Product References
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
International journal of nanomedicine
Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
The Cxcr2+ subset of the S100a8+ gastric granylocytic myeloid-derived suppressor cell population (G-MDSC) regulates gastric pathology.
Frontiers in immunology
Kao KD,Grasberger H,El-Zaatari M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Sep 29 00:00:00 EDT 2023
LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.
Journal for immunotherapy of cancer
Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.
Journal of experimental & clinical cancer research : CR
Zheng Y,Wang N,Wang S,Zhang J,Yang B,Wang Z
14-0112-82 was used in Immunohistochemistry-immunofluorescence to investigate the impact of chronic psychological stress on breast cancer growth, metastasis, and pre-metastatic niche (PMN) formation.
Sat May 20 00:00:00 EDT 2023
Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation, and neutrophil functions.
Frontiers in immunology
Rizvi ZA,Babele P,Madan U,Sadhu S,Tripathy MR,Goswami S,Mani S,Dikshit M,Awasthi A
14-0112-82 was used in In vitro Assay to demonstrate a robust protective effect of WS against COVID-19 through its broader immunomodulatory activity.
Mon Mar 27 00:00:00 EDT 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Feb 21 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma.
Acta pharmaceutica Sinica. B
Tan J,Liu T,Fan W,Wei J,Zhu B,Liu Y,Liu L,Zhang X,Chen S,Lin H,Zhang Y,Li J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.
Materials today. Bio
Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.
Cancers
Spella M,Ntaliarda G,Skiadas G,Lamort AS,Vreka M,Marazioti A,Lilis I,Bouloukou E,Giotopoulou GA,Pepe MAA,Weiss SAI,Petrera A,Hauck SM,Koch I,Lindner M,Hatz RA,Behr J,Arendt KAM,Giopanou I,Brunn D,Savai R,Jenne DE,de Château M,Yull FE,Blackwell TS,Stathopoulos GT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Mar 20 00:00:00 EDT 2023
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development.
Cancer nanotechnology
Sun W,Dai L,Cao Y,Pan P,Zhi L,Wang X,Yuan X,Gao Z,Guo S,Liu G,Yin J,Xie L,Wang L,Wang Y,Li W,Li H,Jia Y
14-0112-82 was used in Flow cytometry/Cell sorting to provide novel vaccination strategy for the development of tumor vaccines and facilitate the application of T-MPs for clinic oncotherapy.
Tue Apr 25 00:00:00 EDT 2023
The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis.
PeerJ
Li JL,Fu GQ,Wang YY,Bian MM,Xu YM,Zhang L,Chen YQ,Zhang N,Ding SQ,Wang R,Fang R,Tang J,Hu JG,Lü HZ
14-0112-82 was used in Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization to study if M1 cells in injured spinal cords were mainly derived from MG rather than infiltrating Mø.
Tue Feb 28 00:00:00 EST 2023
Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment.
Experimental & molecular medicine
Seo SH,Kim E,Yoon M,Lee SH,Park BH,Choi KY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2022
Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis.
Nature communications
Dai B,Xu J,Li X,Huang L,Hopkins C,Wang H,Yao H,Mi J,Zheng L,Wang J,Tong W,Chow DH,Li Y,He X,Hu P,Chen Z,Zu H,Li Y,Yao Y,Jiang Q,Qin L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jan 20 00:00:00 EST 2022
PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.
Nature communications
Schmid MC,Kang SW,Chen H,Paradise M,Ghebremedhin A,Kaneda MM,Chin SM,Do A,Watterson DM,Varner JA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.
PLoS neglected tropical diseases
Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells.
Cells
Le-Bel G,Desjardins P,Gross C,Cortez Ghio S,Couture C,Germain L,Guérin SL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Western Blot
Wed Aug 31 00:00:00 EDT 2022
TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target.
Biology
Palacios LM,Peyret V,Viano ME,Geysels RC,Chocobar YA,Volpini X,Pellizas CG,Nicola JP,Motran CC,Rodriguez-Galan MC,Fozzatti L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 03 00:00:00 EDT 2022
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Feb 02 00:00:00 EST 2023
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.
Nature communications
Franklin R,Guo Y,He S,Chen M,Ji F,Zhou X,Frankhouser D,Do BT,Chiem C,Jang M,Blanco MA,Vander Heiden MG,Rockne RC,Ninova M,Sykes DB,Hochedlinger K,Lu R,Sadreyev RI,Murn J,Volk A,Cheloufi S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 29 00:00:00 EDT 2022
Biocompatible reduced graphene oxide stimulated BMSCs induce acceleration of bone remodeling and orthodontic tooth movement through promotion on osteoclastogenesis and angiogenesis.
Bioactive materials
Jiao D,Wang J,Yu W,Zhang K,Zhang N,Cao L,Jiang X,Bai Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2022
Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
International journal of molecular sciences
Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Feb 23 00:00:00 EST 2022
Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
International journal of molecular sciences
Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Feb 23 00:00:00 EST 2022
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension.
British journal of pharmacology
Wang L,Zhang X,Cao Y,Ma Q,Mao X,Xu J,Yang Q,Zhou Y,Lucas R,Fulton DJ,Su Y,Barman SA,Hong M,Liu Z,Huo Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.
Diabetes
Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
CD36 deficiency ameliorates drug-induced acute liver injury in mice.
Molecular medicine (Cambridge, Mass.)
Zhang C,Shi X,Su Z,Hu C,Mu X,Pan J,Li M,Teng F,Ling T,Zhao T,Xu C,Ji G,You Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Jun 06 00:00:00 EDT 2021
Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Man K,Chen Z
14-0112-82 was used in Flow Cytometry to evaluate the potential of recombinant adeno-associated virus (rAAV)-vectored, PD1-based vaccination in the tumor microenvironment (TME) to activate antigen-specific T cell responses in the immune-competent murine mesothelioma model.
Fri Mar 26 00:00:00 EDT 2021
VX-765 reduces neuroinflammation after spinal cord injury in mice.
Neural regeneration research
Chen J,Chen YQ,Shi YJ,Ding SQ,Shen L,Wang R,Wang QY,Zha C,Ding H,Hu JG,Lü HZ
14-0112-82 was used in Immunohistochemistry to suggest that VX-765 can reduce neuroinflammation and improve nerve function recovery after spinal cord injury by inhibiting caspase-1/interleukin-1β/interleukin-18.
Wed Sep 01 00:00:00 EDT 2021
Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice.
Investigative ophthalmology & visual science
Clarkson-Townsend DA,Bales KL,Marsit CJ,Pardue MT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Apr 01 00:00:00 EDT 2021
Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice.
Investigative ophthalmology & visual science
Clarkson-Townsend DA,Bales KL,Marsit CJ,Pardue MT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Apr 01 00:00:00 EDT 2021
Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice.
The Journal of reproduction and development
Hirata Y,Katsukura Y,Henmi Y,Ozawa R,Shimazaki S,Kurosawa A,Torii Y,Takahashi H,Iwata H,Kuwayama T,Shirasuna K
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Aug 27 00:00:00 EDT 2021
Effect of IL-33 on pyroptosis of macrophages in mice with sepsis via NF-κB/p38 MAPK signaling pathway.
Acta cirurgica brasileira
Ke J,Cai G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Fri Jun 18 00:00:00 EDT 2021
Effect of IL-33 on pyroptosis of macrophages in mice with sepsis via NF-κB/p38 MAPK signaling pathway.
Acta cirurgica brasileira
Ke J,Cai G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Fri Jun 18 00:00:00 EDT 2021
Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.
Cellular and molecular gastroenterology and hepatology
Zhang X,Liu X,Zhou W,Du Q,Yang M,Ding Y,Hu R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Fri Mar 25 00:00:00 EDT 2022
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Nov 15 00:00:00 EST 2021
Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.
Biology
Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (Frozen)
Thu May 27 00:00:00 EDT 2021
Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.
Biology
Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (Frozen)
Thu May 27 00:00:00 EDT 2021
Dual Activity of Ginsenoside Rb1 in Hypertrophic Cardiomyocytes and Activated Macrophages: Implications for the Therapeutic Intervention of Cardiac Hypertrophy.
Journal of inflammation research
Wang S,Cui Y,Xiong M,Li M,Wang P,Cui J,Du X,Chen Y,Zhang T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Sat Apr 23 00:00:00 EDT 2022
Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.
Frontiers in pharmacology
Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Apr 02 00:00:00 EDT 2022
Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression.
Bioengineered
Xin Y,Song X,Ge Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Western Blot
Wed Dec 01 00:00:00 EST 2021
Mycobacterium tuberculosis Load in Host Cells and the Antibacterial Activity of Alveolar Macrophages Are Linked and Differentially Regulated in Various Lung Lesions of Patients with Pulmonary Tuberculosis.
International journal of molecular sciences
Ufimtseva EG,Eremeeva NI,Umpeleva TV,Vakhrusheva DV,Skornyakov SN
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Mar 26 00:00:00 EDT 2021
Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.
Frontiers in cardiovascular medicine
Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Fri May 20 00:00:00 EDT 2022
Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.
Frontiers in cardiovascular medicine
Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Fri May 20 00:00:00 EDT 2022
Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.
Frontiers in cardiovascular medicine
Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Fri May 20 00:00:00 EDT 2022
Developmental chronodisruption alters placental signaling in mice.
PloS one
Clarkson-Townsend DA,Bales KL,Hermetz KE,Burt AA,Pardue MT,Marsit CJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Wed Nov 24 00:00:00 EST 2021
Developmental chronodisruption alters placental signaling in mice.
PloS one
Clarkson-Townsend DA,Bales KL,Hermetz KE,Burt AA,Pardue MT,Marsit CJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Wed Nov 24 00:00:00 EST 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.
Frontiers in immunology
Alam J,de Paiva CS,Pflugfelder SC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
A Population of M2 Macrophages Associated With Bone Formation.
Frontiers in immunology
Olmsted-Davis E,Mejia J,Salisbury E,Gugala Z,Davis AR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Dec 13 00:00:00 EST 2021
Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.
JCI insight
Hu X,Dong X,Li G,Chen Y,Chen J,He X,Sun H,Kim DH,Kemper JK,Chen LF
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jul 21 00:00:00 EDT 2021
Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Nature communications
Fujino T,Goyama S,Sugiura Y,Inoue D,Asada S,Yamasaki S,Matsumoto A,Yamaguchi K,Isobe Y,Tsuchiya A,Shikata S,Sato N,Morinaga H,Fukuyama T,Tanaka Y,Fukushima T,Takeda R,Yamamoto K,Honda H,Nishimura EK,Furukawa Y,Shibata T,Abdel-Wahab O,Suematsu M,Kitamura T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Mar 23 00:00:00 EDT 2021
M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors.
Journal of nanobiotechnology
Wang Y,Gong X,Li J,Wang H,Xu X,Wu Y,Wang J,Wang S,Li Y,Zhang Z
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Neutralization
Sat Nov 27 00:00:00 EST 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse.
STAR protocols
Zeng W,Yin X,Jiang Y,Jin L,Liang W
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tan H,Song Y,Chen J,Zhang N,Wang Q,Li Q,Gao J,Yang H,Dong Z,Weng X,Wang Z,Sun D,Yakufu W,Pang Z,Huang Z,Ge J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.
Journal of neuroinflammation
MacLean M,Juranek J,Cuddapah S,López-Díez R,Ruiz HH,Hu J,Frye L,Li H,Gugger PF,Schmidt AM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Tue Jun 15 00:00:00 EDT 2021
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.
Journal of neuroinflammation
MacLean M,Juranek J,Cuddapah S,López-Díez R,Ruiz HH,Hu J,Frye L,Li H,Gugger PF,Schmidt AM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Tue Jun 15 00:00:00 EDT 2021
Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint.
Cells
Nazet U,Feulner L,Muschter D,Neubert P,Schatz V,Grässel S,Jantsch J,Proff P,Schröder A,Kirschneck C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Feb 18 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment.
iScience
Fu H,Gui Y,Liu S,Wang Y,Bastacky SI,Qiao Y,Zhang R,Bonin C,Hargis G,Yu Y,Kreutzer DL,Biswas PS,Zhou Y,Wang Y,Tian XJ,Liu Y,Zhou D
14-0112-82 was used in Flow Cytometry to validate that loss of c-met influences epithelial plasticity, myofibroblast activation, and extracellular matrix synthesis/degradation, which ultimately determined the characteristics of the fibrotic KLM.
Fri Oct 22 00:00:00 EDT 2021
Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice.
Physiological reports
Miura I,Komine S,Okada K,Wada S,Warabi E,Uchida F,Oh S,Suzuki H,Mizokami Y,Shoda J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
14-0112-82 was used in Immunocytochemistry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 EDT 2021
Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.
Cell reports
Dang MT,Gonzalez MV,Gaonkar KS,Rathi KS,Young P,Arif S,Zhai L,Alam Z,Devalaraja S,To TKJ,Folkert IW,Raman P,Rokita JL,Martinez D,Taroni JN,Shapiro JA,Greene CS,Savonen C,Mafra F,Hakonarson H,Curran T,Haldar M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Mar 30 00:00:00 EDT 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Inflammation-induced alterations in maternal-fetal Heme Oxygenase (HO) are associated with sustained innate immune cell dysregulation in mouse offspring.
PloS one
Ozen M,Zhao H,Kalish F,Yang Y,Jantzie LL,Wong RJ,Stevenson DK
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Nov 17 00:00:00 EST 2021
Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells.
Nature
Zhang B,Ma S,Rachmin I,He M,Baral P,Choi S,Gonçalves WA,Shwartz Y,Fast EM,Su Y,Zon LI,Regev A,Buenrostro JD,Cunha TM,Chiu IM,Fisher DE,Hsu YC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Jan 01 00:00:00 EST 2020
Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells.
Nature
Zhang B,Ma S,Rachmin I,He M,Baral P,Choi S,Gonçalves WA,Shwartz Y,Fast EM,Su Y,Zon LI,Regev A,Buenrostro JD,Cunha TM,Chiu IM,Fisher DE,Hsu YC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Jan 01 00:00:00 EST 2020
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Cell research
Wang S,Qu Y,Xia P,Chen Y,Zhu X,Zhang J,Wang G,Tian Y,Ying J,Fan Z
14-0112-82 was used in Flow Cytometry to profile tumor infiltrating innate lymphoid cells in colorectal cancer at early and late stages.
Wed Jul 01 00:00:00 EDT 2020
Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.
Nano-micro letters
Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Nov 21 00:00:00 EST 2020
B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection.
The Journal of experimental medicine
Arroyo EN,Pepper M
14-0112-82 was used in Flow Cytometry to study antigen-specific CD4+ T follicular helper (Tfh) cells responding to Plasmodium infection in order to understand the generation and maintenance of the Tfh response.
Mon Feb 03 00:00:00 EST 2020
LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
The EMBO journal
Liu Z,Xu E,Zhao HT,Cole T,West AB
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
The EMBO journal
Liu Z,Xu E,Zhao HT,Cole T,West AB
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
14-0112-82 was used in Flow Cytometry to report a feature of skin Treg cells expanded by ultraviolet B (UVB) exposure.
Tue Aug 25 00:00:00 EDT 2020
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy.
Basic research in cardiology
Lubos N,van der Gaag S,Gerçek M,Kant S,Leube RE,Krusche CA
14-0112 was used in Immunohistochemistry to investigate if specific immune cell populations and chemokine expression profiles modulate inflammatory and repair processes throughout arrhythmogenic cardiomyopathy progression.
Fri Jun 12 00:00:00 EDT 2020
Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Arteriosclerosis, thrombosis, and vascular biology
Chapouly C,Hollier PL,Guimbal S,Cornuault L,Gadeau AP,Renault MA
14-0112-86 was used in Immunocytochemistry to investigate whether hedgehog coreceptors Gas1 (growth arrest-specific 1) and Cdon (cell adhesion molecule-related/downregulated by oncogenes) may be used as therapeutic targets to modulate Dhh signaling in ECs.
Tue Dec 01 00:00:00 EST 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn's Disease.
Journal of Crohn's & colitis
Gong W,Zheng T,Guo K,Fang M,Xie H,Li W,Tang Q,Hong Z,Ren H,Gu G,Wang G,Wu X,Zhao Y,Ren J
14-0112 was used in Flow cytometry/Cell sorting to show that Mincle signaling is significantly elevated in active human CD and experimental colitis, and macrophages are the principal leukocyte subset that up-regulate Mincle signaling.
Wed Dec 02 00:00:00 EST 2020
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.
PLoS biology
Li J,Zhao Y,Choi J,Ting KK,Coleman P,Chen J,Cogger VC,Wan L,Shi Z,Moller T,Zheng X,Vadas MA,Gamble JR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Mon Jun 01 00:00:00 EDT 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.
Mucosal immunology
Wang C,Li Q,Lv J,Sun X,Cao Y,Yu K,Miao C,Zhang ZS,Yao Z,Wang Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.
Glia
Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury.
The American journal of pathology
Baluk P,Naikawadi RP,Kim S,Rodriguez F,Choi D,Hong YK,Wolters PJ,McDonald DM
14-0112-82 was used in Immunohistochemistry to suggest that lymphatics have an overall protective effect in lung injury and fibrosis and fit with a mechanism whereby lung lymphatic network expansion reduces lymph stasis and increases clearance of fluid and cells, including profibrotic macrophages.
Tue Dec 01 00:00:00 EST 2020
Vitronectin mitigates stroke-increased neurogenesis only in female mice and through FAK-regulated IL-6.
Experimental neurology
Jia C,Keasey MP,Malone HM,Lovins C,Hagg T
14-0112-82 was used in Immunohistochemistry (Frozen) to study the role of vitronectin (VTN) in response to ischaemic stroke in adult mice.
Wed Jan 01 00:00:00 EST 2020
T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
Journal of immunology (Baltimore, Md. : 1950)
Bonami RH,Nyhoff LE,McNitt DH,Hulbert C,Felton JL,Kendall PL,Thomas JW
14-0112-82 was used in Flow Cytometry to understand how fully developed T follicular helper cells contribute to different autoimmune processes, investigating the role of signaling lymphocytic activation molecule-associated protein in type 1 diabetes and autoantibody-mediated arthritis.
Tue Dec 15 00:00:00 EST 2020
Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Journal of immunology (Baltimore, Md. : 1950)
Ogden HL,Lai Y,Nolin JD,An D,Frevert CW,Gelb MH,Altemeier WA,Hallstrand TS
14-0112-82 was used in Flow Cytometry to demonstrate that exogenous and endogenous sPLA2s play an important role in peripheral sensitization, resulting in airway responses to inhaled Ags.
Mon Jun 15 00:00:00 EDT 2020
Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea.
Investigative ophthalmology & visual science
Díaz NM,Lang RA,Van Gelder RN,Buhr ED
14-0112 was used in Immunohistochemistry to demonstrate that opsin-dependent direct light sensitivity can be facultatively induced in the murine cornea.
Wed Jun 03 00:00:00 EDT 2020
Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity.
Journal of immunology research
Antonucci L,Porcu C,Timperi E,Santini SJ,Iannucci G,Balsano C
14-0112 was used in Flow cytometry/Cell sorting to evaluate the frequency of PolyMorphonuclear Neutrophils in NAFL and NASH patients in order to understand how they modulate the activity of circulating cells.
Fri May 21 00:00:00 EDT 2021
Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics.
Molecular medicine reports
Wang B,Wang L,Mao J,Wen H,Xu L,Ren Y,Du H,Yang H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Journal of cardiovascular pharmacology
Jia K,Dai Y,Liu A,Li X,Wu L,Lu L,Bao Y,Jin Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.
Cancers
Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.
Cancers
Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.
Cancers
Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma.
Cancers
Shirley SA,Lundberg CG,Heller R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Oct 21 00:00:00 EDT 2020
Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma.
Cancers
Shirley SA,Lundberg CG,Heller R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Oct 21 00:00:00 EDT 2020
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues.
Cells
Iannotta L,Biosa A,Kluss JH,Tombesi G,Kaganovich A,Cogo S,Plotegher N,Civiero L,Lobbestael E,Baekelandt V,Cookson MR,Greggio E
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Thu Oct 22 00:00:00 EDT 2020
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues.
Cells
Iannotta L,Biosa A,Kluss JH,Tombesi G,Kaganovich A,Cogo S,Plotegher N,Civiero L,Lobbestael E,Baekelandt V,Cookson MR,Greggio E
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry (PFA fixed)
Thu Oct 22 00:00:00 EDT 2020
The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.
Cell death & disease
Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2020
The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.
Cell death & disease
Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2020
Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.
Cell death & disease
Zheng Z,Jia S,Shao C,Shi Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2020
Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.
Frontiers in immunology
Hsu CY,Lin YC,Chang LY,Huang SK,Huang CH,Yang CK,Huang CT,Lin CY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
Differential Activation of Macrophages Based on Their Environment in Advanced Age.
Chonnam medical journal
Lee DY,Lim JS,Cho KA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration.
eLife
Baba T,Miyazaki D,Inata K,Uotani R,Miyake H,Sasaki SI,Shimizu Y,Inoue Y,Nakamura K
14-0112 was used in Immunohistochemistry to determine the functional role of IL-4 in CNV formation using murine choroidal neovascularization model.
Tue May 05 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment.
Journal of neuroinflammation
Chen YQ,Wang SN,Shi YJ,Chen J,Ding SQ,Tang J,Shen L,Wang R,Ding H,Hu JG,Lü HZ
14-0112-86 was used in Immunohistochemistry (Frozen) to study the effect of CRID3 on the local microenvironment and the possible role in neuroprotection following spinal cord injury.
Sat Aug 29 00:00:00 EDT 2020
Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.
