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Caspase 9/p35/p10 Polyclonal Antibody

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Antibody Testing Data (14)

Caspase 9/p35/p10 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

Caspase 9/p35/p10 Antibody (10380-1-AP) in ICC/IF

Immunofluorescent analysis of ( ) fixed HepG2 cells using 10380-1-AP (Caspase 9/p35/p10 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IGG.

Caspase 9/p35/p10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Caspase 9/p35/p10 Antibody in Western Blot (WB)

Caspase 9/p35/p10 Antibody in Flow Cytometry (Flow)

Caspase 9/p35/p10 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10380-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 602 publications 602 publications

Immunohistochemistry (IHC)

View 29 publications 29 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 10 publications 10 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

ELISA (ELISA)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 8 publications 8 publications

Not applicable (N/A)

View 10 publications 10 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Hamster, Human, Mouse, Plant, Rat, Sheep

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Caspase 9/p35/p10 Fusion Protein Ag0404 (141-392 aa encoded by BC002452)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

10380-1-AP can recognize the pre- and cleaved- caspase 9.

Immunogen sequence: ALESLRGNA DLAYILSMEP CGHCLIINNV NFCRESGLRT RTGSNIDCEK LRRRFSSLHF MVEVKGDLTA KKMVLALLEL AQQDHGALDC CVVVILSHGC QASHLQFPGA VYGTDGCPVS VEKIVNIFNG TSCPSLGGKP KLFFIQACGG EQKDHGFEVA STSPEDESPG SNPEPDATPF QEGLRTFDQL DAISSLPTPS DIFVSYSTFP GFVSWRDPKS GSWYVETLDD IFEQWAHSED LQSLLLRVAN AVS (141-392 aa encoded by BC002452)

Target Information

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Chiral FA Conjugated CdTe/CdS Quantum Dots for Selective Cancer Ablation.

ACS nano

Li G,Zhang X,Fei X,Li J,Liu H,Liu W,Yang Y,Li B,Liu M,Yang G,Zhang T

Tue Aug 23 00:00:00 EDT 2022

Interference of KLF9 relieved the development of gestational diabetes mellitus by upregulating DDAH2.

Bioengineered

Chen W,Wang H,Liu J,Li K

Sat Jan 01 00:00:00 EST 2022

Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-A^Thr288-geminin dual signaling pathways.

Frontiers in pharmacology

Zhao H,Jia P,Nanding K,Wu M,Bai X,Morigen M,Fan L

Wed Jan 11 00:00:00 EST 2023

Tanshinone IIA Ameliorates Nonalcoholic Steatohepatitis in Mice by Modulating Neutrophil Extracellular Traps and Hepatocyte Apoptosis.

Evidence-based complementary and alternative medicine : eCAM

Xu L,Liu X,Jia T,Sun Y,Du Y,Wei S,Wang W,Zhang Y,Chen W,Zhang S

Tue Sep 13 00:00:00 EDT 2022

Single-cell profiling-guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma.

Clinical and translational medicine

Wang L,Wu Z,Xia Y,Lu X,Li J,Fan L,Qiao C,Qiu H,Gu D,Xu W,Li J,Jin H

Sun May 01 00:00:00 EDT 2022

Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.

European journal of pharmacology

Fan H,Cui J,Liu F,Zhang W,Yang H,He N,Dong Z,Dong J

Sat Oct 15 00:00:00 EDT 2022

PTX3 alleviates hard metal-induced acute lung injury through potentiating efferocytosis.

Ecotoxicology and environmental safety

Yan W,Ma D,Liu Y,Sun W,Cheng D,Li G,Zhou S,Wang Y,Wang H,Ni C

Sat Jan 15 00:00:00 EST 2022

Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice.

Neurotoxicity research

Li H,Sun S,Yin Z,Cao S,Ji X,Duan X,Gao H,Wang M,Fang Q,Dong W,Zhang X,Gu Y,Xue Q

Wed Jun 01 00:00:00 EDT 2022

Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Kan Y,Song M,Cui X,Yang Q,Zang Y,Li Q,Li Y,Cai W,Chen Y,Weng X,Wang Y,Zhu X

Tue Feb 01 00:00:00 EST 2022

Involvement of caspase in patulin-induced hepatotoxicity in vitro and in vivo.

Toxicon : official journal of the International Society on Toxinology

Zhang B,Huang C,Lu Q,Liang H,Li J,Xu D

Sun Jan 30 00:00:00 EST 2022

PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.

International journal of biological sciences

Chen YG,Liu HX,Hong Y,Dong PZ,Liu SY,Gao YR,Lu D,Li T,Wang DY,Wu DD,Ji XY

Tue Jul 12 00:00:00 EDT 2022

Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.

Frontiers in pharmacology

Han J,Zhang Z,Zhang Z,Yang S

Mon Mar 20 00:00:00 EDT 2023

Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.

Frontiers in immunology

Liu Y,Song X,Li C,Hu H,Li W,Wang L,Hu J,Liao C,Liang H,He Z,Ye L

Tue Apr 19 00:00:00 EDT 2022

Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.

Frontiers in pharmacology

Wang J,Wang K,Ding L,Zhao P,Zhang C,Wang H,Yang Z,Liu Z

Tue Aug 30 00:00:00 EDT 2022

N-linoleyltyrosine protects neurons against Aβ_1-40-induced cell toxicity via autophagy involving the CB₂/AMPK/mTOR/ULK1 pathway.

Brain research bulletin

Zhou Y,Li ZX,Liu YT,Xu ZC,Hu Y,Lv W,Yang ZY,Sheng YM,Liu S

Sat Oct 01 00:00:00 EDT 2022

TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.

Biology

Wang Y,Chen Y,Li C,Xiao Z,Yuan H,Zhang Y,Pang D,Tang X,Li M,Ouyang H

Fri Jan 14 00:00:00 EST 2022

Naringenin induces endoplasmic reticulum stress-mediated cell apoptosis and autophagy in human oral squamous cell carcinoma cells.

Journal of food biochemistry

Liu JF,Chang TM,Chen PH,Lin JS,Tsai YJ,Wu HM,Lee CJ

Tue Nov 01 00:00:00 EDT 2022

Enhancement of the cytotoxic effect of dihydroartemisinin in high-risk human papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway.

Photodiagnosis and photodynamic therapy

Che Q,Wang Q,Lu H,Li C,Zeng K

Thu Dec 01 00:00:00 EST 2022

Picropodophyllin Inhibits the Proliferation of Human Prostate Cancer DU145 and LNCaP Cells via ROS Production and PI3K/AKT Pathway Inhibition.

Biological & pharmaceutical bulletin

Zhu X,Chen X,Wang G,Lei D,Chen X,Lin K,Li M,Lin H,Li D,Zheng Q

Tue Aug 02 00:00:00 EDT 2022

Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation.

Frontiers in pharmacology

Xia B,Li Q,Wu J,Yuan X,Wang F,Lu X,Huang C,Zheng K,Yang R,Yin L,Liu K,You Q

Sat Jul 16 00:00:00 EDT 2022

Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.

PeerJ

Zhang L,Li C,Fu L,Yu Z,Xu G,Zhou J,Shen M,Feng Z,Zhu H,Xie T,Zhou L,Zhou X

Fri Jan 06 00:00:00 EST 2023

miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).

Journal of translational medicine

He Z,Cheng M,Hu J,Liu L,Liu P,Chen L,Cao D,Tang J

Sat Oct 01 00:00:00 EDT 2022

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

The Journal of biological chemistry

Zhou Y,Zheng R,Liu S,Disoma C,Du A,Li S,Chen Z,Dong Z,Zhang Y,Li S,Liu P,Razzaq A,Chen X,Liao Y,Tao S,Liu Y,Xu L,Zhang Q,Peng J,Deng X,Li S,Jiang T,Xia Z

Tue Feb 01 00:00:00 EST 2022

The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis.

Frontiers in cell and developmental biology

Wang J,Wu X,Sun X,Zhang L,Wang Q,Qu J,Wang Y,Li Y

Wed Feb 23 00:00:00 EST 2022

Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.

Reproductive toxicology (Elmsford, N.Y.)

Gu X,Liu H,Luo W,Wang X,Wang H,Li L

Thu Dec 01 00:00:00 EST 2022

Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.

Oxidative medicine and cellular longevity

Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z

Mon Apr 25 00:00:00 EDT 2022

Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Zhong Y,Luo R,Liu Q,Zhu J,Lei M,Liang X,Wang X,Peng X

Sat Jan 01 00:00:00 EST 2022

N⁶-adenomethylation of GsdmC is essential for Lgr5⁺ stem cell survival to maintain normal colonic epithelial morphogenesis.

Developmental cell

Du J,Sarkar R,Li Y,He L,Kang W,Liao W,Liu W,Nguyen T,Zhang L,Deng Z,Dougherty U,Kupfer SS,Chen M,Pekow J,Bissonnette M,He C,Li YC

Mon Aug 22 00:00:00 EDT 2022

HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.

Experimental cell research

Duan SF,Zhang MM,Zhang X,Liu W,Zhang SH,Yang B,Dong Q,Han JG,Yu HL,Li T,Ji XY,Wu DD,Zhang XJ

Tue Nov 01 00:00:00 EDT 2022

Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.

Asian journal of andrology

Tong Y,Guo YJ,Zhang Q,Bi HX,Kai K,Zhou RY

Tue Aug 30 00:00:00 EDT 2022

Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.

Frontiers in pharmacology

Cheng Z,Luo X,Zhu Z,Huang Y,Yan X

Sat Jul 16 00:00:00 EDT 2022

Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.

Frontiers in cell and developmental biology

Li W,Wang X,Liu T,Zhang Q,Cao J,Jiang Y,Sun Q,Li C,Wang W,Wang Y

Tue Mar 01 00:00:00 EST 2022

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells.

Medical oncology (Northwood, London, England)

Wang Y,Huang D,Song T,Qi X,Li M,Zhang H,Liu Y,Yang M

Wed Nov 09 00:00:00 EST 2022

Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway.

International journal of biological macromolecules

Liu Y,Li H,Zheng Z,Niu A,Liu S,Li W,Ren P,Liu Y,Inam M,Guan L,Ma H

Fri Jul 01 00:00:00 EDT 2022

FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.

Cells

Zhang Y,Yao E,Liu Y,Zhang Y,Ding M,Liu J,Chen X,Fan S

Tue Dec 13 00:00:00 EST 2022

Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.

Pharmacological research

Wei W,Li Y,Wang C,Gao S,Zhao Y,Yang Z,Wang H,Gao Z,Jiang Y,He Y,Zhao L,Gao H,Yao X,Hu Y

Mon Aug 01 00:00:00 EDT 2022

Proanthocyanidins inhibit the apoptosis and aging of nucleus pulposus cells through the PI3K/Akt pathway delaying intervertebral disc degeneration.

Connective tissue research

Chen HW,Liu MQ,Zhang GZ,Zhang CY,Wang ZH,Lin AX,Kang JH,Liu WZ,Guo XD,Wang YD,Kang XW

Tue Nov 01 00:00:00 EDT 2022

METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.

Cell death discovery

Yang L,Wu G,Wu Q,Peng L,Yuan L

Mon Feb 14 00:00:00 EST 2022

A natural halogenated fluoride adenosine analog 5'-fluorodeoxy adenosine induced anticolon cancer activity in vivo and in vitro.

Environmental toxicology

Ma L,Liu T,Lu Y,Dong Y,Zhao X,Man S

Sat Oct 01 00:00:00 EDT 2022

12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.

International journal of molecular sciences

Chen Q,Zheng Q,Yang Y,Luo Y,Wang H,Li H,Yang L,Hu C,Zhang J,Li Y,Xia H,Chen Z,Ma J,Tian X,Yang J

Fri Aug 12 00:00:00 EDT 2022

SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.

Scientific reports

Cai G,Ge Z,Xu Y,Cai L,Sun P,Huang G

Sat Jul 16 00:00:00 EDT 2022

Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.

European journal of pharmacology

Huang Y,Chen S,Pang L,Feng Z,Su H,Zhu W,Wei J

Tue Feb 15 00:00:00 EST 2022

Pinocembrin ameliorates lipopolysaccharide-induced HK-2 cell apoptosis and inflammation by regulating endoplasmic reticulum stress.

Experimental and therapeutic medicine

Zhang Y,Yu C,Feng Y

Mon Aug 01 00:00:00 EDT 2022

A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.

Journal of plastic surgery and hand surgery

Dong X,Zhang M,Chen Y,Li C,Wang Y,Jin X

Fri Apr 01 00:00:00 EDT 2022

A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.

Journal of plastic surgery and hand surgery

Dong X,Zhang M,Chen Y,Li C,Wang Y,Jin X

Fri Apr 01 00:00:00 EDT 2022

Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.

Cancers

Zhang Y,Xu T,Tian H,Wu J,Yu X,Zeng L,Liu F,Liu Q,Huang X

Thu Dec 15 00:00:00 EST 2022

A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.

Advanced healthcare materials

Zheng Z,Lei C,Liu H,Jiang M,Zhou Z,Zhao Y,Yu CY,Wei H

Sat Oct 01 00:00:00 EDT 2022

Inhibition of gap junction communication between cells can induce apoptosis of corpus cavernosum smooth muscle in guinea pigs.

Andrologia

Wang Y,Wang J,Hao Z,Yang H,Li Y,Tan M,Liu L,Feng S,Mei L,Qian B

Tue Feb 01 00:00:00 EST 2022

Nickel nanoparticles exert cytotoxic effects on trophoblast HTR-8/SVneo cells possibly via Nrf2/MAPK/caspase 3 pathway.

Environmental research

Li T,Li Z,Fu J,Tang C,Liu L,Xu J,Zhao J,Li Z

Thu Dec 01 00:00:00 EST 2022

Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.

Pharmaceutical biology

He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X

Thu Dec 01 00:00:00 EST 2022

Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.

Pharmaceutical biology

He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X

Thu Dec 01 00:00:00 EST 2022

Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.

Pharmaceutical biology

He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X

Thu Dec 01 00:00:00 EST 2022

Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.

Pharmaceutical biology

He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X

Thu Dec 01 00:00:00 EST 2022

Silica nanoparticles perturbed mitochondrial dynamics and induced myocardial apoptosis via PKA-DRP1-mitochondrial fission signaling.

The Science of the total environment

Zhao X,Xu H,Li Y,Liu Y,Li X,Zhou W,Wang J,Guo C,Sun Z,Li Y

Mon Oct 10 00:00:00 EDT 2022

Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells via modulating PI3K/AKT/EGFR and MAPK signaling pathways.

Frontiers in pharmacology

Lin S,Qin HZ,Li ZY,Zhu H,Long L,Xu LB

Wed Dec 21 00:00:00 EST 2022

Protective effect of low-dose radiation on doxorubicin-induced brain injury in mice.

Archives of biochemistry and biophysics

Gao Y,Dong J,Chen M,Wang T,Yang Z,He K,Li Y,Wang K,Jiang J,Zhang S

Sun Oct 30 00:00:00 EDT 2022

Cardiotoxicity of patulin was found in H9c2 cells.

Toxicon : official journal of the International Society on Toxinology

Zhang B,Liang H,Huang K,Li J,Xu D,Huang C,Li Y

Tue Feb 01 00:00:00 EST 2022

Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.

Cell death discovery

Han Z,Liu M,Xie Y,Zeng K,Zhan Z,Chen Y,Wang L,Chen X,Luo Y,Zeng Y,Zhan H,Lin Y,Zhang K,Zhu X,Liu S,Luo X,Zhou A

Fri Nov 04 00:00:00 EDT 2022

Inorganic arsenic promotes apoptosis of human immortal keratinocytes through the TGF-β1/ERK signaling pathway.

Environmental toxicology

Wu L,Yang F,Du S,Hu T,Wei S,Wang G,Zeng Q,Luo P

Wed Jun 01 00:00:00 EDT 2022

Protective role of selenium on MPP⁺ and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells.

Journal of receptor and signal transduction research

Yıldızhan K,Nazıroğlu M

Mon Aug 01 00:00:00 EDT 2022

HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.

Experimental & molecular medicine

Hu B,Wang P,Zhang S,Liu W,Lv X,Shi D,Zhao L,Liu H,Wang B,Chen S,Shao Z

Tue Mar 01 00:00:00 EST 2022

Dopamine 1 receptors inhibit apoptosis via activating CSE/H₂ S pathway in high glucose-induced vascular endothelial cells.

Cell biology international

Li H,Wu R,Xi Y,Li H,Chang G,Sun F,Wei C,Jiao L,Wen X,Zhang G,Zaid A,Hao J

Fri Jul 01 00:00:00 EDT 2022

Caspase-8 activation in neutrophils facilitates autoimmune kidney vasculitis through regulating CD4⁺ effector memory T cells.

Frontiers in immunology

Hu J,Huang Z,Yu M,Zhang P,Xia Z,Gao C

Fri Jan 06 00:00:00 EST 2023

Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.

Aging

Jiang XL,Tai H,Kuang JS,Zhang JY,Cui SC,Lu YX,Qi SB,Zhang SY,Li SM,Chen JP,Meng XS

Thu Oct 27 00:00:00 EDT 2022

Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.

Molecules (Basel, Switzerland)

Lee CW,Huang CC,Chi MC,Lee KH,Peng KT,Fang ML,Chiang YC,Liu JF

Fri Jan 07 00:00:00 EST 2022

The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.

Natural products and bioprospecting

Chen DK,Shao HY,Yang L,Hu JM

Thu Jan 27 00:00:00 EST 2022

Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.

Journal of molecular histology

Li J,Bu Y,Li B,Zhang H,Guo J,Hu J,Zhang Y

Mon Aug 01 00:00:00 EDT 2022

Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H⁺] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.

Toxicology and applied pharmacology

Zhang Y,Liang X,Guan J,Jin J,Zhang Y,Xu F,Fu J

Tue Mar 15 00:00:00 EDT 2022

An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.

Cell biology international

Zhou Z,Dong Y,Li N,Niu M,Wang S,Zhou Y,Sun Z,Chu P,Tang Z

Tue Nov 01 00:00:00 EDT 2022

MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats.

Brain research bulletin

Zhang F,Gou Z,Zhou Y,Huang L,Shao C,Wang M,Wu C,Lu L

Sat Oct 15 00:00:00 EDT 2022

Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.

Nutrients

Zhong Y,Li Z,Jin R,Yao Y,He S,Lei M,Wang X,Shi C,Gao L,Peng X

Thu Nov 24 00:00:00 EST 2022

Amentoflavone promotes ferroptosis by regulating reactive oxygen species (ROS) /5'AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) to inhibit the malignant progression of endometrial carcinoma cells.

Bioengineered

Sun Q,Zhen P,Li D,Liu X,Ding X,Liu H

Sun May 01 00:00:00 EDT 2022

Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.

Journal of cellular and molecular medicine

Zhou Y,Liu Y,Xu G,Liu L,Li H,Li Y,Yin J,Wang X,Yu Z

Mon Aug 01 00:00:00 EDT 2022

Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.

Frontiers in endocrinology

Jiang XL,Tai H,Xiao XS,Zhang SY,Cui SC,Qi SB,Hu DD,Zhang LN,Kuang JS,Meng XS,Li SM

Tue Dec 06 00:00:00 EST 2022

Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury.

Pharmaceutics

Zhang R,Chen M,Deng Z,Kong L,Shen B,Zhang L

Fri Dec 23 00:00:00 EST 2022

AMBRA1 promotes dsRNA- and virus-induced apoptosis through interacting with and stabilizing MAVS.

Journal of cell science

Lin Y,Huang C,Gao H,Li X,Lin Q,Zhou S,Huo Z,Huang Y,Liu C,Zhang P

Sat Jan 01 00:00:00 EST 2022

miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1.

Environmental toxicology

Xin X,Duan L,Yang H,Yu H,Bao Y,Jia D,Wu N,Qiao Y

Fri Apr 01 00:00:00 EDT 2022

Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.

Cell death & disease

Lv Q,Han X,Ni J,Ma Q,Dai R,Liu J,Liu J,Zhai Y,Shen Q,Sun L,Liu H,Rao J,Xu H

Thu Oct 13 00:00:00 EDT 2022

Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.

