Product References
Proteomic Profiling of Fallopian Tube-Derived Extracellular Vesicles Using a Microfluidic Tissue-on-Chip System.
Bioengineering (Basel, Switzerland)
Zha D,Rayamajhi S,Sipes J,Russo A,Pathak HB,Li K,Sardiu ME,Bantis LE,Mitra A,Puri RV,Trinidad CV,Cain BP,Isenberg BC,Coppeta J,MacLaughlan S,Godwin AK,Burdette JE
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry (Paraffin)
Mon Mar 27 00:00:00 EDT 2023
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Cell
Wu CT,Lidsky PV,Xiao Y,Cheng R,Lee IT,Nakayama T,Jiang S,He W,Demeter J,Knight MG,Turn RE,Rojas-Hernandez LS,Ye C,Chiem K,Shon J,Martinez-Sobrido L,Bertozzi CR,Nolan GP,Nayak JV,Milla C,Andino R,Jackson PK
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that motile cilia, microvilli, and mucociliary-dependent mucus flow are critical for efficient virus replication in nasal epithelia.
Thu Jan 05 00:00:00 EST 2023
A local translation program regulates centriole amplification in the airway epithelium.
Scientific reports
Liu H,Li H,Jiang Z,Jin S,Song R,Yang Y,Li J,Huang J,Zhang X,Dong X,Mori M,Fritzler MJ,He L,Cardoso WV,Lu J
14-9965-82 was used in Immunohistochemistry to identify Trinucleotide repeat containing-6a (Tnrc6a), a component of the miRNA pathway, distinctively localized to apical granules of differentiating airway multiciliated cells (MCCs) adjacent to centrioles.
Mon May 01 00:00:00 EDT 2023
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Nature
Albers S,Allen EC,Bharti N,Davyt M,Joshi D,Perez-Garcia CG,Santos L,Mukthavaram R,Delgado-Toscano MA,Molina B,Kuakini K,Alayyoubi M,Park KJ,Acharya G,Gonzalez JA,Sagi A,Birket SE,Tearney GJ,Rowe SM,Manfredi C,Hong JS,Tachikawa K,Karmali P,Matsuda D,Sorscher EJ,Chivukula P,Ignatova Z
14-9965-82 was used in Immunohistochemistry-immunofluorescence to provide a framework for the development of tRNA-based therapies with a high molecular safety profile and high efficacy in targeted PTC suppression.
Thu Jun 01 00:00:00 EDT 2023
A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution.
Respiratory research
Prescott RA,Pankow AP,de Vries M,Crosse KM,Patel RS,Alu M,Loomis C,Torres V,Koralov S,Ivanova E,Dittmann M,Rosenberg BR
14-9965-82 was used in Immunohistochemistry-immunofluorescence to support BCi-NS1.1-derived HAE cultures as a valuable tool for the study of airway infectious disease.
Mon Aug 28 00:00:00 EDT 2023
Heterozygous FOXJ1 Mutations Cause Incomplete Ependymal Cell Differentiation and Communicating Hydrocephalus.
Cellular and molecular neurobiology
Hou CC,Li D,Berry BC,Zheng S,Carroll RS,Johnson MD,Yang HW
14-9965-82 was used in Immunohistochemistry to show that heterozygous FOXJ1 mutations are also associated with communicating hydrocephalus in humans and cause communicating hydrocephalus in mice.
Wed Nov 01 00:00:00 EDT 2023
An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Development (Cambridge, England)
Yin W,Liontos A,Koepke J,Ghoul M,Mazzocchi L,Liu X,Lu C,Wu H,Fysikopoulos A,Sountoulidis A,Seeger W,Ruppert C,Günther A,Stainier DYR,Samakovlis C
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Feb 01 00:00:00 EST 2022
An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Development (Cambridge, England)
Yin W,Liontos A,Koepke J,Ghoul M,Mazzocchi L,Liu X,Lu C,Wu H,Fysikopoulos A,Sountoulidis A,Seeger W,Ruppert C,Günther A,Stainier DYR,Samakovlis C
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Feb 01 00:00:00 EST 2022
An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Development (Cambridge, England)
Yin W,Liontos A,Koepke J,Ghoul M,Mazzocchi L,Liu X,Lu C,Wu H,Fysikopoulos A,Sountoulidis A,Seeger W,Ruppert C,Günther A,Stainier DYR,Samakovlis C
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Feb 01 00:00:00 EST 2022
Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
iScience
Serra CFH,Liu H,Qian J,Mori M,Lu J,Cardoso WV
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Fri Aug 19 00:00:00 EDT 2022
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Cell stem cell
Han Y,Tan L,Zhou T,Yang L,Carrau L,Lacko LA,Saeed M,Zhu J,Zhao Z,Nilsson-Payant BE,Lira Neto FT,Cahir C,Giani AM,Chai JC,Li Y,Dong X,Moroziewicz D,Paull D,Zhang T,Koo S,Tan C,Danziger R,Ba Q,Feng L,Chen Z,Zhong A,Wise GJ,Xiang JZ,Wang H,Schwartz RE,tenOever BR,Noggle SA,Rice CM,Qi Q,Evans T,Chen S
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Thu Oct 06 00:00:00 EDT 2022
An IGF1-expressing endometrial stromal cell population is associated with human decidualization.
