li A,Xue F,He X,Li Y
Thu Nov 24 00:00:00 EST 2022
Hydroxysafflor yellow A attenuates oxidative stress injury-induced apoptosis in the nucleus pulposus cell line and regulates extracellular matrix balance via CA XII.
Experimental and therapeutic medicine
Yang S,Liao W
Tue Feb 01 00:00:00 EST 2022
miR-125b Disrupts Mitochondrial Dynamics via Targeting Mitofusin 1 in Cisplatin-Induced Acute Kidney Injury.
Kidney diseases (Basel, Switzerland)
Zhao Y,Lang Y,Zhang M,Liang S,Zhu X,Liu Z
Tue Mar 01 00:00:00 EST 2022
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Cancers
Xing J,Chen W,Chen K,Zhu S,Lin F,Qi Y,Zhang Y,Han S,Rao T,Ruan Y,Zhao S,Yu W,Cheng F
Fri Sep 30 00:00:00 EDT 2022
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
International journal of biological macromolecules
Zhang D,Chang R,Ren Y,He Y,Guo S,Guan F,Yao M
Mon Oct 31 00:00:00 EDT 2022
IL-18BP Improves Early Graft Function and Survival in Lewis-Brown Norway Rat Orthotopic Liver Transplantation Model.
Biomolecules
Meng Q,Wu W,Zhang W,Yuan J,Yang L,Zhang X,Tao K
Thu Dec 01 00:00:00 EST 2022
β-Hydroxybutyrate against Cisplatin-Induced acute kidney injury via inhibiting NLRP3 inflammasome and oxidative stress.
International immunopharmacology
Luo S,Yang M,Han Y,Zhao H,Jiang N,Li L,Chen W,Li C,Yang J,Liu Y,Liu C,Zhao C,Sun L
Sat Oct 01 00:00:00 EDT 2022
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Toxicology
Lei S,Feng Y,Huang P,Chen B,Bao K,Wu Q,Zhang H,Huang X
Fri Jul 01 00:00:00 EDT 2022
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Ecotoxicology and environmental safety
Wu J,Yang C,Yang M,Liang Z,Wu Y,Kong X,Fan H,Wang S,Ning C,Xiao W,Jin Y,Yi J,Yuan Z
Wed Jun 01 00:00:00 EDT 2022
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
International journal of nanomedicine
Fu Y,Yuan P,Zheng Y,Wei Y,Gao L,Ruan Y,Chen Y,Li P,Feng W,Zheng X
Tue Apr 12 00:00:00 EDT 2022
Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H2O2 enhances their ability to treat intervertebral disc degeneration.
Stem cell research & therapy
Zhang YY,Hu ZL,Qi YH,Li HY,Chang X,Gao XX,Liu CH,Li YY,Lou JH,Zhai Y,Li CQ
Tue Jul 26 00:00:00 EDT 2022
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Molecules (Basel, Switzerland)
Zhou M,Dai Y,Ma Y,Yan Y,Hua M,Gao Q,Geng X,Zhou Q
Tue Jun 14 00:00:00 EDT 2022
Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury.
Laboratory investigation; a journal of technical methods and pathology
Li B,Liu L
Thu Sep 01 00:00:00 EDT 2022
Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury.
Laboratory investigation; a journal of technical methods and pathology
Li B,Liu L
Thu Sep 01 00:00:00 EDT 2022
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Oxidative medicine and cellular longevity
Wang M,Yang X,Zhou Q,Guo Y,Chen Y,Song L,Yang J,Li L,Luo L
Mon Nov 28 00:00:00 EST 2022
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Oxidative medicine and cellular longevity
Wang M,Yang X,Zhou Q,Guo Y,Chen Y,Song L,Yang J,Li L,Luo L
Mon Nov 28 00:00:00 EST 2022
β-Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts.
IUBMB life
Guo Q,Li Y,Chen Y,Ji J,Zheng S,Xu X,Zhang B,Ye J
Wed Jun 01 00:00:00 EDT 2022
Cardiotoxicity of patulin was found in H9c2 cells.
Toxicon : official journal of the International Society on Toxinology
Zhang B,Liang H,Huang K,Li J,Xu D,Huang C,Li Y
Tue Feb 01 00:00:00 EST 2022
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Pharmacological research
Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S
Wed Jun 01 00:00:00 EDT 2022
Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin.
Ecotoxicology and environmental safety
Wang J,Ding L,Wang K,Huang R,Yu W,Yan B,Wang H,Zhang C,Yang Z,Liu Z
Mon Aug 01 00:00:00 EDT 2022
Enhanced Intracellular Reactive Oxygen Species by Photodynamic Therapy Effectively Promotes Chemoresistant Cell Death.
International journal of biological sciences
Xu X,Wang C,Zhang P,Gao X,Guan W,Wang F,Li X,Yuan J,Dou H,Xu G
Mon Mar 28 00:00:00 EDT 2022
Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR-144-3p/IGF2R axis.
Drug development research
Yuan D,Guo T,Qian H,Ge H,Zhao Y,Huang A,Wang X,Cao X,Zhu D,He C,Yu H
Thu Sep 01 00:00:00 EDT 2022
Depletion of PARP10 inhibits the growth and metastatic potential of oral squamous cell carcinoma.
Frontiers in genetics
Zhou Z,Wei B,Liu Y,Liu T,Zeng S,Gan J,Qi G
Wed Nov 02 00:00:00 EDT 2022
Methylmercury induces lysosomal membrane permeabilization through JNK-activated Bax lysosomal translocation in neuronal cells.
Toxicology letters
Tianji L,Dingbang H,Xiao C,Xiaojing M,Fei Z,Bin W
Tue Mar 01 00:00:00 EST 2022
Methylmercury induces lysosomal membrane permeabilization through JNK-activated Bax lysosomal translocation in neuronal cells.
Toxicology letters
Tianji L,Dingbang H,Xiao C,Xiaojing M,Fei Z,Bin W
Tue Mar 01 00:00:00 EST 2022
High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.
Brain research bulletin
Yan J,Zhang F,Niu L,Wang X,Lu X,Ma C,Zhang C,Song J,Zhang Z
Wed Jun 01 00:00:00 EDT 2022
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fu Y,Yuan P,Zheng Y,Gao L,Wei Y,Chen Y,Li P,Ruan Y,Zheng X,Feng W
Wed Jun 01 00:00:00 EDT 2022
Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system.
Asian journal of pharmaceutical sciences
Wu N,Tu Y,Fan G,Ding J,Luo J,Wang W,Zhang C,Yuan C,Zhang H,Chen P,Tan S,Xiao H
Tue Mar 01 00:00:00 EST 2022
Leonurine Protects Bone Mesenchymal Stem Cells from Oxidative Stress by Activating Mitophagy through PI3K/Akt/mTOR Pathway.
