Product References
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
European journal of medicinal chemistry
Lin H,Han H,Yang M,Wen Z,Chen Q,Ma Y,Wang X,Wang C,Yin T,Wang X,Lu G,Chen H,Qi J,Yang Y
Sun Mar 05 00:00:00 EST 2023
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
European journal of pharmacology
Ding JF,Zhou Y,Xu SS,Shi KH,Sun H,Tu B,Song K,Xuan HY,Sha JM,Zhao JY,Tao H
Thu Jan 05 00:00:00 EST 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Modulation of the Microbiome-Fat-Liver Axis by Lactic Acid Bacteria: A Potential Alleviated Role in High-Fat-Diet-Induced Obese Mice.
Journal of agricultural and food chemistry
Wei B,Peng Z,Xiao M,Huang T,Yang S,Liu K,Wu M,Zheng W,Xie M,Xiong T
Wed Jul 12 00:00:00 EDT 2023
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Food & function
Wu Y,Duan Z,Qu L,Zhang Y,Zhu C,Fan D
Tue Jun 06 00:00:00 EDT 2023
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Song D,Zhang A,Hu X,Zeng M,Zhou H
Tue Jul 25 00:00:00 EDT 2023
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Song D,Zhang A,Hu X,Zeng M,Zhou H
Tue Jul 25 00:00:00 EDT 2023
Dual role of NR4A1 in porcine ovarian granulosa cell differentiation and granulosa-lutein cell regression in vitro.
Theriogenology
Yu H,Zhao J,Pei X,Xia Y,Li H,Wang W,Mao D
Wed Mar 01 00:00:00 EST 2023
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Free radical biology & medicine
Yao JM,Ying HZ,Zhang HH,Qiu FS,Wu JQ,Yu CH
Wed Feb 01 00:00:00 EST 2023
Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang L,Li L,Chen X,Yuan S,Xu T,Zhao W,Li M,Wang F,Hoffman RM,Jia L
Sun Jan 01 00:00:00 EST 2023
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Li W,Bian Y,Jiang X,Zhu F,Yin F,Yin L,Song X,Guo H,Liu J
Sat Apr 01 00:00:00 EDT 2023
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Kidney & blood pressure research
Gu W,Yang L,Wang X,Geng J,Li X,Zheng K,Guan Y,Hou X,Wang C,Song G
Mon Aug 15 00:00:00 EDT 2022
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
Journal of translational medicine
Lin K,Shen SH,Lu F,Zheng P,Wu S,Liao J,Jiang X,Zeng G,Wei D
Sat Feb 19 00:00:00 EST 2022
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
In vitro cellular & developmental biology. Animal
Yang M,Feng J,Lan X,Tang Y,Zhang Y,Zhang H,Wang S
Tue Mar 01 00:00:00 EST 2022
Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission.
Journal of natural products
Chen XJ,Cui QX,Wang GL,Li XL,Zhou XL,Zhao HJ,Zhang MQ,Li MJ,He XJ,Zheng QS,Wang YL,Li D,Hong P
Fri Oct 28 00:00:00 EDT 2022
Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.
Journal of immunology research
Jin X,Dai G,Xuan L,Zhang M,Jiang H,Sui Y
Tue Apr 19 00:00:00 EDT 2022
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells.
Cellular immunology
Wu YN,Zhang R,Song XC,Han XX,Zhang J,Li X
Sat Jan 01 00:00:00 EST 2022
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells.
Cellular immunology
Wu YN,Zhang R,Song XC,Han XX,Zhang J,Li X
Sat Jan 01 00:00:00 EST 2022
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Life sciences
Chen Q,Han H,Lin F,Yang L,Feng L,Lai X,Wen Z,Yang M,Wang C,Ma Y,Yin T,Lu G,Lin H,Qi J,Yang Y
Thu Dec 01 00:00:00 EST 2022
Self-Assembling Imageable Silk Hydrogels for the Focal Treatment of Osteosarcoma.