BMC biology
Shi JW,Lai ZZ,Yang HL,Zhou WJ,Zhao XY,Xie F,Liu SP,Chen WD,Zhang T,Ye JF,Zhou XY,Li MQ
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Thu Dec 08 00:00:00 EST 2022
Engineering rotating apical-out airway organoid for assessing respiratory cilia motility.
iScience
Wijesekara P,Yadav P,Perkins LA,Stolz DB,Franks JM,Watkins SC,Reinoso Jacome E,Brody SL,Horani A,Xu J,Barati Farimani A,Ren X
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Fri Aug 19 00:00:00 EDT 2022
Engineering rotating apical-out airway organoid for assessing respiratory cilia motility.
iScience
Wijesekara P,Yadav P,Perkins LA,Stolz DB,Franks JM,Watkins SC,Reinoso Jacome E,Brody SL,Horani A,Xu J,Barati Farimani A,Ren X
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Fri Aug 19 00:00:00 EDT 2022
PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells.
eLife
LoMastro GM,Drown CG,Maryniak AL,Jewett CE,Strong MA,Holland AJ
14-9965-82 was used in Immunohistochemistry-immunofluorescence to show that the initial stages of centriole assembly are conserved between cycling cells and MCCs and suggest that centriole amplification and surface area expansion are coordinated events.
Mon Aug 15 00:00:00 EDT 2022
PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells.
eLife
LoMastro GM,Drown CG,Maryniak AL,Jewett CE,Strong MA,Holland AJ
14-9965-82 was used in Immunohistochemistry-immunofluorescence to show that the initial stages of centriole assembly are conserved between cycling cells and MCCs and suggest that centriole amplification and surface area expansion are coordinated events.
Mon Aug 15 00:00:00 EDT 2022
Cell-intrinsic differences between human airway epithelial cells from children and adults.
iScience
Maughan EF,Hynds RE,Pennycuick A,Nigro E,Gowers KHC,Denais C,Gómez-López S,Lazarus KA,Orr JC,Pearce DR,Clarke SE,Lee DDH,Woodall MNJ,Masonou T,Case KM,Teixeira VH,Hartley BE,Hewitt RJ,Al Yaghchi C,Sandhu GS,Birchall MA,O'Callaghan C,Smith CM,De Coppi P,Butler CR,Janes SM
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Fri Nov 18 00:00:00 EST 2022
Epithelial Wntless regulates postnatal alveologenesis.
Development (Cambridge, England)
Fang Y,Shao H,Wu Q,Wong NC,Tsong N,Sime PJ,Que J
14-9965-82 was used in Immunohistochemistry-immunofluorescence to provide initial evidence that epithelial-derived Wnts are crucial for the differentiation of the surrounding mesenchyme during early postnatal alveologenesis.
Sat Jan 01 00:00:00 EST 2022
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential.
Developmental cell
Frederico B,Martins I,Chapela D,Gasparrini F,Chakravarty P,Ackels T,Piot C,Almeida B,Carvalho J,Ciccarelli A,Peddie CJ,Rogers N,Briscoe J,Guillemot F,Schaefer AT,Saúde L,Reis e Sousa C
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to report that DNGR-1 lineage tracing in mice identifies an ependymal cell subset, wherein resides latent regenerative potential.
Mon Aug 22 00:00:00 EDT 2022
EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation.
eLife
Pribluda A,Daemen A,Lima AN,Wang X,Hafner M,Poon C,Modrusan Z,Katakam AK,Foreman O,Eastham J,Hung J,Haley B,Garcia JT,Jackson EL,Junttila MR
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal EHMT2 as a critical regulator of Wnt signaling, implicating Ehmt2 as a potential target in lung cancer and other AT2-mediated lung pathologies.
Fri Aug 19 00:00:00 EDT 2022
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation.
eLife
Zhou Y,Yang Y,Guo L,Qian J,Ge J,Sinner D,Ding H,Califano A,Cardoso WV
14-9965-82 was used in Immunohistochemistry-immunofluorescence to provide novel insights into the origin and impact of basal cell heterogeneity on the establishment of regionally distinct responses of the airway epithelium during injury-repair and in disease conditions.
Fri Sep 30 00:00:00 EDT 2022
Ependyma: a new target for autoantibodies in neuromyelitis optica?
Brain communications
Bigotte M,Gimenez M,Gavoille A,Deligiannopoulou A,El Hajj A,Croze S,Goumaidi A,Malleret G,Salin P,Giraudon P,Ruiz A,Marignier R
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to find that antibodies from NMO patients on ependymal cells suggesting that key role for ependymal cells in the early phase of NMO lesion formation.
Thu Feb 09 00:00:00 EST 2023
Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.
Current protocols
Ngan SY,Quach HT,Laselva O,Huang EN,Mangos M,Xia S,Bear CE,Wong AP
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to optimize previously published protocols to efficiently generate three developmental stages of the lung model (fetal lung epithelial progenitors, fLEP; immature airway epithelial spheroid, AES; air-liquid interface culture, ALI), and demonstrate its potential for cystic fibrosis (CF) drug discovery platforms.
Sat Jan 01 00:00:00 EST 2022
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus.