Frontiers in immunology
Chandran S,Schilke RM,Blackburn CMR,Yurochko A,Mirza R,Scott RS,Finck BN,Woolard MD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
14-0112 was used in Magnetic cell separation to suggest that chronic inflammation induced by CCL2 significantly enhances tumor growth and promotes the formation of a desmoplastic stroma through early recruitment of macrophages and fibrocytes into the tumor microenvironment.
Tue Jul 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
14-0112 was used in Magnetic cell separation to suggest that chronic inflammation induced by CCL2 significantly enhances tumor growth and promotes the formation of a desmoplastic stroma through early recruitment of macrophages and fibrocytes into the tumor microenvironment.
Tue Jul 28 00:00:00 EDT 2020
Antimesothelioma Immunotherapy by CTLA-4 Blockade Depends on Active PD1-Based TWIST1 Vaccination.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Wong YC,Huang H,Man K,Chen Z
14-0112-82 was used in Flow Cytometry to demonstrate that TWIST1, the basic helix-loop-helix transcription factor, was associated with human mesothelioma tumorigenesis and is required for the invasion and metastasis of mesothelioma in the immune-competent murine AB1 model.
Fri Mar 27 00:00:00 EDT 2020
The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.
Scientific reports
Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Sep 16 00:00:00 EDT 2020
Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.
ImmunoHorizons
Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Oct 19 00:00:00 EDT 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Apr 28 00:00:00 EDT 2021
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
14-0112-82 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.
Wed Jan 01 00:00:00 EST 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.
Biomedicines
Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Dec 09 00:00:00 EST 2020
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma.
Journal for immunotherapy of cancer
Shigeta K,Matsui A,Kikuchi H,Klein S,Mamessier E,Chen IX,Aoki S,Kitahara S,Inoue K,Shigeta A,Hato T,Ramjiawan RR,Staiculescu D,Zopf D,Fiebig L,Hobbs GS,Quaas A,Dima S,Popescu I,Huang P,Munn LL,Cobbold M,Goyal L,Zhu AX,Jain RK,Duda DG
14-0112-82 was used in Flow Cytometry to conclude that judicious regorafenib/anti-PD1 combination therapy can inhibit tumor growth and increase survival by normalizing tumor vasculature and increasing intratumoral CXCR3+CD8 T-cell infiltration through elevated CXCL10 expression in HCC cells.
Sun Nov 01 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2021
L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.
Cells
Drescher HK,Schippers A,Rosenhain S,Gremse F,Bongiovanni L,Bruin A,Eswaran S,Gallage SU,Pfister D,Szydlowska M,Heikenwalder M,Weiskirchen S,Wagner N,Trautwein C,Weiskirchen R,Kroy DC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Apr 29 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Frontiers in immunology
Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Apr 12 00:00:00 EDT 2021
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Androgen Receptor Signaling Positively Regulates Monocytic Development.
Frontiers in immunology
Consiglio CR,Gollnick SO
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of androgen signaling in monocytic differentiation with a genetic mouse model of myeloid androgen receptor (AR) knockout (MARKO) and pharmacological inhibition of AR.
Thu Apr 29 00:00:00 EDT 2021
Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.
JCI insight
Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2020
Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b+Ly6G- myeloid cells.
Aging
Fang Y,Gu Y,Li L,Zhu L,Qian J,Zhao C,Xu L,Wei W,Du Y,Yuan N,Zhang S,Yuan Y,Xu Y,Jiang C,Wang J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Nov 24 00:00:00 EST 2020
Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.
Cells
Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jul 07 00:00:00 EDT 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
14-0112-82 was used in Flow Cytometry to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 EST 2019
A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves.
Immunity
Kolter J,Feuerstein R,Zeis P,Hagemeyer N,Paterson N,d'Errico P,Baasch S,Amann L,Masuda T,Lösslein A,Gharun K,Meyer-Luehmann M,Waskow C,Franzke CW,Grün D,Lämmermann T,Prinz M,Henneke P
14-0112 was used in Flow cytometry/Cell sorting to delineate the postnatal development of dermal macrophages and their differentiation into subsets by adapting single-cell transcriptomics, fate mapping, and imaging.
Tue Jun 18 00:00:00 EDT 2019
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.
Cell metabolism
Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD
14-0112 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.
Tue Dec 03 00:00:00 EST 2019
Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.
Nature immunology
Piliponsky AM,Shubin NJ,Lahiri AK,Truong P,Clauson M,Niino K,Tsuha AL,Nedospasov SA,Karasuyama H,Reber LL,Tsai M,Mukai K,Galli SJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2019
Central nervous system regeneration is driven by microglia necroptosis and repopulation.
Nature neuroscience
Lloyd AF,Davies CL,Holloway RK,Labrak Y,Ireland G,Carradori D,Dillenburg A,Borger E,Soong D,Richardson JC,Kuhlmann T,Williams A,Pollard JW,des Rieux A,Priller J,Miron VE
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.
Nature cell biology
Zhu L,Li Y,Xie X,Zhou X,Gu M,Jie Z,Ko CJ,Gao T,Hernandez BE,Cheng X,Sun SC
14-0112 was used in Flow cytometry/Cell sorting to suggest a PKCθ-TBKBP1-TBK1 growth factor signalling axis that mediates both tumour growth and immunosuppression.
Sun Dec 01 00:00:00 EST 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
14-0112-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors.
The Journal of experimental medicine
Železnjak J,Lisnić VJ,Popović B,Lisnić B,Babić M,Halenius A,L'Hernault A,Roviš TL,Hengel H,Erhard F,Redwood AJ,Vidal SM,Dölken L,Krmpotić A,Jonjić S
14-0112 was used in Flow cytometry/Cell sorting to solve a long-standing conundrum of how MCMV avoids recognition by NK cells, unravels a fundamental new viral immune evasion mechanism, and demonstrates how this forced the evolution of virus-specific activating MHC I-restricted Ly49 receptors.
Mon Aug 05 00:00:00 EDT 2019
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.
The Journal of experimental medicine
Melo-Gonzalez F,Kammoun H,Evren E,Dutton EE,Papadopoulou M,Bradford BM,Tanes C,Fardus-Reid F,Swann JR,Bittinger K,Mabbott NA,Vallance BA,Willinger T,Withers DR,Hepworth MR
14-0112-82 was used in Flow Cytometry to study the mechanisms that modulate the magnitude and quality of T cell-dependent IgA responses.
Mon Apr 01 00:00:00 EDT 2019
IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity.
The Journal of allergy and clinical immunology
Ravanetti L,Dijkhuis A,Dekker T,Sabogal Pineros YS,Ravi A,Dierdorp BS,Erjefält JS,Mori M,Pavlidis S,Adcock IM,Rao NL,Lutter R
14-0112-82 was used in Flow Cytometry to show that IL-33 drives this increased airway hyperresponsiveness and viral replication and that both lymphoid and myeloid populations infiltrate into the airway lumen and parenchyma, whereas thymic stromal lymphopoietin was redundant in this model.
Mon Apr 01 00:00:00 EDT 2019
TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.
Proceedings of the National Academy of Sciences of the United States of America
Sharma N,Vacher J,Allison JP
14-0112-82 was used in Flow Cytometry to show that this mechanism could be harnessed to modulate the clinical outcome of anti-CTLA-4 antibodies and possibly other antibody-based immunotherapies.
Tue May 21 00:00:00 EDT 2019
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation.
Immunity & ageing : I & A
Zhang L,Xu J,Gao J,Chen P,Yin M,Zhao W
14-0112-82 was used in Flow Cytometry to determine the alterations of IgG, CD19, and Aβ in various brain regions of uninfected male and female APOE3- and APOE4-TR mice at the age of 3 and 10 months to elucidate impacts of AD risk factors on alterations of brain IgG.
Thu Mar 31 00:00:00 EDT 2022
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.
PLoS biology
Łyszkiewicz M,Winter SJ,Witzlau K,Föhse L,Brownlie R,Puchałka J,Verheyden NA,Kunze-Schumacher H,Imelmann E,Blume J,Raha S,Sekiya T,Yoshimura A,Frueh JT,Ullrich E,Huehn J,Weiss S,Gutierrez MG,Prinz I,Zamoyska R,Ziętara N,Krueger A
14-0112-82 was used in Flow Cytometry to propose that intrathymic miR-181a/b-1 controls development of Treg cells and imposes a developmental legacy on their peripheral function.
Fri Mar 01 00:00:00 EST 2019
Inhibition of T cell activation and function by the adaptor protein CIN85.
Science signaling
Kong MS,Hashimoto-Tane A,Kawashima Y,Sakuma M,Yokosuka T,Kometani K,Onishi R,Carpino N,Ohara O,Kurosaki T,Phua KK,Saito T
14-0112-82 was used in Flow Cytometry to show that CIN85 (Cbl-interacting protein of 85 kDa) limited T cell responses to T cell receptor stimulation.
Tue Feb 05 00:00:00 EST 2019
Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.
British journal of pharmacology
Feng L,Sun Y,Song P,Xu L,Wu X,Wu X,Shen Y,Sun Y,Kong L,Wu X,Xu Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment.
Oncogene
De Marchi E,Orioli E,Pegoraro A,Sangaletti S,Portararo P,Curti A,Colombo MP,Di Virgilio F,Adinolfi E
14-0112-82 was used in Flow Cytometry to explore how ATP's interaction with its receptor P2X7 influences a tumour microenvironment survival mechanisms.
Wed May 01 00:00:00 EDT 2019
Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.
Journal of cellular physiology
Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Pericyte transplantation improves skeletal muscle recovery following hindlimb immobilization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Munroe M,Dvoretskiy S,Lopez A,Leong J,Dyle MC,Kong H,Adams CM,Boppart MD
14-0112-86 was used in Immunohistochemistry (Frozen) to provide the first evidence that pericytes effectively rehabilitate skeletal muscle mass following disuse atrophy.
Sat Jun 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.
Cell reports
Zeng J,Wang Y,Luo Z,Chang LC,Yoo JS,Yan H,Choi Y,Xie X,Deverman BE,Gradinaru V,Gupton SL,Zlokovic BV,Zhao Z,Jung JU
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Apr 09 00:00:00 EDT 2019
Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.
Nature communications
Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Sep 13 00:00:00 EDT 2019
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Cell reports
Matsumura T,Ikebe T,Arikawa K,Hosokawa M,Aiko M,Iguchi A,Togashi I,Kai S,Ohara S,Ohara N,Ohnishi M,Watanabe H,Kobayashi K,Takeyama H,Yamasaki S,Takahashi Y,Ato M
14-0112-82 was used in Flow Cytometry to show IFN-γ-producing immature myeloid cells can provide protection to mice in invasive group A Streptococcus infection.
Tue Apr 09 00:00:00 EDT 2019
Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses.
eLife
Carpentier KS,Davenport BJ,Haist KC,McCarthy MK,May NA,Robison A,Ruckert C,Ebel GD,Morrison TE
14-0112-82 was used in Flow Cytometry to reveal a previously unrecognized innate immune pathway that controls alphavirus viremia and dissemination in vertebrate hosts, ultimately influencing disease severity and likely transmission efficiency.
Wed Oct 09 00:00:00 EDT 2019
Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.
Scientific reports
Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Apr 10 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.
Frontiers in immunology
Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases.
Theranostics
Weiss-Sadan T,Ben-Nun Y,Maimoun D,Merquiol E,Abd-Elrahman I,Gotsman I,Blum G
14-0112-82 was used in Immunohistochemistry to demonstrate the potential utility of molecular phototherapy to ameliorate atherosclerosis burden.
Mon Aug 24 00:00:00 EDT 2020
A phospholipase D2 inhibitor, CAY10594, ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
Scientific reports
Lee SK,Bae GH,Kim YS,Kim HS,Lee M,Ghim J,Zabel BA,Ryu SH,Bae YS
14-0112-82 was used in Flow Cytometry to investigate acetaminophen-induced acute liver injury treatment.
Fri May 10 00:00:00 EDT 2019
Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.
Nature metabolism
Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Nature communications
Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Feb 22 00:00:00 EST 2019
Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D.
Nature communications
Jiang S,Lyu C,Zhao P,Li W,Kong W,Huang C,Genin GM,Du Y
14-0112-82 was used in Immunocytochemistry to discover the regulatory effect of cryoprotectants on ice crystal growth and use this property to realise separate control of the scaffold pore size and stiffness.
Fri Aug 02 00:00:00 EDT 2019
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells.
Journal for immunotherapy of cancer
Gao W,Zhang X,Yang W,Dou D,Zhang H,Tang Y,Zhong W,Meng J,Bai Y,Liu Y,Yang L,Chen S,Liu H,Yang C,Sun T
14-0112-82 was used in Flow Cytometry to investigate if a potential option for enhancing the efficacy of PD-1 inhibitors in clinical applications exists.
Wed Aug 28 00:00:00 EDT 2019
Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.
Nature communications
Duan X,Chan C,Han W,Guo N,Weichselbaum RR,Lin W
14-0112 was used in Flow cytometry/Cell sorting to conclude that the intrinsically biodegradable, well tolerated, and systemically available immunostimulatory NCP promises to enter clinical testing as an immunotherapy against colorectal cancer.
Tue Apr 23 00:00:00 EDT 2019
Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.
Frontiers in immunology
Schreiber M,Weigelt M,Karasinsky A,Anastassiadis K,Schallenberg S,Petzold C,Bonifacio E,Kretschmer K,Hommel A
14-0112 was used in Flow cytometry/Cell sorting to show that transient hyperexpression of IL-7 can impair immune regulation, through disturbances in lymphocyte development pathways, and decrease graft survival time, even under immunosuppression.
Mon Sep 14 00:00:00 EDT 2020
Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.
Oncoimmunology
Salerno F,Guislain A,Freen-Van Heeren JJ,Nicolet BP,Young HA,Wolkers MC
14-0112 was used in Flow cytometry/Cell sorting to conclude that post-transcriptional mechanisms could be modulated to potentiate effective T cell therapies in cancer.
Tue Jan 12 00:00:00 EST 2021
Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.
Nature communications
Zhu H,Bhatt B,Sivaprakasam S,Cai Y,Liu S,Kodeboyina SK,Patel N,Savage NM,Sharma A,Kaufman RJ,Li H,Singh N
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Mar 06 00:00:00 EST 2019
The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.
Scientific reports
Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jan 30 00:00:00 EST 2019
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.
Nature communications
Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Feb 12 00:00:00 EST 2019
Isolation and Culture of Microglia.
Current protocols in immunology
Bohlen CJ,Bennett FC,Bennett ML
14-0112 was used in Flow cytometry/Cell sorting to describe approaches for purification of microglia by fluorescence-activated cell sorting using microglia-specific surface markers and for enrichment of microglia by magnetic sorting and immunopanning.
Sat Jun 01 00:00:00 EDT 2019
Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.
PloS one
Mathä L,Shim H,Steer CA,Yin YH,Martinez-Gonzalez I,Takei F
14-0112-82 was used in Flow Cytometry to suggest that female ILC2s are more readily activated than male ILC2s due to their gene expression at the naïve state, which is potentially influenced by the lung environment.
Mon Dec 16 00:00:00 EST 2019
Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.
Cellular and molecular gastroenterology and hepatology
Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Apr 29 00:00:00 EDT 2019
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cell reports
Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunoprecipitation
Tue Jun 04 00:00:00 EDT 2019
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
TLR2 Promotes Monocyte/Macrophage Recruitment Into the Liver and Microabscess Formation to Limit the Spread of Listeria Monocytogenes.
Frontiers in immunology
Wang G,Zhao H,Zheng B,Li D,Yuan Y,Han Q,Tian Z,Zhang J
14-0112-82 was used in Flow Cytometry to provide insight into the intrinsic mechanisms of TLR2-induced Mo/MΦ migration and mobility, as well as the interaction between macrophages and hepatocytes in resistance to Lm infection.
Thu Oct 15 00:00:00 EDT 2020
Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.
Nature
Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Sun Apr 01 00:00:00 EDT 2018
Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.
Nature
Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 01 00:00:00 EDT 2018
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Nature
Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.
Cell research
Du X,Tang F,Liu M,Su J,Zhang Y,Wu W,Devenport M,Lazarski CA,Zhang P,Wang X,Ye P,Wang C,Hwang E,Zhu T,Xu T,Zheng P,Liu Y
14-0112 was used in in vitro experiments to show that at high concentrations, the anti-CTLA-4 antibody Ipilimumab blocks neither B7 trans-endocytosis by CTLA-4 nor CTLA-4 binding to immobilized or cell-associated B7.
Sun Apr 01 00:00:00 EDT 2018
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Immunity
Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Immunity
Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis.
Cellular & molecular immunology
Lu Y,Liu H,Bi Y,Yang H,Li Y,Wang J,Zhang Z,Wang Y,Li C,Jia A,Han L,Hu Y,Zhao Y,Wang R,Liu G
14-0112 was used in Flow cytometry/Cell sorting to reveal the dysregulation of glucocorticoid receptor expression in myeloid-derived suppressor cells during innate immunological hepatic injury and found that GR regulates the function of MDSCs through modulating HIF1α-dependent glycolysis.
Fri Jun 01 00:00:00 EDT 2018
Insulin resistance causes inflammation in adipose tissue.
The Journal of clinical investigation
Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Apr 02 00:00:00 EDT 2018
Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.
The Journal of clinical investigation
Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.
The Journal of experimental medicine
Malireddi RKS,Gurung P,Mavuluri J,Dasari TK,Klco JM,Chi H,Kanneganti TD
14-0112 was used in Flow cytometry/Cell sorting to identify a critical role for TAK1 in maintaining NLRP3 inflammasome quiescence and preserving cellular homeostasis and survival.
Mon Apr 02 00:00:00 EDT 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-0112 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 EST 2018
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
The Journal of experimental medicine
Delpoux A,Michelini RH,Verma S,Lai CY,Omilusik KD,Utzschneider DT,Redwood AJ,Goldrath AW,Benedict CA,Hedrick SM
14-0112 was used in Flow cytometry/Cell sorting to show that FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells.
Mon Feb 05 00:00:00 EST 2018
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.
Journal of the American Society of Nephrology : JASN
Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease.
The EMBO journal
Ziegler-Waldkirch S,d'Errico P,Sauer JF,Erny D,Savanthrapadian S,Loreth D,Katzmarski N,Blank T,Bartos M,Prinz M,Meyer-Luehmann M
14-0112 was used in Flow cytometry/Cell sorting to study the impact and functional consequences of induced AB deposits on neurons in Alzheimer's disease.
Wed Jan 17 00:00:00 EST 2018
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue May 01 00:00:00 EDT 2018
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue May 01 00:00:00 EDT 2018
The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease.
Aging and disease
Zhao YF,Zhang JF,Lou ZY,Zu HB,Wang ZG,Zeng WC,Xiao BG
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Mon Oct 01 00:00:00 EDT 2018
Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.
PLoS biology
Mensurado S,Rei M,Lança T,Ioannou M,Gonçalves-Sousa N,Kubo H,Malissen M,Papayannopoulos V,Serre K,Silva-Santos B
14-0112 was used in Flow cytometry/Cell sorting to study the role of tumour-associated neutrophils in the regulation of γδ17 T-cell responses in the tumour microenvironment.
Tue May 01 00:00:00 EDT 2018
Experimental Stroke Differentially Affects Discrete Subpopulations of Splenic Macrophages.
Frontiers in immunology
McCulloch L,Alfieri A,McColl BW
14-0112 was used in Flow cytometry/Cell sorting to study the effects of experimental stroke on discrete splenic macrophage subpopulations.
Tue Jul 30 00:00:00 EDT 2019
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Glia
Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection.
PLoS pathogens
Sparber F,Dolowschiak T,Mertens S,Lauener L,Clausen BE,Joller N,Stoitzner P,Tussiwand R,LeibundGut-Landmann S
14-0112 was used in Flow cytometry/Cell sorting to study innate IL-17 dependent antifungal immunity in the oral mucosa.
Tue May 01 00:00:00 EDT 2018
Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.
Journal of cellular physiology
Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.
Journal of leukocyte biology
Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.
Journal of immunology (Baltimore, Md. : 1950)
De Leon-Rodriguez CM,Rossi DCP,Fu MS,Dragotakes Q,Coelho C,Guerrero Ros I,Caballero B,Nolan SJ,Casadevall A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Jul 15 00:00:00 EDT 2018
Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain.
Journal of immunology (Baltimore, Md. : 1950)
Califano D,Furuya Y,Metzger DW
14-0112 was used in Flow cytometry/Cell sorting to resolve the apparent inconsistencies in the literature, identify mouse strain-dependent differences in the AM response to influenza infection, and ultimately may facilitate translation of the mouse model to clinical application.
Sun Jul 01 00:00:00 EDT 2018
Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development.
Journal of immunology (Baltimore, Md. : 1950)
Kostrzewski T,Borg AJ,Meng Y,Filipovic I,Male V,Wack A,DiMaggio PA,Brady HJM
14-0112 was used in Flow cytometry/Cell sorting to reveal mechanisms in NK cell development and that E4bp4 is a central hub to process extrinsic stimuli.
Thu Feb 15 00:00:00 EST 2018
Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages.
Journal of immunology (Baltimore, Md. : 1950)
Nyhoff LE,Clark ES,Barron BL,Bonami RH,Khan WN,Kendall PL
14-0112 was used in Flow cytometry/Cell sorting to raise the possibility that Btk may also be expendable for survival of mature human B cells, therefore requiring prolonged dosing to be effective, and that success of BTK inhibitors may depend in part on off-target effects.
Sun Apr 01 00:00:00 EDT 2018
MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways.