Cells
Zhao B,Peng Q,Wang D,Zhou R,Wang R,Zhu Y,Qi S
Tue May 24 00:00:00 EDT 2022
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Phytotherapy research : PTR
Wang L,Cheng L,Ma L,Ahmad Farooqi A,Qiao G,Zhang Y,Ye H,Liu M,Huang J,Yang X,Lin X,Cao S
Sat Jan 01 00:00:00 EST 2022
GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts.
European journal of pharmacology
Wang SH,Cui LG,Su XL,Komal S,Ni RC,Zang MX,Zhang LR,Han SN
Tue Apr 05 00:00:00 EDT 2022
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Nutrients
Zhong Y,Li Z,Jin R,Yao Y,He S,Lei M,Wang X,Shi C,Gao L,Peng X
Thu Nov 24 00:00:00 EST 2022
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Evidence-based complementary and alternative medicine : eCAM
Peng H,Jin L,Zhang Q,Shen Y,Wang Z,Zhou F,Yu Q
Sat Jul 16 00:00:00 EDT 2022
Limosilactobacillus reuteri SLZX19-12 Protects the Colon from Infection by Enhancing Stability of the Gut Microbiota and Barrier Integrity and Reducing Inflammation.
Microbiology spectrum
Wu J,Lin Z,Wang X,Zhao Y,Zhao J,Liu H,Johnston LJ,Lu L,Ma X
Wed Jun 29 00:00:00 EDT 2022
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway.
International immunopharmacology
Fu Y,Gao J,Li Y,Yang X,Zhang Y
Tue Feb 01 00:00:00 EST 2022
Extraction Optimization, Structural Characterization, and Anti-Hepatoma Activity of Acidic Polysaccharides From Scutellaria barbata D. Don.
Frontiers in pharmacology
Su W,Wu L,Liang Q,Lin X,Xu X,Yu S,Lin Y,Zhou J,Fu Y,Gao X,Zhang B,Li L,Li D,Yin Y,Song G
Sat Jul 16 00:00:00 EDT 2022
miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1.
Environmental toxicology
Xin X,Duan L,Yang H,Yu H,Bao Y,Jia D,Wu N,Qiao Y
Fri Apr 01 00:00:00 EDT 2022
Effect of Fumonisin B1 on Proliferation and Apoptosis of Intestinal Porcine Epithelial Cells.
Toxins
Wang T,Lei H,Zhou L,Tang M,Liu Q,Long F,Li Q,Su J
Sat Jul 09 00:00:00 EDT 2022
Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis.
Cell communication and signaling : CCS
Huang L,An X,Zhu Y,Zhang K,Xiao L,Yao X,Zeng X,Liang S,Yu J
Tue Aug 16 00:00:00 EDT 2022
LncRNA PCAT19 induced by SP1 and acted as oncogene in gastric cancer competitively binding to miR429 and upregulating DHX9.
Journal of Cancer
Xiao L,Yuan W,Huang C,Luo Q,Xiao R,Chen ZH
Tue Jan 04 00:00:00 EST 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC.
Journal of translational medicine
Du X,Zhang X,Dong J,Zou N,Guo D,Yao W,Wang X,Li S,Song C,Yan K,Shen W,Zhu S
Sat Nov 05 00:00:00 EDT 2022
Blocking PARP activity with the inhibitor veliparib enhances radiotherapy sensitivity in endometrial carcinoma.
Journal of clinical laboratory analysis
Wang J,Xing W,Lin Y,Uskenbayeva N,Yan H,Xu Y,Fang L
Sun May 01 00:00:00 EDT 2022
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Cancers
Xie Y,Shi Z,Qian Y,Jiang C,Liu W,Liu B,Jiang B
Sat Jul 23 00:00:00 EDT 2022
Ursolic acid inhibits the activation of smoothened-independent non-canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade.
Phytotherapy research : PTR
Chen L,Liu M,Yang H,Ren S,Sun Q,Zhao H,Ming T,Tang S,Tao Q,Zeng S,Meng X,Xu H
Thu Sep 01 00:00:00 EDT 2022
Design, semi-synthesis and bioactivity evaluation of novel podophyllotoxin derivatives as potent anti-tumor agents.
Bioorganic chemistry
Sun W,Sun F,Meng J,Cao X,Zhao S,Wang C,Li L,Jiang P
Thu Sep 01 00:00:00 EDT 2022
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Redox biology
Xu Z,Xu J,Sun S,Lin W,Li Y,Lu Q,Li F,Yang Z,Lu Y,Liu W
Mon Aug 01 00:00:00 EDT 2022
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Chemico-biological interactions
Tan J,Sun M,Yin J,Zhou Q,Zhao R,Chen Q,Sun H,Jiang C,Li S,He Y
Thu Dec 01 00:00:00 EST 2022
Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.
Biochemical and biophysical research communications
Li J,Jiang R,Hou Y,Lin A
Sat Aug 27 00:00:00 EDT 2022
The lncRNA-AK046375 Upregulates Metallothionein-2 by Sequestering miR-491-5p to Relieve the Brain Oxidative Stress Burden after Traumatic Brain Injury.
Oxidative medicine and cellular longevity
Tang W,Chai W,Du D,Xia Y,Wu Y,Jiang L,Cheng C,Guo Z,Sun X,Huang Z,Zhong J
Thu Mar 17 00:00:00 EDT 2022
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
International immunopharmacology
Huo K,Ma KG,Guo QY,Duan P,Xu J
Fri Jul 01 00:00:00 EDT 2022
Protective Effect of Resveratrol on Immortalized Duck Intestinal Epithelial Cells Exposed to H2O2.
Molecules (Basel, Switzerland)
Zhou N,Tian Y,Wu H,Cao Y,Li R,Zou K,Xu W,Lu L
Tue May 31 00:00:00 EDT 2022
Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.
Journal of cellular physiology
Lin D,Qin R,Guo L
Sat Jan 01 00:00:00 EST 2022
miR-204-5p is sponged by TUG1 to aggravate neuron damage induced by focal cerebral ischemia and reperfusion injury through upregulating COX2.
Cell death discovery
Xiang P,Hu J,Wang H,Luo Y,Gu C,Tan X,Tu Y,Guo W,Chen L,Gao L,Chen R,Yang J
Mon Feb 28 00:00:00 EST 2022
Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies.