Nature neuroscience
Duy PQ,Weise SC,Marini C,Li XJ,Liang D,Dahl PJ,Ma S,Spajic A,Dong W,Juusola J,Kiziltug E,Kundishora AJ,Koundal S,Pedram MZ,Torres-Fernández LA,Händler K,De Domenico E,Becker M,Ulas T,Juranek SA,Cuevas E,Hao LT,Jux B,Sousa AMM,Liu F,Kim SK,Li M,Yang Y,Takeo Y,Duque A,Nelson-Williams C,Ha Y,Selvaganesan K,Robert SM,Singh AK,Allington G,Furey CG,Timberlake AT,Reeves BC,Smith H,Dunbar A,DeSpenza T,Goto J,Marlier A,Moreno-De-Luca A,Yu X,Butler WE,Carter BS,Lake EMR,Constable RT,Rakic P,Lin H,Deniz E,Benveniste H,Malvankar NS,Estrada-Veras JI,Walsh CA,Alper SL,Schultze JL,Paeschke K,Doetzlhofer A,Wulczyn FG,Jin SC,Lifton RP,Sestan N,Kolanus W,Kahle KT
14-9965-82 was used in Immunohistochemistry-immunofluorescence to highlight the importance of precisely regulated neuroepithelial cell fate for normal brain-CSF biomechanics and support a clinically relevant neuroprogenitor-based paradigm of CH.
Fri Apr 01 00:00:00 EDT 2022
Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.
Nature medicine
Carraro G,Langerman J,Sabri S,Lorenzana Z,Purkayastha A,Zhang G,Konda B,Aros CJ,Calvert BA,Szymaniak A,Wilson E,Mulligan M,Bhatt P,Lu J,Vijayaraj P,Yao C,Shia DW,Lund AJ,Israely E,Rickabaugh TM,Ernst J,Mense M,Randell SH,Vladar EK,Ryan AL,Plath K,Mahoney JE,Stripp BR,Gomperts BN
14-9965-82 was used in Immunohistochemistry to yield a molecular atlas of the proximal airway epithelium that will provide insights for the development of new targeted therapies for CF airway disease.
Sat May 01 00:00:00 EDT 2021
Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4.
The EMBO journal
Ohlig S,Clavreul S,Thorwirth M,Simon-Ebert T,Bocchi R,Ulbricht S,Kannayian N,Rossner M,Sirko S,Smialowski P,Fischer-Sternjak J,Götz M
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Nov 02 00:00:00 EDT 2021
Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4.
The EMBO journal
Ohlig S,Clavreul S,Thorwirth M,Simon-Ebert T,Bocchi R,Ulbricht S,Kannayian N,Rossner M,Sirko S,Smialowski P,Fischer-Sternjak J,Götz M
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Nov 02 00:00:00 EDT 2021
Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells.
Frontiers in cell and developmental biology
Mateos-Quiros CM,Garrido-Jimenez S,Álvarez-Hernán G,Diaz-Chamorro S,Barrera-Lopez JF,Francisco-Morcillo J,Roman AC,Centeno F,Carvajal-Gonzalez JM
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Aug 17 00:00:00 EDT 2021
Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells.
Frontiers in cell and developmental biology
Mateos-Quiros CM,Garrido-Jimenez S,Álvarez-Hernán G,Diaz-Chamorro S,Barrera-Lopez JF,Francisco-Morcillo J,Roman AC,Centeno F,Carvajal-Gonzalez JM
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Aug 17 00:00:00 EDT 2021
Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells.
Frontiers in cell and developmental biology
Mateos-Quiros CM,Garrido-Jimenez S,Álvarez-Hernán G,Diaz-Chamorro S,Barrera-Lopez JF,Francisco-Morcillo J,Roman AC,Centeno F,Carvajal-Gonzalez JM
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Aug 17 00:00:00 EDT 2021
BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors.
Scientific reports
Omiya H,Yamaguchi S,Watanabe T,Kuniya T,Harada Y,Kawaguchi D,Gotoh Y
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Jan 12 00:00:00 EST 2021
Distribution of Aldh1L1-CreERT2 Recombination in Astrocytes Versus Neural Stem Cells in the Neurogenic Niches of the Adult Mouse Brain.
Frontiers in neuroscience
Beyer F,Lüdje W,Karpf J,Saher G,Beckervordersandforth R
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Sat Sep 25 00:00:00 EDT 2021
Distribution of Aldh1L1-CreERT2 Recombination in Astrocytes Versus Neural Stem Cells in the Neurogenic Niches of the Adult Mouse Brain.
Frontiers in neuroscience
Beyer F,Lüdje W,Karpf J,Saher G,Beckervordersandforth R
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Sat Sep 25 00:00:00 EDT 2021
Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis.
Cell reports
Hicks-Berthet J,Ning B,Federico A,Tilston-Lunel A,Matschulat A,Ai X,Lenburg ME,Beane J,Monti S,Varelas X
14-9965-82 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify YAP/TAZ as critical factors in lung epithelial homeostasis and offer molecular insight into the mechanisms promoting goblet cell differentiation, which is a hallmark of many lung diseases.
Tue Jul 13 00:00:00 EDT 2021
Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis.
Cell reports
Hicks-Berthet J,Ning B,Federico A,Tilston-Lunel A,Matschulat A,Ai X,Lenburg ME,Beane J,Monti S,Varelas X
14-9965-82 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify YAP/TAZ as critical factors in lung epithelial homeostasis and offer molecular insight into the mechanisms promoting goblet cell differentiation, which is a hallmark of many lung diseases.
Tue Jul 13 00:00:00 EDT 2021
ID4 Is Required for Normal Ependymal Cell Development.
Frontiers in neuroscience
Rocamonde B,Herranz-Pérez V,Garcia-Verdugo JM,Huillard E
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Thu May 13 00:00:00 EDT 2021
Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state.