Molecular and cellular biology
Baba O,Horie T,Nakao T,Hakuno D,Nakashima Y,Nishi H,Kuwabara Y,Nishiga M,Nishino T,Ide Y,Nakazeki F,Koyama S,Kimura M,Hanada R,Kawahara M,Kimura T,Ono K
14-0112 was used in Flow cytometry/Cell sorting to indicate that miR-33 deficiency affects distribution of inflammatory monocytes through dual pathways.
Sun Jul 15 00:00:00 EDT 2018
Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.
American journal of physiology. Gastrointestinal and liver physiology
Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.
Molecular medicine reports
Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
A novel method to isolate mesenchymal stem cells from mouse umbilical cord.
Molecular medicine reports
Zhang B,Zhang J,Shi H,Mao F,Wang J,Yan Y,Zhang X,Qian H,Xu W
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Morphine-potentiated cognitive deficits correlate to suppressed hippocampal iNOS RNA expression and an absent type 1 interferon response in LP-BM5 murine AIDS.
Journal of neuroimmunology
McLane VD,Kumar S,Leeming R,Rau S,Willis CL,Cao L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Jun 15 00:00:00 EDT 2018
Morphine-potentiated cognitive deficits correlate to suppressed hippocampal iNOS RNA expression and an absent type 1 interferon response in LP-BM5 murine AIDS.
Journal of neuroimmunology
McLane VD,Kumar S,Leeming R,Rau S,Willis CL,Cao L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Jun 15 00:00:00 EDT 2018
Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.
Experimental and therapeutic medicine
Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain.
eNeuro
Wakley AA,Leeming R,Malon J,Arabatzis TJ,Yuen Koh W,Cao L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Fri Apr 19 00:00:00 EDT 2019
Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.
JCI insight
Flemming S,Luissint AC,Nusrat A,Parkos CA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Oct 18 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Sep 30 00:00:00 EDT 2020
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Sep 30 00:00:00 EDT 2020
Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.
Journal of neuroinflammation
Wilson KD,Ochoa LF,Solomon OD,Pal R,Cardona SM,Carpio VH,Keiser PH,Cardona AE,Vargas G,Stephens R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Mon Jun 04 00:00:00 EDT 2018
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Nature communications
Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Neutralization
Fri Mar 02 00:00:00 EST 2018
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
JCI insight
Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Feb 08 00:00:00 EST 2018
Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points.
Epigenetics & chromatin
Heuston EF,Keller CA,Lichtenberg J,Giardine B,Anderson SM,Hardison RC,Bodine DM
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that megakaryopoietic profiles are established early in haematopoiesis and are present in the majority of the haematopoietic progenitor population.
Mon May 28 00:00:00 EDT 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Apr 18 00:00:00 EDT 2018
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Sep 25 00:00:00 EDT 2019
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Genome biology
Grigoryan A,Guidi N,Senger K,Liehr T,Soller K,Marka G,Vollmer A,Markaki Y,Leonhardt H,Buske C,Lipka DB,Plass C,Zheng Y,Mulaw MA,Geiger H,Florian MC
14-0112 was used in Flow cytometry/Cell sorting to show that not all histone modifications display a polar localization and that a reduction in H4K16ac amount and loss of epipolarity are specific to aged HSCs.
Wed Nov 07 00:00:00 EST 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.
Nature communications
Asada S,Goyama S,Inoue D,Shikata S,Takeda R,Fukushima T,Yonezawa T,Fujino T,Hayashi Y,Kawabata KC,Fukuyama T,Tanaka Y,Yokoyama A,Yamazaki S,Kozuka-Hata H,Oyama M,Kojima S,Kawazu M,Mano H,Kitamura T
14-0112 was used in Flow cytometry/Cell sorting to examine the mechanism by which mutant ASXenopus laevis1 promotes myeloid leukaemogenesis.
Mon Jul 16 00:00:00 EDT 2018
TCRαβ/CD3 disruption enables CD3-specific antileukemic T cell immunotherapy.
JCI insight
Rasaiyaah J,Georgiadis C,Preece R,Mock U,Qasim W
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that 3CAR T cells mediated potent antileukemic effects in a human/murine chimeric model, supporting the application of cellular immunotherapy strategies against T cell malignancies.
Thu Jul 12 00:00:00 EDT 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.
Oncotarget
Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Apr 03 00:00:00 EDT 2018
An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.
Scientific reports
Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 02 00:00:00 EDT 2018
Early cellular interactions and immune transcriptome profiles in human factor VIII-exposed hemophilia A mice.
Journal of thrombosis and haemostasis : JTH
Lai JD,Cartier D,Hartholt RB,Swystun LL,van Velzen AS,den Haan JMM,Hough C,Voorberg J,Lillicrap D
14-0112 was used in Immunohistochemistry to assess cellular interactions and expression profiles in hemophilia A mice.
Thu Mar 01 00:00:00 EST 2018
Mast Cells Respond to Candida albicans Infections and Modulate Macrophages Phagocytosis of the Fungus.
Frontiers in immunology
De Zuani M,Paolicelli G,Zelante T,Renga G,Romani L,Arzese A,Pucillo CEM,Frossi B
14-0112 was used in Immunocytochemistry-immunoflourescence to unravel the mechanisms of reciprocal influence between mucosal mast cells (MCs) and Candida albicans as commensal/opportunistic pathogen species in humans.
Thu Oct 03 00:00:00 EDT 2019
TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival.
Nature communications
Zhu L,Xie X,Zhang L,Wang H,Jie Z,Zhou X,Shi J,Zhao S,Zhang B,Cheng X,Sun SC
14-0112 was used in Flow cytometry/Cell sorting to study the mechanism of IL-15 function in autophagy and natural killer cell survival.
Wed Jul 18 00:00:00 EDT 2018
Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury.
Respiratory research
Ni K,Gill A,Tseng V,Mikosz AM,Koike K,Beatman EL,Xu CY,Cao D,Gally F,Mould KJ,Serban KA,Schweitzer KS,March KL,Janssen WJ,Nozik-Grayck E,Garantziotis S,Petrache I
14-0112 was used in Flow cytometry/Cell sorting to show the covalent HC-HA binding, which is exclusively mediated by tumor necrosis factor α (TNFα)-stimulated-gene-6 (TSG-6), may play an important role in the onset or the resolution of lung inflammation in acute lung injury (ALI) induced by respiratory infection.
Thu May 31 00:00:00 EDT 2018
Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis.
Nature communications
Mencarelli A,Khameneh HJ,Fric J,Vacca M,El Daker S,Janela B,Tang JP,Nabti S,Balachander A,Lim TS,Ginhoux F,Ricciardi-Castagnoli P,Mortellaro A
14-0112 was used in Flow cytometry/Cell sorting to show that mice lacking Calcineurin B in CD11chighMHCII+ cells spontaneously develop intestinal inflammation and are susceptible to induced colitis.
Fri Mar 16 00:00:00 EDT 2018
Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA.
Scientific reports
Dyer MR,Chen Q,Haldeman S,Yazdani H,Hoffman R,Loughran P,Tsung A,Zuckerbraun BS,Simmons RL,Neal MD
14-0112 was used in Flow cytometry/Cell sorting to study the underlying pathophysiology of venous thromboembolic disease.
Thu Feb 01 00:00:00 EST 2018
A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.
Nature communications
Guarnerio J,Mendez LM,Asada N,Menon AV,Fung J,Berry K,Frenette PS,Ito K,Pandolfi PP
14-0112 was used in Flow cytometry/Cell sorting to show Pml in mesenchymal stem cells regulate pro-inflammatory cytokines which may sustain leukemic cells.
Thu Jan 04 00:00:00 EST 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.
Nature medicine
Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Nature
Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 18 00:00:00 EDT 2017
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Nature
Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 18 00:00:00 EDT 2017
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Apr 06 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.
The Journal of clinical investigation
Kim W,Khan SK,Gvozdenovic-Jeremic J,Kim Y,Dahlman J,Kim H,Park O,Ishitani T,Jho EH,Gao B,Yang Y
14011282 was used in flow cytometry to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma
Tue Jan 03 00:00:00 EST 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.
The Journal of clinical investigation
Taylor RA,Chang CF,Goods BA,Hammond MD,Mac Grory B,Ai Y,Steinschneider AF,Renfroe SC,Askenase MH,McCullough LD,Kasner SE,Mullen MT,Hafler DA,Love JC,Sansing LH
14-0112 was used in Flow cytometry/Cell sorting to investigate the specific responses of microglia following intracerebral haemorrhage with the aim of identifying pathways that may aid in recovery after brain injury.
Tue Jan 03 00:00:00 EST 2017
LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Xu X,Han L,Zhao G,Xue S,Gao Y,Xiao J,Zhang S,Chen P,Wu ZY,Ding J,Hu R,Wei B,Wang H
14-0112 was used in Flow cytometry/Cell sorting to demonstrate LRCH1 as a novel effector to restrain PKCα-DOCK8-Cdc42 module-induced T cell migration and ameliorate EAE.
Sun Jan 01 00:00:00 EST 2017
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.
The Journal of experimental medicine
Singh PB,Pua HH,Happ HC,Schneider C,von Moltke J,Locksley RM,Baumjohann D,Ansel KM
14-0112 was used in Flow cytometry/Cell sorting to establish the physiological requirements for miRNAs in ILC2 homeostasis and immune function ans compare the global miRNA repertoire of resting and activated ILC2s and T helper type 2 cells.
Mon Dec 04 00:00:00 EST 2017
Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.
The EMBO journal
Kawasaki T,Ito K,Miyata H,Akira S,Kawai T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jun 14 00:00:00 EDT 2017
Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.
Autophagy
Qiang L,Sample A,Shea CR,Soltani K,Macleod KF,He YY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Jul 05 00:00:00 EDT 2019
Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma.
Neuro-oncology
Antonios JP,Soto H,Everson RG,Moughon D,Orpilla JR,Shin NP,Sedighim S,Treger J,Odesa S,Tucker A,Yong WH,Li G,Cloughesy TF,Liau LM,Prins RM
14-0112 was used in Immunohistochemistry to elucidate the role that TIMs play in mediating adaptive immune resistance in the GBM microenvironment and provide evidence that they can be manipulated pharmacologically with agents that are clinically available.
Thu Jun 01 00:00:00 EDT 2017
C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America
Troegeler A,Mercier I,Cougoule C,Pietretti D,Colom A,Duval C,Vu Manh TP,Capilla F,Poincloux R,Pingris K,Nigou J,Rademann J,Dalod M,Verreck FA,Al Saati T,Lugo-Villarino G,Lepenies B,Hudrisier D,Neyrolles O
14-0112 was used in Flow cytometry/Cell sorting to reveal the modulatory role of the C-type lectin, DCIR, in tuberculosis-associated inflammation.
Tue Jan 24 00:00:00 EST 2017
Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms.
Proceedings of the National Academy of Sciences of the United States of America
Briseño CG,Gargaro M,Durai V,Davidson JT,Theisen DJ,Anderson DA,Novack DV,Murphy TL,Murphy KM
14-0112 was used in Flow cytometry/Cell sorting to suggest that there is an unrecognized but critical role for RelB within the nonhematopoietic niche that controls normal myelopoiesis.
Tue Apr 11 00:00:00 EDT 2017
Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Proceedings of the National Academy of Sciences of the United States of America
Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
Primary Tumors Limit Metastasis Formation through Induction of IL15-Mediated Cross-Talk between Patrolling Monocytes and NK Cells.
Cancer immunology research
Kubo H,Mensurado S,Gonçalves-Sousa N,Serre K,Silva-Santos B
14-0112 was used in Flow cytometry/Cell sorting to identifies an innate cell network and the molecular determinants responsible for metastasis immunosurveillance, providing support for using the key molecular mediator to improve immunotherapeutic outcomes.
Fri Sep 01 00:00:00 EDT 2017
Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa.
Frontiers in immunology
Blank T,Goldmann T,Koch M,Amann L,Schön C,Bonin M,Pang S,Prinz M,Burnet M,Wagner JE,Biel M,Michalakis S
14-0112 was used in Flow cytometry/Cell sorting to study microglia activation in the development of retinitis pigmentosa.
Wed Nov 20 00:00:00 EST 2019
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.
The Journal of cell biology
Vander Lugt B,Riddell J,Khan AA,Hackney JA,Lesch J,DeVoss J,Weirauch MT,Singh H,Mellman I
14-0112 was used in Flow cytometry/Cell sorting to study how DCs modulate their ability to prime tolerogenic or immunogenic T cells by expressing a core antigen presentation module that is overlaid by distinctive regulatory modules to promote either tolerance or immunity.
Mon Mar 06 00:00:00 EST 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-0112-82 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 EDT 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation.
European journal of immunology
Miletic A,Lenartic M,Popovic B,Brizic I,Trsan T,Miklic K,Mandelboim O,Krmpotic A,Jonjic S
14-0112 was used in Flow cytometry/Cell sorting to provide evidence for the role of NCR1 in antibody response to mouse cytomegalovirus infection.
Fri Sep 01 00:00:00 EDT 2017
Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang W,Wang H,Zhou X,Li X,Sun W,Dellinger M,Boyce BF,Xing L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin β1 Recycling.
Journal of immunology (Baltimore, Md. : 1950)
Lee H,Zhang D,Wu J,Otterbein LE,Jin Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.
Journal of cellular biochemistry
Vafaei R,Nassiri SM,Siavashi V
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment.
Acta ophthalmologica
Bignami F,Lorusso A,Rama P,Ferrari G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2.
Alcoholism, clinical and experimental research
Lawrimore CJ,Crews FT
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.
Oncotarget
Li CG,Yan L,Jing YY,Xu LH,Liang YD,Wei HX,Hu B,Pan H,Zha QB,Ouyang DY,He XH
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Tue Jan 03 00:00:00 EST 2017
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Scientific reports
Kuboyama T,Wahane S,Huang Y,Zhou X,Wong JK,Koemeter-Cox A,Martini M,Friedel RH,Zou H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Thu Aug 17 00:00:00 EDT 2017
Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice.
Journal of neuroinflammation
Knoll JG,Krasnow SM,Marks DL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Nov 09 00:00:00 EST 2017
Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice.
Journal of neuroinflammation
Knoll JG,Krasnow SM,Marks DL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Nov 09 00:00:00 EST 2017
Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.
Oncotarget
Zamanian-Daryoush M,Lindner DJ,DiDonato JA,Wagner M,Buffa J,Rayman P,Parks JS,Westerterp M,Tall AR,Hazen SL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Sep 22 00:00:00 EDT 2017
Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.
Scientific reports
Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 05 00:00:00 EDT 2017
Alternative activation generates IL-10 producing type 2 innate lymphoid cells.
Nature communications
Seehus CR,Kadavallore A,Torre B,Yeckes AR,Wang Y,Tang J,Kaye J
14-0112 was used in Immunocytochemistry to demonstrate the generation of a previously unappreciated IL-10 producing type 2 innate lymphoid cell effector cell population.
Fri Dec 01 00:00:00 EST 2017
Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis.
Stem cell research & therapy
Xue XL,Han XD,Li Y,Chu XF,Miao WM,Zhang JL,Fan SJ
14-0112 was used in Flow cytometry/Cell sorting to suggest that ATX could be used as a potent therapeutic agent to protect the hematopoietic system against TBI-induced bone marrow suppression.
Mon Jan 23 00:00:00 EST 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury.
Cell death & disease
Zhang C,Wang S,Li J,Zhang W,Zheng L,Yang C,Zhu T,Rong R
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of myeloid-derived suppressor cells and mTOR signalling in the protection of acute kidney injury.
Thu Mar 23 00:00:00 EDT 2017
Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.
Stem cell research & therapy
Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Nov 10 00:00:00 EST 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.
Nature communications
Rayes J,Lax S,Wichaiyo S,Watson SK,Di Y,Lombard S,Grygielska B,Smith SW,Skordilis K,Watson SP
14-0112 was used in Flow cytometry/Cell sorting to demonstrate, through two mouse models of sepsis, the anti-inflammatory role of the podoplanin-CLEC-2 axis.
Thu Dec 21 00:00:00 EST 2017
Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.
Cell death & disease
Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells.
Scientific reports
Nakamizo S,Honda T,Adachi A,Nagatake T,Kunisawa J,Kitoh A,Otsuka A,Dainichi T,Nomura T,Ginhoux F,Ikuta K,Egawa G,Kabashima K
14-0112 was used in Flow cytometry/Cell sorting to indicate that HFD is a key element in exacerbation of IMQ-induced psoriatic dermatitis, and further raise the possibility of HFD as a factor that links obesity and psoriasis.
Thu Oct 26 00:00:00 EDT 2017
Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.
NPJ vaccines
Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.
Particle and fibre toxicology
Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 14 00:00:00 EDT 2017
Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.
JCI insight
Kienhöfer D,Hahn J,Stoof J,Csepregi JZ,Reinwald C,Urbonaviciute V,Johnsson C,Maueröder C,Podolska MJ,Biermann MH,Leppkes M,Harrer T,Hultqvist M,Olofsson P,Munoz LE,Mocsai A,Herrmann M,Schett G,Holmdahl R,Hoffmann MH
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 18 00:00:00 EDT 2017
Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.
Nature communications
Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Oct 16 00:00:00 EDT 2017
CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells.
Oncoimmunology
Bou Nasser Eddine F,Forlani G,Lombardo L,Tedeschi A,Tosi G,Accolla RS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model.
Oncoimmunology
Gebauer C,Pignolet B,Yshii L,Mauré E,Bauer J,Liblau R
14-0112 was used in Flow cytometry/Cell sorting to provide further insight into the cellular mechanisms whereby a potent anti-tumor immunity triggers a cancer-associated autoimmune disease, and may therefore help to develop new therapeutic strategies against PND.
Tue Jan 12 00:00:00 EST 2021
WASH maintains NKp46+ ILC3 cells by promoting AHR expression.
Nature communications
Xia P,Liu J,Wang S,Ye B,Du Y,Xiong Z,Han ZG,Tong L,Fan Z
14-0112 was used in Flow cytometry/Cell sorting to study how WASH-mediated AHR expression has a critical function in the maintenance of NKp46(+) ILC3s.
Wed Jun 07 00:00:00 EDT 2017
Autophagy is a signature of a signaling network that maintains hematopoietic stem cells.
PloS one
Nguyen-McCarty M,Klein PS
14-0112 was used in Flow cytometry/Cell sorting to identify the downstream effectors of mTORC1 in hematopoietic stem cells.
Fri Sep 15 00:00:00 EDT 2017
Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis.
PloS one
Tornack J,Reece ST,Bauer WM,Vogelzang A,Bandermann S,Zedler U,Stingl G,Kaufmann SH,Melchers F
14-0112-82 was used in Flow Cytometry to conclude that LT-pHSCs, together with MSCs of Mtb-infected humans and mice serve as a hitherto unappreciated quiescent cellular depot for Mtb during latent TB infection.
Tue Sep 05 00:00:00 EDT 2017
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
JCI insight
Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells.
Nature medicine
Massoud AH,Charbonnier LM,Lopez D,Pellegrini M,Phipatanakul W,Chatila TA
14-0112 was used in Flow cytometry/Cell sorting to identify a previously unknown mechanism for the development of TH17 cell inflammation in genetically prone individuals.
Thu Sep 01 00:00:00 EDT 2016
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence.
Nature
Ibiza S,García-Cassani B,Ribeiro H,Carvalho T,Almeida L,Marques R,Misic AM,Bartow-McKenney C,Larson DM,Pavan WJ,Eberl G,Grice EA,Veiga-Fernandes H
14011282 was used in flow cytometry to explain how glial cells impact ILC3-derived IL-22
Thu Jul 21 00:00:00 EDT 2016
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nature immunology
Monticelli LA,Buck MD,Flamar AL,Saenz SA,Tait Wojno ED,Yudanin NA,Osborne LC,Hepworth MR,Tran SV,Rodewald HR,Shah H,Cross JR,Diamond JM,Cantu E,Christie JD,Pearce EL,Artis D
14-0112 was used in Flow cytometry/Cell sorting to identify Arg1 as a key regulator of group 2 innate lymphoid cell bioenergetics that control proliferative capacity and pro-inflammatory functions.
Wed Jun 01 00:00:00 EDT 2016
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Nature immunology
Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circulation research
Sager HB,Hulsmans M,Lavine KJ,Moreira MB,Heidt T,Courties G,Sun Y,Iwamoto Y,Tricot B,Khan OF,Dahlman JE,Borodovsky A,Fitzgerald K,Anderson DG,Weissleder R,Libby P,Swirski FK,Nahrendorf M
14-0112 was used in Flow cytometry/Cell sorting to elucidate the origin and roles of macrophages in the post-myocardial infarction remodelling of nonischaemic remote myocardium.
Fri Sep 16 00:00:00 EDT 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors.
The Journal of clinical investigation
Cheng Y,Chikwava K,Wu C,Zhang H,Bhagat A,Pei D,Choi JK,Tong W
14-0112 was used in Flow cytometry/Cell sorting to investigate how LNK regulates normal B cell development or promotes leukemogenesis.
Fri Apr 01 00:00:00 EDT 2016
Alternatively activated macrophages determine repair of the infarcted adult murine heart.
The Journal of clinical investigation
Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
The Journal of experimental medicine
Henry EK,Sy CB,Inclan-Rico JM,Espinosa V,Ghanny SS,Dwyer DF,Soteropoulos P,Rivera A,Siracusa MC
14011282 was used in flow cytometry to find a role for Car enzymes in regulating mast cell lineage commitment
Mon Aug 22 00:00:00 EDT 2016
Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.
Journal of autoimmunity
Yang JB,Wang YH,Yang W,Lu FT,Ma HD,Zhao ZB,Jia YJ,Tang W,Tsuneyama K,Ridgway WM,Gershwin ME,Lian ZX
14-0112 was used in Magnetic cell separation to investigate the pathways that lead to pathology in a model of primary biliary cirrhosis, showing that CD4(-/-) mice had more severe pathology and parabiosis reduced chalangitis.