Medical oncology (Northwood, London, England)

Sun Y,Guan X,Zhang T,Li Y,Shi H,Chitakunye AT,Hong H,Zhang S,Zhu Q,Cai L

Tue Aug 16 00:00:00 EDT 2022

Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.

International journal of molecular sciences

Benedetti R,Arena A,Romeo MA,Gilardini Montani MS,Gonnella R,Santarelli R,Trivedi P,Cirone M

Sun Aug 14 00:00:00 EDT 2022

MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang Z,Deng K,Kang Z,Wang F,Fan Y

Fri Jul 01 00:00:00 EDT 2022

A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.

Journal of cellular and molecular medicine

Tai H,Tong YJ,Yu R,Yu Y,Yao SC,Li LB,Liu Y,Cui XZ,Kuang JS,Meng XS,Jiang XL

Wed Jun 01 00:00:00 EDT 2022

Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.

European journal of medicinal chemistry

Liang JJ,Yu WL,Yang L,Xie BH,Qin KM,Yin YP,Yan JJ,Gong S,Liu TY,Zhou HB,Hong K

Sat Feb 05 00:00:00 EST 2022

Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.

Chemico-biological interactions

Zhong Y,Sun D,Yao Y,Liu Q,Guo T,Wang X,Peng X

Tue Mar 01 00:00:00 EST 2022

Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.

Chinese medicine

Pan B,Xia Y,Gao Z,Zhao G,Wang L,Fang S,Liu L,Yan S

Wed Mar 09 00:00:00 EST 2022

Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Xu Y,Wang X,Han D,Wang J,Luo Z,Jin T,Shi C,Zhou X,Lin L,Shan J

Wed Jul 20 00:00:00 EDT 2022

LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.

In vitro cellular & developmental biology. Animal

Kong X,Fei Q,Pan C,Jin J,Zheng J,Wu D,Li H,Huang X

Fri Apr 01 00:00:00 EDT 2022

Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.

Cancer letters

Yan R,Dai W,Wu R,Huang H,Shu M

Sat May 28 00:00:00 EDT 2022

The involvement of TRPM2 on the MPP⁺-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.

Neurological research

Yildizhan K,Çinar R,Naziroğlu M

Fri Jul 01 00:00:00 EDT 2022

Thyroid stimulating hormone aggravates diabetic retinopathy through the mitochondrial apoptotic pathway.

Journal of cellular physiology

Lin D,Qin R,Guo L

Sat Jan 01 00:00:00 EST 2022

DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H₂ S pathway in diabetic mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Wen X,Xi Y,Zhang Y,Jiao L,Shi S,Bai S,Sun F,Chang G,Wu R,Hao J,Li H

Sat Jan 01 00:00:00 EST 2022

Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis.

Computational and mathematical methods in medicine

Feng Q,Wang D,Guo P,Zhang Z,Feng J

Tue Oct 25 00:00:00 EDT 2022

Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis.

Computational and mathematical methods in medicine

Feng Q,Wang D,Guo P,Zhang Z,Feng J

Tue Oct 25 00:00:00 EDT 2022

Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis.

Computational and mathematical methods in medicine

Feng Q,Wang D,Guo P,Zhang Z,Feng J

Tue Oct 25 00:00:00 EDT 2022

Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis.

Computational and mathematical methods in medicine

Feng Q,Wang D,Guo P,Zhang Z,Feng J

Tue Oct 25 00:00:00 EDT 2022

Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.

International journal of pharmaceutics

Jia D,Wang F,Lu Y,Hu P,Wang R,Li G,Liu R,Li J,Liu H,Fan Q,Yuan F

Wed May 25 00:00:00 EDT 2022

Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3.

American journal of translational research

Ma T,Li H,Yang W,Liu Q,Yan H

Mon Mar 14 00:00:00 EDT 2022

MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.

BMC musculoskeletal disorders

Xu P,Chang J,Ma G,Liao F,Xu T,Wu Y,Yin Z

Sat Nov 26 00:00:00 EST 2022

Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.

Folia histochemica et cytobiologica

Xiong W,Huang XL,Li CY,Wang XL,Lan HW,Wang TT,Chen ZL,Yang QP,Hu AL,Xia YF,Zhu FR,Zhou ZZ

Mon Jan 02 00:00:00 EST 2023

Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER Stress.

Microbiology spectrum

Liu Z,Fu Y,Huang Y,Zeng F,Rao J,Xiao X,Sun X,Jin H,Li J,Yang J,Du W,Liu L

Wed Dec 21 00:00:00 EST 2022

The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.

Free radical biology & medicine

Ai J,Wang H,Chu P,Shopit A,Niu M,Ahmad N,Tesfaldet T,Wang FH,Fang JN,Li X,Tang SJ,Han QJ,Han G,Peng J,Tang Z

Tue Feb 01 00:00:00 EST 2022

1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.

Toxicology and applied pharmacology

Chang X,Wang J,Bian J,Liu Z,Guo M,Li Z,Wu Y,Zhai X,Zuo D

Thu Sep 01 00:00:00 EDT 2022

Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.

Journal of oncology

Wang S,Tan J,Chen L,Wang J

Sat Jul 16 00:00:00 EDT 2022

Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats.

Oxidative medicine and cellular longevity

Zhang Y,Wang L,Weng Y,Wang D,Wang R,Wang H,Wang L,Shen S,Wang H,Li Y,Wang Y

Wed Sep 07 00:00:00 EDT 2022

Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats.

Oxidative medicine and cellular longevity

Zhang Y,Wang L,Weng Y,Wang D,Wang R,Wang H,Wang L,Shen S,Wang H,Li Y,Wang Y

Wed Sep 07 00:00:00 EDT 2022

Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.

Chemico-biological interactions

Zheng H,Liu Q,Wang S,Liu X,Ma M,Shen T,Wang X,Ren D

Sat Oct 01 00:00:00 EDT 2022

Astragaloside IV Inhibits the Proliferation of Human Uterine Leiomyomas by Targeting IDO1.

Cancers

Qiu T,Li D,Liu Y,Ren H,Yang X,Luo W

Mon Sep 12 00:00:00 EDT 2022

Astragaloside IV Inhibits the Proliferation of Human Uterine Leiomyomas by Targeting IDO1.

Cancers

Qiu T,Li D,Liu Y,Ren H,Yang X,Luo W

Mon Sep 12 00:00:00 EDT 2022

Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway.

Redox report : communications in free radical research

Cui Y,Li F,Zhu X,Xu J,Muhammad A,Chen Y,Li D,Liu B,Wang C,Wang Z,Ma S,Liu X,Shi Y

Thu Dec 01 00:00:00 EST 2022

Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.

Virulence

Jie W,Rui-Fen Z,Zhong-Xiang H,Yan W,Wei-Na L,Yong-Ping M,Jing S,Jing-Yi C,Wan-Hong L,Xiao-Hua H,Zhi L,Yan S

Thu Dec 01 00:00:00 EST 2022

Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.

Bioengineered

Zhao J,Pan B,Zhou X,Wu C,Hao F,Zhang J,Liu L

Tue Feb 01 00:00:00 EST 2022

Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.

BioMed research international

Liu G,Guan Y,Liu Y,Wang Y,Zhang J,Liu Y,Liu X

Tue Dec 06 00:00:00 EST 2022

Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.

Food & function

Zhong Y,Liu J,Sun D,Guo T,Yao Y,Xia X,Shi C,Peng X

Mon Mar 21 00:00:00 EDT 2022

Glaucocalyxin A impairs tumor growth via amplification of the ATF4/CHOP/CHAC1 cascade in human oral squamous cell carcinoma.

Journal of ethnopharmacology

Wang X,He MJ,Chen XJ,Bai YT,Zhou G

Mon May 23 00:00:00 EDT 2022

Lactobacillus rhamnosus Ameliorates Multi-Drug-Resistant Bacillus cereus-Induced Cell Damage through Inhibition of NLRP3 Inflammasomes and Apoptosis in Bovine Endometritis.

Microorganisms

Liu N,Wang X,Shan Q,Xu L,Li Y,Chu B,Yang L,Wang J,Zhu Y

Mon Jan 10 00:00:00 EST 2022

Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.

Oxidative medicine and cellular longevity

Li B,Lu ZY,Jiang SD,Jiang LS,Zheng XF

Fri Jul 08 00:00:00 EDT 2022

N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K / AKT pathway.

Cell cycle (Georgetown, Tex.)

Kang J,Wang Y,Guo X,He X,Liu W,Chen H,Wang Z,Lin A,Kang X

Tue Nov 01 00:00:00 EDT 2022

Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.

Photodermatology, photoimmunology & photomedicine

Wang J,Wang Q,Chen P,Li Q,Li Z,Xu M,Zeng K,Li C

Fri Jul 01 00:00:00 EDT 2022

Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Varier KM,Dan G,Liu W,Wu G,Xiao C,Lei H,Ling T,Jiang Y,Chen Y,Ben-David Y,Li Y,Zhang N,Gajendran B,Shen X

Thu Dec 01 00:00:00 EST 2022

Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.

Cancers

Zhang L,Jin GZ,Li D

Mon Nov 21 00:00:00 EST 2022

Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.

Cancers

Zhang L,Jin GZ,Li D

Mon Nov 21 00:00:00 EST 2022

Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.

Life sciences

Chen Y,Liu H,Zheng Q,Li H,You H,Feng Y,Feng W

Sat Oct 01 00:00:00 EDT 2022

Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.

Experimental and therapeutic medicine

Wang N,Zhu P,Huang R,Sun L,Dong D,Gao Y

Mon Nov 01 00:00:00 EDT 2021

Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.

FEBS open bio

Tian L,Wang S,Zhao L,Lu X,Zhu C,Gong H,Yang W

Sun Aug 01 00:00:00 EDT 2021

Downregulated MicroRNA-327 Attenuates Oxidative Stress-Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway.

Frontiers in pharmacology

Zheng T,Yang J,Zhang J,Yang C,Fan Z,Li Q,Zhai Y,Liu H,Yang J

Wed May 26 00:00:00 EDT 2021

Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.

PPAR research

Zhang J,Cheng P,Dai W,Ji J,Wu L,Feng J,Wu J,Yu Q,Li J,Guo C

Sat Feb 20 00:00:00 EST 2021

Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.

Journal of cellular physiology

Mou J,Xu J,Wang Z,Wang C,Yang X,Wang X,Xue H,Wu M,Xu L

Mon Mar 01 00:00:00 EST 2021

Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.

Frontiers in immunology

Chu BX,Li YN,Liu N,Yuan LX,Chen SY,Zhu YH,Wang JF

Mon Feb 14 00:00:00 EST 2022

The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.

Journal of cellular and molecular medicine

Liu J,Liu L,Han YS,Yi J,Guo C,Zhao HQ,Ling J,Wang YH

Sun Aug 01 00:00:00 EDT 2021

Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.

BMC complementary medicine and therapies

Tai H,Jiang XL,Lan ZM,Li Y,Kong L,Yao SC,Song N,Lv MJ,Wu J,Yang P,Xiao XS,Yang GL,Kuang JS,Jia LQ

Mon Mar 22 00:00:00 EDT 2021

Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.

Phytotherapy research : PTR

Luo C,Sun H,Peng J,Gao C,Bao L,Ji R,Zhang C,Zhu W,Jin Y

Mon Feb 01 00:00:00 EST 2021

Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.

Gastroenterologia y hepatologia

Zhou G,Qin M,Zhang X,Yang J,Yu H

Fri Jan 01 00:00:00 EST 2021

Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.

Oncology letters

Wang P,Wang C,Liu C

Fri Jan 01 00:00:00 EST 2021

Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.

Journal of hazardous materials

Xiaoli F,Yaqing Z,Ruhui L,Xuan L,Aijie C,Yanli Z,Chen H,Lili C,Longquan S

Sun Aug 15 00:00:00 EDT 2021

Pseudoginsengenin DQ exerts antitumour activity against hypopharyngeal cancer cells by targeting the HIF-1α-GLUT1 pathway.

Cancer cell international

Wang S,Cai Y,Feng Q,Gao J,Teng B

Mon Jul 19 00:00:00 EDT 2021

Abnormal Glu/mGluR_2/3/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.

Neural regeneration research

Liu J,Han YS,Liu L,Tang L,Yang H,Meng P,Zhao HQ,Wang YH

Thu Apr 01 00:00:00 EDT 2021

Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.

Oncology reports

Feng X,Cao A,Qin T,Zhang Q,Fan S,Wang B,Song B,Yu X,Li L

Mon Nov 01 00:00:00 EDT 2021

Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.

Translational psychiatry

Wang L,Zhang Y,Chen L,Wang J,Jia F,Li F,Froehlich TE,Hou Y,Hao Y,Shi Y,Deng H,Zhang J,Huang L,Xie X,Fang S,Xu L,Xu Q,Guan H,Wang W,Shen J,Qian Y,Wang X,Shan L,Tan C,Yu Y,Wang X,Chen F,Zhang L,Li X,Shi X,Ke X,Li T

Thu Jun 03 00:00:00 EDT 2021

Lenvatinib Induces AKT/NF-κB Inactivation, Apoptosis Signal Transduction and Growth Inhibition of Non-small Cell Lung Cancer In Vivo.

Anticancer research

Liu YC,Hsu FT,Chung JG,Weng MC,Ting CY,Tsai CJ,Lan A,Wu JY,Lin CC,Lin SS

Tue Jun 01 00:00:00 EDT 2021

Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.

PeerJ

Lei X,Chen G,Li J,Wen W,Gong J,Fu J

Wed Apr 27 00:00:00 EDT 2022

Stiffness of the extracellular matrix affects apoptosis of nucleus pulposus cells by regulating the cytoskeleton and activating the TRPV2 channel protein.

Cellular signalling

Yu ZH,Ji YC,Li K,Liang T,Liu B,Chen HL,Ni L,Luo ZP,Yang HL

Sun Aug 01 00:00:00 EDT 2021

Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.

Journal of experimental & clinical cancer research : CR

Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C

Tue Aug 24 00:00:00 EDT 2021

A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.

Food science & nutrition

Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F

Thu Jul 01 00:00:00 EDT 2021

Cordyceps acid alleviates lung cancer in nude mice.

Journal of biochemical and molecular toxicology

Wang J,Chen H,Li W,Shan L

Mon Mar 01 00:00:00 EST 2021

JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.

Cancer biology & medicine

Zhang Z,Ye C,Liu J,Xu W,Wu C,Yu Q,Xu X,Zeng X,Jin H,Wu Y,Yan H

Tue Sep 28 00:00:00 EDT 2021

Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.

Nutrition and cancer

Hu Z,Wang H,Fu Y,Ma K,Ma X,Wang J

Wed Sep 08 00:00:00 EDT 2021

Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.

International journal of molecular medicine

Zhu F,Li X,Tang X,Jiang J,Han Y,Li Y,Ma C,Liu Z,He Y

Thu Jul 01 00:00:00 EDT 2021

miR-21-5p inhibits inflammation injuries in LPS-treated H9c2 cells by regulating PDCD4.

American journal of translational research

Xue J,Liu J,Xu B,Yu J,Zhang A,Qin L,Liu C,Yang Y

Thu Nov 18 00:00:00 EST 2021

Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.

Human & experimental toxicology

Chen Y,Tian Y,Jin G,Cui Z,Guo W,Zhang X,Liu X

Wed Dec 01 00:00:00 EST 2021

Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.

PPAR research

Cheng Z,Guo C

Tue Mar 30 00:00:00 EDT 2021

NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.

Cancer cell international

Liu S,Zhang Y,Cui S,Song D,Li B,Chen Q,Yao G,Gong B

Sat Nov 13 00:00:00 EST 2021

UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.

Cancer letters

Wang D,He J,Dong J,Wu S,Liu S,Zhu H,Xu T

Thu Oct 28 00:00:00 EDT 2021

Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.

Frontiers in cell and developmental biology

Cao W,Li Y,Sun H,Yang C,Zhu J,Xie C,Li X,Wu J,Geng S,Wang L,Sun L,Geng G,Han H,Zhong C

Fri Aug 06 00:00:00 EDT 2021

Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Wang ZD,Feng Y,Sun L,Gan J,Li X,Ding WF,Chen XM

Thu Apr 01 00:00:00 EDT 2021

SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.

Frontiers in oncology

Wen D,Liu WL,Lu ZW,Cao YM,Ji QH,Wei WJ

Sun May 23 00:00:00 EDT 2021

Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats.

Frontiers in pharmacology

Zhang KK,Wang H,Qu D,Chen LJ,Wang LB,Li JH,Liu JL,Xu LL,Yoshida JS,Xu JT,Xie XL,Li DR

Wed Mar 10 00:00:00 EST 2021

Curcuma oil ameliorates benign prostatic hyperplasia through suppression of the nuclear factor-kappa B signaling pathway in rats.

Journal of ethnopharmacology

Wang S,Li Y,Li W,Zhang K,Yuan Z,Cai Y,Xu K,Zhou J,Du Z

Thu Oct 28 00:00:00 EDT 2021

Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment.

Journal of dairy science

Gao HN,Ren FZ,Wen PC,Xie LX,Wang R,Yang ZN,Li YX

Mon Feb 01 00:00:00 EST 2021

Prolonged exposure to the herbicide atrazine suppresses immune cell functions by inducing spleen cell apoptosis in rats.

Ecotoxicology and environmental safety

Ge J,Liu J,Wang T,Huang D,Li J,Zhang S,Wang M,Liu W,Zhao L

Wed Sep 01 00:00:00 EDT 2021

AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang Z,Wu H,Huang S,Chen L,Chen X,Zhang W,Liao L,Zhang X

Tue Jun 01 00:00:00 EDT 2021

Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.

Biochemical pharmacology

Jhou AJ,Chang HC,Hung CC,Lin HC,Lee YC,Liu WT,Han KF,Lai YW,Lin MY,Lee CH

Mon Feb 01 00:00:00 EST 2021

Protective effect of Huyang Yangkun Formula on ovarian function in premature ovarian insufficiency rats based on apoptotic mechanism.

Journal of ethnopharmacology

Wang L,Li M,Liu J,Nie G,Li Y,Yang H

Mon Nov 15 00:00:00 EST 2021

Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.

Metallomics : integrated biometal science

Li M,Cheng W,Zhang L

Fri Nov 19 00:00:00 EST 2021

Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.

Journal of immunology research

Song M,Li ZH,Gu HS,Tang RY,Zhang R,Zhu YL,Liu JL,Zhang JJ,Wang LY

Thu Nov 11 00:00:00 EST 2021

MicroRNA-222 Transferred From Semen Extracellular Vesicles Inhibits Sperm Apoptosis by Targeting BCL2L11.

Frontiers in cell and developmental biology

Ding Y,Ding N,Zhang Y,Xie S,Huang M,Ding X,Dong W,Zhang Q,Jiang L

Fri Nov 26 00:00:00 EST 2021

MicroRNA-1 affects the development of the neural crest and craniofacial skeleton via the mitochondrial apoptosis pathway.

Experimental and therapeutic medicine

Zhao N,Qin W,Wang D,Raquel AG,Yuan L,Mao Y,Ma C,Xiao Z,Ma J

Thu Apr 01 00:00:00 EDT 2021

Resistance of bone marrow mesenchymal stem cells in a stressed environment - Comparison with osteocyte cells.

International journal of medical sciences

Shimasaki M,Ueda S,Ichiseki T,Hirata H,Kawahara N,Ueda Y

Mon Oct 18 00:00:00 EDT 2021

ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.

International journal of biological sciences

Zhang H,Xia P,Liu J,Chen Z,Ma W,Yuan Y

Mon Dec 20 00:00:00 EST 2021

Integrating Network Pharmacology and Experimental Verification to Explore the Mechanism of Effect of Zuojin Pills in Pancreatic Cancer Treatment.

Drug design, development and therapy

Wang K,Miao X,Kong F,Huang S,Mo J,Jin C,Zheng Y

Thu Jan 20 00:00:00 EST 2022

MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA.