Physiological reports
Omote N,Sakamoto K,Li Q,Schupp JC,Adams T,Ahangari F,Chioccioli M,DeIuliis G,Hashimoto N,Hasegawa Y,Kaminski N
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state.
Physiological reports
Omote N,Sakamoto K,Li Q,Schupp JC,Adams T,Ahangari F,Chioccioli M,DeIuliis G,Hashimoto N,Hasegawa Y,Kaminski N
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state.
Physiological reports
Omote N,Sakamoto K,Li Q,Schupp JC,Adams T,Ahangari F,Chioccioli M,DeIuliis G,Hashimoto N,Hasegawa Y,Kaminski N
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
Androglobin gene expression patterns and FOXJ1-dependent regulation indicate its functional association with ciliogenesis.
The Journal of biological chemistry
Koay TW,Osterhof C,Orlando IMC,Keppner A,Andre D,Yousefian S,Suárez Alonso M,Correia M,Markworth R,Schödel J,Hankeln T,Hoogewijs D
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in ChIP assay
Tue Aug 31 00:00:00 EDT 2021
Androglobin gene expression patterns and FOXJ1-dependent regulation indicate its functional association with ciliogenesis.
The Journal of biological chemistry
Koay TW,Osterhof C,Orlando IMC,Keppner A,Andre D,Yousefian S,Suárez Alonso M,Correia M,Markworth R,Schödel J,Hankeln T,Hoogewijs D
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in ChIP assay
Tue Aug 31 00:00:00 EDT 2021
Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures.
eLife
Gkatzis K,Panza P,Peruzzo S,Stainier DY
14-9965-82 was used in Immunocytochemistry to understand how serum-free culture conditions effect alveolar cell differentiation into mouse-modelled lung organoids.
Wed Sep 29 00:00:00 EDT 2021
Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional.
Nature communications
Stancil IT,Michalski JE,Davis-Hall D,Chu HW,Park JA,Magin CM,Yang IV,Smith BJ,Dobrinskikh E,Schwartz DA
14-9965-82 was used in Immunocytochemistry to illustrate the active mechanisms regulating airway epithelial-driven fibrosis and identify targets to modulate disease progression.
Tue Jul 27 00:00:00 EDT 2021
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
STAR protocols
Manna V,Caradonna S
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry (Paraffin)
Fri Dec 17 00:00:00 EST 2021
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
STAR protocols
Manna V,Caradonna S
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry (Paraffin)
Fri Dec 17 00:00:00 EST 2021
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.
Cell reports
Mulay A,Konda B,Garcia G,Yao C,Beil S,Villalba JM,Koziol C,Sen C,Purkayastha A,Kolls JK,Pociask DA,Pessina P,de Aja JS,Garcia-de-Alba C,Kim CF,Gomperts B,Arumugaswami V,Stripp BR
14-9965-82 was used in Immunohistochemistry to develop primary human lung epithelial infection models to understand initial responses of proximal and distal lung epithelium to SARS-CoV-2 infection.
Tue May 04 00:00:00 EDT 2021
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.
International journal of molecular sciences
Bonilla P,Hernandez J,Giraldo E,González-Pérez MA,Alastrue-Agudo A,Elkhenany H,Vicent MJ,Navarro X,Edel M,Moreno-Manzano V
14-9965-82 was used in Immunocytochemistry to show that the combination of stem cell transplantation and PA-C treatment confers higher neuroprotective effects compared to individual treatments.
Mon May 31 00:00:00 EDT 2021
Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs.
American journal of respiratory and critical care medicine
Carraro G,Mulay A,Yao C,Mizuno T,Konda B,Petrov M,Lafkas D,Arron JR,Hogaboam CM,Chen P,Jiang D,Noble PW,Randell SH,McQualter JL,Stripp BR
14-9965-82 was used in Immunohistochemistry (Paraffin) to to decipher the transcriptome of freshly isolated epithelial cells from normal and IPF lungs to discern disease-dependent changes within basal stem cells.
Tue Dec 01 00:00:00 EST 2020
Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development.
Neuron
Lennox AL,Hoye ML,Jiang R,Johnson-Kerner BL,Suit LA,Venkataramanan S,Sheehan CJ,Alsina FC,Fregeau B,Aldinger KA,Moey C,Lobach I,Afenjar A,Babovic-Vuksanovic D,Bézieau S,Blackburn PR,Bunt J,Burglen L,Campeau PM,Charles P,Chung BHY,Cogné B,Curry C,D'Agostino MD,Di Donato N,Faivre L,Héron D,Innes AM,Isidor B,Keren B,Kimball A,Klee EW,Kuentz P,Küry S,Martin-Coignard D,Mirzaa G,Mignot C,Miyake N,Matsumoto N,Fujita A,Nava C,Nizon M,Rodriguez D,Blok LS,Thauvin-Robinet C,Thevenon J,Vincent M,Ziegler A,Dobyns W,Richards LJ,Barkovich AJ,Floor SN,Silver DL,Sherr EH
14-9965-80 was used in Immunohistochemistry (Frozen) to elucidate mechanisms by which pathogenic DDX3X variants disrupt brain development, using human and mouse genetics and cell biological and biochemical approaches.
Wed May 06 00:00:00 EDT 2020
Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching.
Developmental cell
Young RE,Jones MK,Hines EA,Li R,Luo Y,Shi W,Verheyden JM,Sun X
14-9965 was used in Immunohistochemistry-immunofluorescence to test the model of airway smooth muscle promoting lung branching through peristalsis and pushing intraluminal fluid to branching tips in vivo by inactivating Myocardin, which prevented airway smooth muscle differentiation.