Aging
Wu X,Wang Y,Fan X,Xu X,Sun W
Fri Jan 07 00:00:00 EST 2022
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Tissue & cell
Yu X,Jiang N,Li J,Li X,He S
Wed Jun 01 00:00:00 EDT 2022
Mechanism Study of Cinnamomi Ramulus and Paris polyphylla Sm. Drug Pair in the Treatment of Adenomyosis by Network Pharmacology and Experimental Validation.
Evidence-based complementary and alternative medicine : eCAM
Zhang K,Zhou Z,Wang C,Yu M,Zhang Y,Shi Y,Wang X,Liu Y,Xu L,Shi W,Liu Z
Sat Aug 27 00:00:00 EDT 2022
Mechanism Study of Cinnamomi Ramulus and Paris polyphylla Sm. Drug Pair in the Treatment of Adenomyosis by Network Pharmacology and Experimental Validation.
Evidence-based complementary and alternative medicine : eCAM
Zhang K,Zhou Z,Wang C,Yu M,Zhang Y,Shi Y,Wang X,Liu Y,Xu L,Shi W,Liu Z
Sat Aug 27 00:00:00 EDT 2022
Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Zhang Y,Zhao X,Man X,Ma Y,Zhang W,Wang Y,Lei X,Bai S
Sat Oct 01 00:00:00 EDT 2022
Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Zhang Y,Zhao X,Man X,Ma Y,Zhang W,Wang Y,Lei X,Bai S
Sat Oct 01 00:00:00 EDT 2022
Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment.
Evidence-based complementary and alternative medicine : eCAM
Lou H,Zhang Y,Fang J,Jin Y
Sat Jul 16 00:00:00 EDT 2022
Clinical significance of mitogen-activated protein kinase kinase kinases in hepatitis B virus -related hepatocellular carcinoma and underlying mechanism exploration.
Bioengineered
Liu Z,Zhou X,Zheng P,Bu C,Yan X,Yu H,Xu Y
Tue Mar 01 00:00:00 EST 2022
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Diabetes
Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L
Sun May 01 00:00:00 EDT 2022
Anti-melanoma effect and action mechanism of a novel chitosan-based composite hydrogel containing hydroxyapatite nanoparticles.
Regenerative biomaterials
Xu K,Wang Y,Xie Y,Zhang X,Chen W,Li Z,Wang T,Yang X,Guo B,Wang L,Zhu X,Zhang X
Sat Aug 13 00:00:00 EDT 2022
Sesquiterpene lactones from Elephantopus scaber exhibit cytotoxic effects on glioma cells by targeting GSTP1.
Bioorganic chemistry
Yan QL,Wang XY,Bai M,Zhang X,Song SJ,Yao GD
Thu Dec 01 00:00:00 EST 2022
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Frontiers in pharmacology
Pan B,Xia Y,Fang S,Ai J,Wang K,Zhang J,Du C,Chen Y,Liu L,Yan S
Wed Nov 02 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Bioactive substances in the stratum corneum of the epidermis found as indicators of skin damage due to sun exposure.
Photodermatology, photoimmunology & photomedicine
Fukunaga A,Fukushima S,Iwata H,Nakahara M,Sasaki R,Baba N,Matsunaka H,Murakami Y,Furue M,Nishigori C
Sun May 01 00:00:00 EDT 2022
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Photodiagnosis and photodynamic therapy
Li Z,Xiao Z,Feng Y,Wang Q,Teng M
Tue Mar 01 00:00:00 EST 2022
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure.
Cell stress & chaperones
Liu Y,Shi H,Hu Y,Yao R,Liu P,Yang Y,Li S
Tue Nov 01 00:00:00 EDT 2022
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Journal of cellular and molecular medicine
Xiao H,Peng L,Jiang D,Liu Y,Zhu L,Li Z,Geng J,Xie B,Huang X,Wang J,Dai H,Wang C
Tue Nov 01 00:00:00 EDT 2022
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Journal of cellular and molecular medicine
Xiao H,Peng L,Jiang D,Liu Y,Zhu L,Li Z,Geng J,Xie B,Huang X,Wang J,Dai H,Wang C
Tue Nov 01 00:00:00 EDT 2022
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Frontiers in molecular neuroscience
Guo J,Zhang L,Bu Y,Li W,Hu J,Li J
Fri Nov 18 00:00:00 EST 2022
Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner.
Renal failure
Wei JY,Hu MY,Chen XQ,Lei FY,Wei JS,Chen J,Qin XK,Qin YH
Thu Dec 01 00:00:00 EST 2022
Systemically Silencing Long Non-coding RNAs Maclpil With Short Interfering RNA Nanoparticles Alleviates Experimental Ischemic Stroke by Promoting Macrophage Apoptosis and Anti-inflammatory Activation.
Frontiers in cardiovascular medicine
Wang Y,Liu C,Chen Y,Chen T,Han T,Xue L,Xu B
Tue May 24 00:00:00 EDT 2022
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Varier KM,Dan G,Liu W,Wu G,Xiao C,Lei H,Ling T,Jiang Y,Chen Y,Ben-David Y,Li Y,Zhang N,Gajendran B,Shen X
Thu Dec 01 00:00:00 EST 2022
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Journal of cellular and molecular medicine
Cheng Y,Hu Y,Wang H,Zhao Z,Jiang X,Zhang Y,Zhang J,Tong Y,Qiu X
Sun Aug 01 00:00:00 EDT 2021
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
IUBMB life
Zhu J,Han S
Thu Apr 01 00:00:00 EDT 2021
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
American journal of translational research
Zhang JJ,Song CG,Dai JM,Zhang XQ,Lin P,Li L,Yang XM,Chen ZN
Tue Jun 22 00:00:00 EDT 2021
Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways.
Evidence-based complementary and alternative medicine : eCAM
Zhang H,Zhao J,Lu Q,Sun B,Liu X,Yang C,Li S,Li L,Yi S,Yang Z,Xu J
Tue Nov 23 00:00:00 EST 2021
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Genetics and molecular biology
Yang X,Jin J,Yang J,Zhou L,Mi S,Qi G
Sat Dec 04 00:00:00 EST 2021
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Toxicology and applied pharmacology
Pang JL,Huang FH,Zhang YH,Wu Y,Ge XM,Li S,Li X
Mon Nov 01 00:00:00 EDT 2021
Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
Naunyn-Schmiedeberg's archives of pharmacology
Li L,Yang M,Li C,Liu Y
Mon Nov 01 00:00:00 EDT 2021
Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7.
Cell biology international
Jiang L,Wang M,Sun R,Lin Z,Liu R,Cai H,Tang Z,Zhang R
Sun Aug 01 00:00:00 EDT 2021
Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle.
