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BRD2 Antibody (PA5-95726) in IHC (P)
Immunohistochemistry analysis of BRD2 in paraffin-embedded mouse kidney. Samples were incubated with BRD2 Polyclonal antibody (Product # PA5-95726) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-95726
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 301-400 of human BRD2 (NP_0050951)
Conjugate
Form
Liquid
Concentration
1.24 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807528
Product Specific Information
Positive Samples: Mouse brain; Cellular Location: Nucleus
Immunogen sequence: SPPGSLEPKA ARLPPMRRES GRPIKPPRKD LPDSQQQHQS SKKGKLSEQL KHCNGILKEL LSKKHAAYAW PFYKPVDASA LGLHDYHDII KHPMDLSTVK
Target Information
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bromodomain-containing 2; Bromodomain-containing protein 2; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Fsrg-1; O27.1.1; Protein RING3; really interesting new gene 3 protein; RING3 protein
Gene Aliases: AW228947; BRD2; D17H6S113E; D6S113E; Frg-1; FSH; Fsrg-1; FSRG1; Kiaa4005; KIAA9001; mKIAA4005; NAT; O27.1.1; RING3; RNF3
UniProt ID: (Human) P25440, (Rat) Q6MGA9, (Mouse) Q7JJ13
Entrez Gene ID: (Human) 6046, (Rat) 294276, (Mouse) 14312
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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