Product References
Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours.
Frontiers in cell and developmental biology
Whiley PAF,Nathaniel B,Stanton PG,Hobbs RM,Loveland KL
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sat Aug 12 00:00:00 EDT 2023
R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.
iScience
Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X
12-1171-82 was used in Flow cytometry/Cell sorting to demonstrate that Phf6R274X plays a critical role in fine-tuning T cells and HSC homeostasis.
Fri Jun 16 00:00:00 EDT 2023
Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation.
Journal of innate immunity
Leong E,Pang Z,Stadnyk AW,Lin TJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Jul 07 00:00:00 EDT 2022
Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution.
Scientific reports
Rossi G,Giger S,Hübscher T,Lutolf MP
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression.
International journal of biological sciences
Li J,Li X,Sun W,Zhang J,Yan Q,Wu J,Jin J,Lu R,Miao D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Apr 15 00:00:00 EDT 2022
Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice.
Communications biology
Yang J,Sun M,Cheng R,Tan H,Liu C,Chen R,Zhang J,Yang Y,Gao X,Huang L
12-1171-82 was used in Flow Cytometry to describe a molecular mechanism of mitophagy activation which accounts for the pleiotropic effects of statins on the cardiovascular system and provides a potential therapeutic target for atherosclerosis.
Thu Feb 10 00:00:00 EST 2022
Preventive Effects of a Human Hematopoietic Mesenchymal Stem Cell (hHMSC) Therapy in Ovalbumin-Induced Food Allergy.
Biomedicines
Lee DG,Lee YJ,Park SH,Park HR,Kang H,Kim JE
12-1171-82 was used in Flow Cytometry to investigate the preventive effects of human hematopoietic mesenchymal stem cells in mice with ovalbumin-induced food allergy.
Mon Feb 21 00:00:00 EST 2022
Preventive Effects of a Human Hematopoietic Mesenchymal Stem Cell (hHMSC) Therapy in Ovalbumin-Induced Food Allergy.
Biomedicines
Lee DG,Lee YJ,Park SH,Park HR,Kang H,Kim JE
12-1171-82 was used in Flow Cytometry to investigate the preventive effects of human hematopoietic mesenchymal stem cells in mice with ovalbumin-induced food allergy.
Mon Feb 21 00:00:00 EST 2022
Hematopoietic stem cell transplantation ameliorates maternal diabetes-mediated gastrointestinal symptoms and autism-like behavior in mouse offspring.
Annals of the New York Academy of Sciences
Zeng J,Liang Y,Sun R,Huang S,Wang Z,Xiao L,Lu J,Yu H,Yao P
12-1171-82 was used in Flow cytometry/Cell sorting to conclude that HSCT can ameliorate maternal diabetes-mediated GI symptoms and autism-like behavior in mouse offspring.
Wed Jun 01 00:00:00 EDT 2022
Inaccessible LCG Promoters Act as Safeguards to Restrict T Cell Development to Appropriate Notch Signaling Environments.
Stem cell reports
Furuyama S,Wu QV,Varnum-Finney B,Sandstrom R,Meuleman W,Stamatoyannopoulos JA,Bernstein ID
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Jul 22 00:00:00 EDT 2021
SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis.
The Journal of biological chemistry
Cardenas RA,Gonzalez R,Sanchez E,Ramos MA,Cardenas EI,Rodarte AI,Alcazar-Felix RJ,Isaza A,Burns AR,Heidelberger R,Adachi R
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
mMCP7, a Mouse Ortholog of δ Tryptase, Mediates Pelvic Tactile Allodynia in a Model of Chronic Pelvic Pain.
Frontiers in pain research (Lausanne, Switzerland)
Pattabiraman G,Liu Z,Paul M,Schaeffer AJ,Thumbikat P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Oct 20 00:00:00 EDT 2023
Analysis of Radiation-Induced Changes in Cell Cycle and DNA Damage of Murine Hematopoietic Stem Cells by Multi-Color Flow Cytometry.
Current protocols
Majumdar D,Pietras EM,Pawar SA
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nature communications
Pennington LF,Gasser P,Kleinboelting S,Zhang C,Skiniotis G,Eggel A,Jardetzky TS
12-1171-82 was used in flow cytometry to show how kinetically active disruptive antibodies can be used to accelerate therapeutic efficacy, provide a structural and conceptual foundation for understanding disruptive antibody inhibition, and establish a pathway to engineering disruptive antibodies for other diseases.