Frontiers in physiology
Wang D,Song M,Shen LF,Han L,Zhu P,Jia X,Shang GK,Cao Y,Zhang W,Zhong M,Wang ZH
Sun May 01 00:00:00 EDT 2022
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Oncology reports
Feng X,Cao A,Qin T,Zhang Q,Fan S,Wang B,Song B,Yu X,Li L
Mon Nov 01 00:00:00 EDT 2021
HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.
The international journal of biochemistry & cell biology
Shao Y,Zhu F,Zhu S,Bai L
Thu Jul 01 00:00:00 EDT 2021
The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function.
Journal of Cancer
Wang H,Ren R,Yang Z,Cai J,Du S,Shen X
Sat Feb 06 00:00:00 EST 2021
The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function.
Journal of Cancer
Wang H,Ren R,Yang Z,Cai J,Du S,Shen X
Sat Feb 06 00:00:00 EST 2021
The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function.
Journal of Cancer
Wang H,Ren R,Yang Z,Cai J,Du S,Shen X
Sat Feb 06 00:00:00 EST 2021
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
Frontiers in pharmacology
Xie B,Zeng Z,Liao S,Zhou C,Wu L,Xu D
Sat Oct 23 00:00:00 EDT 2021
Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway.
Frontiers in cell and developmental biology
Cao Y,Chen Z,Hu J,Feng J,Zhu Z,Fan Y,Lin Q,Ding G
Fri Jan 07 00:00:00 EST 2022
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
Pharmacological research
Sun X,Zhu H,Cao R,Zhang J,Wang X
Thu Jul 01 00:00:00 EDT 2021
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Cancer cell international
Liu X,Yang J,Yang C,Huang X,Han M,Kang F,Li J
Thu Nov 25 00:00:00 EST 2021
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
Theranostics
Jiang L,Yin X,Chen YH,Chen Y,Jiang W,Zheng H,Huang FQ,Liu B,Zhou W,Qi LW,Li J
Mon Aug 16 00:00:00 EDT 2021
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Archives of biochemistry and biophysics
Han J,Wang L,Lv H,Liu J,Dong Y,Shi L,Ji Q
Sat Oct 30 00:00:00 EDT 2021
Upregulation of PPPDE1 contributes to anorectal malformations via the mitochondrial apoptosis pathway during hindgut development in rats.
Experimental cell research
Li SY,Wang CY,Zhao JJ,Long CY,Xiao YX,Tang XB,Yuan ZW,Bai YZ
Sat May 15 00:00:00 EDT 2021
Toxicological and physiological effects of successive exposure to ochratoxin A at food regulatory limits.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wei W,Liu C,Ke P,Chen X,Zhou T,Xu J,Zhou Y
Sat May 01 00:00:00 EDT 2021
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Frontiers in cell and developmental biology
Fei H,Xiang P,Luo W,Tan X,Gu C,Liu M,Chen M,Wang Q,Yang J
Tue Aug 24 00:00:00 EDT 2021
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Journal of cellular and molecular medicine
Chen W,Zhao S,Yu W,Rao T,Ruan Y,Zhu S,Xia Y,Song H,Cheng F
Mon Nov 01 00:00:00 EDT 2021
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Journal of cellular and molecular medicine
Chen W,Zhao S,Yu W,Rao T,Ruan Y,Zhu S,Xia Y,Song H,Cheng F
Mon Nov 01 00:00:00 EDT 2021
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Journal of cellular and molecular medicine
Chen W,Zhao S,Yu W,Rao T,Ruan Y,Zhu S,Xia Y,Song H,Cheng F
Mon Nov 01 00:00:00 EDT 2021
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Journal of cellular and molecular medicine
Chen W,Zhao S,Yu W,Rao T,Ruan Y,Zhu S,Xia Y,Song H,Cheng F
Mon Nov 01 00:00:00 EDT 2021
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Journal of Cancer
Deng X,Zuo M,Pei Z,Xie Y,Yang Z,Zhang Z,Jiang M,Kuang D
Tue Sep 07 00:00:00 EDT 2021
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
Journal of Cancer
Zou N,Zhang X,Li S,Li Y,Zhao Y,Yang X,Zhu S
Fri Jul 09 00:00:00 EDT 2021
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Oncology reports
Chen S,Xiao L,Peng H,Wang Z,Xie J
Sat May 01 00:00:00 EDT 2021
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Scientific reports
Zhao Y,Liu X,Zheng Y,Liu W,Ding C
Mon Oct 18 00:00:00 EDT 2021
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Oxidative medicine and cellular longevity
Liu J,Wu Q,Yang T,Yang F,Guo T,Zhou Y,Han S,Luo Y,Guo T,Luo F,Lin Q
Fri Feb 04 00:00:00 EST 2022
Protective Effect of Flavonoids from a Deep-Sea-Derived Arthrinium sp. against ox-LDL-Induced Oxidative Injury through Activating the AKT/Nrf2/HO-1 Pathway in Vascular Endothelial Cells.
Marine drugs
Hou JR,Wang YH,Zhong YN,Che TT,Hu Y,Bao J,Meng N
Sat Dec 18 00:00:00 EST 2021
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Acta biochimica et biophysica Sinica
Yagudin T,Zhao Y,Gao H,Zhang Y,Yang Y,Zhang X,Ma W,Daba TM,Ishmetov V,Kang K,Yang B,Pan Z
Tue Jan 12 00:00:00 EST 2021
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2.
BioMed research international
Zhao W,Wu Y,Ye F,Huang S,Chen H,Zhou R,Jiang W
Wed May 26 00:00:00 EDT 2021
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Evidence-based complementary and alternative medicine : eCAM
Liu K,Lv M,Ji X,Lou L,Nie B,Zhao J,Wu A,Zhao M
Sat Nov 13 00:00:00 EST 2021
NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.
Frontiers in cell and developmental biology
Dang NN,Li XB,Zhang M,Han C,Fan XY,Huang SH
Tue Sep 07 00:00:00 EDT 2021
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Frontiers in genetics
Yang L,Li L,Chang P,Wei M,Chen J,Zhu C,Jia J
Sat Nov 13 00:00:00 EST 2021
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Frontiers in genetics
Peng HH,Wang JN,Xiao LF,Yan M,Chen SP,Wang L,Yang K
Tue May 18 00:00:00 EDT 2021
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Journal of natural products
Zhang R,Zhang Y,Xin X,Huang G,Zhang N,Zeng Q,Tang L,Attaribo T,Lee KS,Jin BR,Gui Z
Fri May 28 00:00:00 EDT 2021
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Life sciences
Chen J,Zhang W,Pan C,Fan J,Zhong X,Tang S
Thu Apr 15 00:00:00 EDT 2021
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Molecular carcinogenesis
Li Y,Zhu X,Yang M,Wang Y,Li J,Fang J,Guo W,Ma S,Guan F
Thu Jul 01 00:00:00 EDT 2021
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Molecular carcinogenesis
Li Y,Zhu X,Yang M,Wang Y,Li J,Fang J,Guo W,Ma S,Guan F
Thu Jul 01 00:00:00 EDT 2021
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Journal of cellular and molecular medicine
Liu S,Hu J,Shi C,Sun L,Yan W,Song Y
Tue Jun 01 00:00:00 EDT 2021
miR-101-3p sensitizes lung adenocarcinoma cells to irradiation via targeting BIRC5.