International journal of molecular sciences

Yang YL,Tsai MC,Chang YH,Wang CC,Chu PY,Lin HY,Huang YH

Tue Jun 01 00:00:00 EDT 2021

Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.

Journal of gastroenterology and hepatology

Yang LY,Cheng ZJ,Liu Z,Wang D,Zhang N,Fan ZL,Cai HQ,Zhang Y,Cai Y,Xu X,Wang JH,Du GH,Hao JJ,Wang MR

Wed Sep 01 00:00:00 EDT 2021

LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.

Cell death & disease

Tao Y,Zhang J,Chen L,Liu X,Yao M,Zhang H

Tue May 18 00:00:00 EDT 2021

Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.

Chemico-biological interactions

Li C,Shi L,Peng C,Yu G,Zhang Y,Du Z

Mon Mar 01 00:00:00 EST 2021

LncRNA TMPO-AS1 serves as a sponge for miR-4731-5p modulating breast cancer progression through FOXM1.

American journal of translational research

Wang Y,Ma J,Li R,Gao X,Wang H,Jiang G

Thu Nov 18 00:00:00 EST 2021

Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of Alzheimer's disease.

Journal of receptor and signal transduction research

Övey İS,Nazıroğlu M

Tue Jun 01 00:00:00 EDT 2021

Timolol induces necroptosis, apoptosis and senescence concentration-dependently in rabbit Limbal stem cells in vitro.

Life sciences

Jiang GJ,Li BB,Fan TJ

Thu Jul 15 00:00:00 EDT 2021

miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.

Biochemical pharmacology

Han S,Wang Z,Liu J,Wang HD,Yuan Q

Tue Jun 01 00:00:00 EDT 2021

Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.

International immunopharmacology

Wang F,Younis M,Luo Y,Zhang L,Yuan L

Tue Jun 01 00:00:00 EDT 2021

A novel amphibian-derived peptide alleviated ultraviolet B-induced photodamage in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang X,Feng C,Wang S,Wang Y,Fu Z,Zhang Y,Sun H,Xie C,Fu Y,Tao J,Luo M,Yang X

Thu Apr 01 00:00:00 EDT 2021

Role of PKA/CREB/BDNF signaling in PM2.5-induced neurodevelopmental damage to the hippocampal neurons of rats.

Ecotoxicology and environmental safety

Liu J,Liu B,Yuan P,Cheng L,Sun H,Gui J,Pan Y,Huang D,Chen H,Jiang L

Sat May 01 00:00:00 EDT 2021

Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.

Frontiers in oncology

Cheng Y,Wang G,Zhao L,Dai S,Han J,Hu X,Zhou C,Wang F,Ma H,Li B,Meng Z

Wed Dec 15 00:00:00 EST 2021

Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.

Frontiers in chemistry

Shang Y,Wang Q,Li J,Liu H,Zhao Q,Huang X,Dong H,Chen W,Gui R,Nie X

Sat Apr 03 00:00:00 EDT 2021

Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca²⁺ homeostasis.

Cell biology and toxicology

Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Peng X

Fri Oct 01 00:00:00 EDT 2021

Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.

Gene

Jin P,Li LH,Shi Y,Hu NB

Sat Jan 30 00:00:00 EST 2021

FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury.

Redox biology

Cai Y,Yang E,Yao X,Zhang X,Wang Q,Wang Y,Liu J,Fan W,Yi K,Kang C,Wu J

Fri Jan 01 00:00:00 EST 2021

The inhibition of colorectal cancer growth by the natural product macrocarpal I.

Free radical biology & medicine

Qi L,Zhang Y,Zhang W,Wang Y,Han Y,Ding Y

Fri Jan 01 00:00:00 EST 2021

Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression.

Stem cell research & therapy

Yao C,Zhou Y,Wang H,Deng F,Chen Y,Zhu X,Kong Y,Pan L,Xue L,Zhou X,Shi C,Sheng X

Mon Aug 09 00:00:00 EDT 2021

Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.

Food research international (Ottawa, Ont.)

Han B,Jiang P,Jiang L,Li X,Ye X

Mon Mar 01 00:00:00 EST 2021

PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway.

Cell death & disease

Han Z,Liu D,Chen L,He Y,Tian X,Qi L,Chen L,Luo Y,Chen Z,Hu X,Li G,Zhan L,Wang Y,Li Q,Chen P,Liu Z,Guo H

Fri May 28 00:00:00 EDT 2021

RTN1-C mediates cerebral ischemia/reperfusion injury via modulating autophagy.

Acta biochimica et biophysica Sinica

Ling J,Cai H,Lin M,Qi S,Du J,Chen L

Thu Feb 04 00:00:00 EST 2021

MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.

Journal of physiology and biochemistry

Jiao Y,Zhao D,Gao F,Hu X,Hu X,Li M,Cui Y,Wei X,Xie C,Zhao Y,Gao Y

Mon Feb 01 00:00:00 EST 2021

Tea Polyphenols Prevent Sepsis-Induced Lung Injury via Promoting Translocation of DJ-1 to Mitochondria.

Frontiers in cell and developmental biology

Jia CM,Zhang FW,Wang SJ,Wang W,Li Y

Sat Apr 23 00:00:00 EDT 2022

Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.

Food & function

Liu XL,Zhao YC,Zhu HY,Wu M,Zheng YN,Yang M,Cheng ZQ,Ding CB,Liu WC

Mon Nov 29 00:00:00 EST 2021

Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.

Frontiers in nutrition

Li X,Gao M,Zhu S,Yin L,Zhang B,Qi Y,Zhao Y,Yu Y,Xu L

Tue Jun 15 00:00:00 EDT 2021

Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.

Journal of pharmacological sciences

Xianjun F,Xirui X,Jie T,Huiwen M,Shaojun Z,Qiaoyun L,Yunxin L,Xuqun S

Sun Aug 01 00:00:00 EDT 2021

Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.

Journal of ethnopharmacology

Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F

Tue Aug 10 00:00:00 EDT 2021

Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.

Frontiers in veterinary science

Ou G,Jiang X,Gao A,Li X,Lin Z,Pei S

Wed Feb 23 00:00:00 EST 2022

A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.

Frontiers in pharmacology

Wang T,Dong J,Yuan X,Wen H,Wu L,Liu J,Sui H,Deng W

Sun May 02 00:00:00 EDT 2021

Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.

Frontiers in pharmacology

Li C,Sui C,Wang W,Yan J,Deng N,Du X,Cheng F,Ma X,Wang X,Wang Q

Fri Jul 09 00:00:00 EDT 2021

Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.

Frontiers in pharmacology

Yang M,Li WY,Xie J,Wang ZL,Wen YL,Zhao CC,Tao L,Li LF,Tian Y,Sheng J

Sat May 08 00:00:00 EDT 2021

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway.

PPAR research

Wu L,Yu Q,Cheng P,Guo C

Mon Apr 25 00:00:00 EDT 2022

The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.

Free radical biology & medicine

Ai J,Wang H,Chu P,Shopit A,Niu M,Ahmad N,Tesfaldet T,Wang FH,Fang JN,Li X,Tang SJ,Han G,Peng J,Tang Z

Fri Jan 01 00:00:00 EST 2021

H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.

Technology and health care : official journal of the European Society for Engineering and Medicine

Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J

Wed Aug 18 00:00:00 EDT 2021

Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.

Archives of pharmacal research

Wang J,Su Q,Wu Q,Chen K,Ullah A,Ghauri MA,Zhang Y

Mon Nov 01 00:00:00 EDT 2021

siRNAs Targeting Mouse-Specific lncRNA AA388235 Induce Human Tumor Cell Pyroptosis/Apoptosis.

Frontiers in oncology

Chen YR,Feng WY,Cheng YX,Zhu H,Liu HJ,Gao Y,Zhou WJ

Fri Jul 02 00:00:00 EDT 2021

Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.

Journal of ethnopharmacology

Li L,Wang J,Feng L,Fan J,Wang J,Tan N,Wang Z

Wed Sep 15 00:00:00 EDT 2021

A newly identified small molecular compound acts as a protein kinase inhibitor to suppress metastasis of colorectal cancer.

Bioorganic chemistry

Qi L,Zhang Y,Song F,Han Y,Ding Y

Mon Feb 01 00:00:00 EST 2021

Activation of HSP70 impedes tert-butyl hydroperoxide (t-BHP)-induced apoptosis and senescence of human nucleus pulposus stem cells via inhibiting the JNK/c-Jun pathway.

Molecular and cellular biochemistry

Zhang S,Liu W,Wang P,Hu B,Lv X,Chen S,Wang B,Shao Z

Sat May 01 00:00:00 EDT 2021

LncRNA SNHG16 contributes to tumor progression via the miR-302b-3p/SLC2A4 axis in pancreatic adenocarcinoma.

Cancer cell international

Xu H,Miao X,Li X,Chen H,Zhang B,Zhou W

Tue Jan 12 00:00:00 EST 2021

Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca²⁺ Homeostasis, and Bcl2 Expression.

Molecular nutrition & food research

Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Zhang Y,Peng X

Sun Aug 01 00:00:00 EDT 2021

Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.

Journal of cellular biochemistry

Zheng Y,Nie P,Xu S

Mon Jun 01 00:00:00 EDT 2020

Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.

Acta biochimica et biophysica Sinica

Li Y,Liu M,Yi J,Song X,Zheng X,Liu D,Wang S,Chu C,Yang J

Tue Dec 29 00:00:00 EST 2020

FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy.

Cancer letters

Lin JZ,Wang WW,Hu TT,Zhu GY,Li LN,Zhang CY,Xu Z,Yu HB,Wu HF,Zhu JG

Tue Jan 28 00:00:00 EST 2020

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway.

International journal of molecular sciences

Yuan J,Zhang G,Li X,Ma Q,Cheng W,Wang W,Zhang B,Hu T,Song G

Wed Nov 25 00:00:00 EST 2020

AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.

Cancer management and research

Xu F,Xu Y,Xiong JH,Zhang JH,Wu J,Luo J,Xiong JP

Wed Apr 13 00:00:00 EDT 2022

Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.

European journal of medicinal chemistry

Yu M,Zeng M,Pan Z,Wu F,Guo L,He G

Sun Mar 01 00:00:00 EST 2020

Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.

Ecotoxicology and environmental safety

Guan S,Tao S,Huang Y,Jin Y,Hu Y,Lu J

Tue Dec 01 00:00:00 EST 2020

Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.

Frontiers in pharmacology

Su W,Zhao J,Fan TJ

Mon Sep 28 00:00:00 EDT 2020

Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.

Endocrine pathology

Gucer H,Caliskan S,Kefeli M,Mete O

Sun Mar 01 00:00:00 EST 2020

A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.

Frontiers in pharmacology

Pan B,Wang Y,Wu C,Jia J,Huang C,Fang S,Liu L

Sat Jan 30 00:00:00 EST 2021

Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Hu X,Xia M,Wang J,Yu H,Chai J,Zhang Z,Sun Y,Su J,Sun L

Tue Sep 01 00:00:00 EDT 2020

MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.

Chemico-biological interactions

Du J,Li J,Gao M,Guan Q,Liu T,Wu Y,Li Z,Zuo D,Zhang W,Wu Y

Mon May 25 00:00:00 EDT 2020

The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.

Frontiers in pharmacology

Yan Z,Zhan J,Qi W,Lin J,Huang Y,Xue X,Pan X

Mon Sep 28 00:00:00 EDT 2020

Exogenous H₂S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.

Aging and disease

Sun Y,Lu F,Yu X,Wang B,Chen J,Lu F,Peng S,Sun X,Yu M,Chen H,Wang Y,Zhang L,Liu N,Du H,Zhao D,Zhang W

Wed Apr 01 00:00:00 EDT 2020

An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.

Chemico-biological interactions

He S,Li A,Zhang W,Zhang L,Liu Y,Li K,Qin X

Wed Jul 01 00:00:00 EDT 2020

Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway.

Journal of Cancer

Yu J,Wang W,Yao W,Yang Z,Gao P,Liu M,Wang H,Chen S,Wang D,Wang W,Sun G

Mon Sep 28 00:00:00 EDT 2020

Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.

Bioscience, biotechnology, and biochemistry

Zhang L,Wang Z,Kong D,Zhao X,Chen X,Chai W

Sat Aug 01 00:00:00 EDT 2020

Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis.

International journal of molecular sciences

Bronowicka-Adamska P,Bentke A,Lasota M,Wróbel M

Thu Feb 06 00:00:00 EST 2020

MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4.

Nutrition, metabolism, and cardiovascular diseases : NMCD

Zhang X,Wang Z,Li W,Huang R,Zheng D,Bi G

Mon Mar 09 00:00:00 EDT 2020

Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zheng Y,Nie P,Xu S

Wed Jan 01 00:00:00 EST 2020

Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.

Toxicology and applied pharmacology

Ma Z,Lu Y,Yang F,Li S,He X,Gao Y,Zhang G,Ren E,Wang Y,Kang X

Sun Apr 19 00:00:00 EDT 2020

Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.

Biochemistry and cell biology = Biochimie et biologie cellulaire

Liu A,Zuo Z,Liu L,Liu L

Thu Oct 01 00:00:00 EDT 2020

Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.

International journal of molecular medicine

Zhu X,Feng J,Fu W,Shu X,Wan X,Liu J

Mon Jun 01 00:00:00 EDT 2020

MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.

The Kaohsiung journal of medical sciences

Yang QY,Yang KP,Li ZZ

Wed Jan 01 00:00:00 EST 2020

Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion.

Cancer management and research

Jing X,Chen Y,Chen Y,Shi G,Lv S,Cheng N,Feng C,Xin Z,Zhang L,Wu J

Wed Apr 13 00:00:00 EDT 2022

Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.

Technology in cancer research & treatment

Ma J,Qi J,Li S,Zhang C,Wang H,Shao L,Yuan X,Sha Q

Mon Jan 04 00:00:00 EST 2021

The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.

International journal of clinical and experimental pathology

Zhang X,Chen Y,Wang K,Tang J,Chen Y,Jin G,Liu X

Tue Oct 13 00:00:00 EDT 2020

Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.

Biochemical pharmacology

Liu X,Zhang Y,Wu S,Xu M,Shen Y,Yu M,Fan J,Wei S,Xu C,Huang L,Zhao H,Li X,Ye X

Fri May 01 00:00:00 EDT 2020

Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Wang Y,Chen Y,Zhang H,Chen J,Cao J,Chen Q,Li X,Sun C

Tue Dec 01 00:00:00 EST 2020

Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.

Journal of Cancer

Yang B,Bai H,Sa Y,Zhu P,Liu P

Mon Sep 28 00:00:00 EDT 2020

Paris saponin II-induced paraptosis-associated cell death increased the sensitivity of cisplatin.

Toxicology and applied pharmacology

Man S,Lv P,Cui J,Liu F,Peng L,Ma L,Liu C,Gao W

Sun Nov 01 00:00:00 EDT 2020

Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.

Chinese medicine

Lin HY,Han HW,Wang YS,He DL,Sun WX,Feng L,Wen ZL,Yang MK,Lu GH,Wang XM,Qi JL,Yang YH

Wed Apr 13 00:00:00 EDT 2022

BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu J,Shangguan Y,Sun J,Cong W,Xie Y

Tue Sep 01 00:00:00 EDT 2020

miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation.

Frontiers in genetics

Wang J,Qu J,Li Y,Feng Y,Ma J,Zhang L,Chu C,Hu H,Wang Y,Ji D

Mon Dec 07 00:00:00 EST 2020

The roles of SHANK1 in the development of colon cancer.

Cell biochemistry and function

Wang L,Lv Y,Liu G

Wed Jul 01 00:00:00 EDT 2020

ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.

Toxicology letters

Gao Z,Dlamini MB,Ge H,Jiang L,Geng C,Li Q,Shi X,Liu Y,Cao J

Thu Oct 01 00:00:00 EDT 2020

Protective effects of alfalfa saponins on oxidative stress-induced apoptotic cells.

Food & function

Cui Y,Liu B,Sun X,Li Z,Chen Y,Guo Z,Liu H,Li D,Wang C,Zhu X,Shi Y

Wed Sep 23 00:00:00 EDT 2020

1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.

Biochemical pharmacology

Zhou Y,Fu X,Guan Y,Gong M,He K,Huang B

Sat Feb 01 00:00:00 EST 2020

Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Ma Z,Yang J,Yang Y,Wang X,Chen G,Shi A,Lu Y,Jia S,Kang X,Lu L

Sun Mar 01 00:00:00 EST 2020

Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.

Planta medica

Zeng Q,Zeng Y,Nie X,Guo Y,Zhan Y

Tue Dec 01 00:00:00 EST 2020

NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.

Journal of Cancer

Ren Y,Wang Y,Hao S,Yang Y,Xiong W,Qiu L,Tao J,Tang A

Sat Oct 31 00:00:00 EDT 2020

The In Vivo Radiosensitizing Effect of Magnolol on Tumor Growth of Hepatocellular Carcinoma.

In vivo (Athens, Greece)

Chen YS,Sun R,Chen WL,Yau YC,Hsu FT,Chung JG,Tsai CJ,Hsieh CL,Chiu YM,Chen JH

Fri Jun 18 00:00:00 EDT 2021

PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.

Journal of cellular and molecular medicine

Dong P,Fu H,Chen L,Zhang S,Zhang X,Li H,Wu D,Ji X

Wed Jul 01 00:00:00 EDT 2020

Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.

Toxicology in vitro : an international journal published in association with BIBRA

Su Q,Wang J,Liu F,Zhang Y

Sat Aug 01 00:00:00 EDT 2020

Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell.

Journal of food biochemistry

Peng F,Li G,Xie Y,Yin HY,Li XJ,Yang YD

Mon Jun 01 00:00:00 EDT 2020

Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.

Scientific reports

Xin X,Li Y,Liu H

Tue Nov 10 00:00:00 EST 2020

Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.

Scientific reports

Xin X,Li Y,Liu H

Tue Nov 10 00:00:00 EST 2020

Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Man S,Yang L,Xiang H,Lu G,Wang Y,Liu C,Gao W

Fri May 01 00:00:00 EDT 2020

Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.

Theranostics

Ren L,Feng W,Shao J,Ma J,Xu M,Zhu BZ,Zheng N,Liu S

Wed Apr 28 00:00:00 EDT 2021

Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.

Experimental and therapeutic medicine

Wang X,Zhou J,Yang J,Wang S,Yang L

Sun Nov 01 00:00:00 EDT 2020

Protective effect of astaxanthin against SnS₂ nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Yuan L,Liang P,Qu Y,An T,Wang J,Deng X,Bai L,Shen P,Bai D

Sun Nov 01 00:00:00 EDT 2020

Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.

Toxicology in vitro : an international journal published in association with BIBRA

Yang T,Fan TJ,Xu B

Sat Aug 01 00:00:00 EDT 2020

Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.

Life sciences

Liu J,Deng X,Sun X,Dong J,Huang J

Tue Sep 15 00:00:00 EDT 2020

Glycyrrhizic Acid Modulates Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits Protein Kinase B- and Extracellular Signal-Regulated Kinase-Mediated Metastatic Potential in Hepatocellular Carcinoma In Vitro and In Vivo.

The American journal of Chinese medicine

Tsai JJ,Pan PJ,Hsu FT,Chung JG,Chiang IT

Fri Sep 04 00:00:00 EDT 2020

Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats.

Evidence-based complementary and alternative medicine : eCAM

Li S,Dong J,Ta G,Liu Y,Cui J,Li X,Song J,Liu A,Cheng G

Wed Apr 13 00:00:00 EDT 2022

The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.

Chemical & pharmaceutical bulletin

Feng B,Zhao C,Li J,Yu J,Zhang Y,Zhang X,Tian T,Zhao L

Fri Apr 30 00:00:00 EDT 2021

HAX1 enhances the survival and metastasis of non-small cell lung cancer through the AKT/mTOR and MDM2/p53 signaling pathway.

Thoracic cancer

Liang Z,Zhong Y,Meng L,Chen Y,Liu Y,Wu A,Li X,Wang M

Sun Nov 01 00:00:00 EDT 2020

Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.