Mon Apr 06 00:00:00 EDT 2020
P73 C-terminus is dispensable for multiciliogenesis.
Cell cycle (Georgetown, Tex.)
Buckley N,Panatta E,Morone N,Noguchi M,Scorrano L,Knight RA,Amelio I,Melino G
14-9965-82 was used in Immunohistochemistry to indicate that C-terminus p73 is dispensable for the multiciliogenesis program and suggests a possible tissue-specific effect of p73 alternative splicing.
Wed Jul 01 00:00:00 EDT 2020
Creation of Laryngeal Grafts from Primary Human Cells and Decellularized Laryngeal Scaffolds.
Tissue engineering. Part A
Moser PT,Gerli M,Diercks GR,Evangelista-Leite D,Charest JM,Gershlak JR,Ren X,Gilpin SE,Jank BJ,Gaudette GR,Hartnick CJ,Ott HC
14-9965 was used in Immunohistochemistry to report the de novo formation of three humanized laryngeal tissue compartments under one uniform culture condition, a possible keystone in creating vital composite tissue grafts for laryngeal regeneration.
Fri May 01 00:00:00 EDT 2020
Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration.
Frontiers in pharmacology
Yuan T,Klinkhammer K,Lyu H,Gao S,Yuan J,Hopkins S,Zhang JS,De Langhe SP
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Mon Sep 28 00:00:00 EDT 2020
Chloride channels regulate differentiation and barrier functions of the mammalian airway.
eLife
He M,Wu B,Ye W,Le DD,Sinclair AW,Padovano V,Chen Y,Li KX,Sit R,Tan M,Caplan MJ,Neff N,Jan YN,Darmanis S,Jan LY
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Apr 14 00:00:00 EDT 2020
Chloride channels regulate differentiation and barrier functions of the mammalian airway.
eLife
He M,Wu B,Ye W,Le DD,Sinclair AW,Padovano V,Chen Y,Li KX,Sit R,Tan M,Caplan MJ,Neff N,Jan YN,Darmanis S,Jan LY
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunocytochemistry
Tue Apr 14 00:00:00 EDT 2020
Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD.
EBioMedicine
Belgacemi R,Luczka E,Ancel J,Diabasana Z,Perotin JM,Germain A,Lalun N,Birembaut P,Dubernard X,Mérol JC,Delepine G,Polette M,Deslée G,Dormoy V
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Western Blot
Wed Jan 01 00:00:00 EST 2020
Fallopian Tube Basal Stem Cells Reproducing the Epithelial Sheets In Vitro-Stem Cell of Fallopian Epithelium.
Biomolecules
Zhu M,Iwano T,Takeda S
14-9965 was used in Immunocytochemistry to optimise the culture condition for the stable expansion of basal stem cells, and inducing differentiation of basal cells into polarized secretory and ciliated cells in the air-liquid interface (ALI) condition that suitable for long-term culture.
Thu Sep 03 00:00:00 EDT 2020
Fallopian Tube Basal Stem Cells Reproducing the Epithelial Sheets In Vitro-Stem Cell of Fallopian Epithelium.
Biomolecules
Zhu M,Iwano T,Takeda S
14-9965 was used in Immunocytochemistry to optimise the culture condition for the stable expansion of basal stem cells, and inducing differentiation of basal cells into polarized secretory and ciliated cells in the air-liquid interface (ALI) condition that suitable for long-term culture.
Thu Sep 03 00:00:00 EDT 2020
Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.
Current protocols in stem cell biology
Leibel SL,McVicar RN,Winquist AM,Niles WD,Snyder EY
14-9965 was used in Immunocytochemistry-immunoflourescence to describe a system that allows human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) to differentiate and form three-dimensional (3D) structures that emulate the development, cytoarchitecture, and function of the lung ("organoids"), containing epithelial and mesenchymal cell populations, and including the production of surfactant and presence of ciliated cells.
Tue Sep 01 00:00:00 EDT 2020
Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch.
Cell
Ouadah Y,Rojas ER,Riordan DP,Capostagno S,Kuo CS,Krasnow MA
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to propose that neuroendocrine stem cells give rise to small cell lung cancer, and transformation results from constitutive activation of stem cell renewal and inhibition of deprogramming.
Thu Oct 03 00:00:00 EDT 2019
Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members.
Neuron
Ortiz-Álvarez G,Daclin M,Shihavuddin A,Lansade P,Fortoul A,Faucourt M,Clavreul S,Lalioti ME,Taraviras S,Hippenmeyer S,Livet J,Meunier A,Genovesio A,Spassky N
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Wed Apr 03 00:00:00 EDT 2019
Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.
The Journal of experimental medicine
Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon Sep 02 00:00:00 EDT 2019
Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.
The Journal of experimental medicine
Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon Sep 02 00:00:00 EDT 2019
Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.
PLoS pathogens
Fiege JK,Stone IA,Dumm RE,Waring BM,Fife BT,Agudo J,Brown BD,Heaton NS,Langlois RA
14-9965 was used in Immunocytochemistry-immunoflourescence to demonstrate that ciliated epithelial cells, type I and type II alveolar cells can survive influenza A virus (IAV) infection and that these cells robustly proliferate and are stable long term.
Sun Sep 01 00:00:00 EDT 2019
E3 ubiquitin ligase MDM2 acts through p53 to control respiratory progenitor cell number and lung size.