Fri Dec 03 00:00:00 EST 2021
Ku80-Targeted pH-Sensitive Peptide-PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation.
Molecular cancer research : MCR
Kaplan AR,Pham H,Liu Y,Oyaghire S,Bahal R,Engelman DM,Glazer PM
12-1171 was used in Flow cytometry/Cell sorting to describes a novel agent, pHLIP-αKu80(γ), which combines PNA antisense and pHLIP technologies to selectively reduce the expression of the DNA repair factor KU80 in tumors and confer tumor-selective radiosensitization.
Mon Jun 01 00:00:00 EDT 2020
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.
Cell reports
van den Berk P,Lancini C,Company C,Serresi M,Sanchez-Bailon MP,Hulsman D,Pritchard C,Song JY,Schmitt MJ,Tanger E,Popp O,Mertins P,Huijbers IJ,Jacobs H,van Lohuizen M,Gargiulo G,Citterio E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2020
Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.
Biomedicines
Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Wed Dec 09 00:00:00 EST 2020
Type I Interferon α/β Receptor-Mediated Signaling Negatively Regulates Antiviral Cytokine Responses in Murine Bone-Marrow-Derived Mast Cells and Protects the Cells from Virus-Induced Cell Death.
International journal of molecular sciences
Darzianiazizi M,Mehrani Y,Chan L,Mould RC,Kulkarni RR,Sharif S,Bridle BW,Karimi K
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
JCI insight
Wang H,Georgakopoulou A,Li C,Liu Z,Gil S,Bashyam A,Yannaki E,Anagnostopoulos A,Pande A,Izsvák Z,Papayannopoulou T,Lieber A
12-1171 was used in Flow cytometry/Cell sorting to demonstrate that hematopoietic stem/progenitor cell (HSPC) mobilization followed by intravenous injection of integrating, helper-dependent adenovirus HDAd5/35++ vectors resulted in efficient transduction of long-term repopulating cells and disease amelioration in mouse models after in vivo selection of transduced HSPCs.
Thu Aug 20 00:00:00 EDT 2020
The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Nature communications
Gasser P,Tarchevskaya SS,Guntern P,Brigger D,Ruppli R,Zbären N,Kleinboelting S,Heusser C,Jardetzky TS,Eggel A
12-1171 was used in Flow cytometry/Cell sorting to investigate and compare the molecular binding profile and functional mechanisms of action of the anti-IgE antibody ligelizumab and omalizumab.
Wed Jan 08 00:00:00 EST 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
12-1171-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.
Cell stem cell
Ho YH,Del Toro R,Rivera-Torres J,Rak J,Korn C,García-García A,Macías D,González-Gómez C,Del Monte A,Wittner M,Waller AK,Foster HR,López-Otín C,Johnson RS,Nerlov C,Ghevaert C,Vainchenker W,Louache F,Andrés V,Méndez-Ferrer S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia.
Nature communications
Legrand JMD,Chan AL,La HM,Rossello FJ,Änkö ML,Fuller-Pace FV,Hobbs RM
12-1171-82 was used in Flow Cytometry to study the role of DDX5 in spermatogenesis.
Thu May 23 00:00:00 EDT 2019
Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.
Cell reports
Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC
12-1171 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.
Tue Mar 19 00:00:00 EDT 2019
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
12-1171 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias.
Genes & development
Kim SK,Knight DA,Jones LR,Vervoort S,Ng AP,Seymour JF,Bradner JE,Waibel M,Kats L,Johnstone RW
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation.
Stem cell reports
Hamanaka S,Umino A,Sato H,Hayama T,Yanagida A,Mizuno N,Kobayashi T,Kasai M,Suchy FP,Yamazaki S,Masaki H,Yamaguchi T,Nakauchi H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Oct 09 00:00:00 EDT 2018
Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis.
eLife
Bergiers I,Andrews T,Vargel Bölükbaşı Ö,Buness A,Janosz E,Lopez-Anguita N,Ganter K,Kosim K,Celen C,Itır Perçin G,Collier P,Baying B,Benes V,Hemberg M,Lancrin C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.
Nature communications
Yan J,Tie G,Wang S,Tutto A,DeMarco N,Khair L,Fazzio TG,Messina LM
12-1171 was used in Flow cytometry/Cell sorting to demonstrate for the first time that type 2 diabetes mellitus induces an haematopoietic stem cell-autonomous mechanism that causes impaired wound healing.