Frontiers in cell and developmental biology
Peng Z,Li M,Wang Y,Yang H,Wei W,Liang M,Shi J,Liu R,Li R,Zhang Y,Liu J,Shi X,Wan R,Fu Y,Xie R,Wang Y
Sat Jul 16 00:00:00 EDT 2022
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
Journal of agricultural and food chemistry
Li R,Xiao J,Cao Y,Huang Q,Ho CT,Lu M
Wed Jan 26 00:00:00 EST 2022
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
Cancer cell international
Liu Z,Wang Q,Zhai G,Ke S,Yu X,Guo J
Sat Mar 19 00:00:00 EDT 2022
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells.
Cancer chemotherapy and pharmacology
Zhang W,Liu J,Li Y,Guo F
Thu Sep 01 00:00:00 EDT 2022
Curcumin represses lipid accumulation through inhibiting ERK1/2-PPAR-γ signaling pathway and triggering apoptosis in porcine subcutaneous preadipocytes.
Animal bioscience
Pan S,Chen Y,Zhang L,Liu Z,Xu X,Xing H
Sun May 01 00:00:00 EDT 2022
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Journal of ethnopharmacology
Zhao CZ,Jiang W,Zhu YY,Wang CZ,Zhong WH,Wu G,Chen J,Zhu MN,Wu QL,Du XL,Luo YY,Li M,Wang HL,Zhao H,Ma QG,Zhong GY,Wei RR
Fri Mar 25 00:00:00 EDT 2022
SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness.
Translational oncology
Chen Y,Zhao M,Zhang L,Shen D,Xu X,Yi Q,Tang L
Tue Mar 01 00:00:00 EST 2022
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Cell
Cui C,Chakraborty K,Tang XA,Zhou G,Schoenfelt KQ,Becker KM,Hoffman A,Chang YF,Blank A,Reardon CA,Kenny HA,Vaisar T,Lengyel E,Greene G,Becker L
Thu Jun 10 00:00:00 EDT 2021
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Journal of cellular and molecular medicine
Zhang J,Yang S,Guan H,Zhou J,Gao Y
Mon Feb 01 00:00:00 EST 2021
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Food & function
Zhang X,Xia H,Wang J,Leng R,Zhou X,Gao Q,He K,Liu D,Huang B
Mon Mar 15 00:00:00 EDT 2021
AGEs exacerbates coronary microvascular dysfunction in NoCAD by activating endoplasmic reticulum stress-mediated PERK signaling pathway.
Metabolism: clinical and experimental
Liu Z,Zhu H,Ma Y,Tang Z,Zhao N,Wang Y,Pan S
Thu Apr 01 00:00:00 EDT 2021
Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway.
Cell biology international
Li H,Niu N,Yang J,Dong F,Zhang T,Li S,Zhao W
Sun Aug 01 00:00:00 EDT 2021
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Nutrients
Lin L,Zeng L,Liu A,Yuan D,Peng Y,Zhang S,Li Y,Chen J,Xiao W,Gong Z
Wed Nov 17 00:00:00 EST 2021
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Evidence-based complementary and alternative medicine : eCAM
Lei SS,Zhang NY,Zhou FC,He X,Wang HY,Li LZ,Zheng X,Dong YJ,Luo R,Li B,Jin HY,Yu QX,Lv GY,Chen SH
Tue Jun 15 00:00:00 EDT 2021
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Stem cells (Dayton, Ohio)
Luo H,Chen CY,Li X,Zhang X,Su CW,Liu Y,Cao T,Hao L,Wang M,Kang JX
Wed Dec 01 00:00:00 EST 2021
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Stem cells (Dayton, Ohio)
Luo H,Chen CY,Li X,Zhang X,Su CW,Liu Y,Cao T,Hao L,Wang M,Kang JX
Wed Dec 01 00:00:00 EST 2021
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Stem cells (Dayton, Ohio)
Luo H,Chen CY,Li X,Zhang X,Su CW,Liu Y,Cao T,Hao L,Wang M,Kang JX
Wed Dec 01 00:00:00 EST 2021
Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids.