Oncology letters
Meng X,Sun Y,Liu S,Mu Y
Thu Apr 01 00:00:00 EDT 2021
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Medical science monitor : international medical journal of experimental and clinical research
Pan H,Xu Y,Cai Q,Wu M,Ding M
Fri Jun 04 00:00:00 EDT 2021
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
Acta pharmaceutica Sinica. B
Wu X,Liu L,Zheng Q,Hao H,Ye H,Li P,Yang H
Mon Nov 01 00:00:00 EDT 2021
Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2.
Acta pharmaceutica Sinica. B
Wu X,Liu L,Zheng Q,Hao H,Ye H,Li P,Yang H
Mon Nov 01 00:00:00 EDT 2021
Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis.
Journal of nanobiotechnology
Liu S,Xu A,Gao Y,Xie Y,Liu Z,Sun M,Mao H,Wang X
Thu Mar 25 00:00:00 EDT 2021
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Nutrition and cancer
Zhang D,Li C,Zhang L,Li B,Wang Y,Wang R,Chen Z,Xu L,Liu T
Thu Feb 24 00:00:00 EST 2022
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Food science & nutrition
Chen Y,Liang J,Liang X,Chen J,Wang Y,Cao J,Sun C,Ye J,Chen Q
Thu Apr 01 00:00:00 EDT 2021
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Zhou J,Hao S,Guo H,Yu H,Guo Z,Liu L
Thu Jul 15 00:00:00 EDT 2021
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
International immunopharmacology
Wang F,Younis M,Luo Y,Zhang L,Yuan L
Tue Jun 01 00:00:00 EDT 2021
Histone deacetylase 10 exerts anti-tumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
IUBMB life
Zhu J,Han S
Fri Jan 22 00:00:00 EST 2021
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Journal of cellular and molecular medicine
Li L,Cheng SQ,Guo W,Cai ZY,Sun YQ,Huang XX,Yang J,Ji J,Chen YY,Dong YF,Cheng H,Sun XL
Fri Oct 01 00:00:00 EDT 2021
The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of Prmt7/Akt3 Pathway.
International journal of molecular sciences
Wang B,Zhang M,Guo J,Liu Z,Zhou R,Guo F,Li K,Mu Y
Thu Nov 11 00:00:00 EST 2021
Structural analysis of Panax ginseng glycoproteins and its anti-oligoasthenozoospermia effect in vivo.
International journal of biological macromolecules
Shan M,Zhang X,Fang X,Tian J,Song L,Chen Y,Qiu Z,Zhu D,Luo H,Wang Z
Wed Dec 15 00:00:00 EST 2021
Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy.
International journal of medical sciences
Chen CA,Huang YC,Lo JJ,Wang SH,Huang SH,Wu SH
Wed Mar 09 00:00:00 EST 2022
The inhibitory effect Polygonum Cillinerve polysaccharide on transmissible gastroenteritis virus of swine.
Research in veterinary science
Pan X,Zhou Y,Duan X,Cui J,Liu J,Song X,Ma W,Zhang W,Liu Y,Fan Y
Mon Nov 01 00:00:00 EDT 2021
O-GlcNAc / Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress.
Cryobiology
Liu Y,Xu B,Hu Y,Liu P,Lian S,Lv H,Yang Y,Ji H,Yang H,Liu J,Yao R,Li S
Tue Jun 01 00:00:00 EDT 2021
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Journal of bone oncology
Guo H,Peng J,Hu J,Chang S,Liu H,Luo H,Chen X,Tang H,Chen Y
Wed Dec 01 00:00:00 EST 2021
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zeng L,Zou Q,Huang P,Xiong L,Cheng Y,Chen Q,Li Y,He H,Yi W,Wei W
Fri Oct 01 00:00:00 EDT 2021
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Molecular immunology
Xu Y,Yu J,Ma C,Gong Z,Wu X,Deng G
Mon Feb 01 00:00:00 EST 2021
Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study.
International journal of nanomedicine
Zhang P,Yu B,Jin X,Zhao T,Ye F,Liu X,Li P,Zheng X,Chen W,Li Q
Fri Jul 23 00:00:00 EDT 2021
Dracomolphin A-E, new lignans from Dracocephalum moldavica.
Fitoterapia
Zhang H,Wang S,Liu Q,Zheng H,Liu X,Wang X,Shen T,Ren D
Thu Apr 01 00:00:00 EDT 2021
Metformin attenuates H2O2-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Experimental and therapeutic medicine
Yang K,Pei L,Zhou S,Tao L,Zhu Y
Mon Nov 01 00:00:00 EDT 2021
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Journal of neuroimmunology
Zhao X,Yang P
Wed Sep 15 00:00:00 EDT 2021
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Frontiers in veterinary science
Ou G,Jiang X,Gao A,Li X,Lin Z,Pei S
Wed Feb 23 00:00:00 EST 2022
Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30.
Cell death discovery
Yan D,Li X,Yang Q,Huang Q,Yao L,Zhang P,Sun W,Lin S,Dou QP,Liu J,Chen X
Wed Aug 11 00:00:00 EDT 2021
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Experimental & molecular medicine
Yang J,Zhang M,Yang D,Ma Y,Tang Y,Xing M,Li L,Chen L,Jin Y,Ma C
Mon Nov 01 00:00:00 EDT 2021
Sonodynamic Effects of a Novel Ether-Group Modified Porphyrin Derivative Combined With Pulsed Low-Intensity Ultrasound on PC-9 Cells.
Frontiers in pharmacology
Jin Y,Zhou Q,Geng J,Meng Q,Wei Z,Ding M,Zhou J,Zeng Y,Cao W,Liu F,Yu Y
Fri Dec 24 00:00:00 EST 2021
G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer.