Fri Jan 01 00:00:00 EST 2016
The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.
Science signaling
Billings EA,Lee CS,Owen KA,D'Souza RS,Ravichandran KS,Casanova JE
14-0112 was used in Flow cytometry/Cell sorting to demonstrate the role of GPCR BAI1 in the clearance of gram-negative bacteria by stimulation of phagocytosis and initiation of reactive oxygen species production in macrophages.
Tue Feb 02 00:00:00 EST 2016
ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.
Frontiers in immunology
Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo.
Oncogene
Hobbs RP,Batazzi AS,Han MC,Coulombe PA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Oct 27 00:00:00 EDT 2016
The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells.
Oncogene
Tang W,Wang H,Ha HL,Tassi I,Bhardwaj R,Claudio E,Siebenlist U
14-0112 was used in Flow cytometry/Cell sorting to study the role of Bcl-3 in AOM/DSS induced colon tumours.
Thu Dec 01 00:00:00 EST 2016
Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.
Mucosal immunology
Mohapatra A,Van Dyken SJ,Schneider C,Nussbaum JC,Liang HE,Locksley RM
14-0112 was used in Flow cytometry/Cell sorting to study how ILC2s link alveolar function to regulation of airway flow, revealing a key interaction between resident lymphoid and structural cells that might underlie similar organisational hierarchies in other organs.
Fri Jan 01 00:00:00 EST 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens.
PLoS pathogens
Meliopoulos VA,Van de Velde LA,Van de Velde NC,Karlsson EA,Neale G,Vogel P,Guy C,Sharma S,Duan S,Surman SL,Jones BG,Johnson MD,Bosio C,Jolly L,Jenkins RG,Hurwitz JL,Rosch JW,Sheppard D,Thomas PG,Murray PJ,Schultz-Cherry S
14-0112 was used in Flow cytometry/Cell sorting to show that upregulation of the epithelial integrin αVβ6 during influenza infection is involved in disease pathogenesis.
Mon Aug 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon.
Journal of virology
Birdwell LD,Zalinger ZB,Li Y,Wright PW,Elliott R,Rose KM,Silverman RH,Weiss SR
14-0112 was used in Flow cytometry/Cell sorting to investigate the contributions of Oas gene expression, basal IFN signalling, and virus-induced IFN to RNase L activation.
Wed Jan 06 00:00:00 EST 2016
Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.
Journal of cellular physiology
Li Y,Adomat H,Guns ET,Hojabrpour P,Duronio V,Curran TA,Jalili RB,Jia W,Delwar Z,Zhang Y,Elizei SS,Ghahary A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunocytochemistry
Wed Jun 01 00:00:00 EDT 2016
Dual-therapy with αvβ3-targeted Sn2 lipase-labile fumagillin-prodrug nanoparticles and zoledronic acid in the Vx2 rabbit tumor model.
Nanomedicine : nanotechnology, biology, and medicine
Esser AK,Schmieder AH,Ross MH,Xiang J,Su X,Cui G,Zhang H,Yang X,Allen JS,Williams T,Wickline SA,Pan D,Lanza GM,Weilbaecher KN
14-0112-82 was used in Immunohistochemistry to provide an insight to the design of future drugs against cancers.
Fri Jan 01 00:00:00 EST 2016
Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.
Journal of ginseng research
Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.
Journal of ginseng research
Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis.
Laboratory investigation; a journal of technical methods and pathology
Connor AL,Kelley PM,Tempero RM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Mar 01 00:00:00 EST 2016
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.
Journal of immunology (Baltimore, Md. : 1950)
Rota G,Ludigs K,Siegert S,Tardivel A,Morgado L,Reith W,De Gassart A,Guarda G
14-0112 was used in Flow cytometry/Cell sorting to show that Nlrc5 deficiency is not sufficient to hinder T cell activation, highlighting the robustness of the T cell priming process by activated dendritic cells.
Fri Apr 01 00:00:00 EDT 2016
Type I IFN Does Not Promote Susceptibility to Foodborne Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950)
Pitts MG,Myers-Morales T,D'Orazio SE
14-0112 was used in Flow cytometry/Cell sorting to investigate whether type I IFN promotes susceptibility to foodborne Listeria monocytogenes.
Fri Apr 01 00:00:00 EDT 2016
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Journal of immunology (Baltimore, Md. : 1950)
Harakal J,Rival C,Qiao H,Tung KS
14-0112-82 was used in Flow Cytometry to suggest that Tregs maintain physiological tolerance to clinically relevant gastric autoantigens, and Th2 responses can be a pathogenic mechanism in AIG.
Fri Jul 01 00:00:00 EDT 2016
Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning.
Journal of immunology (Baltimore, Md. : 1950)
Müller AM,Florek M,Kohrt HE,Küpper NJ,Filatenkov A,Linderman JA,Hadeiba H,Negrin RS,Shizuru JA
14-0112 was used in Flow cytometry/Cell sorting to shed new light on the effects of CD4+ T cells on HSC biology.
Tue Nov 15 00:00:00 EST 2016
Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro.
Journal of immunology research
Ufimtseva E
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Nov 08 00:00:00 EST 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Dynamics of the spleen and its significance in a murine H22 orthotopic hepatoma model.
Experimental biology and medicine (Maywood, N.J.)
Li B,Zhang S,Huang N,Chen H,Wang P,Li J,Pu Y,Yang J,Li Z
14-0112-82 was used in Flow Cytometry to study the dynamics of the spleen and its significance in a murine H22 orthotopic hepatoma model.
Fri Apr 01 00:00:00 EDT 2016
Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection.
Infection and immunity
Chen G,Wang SH,Jang JC,Odegaard JI,Nair MG
14-0112 was used in Flow cytometry/Cell sorting to delineate the function of two resistin-like molecules, RELMα and RELMβ, following infection with hookworm.
Fri Apr 01 00:00:00 EDT 2016
Rho kinase II interference by small hairpin RNA ameliorates 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine‑induced parkinsonism in mice.
Molecular medicine reports
Zhang Q,Zhao YF,Xi JY,Yu WB,Xiao BG
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Dec 01 00:00:00 EST 2016
Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.
Iranian journal of basic medical sciences
Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Macrophages form functional vascular mimicry channels in vivo.
Scientific reports
Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Fri Nov 11 00:00:00 EST 2016
Macrophages form functional vascular mimicry channels in vivo.
Scientific reports
Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Fri Nov 11 00:00:00 EST 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion.
eLife
Gao L,Gülcüler GS,Golbach L,Block H,Zarbock A,Martin-Villalba A
14-0112 was used in Flow cytometry/Cell sorting to identify the mechanisms underlying the chemoattractant effect of endothelial cell-derived CD95L in induction of neutrophil recruitment.
Thu Oct 20 00:00:00 EDT 2016
Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion.
eLife
Gao L,Gülcüler GS,Golbach L,Block H,Zarbock A,Martin-Villalba A
14-0112 was used in Flow cytometry/Cell sorting to identify the mechanisms underlying the chemoattractant effect of endothelial cell-derived CD95L in induction of neutrophil recruitment.
Thu Oct 20 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jul 28 00:00:00 EDT 2016
A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis.
PloS one
Fransén-Pettersson N,Duarte N,Nilsson J,Lundholm M,Mayans S,Larefalk Å,Hannibal TD,Hansen L,Schmidt-Christensen A,Ivars F,Cardell S,Palmqvist R,Rozell B,Holmberg D
14-0112 was used in Flow cytometry/Cell sorting to establish a new mouse model which spontaneously develops progressive inflammation and fibrosis in multiple organs.
Mon Jul 24 00:00:00 EDT 2017
Endothelial Cell-Selective Adhesion Molecule Expression in Hematopoietic Stem/Progenitor Cells Is Essential for Erythropoiesis Recovery after Bone Marrow Injury.
PloS one
Sudo T,Yokota T,Okuzaki D,Ueda T,Ichii M,Ishibashi T,Isono T,Habuchi Y,Oritani K,Kanakura Y
14-0112 was used in Flow cytometry/Cell sorting to determine the physiological importance of Endothelial Cell-Selective Adhesion Molecule (ESAM) in erythroid recovery, showing that ESAM is essential for erthryopoiesis recovery following bone marrow injury.
Tue Mar 14 00:00:00 EDT 2017
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Nature communications
Göbel K,Pankratz S,Asaridou CM,Herrmann AM,Bittner S,Merker M,Ruck T,Glumm S,Langhauser F,Kraft P,Krug TF,Breuer J,Herold M,Gross CC,Beckmann D,Korb-Pap A,Schuhmann MK,Kuerten S,Mitroulis I,Ruppert C,Nolte MW,Panousis C,Klotz L,Kehrel B,Korn T,Langer HF,Pap T,Nieswandt B,Wiendl H,Chavakis T,Kleinschnitz C,Meuth SG
14-0112 was used in Flow cytometry/Cell sorting to study how immune activation by FXII is mediated by dendritic cells in a CD87-dependent manner, and involves alterations in intracellular cyclic AMP formation.
Wed May 18 00:00:00 EDT 2016
Brain trauma elicits non-canonical macrophage activation states.
Journal of neuroinflammation
Kim CC,Nakamura MC,Hsieh CL
14-0112 was used in Flow cytometry/Cell sorting to investigate the novel activation states involved in the early macrophage response to traumatic brain injury.
Tue May 24 00:00:00 EDT 2016
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Oncoimmunology
Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor.
Scientific reports
Brandstätter O,Schanz O,Vorac J,König J,Mori T,Maruyama T,Korkowski M,Haarmann-Stemmann T,von Smolinski D,Schultze JL,Abel J,Esser C,Takeyama H,Weighardt H,Förster I
14-0112 was used in Flow cytometry/Cell sorting to highlight the physiologic importance of cell-type specific balancing of AhR/AhRR expression in response to microbial, nutritional and other environmental stimuli.
Tue May 17 00:00:00 EDT 2016
Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.
JCI insight
Wang Y,Golden JB,Fritz Y,Zhang X,Diaconu D,Camhi MI,Gao H,Dawes SM,Xing X,Ganesh SK,Gudjonsson JE,Simon DI,McCormick TS,Ward NL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Dec 08 00:00:00 EST 2016
Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.
mBio
Shepardson KM,Larson K,Morton RV,Prigge JR,Schmidt EE,Huber VC,Rynda-Apple A
14-0112 was used in Flow cytometry/Cell sorting to investigate the response to methicillin-resistant Staphylococcus aureus following infection with influenza A virus.
Tue May 03 00:00:00 EDT 2016
Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis.
Nature communications
Guglietta S,Chiavelli A,Zagato E,Krieg C,Gandini S,Ravenda PS,Bazolli B,Lu B,Penna G,Rescigno M
14-0112 was used in Flow cytometry/Cell sorting to provide a mechanistic explanation for the tumour-promoting effects of hypercoagulation.
Mon Mar 21 00:00:00 EDT 2016
Immune signatures of protective spleen memory CD8 T cells.
Scientific reports
Brinza L,Djebali S,Tomkowiak M,Mafille J,Loiseau C,Jouve PE,de Bernard S,Buffat L,Lina B,Ottmann M,Rosa-Calatrava M,Schicklin S,Bonnefoy N,Lauvau G,Grau M,Wencker M,Arpin C,Walzer T,Leverrier Y,Marvel J
14-0112 was used in Flow cytometry/Cell sorting to identify a range of qualities uniquely associated with protective memory cells.
Thu Nov 24 00:00:00 EST 2016
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
The impact of ranitidine on monocyte responses in the context of solid tumors.
Oncotarget
Vila-Leahey A,Rogers D,Marshall JS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation.
Nature communications
Cao W,Guo J,Wen X,Miao L,Lin F,Xu G,Ma R,Yin S,Hui Z,Chen T,Guo S,Chen W,Huang Y,Liu Y,Wang J,Wei L,Wang L
14-0112 was used in Flow cytometry/Cell sorting to investigate whether the CpG-binding protein Cxxc1 plays a role in thymocyte development.
Mon May 23 00:00:00 EDT 2016
Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto.
Scientific reports
Martínez Gómez JM,Periasamy P,Dutertre CA,Irving AT,Ng JH,Crameri G,Baker ML,Ginhoux F,Wang LF,Alonso S
14-0112 was used in Flow cytometry/Cell sorting to identify the unique properties of the bat immune system that enable them to act as a reservoir for viruses that are highly pathogenic to humans.
Thu Nov 24 00:00:00 EST 2016
Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.
The Journal of biological chemistry
Wang B,Merillat SA,Vincent M,Huber AK,Basrur V,Mangelberger D,Zeng L,Elenitoba-Johnson K,Miller RA,Irani DN,Dlugosz AA,Schnell S,Scaglione KM,Paulson HL
14-0112 was used in Flow cytometry/Cell sorting to establish that UBE2W is an important protein for early postnatal survival and the normal functioning of multiple organ systems.
Fri Feb 05 00:00:00 EST 2016
Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells.
PLoS genetics
Lomada D,Jain M,Bolner M,Reeh KA,Kang R,Reddy MC,DiGiovanni J,Richie ER
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that in addition to the NFkB pathway, Stat3-mediated signals play an essential role in regulating mTEC cellularity and medullary region homeostasis.
Fri Jan 01 00:00:00 EST 2016
Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice.
Scientific reports
Watari K,Shibata T,Nabeshima H,Shinoda A,Fukunaga Y,Kawahara A,Karasuyama K,Fukushi J,Iwamoto Y,Kuwano M,Ono M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2016
CXCR3 signaling in glial cells ameliorates experimental autoimmune encephalomyelitis by restraining the generation of a pro-Th17 cytokine milieu and reducing CNS-infiltrating Th17 cells.
Journal of neuroinflammation
Chung CY,Liao F
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that CXCR3 in glial cells is critical in restraining the pro-Th17 cytokine/chemokine milieu during experimental autoimmune encephalomyelitis.
Mon Apr 11 00:00:00 EDT 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
IL-6 Signaling in Myelomonocytic Cells Is Not Crucial for the Development of IMQ-Induced Psoriasis.
PloS one
Klebow S,Hahn M,Nikoalev A,Wunderlich FT,Hövelmeyer N,Karbach SH,Waisman A
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of IL-6 signalling in myelomonocytic cells during experimental psoriasis.
Sun Jul 31 00:00:00 EDT 2016
PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes.
Immunoendocrinology (Houston, Tex.)
Martinov T,Spanier JA,Pauken KE,Fife BT
14-0112 was used in Flow cytometry/Cell sorting to understand the role of PD-1 in maintaining islet-specific tolerance in diabetes-resistant strains.
Wed Mar 30 00:00:00 EDT 2022
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.
Nature
Mesa KR,Rompolas P,Zito G,Myung P,Sun TY,Brown S,Gonzalez DG,Blagoev KB,Haberman AM,Greco V
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Jun 04 00:00:00 EDT 2015
CXCR3 chemokine receptor enables local CD8(+) T cell migration for the destruction of virus-infected cells.
Immunity
Hickman HD,Reynoso GV,Ngudiankama BF,Cush SS,Gibbs J,Bennink JR,Yewdell JW
14-0112 was used in Flow cytometry/Cell sorting to investigate how CD8(+) T cells locate virus-infected cells within tissues, showing that the CXCR3 chemokine receptor enables migration for the destruction of virus-infected cells.
Tue Mar 17 00:00:00 EDT 2015
CXCR3 chemokine receptor enables local CD8(+) T cell migration for the destruction of virus-infected cells.
Immunity
Hickman HD,Reynoso GV,Ngudiankama BF,Cush SS,Gibbs J,Bennink JR,Yewdell JW
14-0112 was used in Flow cytometry/Cell sorting to investigate how CD8(+) T cells locate virus-infected cells within tissues, showing that the CXCR3 chemokine receptor enables migration for the destruction of virus-infected cells.
Tue Mar 17 00:00:00 EDT 2015
Host microbiota constantly control maturation and function of microglia in the CNS.
Nature neuroscience
Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.
The Journal of clinical investigation
Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
The Journal of clinical investigation
Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
Neutrophil-related factors as biomarkers in EAE and MS.
The Journal of experimental medicine
Rumble JM,Huber AK,Krishnamoorthy G,Srinivasan A,Giles DA,Zhang X,Wang L,Segal BM
14-0112 was used in Flow cytometry/Cell sorting to provide evidence of neutrophil involvement in MS and the animal model EAE, and suggest neutrophil-related molecules as an alternative source of novel biomarkers and therapeutic targets in MS.
Mon Jan 12 00:00:00 EST 2015
TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.
The Journal of experimental medicine
Wu K,Byers DE,Jin X,Agapov E,Alexander-Brett J,Patel AC,Cella M,Gilfilan S,Colonna M,Kober DL,Brett TJ,Holtzman MJ
14-0112 was used in Flow cytometry/Cell sorting to define the link between viral infection and type 2 immune response in chronic respiratory disease, showing that expression of TREM2 in macrophages is required, particularly soluble TREM2, which prevents apoptosis of macrophages and leads to chronic inflammatory disease.
Mon May 04 00:00:00 EDT 2015
Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.
The Journal of experimental medicine
Ruppert R,Moser M,Sperandio M,Rognoni E,Orban M,Liu WH,Schulz AS,Oostendorp RA,Massberg S,Fässler R
14-0112 was used in Flow cytometry/Cell sorting to highlight a role for Kindlin-3 in the control of haematopoietic stem and progenitor cell homing function.
Mon Aug 24 00:00:00 EDT 2015
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.
Brain : a journal of neurology
Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN
Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.
Cancer research
Kratochvill F,Gratz N,Qualls JE,Van De Velde LA,Chi H,Kovarik P,Murray PJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Western Blot
Sat Aug 01 00:00:00 EDT 2015
The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
Genes & development
Miyazaki M,Miyazaki K,Chen S,Chandra V,Wagatsuma K,Agata Y,Rodewald HR,Saito R,Chang AN,Varki N,Kawamoto H,Murre C
14-0112 was used in Flow cytometry/Cell sorting to show that Id2 and Id3 suppress the development and expansion of innate variant follicular helper T cells.
Sun Feb 15 00:00:00 EST 2015
COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.
Proceedings of the National Academy of Sciences of the United States of America
Larsson K,Kock A,Idborg H,Arsenian Henriksson M,Martinsson T,Johnsen JI,Korotkova M,Kogner P,Jakobsson PJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Jun 30 00:00:00 EDT 2015
CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages.
Proceedings of the National Academy of Sciences of the United States of America
Zheng C,Yang Q,Xu C,Shou P,Cao J,Jiang M,Chen Q,Cao G,Han Y,Li F,Cao W,Zhang L,Zhang L,Shi Y,Wang Y
14-0112 was used in Blocking experiments to investigate the role of CD11b in obesity-associated inflammation.
Tue Dec 29 00:00:00 EST 2015
PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization.
Cancer immunology research
Rekoske BT,Smith HA,Olson BM,Maricque BB,McNeel DG
14-0112 was used in Flow cytometry/Cell sorting to determine that vaccines aimed at eliciting effector CD8(+) T cells may have improved function when combined with PD-1 pathway inhibitors.
Sat Aug 01 00:00:00 EDT 2015
Effect of a broad-specificity chemokine-binding protein on brain leukocyte infiltration and infarct development.
Stroke
Lee S,Chu HX,Kim HA,Real NC,Sharif S,Fleming SB,Mercer AA,Wise LM,Drummond GR,Sobey CG
14-0112 was used in Flow cytometry/Cell sorting to investigate whether post-stroke administration of a chemokine-binding protein, derived from the parapoxvirus bovine papular stomatitis virus, might reduce infiltration of leukocytes into the brain and therefore limit infarct development.
Sun Feb 01 00:00:00 EST 2015
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
PLoS biology
Gallego-Ortega D,Ledger A,Roden DL,Law AM,Magenau A,Kikhtyak Z,Cho C,Allerdice SL,Lee HJ,Valdes-Mora F,Herrmann D,Salomon R,Young AI,Lee BY,Sergio CM,Kaplan W,Piggin C,Conway JR,Rabinovich B,Millar EK,Oakes SR,Chtanova T,Swarbrick A,Naylor MJ,O'Toole S,Green AR,Timpson P,Gee JM,Ellis IO,Clark SJ,Ormandy CJ
14-0112 was used in Flow cytometry/Cell sorting to implicate ELF5 as a defining factor in the acquisition of the key aspects of the lethal phenotype in luminal A breast cancer.
Tue Dec 01 00:00:00 EST 2015
The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages.
eLife
Park C,Arthos J,Cicala C,Kehrl JH
14-0112 was used in Flow cytometry/Cell sorting to reveal a specialised lymph node antigen delivery system capable of delivering gp120 and other pathogen-derived glycoproteins to B cells.
Mon Aug 10 00:00:00 EDT 2015
IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production.
Mucosal immunology
Jung Y,Wen T,Mingler MK,Caldwell JM,Wang YH,Chaplin DD,Lee EH,Jang MH,Woo SY,Seoh JY,Miyasaka M,Rothenberg ME
14-0112 was used in Flow cytometry/Cell sorting to show that eosinophils are required for mucosal production of IgA and development of Peyer's patches in the gut.
Wed Jul 01 00:00:00 EDT 2015
Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases.
Breast cancer research : BCR
Tabariès S,Ouellet V,Hsu BE,Annis MG,Rose AA,Meunier L,Carmona E,Tam CE,Mes-Masson AM,Siegel PM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Fri Mar 27 00:00:00 EDT 2015
Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.
Glia
Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Aging-like changes in the transcriptome of irradiated microglia.
Glia
Li MD,Burns TC,Kumar S,Morgan AA,Sloan SA,Palmer TD
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Foxm1 regulates resolution of hyperoxic lung injury in newborns.