Tue Jan 02 00:00:00 EST 2018
In utero nanoparticle delivery for site-specific genome editing.
Nature communications
Ricciardi AS,Bahal R,Farrelly JS,Quijano E,Bianchi AH,Luks VL,Putman R,López-Giráldez F,Coşkun S,Song E,Liu Y,Hsieh WC,Ly DH,Stitelman DH,Glazer PM,Saltzman WM
12-1171 was used in Flow cytometry/Cell sorting to demonstrate the safe intravenous and intra-amniotic administration of polymeric nanoparticles to foetal mouse tissues at selected gestational ages with no effect on survival or postnatal growth.
Tue Jun 26 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Apr 06 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
12-1171 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.
Development (Cambridge, England)
Wu HJ,Oh JW,Spandau DF,Tholpady S,Diaz J,Schroeder LJ,Offutt CD,Glick AB,Plikus MV,Koyama S,Foley J
12-1171 was used in Flow cytometry/Cell sorting to show that specialized nipple epidermis is maintained by estrogen-induced repression of TGFβ signalling in the local fibroblasts.
Sat Apr 15 00:00:00 EDT 2017
Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.
Scientific reports
Alzubi J,Pallant C,Mussolino C,Howe SJ,Thrasher AJ,Cathomen T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Sep 29 00:00:00 EDT 2017
Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.
Scientific reports
Nakamura Y,Ishimaru K,Shibata S,Nakao A
12-1171 was used in Flow cytometry/Cell sorting to determine how steady-state plasma histamine levels are regulated and affected by environmental factors.
Wed Jan 11 00:00:00 EST 2017
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
12-1171 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 EDT 2017
Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis.
The Journal of clinical investigation
Gu H,Chen C,Hao X,Wang C,Zhang X,Li Z,Shao H,Zeng H,Yu Z,Xie L,Xia F,Zhang F,Liu X,Zhang Y,Jiang H,Zhu J,Wan J,Wang C,Weng W,Xie J,Tao M,Zhang CC,Liu J,Chen GQ,Zheng J
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
12-1171 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Fibrillin-1 microfibrils influence adult bone marrow hematopoiesis.
Matrix biology : journal of the International Society for Matrix Biology
Smaldone S,Bigarella CL,Del Solar M,Ghaffari S,Ramirez F
12-1171 was used in Flow cytometry/Cell sorting to investigate adult haematopoiesis in mice with Cre-mediated inactivation of the fibrillin-1 gene in the mesenchyme of the forming limbs.
Wed Dec 20 00:00:00 EST 2017
Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile.
Arthritis research & therapy
van der Velden D,Lagraauw HM,Wezel A,Launay P,Kuiper J,Huizinga TW,Toes RE,Bot I,Stoop JN
12-1171 was used in Flow cytometry/Cell sorting to suggest that mast cells may play a role in the regulation of the adaptive immune response during the development of arthritis.
Mon Jun 13 00:00:00 EDT 2016
Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration.
American journal of physiology. Heart and circulatory physiology
Bellio MA,Rodrigues CO,Landin AM,Hatzistergos KE,Kuznetsov J,Florea V,Valasaki K,Khan A,Hare JM,Schulman IH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.
Molecular and cellular biology
Thoms JA,Knezevic K,Liu JJ,Glaros EN,Thai T,Qiao Q,Campbell H,Packham D,Huang Y,Papathanasiou P,Tunningley R,Whittle B,Yeung AW,Chandrakanthan V,Hesson L,Chen V,Wong JW,Purton LE,Ward RL,Thomas SR,Pimanda JE
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo.
Stem cell reports
Crisan M,Solaimani Kartalaei P,Neagu A,Karkanpouna S,Yamada-Inagawa T,Purini C,Vink CS,van der Linden R,van Ijcken W,Chuva de Sousa Lopes SM,Monteiro R,Mummery C,Dzierzak E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
12-1171 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal.
Nature
Acar M,Kocherlakota KS,Murphy MM,Peyer JG,Oguro H,Inra CN,Jaiyeola C,Zhao Z,Luby-Phelps K,Morrison SJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circulation research
Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M
12-1171 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.
Fri Oct 23 00:00:00 EDT 2015
Mast cells mediate malignant pleural effusion formation.