Stem cells (Dayton, Ohio)
Luo H,Chen CY,Li X,Zhang X,Su CW,Liu Y,Cao T,Hao L,Wang M,Kang JX
Wed Dec 01 00:00:00 EST 2021
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
Life sciences
Zheng X,Liu D
Fri Jan 15 00:00:00 EST 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 EDT 2021
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Acta pharmacologica Sinica
Dong JY,Xia KJ,Liang W,Liu LL,Yang F,Fang XS,Xiong YJ,Wang L,Zhou ZJ,Li CY,Zhang WD,Wang JY,Chen DP
Wed Sep 01 00:00:00 EDT 2021
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Journal of natural medicines
Jiang MJ,Li L,Huang WF,Su J,Li YH,Qu XS,Fan LL
Wed Sep 01 00:00:00 EDT 2021
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx.
Cancer letters
Yang F,Duan M,Zheng F,Yu L,Wang Y,Wang G,Lin J,Han S,Gan D,Meng Z,Zhu S
Wed Dec 01 00:00:00 EST 2021
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx.
Cancer letters
Yang F,Duan M,Zheng F,Yu L,Wang Y,Wang G,Lin J,Han S,Gan D,Meng Z,Zhu S
Wed Dec 01 00:00:00 EST 2021
c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis.
Clinical and translational medicine
Zhang L,Wang X,Li Y,Han J,Gao X,Li S,Wang F
Wed Sep 01 00:00:00 EDT 2021
Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells.
Ecotoxicology and environmental safety
Qi W,Xu Q,Xu Y,Wang Z,Yang L,Guo S,Shi Y,Zhao T,Zhou L,Ye L
Fri Jan 15 00:00:00 EST 2021
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Human cell
Cheng L,Yu P,Li F,Jiang X,Jiao X,Shen Y,Lai X
Mon Nov 01 00:00:00 EDT 2021
Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription.
International journal of biological sciences
Hou P,Lin T,Meng S,Shi M,Chen F,Jiang T,Li Z,Li M,Chu S,Zheng J,Bai J
Fri Mar 25 00:00:00 EDT 2022
3'-Sulfo-TF Antigen Determined by GAL3ST2/ST3GAL1 Is Essential for Antitumor Activity of Fungal Galectin AAL/AAGL.
ACS omega
Li Y,Li Y,Xia J,Yang Q,Chen Y,Sun H
Tue Jul 13 00:00:00 EDT 2021
Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
Journal of animal science
Pan S,Zhang L,Liu Z,Xing H
Wed Dec 01 00:00:00 EST 2021
Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation.
Translational cancer research
Han J,Kan J,Wang X,Yuan Q,Song X,Huang M,Wu H
Sat Aug 01 00:00:00 EDT 2020
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Frontiers in pharmacology
Chen K,Ma Z,Yan X,Liu J,Xu W,Li Y,Dai Y,Zhang Y,Xiao H
Thu Apr 14 00:00:00 EDT 2022
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
Frontiers in endocrinology
Wang C,Song D,Fu J,Wen X
Wed May 19 00:00:00 EDT 2021
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
International immunopharmacology
Feng Z,Pang L,Chen S,Pang X,Huang Y,Qiao Q,Wang Y,Vonglorkham S,Huang Q,Lin X,Wei J
Sun Nov 01 00:00:00 EDT 2020
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Cell proliferation
Peng F,Zhang N,Wang C,Wang X,Huang W,Peng C,He G,Han B
Wed Jan 01 00:00:00 EST 2020
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Chinese medicine
Lin HY,Han HW,Wang YS,He DL,Sun WX,Feng L,Wen ZL,Yang MK,Lu GH,Wang XM,Qi JL,Yang YH
Wed Apr 13 00:00:00 EDT 2022
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Colon Adenocarcinoma Metastasis.
Frontiers in cell and developmental biology
Chang Z,Huang R,Fu W,Li J,Ji G,Huang J,Shi W,Yin H,Wang W,Meng T,Huang Z,Wei Q,Qin H
Sat Apr 16 00:00:00 EDT 2022
miR-196b-5p-mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling.