American journal of respiratory cell and molecular biology
Xia H,Ren X,Bolte CS,Ustiyan V,Zhang Y,Shah TA,Kalin TV,Whitsett JA,Kalinichenko VV
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that Foxm1 influences pulmonary inflammatory responses to hyperoxia, inhibiting neutrophil-derived enzymes and enhancing monocytic responses that limit alveolar injury and remodeling in neonatal lungs.
Fri May 01 00:00:00 EDT 2015
Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive.
PLoS pathogens
Sanin DE,Prendergast CT,Bourke CD,Mountford AP
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of skin CD4+ T cells in immune regulation after repeated pathogen exposure.
Fri May 01 00:00:00 EDT 2015
Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive.
PLoS pathogens
Sanin DE,Prendergast CT,Bourke CD,Mountford AP
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of skin CD4+ T cells in immune regulation after repeated pathogen exposure.
Fri May 01 00:00:00 EDT 2015
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
PLoS pathogens
Dalton JE,Glover AC,Hoodless L,Lim EK,Beattie L,Kirby A,Kaye PM
14-0112 was used in Flow cytometry/Cell sorting to investigate how Ntrk2 plays a role in the pathologic remodeling of the spleen that accompanies chronic infection.
Sun Feb 01 00:00:00 EST 2015
Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation.
PLoS pathogens
Sei JJ,Haskett S,Kaminsky LW,Lin E,Truckenmiller ME,Bellone CJ,Buller RM,Norbury CC
14-0112 was used in Flow cytometry/Cell sorting to suggest that direct antigen presentation is the dominant pathway in mice during mousepox.
Mon Jun 01 00:00:00 EDT 2015
Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma.
European journal of immunology
McAlees JW,Lajoie S,Dienger K,Sproles AA,Richgels PK,Yang Y,Khodoun M,Azuma M,Yagita H,Fulkerson PC,Wills-Karp M,Lewkowich IP
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of PD-1 family members in allergic asthma, showing differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis.
Wed Apr 01 00:00:00 EDT 2015
Cytokine-Mediated Activation of NK Cells during Viral Infection.
Journal of virology
Freeman BE,Raué HP,Hill AB,Slifka MK
14-0112 was used in Flow cytometry/Cell sorting to study how cytokines interact to regulate natural killer cell function during viral infection.
Sat Aug 01 00:00:00 EDT 2015
The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis.
Journal of virology
Donaldson DS,Else KJ,Mabbott NA
14-0112 was used in Immunohistochemistry on frozen tissues to demonstrate that the small intestinal GALT are the major early sites of prion accumulation and neuroinvasion after oral exposure in oral prion disease pathogenesis.
Tue Sep 01 00:00:00 EDT 2015
Myeloid heme oxygenase-1 promotes metastatic tumor colonization in mice.
Cancer science
Lin HH,Chiang MT,Chang PC,Chau LY
14-0112 was used in Immunofluorescence to demonstrate that heme oxygenase-1 impacts chemoattractant-induced myeloid cell migration by modulating p38 kinase signaling.
Sun Mar 01 00:00:00 EST 2015
Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models.
Molecular cancer therapeutics
Cuadrado-Castano S,Ayllon J,Mansour M,de la Iglesia-Vicente J,Jordan S,Tripathi S,García-Sastre A,Villar E
14-0112 was used in Flow cytometry/Cell sorting to demonstrate an augmented agent for cancer therapy which exploits the oncolytic properties of Newcastle disease virus.
Fri May 01 00:00:00 EDT 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950)
Biswas A,Bruder D,Wolf SA,Jeron A,Mack M,Heimesaat MM,Dunay IR
14-0112 was used in Flow cytometry/Cell sorting to indicate the critical importance of recruited Ly6C monocytes upon cerebral toxoplasmosis.
Wed Apr 01 00:00:00 EDT 2015
Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance.
Journal of immunology (Baltimore, Md. : 1950)
O'Hagan KL,Choi J,Pryshchep O,Chernoff J,Phee H
14-0112 was used in Flow cytometry/Cell sorting to show a novel role for the actin cytoskeletal remodeling protein, p21-activated kinase 2, in Treg development and homeostasis.
Sat Aug 15 00:00:00 EDT 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-0112-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 EDT 2015
Haploinsufficiency for Stard7 is associated with enhanced allergic responses in lung and skin.
Journal of immunology (Baltimore, Md. : 1950)
Yang L,Lewkowich I,Apsley K,Fritz JM,Wills-Karp M,Weaver TE
14-0112 was used in Flow cytometry/Cell sorting to determine whether loss of Stard7 expression promotes allergic responses, showing that haploinsufficiency for Stard7 is associated with enhanced allergic responses.
Mon Jun 15 00:00:00 EDT 2015
Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.
Journal of immunology (Baltimore, Md. : 1950)
Suryawanshi A,Manoharan I,Hong Y,Swafford D,Majumdar T,Taketo MM,Manicassamy B,Koni PA,Thangaraju M,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-0112 was used in Flow cytometry/Cell sorting to study the factors in the tissue microenvironment and signalling networks critical for programming dendritic cells to control chronic inflammation and promote tolerance, showing that Th1/Th17 responses are regulated by canonical Wnt signalling in dendritic cells and suppresses autoimmune neuroinflammation.
Wed Apr 01 00:00:00 EDT 2015
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.
Journal of immunology (Baltimore, Md. : 1950)
Ackermann JA,Nys J,Schweighoffer E,McCleary S,Smithers N,Tybulewicz VL
14-0112 was used in Flow cytometry/Cell sorting to define the contribution of Syk to B cell function.
Fri May 15 00:00:00 EDT 2015
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.
Journal of immunology (Baltimore, Md. : 1950)
Evonuk KS,Baker BJ,Doyle RE,Moseley CE,Sestero CM,Johnston BP,De Sarno P,Tang A,Gembitsky I,Hewett SJ,Weaver CT,Raman C,DeSilva TM
14-0112 was used in Flow cytometry/Cell sorting to investigate the link between inflammation and glutamate dysregulation in EAE, showing that inhibition of system Xc(-) transporter attenuates autoimmune inflammatory demyelination.
Wed Jul 15 00:00:00 EDT 2015
The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells.
Journal of cellular and molecular medicine
Ji J,Griffiths KL,Milburn PJ,Hirst TR,O'Neill HC
14-0112 was used in Magnetic cell separation to investigate the direct effect of intravenously administered EtxB on the size of the dendritic and myeloid cell populations in spleen.
Sat Aug 01 00:00:00 EDT 2015
Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy.
Journal of ethnopharmacology
Qu C,Li B,Lai Y,Li H,Windust A,Hofseth LJ,Nagarkatti M,Nagarkatti P,Wang XL,Tang D,Janicki JS,Tian X,Cui T
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that panaxynol-activated Nrf2 signalling is at least partly responsible for American ginseng-induced health benefit in the heart.
Sat Jun 20 00:00:00 EDT 2015
Piliation of Lactobacillus rhamnosus GG promotes adhesion, phagocytosis, and cytokine modulation in macrophages.
Applied and environmental microbiology
Vargas García CE,Petrova M,Claes IJ,De Boeck I,Verhoeven TL,Dilissen E,von Ossowski I,Palva A,Bullens DM,Vanderleyden J,Lebeer S
14-0112 was used in Blocking experiments to investigate the role of the SpaCBA pilus of L. rhamnosus GG in the interaction with macrophages in vitro by comparing the wild type with surface mutants.
Sun Mar 01 00:00:00 EST 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
IL-18 contributes to susceptibility to Leishmania amazonensis infection by macrophage-independent mechanisms.
Cytokine
Sousa LM,Carneiro MB,Dos Santos LM,Natale CC,Resende ME,Mosser DM,Vieira LQ
14-0112 was used in Flow cytometry/Cell sorting to investigate whether or not macrophages are involved in IL-18-mediated susceptibility to L. amazonensis.
Sat Aug 01 00:00:00 EDT 2015
Regulatory CD8(+)CD122 (+) T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting B-cells.
Metabolic brain disease
Bodhankar S,Chen Y,Lapato A,Vandenbark AA,Murphy SJ,Saugstad JA,Offner H
14-0112 was used in Flow cytometry/Cell sorting to demonstrate a major neuroprotective role for IL-10(+) B-cells in treating MCAO in male WT mice.
Sat Aug 01 00:00:00 EDT 2015
Intracellular Listeria monocytogenes comprises a minimal but vital fraction of the intestinal burden following foodborne infection.
Infection and immunity
Jones GS,Bussell KM,Myers-Morales T,Fieldhouse AM,Bou Ghanem EN,D'Orazio SE
14-0112 was used in Flow cytometry/Cell sorting to investigate how mouse-adapted and wild-type L. monocytogenes strains spread to the mesenteric lymph nodes in a foodborne model of listeriosis.
Sat Aug 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Mesenchymal stem cells can prevent alterations in behavior and neurogenesis induced by Aß25-35 administration.
Journal of molecular neuroscience : MN
Hamisha KN,Tfilin M,Yanai J,Turgeman G
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Wed Apr 01 00:00:00 EDT 2015
Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.
PloS one
Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue May 10 00:00:00 EDT 2016
Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.
PloS one
Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue May 10 00:00:00 EDT 2016
Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity.
PloS one
McMaster SR,Gabbard JD,Koutsonanos DG,Compans RW,Tripp RA,Tompkins SM,Kohlmeier JE
14-0112 was used in Flow cytometry/Cell sorting to quantify the H7N9 cross-reactive memory T cell reservoir in humans and mice previously exposed to common circulating influenza viruses.
Tue Jan 19 00:00:00 EST 2016
Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.
The Journal of biological chemistry
Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2015
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation.
Nature communications
Ryu JK,Petersen MA,Murray SG,Baeten KM,Meyer-Franke A,Chan JP,Vagena E,Bedard C,Machado MR,Rios Coronado PE,Prod'homme T,Charo IF,Lassmann H,Degen JL,Zamvil SS,Akassoglou K
14-0112 was used in Functional assays to investigate the mechanisms that drive immunological responses targeted to the CNS.
Thu Sep 10 00:00:00 EDT 2015
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Nature communications
Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Mar 20 00:00:00 EDT 2015
Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells.
Nature communications
Gao Y,Yang P,Shen H,Yu H,Song X,Zhang L,Zhang P,Cheng H,Xie Z,Hao S,Dong F,Ma S,Ji Q,Bartlow P,Ding Y,Wang L,Liu H,Li Y,Cheng H,Miao W,Yuan W,Yuan Y,Cheng T,Xie XQ
14-0112 was used in Flow cytometry/Cell sorting to investigate how putative small-molecule inhibitors for p18 protein are valuable for further dissecting the signalling pathways of stem cell self-renewal.
Wed Feb 18 00:00:00 EST 2015
Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
PloS one
Mandl M,Drechsler M,Jansen Y,Neideck C,Noels H,Faussner A,Soehnlein O,Weber C,Döring Y
14-0112 was used in Flow cytometry/Cell sorting to investigate how continuous diphtheria toxin-induced pDC depletion in Apoe-/- BDCA2-DTR mice receiving a high-fat diet (HFD) for 4 weeks did not alter lesion size or composition.
Sun May 08 00:00:00 EDT 2016
Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.
Nature communications
Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that ASXL1 truncations confer enhanced activity on the ASXL1-BAP1 complex.
Mon Jun 22 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.
Nature communications
Mackley EC,Houston S,Marriott CL,Halford EE,Lucas B,Cerovic V,Filbey KJ,Maizels RM,Hepworth MR,Sonnenberg GF,Milling S,Withers DR
14-0112 was used in Flow cytometry/Cell sorting to investigate whether group 3 innate lymphoid cells migrate from their mucosal and peripheral sites to local draining secondary lymphoid tissues.
Fri Jan 09 00:00:00 EST 2015
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates.
Scientific reports
Franken L,Klein M,Spasova M,Elsukova A,Wiedwald U,Welz M,Knolle P,Farle M,Limmer A,Kurts C
14-0112 was used in Flow cytometry/Cell sorting to elucidate the intrinsic superparamagnetic nature of splenic red pulp macrophages and their effect on magnetic cell isolates.
Tue Aug 11 00:00:00 EDT 2015
Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype.
Journal of hematology & oncology
Xiao G,Wang X,Sheng J,Lu S,Yu X,Wu JD
14-0112 was used in Flow cytometry/Cell sorting to report a novel mechanism by which soluble MIC imposes an immunosuppressive effect on host immunity and the tumour microenvironment.
Fri Feb 20 00:00:00 EST 2015
Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas.
Oncoimmunology
Ahn B,Kohanbash G,Ohkuri T,Kosaka A,Chen X,Ikeura M,Wang TC,Okada H
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of HDC in the glioma microenvironment via maturation of myeloid cells and resulting activation of CD8(+) T cells.
Sun Nov 01 00:00:00 EDT 2015
Deficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus-Induced Autoimmunity.
mBio
Chastain EM,Getts DR,Miller SD
14-0112 was used in Flow cytometry/Cell sorting to determine that disease-susceptible SJL/J mice lacked a unique innate immune population, which plays a role in early CNS virus clearance.
Tue Aug 04 00:00:00 EDT 2015
Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels.
PloS one
Watzlawick R,Kenngott EE,Liu FD,Schwab JM,Hamann A
14-0112 was used in Flow cytometry/Cell sorting to determine the role of IL-27 in innate immune responses.
Tue May 24 00:00:00 EDT 2016
Aquaporin-9-expressing neutrophils are required for the establishment of contact hypersensitivity.
Scientific reports
Moniaga CS,Watanabe S,Honda T,Nielsen S,Hara-Chikuma M
14-0112 was used in Flow cytometry/Cell sorting to suggest that AQP9 is required for the development of sensitisation during cutaneous acquired immune responses via regulating neutrophil function.
Thu Oct 22 00:00:00 EDT 2015
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Nature communications
Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.
Fri Apr 10 00:00:00 EDT 2015
Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease.
PloS one
Galvani RG,Lemos R,Areal RB,Salvador PA,Zamboni DS,Wanderley JL,Bonomo A
14-0112 was used in Magnetic cell separation to investigate the exact cause of death in graft versus host disease, showing that disease severity and mortality can be independently regulated.
Mon Oct 19 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Alendronate inhalation ameliorates elastase-induced pulmonary emphysema in mice by induction of apoptosis of alveolar macrophages.
Nature communications
Ueno M,Maeno T,Nishimura S,Ogata F,Masubuchi H,Hara K,Yamaguchi K,Aoki F,Suga T,Nagai R,Kurabayashi M
14-0112 was used in Flow cytometry/Cell sorting to demonstrate the therapeutic potential of alendronate administration for the treatment of emphysema.
Tue Mar 10 00:00:00 EDT 2015
Dendritic Cell Protection from Cisplatin Nephrotoxicity Is Independent of Neutrophils.
Toxins
Tadagavadi RK,Gao G,Wang WW,Gonzalez MR,Reeves WB
14-0112 was used in Flow cytometry/Cell sorting to investigate the kinetics of neutrophil infiltration into kidneys and their role in cisplatin-mediated acute kidney injury.
Wed Aug 19 00:00:00 EDT 2015
Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis.
Scientific reports
Casiraghi C,Márquez AC,Shanina I,Horwitz MS
14-0112 was used in Flow cytometry/Cell sorting to investigate the cause of enhanced experimental autoimmune encephalomyelitis following infection with murine γ-herpesvirus 68.
Thu Sep 10 00:00:00 EDT 2015
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Thu Feb 27 00:00:00 EST 2014
RNA viruses can hijack vertebrate microRNAs to suppress innate immunity.
Nature
Trobaugh DW,Gardner CL,Sun C,Haddow AD,Wang E,Chapnik E,Mildner A,Weaver SC,Ryman KD,Klimstra WB
14-0112 was used in Immunocytochemistry to study the mechanism by which haematopoietic-cell-specific miR-142-3p potently restricts the replication of the mosquito-borne North American eastern equine encephalitis virus in myeloid-lineage cells.
Thu Feb 13 00:00:00 EST 2014
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Nature
Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 25 00:00:00 EDT 2014
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.
Cell metabolism
Lee S,Lee HC,Kwon YW,Lee SE,Cho Y,Kim J,Lee S,Kim JY,Lee J,Yang HM,Mook-Jung I,Nam KY,Chung J,Lazar MA,Kim HS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Tue Mar 04 00:00:00 EST 2014
Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.
Cell metabolism
Gordts PLSM,Foley EM,Lawrence R,Sinha R,Lameda-Diaz C,Deng L,Nock R,Glass CK,Erbilgin A,Lusis AJ,Witztum JL,Esko JD
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of heparan sulfate proteoglycans in atherogenesis, showing that reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity.
Tue Nov 04 00:00:00 EST 2014
A role for the ITAM signaling module in specifying cytokine-receptor functions.
Nature immunology
Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Nature immunology
Huang SC,Everts B,Ivanova Y,O'Sullivan D,Nascimento M,Smith AM,Beatty W,Love-Gregory L,Lam WY,O'Neill CM,Yan C,Du H,Abumrad NA,Urban JF,Artyomov MN,Pearce EL,Pearce EJ
14-0112 was used in Flow cytometry/Cell sorting to delineate a critical role for cell-intrinsic lysosomal lipolysis in M2 activation.
Mon Sep 01 00:00:00 EDT 2014
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.
Nature immunology
Khare S,Ratsimandresy RA,de Almeida L,Cuda CM,Rellick SL,Misharin AV,Wallin MC,Gangopadhyay A,Forte E,Gottwein E,Perlman H,Reed JC,Greaves DR,Dorfleutner A,Stehlik C
14-0112 was used in Flow cytometry/Cell sorting to study the molecular mechanisms regulating the activation of the innate immune response to viral DNA.
Tue Apr 01 00:00:00 EDT 2014
In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice.
Blood
Derderian SC,Togarrati PP,King C,Moradi PW,Reynaud D,Czechowicz A,Weissman IL,MacKenzie TC
14-0112 was used in Flow cytometry/Cell sorting to develop a successful foetal conditioning strategy associated with minimal toxicity.
Thu Aug 07 00:00:00 EDT 2014
Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium.
The Journal of clinical investigation
Moding EJ,Lee CL,Castle KD,Oh P,Mao L,Zha S,Min HD,Ma Y,Das S,Kirsch DG
14-0112 was used in Immunofluorescence to determine that endothelial cells must progress through the cell cycle in order to be radiosensitized by Atm deletion.
Fri Aug 01 00:00:00 EDT 2014
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
14-0112 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.
The Journal of clinical investigation
Bhadra R,Moretto MM,Castillo JC,Petrovas C,Ferrando-Martinez S,Shokal U,Leal M,Koup RA,Eleftherianos I,Khan IA
14-0112 was used in Flow cytometry/Cell sorting to investigate the progressive loss of CD8+ T cell polyfunctionality during aging, using animals challenged with the obligate intracellular pathogen Encephalitozoon cuniculi.
Sun Jun 01 00:00:00 EDT 2014
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection.
The Journal of experimental medicine
Penaloza-MacMaster P,Kamphorst AO,Wieland A,Araki K,Iyer SS,West EE,O'Mara L,Yang S,Konieczny BT,Sharpe AH,Freeman GJ,Rudensky AY,Ahmed R
14-0112 was used in Flow cytometry/Cell sorting to investigate a role for T reg cells in exhaustion of virus-specific CD8 T cells.
Mon Aug 25 00:00:00 EDT 2014
The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.
The Journal of experimental medicine
Male V,Nisoli I,Kostrzewski T,Allan DS,Carlyle JR,Lord GM,Wack A,Brady HJ
14-0112 was used in Flow cytometry/Cell sorting to propose that E4bp4 is required for commitment to the NK lineage and can promote NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.
Mon Apr 07 00:00:00 EDT 2014
Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.
The Journal of experimental medicine
Ma JS,Sasai M,Ohshima J,Lee Y,Bando H,Takeda K,Yamamoto M
14-0112 was used in Flow cytometry/Cell sorting to suggest that GRA6-dependent NFAT4 activation is required for Toxoplasma gondii manipulation of host immune responses.
Mon Sep 22 00:00:00 EDT 2014
Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
The Journal of experimental medicine
Wu L,Ong S,Talor MV,Barin JG,Baldeviano GC,Kass DA,Bedja D,Zhang H,Sheikh A,Margolick JB,Iwakura Y,Rose NR,Ciháková D
14-0112 was used in Immunofluorescence to show a novel pathway connecting IL-17A, cardiac fibroblasts, GM-CSF, and heart-infiltrating myeloid cells with the pathogenesis of DCMi.
Mon Jun 30 00:00:00 EDT 2014
Progressive replacement of embryo-derived cardiac macrophages with age.
The Journal of experimental medicine
Molawi K,Wolf Y,Kandalla PK,Favret J,Hagemeyer N,Frenzel K,Pinto AR,Klapproth K,Henri S,Malissen B,Rodewald HR,Rosenthal NA,Bajenoff M,Prinz M,Jung S,Sieweke MH
14-0112 was used in Flow cytometry/Cell sorting to report that the embryo-derived population of cardiac macrophages is progressively substituted for monocyte-derived macrophages within the first weeks after birth.
Mon Oct 20 00:00:00 EDT 2014
Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression.
Biomaterials
Gower RM,Boehler RM,Azarin SM,Ricci CF,Leonard JN,Shea LD
14-0112 was used in Flow cytometry/Cell sorting to investigate if lentiviral IL-10 gene delivery can reduce inflammation following biomaterial implantation.
Sat Feb 01 00:00:00 EST 2014
Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes.