Development (Cambridge, England)
Sui P,Li R,Zhang Y,Tan C,Garg A,Verheyden JM,Sun X
14-9965 was used in Immunohistochemistry to demonstrate that p53 protein turnover by MDM2, which encodes an E3 ubiquitin ligase, is essential for the survival of respiratory progenitors (a key determinant factor for final lung size).
Mon Dec 16 00:00:00 EST 2019
A Subset of Olfactory Sensory Neurons Express Forkhead Box J1-Driven eGFP.
Chemical senses
Larson ED,Pathak S,Ramakrishnan VR,Finger TE
14-9965 was used in Immunohistochemistry-immunofluorescence to suggest that Foxj1-driven eGFP marks a specific population of olfactory and vomeronasal sensory neurons, although neither receptor cell population possess motile cilia.
Sat Oct 26 00:00:00 EDT 2019
Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.
Developmental biology
Liberti DC,Zepp JA,Bartoni CA,Liberti KH,Zhou S,Lu M,Morley MP,Morrisey EE
14-9965-82 was used in Immunohistochemistry to demonstrate that DNA methyltransferase 1 (Dnmt1) is required for early branching morphogenesis of the lungs and for restraining epithelial fate specification.
Tue Oct 15 00:00:00 EDT 2019
Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.
eLife
Stupnikov MR,Yang Y,Mori M,Lu J,Cardoso WV
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon Oct 21 00:00:00 EDT 2019
Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.
eLife
Stupnikov MR,Yang Y,Mori M,Lu J,Cardoso WV
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon Oct 21 00:00:00 EDT 2019
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function.
Nature communications
Dumm RE,Fiege JK,Waring BM,Kuo CT,Langlois RA,Heaton NS
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Fri Feb 15 00:00:00 EST 2019
STK11 is required for the normal program of ciliated cell differentiation in airways.
Cell discovery
Chu Q,Yao C,Qi X,Stripp BR,Tang N
14-9965 was used in Immunohistochemistry to establish that multiciliogenesis and ciliated cell fate commitment is regulated by the STK11/MARK3/ERK1/2 signaling cascade.
Wed Sep 30 00:00:00 EDT 2020
STK11 is required for the normal program of ciliated cell differentiation in airways.
Cell discovery
Chu Q,Yao C,Qi X,Stripp BR,Tang N
14-9965 was used in Immunohistochemistry to establish that multiciliogenesis and ciliated cell fate commitment is regulated by the STK11/MARK3/ERK1/2 signaling cascade.
Wed Sep 30 00:00:00 EDT 2020
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Developmental cell
Tata PR,Chow RD,Saladi SV,Tata A,Konkimalla A,Bara A,Montoro D,Hariri LP,Shih AR,Mino-Kenudson M,Mou H,Kimura S,Ellisen LW,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon Mar 26 00:00:00 EDT 2018
Characterization of the ventricular-subventricular stem cell niche during human brain development.
Development (Cambridge, England)
Coletti AM,Singh D,Kumar S,Shafin TN,Briody PJ,Babbitt BF,Pan D,Norton ES,Brown EC,Kahle KT,Del Bigio MR,Conover JC
14-9965 was used in Immunohistochemistry to reveal normal human V-SVZ development, highlighting the consequence of disease pathologies such as congenital hydrocephalus.
Fri Oct 26 00:00:00 EDT 2018
Expansion of Airway Basal Cells and Generation of Polarized Epithelium.
Bio-protocol
Levardon H,Yonker LM,Hurley BP,Mou H
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Tue Jun 05 00:00:00 EDT 2018
Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells.
Scientific reports
Hedström U,Hallgren O,Öberg L,DeMicco A,Vaarala O,Westergren-Thorsson G,Zhou X
14-9965 was used in Immunohistochemistry to show that bronchial ECM from COPD patients induces differential gene expression in primary NHBE cells when compared to normal bronchial ECM.
Thu Feb 22 00:00:00 EST 2018
CDC20B is required for deuterosome-mediated centriole production in multiciliated cells.
Nature communications
Revinski DR,Zaragosi LE,Boutin C,Ruiz-Garcia S,Deprez M,Thomé V,Rosnet O,Gay AS,Mercey O,Paquet A,Pons N,Ponzio G,Marcet B,Kodjabachian L,Barbry P
14-9965 was used in Immunohistochemistry-immunofluorescence to investigate the cell division cycle 20B gene in multiciliated cells.
Wed Nov 07 00:00:00 EST 2018
Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.
Cell
Van Dyken SJ,Liang HE,Naikawadi RP,Woodruff PG,Wolters PJ,Erle DJ,Locksley RM
14-9965 was used in Immunohistochemistry to show that altered chitin clearance could exacerbate fibrogenic pathways in the setting of lung diseases characterised by epithelial cell dysfunction.
Thu Apr 20 00:00:00 EDT 2017
Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.
Proceedings of the National Academy of Sciences of the United States of America
Otto T,Candido SV,Pilarz MS,Sicinska E,Bronson RT,Bowden M,Lachowicz IA,Mulry K,Fassl A,Han RC,Jecrois ES,Sicinski P
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Tue Oct 03 00:00:00 EDT 2017
Forkhead Box Protein J1 (FOXJ1) is Overexpressed in Colorectal Cancer and Promotes Nuclear Translocation of β-Catenin in SW620 Cells.
Medical science monitor : international medical journal of experimental and clinical research
Liu K,Fan J,Wu J
14-9965 was used in Western Blotting to demonstrate that increased FOXJ1 contributes to the progression of colorectal cancer.