Cell death & disease
Huang X,Xiao S,Zhu X,Yu Y,Cao M,Zhang X,Li S,Zhu W,Wu F,Zheng X,Jin L,Xie C,Huang X,Zou P,Li X,Cui R
Tue Sep 22 00:00:00 EDT 2020
miR-196b-5p-mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling.
Cell death & disease
Huang X,Xiao S,Zhu X,Yu Y,Cao M,Zhang X,Li S,Zhu W,Wu F,Zheng X,Jin L,Xie C,Huang X,Zou P,Li X,Cui R
Tue Sep 22 00:00:00 EDT 2020
FGF9 knockout in GABAergic neurons induces apoptosis and inflammation via the Fas/caspase-3 pathway in the cerebellum of mice.
Brain research bulletin
Guo M,Chen H,Duan W,Li Z,Li Y,Ma Y,Xu X,Yi L,Bi Y,Liu Y,Zhang J,Li C
Wed Jan 01 00:00:00 EST 2020
Inhibition of microRNA-327 ameliorates ischemia/reperfusion injury-induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain.
Journal of cellular physiology
Li Q,Yang J,Zhang J,Liu XW,Yang CJ,Fan ZX,Wang HB,Yang Y,Zheng T,Yang J
Wed Apr 01 00:00:00 EDT 2020
C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells.
International journal of molecular sciences
Kim HJ,Seo BG,Kim KD,Yoo J,Lee JH,Min BS,Lee JH,Hwangbo C
Fri Feb 14 00:00:00 EST 2020
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Life sciences
Wang B,Xu H,Hu X,Ma W,Zhang J,Li Y,Yu M,Zhang Y,Li X,Ye X
Sun Mar 15 00:00:00 EDT 2020
Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity.
OncoTargets and therapy
Li H,An X,Zhang D,Li Q,Zhang N,Yu H,Li Z
Wed Apr 13 00:00:00 EDT 2022
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Journal of physiology and biochemistry
Wang L,Li S,Yu X,Han Y,Wu Y,Wang S,Chen X,Zhang J,Wang S
Sat Jun 01 00:00:00 EDT 2019
MicroRNA-128 is involved in dexamethasone-induced lipid accumulation via repressing SIRT1 expression in cultured pig preadipocytes.
The Journal of steroid biochemistry and molecular biology
Pan S,Cui Y,Fu Z,Zhang L,Xing H
Fri Feb 01 00:00:00 EST 2019
MicroRNA-128 is involved in dexamethasone-induced lipid accumulation via repressing SIRT1 expression in cultured pig preadipocytes.
The Journal of steroid biochemistry and molecular biology
Pan S,Cui Y,Fu Z,Zhang L,Xing H
Fri Feb 01 00:00:00 EST 2019
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Biochemical pharmacology
Liu Y,Fan D
Tue Oct 01 00:00:00 EDT 2019
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Frontiers in pharmacology
Li B,He X,Lei SS,Zhou FC,Zhang NY,Chen YH,Wang YZ,Su J,Yu JJ,Li LZ,Zheng X,Luo R,Kołodyńska D,Xiong S,Lv GY,Chen SH
Mon Sep 28 00:00:00 EDT 2020
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Frontiers in pharmacology
Li B,He X,Lei SS,Zhou FC,Zhang NY,Chen YH,Wang YZ,Su J,Yu JJ,Li LZ,Zheng X,Luo R,Kołodyńska D,Xiong S,Lv GY,Chen SH
Mon Sep 28 00:00:00 EDT 2020
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
BMC complementary and alternative medicine
Que Z,Zhou Z,Luo B,Dong C,Jiang Y,Li H,Tian J
Wed Aug 07 00:00:00 EDT 2019
Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice.
Experimental and therapeutic medicine
Deng C,Li J,Li L,Sun F,Xie J
Sat Jun 01 00:00:00 EDT 2019
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Experimental & molecular medicine
Wu X,Liao Z,Wang K,Hua W,Liu X,Song Y,Zhang Y,Yang S,Yang C
Wed Sep 25 00:00:00 EDT 2019
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Experimental & molecular medicine
Wu X,Liao Z,Wang K,Hua W,Liu X,Song Y,Zhang Y,Yang S,Yang C
Wed Sep 25 00:00:00 EDT 2019
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Experimental and therapeutic medicine
Lu J,Meng Z,Cheng B,Liu M,Tao S,Guan S
Tue Oct 01 00:00:00 EDT 2019
Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism.