British journal of cancer
Zhao J,Fu X,Chen H,Min L,Sun J,Yin J,Guo J,Li H,Tang Z,Ruan Y,Wang X,Sun Y,Huang L
Fri Jan 01 00:00:00 EST 2021
Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
Journal of nanobiotechnology
Zheng S,Wang J,Ding N,Chen W,Chen H,Xue M,Chen F,Ni J,Wang Z,Lin Z,Jiang H,Liu X,Wang L
Sun Nov 21 00:00:00 EST 2021
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
International journal of medical sciences
Zhang L,Cai Q,Lin S,Chen B,Jia B,Ye R,Weygant N,Chu J,Peng J
Wed Nov 03 00:00:00 EDT 2021
Design, Synthesis, and Activity Evaluation of Novel Acyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.
Journal of medicinal chemistry
Hao EJ,Li GX,Liang YR,Xie MS,Wang DC,Jiang XH,Cheng JY,Shi ZX,Wang Y,Guo HM
Thu Feb 25 00:00:00 EST 2021
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Oxidative medicine and cellular longevity
Ma N,Yang X,Qi C,Yu Q,Zhu C,Ren H
Wed May 19 00:00:00 EDT 2021
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
International journal of molecular sciences
Bian Q,Chen B,Weng B,Chu D,Tang X,Yan S,Yin Y,Ran M
Mon Aug 30 00:00:00 EDT 2021
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Frontiers in molecular biosciences
Liu Y,Liu P,Hu Y,Cao Y,Lu J,Yang Y,Lv H,Lian S,Xu B,Li S
Tue Aug 17 00:00:00 EDT 2021
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Journal of cellular biochemistry
Zheng Y,Nie P,Xu S
Mon Jun 01 00:00:00 EDT 2020
Anti-CD19 mAb-conjugated human serum albumin nanoparticles effectively deliver doxorubicin to B-lymphoblastic leukemia cells.
Die Pharmazie
Pan H,Li S,Li M,Tao Q,Jia J,Li W,Wang L,Guo Z,Ma K,Liu Y,Cui C
Wed Jul 01 00:00:00 EDT 2020
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Bioorganic chemistry
Li B,Zhu F,He F,Huang Q,Liu X,Wu T,Zhao T,Qiu Y,Wu Z,Xue Y,Fang M
Sun Mar 01 00:00:00 EST 2020
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Toxicology letters
Lin Y,Yu M,Fan T
Sun Mar 01 00:00:00 EST 2020
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Molecular medicine reports
Wu Y,Zhao Y,He X,He Z,Wang T,Wan L,Chen L,Yan N
Wed Jan 01 00:00:00 EST 2020
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Aging
Sha L,Ma D,Chen C
Sun Dec 13 00:00:00 EST 2020
Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway.
Chemico-biological interactions
Yang J,Zhu XJ,Jin MZ,Cao ZW,Ren YY,Gu ZW
Sat Jan 25 00:00:00 EST 2020
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Cell proliferation
Jiang N,Zhao H,Han Y,Li L,Xiong S,Zeng L,Xiao Y,Wei L,Xiong X,Gao P,Yang M,Liu Y,Sun L
Sun Nov 01 00:00:00 EDT 2020
Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression.
BioMed research international
Zou Y,Li R,Kuang D,Zuo M,Li W,Tong W,Jiang L,Zhou M,Chen Y,Gong W,Liu L,Tou F
Thu Apr 01 00:00:00 EDT 2021
Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang Z,Guo J,Cui K,Du Y,Zhao H,Zhu L,Weng L,Tang W,Guo J,Zhang T,Shi X,Zong H,Jin S,Ma W
Sun Nov 01 00:00:00 EDT 2020
Epigenetic upregulation of HOXC10 in non-small lung cancer cells.
Aging
Li M,Alsager JS,Wang Z,Cheng L,Shan B
Sun Jul 19 00:00:00 EDT 2020
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Journal of experimental & clinical cancer research : CR
Feng J,Dai W,Mao Y,Wu L,Li J,Chen K,Yu Q,Kong R,Li S,Zhang J,Ji J,Wu J,Mo W,Xu X,Guo C
Thu Jan 30 00:00:00 EST 2020
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Evidence-based complementary and alternative medicine : eCAM
Wang CH,Yang JM,Guo YB,Shen J,Pei XH
Mon Sep 28 00:00:00 EDT 2020
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Niu Q,Sun W,Chen Q,Long Y,Cao W,Wen S,Li A,Dong F,Shi H
Mon Jul 20 00:00:00 EDT 2020
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
International immunopharmacology
Ji J,Wu L,Feng J,Mo W,Wu J,Yu Q,Li S,Zhang J,Dai W,Xu X,Mao Y,Xu S,Chen K,Li J,Guo C
Wed Jul 01 00:00:00 EDT 2020
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Cancer science
Ding XY,Hu HY,Huang KN,Wei RQ,Min J,Qi C,Tang H,Qin X
Sat Feb 01 00:00:00 EST 2020
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
DNA and cell biology
Zhang J,Chen Y,Lin J,Jia R,An T,Dong T,Zhang Y,Yang X
Sun Mar 01 00:00:00 EST 2020
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
BMC cancer
Feng Q,Bian X,Liu X,Wang Y,Zhou H,Ma X,Quan C,Yao Y,Zheng Z
Thu Jul 16 00:00:00 EDT 2020
Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury.
Journal of cellular and molecular medicine
Hu X,Li R,Wu Y,Li Y,Zhong X,Zhang G,Kang Y,Liu S,Xie L,Ye J,Xiao J
Wed Jul 01 00:00:00 EDT 2020
NFIB functions as an oncogene in estrogen receptor-positive breast cancer and is regulated by miR-205-5p.
Pathology, research and practice
Chen H,Yu C,Shen L,Wu Y,Wu D,Wang Z,Song G,Chen L,Hong Y
Tue Dec 01 00:00:00 EST 2020
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
International journal of biological macromolecules
Yang K,Lu T,Zhan L,Zhou C,Zhang N,Lei S,Wang Y,Yang J,Yan M,Lv G,Chen S
Wed Apr 15 00:00:00 EDT 2020
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
International journal of clinical and experimental pathology
Li L,Peng X,Guo L,Zhao Y,Cheng Q
Thu Jun 11 00:00:00 EDT 2020
PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Feng AL,Han X,Meng X,Chen Z,Li Q,Shu W,Dai H,Zhu J,Yang Z
Thu Oct 01 00:00:00 EDT 2020
AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Xiong S,Han Y,Gao P,Zhao H,Jiang N,Sun L
Tue Jun 08 00:00:00 EDT 2021
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Chemico-biological interactions
Wang J,Liu X,Zheng H,Liu Q,Zhang H,Wang X,Shen T,Wang S,Ren D
Sun Nov 01 00:00:00 EDT 2020
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Molecular medicine reports
Chen X,Ji S,Si J,Zhang X,Wang X,Guo Y,Zou X
Tue Dec 01 00:00:00 EST 2020
Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in mice.