Fri Feb 17 00:00:00 EST 2017
The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis.
PloS one
Muniz-Talavera H,Schmidt JV
14-9965 was used in Immunohistochemistry-immunofluorescence to show that JHY does not only control ciliogenesis, but is a crucial component of the ependymal differentiation process.
Wed Jan 10 00:00:00 EST 2018
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.
eLife
Nikolić MZ,Caritg O,Jeng Q,Johnson JA,Sun D,Howell KJ,Brady JL,Laresgoiti U,Allen G,Butler R,Zilbauer M,Giangreco A,Rawlins EL
14-9965-82 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Frozen) to investigate human pluripotent stem cell differentiation to lung epithelium.
Fri Jun 30 00:00:00 EDT 2017
Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.
Nature cell biology
Li L,Grausam KB,Wang J,Lun MP,Ohli J,Lidov HG,Calicchio ML,Zeng E,Salisbury JL,Wechsler-Reya RJ,Lehtinen MK,Schüller U,Zhao H
14-9965 was used in Immunofluorescence to demonstrate that abnormal SHH signaling and distinct ciliogenesis are detected in human choroid plexus tumours.
Fri Apr 01 00:00:00 EDT 2016
Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.
Cell stem cell
Mou H,Vinarsky V,Tata PR,Brazauskas K,Choi SH,Crooke AK,Zhang B,Solomon GM,Turner B,Bihler H,Harrington J,Lapey A,Channick C,Keyes C,Freund A,Artandi S,Mense M,Rowe S,Engelhardt JF,Hsu YC,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Thu Aug 04 00:00:00 EDT 2016
GEMC1 is a critical regulator of multiciliated cell differentiation.
The EMBO journal
Terré B,Piergiovanni G,Segura-Bayona S,Gil-Gómez G,Youssef SA,Attolini CS,Wilsch-Bräuninger M,Jung C,Rojas AM,Marjanović M,Knobel PA,Palenzuela L,López-Rovira T,Forrow S,Huttner WB,Valverde MA,de Bruin A,Costanzo V,Stracker TH
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Mon May 02 00:00:00 EDT 2016
An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.
Developmental cell
Balasooriya GI,Johnson JA,Basson MA,Rawlins EL
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2016
An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.
Developmental cell
Balasooriya GI,Johnson JA,Basson MA,Rawlins EL
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2016
An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.
Developmental cell
Balasooriya GI,Johnson JA,Basson MA,Rawlins EL
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2016
KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer.
Cell death and differentiation
Yu T,Chen X,Zhang W,Liu J,Avdiushko R,Napier DL,Liu AX,Neltner JM,Wang C,Cohen D,Liu C
14-9965 was used in Immunohistochemistry to suggesting that KLF4 is repressed by histone acetylation and that HDACs are valuable drug targets for lung cancer treatment.
Mon Feb 01 00:00:00 EST 2016
An in vitro model of murine middle ear epithelium.
Disease models & mechanisms
Mulay A,Akram KM,Williams D,Armes H,Russell C,Hood D,Armstrong S,Stewart JP,Brown SD,Bingle L,Bingle CD
14996582 was used in immunocytochemistry to design a model of mouse middle ear epithelial cells that recapitulates the characteristics of the native murine middle ear epithelium
Tue Nov 01 00:00:00 EDT 2016
Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection.
Stem cell reports
Ray S,Chiba N,Yao C,Guan X,McConnell AM,Brockway B,Que L,McQualter JL,Stripp BR
14996582 was used in immunohistochemistry - paraffin section to characterize the cellular dynamics of lung repair following influenza infection especially keratin 5 positive cells
Tue Nov 08 00:00:00 EST 2016
A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids.
eLife
Dye BR,Dedhia PH,Miller AJ,Nagy MS,White ES,Shea LD,Spence JR
14996582 was used in immunohistochemistry to find that human lung organoids require a bioartificial microporous poly(lactide-co-glycolide) scaffold niche for successful engraftment, long-term survival, and maturation of lung epithelium in vivo
Wed Sep 28 00:00:00 EDT 2016
Zbtb20 promotes astrocytogenesis during neocortical development.
Nature communications
Nagao M,Ogata T,Sawada Y,Gotoh Y
14-9965 was used in Immunocytochemistry to show that Zbtb20 regulates astrocyte specification in the mouse neocortex.
Tue Mar 22 00:00:00 EDT 2016
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations.
Cell stem cell
Pardo-Saganta A,Law BM,Tata PR,Villoria J,Saez B,Mou H,Zhao R,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Thu Feb 05 00:00:00 EST 2015
The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
Nature protocols
Huang SX,Green MD,de Carvalho AT,Mumau M,Chen YW,D'Souza SL,Snoeck HW
14-9965 was used in Immunofluorescence to describe a strategy for directed differentiation of hPSCs into developmental lung progenitors, and their subsequent differentiation into predominantly distal lung epithelial cells.
Sun Mar 01 00:00:00 EST 2015
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells.
The Journal of cell biology
Gao X,Bali AS,Randell SH,Hogan BL
Mon Nov 09 00:00:00 EST 2015
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells.
The Journal of cell biology
Gao X,Bali AS,Randell SH,Hogan BL
Mon Nov 09 00:00:00 EST 2015
Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung.
Development (Cambridge, England)
Galvis LA,Holik AZ,Short KM,Pasquet J,Lun AT,Blewitt ME,Smyth IM,Ritchie ME,Asselin-Labat ML
14-9965 was used in Immunohistochemistry-immunofluorescence to explore the role of the histone methyltransferase Ezh2 during lung lineage determination.