The Journal of clinical investigation
Giannou AD,Marazioti A,Spella M,Kanellakis NI,Apostolopoulou H,Psallidas I,Prijovich ZM,Vreka M,Zazara DE,Lilis I,Papaleonidopoulos V,Kairi CA,Patmanidi AL,Giopanou I,Spiropoulou N,Harokopos V,Aidinis V,Spyratos D,Teliousi S,Papadaki H,Taraviras S,Snyder LA,Eickelberg O,Kardamakis D,Iwakura Y,Feyerabend TB,Rodewald HR,Kalomenidis I,Blackwell TS,Agalioti T,Stathopoulos GT
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Hematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway.
The Journal of experimental medicine
Tesio M,Tang Y,Müdder K,Saini M,von Paleske L,Macintyre E,Pasparakis M,Waisman A,Trumpp A
12-1171 was used in Flow cytometry/Cell sorting to elucidate the molecular mechanisms regulating haematopoietic stem cell dormancy.
Mon Apr 06 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.
EMBO reports
Hobbs RM,La HM,Mäkelä JA,Kobayashi T,Noda T,Pandolfi PP
12-1171 was used in Flow cytometry/Cell sorting to propose that mTORC1 is a key regulator of SPC fate and defines phenotypically distinct SPC subpopulations for self-renewal and differentiation.
Wed Apr 01 00:00:00 EDT 2015
Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth.
Mucosal immunology
Shiu J,Piazuelo MB,Ding H,Czinn SJ,Drakes ML,Banerjee A,Basappa N,Kobayashi KS,Fricke WF,Blanchard TG
12-1171 was used in Flow cytometry/Cell sorting to investigate the role of lymphoid tissue inducer cells in the gastric mucosa in the context of microbial infection.
Tue Sep 01 00:00:00 EDT 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
12-1171 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation.
PloS one
Zoch A,Mayerl S,Schulz A,Greither T,Frappart L,Rübsam J,Heuer H,Giovannini M,Morrison H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon May 23 00:00:00 EDT 2016
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
Nature medicine
Bruns I,Lucas D,Pinho S,Ahmed J,Lambert MP,Kunisaki Y,Scheiermann C,Schiff L,Poncz M,Bergman A,Frenette PS
12-1171 was used in Flow cytometry/Cell sorting to indicate that a terminally differentiated cell type derived from HSCs contributes to the HSC niche, directly regulating HSC behavior.
Sat Nov 01 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Genome medicine
Sonnet M,Claus R,Becker N,Zucknick M,Petersen J,Lipka DB,Oakes CC,Andrulis M,Lier A,Milsom MD,Witte T,Gu L,Kim-Wanner SZ,Schirmacher P,Wulfert M,Gattermann N,Lübbert M,Rosenbauer F,Rehli M,Bullinger L,Weichenhan D,Plass C
12-1171 was used in Flow cytometry/Cell sorting to investigate the onset of aberrant DNA methylation events and their dynamics during leukemic progression.
Thu Jun 19 00:00:00 EDT 2014
Pharmacological mobilization of endogenous stem cells significantly promotes skin regeneration after full-thickness excision: the synergistic activity of AMD3100 and tacrolimus.
The Journal of investigative dermatology
Lin Q,Wesson RN,Maeda H,Wang Y,Cui Z,Liu JO,Cameron AM,Gao B,Montgomery RA,Williams GM,Sun Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.
Development (Cambridge, England)
Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun Jun 01 00:00:00 EDT 2014
IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.
Journal of immunology (Baltimore, Md. : 1950)
Shibata K,Yamada H,Nakamura M,Hatano S,Katsuragi Y,Kominami R,Yoshikai Y
12-1171 was used in Flow cytometry/Cell sorting to compare the functions of γδ T cells derived from double-negative 2 and double-negative 3 cells in the murine fetal thymus.
Sat Mar 01 00:00:00 EST 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.
Molecular & cellular proteomics : MCP
Honarpour N,Rose CM,Brumbaugh J,Anderson J,Graham RL,Sweredoski MJ,Hess S,Coon JJ,Deshaies RJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Regulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cells.
PloS one
Zhu J,Bi Z,Yang T,Wang W,Li Z,Huang W,Wang L,Zhang S,Zhou Y,Fan N,Bai Y,Song W,Wang C,Wang H,Bi Y
12-1171 was used in Flow cytometry/Cell sorting to investigate regulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cells.