Molecular medicine reports

Wang X,Lin Y,Zheng Y

Tue Sep 01 00:00:00 EDT 2020

Latcripin-7A, derivative of Lentinula edodes C_91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G₁ phase in breast cancer cells.

Applied microbiology and biotechnology

Din SRU,Zhong M,Nisar MA,Saleem MZ,Hussain A,Khinsar KH,Alam S,Ayub G,Kanwal S,Li X,Zhang W,Wang X,Ning A,Cao J,Huang M

Tue Dec 01 00:00:00 EST 2020

Nei Endonuclease VIII-Like1 (NEIL1) Inhibits Apoptosis of Human Colorectal Cancer Cells.

BioMed research international

Xue W,Liu Y,Xin N,Miao J,Du J,Wang Y,Shi H,Wei Y,Zhang H,Chen Y,Gao Y,Li D,Feng Y,Yan J,Zhang J,Hou N,Huang C,Han J

Fri Apr 16 00:00:00 EDT 2021

C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.

Frontiers in cell and developmental biology

Li J,Yang Q,Han L,Pan C,Lei C,Chen H,Lan X

Tue Oct 13 00:00:00 EDT 2020

Dihydroartemisinin Modulates Apoptosis and Autophagy in Multiple Myeloma through the P38/MAPK and Wnt/β-Catenin Signaling Pathways.

Oxidative medicine and cellular longevity

Wu X,Liu Y,Zhang E,Chen J,Huang X,Yan H,Cao W,Qu J,Gu H,Xu R,He J,Cai Z

Wed May 12 00:00:00 EDT 2021

Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.

Cell death & disease

Fan J,Ren D,Wang J,Liu X,Zhang H,Wu M,Yang G

Tue Feb 18 00:00:00 EST 2020

Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.

Oxidative medicine and cellular longevity

Cui G,Li L,Xu W,Wang M,Jiao D,Yao B,Xu K,Chen Y,Yang S,Long M,Li P,Guo Y

Tue Nov 10 00:00:00 EST 2020

Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.

Oxidative medicine and cellular longevity

Li C,Wang X,Yan J,Cheng F,Ma X,Chen C,Wang W,Wang Q

Thu May 13 00:00:00 EDT 2021

Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.

BMC complementary medicine and therapies

Dai GH,Chen X,Ren ZM,Dai CJ,Tong YL,Chai KQ

Thu Sep 03 00:00:00 EDT 2020

Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway.

Frontiers in pharmacology

Wu D,Zhong P,Wang Y,Zhang Q,Li J,Liu Z,Ji A,Li Y

Tue Jan 05 00:00:00 EST 2021

Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer.

BioMed research international

Kang D,Zuo W,Wu Q,Zhu Q,Liu P

Thu Apr 29 00:00:00 EDT 2021

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.

FEBS open bio

Zheng B,Shi C,Muhammed FK,He J,Abdullah AO,Liu Y

Sun Nov 01 00:00:00 EDT 2020

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.

FEBS open bio

Zheng B,Shi C,Muhammed FK,He J,Abdullah AO,Liu Y

Sun Nov 01 00:00:00 EDT 2020

Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.

Toxicology in vitro : an international journal published in association with BIBRA

Kang N,Cao S,Jiang B,Zhang Q,Donkor PO,Zhu Y,Qiu F,Gao X

Tue Sep 01 00:00:00 EDT 2020

PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Feng AL,Han X,Meng X,Chen Z,Li Q,Shu W,Dai H,Zhu J,Yang Z

Thu Oct 01 00:00:00 EDT 2020

Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.

International journal of biological sciences

Deng X,Liu J,Liu L,Sun X,Huang J,Dong J

Mon Sep 27 00:00:00 EDT 2021

A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer.

Journal of cellular and molecular medicine

Zhang P,Cao M,Zhang Y,Xu L,Meng F,Wu X,Xia T,Chen Q,Shi G,Wu P,Chen L,Lu Z,Yin J,Cai B,Cao S,Miao Y,Jiang K

Tue Sep 01 00:00:00 EDT 2020

Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.

European journal of pharmacology

Jiang L,Wen C,He Q,Sun Y,Wang J,Lan X,Rohondia S,Dou QP,Shi X,Liu J

Fri Jun 05 00:00:00 EDT 2020

Hexapeptide derived from prothymosin alpha attenuates cisplatin-induced acute kidney injury.

Clinical and experimental nephrology

Torigoe K,Obata Y,Torigoe M,Oka S,Yamamoto K,Koji T,Ueda H,Mukae H,Nishino T

Fri May 01 00:00:00 EDT 2020

Synergistic Utilization of Necrostatin-1 and Z-VAD-FMK Efficiently Promotes the Survival of Compression-Induced Nucleus Pulposus Cells via Alleviating Mitochondrial Dysfunction.

BioMed research international

Chen S,Tian Q,Shang C,Yang L,Wei N,Shang G,Ji Y,Kou H,Lu S,Liu H

Tue Jun 08 00:00:00 EDT 2021

Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.

Molecular therapy : the journal of the American Society of Gene Therapy

Zhong B,Liu M,Bai C,Ruan Y,Wang Y,Qiu L,Hong Y,Wang X,Li L,Li B

Wed Apr 08 00:00:00 EDT 2020

ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.

Aging

Long P,He M,Yan W,Chen W,Wei D,Wang S,Zhang Z,Ge W,Chen T

Sat Dec 19 00:00:00 EST 2020

The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.

OncoTargets and therapy

Shang Y,Wang Q,Li J,Zhao Q,Huang X,Dong H,Liu H,Zhang Y,Zhang J,Gui R,Nie X

Tue Apr 12 00:00:00 EDT 2022

Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p.

Pathology, research and practice

Dao R,Wudu M,Hui L,Jiang J,Xu Y,Ren H,Qiu X

Sun Mar 01 00:00:00 EST 2020

Therapeutic Efficacy and Inhibitory Mechanism of Regorafenib Combined With Radiation in Colorectal Cancer.

In vivo (Athens, Greece)

Liu YC,Chiang IT,Chung JG,Hsieh JH,Chiang CH,Weng MC,Hsu FT,Lee YH,Chang CS,Lin SS

Fri Jun 18 00:00:00 EDT 2021

A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb.

International journal of molecular sciences

Zhang B,Zhang T,Zhang TY,Wang N,He S,Wu B,Jin HX

Sat Jul 18 00:00:00 EDT 2020

Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.

Journal of medicinal chemistry

Shi X,Zhang T,Lou H,Song H,Li C,Fan P

Thu Oct 22 00:00:00 EDT 2020

Matrine and baicalin inhibit apoptosis induced by Panton-Valentine leukocidin of Staphylococcus aureus in bovine mammary epithelial cells.

Journal of dairy science

Jia F,Ma W,Zhang X,Wang D,Zhou X

Sun Mar 01 00:00:00 EST 2020

Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis.

Acta pharmaceutica Sinica. B

Zhang X,Zhang P,An L,Sun N,Peng L,Tang W,Ma D,Chen J

Sat Aug 01 00:00:00 EDT 2020

Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.

Cell cycle (Georgetown, Tex.)

Song Q,He Z,Li B,Liu J,Liu L,Liao W,Xiong Y,Song C,Yang S,Liu Y

Thu Oct 01 00:00:00 EDT 2020

Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.

Life sciences

Wang B,Xu H,Hu X,Ma W,Zhang J,Li Y,Yu M,Zhang Y,Li X,Ye X

Sun Mar 15 00:00:00 EDT 2020

Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.

Oxidative medicine and cellular longevity

Almoiliqy M,Wen J,Qaed E,Sun Y,Lian M,Mousa H,Al-Azab M,Zaky MY,Chen D,Wang L,Al-Sharabi A,Liu Z,Sun P,Lin Y

Thu Sep 02 00:00:00 EDT 2021

Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.

Life sciences

Shopit A,Niu M,Wang H,Tang Z,Li X,Tesfaldet T,Ai J,Ahmad N,Al-Azab M,Tang Z

Sat Feb 01 00:00:00 EST 2020

Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.

Oncology reports

An K,Zhang Y,Liu Y,Yan S,Hou Z,Cao M,Liu G,Dong C,Gao J,Liu G

Tue Sep 01 00:00:00 EDT 2020

Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.

The Journal of investigative dermatology

Yu X,Li H,Zhu M,Hu P,Liu X,Qing Y,Wang X,Wang H,Wang Z,Xu J,Tan R,Guo Q,Hui H

Thu Oct 01 00:00:00 EDT 2020

Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.

Pharmacological research

Zheng L,Han X,Hu Y,Zhao X,Yin L,Xu L,Qi Y,Xu Y,Han X,Liu K,Peng J

Tue Jan 01 00:00:00 EST 2019

Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.

Pharmacological research

Zheng L,Han X,Hu Y,Zhao X,Yin L,Xu L,Qi Y,Xu Y,Han X,Liu K,Peng J

Tue Jan 01 00:00:00 EST 2019

The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.

Free radical biology & medicine

Li Z,Li Q,Lv W,Jiang L,Geng C,Yao X,Shi X,Liu Y,Cao J

Tue Jan 01 00:00:00 EST 2019

The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.

Free radical biology & medicine

Li Z,Li Q,Lv W,Jiang L,Geng C,Yao X,Shi X,Liu Y,Cao J

Tue Jan 01 00:00:00 EST 2019

TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Wu X,Kong Q,Zhan L,Qiu Z,Huang Q,Song X

Fri Nov 01 00:00:00 EDT 2019

Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.

Journal of cellular physiology

Li Y,Zheng Q,Sun D,Cui X,Chen S,Bulbul A,Liu S,Yan Q

Wed May 01 00:00:00 EDT 2019

Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.

Journal of cellular physiology

Li Y,Zheng Q,Sun D,Cui X,Chen S,Bulbul A,Liu S,Yan Q

Wed May 01 00:00:00 EDT 2019

Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.

Journal of cellular physiology

Jing Z,Wang C,Yang Q,Wei X,Jin Y,Meng Q,Liu Q,Liu Z,Ma X,Liu K,Sun H,Liu M

Mon Apr 01 00:00:00 EDT 2019

Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro.

Journal of cellular physiology

Jing Z,Wang C,Yang Q,Wei X,Jin Y,Meng Q,Liu Q,Liu Z,Ma X,Liu K,Sun H,Liu M

Mon Apr 01 00:00:00 EDT 2019

1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.

Journal of cellular physiology

Fan J,Wu M,Wang J,Ren D,Zhao J,Yang G

Wed May 01 00:00:00 EDT 2019

1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.

Journal of cellular physiology

Fan J,Wu M,Wang J,Ren D,Zhao J,Yang G

Wed May 01 00:00:00 EDT 2019

Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.

Journal of cellular physiology

Liu P,Zhang HM,Hu K,Zhou XF,Tang S

Thu Aug 01 00:00:00 EDT 2019

Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.

Journal of cellular physiology

Liu P,Zhang HM,Hu K,Zhou XF,Tang S

Thu Aug 01 00:00:00 EDT 2019

Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.

International immunopharmacology

He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B

Fri Mar 01 00:00:00 EST 2019

Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.

International immunopharmacology

He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B

Fri Mar 01 00:00:00 EST 2019

Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.

The Journal of pharmacy and pharmacology

Uslusoy F,Nazıroğlu M,Övey İS,Sönmez TT

Tue Jan 01 00:00:00 EST 2019

Hypericum perforatum L. supplementation protects sciatic nerve injury-induced apoptotic, inflammatory and oxidative damage to muscle, blood and brain in rats.

The Journal of pharmacy and pharmacology

Uslusoy F,Nazıroğlu M,Övey İS,Sönmez TT

Tue Jan 01 00:00:00 EST 2019

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.

Inflammation

Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Liu X,Sun H

Fri Feb 01 00:00:00 EST 2019

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.

Inflammation

Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Liu X,Sun H

Fri Feb 01 00:00:00 EST 2019

Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.

International journal of food sciences and nutrition

Ge M,Zhang L,Cao L,Xie C,Li X,Li Y,Meng Y,Chen Y,Wang X,Chen J,Zhang Q,Shao J,Zhong C

Thu Aug 01 00:00:00 EDT 2019

Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.

International journal of food sciences and nutrition

Ge M,Zhang L,Cao L,Xie C,Li X,Li Y,Meng Y,Chen Y,Wang X,Chen J,Zhang Q,Shao J,Zhong C

Thu Aug 01 00:00:00 EDT 2019

Synthesized glucocorticoid-induced leucine zipper peptide inhibits photoreceptor apoptosis and protects retinal function in light-induced retinal degeneration model.

Clinical & experimental ophthalmology

Gu R,Tang W,Lei B,Jiang C,Song F,Xu G

Mon Jul 01 00:00:00 EDT 2019

Synthesized glucocorticoid-induced leucine zipper peptide inhibits photoreceptor apoptosis and protects retinal function in light-induced retinal degeneration model.

Clinical & experimental ophthalmology

Gu R,Tang W,Lei B,Jiang C,Song F,Xu G

Mon Jul 01 00:00:00 EDT 2019

Knockdown MTMR14 promotes cell apoptosis and inhibits migration in liver cancer cells.

Gene

Li Z,Rong L,Lian H,Cheng J,Wu X,Li X

Fri Apr 05 00:00:00 EDT 2019

Knockdown MTMR14 promotes cell apoptosis and inhibits migration in liver cancer cells.

Gene

Li Z,Rong L,Lian H,Cheng J,Wu X,Li X

Fri Apr 05 00:00:00 EDT 2019

Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.

Biochemical and biophysical research communications

Zhang Y,Li Q,Yu S,Zhu C,Zhang Z,Cao H,Xu J

Tue Feb 12 00:00:00 EST 2019

Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.

Biochemical and biophysical research communications

Zhang Y,Li Q,Yu S,Zhu C,Zhang Z,Cao H,Xu J

Tue Feb 12 00:00:00 EST 2019

Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.

ACS applied materials & interfaces

Shang Y,Wang Q,Wu B,Zhao Q,Li J,Huang X,Chen W,Gui R

Wed Aug 07 00:00:00 EDT 2019

The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.

Cancer management and research

Li T,Li L,Wu X,Tian K,Wang Y

Fri Apr 08 00:00:00 EDT 2022

Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.

British journal of pharmacology

Mao Z,Han X,Chen D,Xu Y,Xu L,Yin L,Sun H,Qi Y,Fang L,Liu K,Peng J

Mon Apr 01 00:00:00 EDT 2019

Knockdown of METTL14 inhibits the growth and invasion of cervical cancer.

Translational cancer research

Geng F,Fan MJ,Li J,Liang SM,Li CY,Li N

Tue Oct 01 00:00:00 EDT 2019

Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.

Journal of Cancer

Tian N,Shangguan W,Zhou Z,Yao Y,Fan C,Cai L

Thu Oct 01 00:00:00 EDT 2020

Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.

International journal of molecular sciences

Zhang L,Wang F,Zhang Q,Liang Q,Wang S,Xian M,Wang F

Tue Oct 29 00:00:00 EDT 2019

Iron chelation effect of curcumin and baicalein on aplastic anemia mouse model with iron overload.

Iranian journal of basic medical sciences

Dijiong W,Xiaowen W,Linlong X,Wenbin L,Huijin H,Baodong Y,Yuhong Z

Sat Jun 01 00:00:00 EDT 2019

Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.

American journal of translational research

Jiang J,Wang X,Gao G,Liu X,Chang H,Xiong R,Lu J,Sun Z

Thu Oct 01 00:00:00 EDT 2020

Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.

Journal of biomedical nanotechnology

Zhang D,Zhang J,Zeng J,Li Z,Zuo H,Huang C,Zhao X

Fri Feb 01 00:00:00 EST 2019

Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.

Pharmacological research

Guo J,Wang Q,Zhang Y,Sun W,Zhang S,Li Y,Wang J,Bao Y

Sun Sep 01 00:00:00 EDT 2019

The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.

American journal of translational research

Cao X,He Y,Li X,Xu Y,Liu X

Thu Oct 01 00:00:00 EDT 2020

SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.

OncoTargets and therapy

Chen Z,Lin J,Feng S,Chen X,Huang H,Wang C,Yu Y,He Y,Han S,Zheng L,Huang G

Fri Apr 08 00:00:00 EDT 2022

α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.

International journal of oncology

Sun J,Feng Y,Wang Y,Ji Q,Cai G,Shi L,Wang Y,Huang Y,Zhang J,Li Q

Wed May 01 00:00:00 EDT 2019

TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.

Oncology reports

Ye J,Chu C,Chen M,Shi Z,Gan S,Qu F,Pan X,Yang Q,Tian Y,Wang L,Yang W,Cui X

Fri Feb 01 00:00:00 EST 2019

Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca²⁺ Imbalance-Mediated Endoplasmic Reticulum Stress.

Oxidative medicine and cellular longevity

Cui J,Liu Y,Chang X,Gou W,Zhou X,Liu Z,Li Z,Wu Y,Zuo D

Mon Mar 04 00:00:00 EST 2019

Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis.

Cancer science

Song F,Wei M,Wang J,Liu Y,Guo M,Li X,Luo J,Zhou J,Wang M,Guo D,Chen L,Sun G

Wed May 01 00:00:00 EDT 2019

Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.

International immunopharmacology

Wang Y,Mao X,Chen H,Feng J,Yan M,Wang Y,Yu Y

Thu Aug 01 00:00:00 EDT 2019

Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.

Archives of oral biology

Ren H,Yang H,Xie M,Wen Y,Liu Q,Li X,Liu J,Xu H,Tang W,Wang M

Wed May 01 00:00:00 EDT 2019

Moderate activation of Wnt/β-catenin signaling promotes the survival of rat nucleus pulposus cells via regulating apoptosis, autophagy, and senescence.

Journal of cellular biochemistry

Li Z,Chen S,Chen S,Huang D,Ma K,Shao Z

Thu Aug 01 00:00:00 EDT 2019

The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.

Biological research

Cui C,Li Z,Wu D

Thu Jun 13 00:00:00 EDT 2019

PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway.

Cell & bioscience

Zou W,Niu C,Fu Z,Gong C

Thu Oct 01 00:00:00 EDT 2020

Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.

Pharmacological research

Wen J,Xu B,Sun Y,Lian M,Li Y,Lin Y,Chen D,Diao Y,Almoiliqy M,Wang L

Thu Aug 01 00:00:00 EDT 2019

Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.

Journal of Cancer

Wu D,Li M,Gao Y,Tian W,Li J,Zhang Q,Liu Z,Zheng M,Wang H,Wang J,Teng T,Zhang L,Ji X,Xie Z,Ji A,Li Y

Tue Sep 29 00:00:00 EDT 2020

Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway.

Biological research

Li L,Liu M,Zhang Z,Zhang W,Liu N,Sheng X,Wei P

Wed Feb 27 00:00:00 EST 2019

Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.

Phytotherapy research : PTR

Zhang Q,Cao WS,Wang XQ,Zhang M,Lu XM,Chen JQ,Chen Y,Ge MM,Zhong CY,Han HY

Tue Oct 01 00:00:00 EDT 2019

Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.

Oncology reports

Zhang X,Yang X,Zhu S,Li Q,Zou N

Fri Mar 01 00:00:00 EST 2019

TGF-β1 reduces the oxidative stress-induced autophagy and apoptosis in rat annulus fibrosus cells through the ERK signaling pathway.

Journal of orthopaedic surgery and research

Ni B,Shen H,Wang W,Lu H,Jiang L

Mon Jul 29 00:00:00 EDT 2019

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.

International journal of molecular sciences

Shah SZA,Zhao D,Taglialatela G,Hussain T,Dong H,Sabir N,Mangi MH,Wu W,Lai M,Zhang X,Duan Y,Wang L,Zhou X,Yang L

Wed Mar 06 00:00:00 EST 2019

Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lu L,Chen G,Yang J,Ma Z,Yang Y,Hu Y,Lu Y,Cao Z,Wang Y,Wang X

Mon Apr 01 00:00:00 EDT 2019

GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA_AR signaling and the AMPK-autophagy pathway.

Food & function

Xia Y,Chen S,Zhao Y,Chen S,Huang R,Zhu G,Yin Y,Ren W,Deng J

Fri Nov 01 00:00:00 EDT 2019

Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.