EMBO molecular medicine
Diana J,Lehuen A
14-0112 was used in Flow cytometry/Cell sorting to determine the cellular and molecular mechanisms leading to the recruitment of neutrophils in the pancreatic islets of non-obese diabetic mice.
Fri Aug 01 00:00:00 EDT 2014
Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer.
Autophagy
Guo W,Sun Y,Liu W,Wu X,Guo L,Cai P,Wu X,Wu X,Shen Y,Shu Y,Gu Y,Xu Q
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Sun Jun 01 00:00:00 EDT 2014
RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma.
Cancer research
Chen X,Zhang L,Zhang IY,Liang J,Wang H,Ouyang M,Wu S,da Fonseca ACC,Weng L,Yamamoto Y,Yamamoto H,Natarajan R,Badie B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Dec 15 00:00:00 EST 2014
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Cancer research
Ho PC,Meeth KM,Tsui YC,Srivastava B,Bosenberg MW,Kaech SM
14-0112 was used in Flow cytometry/Cell sorting to investigate whether B-Raf(V600E) inhibitors promote tumor regression with the help of host immunity, showing that they rely on signaling by CD40L and IFNγ.
Sun Jun 15 00:00:00 EDT 2014
Murine CD27(-) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages.
Proceedings of the National Academy of Sciences of the United States of America
Rei M,Gonçalves-Sousa N,Lança T,Thompson RG,Mensurado S,Balkwill FR,Kulbe H,Pennington DJ,Silva-Santos B
14-0112 was used in Flow cytometry/Cell sorting to characterise the role of tumour-associated γδ T cells on disease development using a model peritoneal/ovarian cancer cell line.
Tue Aug 26 00:00:00 EDT 2014
Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America
Wang L,Le Mercier I,Putra J,Chen W,Liu J,Schenk AD,Nowak EC,Suriawinata AA,Li J,Noelle RJ
14-0112 was used in Flow cytometry/Cell sorting to study the effect of VISTA genetic deficiency on T-cell-mediated inflammation, showing that the threshold for activation was lowered and that there was increased susceptibility to autoimmunity.
Tue Oct 14 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Tue Aug 12 00:00:00 EDT 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
Science signaling
Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Tue Aug 12 00:00:00 EDT 2014
Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term.
Diabetes
Takiishi T,Ding L,Baeke F,Spagnuolo I,Sebastiani G,Laureys J,Verstuyf A,Carmeliet G,Dotta F,Van Belle TL,Gysemans CA,Mathieu C
14-0112 was used in Flow cytometry/Cell sorting to investigate the effect of vitamin D3 administration during different periods of life on diabetes prevention in NOD mice.
Sun Jun 01 00:00:00 EDT 2014
Distinct progenitor origin distinguishes a lineage of dendritic-like cells in spleen.
Frontiers in immunology
Petvises S,O'Neill HC
14-0112 was used in Flow cytometry/Cell sorting to study how a lineage of dendritic-like cells in the spleen are distinguished by distinct progenitor origins.
Wed Jan 15 00:00:00 EST 2014
Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.
Glia
Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosis.
The Journal of infectious diseases
Vogelzang A,Perdomo C,Zedler U,Kuhlmann S,Hurwitz R,Gengenbacher M,Kaufmann SH
14-0112 was used in Flow cytometry/Cell sorting to investigate the T-cell population required for recombinant Bacillus Calmette-Guérin δureC::hly vaccine's enhanced protection against tuberculosis.
Mon Dec 15 00:00:00 EST 2014
Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense.
PLoS pathogens
Verma S,Loewendorf A,Wang Q,McDonald B,Redwood A,Benedict CA
14-0112 was used in Flow cytometry/Cell sorting to highlight the critical importance for CMV to have evolved a strategy to inhibit TRAIL-DR signaling to thwart NK-mediated defenses.
Fri Aug 01 00:00:00 EDT 2014
Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection.
PLoS pathogens
Whitney PG,Bär E,Osorio F,Rogers NC,Schraml BU,Deddouche S,LeibundGut-Landmann S,Reis e Sousa C
14-0112 was used in Flow cytometry/Cell sorting to study the contribution of a specific signalling pathway involved in fungal recognition by dendritic cells during immune responses to fungal pathogens.
Tue Jul 01 00:00:00 EDT 2014
Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection.
PLoS pathogens
Whitney PG,Bär E,Osorio F,Rogers NC,Schraml BU,Deddouche S,LeibundGut-Landmann S,Reis e Sousa C
14-0112 was used in Flow cytometry/Cell sorting to study the contribution of a specific signalling pathway involved in fungal recognition by dendritic cells during immune responses to fungal pathogens.
Tue Jul 01 00:00:00 EDT 2014
Sepsis-induced potentiation of peritoneal macrophage migration is mitigated by programmed cell death receptor-1 gene deficiency.
Journal of innate immunity
Ayala A,Elphick GF,Kim YS,Huang X,Carreira-Rosario A,Santos SC,Shubin NJ,Chen Y,Reichner J,Chung CS
14-0112 was used in Flow cytometry/Cell sorting to investigate the effect of programmed cell death receptor-1 in mediating aspects of innate macrophage immune dysfunction during sepsis.
Mon May 11 00:00:00 EDT 2015
A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.
Development (Cambridge, England)
Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Jun 01 00:00:00 EDT 2014
Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Howerton AR,Roland AV,Bale TL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Wed May 21 00:00:00 EDT 2014
Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
European journal of immunology
Mayer CT,Ghorbani P,Kühl AA,Stüve P,Hegemann M,Berod L,Gershwin ME,Sparwasser T
14-0112 was used in Flow cytometry/Cell sorting to study the mechanisms underlying why regulatory T cell-depletion fails to cause autoimmunity in adult Depletion of REGulatory T cells mice.
Wed Oct 01 00:00:00 EDT 2014
MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve Toll-like receptor 2.
Journal of virology
Davies ML,Sei JJ,Siciliano NA,Xu RH,Roscoe F,Sigal LJ,Eisenlohr LC,Norbury CC
14-0112 was used in Flow cytometry/Cell sorting to investigate the ability of the innate sensing molecule Toll-like receptor 2 and the signalling molecule MyD88 to influence the innate and adaptive immune response to vaccinia virus following systemic or dermal infection.
Sat Mar 01 00:00:00 EST 2014
Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology
Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Apr 15 00:00:00 EDT 2014
Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology
Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Apr 15 00:00:00 EDT 2014
Neutrophils mediate edema formation but not mechanical allodynia during zymosan-induced inflammation.
Journal of leukocyte biology
Suo J,Linke B,Meyer dos Santos S,Pierre S,Stegner D,Zhang DD,Denis CV,Geisslinger G,Nieswandt B,Scholich K
14-0112 was used in Blocking experiments to study the contribution of neutrophils to zymosan-induced inflammatory pain.
Tue Jul 01 00:00:00 EDT 2014
Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii.
Immunology and cell biology
Han SJ,Melichar HJ,Coombes JL,Chan SW,Koshy AA,Boothroyd JC,Barton GM,Robey EA
14-0112 was used in Flow cytometry/Cell sorting to show that inflammatory monocytes, but not neutrophils, produce IFN-β in response to T. gondii infection.
Sat Nov 01 00:00:00 EDT 2014
Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and γδ T cells.
Immunology and cell biology
Do JS,Visperas A,Freeman ML,Iwakura Y,Oukka M,Min B
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that T-cell colitogenicity is achieved through multiple processes, offering a therapeutic rationale by intervening these pathways.
Wed Jan 01 00:00:00 EST 2014
CX3CR1 delineates temporally and functionally distinct subsets of myeloid-derived suppressor cells in a mouse model of ovarian cancer.
Immunology and cell biology
Hart KM,Usherwood EJ,Berwin BL
14-0112 was used in Flow cytometry/Cell sorting to investigate a novel nongranulocytic CX3CR1-negative myeloid population.
Tue Jul 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Manoharan I,Hong Y,Suryawanshi A,Angus-Hill ML,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-0112 was used in Flow cytometry/Cell sorting to investigate how diametric signals from the pathogen recognition receptors TLR2 and dectin-1 are coordinated in dendritic cells to regulate or incite immunity.
Wed Oct 15 00:00:00 EDT 2014
The DC-HIL/syndecan-4 pathway regulates autoimmune responses through myeloid-derived suppressor cells.
Journal of immunology (Baltimore, Md. : 1950)
Chung JS,Tamura K,Akiyoshi H,Cruz PD,Ariizumi K
14-0112 was used in Flow cytometry/Cell sorting to investigate the mechanisms of regulation of autoimmune responses in experimental autoimmune encephalomyelitis.
Sat Mar 15 00:00:00 EDT 2014
Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression.
Journal of immunology (Baltimore, Md. : 1950)
Arina A,Schreiber K,Binder DC,Karrison TG,Liu RB,Schreiber H
14-0112 was used in Flow cytometry/Cell sorting to study the effect of adoptively transferred immune T cells in the presence of MDSCs and TAMs on established tumours, showing that they are eradicated.
Sat Feb 01 00:00:00 EST 2014
Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.
Journal of immunology (Baltimore, Md. : 1950)
El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Jul 15 00:00:00 EDT 2014
IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major.
Journal of immunology (Baltimore, Md. : 1950)
Akbari M,Honma K,Kimura D,Miyakoda M,Kimura K,Matsuyama T,Yui K
14-0112 was used in Flow cytometry/Cell sorting to investigate the roles of the transcription factor IRF4 in dendritic cells and macrophages in vivo.
Sat Mar 01 00:00:00 EST 2014
B cell-specific loss of Lyn kinase leads to autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Lamagna C,Hu Y,DeFranco AL,Lowell CA
14-0112-82 was used in Flow Cytometry to demonstrate that B cell-intrinsic Lyn-dependent signalling pathways regulate B cell homeostasis and activation.
Sat Feb 01 00:00:00 EST 2014
IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Lajoie S,Lewkowich I,Herman NS,Sproles A,Pesce JT,Wynn TA,Grusby MJ,Hamid Q,Wills-Karp M
14-0112 was used in Flow cytometry/Cell sorting to suggest that IL-21 plays an important role in the allergic diathesis by enhancing Th2 cytokine production through multiple mechanisms.
Tue Jul 01 00:00:00 EDT 2014
A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells.
Journal of cell science
Gawden-Bone C,West MA,Morrison VL,Edgar AJ,McMillan SJ,Dill BD,Trost M,Prescott A,Fagerholm SC,Watts C
14-0112 was used in Flow cytometry/Cell sorting to assess the contribution of integrins to the function and maintenance of podosomes.
Wed Oct 01 00:00:00 EDT 2014
Natural history of tumor growth and immune modulation in common spontaneous murine mammary tumor models.
Breast cancer research and treatment
Gad E,Rastetter L,Slota M,Koehnlein M,Treuting PM,Dang Y,Stanton S,Disis ML
14-0112 was used in Flow cytometry/Cell sorting to evaluate the relationship between growth rates of tumours in common spontaneous mammary tumor models and immune biomarkers evaluated in the tumour and blood.
Mon Dec 01 00:00:00 EST 2014
Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics.
Experimental gerontology
Goenka R,Scholz JL,Naradikian MS,Cancro MP
14-0112 was used in Flow cytometry/Cell sorting to study how age influences the overall germinal centre reaction during a primary immune response to a thymus-dependent antigen.
Sun Jun 01 00:00:00 EDT 2014
Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice.
Metabolic brain disease
Bodhankar S,Chen Y,Vandenbark AA,Murphy SJ,Offner H
14-0112 was used in Flow cytometry/Cell sorting to investigate the beneficial immunoregulatory effects of IL-10-producing B-cell stroke treatment in mice.
Sat Mar 01 00:00:00 EST 2014
Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection.
Infection and immunity
Ibrahim MK,Barnes JL,Osorio EY,Anstead GM,Jimenez F,Osterholzer JJ,Travi BL,Ahuja SS,White AC,Melby PC
14-0112 was used in Flow cytometry/Cell sorting to study populations of resident dendritic cells and migratory dermal dendritic cells in the skin-draining lymph nodes of L. donovani-infected malnourished mice.
Fri Aug 01 00:00:00 EDT 2014
Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages.
Journal of neuroimmunology
Carvalho da Fonseca AC,Wang H,Fan H,Chen X,Zhang I,Zhang L,Lima FR,Badie B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Sep 15 00:00:00 EDT 2014
Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis.
Journal of inflammation research
Yoo J,Manicone AM,McGuire JK,Wang Y,Parks WC
14-0112 was used in Immunofluorescence to reveal a mouse model of atopic dermatitis that reveals novel insights into the pathogenesis of this complex disease.
Thu Mar 27 00:00:00 EDT 2014
Protective immunity against lethal F. tularensis holarctica LVS provided by vaccination with selected novel CD8+ T cell epitopes.
PloS one
Rotem S,Cohen O,Bar-Haim E,Bar-On L,Ehrlich S,Shafferman A
14-0112 was used in Flow cytometry/Cell sorting to demonstrate a novel method for bacterial clearance involving the induction of an immune response to specific pathogenic epitopes.
Wed Sep 10 00:00:00 EDT 2014
Identification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cells.
PloS one
von Buttlar H,Siegemund S,Büttner M,Alber G
14-0112 was used in an ELISA assay to identify endosomal TLR9 as PPVO-sensing receptor in pDC.
Tue Nov 10 00:00:00 EST 2015
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
Nature communications
Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Oct 28 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
14-0112 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity.
PloS one
Leigh ND,Bian G,Ding X,Liu H,Aygun-Sunar S,Burdelya LG,Gudkov AV,Cao X
14-0112 was used in Flow cytometry/Cell sorting to assess the immunogenic capabilities of CBLB502, a toll-like receptor 5 agonist.
Wed Sep 17 00:00:00 EDT 2014
Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming.
Nature communications
Harland KL,Day EB,Apte SH,Russ BE,Doherty PC,Turner SJ,Kelso A
14-0112 was used in Flow cytometry/Cell sorting to study whether epigenetic modifications affecting T-cells persist following adoptive transfer of the cells.
Fri Mar 28 00:00:00 EDT 2014
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Jun 26 00:00:00 EDT 2014
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.
PloS one
May SL,Zhou Q,Lewellen M,Carter CM,Coffey D,Highfill SL,Bucher CM,Matise I,Morse HC,O'Sullivan MG,Schutten M,Johnson C,Bellgrau D,Blazar BR,Modiano JF
14-0112 was used in Flow cytometry/Cell sorting to study how Nfatc2 and Tob1 are non-redundant regulators of lymphocyte homeostasis.
Mon Oct 19 00:00:00 EDT 2015
Activated macrophage survival is coordinated by TAK1 binding proteins.
PloS one
Mihaly SR,Morioka S,Ninomiya-Tsuji J,Takaesu G
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of TAB1 and TAB2 in macrophage survival.
Fri Jan 16 00:00:00 EST 2015
Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.
Cancer prevention research (Philadelphia, Pa.)
Hiramoto K,Satoh H,Suzuki T,Moriguchi T,Pi J,Shimosegawa T,Yamamoto M
14-0112 was used in Flow cytometry/Cell sorting to investigate whether cellular antioxidant defence systems in myeloid lineage cells plays indispensable roles for metastatic cancer progression.
Fri Aug 01 00:00:00 EDT 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.
PloS one
Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2015
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Feb 14 00:00:00 EST 2014
Intravenous immunoglobulin (IVIg) provides protection against endothelial cell dysfunction and death in ischemic stroke.
Experimental & translational stroke medicine
Widiapradja A,Santro T,Basta M,Sobey CG,Manzanero S,Arumugam TV
14-0112 was used in Flow cytometry/Cell sorting to study how intravenous immunoglobulin protects endothelial cells from ischaemic insult, supporting its use as a pharmacological intervention for stroke therapy.
Thu Jul 03 00:00:00 EDT 2014
RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Nature
Lukens JR,Vogel P,Johnson GR,Kelliher MA,Iwakura Y,Lamkanfi M,Kanneganti TD
14-0112 was used in Flow cytometry/Cell sorting to investigate how mutations in SHP-1 causes inflammatory disease, showing that RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Thu Jun 13 00:00:00 EDT 2013
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
Nature
Florian MC,Nattamai KJ,Dörr K,Marka G,Uberle B,Vas V,Eckl C,Andrä I,Schiemann M,Oostendorp RA,Scharffetter-Kochanek K,Kestler HA,Zheng Y,Geiger H
14-0112 was used in Immunocytochemistry to evaluate the role of Wnt signalling in the ageing of haematopoietic stem cells in mice.
Thu Nov 21 00:00:00 EST 2013
T cell factor 1 is required for group 2 innate lymphoid cell generation.
Immunity
Yang Q,Monticelli LA,Saenz SA,Chi AW,Sonnenberg GF,Tang J,De Obaldia ME,Bailis W,Bryson JL,Toscano K,Huang J,Haczku A,Pear WS,Artis D,Bhandoola A
14-0112 was used in Flow cytometry/Cell sorting to study group 2 innate lymphoid cell development.
Thu Apr 18 00:00:00 EDT 2013
Anatomically restricted synergistic antiviral activities of innate and adaptive immune cells in the skin.
Cell host & microbe
Hickman HD,Reynoso GV,Ngudiankama BF,Rubin EJ,Magadán JG,Cush SS,Gibbs J,Molon B,Bronte V,Bennink JR,Yewdell JW
14-0112 was used in Flow cytometry/Cell sorting to explore the spatiotemporal organization between antiviral immune cells and vaccinia virus-infected murine cells.
Wed Feb 13 00:00:00 EST 2013
Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection.
Cell host & microbe
Jordan S,Ruzsics Z,Mitrović M,Baranek T,Arapović J,Krmpotić A,Vivier E,Dalod M,Jonjić S,Dölken L,Koszinowski UH
14-0112 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms of extramedullary hematopoiesis.
Wed May 15 00:00:00 EDT 2013
Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells.
Nature immunology
Cohen NR,Brennan PJ,Shay T,Watts GF,Brigl M,Kang J,Brenner MB
14-0112 was used in Flow cytometry/Cell sorting to profile gene expression in invariant natural killer T cells during ontogeny and in peripheral subsets.
Tue Jan 01 00:00:00 EST 2013
Nrf2 regulates haematopoietic stem cell function.
Nature cell biology
Tsai JJ,Dudakov JA,Takahashi K,Shieh JH,Velardi E,Holland AM,Singer NV,West ML,Smith OM,Young LF,Shono Y,Ghosh A,Hanash AM,Tran HT,Moore MA,van den Brink MR
14-0112 was used in Flow cytometry/Cell sorting to investigate the link between Nrf2 and CXCR4, thought to partially contribute to the maintenance of haematopoietic stem cell function.
Fri Mar 01 00:00:00 EST 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1.
Blood
Yoshida A,Kato JY,Nakamae I,Yoneda-Kato N
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of COP1 in tumourigenesis.
Thu Sep 05 00:00:00 EDT 2013
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
14-0112-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 EDT 2013
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood
Singh RP,Franke K,Kalucka J,Mamlouk S,Muschter A,Gembarska A,Grinenko T,Willam C,Naumann R,Anastassiadis K,Stewart AF,Bornstein S,Chavakis T,Breier G,Waskow C,Wielockx B
14-0112 was used in Flow cytometry/Cell sorting to study the role of PHD2 in HSC compartment maintenance.
Thu Jun 27 00:00:00 EDT 2013
Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.
The Journal of clinical investigation
Kansara M,Leong HS,Lin DM,Popkiss S,Pang P,Garsed DW,Walkley CR,Cullinane C,Ellul J,Haynes NM,Hicks R,Kuijjer ML,Cleton-Jansen AM,Hinds PW,Smyth MJ,Thomas DM
14-0112 was used in Flow cytometry/Cell sorting to indicate that overcoming the immune response to senescence is a rate-limiting step in the formation of IR-induced osteosarcoma.
Sun Dec 01 00:00:00 EST 2013
MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.
The Journal of experimental medicine
Baba T,Naka K,Morishita S,Komatsu N,Hirao A,Mukaida N
14-0112 was used in Flow cytometry/Cell sorting to investigate the interaction between leukaemia-initiating cells and normal hematopoietic cells at the early phase of chronic myeloid leukaemia, showing MIP-1α/CCL3-mediated maintenance of initiating cells.
Mon Nov 18 00:00:00 EST 2013
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
The Journal of experimental medicine
Gao X,Johnson KD,Chang YI,Boyer ME,Dewey CN,Zhang J,Bresnick EH
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of Gata2 cis-element in generation of hematopoietic stem cells.
Mon Dec 16 00:00:00 EST 2013
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
14-0112 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 EST 2013
S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.
Clinical cancer research : an official journal of the American Association for Cancer Research
Wang H,Zhang L,Zhang IY,Chen X,Da Fonseca A,Wu S,Ren H,Badie S,Sadeghi S,Ouyang M,Warden CD,Badie B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Jul 15 00:00:00 EDT 2013
A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.
Developmental cell
Zhang Y,Tang W,Zhang H,Niu X,Xu Y,Zhang J,Gao K,Pan W,Boggon TJ,Toomre D,Min W,Wu D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Oct 28 00:00:00 EDT 2013
Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment.
Cancer research
Baird JR,Fox BA,Sanders KL,Lizotte PH,Cubillos-Ruiz JR,Scarlett UK,Rutkowski MR,Conejo-Garcia JR,Fiering S,Bzik DJ
14-0112 was used in Flow cytometry/Cell sorting to establish that cps preferentially invades tumour-associated antigen-presenting cells and restores their ability to trigger potent anti-tumour CD8(+) T-cell responses.
Mon Jul 01 00:00:00 EDT 2013
Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.