Wed Apr 15 00:00:00 EDT 2015
Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ohata S,Herranz-Pérez V,Nakatani J,Boletta A,García-Verdugo JM,Álvarez-Buylla A
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Wed Aug 05 00:00:00 EDT 2015
Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ohata S,Herranz-Pérez V,Nakatani J,Boletta A,García-Verdugo JM,Álvarez-Buylla A
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Wed Aug 05 00:00:00 EDT 2015
Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain.
Frontiers in cell and developmental biology
Cuevas E,Rybak-Wolf A,Rohde AM,Nguyen DT,Wulczyn FG
14-9965 was used in Immunocytochemistry to reveal that Lin41 is expressed in terminally differentiated ependymal cells of the brain.
Fri Apr 17 00:00:00 EDT 2015
The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression.
Respiratory research
Holik AZ,Filby CE,Pasquet J,Viitaniemi K,Ciciulla J,Sutherland KD,Asselin-Labat ML
14-9965 was used in Immunohistochemistry to show that Lmo4 participates in, but is not essential for, the regulation of lung epithelial cell proliferation.
Sun Jun 07 00:00:00 EDT 2015
The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression.
Respiratory research
Holik AZ,Filby CE,Pasquet J,Viitaniemi K,Ciciulla J,Sutherland KD,Asselin-Labat ML
14-9965 was used in Immunohistochemistry to show that Lmo4 participates in, but is not essential for, the regulation of lung epithelial cell proliferation.
Sun Jun 07 00:00:00 EDT 2015
Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
Nature biotechnology
Huang SX,Islam MN,O'Neill J,Hu Z,Yang YG,Chen YW,Mumau M,Green MD,Vunjak-Novakovic G,Bhattacharya J,Snoeck HW
14-9965 was used in Immunofluorescence to exhibit a highly efficient method for the directed differentiation of human pluripotent stem cells.
Wed Jan 01 00:00:00 EST 2014
Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.
Neuron
Ohata S,Nakatani J,Herranz-Pérez V,Cheng J,Belinson H,Inubushi T,Snider WD,García-Verdugo JM,Wynshaw-Boris A,Alvarez-Buylla A
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunohistochemistry
Wed Aug 06 00:00:00 EDT 2014
The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.
Genes & development
Xu X,Huang L,Futtner C,Schwab B,Rampersad RR,Lu Y,Sporn TA,Hogan BL,Onaitis MW
Mon Sep 01 00:00:00 EDT 2014
Dedifferentiation of committed epithelial cells into stem cells in vivo.
Nature
Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Thu Nov 14 00:00:00 EST 2013
Dedifferentiation of committed epithelial cells into stem cells in vivo.
Nature
Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Thu Nov 14 00:00:00 EST 2013
Dedifferentiation of committed epithelial cells into stem cells in vivo.
Nature
Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Thu Nov 14 00:00:00 EST 2013
The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.
American journal of physiology. Lung cellular and molecular physiology
Matsuo M,Shimada A,Koshida S,Saga Y,Takeda H
14-9965 was used in Immunohistochemistry to demonstrate the involvement of ciliary motility in the establishment of coordinated ciliary alignment varies among tissues.
Sat Jun 01 00:00:00 EDT 2013
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Respiratory research
Walters MS,Gomi K,Ashbridge B,Moore MA,Arbelaez V,Heldrich J,Ding BS,Rafii S,Staudt MR,Crystal RG
14-9965 was used in Western Blotting to develop an immortalized human airway basal cell (BC) line to further BC research and evaluate their use as a drug target.
Tue Dec 03 00:00:00 EST 2013
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Respiratory research
Walters MS,Gomi K,Ashbridge B,Moore MA,Arbelaez V,Heldrich J,Ding BS,Rafii S,Staudt MR,Crystal RG
14-9965 was used in Western Blotting to develop an immortalized human airway basal cell (BC) line to further BC research and evaluate their use as a drug target.
Tue Dec 03 00:00:00 EST 2013
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.
Cell stem cell
Mou H,Zhao R,Sherwood R,Ahfeldt T,Lapey A,Wain J,Sicilian L,Izvolsky K,Musunuru K,Cowan C,Rajagopal J
Published figure using FOXJ1 monoclonal antibody (Product # 14-9965-82) in Immunofluorescence
Fri Apr 06 00:00:00 EDT 2012
Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America
Xu X,Rock JR,Lu Y,Futtner C,Schwab B,Guinney J,Hogan BL,Onaitis MW
14-9965 was used in Immunohistochemistry-immunofluorescence to study the effect of induced expression of K-RasG12D in CC10(+) epithelial cells and Sftpc(+) type II alveolar cells of the adult mouse lung in lung hyperplasia.
Tue Mar 27 00:00:00 EDT 2012
Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.
Stem cells (Dayton, Ohio)
Chen H,Matsumoto K,Brockway BL,Rackley CR,Liang J,Lee JH,Jiang D,Noble PW,Randell SH,Kim CF,Stripp BR
14-9965 was used in Immunohistochemistry on paraffin embedded tissues to reveal intrinsic differences regional progenitor properties and suggest that their unique responses to tissue damage drive local tissue remodeling.
Sat Sep 01 00:00:00 EDT 2012
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.jpg?time=20240507?time=20240507 "FOXJ1 Antibody (14-9965-82) in IHC (P)")