Pharmacological research

Yang Q,Wang C,Jin Y,Ma X,Xie T,Wang J,Liu K,Sun H

Tue Oct 01 00:00:00 EDT 2019

VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells.

International journal of molecular sciences

Zhi F,Zhou D,Bai F,Li J,Xiang C,Zhang G,Jin Y,Wang A

Thu Aug 22 00:00:00 EDT 2019

A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.

Cancer letters

Dong Q,Yang B,Han JG,Zhang MM,Liu W,Zhang X,Yu HL,Liu ZG,Zhang SH,Li T,Wu DD,Ji XY,Duan SF

Sun Jul 28 00:00:00 EDT 2019

HBOA ameliorates CCl₄-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Sun X,Huang X,Zhu X,Liu L,Mo S,Wang H,Wei X,Lu S,Bai F,Wang D,Lin X,Lin J

Mon Jul 01 00:00:00 EDT 2019

Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.

Molecular medicine reports

Yue G,Chen C,Bai L,Wang G,Huang Y,Wang Y,Cui H,Xiao Y

Fri Nov 01 00:00:00 EDT 2019

Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.

Life sciences

Li F,Zhang Y,Lu X,Shi J,Gong Q

Tue Oct 01 00:00:00 EDT 2019

Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.

Cancer letters

Liu X,Lu Y,Xu Y,Hou S,Huang J,Wang B,Zhao J,Xia S,Fan S,Yu X,Du Y,Hou L,Li Z,Ding Z,An S,Huang B,Li L,Tang J,Ju J,Guan H,Song B

Tue Sep 10 00:00:00 EDT 2019

Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.

Apoptosis : an international journal on programmed cell death

Ma H,Yu Y,Wang M,Li Z,Xu H,Tian C,Zhang J,Ye X,Li X

Fri Feb 01 00:00:00 EST 2019

Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.

Apoptosis : an international journal on programmed cell death

Ma H,Yu Y,Wang M,Li Z,Xu H,Tian C,Zhang J,Ye X,Li X

Fri Feb 01 00:00:00 EST 2019

Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.

Apoptosis : an international journal on programmed cell death

Ma H,Yu Y,Wang M,Li Z,Xu H,Tian C,Zhang J,Ye X,Li X

Fri Feb 01 00:00:00 EST 2019

Protective effects of ethyl gallate on H₂O₂-induced mitochondrial dysfunction in PC12 cells.

Metabolic brain disease

Chen L,Wu X,Shen T,Wang X,Wang S,Wang J,Ren D

Mon Apr 01 00:00:00 EDT 2019

Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.

Oxidative medicine and cellular longevity

Qaed E,Wang J,Almoiliqy M,Song Y,Liu W,Chu P,Alademi S,Alademi M,Li H,Alshwmi M,Al-Azab M,Ahsan A,Mahdi S,Han G,Niu M,Ali A,Shopit A,Wang H,Li X,Qaid A,Ma X,Li T,Peng J,Ma J,Zhang J,Tang Z

Thu Jun 25 00:00:00 EDT 2020

Ubenimex induces apoptotic and autophagic cell death in rat GH3 and MMQ cells through the ROS/ERK pathway.

Drug design, development and therapy

Wang Y,Pang B,Zhang R,Fu Y,Pang Q

Tue Feb 25 00:00:00 EST 2020

The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.

PloS one

Liu H,Zhao J,Fu R,Zhu C,Fan D

Fri Jan 24 00:00:00 EST 2020

Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.

Molecular medicine reports

Ge LN,Yan L,Li C,Cheng K

Sun Sep 01 00:00:00 EDT 2019

Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.

Oncology reports

Yu H,Fu QR,Huang ZJ,Lin JY,Chen QX,Wang Q,Shen DY

Tue Jan 01 00:00:00 EST 2019

A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.

Toxicology and applied pharmacology

Shen J,Wang J,Du J,Wang L,Zhou X,Chang X,Li Z,Zhai X,Zuo D,Wu Y

Fri Nov 15 00:00:00 EST 2019

Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.

International immunopharmacology

Yu Q,Wu L,Liu T,Li S,Feng J,Mao Y,Fan X,Guo C,Wu J

Wed May 01 00:00:00 EDT 2019

The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.

Frontiers in endocrinology

Suo L,Chang X,Xu N,Ji H

Tue Feb 25 00:00:00 EST 2020

Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.

Journal of Cancer

Zhang Q,Meng X,Qin G,Xue X,Dang N

Fri Oct 06 00:00:00 EDT 2023

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.

OncoTargets and therapy

Shi S,Zheng G,Yang C,Chen X,Yan Q,Jiang F,Jiang X,Xin Y,Jiang G

Wed Apr 13 00:00:00 EDT 2022

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.

OncoTargets and therapy

Shi S,Zheng G,Yang C,Chen X,Yan Q,Jiang F,Jiang X,Xin Y,Jiang G

Wed Apr 13 00:00:00 EDT 2022

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.

OncoTargets and therapy

Shi S,Zheng G,Yang C,Chen X,Yan Q,Jiang F,Jiang X,Xin Y,Jiang G

Wed Apr 13 00:00:00 EDT 2022

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells.

OncoTargets and therapy

Shi S,Zheng G,Yang C,Chen X,Yan Q,Jiang F,Jiang X,Xin Y,Jiang G

Wed Apr 13 00:00:00 EDT 2022

H₂S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.

Aging

Zhang Y,Gao J,Sun W,Wen X,Xi Y,Wang Y,Wei C,Xu C,Li H

Tue Mar 26 00:00:00 EDT 2019

Mitochondrial Pathway Is Involved in Advanced Glycation End Products-Induced Apoptosis of Rabbit Annulus Fibrosus Cells.

Spine

Hu Y,Shao Z,Cai X,Liu Y,Shen M,Yao Y,Yuan T,Wang W,Ding F,Xiong L

Wed May 15 00:00:00 EDT 2019

Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury.

Cell death & disease

Liu Z,Li T,Zhu F,Deng S,Li X,He Y

Thu Mar 07 00:00:00 EST 2019

Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.

Food science & nutrition

Hua S,Liu J,Zhang Y,Li J,Zhang X,Dong L,Zhao Y,Fu X

Fri Nov 01 00:00:00 EDT 2019

Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.

European review for medical and pharmacological sciences

Li XY,Liu YR,Zhou JH,Li W,Guo HH,Ma HP

Mon Apr 01 00:00:00 EDT 2019

Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.

Scientific reports

Zhang J,Yao D,Song Y,Pan Y,Zhu L,Bai Y,Xu Y,Zhang J,Shao C

Wed Oct 23 00:00:00 EDT 2019

Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.

Mediators of inflammation

Wang W,Wu L,Li J,Ji J,Chen K,Yu Q,Li S,Feng J,Liu T,Zhang J,Chen J,Zhou Y,Mao Y,Wang F,Dai W,Fan X,Guo C,Wu J

Mon Feb 24 00:00:00 EST 2020

Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.

Toxicology

Wang R,Li D,Ouyang J,Tian X,Zhao Y,Peng X,Li S,Yu G,Yang J

Sat Jun 15 00:00:00 EDT 2019

Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer.

Signal transduction and targeted therapy

Sun X,Zhan L,Chen Y,Wang G,He L,Wang Q,Zhou F,Yang F,Wu J,Wu Y,Xing J,He X,Huang Q

Mon Feb 01 00:00:00 EST 2021

Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer.

Signal transduction and targeted therapy

Sun X,Zhan L,Chen Y,Wang G,He L,Wang Q,Zhou F,Yang F,Wu J,Wu Y,Xing J,He X,Huang Q

Mon Feb 01 00:00:00 EST 2021

Therapeutic effects of the novel subtype-selective histone deacetylase inhibitor chidamide on myeloma-associated bone disease.

Haematologica

He J,Chen Q,Gu H,Chen J,Zhang E,Guo X,Huang X,Yan H,He D,Yang Y,Zhao Y,Wang G,He H,Yi Q,Cai Z

Wed Aug 01 00:00:00 EDT 2018

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.

Cancer letters

Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J

Wed Feb 28 00:00:00 EST 2018

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.

Cancer letters

Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J

Wed Feb 28 00:00:00 EST 2018

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.

Cancer letters

Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J

Wed Feb 28 00:00:00 EST 2018

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.

Cancer letters

Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J

Wed Feb 28 00:00:00 EST 2018

The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

Oncogene

Shi J,Li F,Yao X,Mou T,Xu Z,Han Z,Chen S,Li W,Yu J,Qi X,Liu H,Li G

Tue May 01 00:00:00 EDT 2018

The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

Oncogene

Shi J,Li F,Yao X,Mou T,Xu Z,Han Z,Chen S,Li W,Yu J,Qi X,Liu H,Li G

Tue May 01 00:00:00 EDT 2018

Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.

Cell proliferation

Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y

Wed Aug 01 00:00:00 EDT 2018

Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.

Cell proliferation

Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y

Wed Aug 01 00:00:00 EDT 2018

MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.

Cellular & molecular biology letters

Tian ZQ,Jiang H,Lu ZB

Mon Oct 29 00:00:00 EDT 2018

MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1.

Cellular & molecular biology letters

Tian ZQ,Jiang H,Lu ZB

Mon Oct 29 00:00:00 EDT 2018

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.

Free radical biology & medicine

Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z

Sun May 20 00:00:00 EDT 2018

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.

Free radical biology & medicine

Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z

Sun May 20 00:00:00 EDT 2018

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.

Free radical biology & medicine

Li H,Tang Z,Chu P,Song Y,Yang Y,Sun B,Niu M,Qaed E,Shopit A,Han G,Ma X,Peng J,Hu M,Tang Z

Sun May 20 00:00:00 EDT 2018

Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.

International journal of biological macromolecules

Zhang Y,Li H,Yang X,Jin G,Zhang Y

Fri Jun 01 00:00:00 EDT 2018

Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.

International journal of biological macromolecules

Zhang Y,Li H,Yang X,Jin G,Zhang Y

Fri Jun 01 00:00:00 EDT 2018

Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.

International journal of biological macromolecules

Zhang Y,Li H,Yang X,Jin G,Zhang Y

Fri Jun 01 00:00:00 EDT 2018

Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.

International journal of biological macromolecules

Zhang Y,Li H,Yang X,Jin G,Zhang Y

Fri Jun 01 00:00:00 EDT 2018

Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C

Sun Jul 01 00:00:00 EDT 2018

Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C

Sun Jul 01 00:00:00 EDT 2018

Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.

Oxidative medicine and cellular longevity

Zhang Y,Wang C,Jin Y,Yang Q,Meng Q,Liu Q,Dai Y,Cai L,Liu Z,Liu K,Sun H

Mon Oct 22 00:00:00 EDT 2018

Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link.

Oxidative medicine and cellular longevity

Zhang Y,Wang C,Jin Y,Yang Q,Meng Q,Liu Q,Dai Y,Cai L,Liu Z,Liu K,Sun H

Mon Oct 22 00:00:00 EDT 2018

Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.

Oxidative medicine and cellular longevity

Zhang GY,Lu D,Duan SF,Gao YR,Liu SY,Hong Y,Dong PZ,Chen YG,Li T,Wang DY,Cheng XS,He F,Wei JS,Li GY,Zhang QY,Wu DD,Ji XY

Mon Oct 15 00:00:00 EDT 2018

Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.

Oxidative medicine and cellular longevity

Zhang GY,Lu D,Duan SF,Gao YR,Liu SY,Hong Y,Dong PZ,Chen YG,Li T,Wang DY,Cheng XS,He F,Wei JS,Li GY,Zhang QY,Wu DD,Ji XY

Mon Oct 15 00:00:00 EDT 2018

8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.

Life sciences

Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X

Mon Jan 01 00:00:00 EST 2018

8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.

Life sciences

Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X

Mon Jan 01 00:00:00 EST 2018

8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.

Life sciences

Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X

Mon Jan 01 00:00:00 EST 2018

8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.

Life sciences

Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X

Mon Jan 01 00:00:00 EST 2018

UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.

Journal of cellular physiology

Huang Y,Hu Z

Sat Sep 01 00:00:00 EDT 2018

UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.

Journal of cellular physiology

Huang Y,Hu Z

Sat Sep 01 00:00:00 EDT 2018

Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.

Journal of cellular physiology

Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z

Mon Jan 01 00:00:00 EST 2018

Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.

Journal of cellular physiology

Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z

Mon Jan 01 00:00:00 EST 2018

Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.

Phytotherapy research : PTR

Chen Y,Li Y,Wang XQ,Meng Y,Zhang Q,Zhu JY,Chen JQ,Cao WS,Wang XQ,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY

Sat Dec 01 00:00:00 EST 2018

Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.

Phytotherapy research : PTR

Chen Y,Li Y,Wang XQ,Meng Y,Zhang Q,Zhu JY,Chen JQ,Cao WS,Wang XQ,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY

Sat Dec 01 00:00:00 EST 2018

Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.

American journal of cancer research

Pan B,Zang J,He J,Wang Z,Liu L

Wed Mar 30 00:00:00 EDT 2022

Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.

American journal of cancer research

Pan B,Zang J,He J,Wang Z,Liu L

Wed Mar 30 00:00:00 EDT 2022

Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.

International immunopharmacology

Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L

Thu Mar 01 00:00:00 EST 2018

Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.

International immunopharmacology

Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L

Thu Mar 01 00:00:00 EST 2018

Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis.

Apoptosis : an international journal on programmed cell death

Chen S,Lv X,Hu B,Zhao L,Li S,Li Z,Qing X,Liu H,Xu J,Shao Z

Fri Jun 01 00:00:00 EDT 2018

Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis.

Apoptosis : an international journal on programmed cell death

Chen S,Lv X,Hu B,Zhao L,Li S,Li Z,Qing X,Liu H,Xu J,Shao Z

Fri Jun 01 00:00:00 EDT 2018

Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.

Journal of ethnopharmacology

Zhang J,Liu L,Wang J,Ren B,Zhang L,Li W

Sun Jul 15 00:00:00 EDT 2018

Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells.

Journal of ethnopharmacology

Zhang J,Liu L,Wang J,Ren B,Zhang L,Li W

Sun Jul 15 00:00:00 EDT 2018

Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.

Chemico-biological interactions

Liu L,Wang Q,Mao J,Qin T,Sun Y,Yang J,Han Y,Li L,Li Q

Tue Dec 25 00:00:00 EST 2018

Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.

Chemico-biological interactions

Liu L,Wang Q,Mao J,Qin T,Sun Y,Yang J,Han Y,Li L,Li Q

Tue Dec 25 00:00:00 EST 2018

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.

Mediators of inflammation

Yu Q,Liu T,Li S,Feng J,Wu L,Wang W,Chen K,Xia Y,Niu P,Xu L,Wang F,Dai W,Zhou Y,Guo C

Fri Apr 19 00:00:00 EDT 2019

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.

Mediators of inflammation

Yu Q,Liu T,Li S,Feng J,Wu L,Wang W,Chen K,Xia Y,Niu P,Xu L,Wang F,Dai W,Zhou Y,Guo C

Fri Apr 19 00:00:00 EDT 2019

Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.

Journal of cellular biochemistry

Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M

Tue May 01 00:00:00 EDT 2018

Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.

Journal of cellular biochemistry

Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M

Tue May 01 00:00:00 EDT 2018

Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.

Clinical implant dentistry and related research

Che C,Liu J,Yang J,Ma L,Bai N,Zhang Q

Fri Jun 01 00:00:00 EDT 2018

Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.

Clinical implant dentistry and related research

Che C,Liu J,Yang J,Ma L,Bai N,Zhang Q

Fri Jun 01 00:00:00 EDT 2018

Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis.

Acta biochimica et biophysica Sinica

Hu J,Wang H,Gu J,Liu X,Zhou X

Mon Oct 01 00:00:00 EDT 2018

Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis.

Acta biochimica et biophysica Sinica

Hu J,Wang H,Gu J,Liu X,Zhou X

Mon Oct 01 00:00:00 EDT 2018

Toosendanin induces caspase-dependent apoptosis through the p38 MAPK pathway in human gastric cancer cells.

Biochemical and biophysical research communications

Zhou Q,Wu X,Wen C,Wang H,Wang H,Liu H,Peng J

Sat Oct 20 00:00:00 EDT 2018

Toosendanin induces caspase-dependent apoptosis through the p38 MAPK pathway in human gastric cancer cells.

Biochemical and biophysical research communications

Zhou Q,Wu X,Wen C,Wang H,Wang H,Liu H,Peng J

Sat Oct 20 00:00:00 EDT 2018

Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.

Biochemical and biophysical research communications

Wang J,Li H,Wang X,Shen T,Wang S,Ren D

Sat Nov 10 00:00:00 EST 2018

Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.

Biochemical and biophysical research communications

Wang J,Li H,Wang X,Shen T,Wang S,Ren D

Sat Nov 10 00:00:00 EST 2018

Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.

Cancer chemotherapy and pharmacology

Zhang Q,Li XT,Chen Y,Chen JQ,Zhu JY,Meng Y,Wang XQ,Li Y,Geng SS,Xie CF,Wu JS,Zhong CY,Han HY

Fri Jun 01 00:00:00 EDT 2018

Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.

Cancer chemotherapy and pharmacology

Zhang Q,Li XT,Chen Y,Chen JQ,Zhu JY,Meng Y,Wang XQ,Li Y,Geng SS,Xie CF,Wu JS,Zhong CY,Han HY

Fri Jun 01 00:00:00 EDT 2018

Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.

Cornea

Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G

Sat Dec 01 00:00:00 EST 2018

Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.

Cornea

Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G

Sat Dec 01 00:00:00 EST 2018

Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway.

Oncology letters

Zhang H,Cao Y,Chen Y,Li G,Yu H

Sun Apr 01 00:00:00 EDT 2018

Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway.

Oncology letters

Zhang H,Cao Y,Chen Y,Li G,Yu H

Sun Apr 01 00:00:00 EDT 2018

Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.

PeerJ

Hu XN,Wang JF,Huang YQ,Wang Z,Dong FY,Ma HF,Bao ZJ

Fri Mar 18 00:00:00 EDT 2022

Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study.

PeerJ

Hu XN,Wang JF,Huang YQ,Wang Z,Dong FY,Ma HF,Bao ZJ

Fri Mar 18 00:00:00 EDT 2022

Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.

FEBS open bio

Lai X,Su W,Zhao H,Yang S,Zeng T,Wu W,Wang D

Tue May 01 00:00:00 EDT 2018

Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.

FEBS open bio

Lai X,Su W,Zhao H,Yang S,Zeng T,Wu W,Wang D

Tue May 01 00:00:00 EDT 2018

The proliferation of colorectal cancer cells is suppressed by silencing of EIF3H.

Bioscience, biotechnology, and biochemistry

Yu G,Liao J,Wu J,Ding J,Zhang L

Mon Oct 01 00:00:00 EDT 2018

Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.

PloS one

Zhang HM,Liu P,Jiang C,Jin XQ,Liu RN,Li SQ,Zhao Y

Tue May 22 00:00:00 EDT 2018

Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.

PloS one

Zhang HM,Liu P,Jiang C,Jin XQ,Liu RN,Li SQ,Zhao Y

Tue May 22 00:00:00 EDT 2018

Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.

Journal of experimental & clinical cancer research : CR

Qin T,Li B,Feng X,Fan S,Liu L,Liu D,Mao J,Lu Y,Yang J,Yu X,Zhang Q,Zhang J,Song B,Li M,Li L

Tue Nov 27 00:00:00 EST 2018

Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.

Journal of experimental & clinical cancer research : CR

Qin T,Li B,Feng X,Fan S,Liu L,Liu D,Mao J,Lu Y,Yang J,Yu X,Zhang Q,Zhang J,Song B,Li M,Li L

Tue Nov 27 00:00:00 EST 2018

PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.

BMC cancer

Wu DD,Gao YR,Li T,Wang DY,Lu D,Liu SY,Hong Y,Ning HB,Liu JP,Shang J,Shi JF,Wei JS,Ji XY

Wed May 02 00:00:00 EDT 2018

PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.