Brain research bulletin
Chen B,Yang L,Chen J,Chen Y,Zhang L,Wang L,Li X,Li Y,Yu H
Fri Mar 01 00:00:00 EST 2019
Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in mice.
Brain research bulletin
Chen B,Yang L,Chen J,Chen Y,Zhang L,Wang L,Li X,Li Y,Yu H
Fri Mar 01 00:00:00 EST 2019
Tamibarotene Improves Hippocampus Injury Induced by Focal Cerebral Ischemia-Reperfusion via Modulating PI3K/Akt Pathway in Rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Tian X,An R,Luo Y,Li M,Xu L,Dong Z
Mon Jul 01 00:00:00 EDT 2019
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
International journal of molecular sciences
Zhang L,Wang F,Zhang Q,Liang Q,Wang S,Xian M,Wang F
Tue Oct 29 00:00:00 EDT 2019
NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway.
Experimental and therapeutic medicine
Li F,Wu JT,Wang PF,Qu LZ
Tue Oct 01 00:00:00 EDT 2019
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
Feng J,Wu L,Ji J,Chen K,Yu Q,Zhang J,Chen J,Mao Y,Wang F,Dai W,Xu L,Wu J,Guo C
Fri May 17 00:00:00 EDT 2019
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.
Cancer management and research
Ma Y,Guan L,Han Y,Zhou Y,Li X,Liu Y,Zhang X,Zhang W,Li X,Wang S,Lu W
Thu Oct 01 00:00:00 EDT 2020
Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.
International journal of molecular sciences
Liu P,Yao R,Shi H,Liu Y,Lian S,Yang Y,Yang H,Li S
Sat Mar 23 00:00:00 EDT 2019
Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1.
Biochemical pharmacology
Li TS,Chen L,Wang SC,Yang YZ,Xu HJ,Gu HM,Zhao XJ,Dong P,Pan Y,Shang ZQ,Zhang XQ,Kong LD
Thu Aug 01 00:00:00 EDT 2019
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Stress (Amsterdam, Netherlands)
Shi H,Yao R,Lian S,Liu P,Liu Y,Yang YY,Yang H,Li S
Wed May 01 00:00:00 EDT 2019
Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury.
PloS one
Zilberman-Itskovich S,Abu-Hamad R,Zarura R,Sova M,Hachmo Y,Stark M,Neuman S,Slavin S,Efrati S
Fri Mar 06 00:00:00 EST 2020
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Oncology letters
Song T,Ma K,Zhao C,Yang J,Liu J
Thu Aug 01 00:00:00 EDT 2019
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
International journal of molecular medicine
Zhang P,Hua L,Hou H,Du X,He Z,Liu M,Hu X,Yan N
Sat Dec 01 00:00:00 EST 2018
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
International journal of molecular medicine
Zhang P,Hua L,Hou H,Du X,He Z,Liu M,Hu X,Yan N
Sat Dec 01 00:00:00 EST 2018
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Neurochemical research
Li M,Tian X,An R,Yang M,Zhang Q,Xiang F,Liu H,Wang Y,Xu L,Dong Z
Fri Jun 01 00:00:00 EDT 2018
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Neurochemical research
Li M,Tian X,An R,Yang M,Zhang Q,Xiang F,Liu H,Wang Y,Xu L,Dong Z
Fri Jun 01 00:00:00 EDT 2018
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
Molecular medicine reports
Xue S,He W,Zeng X,Tang Z,Feng S,Zhong Z,Xiong Y,Wang Y,Ye Q
Sun Jul 01 00:00:00 EDT 2018
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2‑ARE signaling pathway.
Molecular medicine reports
Xue S,He W,Zeng X,Tang Z,Feng S,Zhong Z,Xiong Y,Wang Y,Ye Q
Sun Jul 01 00:00:00 EDT 2018
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
Pathology, research and practice
Yin Y,Xu M,Gao J,Li M
Sat Sep 01 00:00:00 EDT 2018
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
Pathology, research and practice
Yin Y,Xu M,Gao J,Li M
Sat Sep 01 00:00:00 EDT 2018
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Oncology letters
Lu K,Rui G,Liu F,Yang L,Deng X,Shi S,Li Q
Mon Jan 01 00:00:00 EST 2018
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Oncology letters
Lu K,Rui G,Liu F,Yang L,Deng X,Shi S,Li Q
Mon Jan 01 00:00:00 EST 2018
DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells.
Oncology letters
Sun N,Zhang J,Zhang C,Zhao B,Jiao A
Thu Nov 01 00:00:00 EDT 2018
DNMTs inhibitor SGI-1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells.
Oncology letters
Sun N,Zhang J,Zhang C,Zhao B,Jiao A
Thu Nov 01 00:00:00 EDT 2018
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Experimental and therapeutic medicine
Yue X,Li M,Chen D,Xu Z,Sun S
Thu Nov 01 00:00:00 EDT 2018
UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells.
Experimental and therapeutic medicine
Yue X,Li M,Chen D,Xu Z,Sun S
Thu Nov 01 00:00:00 EDT 2018
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Experimental and therapeutic medicine
Liu Z,Xie J,Lin K,Qi L
Sat Dec 01 00:00:00 EST 2018
Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke.