Tue Sep 15 00:00:00 EDT 2015
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
12-1171 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
The Journal of experimental medicine
Gao X,Johnson KD,Chang YI,Boyer ME,Dewey CN,Zhang J,Bresnick EH
12-1171 was used in Flow cytometry/Cell sorting to investigate the role of Gata2 cis-element in generation of hematopoietic stem cells.
Mon Dec 16 00:00:00 EST 2013
Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization.
The Journal of experimental medicine
Tesio M,Oser GM,Baccelli I,Blanco-Bose W,Wu H,Göthert JR,Kogan SC,Trumpp A
12-1171 was used in Flow cytometry/Cell sorting to investigate the effect of PTEN deletion in bone marrow, showing that it leads to G-CSF-mediated hematopoietic stem cell mobilisation.
Mon Oct 21 00:00:00 EDT 2013
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
12-1171 was used in Flow cytometry/Cell sorting to show that macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentum.
Tue Jan 01 00:00:00 EST 2013
Sca1-derived cells are a source of myocardial renewal in the murine adult heart.
Stem cell reports
Uchida S,De Gaspari P,Kostin S,Jenniches K,Kilic A,Izumiya Y,Shiojima I,Grosse Kreymborg K,Renz H,Walsh K,Braun T
12-1171 was used in Flow cytometry/Cell sorting to reveal a source of cells for cardiomyocyte renewal, providing explanation for the limited contribution of Sca1-derived cells to myocardial repair.
Mon Oct 26 00:00:00 EDT 2015
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
A non-redundant function of cyclin E1 in hematopoietic stem cells.
Cell cycle (Georgetown, Tex.)
Campaner S,Viale A,De Fazio S,Doni M,De Franco F,D'Artista L,Sardella D,Pelicci PG,Amati B
12-1171 was used in Flow cytometry/Cell sorting to support a role for cyclin E1 in controlling the exit from quiescence in hematopoietic stem cells.
Sun Dec 01 00:00:00 EST 2013
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
12-1171 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 EST 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
12-1171-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells.
Molecular & cellular proteomics : MCP
Klimmeck D,Hansson J,Raffel S,Vakhrushev SY,Trumpp A,Krijgsveld J
12-1171 was used in Flow cytometry/Cell sorting to discern the distinct signatures of multipotent progenitors and myeloid committed cells.
Wed Aug 01 00:00:00 EDT 2012
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature
Zuber J,Shi J,Wang E,Rappaport AR,Herrmann H,Sison EA,Magoon D,Qi J,Blatt K,Wunderlich M,Taylor MJ,Johns C,Chicas A,Mulloy JC,Kogan SC,Brown P,Valent P,Bradner JE,Lowe SW,Vakoc CR
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Wed Aug 03 00:00:00 EDT 2011
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
Nature immunology
Monticelli LA,Sonnenberg GF,Abt MC,Alenghat T,Ziegler CG,Doering TA,Angelosanto JM,Laidlaw BJ,Yang CY,Sathaliyawala T,Kubota M,Turner D,Diamond JM,Goldrath AW,Farber DL,Collman RG,Wherry EJ,Artis D
12-1171 was used in Flow cytometry/Cell sorting to demonstrate a critical role for lung ILCs in restoring airway epithelial integrity and tissue homeostasis after viral replication.
Tue Nov 01 00:00:00 EDT 2011
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
Blood
Cook BD,Liu S,Evans T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Thu Jun 16 00:00:00 EDT 2011
The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice.
European journal of immunology
Fuchiwaki T,Sun X,Fujimura K,Yamada H,Shibata K,Muta H,Podack ER,Kawauchi H,Yoshikai Y
12-1171 was used in Flow cytometry/Cell sorting to examine the role of CD30 ligand in allergic rhinitis.
Sat Oct 01 00:00:00 EDT 2011
Identification of a novel antigen cross-presenting cell type in spleen.
Journal of cellular and molecular medicine
Tan JK,Quah BJ,Griffiths KL,Periasamy P,Hey YY,O'Neill HC
12-1171 was used in Flow cytometry/Cell sorting to study a novel DC type produced by in vitro haematopoiesis which has distinct antigen-presenting potential and reflects a DC subset present also in vivo in spleen.
Sun May 01 00:00:00 EDT 2011
Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair.
American journal of physiology. Heart and circulatory physiology
Zisa D,Shabbir A,Mastri M,Taylor T,Aleksic I,McDaniel M,Suzuki G,Lee T
12-1171 was used in Flow cytometry/Cell sorting to investigate two distinct but synergistic cardiac therapeutic mechanisms activated by intramuscular VEGF.