BMC cancer

Wu DD,Gao YR,Li T,Wang DY,Lu D,Liu SY,Hong Y,Ning HB,Liu JP,Shang J,Shi JF,Wei JS,Ji XY

Wed May 02 00:00:00 EDT 2018

HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zhai E,Liang W,Lin Y,Huang L,He X,Cai S,Chen J,Zhang N,Li J,Zhang Q,He Y,Zeng Z,Chen M,Xu L,Peng S

Tue Jul 24 00:00:00 EDT 2018

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.

Cancers

Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH

Mon Dec 31 00:00:00 EST 2018

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.

Cancers

Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH

Mon Dec 31 00:00:00 EST 2018

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.

Cancers

Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH

Mon Dec 31 00:00:00 EST 2018

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.

Cancers

Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH

Mon Dec 31 00:00:00 EST 2018

Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.

Medical science monitor : international medical journal of experimental and clinical research

Liu S,Liu B

Fri Mar 09 00:00:00 EST 2018

Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.

Medical science monitor : international medical journal of experimental and clinical research

Liu S,Liu B

Fri Mar 09 00:00:00 EST 2018

Study on the potential way of hepatic cytotoxicity of N,N-dimethylformamide.

Journal of biochemical and molecular toxicology

Li S,Wang C

Sat Sep 01 00:00:00 EDT 2018

Exogenous hydrogen sulfide protects human umbilical vein endothelial cells against high glucose‑induced injury by inhibiting the necroptosis pathway.

International journal of molecular medicine

Lin J,Chen M,Liu D,Guo R,Lin K,Deng H,Zhi X,Zhang W,Feng J,Wu W

Thu Mar 01 00:00:00 EST 2018

Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.

Frontiers in pharmacology

Mao J,Yi M,Wang R,Huang Y,Chen M

Sat Apr 09 00:00:00 EDT 2022

Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.

Frontiers in pharmacology

Mao J,Yi M,Wang R,Huang Y,Chen M

Sat Apr 09 00:00:00 EDT 2022

Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zheng Q,Zhou F,Cui X,Liu M,Li Y,Liu S,Tan J,Yan Q

Fri Aug 17 00:00:00 EDT 2018

Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zheng Q,Zhou F,Cui X,Liu M,Li Y,Liu S,Tan J,Yan Q

Fri Aug 17 00:00:00 EDT 2018

Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.

Cancer medicine

Wu Z,Zhu Q,Yin Y,Kang D,Cao R,Tian Q,Zhang Y,Lu S,Liu P

Sun Apr 01 00:00:00 EDT 2018

Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.

Cancer medicine

Wu Z,Zhu Q,Yin Y,Kang D,Cao R,Tian Q,Zhang Y,Lu S,Liu P

Sun Apr 01 00:00:00 EDT 2018

High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.

Journal of translational medicine

Zhang ZF,Zhang HR,Zhang QY,Lai SY,Feng YZ,Zhou Y,Zheng SR,Shi R,Zhou JY

Fri Jan 19 00:00:00 EST 2018

High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.

Journal of translational medicine

Zhang ZF,Zhang HR,Zhang QY,Lai SY,Feng YZ,Zhou Y,Zheng SR,Shi R,Zhou JY

Fri Jan 19 00:00:00 EST 2018

Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.

Chemical research in toxicology

Dong W,Yang B,Wang Y,Yuan J,Fan Y,Song E,Song Y

Mon Nov 19 00:00:00 EST 2018

Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.

Journal of agricultural and food chemistry

Han B,Jiang P,Liu W,Xu H,Li Y,Li Z,Ma H,Yu Y,Li X,Ye X

Wed Jun 20 00:00:00 EDT 2018

Neuroprotective effect of polysaccharides from Gastrodia elata blume against corticosterone‑induced apoptosis in PC12 cells via inhibition of the endoplasmic reticulum stress‑mediated pathway.

Molecular medicine reports

Zhou B,Tan J,Zhang C,Wu Y

Mon Jan 01 00:00:00 EST 2018

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.

Journal of pineal research

Gao Y,Xiao X,Zhang C,Yu W,Guo W,Zhang Z,Li Z,Feng X,Hao J,Zhang K,Xiao B,Chen M,Huang W,Xiong S,Wu X,Deng W

Wed Mar 01 00:00:00 EST 2017

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.

Journal of pineal research

Gao Y,Xiao X,Zhang C,Yu W,Guo W,Zhang Z,Li Z,Feng X,Hao J,Zhang K,Xiao B,Chen M,Huang W,Xiong S,Wu X,Deng W

Wed Mar 01 00:00:00 EST 2017

The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.

Chemosphere

Li S,Zhao H,Wang Y,Shao Y,Li J,Liu J,Xing M

Fri Dec 01 00:00:00 EST 2017

The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.

Chemosphere

Li S,Zhao H,Wang Y,Shao Y,Li J,Liu J,Xing M

Fri Dec 01 00:00:00 EST 2017

7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhu Y,Jiang Y,Shi L,Du L,Xu X,Wang E,Sun Y,Guo X,Zou B,Wang H,Wang C,Sun L,Zhen Y

Wed Mar 01 00:00:00 EST 2017

7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhu Y,Jiang Y,Shi L,Du L,Xu X,Wang E,Sun Y,Guo X,Zou B,Wang H,Wang C,Sun L,Zhen Y

Wed Mar 01 00:00:00 EST 2017

Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Jing Z,Lv J,Zhang Z,Lin J,Cao X,Zhao Z,Liu P,Mao W

Wed Nov 01 00:00:00 EDT 2017

Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Jing Z,Lv J,Zhang Z,Lin J,Cao X,Zhao Z,Liu P,Mao W

Wed Nov 01 00:00:00 EDT 2017

Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Jing Z,Lv J,Zhang Z,Lin J,Cao X,Zhao Z,Liu P,Mao W

Wed Nov 01 00:00:00 EDT 2017

Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Jing Z,Lv J,Zhang Z,Lin J,Cao X,Zhao Z,Liu P,Mao W

Wed Nov 01 00:00:00 EDT 2017

LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1.

Acta pharmacologica Sinica

Wang ZB,Zhang S,Li Y,Wang RM,Tong LC,Wang Y,Liu WY,Su DF,Tu Y,Zhang LC,Li L

Sat Jul 01 00:00:00 EDT 2017

LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1.

Acta pharmacologica Sinica

Wang ZB,Zhang S,Li Y,Wang RM,Tong LC,Wang Y,Liu WY,Su DF,Tu Y,Zhang LC,Li L

Sat Jul 01 00:00:00 EDT 2017

Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.

Drug delivery

Hu JB,Song GL,Liu D,Li SJ,Wu JH,Kang XQ,Qi J,Jin FY,Wang XJ,Xu XL,Ying XY,Yu L,You J,Du YZ

Wed Nov 01 00:00:00 EDT 2017

Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.

Drug delivery

Hu JB,Song GL,Liu D,Li SJ,Wu JH,Kang XQ,Qi J,Jin FY,Wang XJ,Xu XL,Ying XY,Yu L,You J,Du YZ

Wed Nov 01 00:00:00 EDT 2017

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.

Phytotherapy research : PTR

Zhu JY,Yang X,Chen Y,Jiang Y,Wang SJ,Li Y,Wang XQ,Meng Y,Zhu MM,Ma X,Huang C,Wu R,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY

Sat Apr 01 00:00:00 EDT 2017

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.

Phytotherapy research : PTR

Zhu JY,Yang X,Chen Y,Jiang Y,Wang SJ,Li Y,Wang XQ,Meng Y,Zhu MM,Ma X,Huang C,Wu R,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY

Sat Apr 01 00:00:00 EDT 2017

miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.

The Journal of nutritional biochemistry

Zhu J,Wang S,Chen Y,Li X,Jiang Y,Yang X,Li Y,Wang X,Meng Y,Zhu M,Ma X,Huang C,Wu R,Xie C,Geng S,Wu J,Zhong C,Han H

Thu Jun 01 00:00:00 EDT 2017

miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.

The Journal of nutritional biochemistry

Zhu J,Wang S,Chen Y,Li X,Jiang Y,Yang X,Li Y,Wang X,Meng Y,Zhu M,Ma X,Huang C,Wu R,Xie C,Geng S,Wu J,Zhong C,Han H

Thu Jun 01 00:00:00 EDT 2017

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Shah SZA,Zhao D,Taglialatela G,Khan SH,Hussain T,Dong H,Lai M,Zhou X,Yang L

Sat Apr 01 00:00:00 EDT 2017

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Shah SZA,Zhao D,Taglialatela G,Khan SH,Hussain T,Dong H,Lai M,Zhou X,Yang L

Sat Apr 01 00:00:00 EDT 2017

Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.

Vascular pharmacology

Chu P,Han G,Ahsan A,Sun Z,Liu S,Zhang Z,Sun B,Song Y,Lin Y,Peng J,Tang Z

Sat Apr 01 00:00:00 EDT 2017

Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.

Vascular pharmacology

Chu P,Han G,Ahsan A,Sun Z,Liu S,Zhang Z,Sun B,Song Y,Lin Y,Peng J,Tang Z

Sat Apr 01 00:00:00 EDT 2017

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.

International immunopharmacology

Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B

Mon May 01 00:00:00 EDT 2017

Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.

International immunopharmacology

Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B

Mon May 01 00:00:00 EDT 2017

Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.

International immunopharmacology

Yuan K,Zhao G,Che C,Li C,Lin J,Zhu G,He K

Wed Nov 01 00:00:00 EDT 2017

Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.

International immunopharmacology

Yuan K,Zhao G,Che C,Li C,Lin J,Zhu G,He K

Wed Nov 01 00:00:00 EDT 2017

EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.

Apoptosis : an international journal on programmed cell death

Liu S,Sun Z,Chu P,Li H,Ahsan A,Zhou Z,Zhang Z,Sun B,Wu J,Xi Y,Han G,Lin Y,Peng J,Tang Z

Mon May 01 00:00:00 EDT 2017

EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways.

Apoptosis : an international journal on programmed cell death

Liu S,Sun Z,Chu P,Li H,Ahsan A,Zhou Z,Zhang Z,Sun B,Wu J,Xi Y,Han G,Lin Y,Peng J,Tang Z

Mon May 01 00:00:00 EDT 2017

Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.

Apoptosis : an international journal on programmed cell death

Xie XC,Zhao N,Xu QH,Yang X,Xia WK,Chen Q,Wang M,Fei X

Thu Jun 01 00:00:00 EDT 2017

Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.

Apoptosis : an international journal on programmed cell death

Xie XC,Zhao N,Xu QH,Yang X,Xia WK,Chen Q,Wang M,Fei X

Thu Jun 01 00:00:00 EDT 2017

Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.

International journal of molecular medicine

Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H

Sat Apr 01 00:00:00 EDT 2017

Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.

International journal of molecular medicine

Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H

Sat Apr 01 00:00:00 EDT 2017

Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.

Journal of cellular and molecular medicine

Liu N,Wu J,Zhang L,Gao Z,Sun Y,Yu M,Zhao Y,Dong S,Lu F,Zhang W

Fri Dec 01 00:00:00 EST 2017

Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.

Journal of cellular and molecular medicine

Liu N,Wu J,Zhang L,Gao Z,Sun Y,Yu M,Zhao Y,Dong S,Lu F,Zhang W

Fri Dec 01 00:00:00 EST 2017

Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y

Wed Nov 15 00:00:00 EST 2017

Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y

Wed Nov 15 00:00:00 EST 2017

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.

Investigative ophthalmology & visual science

Gu R,Tang W,Lei B,Ding X,Jiang C,Xu G

Sat Jul 01 00:00:00 EDT 2017

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.

Investigative ophthalmology & visual science

Gu R,Tang W,Lei B,Ding X,Jiang C,Xu G

Sat Jul 01 00:00:00 EDT 2017

Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.

Cell biology international

Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z

Fri Dec 01 00:00:00 EST 2017

Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.

Cell biology international

Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z

Fri Dec 01 00:00:00 EST 2017

Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Cellular and molecular neurobiology

Khan SH,Zhao D,Shah SZ,Hassan MF,Zhu T,Song Z,Zhou X,Yang L

Mon May 01 00:00:00 EDT 2017

Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Cellular and molecular neurobiology

Khan SH,Zhao D,Shah SZ,Hassan MF,Zhu T,Song Z,Zhou X,Yang L

Mon May 01 00:00:00 EDT 2017

PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway.

Journal of Alzheimer's disease : JAD

Liu LS,Bai XQ,Gao Y,Wu Q,Ren Z,Li Q,Pan LH,He NY,Peng J,Tang ZH

Fri Aug 25 00:00:00 EDT 2017

PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway.

Journal of Alzheimer's disease : JAD

Liu LS,Bai XQ,Gao Y,Wu Q,Ren Z,Li Q,Pan LH,He NY,Peng J,Tang ZH

Fri Aug 25 00:00:00 EDT 2017

Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.

Gene

Zhang S,Yao F,Jing T,Zhang M,Zhao W,Zou X,Sui L,Hou L

Sun Sep 10 00:00:00 EDT 2017

Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.

Acta biochimica et biophysica Sinica

Sheng N,Yan L,You W,Tan G,Gong J,Chen H,Yang Y,Hu L,Wang Z

Sun Oct 01 00:00:00 EDT 2017

Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.

Acta biochimica et biophysica Sinica

Sheng N,Yan L,You W,Tan G,Gong J,Chen H,Yang Y,Hu L,Wang Z

Sun Oct 01 00:00:00 EDT 2017

Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats.

Molecular medicine reports

Liu M,Liu S,Tan W,Tang F,Long J,Li Z,Liang B,Chu C,Yang J

Fri Dec 01 00:00:00 EST 2017

Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats.

Molecular medicine reports

Liu M,Liu S,Tan W,Tang F,Long J,Li Z,Liang B,Chu C,Yang J

Fri Dec 01 00:00:00 EST 2017

Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.

Molecular medicine reports

He J,Shi J,Zhang K,Xue J,Li J,Yang J,Chen J,Wei J,Ren H,Liu X

Sat Apr 01 00:00:00 EDT 2017

Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.

Molecular medicine reports

He J,Shi J,Zhang K,Xue J,Li J,Yang J,Chen J,Wei J,Ren H,Liu X

Sat Apr 01 00:00:00 EDT 2017

Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.

Molecular medicine reports

Gao C,Zhou Y,Li H,Cong X,Jiang Z,Wang X,Cao R,Tian W

Fri Dec 01 00:00:00 EST 2017

Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro.

Molecular medicine reports

Gao C,Zhou Y,Li H,Cong X,Jiang Z,Wang X,Cao R,Tian W

Fri Dec 01 00:00:00 EST 2017

Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.

Biochemical and biophysical research communications

Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C

Sun Jan 01 00:00:00 EST 2017

Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.

Biochemical and biophysical research communications

Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C

Sun Jan 01 00:00:00 EST 2017

Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.

Biochemical and biophysical research communications

Wang D,Kong X,Li Y,Qian W,Ma J,Wang D,Yu D,Zhong C

Sat Nov 04 00:00:00 EDT 2017

Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.

Biochemical and biophysical research communications

Wang D,Kong X,Li Y,Qian W,Ma J,Wang D,Yu D,Zhong C

Sat Nov 04 00:00:00 EDT 2017

Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.

Biotechnology and applied biochemistry

Tan MJ,Cao XW,Li PF,Zhai YZ,Zhou Y,Liu YJ,Zhao J,Wang FJ

Wed Nov 01 00:00:00 EDT 2017

Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.

Biotechnology and applied biochemistry

Tan MJ,Cao XW,Li PF,Zhai YZ,Zhou Y,Liu YJ,Zhao J,Wang FJ

Wed Nov 01 00:00:00 EDT 2017

Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.

Audiology & neuro-otology

Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H

Fri Jul 27 00:00:00 EDT 2018

Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.

Audiology & neuro-otology

Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H

Fri Jul 27 00:00:00 EDT 2018

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.

Gastroenterology research and practice

Wu L,Zhang Q,Dai W,Li S,Feng J,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Zhou Y,Fan X,Guo C

Thu Mar 31 00:00:00 EDT 2022

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.

Gastroenterology research and practice

Wu L,Zhang Q,Dai W,Li S,Feng J,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Zhou Y,Fan X,Guo C

Thu Mar 31 00:00:00 EDT 2022

Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.

Scientific reports

Huang T,Xiao Y,Yi L,Li L,Wang M,Tian C,Ma H,He K,Wang Y,Han B,Ye X,Li X

Mon Feb 06 00:00:00 EST 2017

Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.

Scientific reports

Huang T,Xiao Y,Yi L,Li L,Wang M,Tian C,Ma H,He K,Wang Y,Han B,Ye X,Li X

Mon Feb 06 00:00:00 EST 2017

Inhibited effects of CAPE-pNO₂ on cervical carcinoma in vivo and in vitro and its detected metabolites.

Oncotarget

Yao X,Tang H,Ren Q,Zhao X,Zuo H,Li Z

Tue Nov 07 00:00:00 EST 2017

Inhibited effects of CAPE-pNO₂ on cervical carcinoma in vivo and in vitro and its detected metabolites.

Oncotarget

Yao X,Tang H,Ren Q,Zhao X,Zuo H,Li Z

Tue Nov 07 00:00:00 EST 2017

Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.

Marine drugs

Wei H,Gao Z,Zheng L,Zhang C,Liu Z,Yang Y,Teng H,Hou L,Yin Y,Zou X

Thu Mar 16 00:00:00 EDT 2017

Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.

Marine drugs

Wei H,Gao Z,Zheng L,Zhang C,Liu Z,Yang Y,Teng H,Hou L,Yin Y,Zou X

Thu Mar 16 00:00:00 EDT 2017

Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.

International immunopharmacology

Peng Z,Gong X,Yang Y,Huang L,Zhang Q,Zhang P,Wan R,Zhang B

Wed Nov 01 00:00:00 EDT 2017

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.

Oncotarget

Xue C,Wang C,Sun Y,Meng Q,Liu Z,Huo X,Sun P,Sun H,Ma X,Ma X,Peng J,Liu K

Tue Jan 31 00:00:00 EST 2017

The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.

Scientific reports

Xu S,Niu P,Chen K,Xia Y,Yu Q,Liu N,Li J,Li S,Wu L,Feng J,Wang W,Lu X,Liu T,Wang F,Dai W,Fan X,Mo W,Xu L,Guo C

Thu Nov 09 00:00:00 EST 2017

The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.

Scientific reports

Xu S,Niu P,Chen K,Xia Y,Yu Q,Liu N,Li J,Li S,Wu L,Feng J,Wang W,Lu X,Liu T,Wang F,Dai W,Fan X,Mo W,Xu L,Guo C

Thu Nov 09 00:00:00 EST 2017

(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.

Nutrients

Chen Y,Wang XQ,Zhang Q,Zhu JY,Li Y,Xie CF,Li XT,Wu JS,Geng SS,Zhong CY,Han HY

Sat Jun 03 00:00:00 EDT 2017

(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.

Nutrients

Chen Y,Wang XQ,Zhang Q,Zhu JY,Li Y,Xie CF,Li XT,Wu JS,Geng SS,Zhong CY,Han HY

Sat Jun 03 00:00:00 EDT 2017

The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.

Scientific reports

Lu SY,Wang CY,Jin Y,Meng Q,Liu Q,Liu ZH,Liu KX,Sun HJ,Liu MZ

Tue Jun 13 00:00:00 EDT 2017

The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.

Scientific reports

Lu SY,Wang CY,Jin Y,Meng Q,Liu Q,Liu ZH,Liu KX,Sun HJ,Liu MZ

Tue Jun 13 00:00:00 EDT 2017

Sensitization of Radioresistant Prostate Cancer Cells by Resveratrol Isolated from Arachis hypogaea Stems.

PloS one

Chen YA,Lien HM,Kao MC,Lo UG,Lin LC,Lin CJ,Chang SJ,Chen CC,Hsieh JT,Lin H,Tang CH,Lai CH

Wed Aug 02 00:00:00 EDT 2017

Sensitization of Radioresistant Prostate Cancer Cells by Resveratrol Isolated from Arachis hypogaea Stems.

PloS one

Chen YA,Lien HM,Kao MC,Lo UG,Lin LC,Lin CJ,Chang SJ,Chen CC,Hsieh JT,Lin H,Tang CH,Lai CH

Wed Aug 02 00:00:00 EDT 2017

Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion.