Experimental and therapeutic medicine
Liu Z,Xie J,Lin K,Qi L
Sat Dec 01 00:00:00 EST 2018
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Experimental and therapeutic medicine
Feng J,Niu P,Chen K,Wu L,Liu T,Xu S,Li J,Li S,Wang W,Lu X,Yu Q,Liu N,Xu L,Wang F,Dai W,Xia Y,Fan X,Guo C
Fri Jun 01 00:00:00 EDT 2018
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Experimental and therapeutic medicine
Feng J,Niu P,Chen K,Wu L,Liu T,Xu S,Li J,Li S,Wang W,Lu X,Yu Q,Liu N,Xu L,Wang F,Dai W,Xia Y,Fan X,Guo C
Fri Jun 01 00:00:00 EDT 2018
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Experimental and therapeutic medicine
Feng J,Niu P,Chen K,Wu L,Liu T,Xu S,Li J,Li S,Wang W,Lu X,Yu Q,Liu N,Xu L,Wang F,Dai W,Xia Y,Fan X,Guo C
Fri Jun 01 00:00:00 EDT 2018
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Experimental and therapeutic medicine
Feng J,Niu P,Chen K,Wu L,Liu T,Xu S,Li J,Li S,Wang W,Lu X,Yu Q,Liu N,Xu L,Wang F,Dai W,Xia Y,Fan X,Guo C
Fri Jun 01 00:00:00 EDT 2018
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ou B,Tao W,Yang S,Feng J,Wang J,Yang T,Wu H,Huang Y,Tan L,Huang W,Feng Z,Mei Z
Wed Sep 30 00:00:00 EDT 2020
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ou B,Tao W,Yang S,Feng J,Wang J,Yang T,Wu H,Huang Y,Tan L,Huang W,Feng Z,Mei Z
Wed Sep 30 00:00:00 EDT 2020
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ou B,Tao W,Yang S,Feng J,Wang J,Yang T,Wu H,Huang Y,Tan L,Huang W,Feng Z,Mei Z
Wed Sep 30 00:00:00 EDT 2020
The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ou B,Tao W,Yang S,Feng J,Wang J,Yang T,Wu H,Huang Y,Tan L,Huang W,Feng Z,Mei Z
Wed Sep 30 00:00:00 EDT 2020
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.
Oncogene
Zeng K,Chen X,Hu X,Liu X,Xu T,Sun H,Pan Y,He B,Wang S
Mon Oct 01 00:00:00 EDT 2018
A small molecule targeting glutathione activates Nrf2 and inhibits cancer cell growth through promoting Keap-1 S-glutathionylation and inducing apoptosis.
RSC advances
Wang L,Qu G,Gao Y,Su L,Ye Q,Jiang F,Zhao B,Miao J
Tue Jan 02 00:00:00 EST 2018
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
International journal of molecular sciences
Yao R,Yang Y,Lian S,Shi H,Liu P,Liu Y,Yang H,Li S
Tue Sep 18 00:00:00 EDT 2018
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
International journal of molecular sciences
Yao R,Yang Y,Lian S,Shi H,Liu P,Liu Y,Yang H,Li S
Tue Sep 18 00:00:00 EDT 2018
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Molecular medicine reports
Shi X,Yang L,Xie J,Zhao Y,Cong J,Li Z,Li H,Cheng X,Fan J
Sat Sep 01 00:00:00 EDT 2018
Morroniside protects SK-N-SH human neuroblastoma cells against H2O2-induced damage.
International journal of molecular medicine
Zhang JX,Wang R,Xi J,Shen L,Zhu AY,Qi Q,Wang QY,Zhang LJ,Wang FC,Lü HZ,Hu JG
Wed Mar 01 00:00:00 EST 2017
Morroniside protects SK-N-SH human neuroblastoma cells against H2O2-induced damage.
International journal of molecular medicine
Zhang JX,Wang R,Xi J,Shen L,Zhu AY,Qi Q,Wang QY,Zhang LJ,Wang FC,Lü HZ,Hu JG
Wed Mar 01 00:00:00 EST 2017
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Molecular medicine reports
Zhao XS,Wu Q,Peng J,Pan LH,Ren Z,Liu HT,Jiang ZS,Wang GX,Tang ZH,Liu LS
Wed Feb 01 00:00:00 EST 2017
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression.
Molecular medicine reports
Zhao XS,Wu Q,Peng J,Pan LH,Ren Z,Liu HT,Jiang ZS,Wang GX,Tang ZH,Liu LS
Wed Feb 01 00:00:00 EST 2017
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Experimental and therapeutic medicine
Tang Z,Zhang Z,Tang Y,Qi L,Yang F,Wang Z
Fri Dec 01 00:00:00 EST 2017
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Experimental and therapeutic medicine
Tang Z,Zhang Z,Tang Y,Qi L,Yang F,Wang Z
Fri Dec 01 00:00:00 EST 2017
Mesenchymal stem cell conditioned medium alleviates oxidative stress injury induced by hydrogen peroxide via regulating miR143 and its target protein in hepatocytes.
BMC immunology
Xu X,Li D,Li X,Shi Q,Ju X
Tue Dec 19 00:00:00 EST 2017
Mesenchymal stem cell conditioned medium alleviates oxidative stress injury induced by hydrogen peroxide via regulating miR143 and its target protein in hepatocytes.
BMC immunology
Xu X,Li D,Li X,Shi Q,Ju X
Tue Dec 19 00:00:00 EST 2017
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Biochemical and biophysical research communications
Yang F,Shi L,Liang T,Ji L,Zhang G,Shen Y,Zhu F,Xu L
Sat Mar 25 00:00:00 EDT 2017
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu L,Wang C,Li J,Li S,Feng J,Liu T,Xu S,Wang W,Lu X,Chen K,Xia Y,Fan X,Guo C
Fri Dec 01 00:00:00 EST 2017
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu L,Wang C,Li J,Li S,Feng J,Liu T,Xu S,Wang W,Lu X,Chen K,Xia Y,Fan X,Guo C
Fri Dec 01 00:00:00 EST 2017
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
Scientific reports
Li B,Hou D,Guo H,Zhou H,Zhang S,Xu X,Liu Q,Zhang X,Zou Y,Gong Y,Shao C
Thu Mar 16 00:00:00 EDT 2017
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
Scientific reports
Li B,Hou D,Guo H,Zhou H,Zhang S,Xu X,Liu Q,Zhang X,Zou Y,Gong Y,Shao C
Thu Mar 16 00:00:00 EDT 2017
Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling.
International journal of endocrinology
Zhang C,Li L,Zhao B,Jiao A,Li X,Sun N,Zhang J
Wed May 18 00:00:00 EDT 2016
Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling.
International journal of endocrinology
Zhang C,Li L,Zhao B,Jiao A,Li X,Sun N,Zhang J
Wed May 18 00:00:00 EDT 2016
Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3.
In vitro cellular & developmental biology. Animal
Kong F,Wang H,Guo J,Peng M,Ji H,Yang H,Liu B,Wang J,Zhang X,Li S
Sun May 01 00:00:00 EDT 2016
Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3.
In vitro cellular & developmental biology. Animal
Kong F,Wang H,Guo J,Peng M,Ji H,Yang H,Liu B,Wang J,Zhang X,Li S
Sun May 01 00:00:00 EDT 2016
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.
Marine drugs
Luo J,Wu N,Jiang B,Wang L,Wang S,Li X,Wang B,Wang C,Shi D
Fri Jul 17 00:00:00 EDT 2015
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.
Marine drugs
Luo J,Wu N,Jiang B,Wang L,Wang S,Li X,Wang B,Wang C,Shi D
Fri Jul 17 00:00:00 EDT 2015