Frontiers in pharmacology
Qiao X,Zhou ZC,Niu R,Su YT,Sun Y,Liu HL,Teng JL,Ye JN,Shi H,Yang CD,Cheng XB
Tue Sep 29 00:00:00 EDT 2020
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Cell research
Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J
Wed Aug 01 00:00:00 EDT 2018
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Cell research
Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J
Wed Aug 01 00:00:00 EDT 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 EST 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 EST 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 EST 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 EST 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Molecular pharmaceutics
Li LN,Wang L,Cheng YN,Cao ZQ,Zhang XK,Guo XL
Mon Nov 05 00:00:00 EST 2018
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Molecular pharmaceutics
Li LN,Wang L,Cheng YN,Cao ZQ,Zhang XK,Guo XL
Mon Nov 05 00:00:00 EST 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
European journal of nutrition
Pan S,Jia Y,Yang X,Cai D,Liu Z,Song H,Zhao R
Sun Apr 01 00:00:00 EDT 2018
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
European journal of nutrition
Pan S,Jia Y,Yang X,Cai D,Liu Z,Song H,Zhao R
Sun Apr 01 00:00:00 EDT 2018
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Human cell
Yang Y,Yang H,Xu M,Zhang H,Sun M,Mu P,Dong T,Du S,Liu K
Sun Jul 01 00:00:00 EDT 2018
Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Human cell
Yang Y,Yang H,Xu M,Zhang H,Sun M,Mu P,Dong T,Du S,Liu K
Sun Jul 01 00:00:00 EDT 2018
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Oncology letters
Yin LL,Wen XM,Li M,Xu YM,Zhao XF,Li J,Wang XW
Thu Nov 01 00:00:00 EDT 2018
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Oncology letters
Yin LL,Wen XM,Li M,Xu YM,Zhao XF,Li J,Wang XW
Thu Nov 01 00:00:00 EDT 2018
6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE-/- Mice Exposed to Chronic Mild Stress.
Cardiovascular toxicology
Wang S,Tian M,Yang R,Jing Y,Chen W,Wang J,Zheng X,Wang F
Mon Oct 01 00:00:00 EDT 2018
6-Gingerol Ameliorates Behavioral Changes and Atherosclerotic Lesions in ApoE-/- Mice Exposed to Chronic Mild Stress.
Cardiovascular toxicology
Wang S,Tian M,Yang R,Jing Y,Chen W,Wang J,Zheng X,Wang F
Mon Oct 01 00:00:00 EDT 2018
Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo.
Journal of experimental & clinical cancer research : CR
Chen Z,You L,Wang L,Huang X,Liu H,Wei JY,Zhu L,Qian W
Mon Aug 13 00:00:00 EDT 2018
Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo.
Journal of experimental & clinical cancer research : CR
Chen Z,You L,Wang L,Huang X,Liu H,Wei JY,Zhu L,Qian W
Mon Aug 13 00:00:00 EDT 2018
Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis.
The FEBS journal
Zhong H,Chen K,Feng M,Shao W,Wu J,Chen K,Liang T,Liu C
Thu Feb 01 00:00:00 EST 2018
Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Biochemical and biophysical research communications
Kong M,Chen X,Xu H,Fang M,Xu Y
Mon Sep 03 00:00:00 EDT 2018
MicroRNA‑143 increases cell apoptosis in myelodysplastic syndrome through the Fas/FasL pathway both in vitro and in vivo.