Thu Dec 01 00:00:00 EST 2011
Sox3 functions in a cell-autonomous manner to regulate spermatogonial differentiation in mice.
Endocrinology
Laronda MM,Jameson JL
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2011
Contribution of IL-13 to early exocrinopathy in Id3-/- mice.
Molecular immunology
Mahlios J,Zhuang Y
12-1171 was used in Immunofluorescence to examine the role of cytokines produced by T cells in the systemic regulation of salivary gland function.
Sat Oct 01 00:00:00 EDT 2011
Ultrastructural features and possible functional role of kit-positive interstitial cells in the guinea pig corpus cavernosum.
International journal of impotence research
Fu W,Song B,Li W,Shen W,Ji H,Wang Y,Zhen J,Zhou Z,Yan J
12-1171 was used in Flow cytometry/Cell sorting to imply that interstitial cells express nitric oxide-sensitive soluble guanylate cyclase and which may be involved relaxation of corpus cavernosum smooth muscle.
Tue Nov 08 00:00:00 EST 2011
Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells.
Cytotechnology
Kawahara T,Iizuka T
12-1171 was used in Flow cytometry/Cell sorting to suggest that a crude hot-water extract of quince inhibits mast cell function during type 1 allergic reactions by suppressing inflammatory cytokine expression and lipid mediator production.
Tue Mar 01 00:00:00 EST 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Fine-scale staging of T cell lineage commitment in adult mouse thymus.
Journal of immunology (Baltimore, Md. : 1950)
Yui MA,Feng N,Rothenberg EV
12-1171 was used in Flow cytometry/Cell sorting to determine the gene regulatory changes that accompany commitment in adult wild-type double-negative adult thymocytes.
Thu Jul 01 00:00:00 EDT 2010
Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen.
American journal of physiology. Heart and circulatory physiology
Shabbir A,Zisa D,Suzuki G,Lee T
12-1171 was used in Flow cytometry/Cell sorting to highlight a noninvasive cardiac repair mechanism mediated by injected MSCs.
Mon Jun 01 00:00:00 EDT 2009
Intramuscular VEGF repairs the failing heart: role of host-derived growth factors and mobilization of progenitor cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Zisa D,Shabbir A,Mastri M,Suzuki G,Lee T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2009
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation.
The Journal of experimental medicine
Besseyrias V,Fiorini E,Strobl LJ,Zimber-Strobl U,Dumortier A,Koch U,Arcangeli ML,Ezine S,Macdonald HR,Radtke F
12-1171 was used in Flow cytometry/Cell sorting to study the Notch-Delta interactions that promote T cell development.
Mon Feb 19 00:00:00 EST 2007
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
12-1171-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells.
Journal of immunology (Baltimore, Md. : 1950)
Chen Y,Pappu BP,Zeng H,Xue L,Morris SW,Lin X,Wen R,Wang D
12-1171-82 was used in Flow cytometry/Cell sorting to conclude that Bcl10 is essential for FcepsilonR-induced activation of AP-1, NF-kappaB, degranulation, and cytokine production in mast cells.
Mon Jan 01 00:00:00 EST 2007
Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk.
Blood
Takizawa H,Kubo-Akashi C,Nobuhisa I,Kwon SM,Iseki M,Taga T,Takatsu K,Takaki S
12-1171 was used in Flow cytometry/Cell sorting to investigate the potential of Lnk for augmented engraftment of HSCs.
Sat Apr 01 00:00:00 EST 2006
Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.
Molecular and cellular biology
Wen R,Chen Y,Bai L,Fu G,Schuman J,Dai X,Zeng H,Yang C,Stephan RP,Cleveland JL,Wang D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 12-1171-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006
T/B lineage choice occurs prior to intrathymic Notch signaling.
Blood
Harman BC,Jenkinson WE,Parnell SM,Rossi SW,Jenkinson EJ,Anderson G
12-1171 was used in Flow cytometry/Cell sorting to analyse the T-cell/B-cell lineage potential of precursors that have been recruited to the foetal mouse thymus, showing that lineage choice occurs prior to intrathymic Notch signaling.
Mon Aug 01 00:00:00 EDT 2005
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.jpg?time=20240507?time=20240507 "CD117 (c-Kit) Antibody (12-1171-82) in Flow")