Proceedings of the National Academy of Sciences of the United States of America
Coombes JL,Charsar BA,Han SJ,Halkias J,Chan SW,Koshy AA,Striepen B,Robey EA
14-0112 was used in Flow cytometry/Cell sorting to explore the parasite-host interaction between Toxoplasma gondii and intestinal immune cells.
Tue May 21 00:00:00 EDT 2013
Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice.
Arteriosclerosis, thrombosis, and vascular biology
Ju X,Ijaz T,Sun H,Ray S,Lejeune W,Lee C,Recinos A,Guo DC,Milewicz DM,Tilton RG,Brasier AR
14-0112 was used in Flow cytometry/Cell sorting to suggest that the Th17-IL-17 axis is an important effector arm of Ang II-mediated vascular inflammation.
Mon Jul 01 00:00:00 EDT 2013
Activator protein-2α mediates carbon monoxide-induced stromal cell-derived factor-1α expression and vascularization in ischemic heart.
Arteriosclerosis, thrombosis, and vascular biology
Lin HH,Chen YH,Chiang MT,Huang PL,Chau LY
14-0112 was used in Immunohistochemistry to demonstrate that AKT-dependent upregulation of AP-2α is essential for CO-induced SDF-1α expression and myocardial repair after ischemic injury.
Mon Apr 01 00:00:00 EDT 2013
Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation.
eLife
Kerenyi MA,Shao Z,Hsu YJ,Guo G,Luc S,O'Brien K,Fujiwara Y,Peng C,Nguyen M,Orkin SH
14-0112 was used in Flow cytometry/Cell sorting to study how Lsd1-mediated concurrent repression of enhancer and promoter activity of stem and progenitor cell genes is a pivotal epigenetic mechanism required for proper hematopoietic maturation.
Tue Jun 18 00:00:00 EDT 2013
MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy.
eLife
Heinrichs S,Conover LF,Bueso-Ramos CE,Kilpivaara O,Stevenson K,Neuberg D,Loh ML,Wu WS,Rodig SJ,Garcia-Manero G,Kantarjian HM,Look AT
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that low MYBL2 activity is the underlying cause of the expansion of haematopoietic progenitors in a large fraction of myeloid malignancies.
Tue Jul 16 00:00:00 EDT 2013
Klf10 inhibits IL-12p40 production in macrophage colony-stimulating factor-induced mouse bone marrow-derived macrophages.
European journal of immunology
Zhang W,Wang X,Xia X,Liu X,Suo S,Guo J,Li M,Cao W,Cai Z,Hui Z,Subramaniam M,Spelsberg TC,Wang J,Wang L
14-0112 was used in Flow cytometry/Cell sorting to identify Klf10 as a transcription factor that regulates the expression of IL-12p40 in bone marrow-derived macrophages.
Tue Jan 01 00:00:00 EST 2013
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.
Journal of lipid research
Camacho M,Dilmé J,Solà-Villà D,Rodríguez C,Bellmunt S,Siguero L,Alcolea S,Romero JM,Escudero JR,Martínez-González J,Vila L
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Sun Dec 01 00:00:00 EST 2013
Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection.
Journal of virology
Trujillo JA,Fleming EL,Perlman S
14-0112 was used in Flow cytometry/Cell sorting to examine the role of CCL2 during virus infection, showing that CCL2 expression in the CNS results in a dysregulated immune response after coronavirus infection.
Fri Mar 01 00:00:00 EST 2013
Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal.
Stem cells (Dayton, Ohio)
Jeannet R,Cai Q,Liu H,Vu H,Kuo YH
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of activated leukocyte cell adhesion molecule in hematopoietic stem cell differentiation and self-renewal using an Alcam-null mouse model.
Fri Mar 01 00:00:00 EST 2013
ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Zumwalde NA,Domae E,Mescher MF,Shimizu Y
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that during CD8 T cell activation, the T cell clustering mechanism allows for continued proliferation of T cells, and regulates CD8 T cell effector function and differentiation.
Tue Oct 01 00:00:00 EDT 2013
Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice.
Journal of immunology (Baltimore, Md. : 1950)
Avalos AM,Kirak O,Oelkers JM,Pils MC,Kim YM,Ottinger M,Jaenisch R,Ploegh HL,Brinkmann MM
14-0112 was used in Flow cytometry/Cell sorting to examine the intracellular behavior of TLR9 in primary APCs.
Tue Jan 15 00:00:00 EST 2013
The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lee SY,Goverman JM
14-0112 was used in Flow cytometry/Cell sorting to analyse the role of Tim-3 signalling within various innate immune cells on the development of experimental autoimmune encephalomyelitis.
Wed May 15 00:00:00 EDT 2013
FOXM1 promotes allergen-induced goblet cell metaplasia and pulmonary inflammation.
Molecular and cellular biology
Ren X,Shah TA,Ustiyan V,Zhang Y,Shinn J,Chen G,Whitsett JA,Kalin TV,Kalinichenko VV
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of transcriptional control of goblet cell differentiation and mucus hyperproduction, showing that FOXM1 promotes allergen-induced metaplasia and pulmonary inflammation.
Tue Jan 01 00:00:00 EST 2013
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes.
Developmental biology
Bai X,Trowbridge JJ,Riley E,Lee JA,DiBiase A,Kaartinen VM,Orkin SH,Zon LI
14-0112 was used in Flow cytometry/Cell sorting to study the role of TIF1γ in murine erythropoiesis and to assess its function in other blood lineages.
Tue Jan 15 00:00:00 EST 2013
Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration.
The Journal of comparative neurology
Lampron A,Pimentel-Coelho PM,Rivest S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.
PloS one
Obregón-Henao A,Henao-Tamayo M,Orme IM,Ordway DJ
14-0112 was used in Flow cytometry/Cell sorting to compare the bacterial burden, lung pathology and Gr1(int)CD11b(+) myeloid-derived suppressor cell immune responses in M. tuberculosis infected mice.
Fri Jun 20 00:00:00 EDT 2014
Intravital immunofluorescence for visualizing the microcirculatory and immune microenvironments in the mouse ear dermis.
PloS one
Kilarski WW,Güç E,Teo JC,Oliver SR,Lund AW,Swartz MA
14-0112-82 was used in Immunocytochemistry to develop an antibody-based method for intravital imaging of cell interactions of the living dermis while simultaneously assessing capillary permeability and lymphatic drainage function.
Fri Sep 27 00:00:00 EDT 2013
Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction.
PloS one
Duwaerts CC,Sun EP,Cheng CW,van Rooijen N,Gregory SH
14-0112 was used in Flow cytometry/Cell sorting to investigate whether iNKT and Kupffer cell suppression of neutrophil-dependent liver injury is interdependent, showing that cross-activation allows suppression of injury.
Fri Jul 11 00:00:00 EDT 2014
PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1.
Journal of neuroinflammation
Bodhankar S,Chen Y,Vandenbark AA,Murphy SJ,Offner H
14-0112 was used in Flow cytometry/Cell sorting to suggest that agents (for example antibodies) that can target and neutralise PD-L1/2 may have therapeutic potential for treatment of human stroke.
Mon Sep 09 00:00:00 EDT 2013
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.
The Journal of biological chemistry
McMahan RH,Wang XX,Cheng LL,Krisko T,Smith M,El Kasmi K,Pruzanski M,Adorini L,Golden-Mason L,Levi M,Rosen HR
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that FXR/TGR5 activation coordinates the immune phenotype of monocytes and macrophages.
Fri Apr 26 00:00:00 EDT 2013
Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.
The Journal of biological chemistry
Fernandez-Castaneda A,Arandjelovic S,Stiles TL,Schlobach RK,Mowen KA,Gonias SL,Gaultier A
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Feb 15 00:00:00 EST 2013
In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation.
PloS one
Vink PM,Smout WM,Driessen-Engels LJ,de Bruin AM,Delsing D,Krajnc-Franken MA,Jansen AJ,Rovers EF,van Puijenbroek AA,Kaptein A,Nolte MA,Garritsen A,van Eenennaam H
14-0112 was used in Flow cytometry/Cell sorting to study the function of TAK1 protein in the adult immune system.
Fri Sep 06 00:00:00 EDT 2013
Novel n-3 immunoresolvents: structures and actions.
Scientific reports
Dalli J,Colas RA,Serhan CN
14-0112 was used in Flow cytometry/Cell sorting to investigate the process of conversion of n-3 DPA to novel immunoresolvents for the resolution of inflammation.
Thu Oct 24 00:00:00 EDT 2013
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.
Immunity
Valdez PA,Vithayathil PJ,Janelsins BM,Shaffer AL,Williamson PR,Datta SK
14-0112 was used in Flow cytometry/Cell sorting to study the effect of prostaglandin E2 on the function of Th17 cells during differentiation.
Fri Apr 20 00:00:00 EDT 2012
Autophagy links inflammasomes to atherosclerotic progression.
Cell metabolism
Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Wed Apr 04 00:00:00 EDT 2012
Molecular definition of the identity and activation of natural killer cells.
Nature immunology
Bezman NA,Kim CC,Sun JC,Min-Oo G,Hendricks DW,Kamimura Y,Best JA,Goldrath AW,Lanier LL
14-0112 was used in Flow cytometry/Cell sorting to systematically define the transcriptome of mouse natural killer cells in several contexts.
Mon Oct 01 00:00:00 EDT 2012
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Oct 11 00:00:00 EDT 2012
Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a.
Blood
Berent-Maoz B,Montecino-Rodriguez E,Signer RA,Dorshkind K
14-0112 was used in Flow cytometry/Cell sorting to define a genetic basis for thymocyte progenitor aging.
Thu Jun 14 00:00:00 EDT 2012
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
The Journal of experimental medicine
Billiard F,Lobry C,Darrasse-Jèze G,Waite J,Liu X,Mouquet H,DaNave A,Tait M,Idoyaga J,Leboeuf M,Kyratsous CA,Burton J,Kalter J,Klinakis A,Zhang W,Thurston G,Merad M,Steinman RM,Murphy AJ,Yancopoulos GD,Aifantis I,Skokos D
14-0112 was used in Flow cytometry/Cell sorting to investigate how Dll4-Notch signaling affects pro-T cell fate and thymic DC development, showing that it is a novel Flt3-independent pathway for DC development and autoimmunity.
Mon May 07 00:00:00 EDT 2012
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
The Journal of experimental medicine
Boulard O,Kirchberger S,Royston DJ,Maloy KJ,Powrie FM
14-0112 was used in Flow cytometry/Cell sorting to investigate the genetic factors influencing the progression from Helicobacter hepaticus-driven colitis to tumorigenesis in a mouse model.
Mon Jul 02 00:00:00 EDT 2012
Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax.
Mucosal immunology
Rayamajhi M,Delgado C,Condon TV,Riches DW,Lenz LL
14-0112 was used in Flow cytometry/Cell sorting to investigate mechanisms of Bacillus anthracis spore traffic from the lungs to the lung-draining lymph nodes in a mouse model of inhalation anthrax.
Sun Jul 01 00:00:00 EDT 2012
Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.
PLoS pathogens
Castro-Seoane R,Hummerich H,Sweeting T,Tattum MH,Linehan JM,Fernandez de Marco M,Brandner S,Collinge J,Klöhn PC
14-0112 was used in Flow cytometry/Cell sorting to study the kinetics of prion accumulation in various splenic cell types at early stages of prion infection in mice.
Wed Feb 01 00:00:00 EST 2012
Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration.
Molecular medicine (Cambridge, Mass.)
De Paola M,Mariani A,Bigini P,Peviani M,Ferrara G,Molteni M,Gemma S,Veglianese P,Castellaneta V,Boldrin V,Rossetti C,Chiabrando C,Forloni G,Mennini T,Fanelli R
14-0112 was used in Immunocytochemistry to investigate the role of TLR4 in in vitro and in vivo settings of motor neuron degeneration.
Fri Sep 07 00:00:00 EDT 2012
ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment.
Journal of leukocyte biology
Long C,Hosseinkhani MR,Wang Y,Sriramarao P,Walcheck B
14-0112 was used in Flow cytometry/Cell sorting to study how impaired L-selectin shedding is a key mechanism underlying early neutrophil recruitment in conditional ADAM17 knockout mice during bacterial infection.
Sat Sep 01 00:00:00 EDT 2012
Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells.
Journal of leukocyte biology
Centuori SM,Trad M,LaCasse CJ,Alizadeh D,Larmonier CB,Hanke NT,Kartchner J,Janikashvili N,Bonnotte B,Larmonier N,Katsanis E
14-0112 was used in Immunohistochemistry to indicate that gr-MDSCs from TB hosts have the unanticipated ability to restrict immunosuppressive Tregs.
Thu Nov 01 00:00:00 EDT 2012
Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.
Journal of leukocyte biology
Movita D,Kreefft K,Biesta P,van Oudenaren A,Leenen PJ,Janssen HL,Boonstra A
14-0112 was used in Flow cytometry/Cell sorting to observe that freshly isolated Kupffer cells are endocytic and show a relatively high basal ROS content.
Mon Oct 01 00:00:00 EDT 2012
A TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950)
Ding X,Bian G,Leigh ND,Qiu J,McCarthy PL,Liu H,Aygun-Sunar S,Burdelya LG,Gudkov AV,Cao X
14-0112 was used in Flow cytometry/Cell sorting to investigate the effect of CBLB502 on graft-versus-tumour activity.
Thu Nov 15 00:00:00 EST 2012
Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950)
Boettcher S,Ziegler P,Schmid MA,Takizawa H,van Rooijen N,Kopf M,Heikenwalder M,Manz MG
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that TLR4-expressing nonhematopoietic cells are indispensable for LPS-induced, G-CSF-mediated myelopoietic responses.
Fri Jun 15 00:00:00 EDT 2012
The bone marrow functions as the central site of proliferation for long-lived NK cells.
Journal of immunology (Baltimore, Md. : 1950)
van Helden MJ,de Graaf N,Boog CJ,Topham DJ,Zaiss DM,Sijts AJ
14-0112 was used in Flow cytometry/Cell sorting to investigate the dynamics of natural killer cell responses after intranasal respiratory virus infection in mice.
Sat Sep 01 00:00:00 EDT 2012
Glucocorticoids relieve collectin-driven suppression of apoptotic cell uptake in murine alveolar macrophages through downregulation of SIRPα.
Journal of immunology (Baltimore, Md. : 1950)
McCubbrey AL,Sonstein J,Ames TM,Freeman CM,Curtis JL
14-0112 was used in Flow cytometry/Cell sorting to determine whether glucocorticoid treatment acts to increase apoptotic cell uptake by differentiated tissue macrophages.
Sun Jul 01 00:00:00 EDT 2012
The endothelial antigen ESAM monitors hematopoietic stem cell status between quiescence and self-renewal.
Journal of immunology (Baltimore, Md. : 1950)
Sudo T,Yokota T,Oritani K,Satoh Y,Sugiyama T,Ishida T,Shibayama H,Ezoe S,Fujita N,Tanaka H,Maeda T,Nagasawa T,Kanakura Y
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that the intensity of ESAM expression is useful to trace activated HSCs.
Sun Jul 01 00:00:00 EDT 2012
Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Nouri-Shirazi M,Guinet E
14-0112 was used in Flow cytometry/Cell sorting to investigate the causal relationship between nicotine-induced dendritic cell alterations and host response to vaccines.
Thu Mar 01 00:00:00 EST 2012
Semaphorin 7a links nerve regeneration and inflammation in the cornea.
Investigative ophthalmology & visual science
Namavari A,Chaudhary S,Ozturk O,Chang JH,Yco L,Sonawane S,Katam N,Khanolkar V,Hallak J,Sarkar J,Jain S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Mon Jul 09 00:00:00 EDT 2012
EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals.
American journal of physiology. Gastrointestinal and liver physiology
Tajima T,Murata T,Aritake K,Urade Y,Michishita M,Matsuoka T,Narumiya S,Ozaki H,Hori M
14-0112 was used in Flow cytometry/Cell sorting to investigate the possible role of PGE(2) in the LPS-inducible iNOS gene expression in murine distal ileal tissue and macrophages.
Thu Mar 01 00:00:00 EST 2012
A dynamic flux in natural killer cell subsets as a function of the duration of alcohol ingestion.
Alcoholism, clinical and experimental research
Ballas ZK,Cook RT,Shey MR,Coleman RA
14-0112 was used in Flow cytometry/Cell sorting to investigate the effect of duration of alcohol ingestion on NK cell function, showing a dynamic flux in NK cell subsets as a function of ingestion.
Tue May 01 00:00:00 EDT 2012
Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB.
Journal of neuroinflammation
Lin S,Liang Y,Zhang J,Bian C,Zhou H,Guo Q,Xiong Y,Li S,Su B
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Fri Feb 24 00:00:00 EST 2012
CCR2 defines a distinct population of NK cells and mediates their migration during influenza virus infection in mice.
PloS one
van Helden MJ,Zaiss DM,Sijts AJ
14-0112 was used in Flow cytometry/Cell sorting to determine the role of CCR2 in NK cell migration during intranasal influenza virus infection, showing that it defines a distinct population of NK cells and mediates their migration.
Mon Jun 10 00:00:00 EDT 2013
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Oncoimmunology
Mizutani T,Neugebauer N,Putz EM,Moritz N,Simma O,Zebedin-Brandl E,Gotthardt D,Warsch W,Eckelhart E,Kantner HP,Kalinke U,Lienenklaus S,Weiss S,Strobl B,Müller M,Sexl V,Stoiber D
14-0112 was used in Flow cytometry/Cell sorting to examine the role of Type 1 IFN signalling in the prevention of leukaemogenesis.
Mon Oct 01 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-0112 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
An intracameral injection of antigen induces in situ chemokines and cytokines required for the generation of circulating immunoregulatory monocytes.
PloS one
Pais R,Bhowmick S,Chattopadhyay S,Lemire Y,Sharafieh R,Yadav R,O'Rourke J,Cone RE
14-0112 was used in Flow cytometry/Cell sorting to further suggest that anterior chamber-associated immune deviation is initiated as the result of a mild proinflammatory response to intracameral injection.
Wed May 01 00:00:00 EDT 2013
Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease.
mBio
Orrskog S,Rounioja S,Spadafina T,Gallotta M,Norman M,Hentrich K,Fälker S,Ygberg-Eriksson S,Hasenberg M,Johansson B,Uotila LM,Gahmberg CG,Barocchi M,Gunzer M,Normark S,Henriques-Normark B
14-0112 was used in Blocking experiments to investigate the role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophages.
Wed Dec 26 00:00:00 EST 2012
Induction of histiocytic sarcoma in mouse skeletal muscle.
PloS one
Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Thu Feb 07 00:00:00 EST 2013
An early reduction in Treg cells correlates with enhanced local inflammation in cutaneous leishmaniasis in CCR6-deficient mice.
PloS one
Barth T,Schmidt D,Botteron C,Nguyen TT,Ritter U,Männel DN,Lechner A
14-0112 was used in Flow cytometry/Cell sorting to analyse T cell subsets in the lymph nodes of CCR6-deficient mice over the course of Leishmania major infection.
Wed Mar 06 00:00:00 EST 2013
CD94 is essential for NK cell-mediated resistance to a lethal viral disease.
Immunity
Fang M,Orr MT,Spee P,Egebjerg T,Lanier LL,Sigal LJ
14-0112 was used in Flow cytometry/Cell sorting to show that CD94, a molecule preferentially expressed by NK cells, is essential for the resistance of C57BL/6 mice to mousepox.
Fri Apr 22 00:00:00 EDT 2011
Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation.
Blood
Zlotoff DA,Zhang SL,De Obaldia ME,Hess PR,Todd SP,Logan TD,Bhandoola A
14-0112 was used in Flow cytometry/Cell sorting to explain why T cells are among the last of the hematopoietic lineages to recover after bone marrow transplantation (BMT).
Thu Aug 18 00:00:00 EDT 2011
Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking.
Blood
Mayol K,Biajoux V,Marvel J,Balabanian K,Walzer T
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of CXCR4 and S1P5 in natural killer cell trafficking.
Thu Nov 03 00:00:00 EDT 2011
Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage.
Blood
Hendricks DW,Fink PJ
14-0112 was used in Flow cytometry/Cell sorting to investigate the relationships between recent thymic emigrants and T-helper type 1 and 2 cells.
Thu Jan 27 00:00:00 EST 2011
Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice.
The Journal of clinical investigation
Cheung R,Shen F,Phillips JH,McGeachy MJ,Cua DJ,Heyworth PG,Pierce RH
14-0112 was used in Flow cytometry/Cell sorting to identify the MDL-1/Syk/PI3K/Akt/eNOS pathway as a potential new target for the prevention of the progression of SIRS to shock.
Tue Nov 01 00:00:00 EDT 2011
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells.
The Journal of experimental medicine
Hickman HD,Li L,Reynoso GV,Rubin EJ,Skon CN,Mays JW,Gibbs J,Schwartz O,Bennink JR,Yewdell JW
14-0112 was used in Flow cytometry/Cell sorting to demonstrate the ability of chemokines to assist antiviral CD8(+) T cells in distinguishing between antigen presenting cells.
Mon Nov 21 00:00:00 EST 2011
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells.
The Journal of experimental medicine
Hickman HD,Li L,Reynoso GV,Rubin EJ,Skon CN,Mays JW,Gibbs J,Schwartz O,Bennink JR,Yewdell JW
14-0112 was used in Flow cytometry/Cell sorting to demonstrate the ability of chemokines to assist antiviral CD8(+) T cells in distinguishing between antigen presenting cells.
Mon Nov 21 00:00:00 EST 2011
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses.