International journal of oncology
Cui J,Wei C,Deng L,Kuang X,Zhang Z,Pierides C,Chi J,Wang L
Thu Nov 01 00:00:00 EDT 2018
Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
Cell death & disease
Verlekar D,Wei SJ,Cho H,Yang S,Kang MH
Tue Sep 11 00:00:00 EDT 2018
Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
Cell death & disease
Verlekar D,Wei SJ,Cho H,Yang S,Kang MH
Tue Sep 11 00:00:00 EDT 2018
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Oxidative medicine and cellular longevity
Jiang Z,Song F,Li Y,Xue D,Zhao N,Zhang J,Deng G,Li M,Liu X,Wang Y
Thu Apr 20 00:00:00 EDT 2017
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Oxidative medicine and cellular longevity
Jiang Z,Song F,Li Y,Xue D,Zhao N,Zhang J,Deng G,Li M,Liu X,Wang Y
Thu Apr 20 00:00:00 EDT 2017
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
Food & function
Shen R,Liu D,Hou C,Liu D,Zhao L,Cheng J,Wang D,Bai D
Wed Oct 18 00:00:00 EDT 2017
Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo.
Food & function
Shen R,Liu D,Hou C,Liu D,Zhao L,Cheng J,Wang D,Bai D
Wed Oct 18 00:00:00 EDT 2017
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen S,Wen X,Zhang W,Wang C,Liu J,Liu C
Wed Mar 01 00:00:00 EST 2017
Hypolipidemic effect of oleanolic acid is mediated by the miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen S,Wen X,Zhang W,Wang C,Liu J,Liu C
Wed Mar 01 00:00:00 EST 2017
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Cellular microbiology
Liu X,Ding S,Shi P,Dietrich R,Märtlbauer E,Zhu K
Sat Apr 01 00:00:00 EDT 2017
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Cellular microbiology
Liu X,Ding S,Shi P,Dietrich R,Märtlbauer E,Zhu K
Sat Apr 01 00:00:00 EDT 2017
11β-hydroxysteroid dehydrogenases-2 decreases the apoptosis of MC3T3/MLO-Y4 cells induced by glucocorticoids.
Biochemical and biophysical research communications
Zhang H,Zhou F,Pan Z,Bu X,Wang Y,Chen F
Sat Sep 02 00:00:00 EDT 2017
11β-hydroxysteroid dehydrogenases-2 decreases the apoptosis of MC3T3/MLO-Y4 cells induced by glucocorticoids.
Biochemical and biophysical research communications
Zhang H,Zhou F,Pan Z,Bu X,Wang Y,Chen F
Sat Sep 02 00:00:00 EDT 2017
Loss of Fas expression and high expression of HLA-E promoting the immune escape of early colorectal cancer cells.
Oncology letters
Huang R,Zhang D,Li F,Xiao Z,Wu M,Shi D,Xiang P,Bao Z
Mon May 01 00:00:00 EDT 2017
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Oncotarget
Pan S,Cui Y,Dong X,Zhang T,Xing H
Fri Oct 20 00:00:00 EDT 2017
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Oncotarget
Pan S,Cui Y,Dong X,Zhang T,Xing H
Fri Oct 20 00:00:00 EDT 2017
BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.
Theriogenology
Lei X,Cui K,Li Z,Su J,Jiang J,Zhang H,Liu Q,Shi D
Tue Mar 15 00:00:00 EDT 2016
BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.