Frontiers in physiology

Uslusoy F,Nazıroğlu M,Çiğ B

Thu Oct 01 00:00:00 EDT 2020

Frontiers in physiology

Uslusoy F,Nazıroğlu M,Çiğ B

Thu Oct 01 00:00:00 EDT 2020

ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.

Cell death & disease

Zheng Q,Li Y,Zhang D,Cui X,Dai K,Yang Y,Liu S,Tan J,Yan Q

Thu Oct 26 00:00:00 EDT 2017

ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.

Cell death & disease

Zheng Q,Li Y,Zhang D,Cui X,Dai K,Yang Y,Liu S,Tan J,Yan Q

Thu Oct 26 00:00:00 EDT 2017

Exogenous H₂S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.

Cell & bioscience

Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C

Fri Mar 11 00:00:00 EST 2022

Exogenous H₂S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.

Cell & bioscience

Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C

Fri Mar 11 00:00:00 EST 2022

Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.

Molecules (Basel, Switzerland)

Song L,Wang Z,Wang Y,Guo D,Yang J,Chen L,Tan N

Sat Nov 11 00:00:00 EST 2017

Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.

Molecules (Basel, Switzerland)

Song L,Wang Z,Wang Y,Guo D,Yang J,Chen L,Tan N

Sat Nov 11 00:00:00 EST 2017

Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy.

Frontiers in cellular and infection microbiology

Lin HJ,Liu HH,Lin CD,Kao MC,Chen YA,Chiang-Ni C,Jiang ZP,Huang MZ,Lin CJ,Lo UG,Lin LC,Lai CK,Lin H,Hsieh JT,Chiu CH,Lai CH

Fri Feb 23 00:00:00 EST 2018

Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy.

Frontiers in cellular and infection microbiology

Lin HJ,Liu HH,Lin CD,Kao MC,Chen YA,Chiang-Ni C,Jiang ZP,Huang MZ,Lin CJ,Lo UG,Lin LC,Lai CK,Lin H,Hsieh JT,Chiu CH,Lai CH

Fri Feb 23 00:00:00 EST 2018

Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.

Drug design, development and therapy

Feng J,Zhang Q,Mo W,Wu L,Li S,Li J,Liu T,Xu S,Fan X,Guo C

Thu Apr 26 00:00:00 EDT 2018

Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.

Drug design, development and therapy

Feng J,Zhang Q,Mo W,Wu L,Li S,Li J,Liu T,Xu S,Fan X,Guo C

Thu Apr 26 00:00:00 EDT 2018

Epigallocatechin-3-gallate inhibits H₂O₂-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.

Scientific reports

Yan X,Li Y,Yu H,Wang W,Wu C,Yang Y,Hu Y,Shi X,Li J

Thu Aug 10 00:00:00 EDT 2017

Epigallocatechin-3-gallate inhibits H₂O₂-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.

Scientific reports

Yan X,Li Y,Yu H,Wang W,Wu C,Yang Y,Hu Y,Shi X,Li J

Thu Aug 10 00:00:00 EDT 2017

Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zou J,Zhang Y,Sun J,Wang X,Tu H,Geng S,Liu R,Chen Y,Bi Z

Thu Nov 16 00:00:00 EST 2017

Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zou J,Zhang Y,Sun J,Wang X,Tu H,Geng S,Liu R,Chen Y,Bi Z

Thu Nov 16 00:00:00 EST 2017

Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.

Medical science monitor : international medical journal of experimental and clinical research

Zhou H,Zheng L,Lu K,Gao Y,Guo L,Xu W,Wang X

Sat Oct 07 00:00:00 EDT 2017

Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines.

Medical science monitor : international medical journal of experimental and clinical research

Zhou H,Zheng L,Lu K,Gao Y,Guo L,Xu W,Wang X

Sat Oct 07 00:00:00 EDT 2017

Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.

Scientific reports

Yüksel E,Nazıroğlu M,Şahin M,Çiğ B

Wed Dec 13 00:00:00 EST 2017

Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium.

Scientific reports

Yüksel E,Nazıroğlu M,Şahin M,Çiğ B

Wed Dec 13 00:00:00 EST 2017

Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.

Oncotarget

Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS

Tue May 09 00:00:00 EDT 2017

Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.

Oncotarget

Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS

Tue May 09 00:00:00 EDT 2017

Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.

Cancer letters

Wen C,Chen J,Zhang D,Wang H,Che J,Qin Q,He L,Cai Z,Lin M,Lou Q,Huang L,Chen D,Iwamoto A,Ren D,Wang L,Lan P,Wang J,Liu H,Yang X

Wed Dec 28 00:00:00 EST 2016

Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.

Cancer letters

Wen C,Chen J,Zhang D,Wang H,Che J,Qin Q,He L,Cai Z,Lin M,Lou Q,Huang L,Chen D,Iwamoto A,Ren D,Wang L,Lan P,Wang J,Liu H,Yang X

Wed Dec 28 00:00:00 EST 2016

Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu K,Sun H

Sun May 01 00:00:00 EDT 2016

Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu K,Sun H

Sun May 01 00:00:00 EDT 2016

Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Tang Q,Ji F,Guo J,Wang J,Li Y,Bao Y

Mon Aug 01 00:00:00 EDT 2016

Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Tang Q,Ji F,Guo J,Wang J,Li Y,Bao Y

Mon Aug 01 00:00:00 EDT 2016

Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y

Thu Dec 15 00:00:00 EST 2016

Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y

Thu Dec 15 00:00:00 EST 2016

Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhao L,Wen Q,Yang G,Huang Z,Shen T,Li H,Ren D

Mon Feb 15 00:00:00 EST 2016

Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhao L,Wen Q,Yang G,Huang Z,Shen T,Li H,Ren D

Mon Feb 15 00:00:00 EST 2016

Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.

Environmental toxicology and pharmacology

Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J

Fri Jul 01 00:00:00 EDT 2016

Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.

Environmental toxicology and pharmacology

Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J

Fri Jul 01 00:00:00 EDT 2016

Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.

Environmental toxicology and pharmacology

Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J

Fri Jul 01 00:00:00 EDT 2016

Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway.

Environmental toxicology and pharmacology

Wang C,Li T,Tang S,Zhao D,Zhang C,Zhang S,Deng S,Zhou Y,Xiao X

Fri Jan 01 00:00:00 EST 2016

Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway.

Environmental toxicology and pharmacology

Wang C,Li T,Tang S,Zhao D,Zhang C,Zhang S,Deng S,Zhou Y,Xiao X

Fri Jan 01 00:00:00 EST 2016

Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.

International immunopharmacology

Sun B,Gao L,Ahsan A,Chu P,Song Y,Li H,Zhang Z,Lin Y,Peng J,Song Z,Wang S,Tang Z

Tue Nov 01 00:00:00 EDT 2016

Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.

International immunopharmacology

Sun B,Gao L,Ahsan A,Chu P,Song Y,Li H,Zhang Z,Lin Y,Peng J,Song Z,Wang S,Tang Z

Tue Nov 01 00:00:00 EDT 2016

Phosphocreatine protects against LPS-induced human umbilical vein endothelial cell apoptosis by regulating mitochondrial oxidative phosphorylation.

Apoptosis : an international journal on programmed cell death

Sun Z,Lan X,Ahsan A,Xi Y,Liu S,Zhang Z,Chu P,Song Y,Piao F,Peng J,Lin Y,Han G,Tang Z

Tue Mar 01 00:00:00 EST 2016

Phosphocreatine protects against LPS-induced human umbilical vein endothelial cell apoptosis by regulating mitochondrial oxidative phosphorylation.

Apoptosis : an international journal on programmed cell death

Sun Z,Lan X,Ahsan A,Xi Y,Liu S,Zhang Z,Chu P,Song Y,Piao F,Peng J,Lin Y,Han G,Tang Z

Tue Mar 01 00:00:00 EST 2016

Anti-tumor effects of osthole on ovarian cancer cells in vitro.

Journal of ethnopharmacology

Jiang G,Liu J,Ren B,Tang Y,Owusu L,Li M,Zhang J,Liu L,Li W

Sun Dec 04 00:00:00 EST 2016

Anti-tumor effects of osthole on ovarian cancer cells in vitro.

Journal of ethnopharmacology

Jiang G,Liu J,Ren B,Tang Y,Owusu L,Li M,Zhang J,Liu L,Li W

Sun Dec 04 00:00:00 EST 2016

Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.

European journal of pharmacology

Si L,Zheng L,Xu L,Yin L,Han X,Qi Y,Xu Y,Wang C,Peng J

Sat Mar 05 00:00:00 EST 2016

Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.

European journal of pharmacology

Si L,Zheng L,Xu L,Yin L,Han X,Qi Y,Xu Y,Wang C,Peng J

Sat Mar 05 00:00:00 EST 2016

Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.

Cell cycle (Georgetown, Tex.)

Yuan S,Wen J,Cheng J,Shen W,Zhou S,Yan W,Shen L,Luo A,Wang S

Tue Nov 01 00:00:00 EDT 2016

Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.

Cell cycle (Georgetown, Tex.)

Yuan S,Wen J,Cheng J,Shen W,Zhou S,Yan W,Shen L,Luo A,Wang S

Tue Nov 01 00:00:00 EDT 2016

SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.

Chemico-biological interactions

Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z

Mon Jan 25 00:00:00 EST 2016

SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.

Chemico-biological interactions

Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z

Mon Jan 25 00:00:00 EST 2016

Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.

Molecular carcinogenesis

Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H

Sun May 01 00:00:00 EDT 2016

Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.

Molecular carcinogenesis

Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H

Sun May 01 00:00:00 EDT 2016

HIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.

Cancer biology & therapy

Zhe N,Chen S,Zhou Z,Liu P,Lin X,Yu M,Cheng B,Zhang Y,Wang J

Thu Jun 02 00:00:00 EDT 2016

HIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.

Cancer biology & therapy

Zhe N,Chen S,Zhou Z,Liu P,Lin X,Yu M,Cheng B,Zhang Y,Wang J

Thu Jun 02 00:00:00 EDT 2016

Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.

Journal of cellular biochemistry

Wang L,Wang C,Jia Y,Liu Z,Shu X,Liu K

Sun May 01 00:00:00 EDT 2016

Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.

Journal of cellular biochemistry

Wang L,Wang C,Jia Y,Liu Z,Shu X,Liu K

Sun May 01 00:00:00 EDT 2016

CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.

Experimental and molecular pathology

Xia ZX,Li ZX,Zhang M,Sun LM,Zhang QF,Qiu XS

Fri Apr 01 00:00:00 EDT 2016

CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway.

Experimental and molecular pathology

Xia ZX,Li ZX,Zhang M,Sun LM,Zhang QF,Qiu XS

Fri Apr 01 00:00:00 EDT 2016

Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.

Oncology reports

Zhao Y,Jing Z,Li Y,Mao W

Fri Jul 01 00:00:00 EDT 2016

Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis.

Oncology reports

Zhao Y,Jing Z,Li Y,Mao W

Fri Jul 01 00:00:00 EDT 2016

Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.

Oncology reports

Gao L,Xu Z,Wang Y,Sun B,Song Z,Yang B,Liu X,Lin Y,Peng J,Han G,Wang S,Tang Z

Mon Feb 01 00:00:00 EST 2016

Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.

Oncology reports

Gao L,Xu Z,Wang Y,Sun B,Song Z,Yang B,Liu X,Lin Y,Peng J,Han G,Wang S,Tang Z

Mon Feb 01 00:00:00 EST 2016

ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line.

Toxicology mechanisms and methods

Zhou Y,Zhang S,Deng S,Dai C,Tang S,Yang X,Li D,Zhao K,Xiao X

Wed Dec 14 00:00:00 EST 2016

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Inhibition of Human Glioma Cell Proliferation Caused by Knockdown of Utrophin Using a Lentivirus-Mediated System.

Cancer biotherapy & radiopharmaceuticals

Shen SH,Yu N,Xu H,Liu XY,Tan GW,Wang ZX

Sun May 01 00:00:00 EDT 2016

Inhibition of Human Glioma Cell Proliferation Caused by Knockdown of Utrophin Using a Lentivirus-Mediated System.

Cancer biotherapy & radiopharmaceuticals

Shen SH,Yu N,Xu H,Liu XY,Tan GW,Wang ZX

Sun May 01 00:00:00 EDT 2016

Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.

Radiation research

Xu Y,Wu D,Fan Y,Li P,Du H,Shi J,Wang D,Zhou X

Fri Jan 01 00:00:00 EST 2016

Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.

Radiation research

Xu Y,Wu D,Fan Y,Li P,Du H,Shi J,Wang D,Zhou X

Fri Jan 01 00:00:00 EST 2016

Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.

Fitoterapia

Lu YZ,Li PF,Li YZ,Luo F,Guo C,Lin B,Cao XW,Zhao J,Wang FJ

Fri Jul 01 00:00:00 EDT 2016

Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.

Fitoterapia

Lu YZ,Li PF,Li YZ,Luo F,Guo C,Lin B,Cao XW,Zhao J,Wang FJ

Fri Jul 01 00:00:00 EDT 2016

Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway.

Neuroscience letters

Tang D,Wang C,Gao Y,Pu J,Long J,Xu W

Thu Oct 06 00:00:00 EDT 2016

Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway.

Neuroscience letters

Tang D,Wang C,Gao Y,Pu J,Long J,Xu W

Thu Oct 06 00:00:00 EDT 2016

BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.

Theriogenology

Lei X,Cui K,Li Z,Su J,Jiang J,Zhang H,Liu Q,Shi D

Tue Mar 15 00:00:00 EDT 2016

BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.

Theriogenology

Lei X,Cui K,Li Z,Su J,Jiang J,Zhang H,Liu Q,Shi D

Tue Mar 15 00:00:00 EDT 2016

Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells.

Biotechnology letters

Zhao C,Su G,Wang X,Zhang X,Guo S,Zhao Y

Fri Jan 01 00:00:00 EST 2016

Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells.

Biotechnology letters

Zhao C,Su G,Wang X,Zhang X,Guo S,Zhao Y

Fri Jan 01 00:00:00 EST 2016

KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X

Mon Feb 15 00:00:00 EST 2016

Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes.

Cell & bioscience

Li L,Li M,Li Y,Sun W,Wang Y,Bai S,Li H,Wu B,Yang G,Wang R,Wu L,Li H,Xu C

Wed Apr 20 00:00:00 EDT 2016

Cell & bioscience

Li L,Li M,Li Y,Sun W,Wang Y,Bai S,Li H,Wu B,Yang G,Wang R,Wu L,Li H,Xu C

Wed Apr 20 00:00:00 EDT 2016

Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Peng X,Zhang YY,Wang J,Ji Q

Fri Jan 01 00:00:00 EST 2016

Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Peng X,Zhang YY,Wang J,Ji Q

Fri Jan 01 00:00:00 EST 2016

The neuroprotective action of dexmedetomidine on apoptosis, calcium entry and oxidative stress in cerebral ischemia-induced rats: Contribution of TRPM2 and TRPV1 channels.

Scientific reports

Akpınar H,Nazıroğlu M,Övey İS,Çiğ B,Akpınar O

Tue Nov 22 00:00:00 EST 2016

The neuroprotective action of dexmedetomidine on apoptosis, calcium entry and oxidative stress in cerebral ischemia-induced rats: Contribution of TRPM2 and TRPV1 channels.

Scientific reports

Akpınar H,Nazıroğlu M,Övey İS,Çiğ B,Akpınar O

Tue Nov 22 00:00:00 EST 2016

Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway.

BMC microbiology

Li Y,Jiang Z,Xue D,Deng G,Li M,Liu X,Wang Y

Fri Sep 23 00:00:00 EDT 2016

Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway.

BMC microbiology

Li Y,Jiang Z,Xue D,Deng G,Li M,Liu X,Wang Y

Fri Sep 23 00:00:00 EDT 2016

Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Ju D,Yamaguchi F,Zhan G,Higuchi T,Asakura T,Morita A,Orimo H,Hu S

Mon Aug 01 00:00:00 EDT 2016

Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Ju D,Yamaguchi F,Zhan G,Higuchi T,Asakura T,Morita A,Orimo H,Hu S

Mon Aug 01 00:00:00 EDT 2016

DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.

Scientific reports

Zou M,Duan Y,Wang P,Gao R,Chen X,Ou Y,Liang M,Wang Z,Yuan Y,Wang L,Zhu H

Thu Jun 02 00:00:00 EDT 2016

DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.

Scientific reports

Zou M,Duan Y,Wang P,Gao R,Chen X,Ou Y,Liang M,Wang Z,Yuan Y,Wang L,Zhu H

Thu Jun 02 00:00:00 EDT 2016

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.

PloS one

Li J,Chen K,Li S,Liu T,Wang F,Xia Y,Lu J,Zhou Y,Guo C

Mon Aug 15 00:00:00 EDT 2016

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.

PloS one

Li J,Chen K,Li S,Liu T,Wang F,Xia Y,Lu J,Zhou Y,Guo C

Mon Aug 15 00:00:00 EDT 2016

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.

PloS one

Li J,Chen K,Li S,Liu T,Wang F,Xia Y,Lu J,Zhou Y,Guo C

Mon Aug 15 00:00:00 EDT 2016

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.

PloS one

Li J,Chen K,Li S,Liu T,Wang F,Xia Y,Lu J,Zhou Y,Guo C

Mon Aug 15 00:00:00 EDT 2016

Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.

Molecular membrane biology

Öz A,Çelik Ö

Wed Nov 20 00:00:00 EST 2019

Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.

Molecular membrane biology

Öz A,Çelik Ö

Wed Nov 20 00:00:00 EST 2019

Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.

Molecules (Basel, Switzerland)

Zhao X,Tao X,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J

Sat Jun 04 00:00:00 EDT 2016

Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.

Molecules (Basel, Switzerland)

Zhao X,Tao X,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J

Sat Jun 04 00:00:00 EDT 2016

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway.

Oncotarget

Chen X,Wang L,Zhao Y,Yuan S,Wu Q,Zhu X,Niang B,Wang S,Zhang J

Tue Aug 09 00:00:00 EDT 2016

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway.

Oncotarget

Chen X,Wang L,Zhao Y,Yuan S,Wu Q,Zhu X,Niang B,Wang S,Zhang J

Tue Aug 09 00:00:00 EDT 2016

Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice.

Journal of nanobiotechnology

Wang X,Tian J,Yong KT,Zhu X,Lin MC,Jiang W,Li J,Huang Q,Lin G

Thu Feb 04 00:00:00 EST 2016

Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice.

Journal of nanobiotechnology

Wang X,Tian J,Yong KT,Zhu X,Lin MC,Jiang W,Li J,Huang Q,Lin G

Thu Feb 04 00:00:00 EST 2016

Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.

Frontiers in cellular and infection microbiology

Cui Y,Zhao D,Sreevatsan S,Liu C,Yang W,Song Z,Yang L,Barrow P,Zhou X

Thu Sep 21 00:00:00 EDT 2017

Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.

Frontiers in cellular and infection microbiology

Cui Y,Zhao D,Sreevatsan S,Liu C,Yang W,Song Z,Yang L,Barrow P,Zhou X

Thu Sep 21 00:00:00 EDT 2017

IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.

Cancer letters

Yuan L,Zhou C,Lu Y,Hong M,Zhang Z,Zhang Z,Chang Y,Zhang C,Li X

Wed Apr 01 00:00:00 EDT 2015

IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.

Cancer letters

Yuan L,Zhou C,Lu Y,Hong M,Zhang Z,Zhang Z,Chang Y,Zhang C,Li X

Wed Apr 01 00:00:00 EDT 2015

Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro.

Biological research

Pan Z,Pan H,Zhang J,Yang Y,Liu H,Yang Y,Huang G,Ni J,Huang J,Zhou W

Thu Mar 19 00:00:00 EDT 2015

Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro.

Biological research

Pan Z,Pan H,Zhang J,Yang Y,Liu H,Yang Y,Huang G,Ni J,Huang J,Zhou W

Thu Mar 19 00:00:00 EDT 2015

Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.