The Journal of experimental medicine
Wang L,Rubinstein R,Lines JL,Wasiuk A,Ahonen C,Guo Y,Lu LF,Gondek D,Wang Y,Fava RA,Fiser A,Almo S,Noelle RJ
14-0112 was used in Magnetic cell separation to show that VISTA has functional activities that are nonredundant with other Ig superfamily members and may play a role in the development of autoimmunity.
Mon Mar 14 00:00:00 EDT 2011
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America
Mahadevan NR,Rodvold J,Sepulveda H,Rossi S,Drew AF,Zanetti M
14-0112 was used in Flow cytometry/Cell sorting to suggest that tumour cells can control myeloid cells through transmissible ER stress, directing them toward a proinflammatory phenotype.
Tue Apr 19 00:00:00 EDT 2011
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.
Diabetes
Thayer TC,Delano M,Liu C,Chen J,Padgett LE,Tse HM,Annamali M,Piganelli JD,Moldawer LL,Mathews CE
14-0112 was used in Flow cytometry/Cell sorting to determine the cellular sources of ROS that are necessary for type 1 diabetes initiation, showing that superoxide production by macrophages and T cells is critical.
Mon Aug 01 00:00:00 EDT 2011
CD11b⁺, Ly6G⁺ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection.
PLoS pathogens
Fischer MA,Davies ML,Reider IE,Heipertz EL,Epler MR,Sei JJ,Ingersoll MA,Rooijen NV,Randolph GJ,Norbury CC
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that innate immune effector cells contain a peripheral poxvirus infection, preventing systemic spread of the virus.
Tue Nov 01 00:00:00 EDT 2011
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950)
Busche A,Schmitz S,Fleige H,Robbins SH,Walzer T,Stewart CA,Förster R,Messerle M,Prinz I
14-0112 was used in Flow cytometry/Cell sorting to determine that antiviral immune responses may induce sustained alterations in natural killer cell populations.
Tue Mar 01 00:00:00 EST 2011
A role for immature myeloid cells in immune senescence.
Journal of immunology (Baltimore, Md. : 1950)
Enioutina EY,Bareyan D,Daynes RA
14-0112 was used in Flow cytometry/Cell sorting to investigate the mechanisms responsible for the pathologic changes in age-associated increases in susceptibility to infectious and autoimmune diseases.
Sat Jan 15 00:00:00 EST 2011
Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing.
Journal of immunology (Baltimore, Md. : 1950)
Norling LV,Spite M,Yang R,Flower RJ,Perretti M,Serhan CN
14-0112 was used in Flow cytometry/Cell sorting to study the temporal generation and properties of endogenous microparticles produced in evolving self-limited inflammatory exudates in vivo.
Sun May 15 00:00:00 EDT 2011
Differential expression of NLRP3 among hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950)
Guarda G,Zenger M,Yazdi AS,Schroder K,Ferrero I,Menu P,Tardivel A,Mattmann C,Tschopp J
14-0112 was used in Flow cytometry/Cell sorting to characterize NOD-like receptor pyrin domain 3 (NLRP3) expression due to importance in health and disease.
Tue Feb 15 00:00:00 EST 2011
The role of CD14 in neutrophil recruitment within the liver microcirculation during endotoxemia.
Journal of immunology (Baltimore, Md. : 1950)
McAvoy EF,McDonald B,Parsons SA,Wong CH,Landmann R,Kubes P
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that liver microcirculation possesses a unique CD14-independent mechanism of LPS detection and activation of neutrophil recruitment.
Tue Feb 15 00:00:00 EST 2011
A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Human molecular genetics
McDonald DA,Shenkar R,Shi C,Stockton RA,Akers AL,Kucherlapati MH,Kucherlapati R,Brainer J,Ginsberg MH,Awad IA,Marchuk DA
14-0112 was used in Immunohistochemistry to attempt to improve the penetrance of a model of cerebral cavernous malformations.
Sat Jan 15 00:00:00 EST 2011
Generation of mature murine monocytes from heterogeneous bone marrow and description of their properties.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Francke A,Herold J,Weinert S,Strasser RH,Braun-Dullaeus RC
14-0112 was used in Functional assays to describe a novel approach to efficiently differentiate large numbers of mature inflammatory monocytes from heterogeneous bone marrow cell suspensions.
Thu Sep 01 00:00:00 EDT 2011
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.
PloS one
Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2011
Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.
PloS one
Pasieka TJ,Collins L,O'Connor MA,Chen Y,Parker ZM,Berwin BL,Piwnica-Worms DR,Leib DA
14-0112 was used in Flow cytometry/Cell sorting to examine HSV-1 pathogenesis in Stat1(-/-) mice and in IFNαβγR(-/-) mice, showing divergent viral pathogenesis between mouse strains.
Tue Feb 14 00:00:00 EST 2012
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Nature communications
Mkhikian H,Grigorian A,Li CF,Chen HL,Newton B,Zhou RW,Beeton C,Torossian S,Tatarian GG,Lee SU,Lau K,Walker E,Siminovitch KA,Chandy KG,Yu Z,Dennis JW,Demetriou M
14-0112 was used in Flow cytometry/Cell sorting to discover that genetic and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Tue Sep 20 00:00:00 EDT 2011
Lymphoid organ-resident dendritic cells exhibit unique transcriptional fingerprints based on subset and site.
PloS one
Elpek KG,Bellemare-Pelletier A,Malhotra D,Reynoso ED,Lukacs-Kornek V,DeKruyff RH,Turley SJ
14-0112 was used in Flow cytometry/Cell sorting to investigate whether local environments can influence the transcriptome of DC subsets, showing that lymphoid organ-resident dendritic cells exhibit unique transcriptomes based on site.
Fri Feb 24 00:00:00 EST 2012
Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.
PloS one
Grespi F,Ottina E,Yannoutsos N,Geley S,Villunger A
14-0112 was used in Flow cytometry/Cell sorting to evaluate the suitability of the lac-operon/lac-repressor (lacO/lacI) system for the regulation of the Vav-gene promoter, and the importance of IPTG.
Mon Mar 21 00:00:00 EDT 2011
FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia.
PloS one
Liesz A,Sun L,Zhou W,Schwarting S,Mracsko E,Zorn M,Bauer H,Sommer C,Veltkamp R
14-0112 was used in Flow cytometry/Cell sorting to detect a reduction of lymphocyte brain invasion by FTY720.
Fri Oct 14 00:00:00 EDT 2011
Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant.
Blood
Freire T,Zhang X,Dériaud E,Ganneau C,Vichier-Guerre S,Azria E,Launay O,Lo-Man R,Bay S,Leclerc C
14-0112 was used in Flow cytometry/Cell sorting to study dendritic cell antigen uptake and presentation by targeting the antigen receptor, macrophage galactose-type lectin (MGL), with tumor-associated Tn antigens.
Thu Nov 04 00:00:00 EDT 2010
Lymphotoxin-alpha contributes to lymphangiogenesis.
Blood
Mounzer RH,Svendsen OS,Baluk P,Bergman CM,Padera TP,Wiig H,Jain RK,McDonald DM,Ruddle NH
14-0112 was used in Immunohistochemistry-wholemount to investigate the role of Lymphotoxin-α in the function of lymphatic vessels.
Thu Sep 23 00:00:00 EDT 2010
Angiotensin II sustains brain inflammation in mice via TGF-beta.
The Journal of clinical investigation
Lanz TV,Ding Z,Ho PP,Luo J,Agrawal AN,Srinagesh H,Axtell R,Zhang H,Platten M,Wyss-Coray T,Steinman L
14-0112 was used in Flow cytometry/Cell sorting to identify angiotensin II as a paracrine mediator, sustaining inflammation in the CNS via TGF-β.
Sun Aug 01 00:00:00 EDT 2010
The adaptor molecule CARD9 is essential for tuberculosis control.
The Journal of experimental medicine
Dorhoi A,Desel C,Yeremeev V,Pradl L,Brinkmann V,Mollenkopf HJ,Hanke K,Gross O,Ruland J,Kaufmann SH
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of CARD9 in tuberculosis.
Mon Apr 12 00:00:00 EDT 2010
MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment.
The Journal of experimental medicine
Elliott JM,Wahle JA,Yokoyama WM
14-0112 was used in Flow cytometry/Cell sorting to investigate whether licensing is developmentally determined in the bone marrow, showing that MHC class I ligands are not absolutely required for licensing.
Mon Sep 27 00:00:00 EDT 2010
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells.
The Journal of experimental medicine
Henri S,Poulin LF,Tamoutounour S,Ardouin L,Guilliams M,de Bovis B,Devilard E,Viret C,Azukizawa H,Kissenpfennig A,Malissen B
14-0112 was used in Flow cytometry/Cell sorting to revisit the transfer of antigen that occurs between keratinocytes and the five distinguishable skin DC subsets and stress the high degree of functional specialization that exists among them.
Mon Jan 18 00:00:00 EST 2010
Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.
Brain : a journal of neurology
Vinukonda G,Csiszar A,Hu F,Dummula K,Pandey NK,Zia MT,Ferreri NR,Ungvari Z,LaGamma EF,Ballabh P
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
Notch dimerization is required for leukemogenesis and T-cell development.
Genes & development
Liu H,Chi AW,Arnett KL,Chiang MY,Xu L,Shestova O,Wang H,Li YM,Bhandoola A,Aster JC,Blacklow SC,Pear WS
14-0112 was used in Flow cytometry/Cell sorting to show that dimeric Notch transcriptional complexes are required for T-cell maturation and leukemic transformation but are dispensable for T-cell fate specification from a multipotential precursor.
Mon Nov 01 00:00:00 EDT 2010
Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150).
Journal of virology
Ferreira CS,Frenzke M,Leonard VH,Welstead GG,Richardson CD,Cattaneo R
14-0112 was used in Immunofluorescence to identify the cells that support primary measles infection before systemic spread.
Mon Mar 01 00:00:00 EST 2010
Angiopoietin-2-driven vascular remodeling in airway inflammation.
The American journal of pathology
Tabruyn SP,Colton K,Morisada T,Fuxe J,Wiegand SJ,Thurston G,Coyle AJ,Connor J,McDonald DM
14-0112 was used in Immunohistochemistry to determine the precise contribution of Ang2 to the transformation of capillaries into venules.
Wed Dec 01 00:00:00 EST 2010
Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function.
Journal of immunology (Baltimore, Md. : 1950)
Melillo JA,Song L,Bhagat G,Blazquez AB,Plumlee CR,Lee C,Berin C,Reizis B,Schindler C
14-0112 was used in Flow cytometry/Cell sorting to directly examine the role Stat3 plays in regulating dendritic cell activity.
Mon Mar 01 00:00:00 EST 2010
CD155 is involved in negative selection and is required to retain terminally maturing CD8 T cells in thymus.
Journal of immunology (Baltimore, Md. : 1950)
Qiu Q,Ravens I,Seth S,Rathinasamy A,Maier MK,Davalos-Misslitz A,Forster R,Bernhardt G
14-0112 was used in Magnetic cell separation to investigate the role of CD155 in negative selection of thymocytes.
Mon Feb 15 00:00:00 EST 2010
Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Chaves-Ferreira M,d'Orey F,Wencker M,Gonçalves-Sousa N,Decalf J,Simas JP,Hayday AC,Silva-Santos B
14-0112 was used in Flow cytometry/Cell sorting to investigate the properties of γδ T lymphocytes for adaptive and innate immunity.
Wed Dec 01 00:00:00 EST 2010
B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
International immunology
Smith SH,Haas KM,Poe JC,Yanaba K,Ward CD,Migone TS,Tedder TF
14-0112 was used in Flow cytometry/Cell sorting to support a model whereby B cells must integrate varied signals, including those from the BLyS- BR3 axis, CD22-ligand binding and antigen-receptor-mediated tonic signaling for their homeostatic maintenance in vivo.
Sun Aug 01 00:00:00 EDT 2010
Forkhead box M1 transcription factor is required for macrophage recruitment during liver repair.
Molecular and cellular biology
Ren X,Zhang Y,Snyder J,Cross ER,Shah TA,Kalin TV,Kalinichenko VV
14-0112 was used in Flow cytometry/Cell sorting to study how Foxm1 is critical for liver repair and is required for the recruitment of monocytes to the injured liver.
Mon Nov 01 00:00:00 EDT 2010
Induction of human blood group a antigen expression on mouse cells, using lentiviral gene transduction.
Human gene therapy
Fan X,Lang H,Zhou X,Zhang L,Yin R,Maciejko J,Giannitsos V,Motyka B,Medin JA,Platt JL,West LJ
14-0112 was used in Immunohistochemistry to determine the feasibility of developing a murine model of the ABO histo-blood group system.
Thu Jul 01 00:00:00 EDT 2010
Cryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation.
Infection and immunity
Guerrero A,Jain N,Wang X,Fries BC
14-0112 was used in Flow cytometry/Cell sorting to investigate the interaction between macrophages and cells from smooth-colony or mucoid-colony variants arising from phenotypic switching of Cryptococcus neoformans.
Mon Mar 01 00:00:00 EST 2010
A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis.
Arthritis and rheumatism
Wieten L,van der Zee R,Spiering R,Wagenaar-Hilbers J,van Kooten P,Broere F,van Eden W
14-0112 was used in Neutralization to study whether the boosting of endogenous heat-shock protein expression can restore effective immunoregulation through T cells specific for stress proteins.
Thu Apr 01 00:00:00 EDT 2010
Regulation of granulocyte and macrophage populations of murine bone marrow cells by G-CSF and CD137 protein.
PloS one
Jiang D,Schwarz H
14-0112 was used in Flow cytometry/Cell sorting to confirm the role of CD137 ligand signalling in regulating myelopoiesis, and demonstrate that this growth promoting influence is restricted to the monocytic lineage.
Mon Dec 13 00:00:00 EST 2010
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Cancer cell
Erler JT,Bennewith KL,Cox TR,Lang G,Bird D,Koong A,Le QT,Giaccia AJ
14-0112 was used in Immunofluorescence to demonstrate a critical role for LOX in premetastatic niche formation.
Tue Jan 06 00:00:00 EST 2009
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Cell stem cell
Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2009
Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury.
The Journal of clinical investigation
Heymann F,Meyer-Schwesinger C,Hamilton-Williams EE,Hammerich L,Panzer U,Kaden S,Quaggin SE,Floege J,Gröne HJ,Kurts C
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of several immune cell types within tubulointerstitial mononuclear cell infiltrates in the progression of kidney disease.
Fri May 01 00:00:00 EDT 2009
Oncogenic Kras initiates leukemia in hematopoietic stem cells.
PLoS biology
Sabnis AJ,Cheung LS,Dail M,Kang HC,Santaguida M,Hermiston ML,Passegué E,Shannon K,Braun BS
14-0112 was used in Flow cytometry/Cell sorting to conclude that MPD-initiating activity is restricted to the HSC compartment in Kras(G12D) mice.
Tue Mar 17 00:00:00 EDT 2009
The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection.
PLoS pathogens
Shimada K,Chen S,Dempsey PW,Sorrentino R,Alsabeh R,Slepenkin AV,Peterson E,Doherty TM,Underhill D,Crother TR,Arditi M
14-0112 was used in Flow cytometry/Cell sorting to investigate the role of the Nod/Rip2 pathway in responses to Chlamydophila pneumoniae infection, showing that it is essential for host defences against pneumonia.
Wed Apr 01 00:00:00 EDT 2009
Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.
Journal of cellular physiology
Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunofluorescence
Tue Sep 01 00:00:00 EDT 2009
Critical roles of lysosomal acid lipase in T cell development and function.
The American journal of pathology
Qu P,Du H,Wilkes DS,Yan C
14-0112-82 was used in Flow Cytometry to conclude that the altered development and function of lal(-/-) T cells contributes to disease formation in various organs during LAL deficiency.
Sun Mar 01 00:00:00 EST 2009
SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages.
The American journal of pathology
Kirby AC,Beattie L,Maroof A,van Rooijen N,Kaye PM
14-0112 was used in Flow cytometry/Cell sorting to show the protective activity of SIGNR1(+) marginal zone macrophages can be compensated for by activated red pulp macrophages.
Tue Sep 01 00:00:00 EDT 2009
alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation.
The American journal of pathology
Okazaki T,Ni A,Ayeni OA,Baluk P,Yao LC,Vossmeyer D,Zischinsky G,Zahn G,Knolle J,Christner C,McDonald DM
14-0112 was used in Immunohistochemistry-wholemount to investigate the role of integrin alpha5beta1 in remodelling blood and lymphatic vessels.
Mon Jun 01 00:00:00 EDT 2009
Inflammation recapitulates the ontogeny of lymphoid stromal cells.
Journal of immunology (Baltimore, Md. : 1950)
Peduto L,Dulauroy S,Lochner M,Späth GF,Morales MA,Cumano A,Eberl G
14-0112 was used in Functional assays to show that LS cells are both programmed during ontogeny and reinduced during inflammation.
Fri May 01 00:00:00 EDT 2009
Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950)
Graham KL,Zabel BA,Loghavi S,Zuniga LA,Ho PP,Sobel RA,Butcher EC
14-0112 was used in Flow cytometry/Cell sorting to investigate the involvement of chemokine-like receptor-1 in experimental autoimmune encephalomyelitis.
Sun Nov 15 00:00:00 EST 2009
Induction of distinct TLR2-mediated proinflammatory and proadhesive signaling pathways in response to Porphyromonas gingivalis fimbriae.
Journal of immunology (Baltimore, Md. : 1950)
Hajishengallis G,Wang M,Liang S
14-0112 was used in Blocking experiments to demonstrate that Porphyromonas gingivalis fimbriae activate two distinct TLR2 pathways mediating proinflammatory or proadhesive effects.
Mon Jun 01 00:00:00 EDT 2009
Chlamydial heat shock protein 60 induces acute pulmonary inflammation in mice via the Toll-like receptor 4- and MyD88-dependent pathway.
Infection and immunity
Bulut Y,Shimada K,Wong MH,Chen S,Gray P,Alsabeh R,Doherty TM,Crother TR,Arditi M
14-0112 was used in Flow cytometry/Cell sorting to suggest that cHSP60 causes lung inflammation and dendritic cell activation via Toll-like receptor 4 and MyD88.
Wed Jul 01 00:00:00 EDT 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
14-0112-82 was used in Flow Cytometry to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 EDT 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Immunohistochemistry
Wed Jan 07 00:00:00 EST 2009
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
PloS one
Chan AS,Jensen KK,Skokos D,Doty S,Lederman HK,Kaplan RN,Rafii S,Rivella S,Lyden D
14-0112 was used in Flow cytometry/Cell sorting to identify Id1 as crucial for the dynamic cross-talk between bone and bone marrow haematopoietic cells.
Tue Nov 24 00:00:00 EST 2009
Malarial hemozoin is a Nalp3 inflammasome activating danger signal.
PloS one
Dostert C,Guarda G,Romero JF,Menu P,Gross O,Tardivel A,Suva ML,Stehle JC,Kopf M,Stamenkovic I,Corradin G,Tschopp J
14-0112 was used in Flow cytometry/Cell sorting to hypothesized that hemozoin could activate the Nalp3 inflammasome.
Tue Aug 04 00:00:00 EDT 2009
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
14-0112-82 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
14-0112-82 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease.
The Journal of experimental medicine
Carlson T,Kroenke M,Rao P,Lane TE,Segal B
14-0112 was used in Flow cytometry/Cell sorting to demonstrate that ELR(+) CXC chemokines and CXCR2-expressing polymorphonuclear leukocytes are required for the development of experimental autoimmune encephalomyelitis.
Mon Apr 14 00:00:00 EDT 2008
CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury.
The American journal of pathology
Li G,Sanders JM,Bevard MH,Sun Z,Chumley JW,Galkina EV,Ley K,Sarembock IJ
14-0112 was used in Flow cytometry/Cell sorting to study the function of CD40 ligand in neointima formation following vascular injury in an atherogenic animal model.
Tue Apr 01 00:00:00 EDT 2008
Lipid raft-dependent uptake, signalling and intracellular fate of Porphyromonas gingivalis in mouse macrophages.
Cellular microbiology
Wang M,Hajishengallis G
14-0112 was used in Flow cytometry/Cell sorting to determine whether the oral pathogen Porphyromonas gingivalis enters macrophages via lipid rafts.
Wed Oct 01 00:00:00 EDT 2008
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.
The Journal of biological chemistry
Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D
Published figure using CD11b monoclonal antibody (Product # 14-0112-82) in Flow Cytometry
Fri Oct 24 00:00:00 EDT 2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
14-0112-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration.
The Journal of biological chemistry
Lee SU,Grigorian A,Pawling J,Chen IJ,Gao G,Mozaffar T,McKerlie C,Demetriou M
14-0112 was used in Flow cytometry/Cell sorting to identify hypomorphic Golgi processing as an inherited trait that determines susceptibility to EAE and provides a unique spontaneous model of MS.
Fri Nov 16 00:00:00 EST 2007
Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.
The Journal of experimental medicine
Bogunovic M,Ginhoux F,Wagers A,Loubeau M,Isola LM,Lubrano L,Najfeld V,Phelps RG,Grosskreutz C,Scigliano E,Frenette PS,Merad M
14-0112 was used in Flow cytometry/Cell sorting to explore dermal DC homeostasis in mice and humans both in the steady state and after haematopoietic cell transplantation.
Mon Nov 27 00:00:00 EST 2006
Porphyromonas gingivalis fimbriae proactively modulate beta2 integrin adhesive activity and promote binding to and internalization by macrophages.
Infection and immunity
Hajishengallis G,Wang M,Harokopakis E,Triantafilou M,Triantafilou K
14-0112 was used in Binding experiments to show that P. gingivalis fimbriae function as both an activator and a ligand of CD11b/CD18.
Sun Oct 01 00:00:00 EDT 2006