Theriogenology
Lei X,Cui K,Li Z,Su J,Jiang J,Zhang H,Liu Q,Shi D
Tue Mar 15 00:00:00 EDT 2016
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Reproduction in domestic animals = Zuchthygiene
Lei X,Cui K,Liu Q,Zhang H,Li Z,Huang B,Shi D
Mon Feb 01 00:00:00 EST 2016
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Reproduction in domestic animals = Zuchthygiene
Lei X,Cui K,Liu Q,Zhang H,Li Z,Huang B,Shi D
Mon Feb 01 00:00:00 EST 2016
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Scientific reports
Ding C,Zhao Y,Shi X,Zhang N,Zu G,Li Z,Zhou J,Gao D,Lv L,Tian X,Yao J
Mon Jun 27 00:00:00 EDT 2016
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Scientific reports
Ding C,Zhao Y,Shi X,Zhang N,Zu G,Li Z,Zhou J,Gao D,Lv L,Tian X,Yao J
Mon Jun 27 00:00:00 EDT 2016
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Y,Du Y,Zhang X,Bai L,Mibrahim M,Zhang J,Wei Y,Li C,Fan S,Wang H,Zhao Z,Tang J
Sun Mar 01 00:00:00 EST 2015
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Y,Du Y,Zhang X,Bai L,Mibrahim M,Zhang J,Wei Y,Li C,Fan S,Wang H,Zhao Z,Tang J
Sun Mar 01 00:00:00 EST 2015
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Chemical research in toxicology
Song X,Li L,Shi Q,Lehmler HJ,Fu J,Su C,Xia X,Song E,Song Y
Mon Nov 16 00:00:00 EST 2015
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Chemical research in toxicology
Song X,Li L,Shi Q,Lehmler HJ,Fu J,Su C,Xia X,Song E,Song Y
Mon Nov 16 00:00:00 EST 2015
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Chronobiology international
Wang D,Chen S,Liu M,Liu C
Mon Jun 01 00:00:00 EDT 2015
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Chronobiology international
Wang D,Chen S,Liu M,Liu C
Mon Jun 01 00:00:00 EDT 2015
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Molecular medicine reports
Liang ZE,Yi YJ,Guo YT,Wang RC,Hu QL,Xiong XY
Sun Nov 01 00:00:00 EDT 2015
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.
Molecular medicine reports
Liang ZE,Yi YJ,Guo YT,Wang RC,Hu QL,Xiong XY
Sun Nov 01 00:00:00 EDT 2015
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
International journal of molecular sciences
Ma Z,Hou T,Shi W,Liu W,He H
Fri Sep 11 00:00:00 EDT 2015
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
International journal of molecular sciences
Ma Z,Hou T,Shi W,Liu W,He H
Fri Sep 11 00:00:00 EDT 2015
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Nanoscale research letters
Zhang M,Yang J,Shu J,Fu C,Liu S,Xu G,Zhang D
Fri Nov 21 00:00:00 EST 2014
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Nanoscale research letters
Zhang M,Yang J,Shu J,Fu C,Liu S,Xu G,Zhang D
Fri Nov 21 00:00:00 EST 2014
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Asian Pacific journal of cancer prevention : APJCP
Liang Z,Guo YT,Yi YJ,Wang RC,Hu QL,Xiong XY
Thu Mar 31 00:00:00 EDT 2016
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Asian Pacific journal of cancer prevention : APJCP
Liang Z,Guo YT,Yi YJ,Wang RC,Hu QL,Xiong XY
Thu Mar 31 00:00:00 EDT 2016
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Diabetes
Wang Q,Dong Z,Liu X,Song X,Song Q,Shang Q,Jiang Y,Guo C,Zhang L
Sun Dec 01 00:00:00 EST 2013
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Diabetes
Wang Q,Dong Z,Liu X,Song X,Song Q,Shang Q,Jiang Y,Guo C,Zhang L
Sun Dec 01 00:00:00 EST 2013
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
PloS one
Yang X,Xu Y,Guo F,Ning Y,Zhi X,Yin L,Li X
Thu Oct 17 00:00:00 EDT 2013
Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo.
PloS one
Yang X,Xu Y,Guo F,Ning Y,Zhi X,Yin L,Li X
Thu Oct 17 00:00:00 EDT 2013
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bucciantini M,Nosi D,Forzan M,Russo E,Calamai M,Pieri L,Formigli L,Quercioli F,Soria S,Pavone F,Savistchenko J,Melki R,Stefani M
Wed Feb 01 00:00:00 EST 2012
Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bucciantini M,Nosi D,Forzan M,Russo E,Calamai M,Pieri L,Formigli L,Quercioli F,Soria S,Pavone F,Savistchenko J,Melki R,Stefani M
Wed Feb 01 00:00:00 EST 2012
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G
Thu Dec 01 00:00:00 EST 2011
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G
Thu Dec 01 00:00:00 EST 2011
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Biochemical pharmacology
Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G
Thu Jul 15 00:00:00 EDT 2010
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Biochemical pharmacology
Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G
Thu Jul 15 00:00:00 EDT 2010
