Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 9
Sequence of this protein is as follows: MTLQWAAVAT FLYAEIGLIL IFCLPFIPPQ RWQKIFSFNV WGKIATFWNK AFLTIIILLI VLFLDAVREV RKYSSVHTIE KSSTSRPDAY EHTQMKLFRS QRNLYISGFS LFFWLVLRRL VTLITQLAKE LSNKGVLKTQ AENTNKAAKK FMEENEKLKR ILKSHGKDEE CVLEAENKKL VEDQEKLKTE LRKTSDALSK AQNDVMEMKM QSERLSKEYD QLLKEHSELQ DRLERGNKKR L
Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
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Protein Aliases: B-cell receptor-associated protein 29; B-cell receptor-associated protein BAP29; BCR-associated protein 29
Gene Aliases: AW208404; BAP29; BCAP29
UniProt ID: (Human) Q9UHQ4, (Mouse) Q61334
Entrez Gene ID: (Human) 55973, (Mouse) 12033, (Rat) 298943
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