Journal of cellular physiology

Fu C,Xu D,Wang CY,Jin Y,Liu Q,Meng Q,Liu KX,Sun HJ,Liu MZ

Tue Sep 01 00:00:00 EDT 2015

Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.

Journal of cellular physiology

Fu C,Xu D,Wang CY,Jin Y,Liu Q,Meng Q,Liu KX,Sun HJ,Liu MZ

Tue Sep 01 00:00:00 EDT 2015

Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis.

Phytotherapy research : PTR

Guo LD,Shen YQ,Zhao XH,Guo LJ,Yu ZJ,Wang D,Liu LM,Liu JZ

Sun Mar 01 00:00:00 EST 2015

Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis.

Phytotherapy research : PTR

Guo LD,Shen YQ,Zhao XH,Guo LJ,Yu ZJ,Wang D,Liu LM,Liu JZ

Sun Mar 01 00:00:00 EST 2015

Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.

International journal of oncology

Li X,Liu X,Xu Y,He Y,Liu J,Xie M

Sun Feb 01 00:00:00 EST 2015

Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins.

International journal of oncology

Li X,Liu X,Xu Y,He Y,Liu J,Xie M

Sun Feb 01 00:00:00 EST 2015

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International journal of oncology

Shan X,Tian LL,Zhang YM,Wang XQ,Yan Q,Liu JW

Sat Aug 01 00:00:00 EDT 2015

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International journal of oncology

Shan X,Tian LL,Zhang YM,Wang XQ,Yan Q,Liu JW

Sat Aug 01 00:00:00 EDT 2015

Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells.

International journal of oncology

Wen C,Huang L,Chen J,Lin M,Li W,Lu B,Rutnam ZJ,Iwamoto A,Wang Z,Yang X,Liu H

Sun Nov 01 00:00:00 EDT 2015

Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells.

International journal of oncology

Wen C,Huang L,Chen J,Lin M,Li W,Lu B,Rutnam ZJ,Iwamoto A,Wang Z,Yang X,Liu H

Sun Nov 01 00:00:00 EDT 2015

Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.

International immunopharmacology

Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y

Tue Dec 01 00:00:00 EST 2015

Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.

International immunopharmacology

Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y

Tue Dec 01 00:00:00 EST 2015

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Deng S,Tang S,Zhang S,Zhang C,Wang C,Zhou Y,Dai C,Xiao X

Thu Jan 01 00:00:00 EST 2015

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Deng S,Tang S,Zhang S,Zhang C,Wang C,Zhou Y,Dai C,Xiao X

Thu Jan 01 00:00:00 EST 2015

Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.

Apoptosis : an international journal on programmed cell death

Ahsan A,Han G,Pan J,Liu S,Padhiar AA,Chu P,Sun Z,Zhang Z,Sun B,Wu J,Irshad A,Lin Y,Peng J,Tang Z

Tue Dec 01 00:00:00 EST 2015

Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.

Apoptosis : an international journal on programmed cell death

Ahsan A,Han G,Pan J,Liu S,Padhiar AA,Chu P,Sun Z,Zhang Z,Sun B,Wu J,Irshad A,Lin Y,Peng J,Tang Z

Tue Dec 01 00:00:00 EST 2015

SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.

Apoptosis : an international journal on programmed cell death

Gao L,Wang Y,Xu Z,Li X,Wu J,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z

Tue Dec 01 00:00:00 EST 2015

SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.

Apoptosis : an international journal on programmed cell death

Gao L,Wang Y,Xu Z,Li X,Wu J,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z

Tue Dec 01 00:00:00 EST 2015

O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.

Chemico-biological interactions

Liao H,Bao X,Zhu J,Qu J,Sun Y,Ma X,Wang E,Guo X,Kang Q,Zhen Y

Sat Dec 05 00:00:00 EST 2015

O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.

Chemico-biological interactions

Liao H,Bao X,Zhu J,Qu J,Sun Y,Ma X,Wang E,Guo X,Kang Q,Zhen Y

Sat Dec 05 00:00:00 EST 2015

Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.

OncoTargets and therapy

Chen K,Dai W,Wang F,Xia Y,Li J,Li S,Liu T,Zhang R,Wang J,Lu W,Zhou Y,Yin Q,Zheng Y,Abudumijiti H,Chen R,Lu J,Zhou Y,Guo C

Tue Dec 15 00:00:00 EST 2015

Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.

OncoTargets and therapy

Chen K,Dai W,Wang F,Xia Y,Li J,Li S,Liu T,Zhang R,Wang J,Lu W,Zhou Y,Yin Q,Zheng Y,Abudumijiti H,Chen R,Lu J,Zhou Y,Guo C

Tue Dec 15 00:00:00 EST 2015

Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.

Experimental gerontology

Wang W,Sun Y,Chen S,Zhou X,Wu X,Kong W,Kong W

Thu Oct 01 00:00:00 EDT 2015

Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.

Experimental gerontology

Wang W,Sun Y,Chen S,Zhou X,Wu X,Kong W,Kong W

Thu Oct 01 00:00:00 EDT 2015

Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.

Experimental gerontology

Wang W,Sun Y,Chen S,Zhou X,Wu X,Kong W,Kong W

Thu Oct 01 00:00:00 EDT 2015

Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.

Experimental gerontology

Wang W,Sun Y,Chen S,Zhou X,Wu X,Kong W,Kong W

Thu Oct 01 00:00:00 EDT 2015

Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway.

Oncology reports

Tong X,Han X,Yu B,Yu M,Jiang G,Ji J,Dong S

Thu Jan 01 00:00:00 EST 2015

Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway.

Oncology reports

Tong X,Han X,Yu B,Yu M,Jiang G,Ji J,Dong S

Thu Jan 01 00:00:00 EST 2015

DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.

Medical oncology (Northwood, London, England)

Huang W,Liu J,Feng X,Chen H,Zeng L,Huang G,Liu W,Wang L,Jia W,Chen J,Ren C

Wed Apr 01 00:00:00 EDT 2015

DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.

Medical oncology (Northwood, London, England)

Huang W,Liu J,Feng X,Chen H,Zeng L,Huang G,Liu W,Wang L,Jia W,Chen J,Ren C

Wed Apr 01 00:00:00 EDT 2015

Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.

Brain research

Zhang HT,Xue JH,Zhang ZW,Kong HB,Liu AJ,Li SC,Xu DG

Mon Oct 05 00:00:00 EDT 2015

Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.

Brain research

Zhang HT,Xue JH,Zhang ZW,Kong HB,Liu AJ,Li SC,Xu DG

Mon Oct 05 00:00:00 EDT 2015

Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.

Biochemical and biophysical research communications

Wu P,Zhu X,Jin W,Hao S,Liu Q,Zhang L

Fri May 01 00:00:00 EDT 2015

Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.

Biochemical and biophysical research communications

Wu P,Zhu X,Jin W,Hao S,Liu Q,Zhang L

Fri May 01 00:00:00 EDT 2015

TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis.

BMC cancer

Yuan MM,Xu YY,Chen L,Li XY,Qin J,Shen Y

Thu Apr 09 00:00:00 EDT 2015

TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis.

BMC cancer

Yuan MM,Xu YY,Chen L,Li XY,Qin J,Shen Y

Thu Apr 09 00:00:00 EDT 2015

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy.

Oncotarget

Qin CJ,Song XM,Chen ZH,Ren XQ,Xu KW,Jing H,He YL

Tue Oct 13 00:00:00 EDT 2015

MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Yang T,Thakur A,Chen T,Yang L,Lei G,Liang Y,Zhang S,Ren H,Chen M

Mon Jun 01 00:00:00 EDT 2015

MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Yang T,Thakur A,Chen T,Yang L,Lei G,Liang Y,Zhang S,Ren H,Chen M

Mon Jun 01 00:00:00 EDT 2015

Potent effects of dioscin against liver fibrosis.

Scientific reports

Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J

Wed Apr 08 00:00:00 EDT 2015

Potent effects of dioscin against liver fibrosis.

Scientific reports

Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J

Wed Apr 08 00:00:00 EDT 2015

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.

Drug design, development and therapy

Mao Y,Wang J,Yu F,Cheng J,Li H,Guo C,Fan X

Wed Jul 06 00:00:00 EDT 2016

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.

Drug design, development and therapy

Mao Y,Wang J,Yu F,Cheng J,Li H,Guo C,Fan X

Wed Jul 06 00:00:00 EDT 2016

Protective effects of dioscin against alcohol-induced liver injury.

Archives of toxicology

Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J

Sat Mar 01 00:00:00 EST 2014

Protective effects of dioscin against alcohol-induced liver injury.

Archives of toxicology

Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J

Sat Mar 01 00:00:00 EST 2014

Protective effects of dioscin against alcohol-induced liver injury.

Archives of toxicology

Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J

Sat Mar 01 00:00:00 EST 2014

Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.

International immunopharmacology

Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J

Tue Apr 01 00:00:00 EDT 2014

Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.

International immunopharmacology

Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J

Tue Apr 01 00:00:00 EDT 2014

Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.

International immunopharmacology

Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y

Wed Oct 01 00:00:00 EDT 2014

Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.

International immunopharmacology

Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y

Wed Oct 01 00:00:00 EDT 2014

Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

Toxicology and applied pharmacology

Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y

Wed Oct 15 00:00:00 EDT 2014

Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

Toxicology and applied pharmacology

Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y

Wed Oct 15 00:00:00 EDT 2014

Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.

Oncology reports

Sun Q,Wang R,Wang Y,Luo J,Wang P,Cheng B

Sat Feb 01 00:00:00 EST 2014

Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.

Oncology reports

Sun Q,Wang R,Wang Y,Luo J,Wang P,Cheng B

Sat Feb 01 00:00:00 EST 2014

Inhibition of autophagy promotes caspase-mediated apoptosis by tunicamycin in HepG2 cells.

Toxicology mechanisms and methods

Zhang S,Wang C,Tang S,Deng S,Zhou Y,Dai C,Yang X,Xiao X

Mon Dec 01 00:00:00 EST 2014

Inhibition of autophagy promotes caspase-mediated apoptosis by tunicamycin in HepG2 cells.

Toxicology mechanisms and methods

Zhang S,Wang C,Tang S,Deng S,Zhou Y,Dai C,Yang X,Xiao X

Mon Dec 01 00:00:00 EST 2014

Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Wu J,Chen W,Yin Y,Zheng Z,Zou G

Sun Jun 01 00:00:00 EDT 2014

Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Wu J,Chen W,Yin Y,Zheng Z,Zou G

Sun Jun 01 00:00:00 EDT 2014

Apoptosis Induction by the Total Flavonoids from Arachniodes exilis in HepG2 Cells through Reactive Oxygen Species-Mediated Mitochondrial Dysfunction Involving MAPK Activation.

Evidence-based complementary and alternative medicine : eCAM

Li H,Chen J,Xiong C,Wei H,Yin C,Ruan J

Mon Jun 30 00:00:00 EDT 2014

Apoptosis Induction by the Total Flavonoids from Arachniodes exilis in HepG2 Cells through Reactive Oxygen Species-Mediated Mitochondrial Dysfunction Involving MAPK Activation.

Evidence-based complementary and alternative medicine : eCAM

Li H,Chen J,Xiong C,Wei H,Yin C,Ruan J

Mon Jun 30 00:00:00 EDT 2014

Total flavonoids of litsea coreana enhance the cytotoxicity of oxaliplatin by increasing gap junction intercellular communication.

Biological & pharmaceutical bulletin

Yu BB,Dong SY,Yu ML,Jiang GJ,Ji J,Tong XH

Mon Apr 06 00:00:00 EDT 2015

Total flavonoids of litsea coreana enhance the cytotoxicity of oxaliplatin by increasing gap junction intercellular communication.

Biological & pharmaceutical bulletin

Yu BB,Dong SY,Yu ML,Jiang GJ,Ji J,Tong XH

Mon Apr 06 00:00:00 EDT 2015

Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.

Current pharmaceutical biotechnology

Li W,Wang C,Peng J,Liang J,Jin Y,Liu Q,Meng Q,Liu K,Sun H

Mon Aug 31 00:00:00 EDT 2015

Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.

Molecules (Basel, Switzerland)

Dong D,Xu L,Han X,Qi Y,Xu Y,Yin L,Liu K,Peng J

Fri May 30 00:00:00 EDT 2014

Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice.

PloS one

Wang T,Li Y,Wang Y,Zhou R,Ma L,Hao Y,Jin S,Du J,Zhao C,Sun T,Yu J

Tue Nov 04 00:00:00 EST 2014

Lycium barbarum polysaccharide prevents focal cerebral ischemic injury by inhibiting neuronal apoptosis in mice.

PloS one

Wang T,Li Y,Wang Y,Zhou R,Ma L,Hao Y,Jin S,Du J,Zhao C,Sun T,Yu J

Tue Nov 04 00:00:00 EST 2014

The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice.

Cell death & disease

An J,Zhang X,Qin J,Wan Y,Hu Y,Liu T,Li J,Dong W,Du E,Pan C,Zeng W

Thu Apr 24 00:00:00 EDT 2014

The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice.

Cell death & disease

An J,Zhang X,Qin J,Wan Y,Hu Y,Liu T,Li J,Dong W,Du E,Pan C,Zeng W

Thu Apr 24 00:00:00 EDT 2014

Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.

Molecules (Basel, Switzerland)

Liu M,Xu Y,Han X,Liang C,Yin L,Xu L,Qi Y,Zhao Y,Peng J,Sun C

Thu Aug 07 00:00:00 EDT 2014

Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.

Molecules (Basel, Switzerland)

Liu M,Xu Y,Han X,Liang C,Yin L,Xu L,Qi Y,Zhao Y,Peng J,Sun C

Thu Aug 07 00:00:00 EDT 2014

Emodin regulates apoptotic pathway in human liver cancer cells.

Phytotherapy research : PTR

Yu JQ,Bao W,Lei JC

Fri Feb 01 00:00:00 EST 2013

Emodin regulates apoptotic pathway in human liver cancer cells.

Phytotherapy research : PTR

Yu JQ,Bao W,Lei JC

Fri Feb 01 00:00:00 EST 2013

Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene therapy induces both extrinsic and intrinsic apoptosis in a rat model of bladder cancer.

Cancer gene therapy

Yin X,Yu B,Tang Z,He B,Ren J,Xiao X,Tang W

Fri Feb 01 00:00:00 EST 2013

Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene therapy induces both extrinsic and intrinsic apoptosis in a rat model of bladder cancer.

Cancer gene therapy

Yin X,Yu B,Tang Z,He B,Ren J,Xiao X,Tang W

Fri Feb 01 00:00:00 EST 2013

TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Zhang C,Wang C,Tang S,Sun Y,Zhao D,Zhang S,Deng S,Zhou Y,Xiao X

Sun Dec 01 00:00:00 EST 2013

TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Zhang C,Wang C,Tang S,Sun Y,Zhao D,Zhang S,Deng S,Zhou Y,Xiao X

Sun Dec 01 00:00:00 EST 2013

Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Dong D,Zhang S,Yin L,Tang X,Xu Y,Han X,Qi Y,Peng J

Sun Dec 01 00:00:00 EST 2013

Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Dong D,Zhang S,Yin L,Tang X,Xu Y,Han X,Qi Y,Peng J

Sun Dec 01 00:00:00 EST 2013

Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation.

International journal of molecular medicine

Abid MD,Chen J,Xiang M,Zhou J,Chen X,Gong F

Thu Aug 01 00:00:00 EDT 2013

Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation.

International journal of molecular medicine

Abid MD,Chen J,Xiang M,Zhou J,Chen X,Gong F

Thu Aug 01 00:00:00 EDT 2013

The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as cardiovascular-protective agents.

European journal of medicinal chemistry

Jia Y,Dong X,Zhou P,Liu X,Pan L,Xin H,Zhu YZ,Wang Y

Sat Sep 01 00:00:00 EDT 2012

The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as cardiovascular-protective agents.

European journal of medicinal chemistry

Jia Y,Dong X,Zhou P,Liu X,Pan L,Xin H,Zhu YZ,Wang Y

Sat Sep 01 00:00:00 EDT 2012

Alantolactone induces activation of apoptosis in human hepatoma cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Lei JC,Yu JQ,Yin Y,Liu YW,Zou GL

Sat Sep 01 00:00:00 EDT 2012

Alantolactone induces activation of apoptosis in human hepatoma cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Lei JC,Yu JQ,Yin Y,Liu YW,Zou GL

Sat Sep 01 00:00:00 EDT 2012

Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.

International journal of molecular medicine

Yi S,Chen Y,Wen L,Yang L,Cui G

Mon Oct 01 00:00:00 EDT 2012

Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.

International journal of molecular medicine

Yi S,Chen Y,Wen L,Yang L,Cui G

Mon Oct 01 00:00:00 EDT 2012

NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G

Thu Dec 01 00:00:00 EST 2011

NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G

Thu Dec 01 00:00:00 EST 2011

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.

European journal of pharmacology

Liu H,Xiao Y,Xiong C,Wei A,Ruan J

Fri Mar 11 00:00:00 EST 2011

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.

European journal of pharmacology

Liu H,Xiao Y,Xiong C,Wei A,Ruan J

Fri Mar 11 00:00:00 EST 2011

Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.

PloS one

Zheng S,Chang S,Lu J,Chen Z,Xie L,Nie Y,He B,Zou S,Gu Z

Fri Oct 21 00:00:00 EDT 2011

Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.

PloS one

Zheng S,Chang S,Lu J,Chen Z,Xie L,Nie Y,He B,Zou S,Gu Z

Fri Oct 21 00:00:00 EDT 2011

alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

Biochemical pharmacology

Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G

Thu Jul 15 00:00:00 EDT 2010

alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

Biochemical pharmacology

Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G

Thu Jul 15 00:00:00 EDT 2010

Adaptor FADD is recruited by RTN3/HAP in ER-bound signaling complexes.

Apoptosis : an international journal on programmed cell death

Xiang R,Liu Y,Zhu L,Dong W,Qi Y

Wed Nov 01 00:00:00 EST 2006

Adaptor FADD is recruited by RTN3/HAP in ER-bound signaling complexes.

Apoptosis : an international journal on programmed cell death

Xiang R,Liu Y,Zhu L,Dong W,Qi Y

Wed Nov 01 00:00:00 EST 2006

Bioinformatics

Protein Aliases: 25 kDa caspase-9 dominant negative protein; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; caspase 9, apoptosis-related cysteine peptidase; Caspase-9; caspase-9 dominant negative form; caspase-9-carboxyl-terminal divergent; ICE-LAP6; ICE-like apoptotic protease 6; protein phosphatase 1, regulatory subunit 56

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Gene Aliases: AI115399; APAF-3; APAF3; AW493809; CASP-9; Casp-9-CTD; CASP9; Casp9_v1; Caspase-9; ICE-LAP6; MCH6; PPP1R56

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UniProt ID: (Human) P55211, (Mouse) Q8C3Q9

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Entrez Gene ID: (Human) 842, (Mouse) 12371, (Rat) 58918

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Function(s)

cysteine-type endopeptidase activity protein binding enzyme activator activity peptidase activity SH3 domain binding protein kinase binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type peptidase activity hydrolase activity cysteine-type endopeptidase activity involved in apoptotic signaling pathway protease

Process(es)

proteolysis apoptotic process cellular response to DNA damage stimulus aging intrinsic apoptotic signaling pathway in response to DNA damage activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c platelet formation response to cobalt ion response to estradiol response to lipopolysaccharide glial cell apoptotic process cellular response to UV signal transduction in response to DNA damage positive regulation of neuron apoptotic process response to antibiotic cellular response to dexamethasone stimulus extrinsic apoptotic signaling pathway in absence of ligand regulation of response to DNA damage stimulus activation of cysteine-type endopeptidase activity involved in apoptotic process response to UV response to organic cyclic compound regulation of apoptotic process positive regulation of apoptotic process cellular response to organic cyclic compound

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Caspase 9/p35/p10 Polyclonal Antibody

Caspase 9/p35/p10 Antibody (10380-1-AP) in ICC/IF

Product Details

10380-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Immunoprecipitation (IP)

RNA Immunoprecipitation (RIP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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