Product References
"Pulsed Hypoxia" Gradually Reprograms Breast Cancer Fibroblasts into Pro-Tumorigenic Cells via Mesenchymal-Epithelial Transition.
International journal of molecular sciences
Nushtaeva A,Ermakov M,Abdurakhmanova M,Troitskaya O,Belovezhets T,Varlamov M,Gayner T,Richter V,Koval O
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show consistent up-regulation of TWIST1 gene as an early response and ZEB1/2 and SLUG transcriptional activity as a subsequent response.
Fri Jan 27 00:00:00 EST 2023
"Pulsed Hypoxia" Gradually Reprograms Breast Cancer Fibroblasts into Pro-Tumorigenic Cells via Mesenchymal-Epithelial Transition.
International journal of molecular sciences
Nushtaeva A,Ermakov M,Abdurakhmanova M,Troitskaya O,Belovezhets T,Varlamov M,Gayner T,Richter V,Koval O
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show consistent up-regulation of TWIST1 gene as an early response and ZEB1/2 and SLUG transcriptional activity as a subsequent response.
Fri Jan 27 00:00:00 EST 2023
"Pulsed Hypoxia" Gradually Reprograms Breast Cancer Fibroblasts into Pro-Tumorigenic Cells via Mesenchymal-Epithelial Transition.
International journal of molecular sciences
Nushtaeva A,Ermakov M,Abdurakhmanova M,Troitskaya O,Belovezhets T,Varlamov M,Gayner T,Richter V,Koval O
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show consistent up-regulation of TWIST1 gene as an early response and ZEB1/2 and SLUG transcriptional activity as a subsequent response.
Fri Jan 27 00:00:00 EST 2023
Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.
Nature communications
Luo Z,Xin D,Liao Y,Berry K,Ogurek S,Zhang F,Zhang L,Zhao C,Rao R,Dong X,Li H,Yu J,Lin Y,Huang G,Xu L,Xin M,Nishinakamura R,Yu J,Kool M,Pfister SM,Roussel MF,Zhou W,Weiss WA,Andreassen P,Lu QR
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that CTDNEP1 is a tumor suppressor in highly aggressive MYC-driven medulloblastomas by controlling MYC activity and mitotic fidelity, pointing to a CTDNEP1-dependent targetable therapeutic vulnerability.
Fri Feb 10 00:00:00 EST 2023
MiRNA-106a-5p Promotes Laryngeal Carcinoma Proliferation and Migration Through PI3K/AKT/m-TOR Pathway by AKTIP.
Iranian journal of biotechnology
Gong L,Wang XF,Liu H,Li L
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to uncover a new mechanism, that miR-106a-5p promotes LC development via AKTIP/PI3K/AKT/m-TOR axis, which guides clinical management and drug discovery.
Sun Jan 01 00:00:00 EST 2023
Genetically engineered human pituitary corticotroph tumor organoids exhibit divergent responses to glucocorticoid receptor modulators.
Translational research : the journal of laboratory and clinical medicine
Mallick S,Chakrabarti J,Eschbacher J,Moraitis AG,Greenstein AE,Churko J,Pond KW,Livolsi A,Thorne CA,Little AS,Yuen KCJ,Zavros Y
39-8600 was used in Western Blotting to identify the potential therapeutic use of relacorilant in combination with somatostatin analogs and demonstrated the advantages of relacorilant over mifepristone, supporting its further development for use in the treatment of Cushing's disease patients.
Thu Jun 01 00:00:00 EDT 2023
An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets.
PLoS biology
Moskal N,Visanji NP,Gorbenko O,Narasimhan V,Tyrrell H,Nash J,Lewis PN,McQuibban GA
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that probucol-mediated LD dynamics changes may prime the cell for a more efficient mitophagic response to mitochondrial damage.
Wed Mar 01 00:00:00 EST 2023
Enhancement of LncRNA-HFRL expression induces cardiomyocyte inflammation, proliferation, and fibrosis via the sequestering of miR-149-5p-mediated collagen 22A inhibition.
Annals of translational medicine
Li X,Teng Y,Tian M,Qiu H,Zhao J,Gao Q,Zhang Y,Zhuang J,Chen J
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Sun May 01 00:00:00 EDT 2022
The cyclin dependent kinase inhibitor p21Cip1/Waf1 is a therapeutic target in high-risk neuroblastoma.
Frontiers in oncology
Sorteberg AL,Halipi V,Wickström M,Shirazi Fard S
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Sat Sep 24 00:00:00 EDT 2022
Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant.
iScience
Zhan X,Drummond-Main C,Greening D,Yao J,Chen SWR,Appendino JP,Au PYB,Turner RW
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that the ability for cannabidiol to reduce the effects of a pathogenic Kv7.2 variant supports its use as a potential therapeutic to reduce seizure activity.
Fri Oct 21 00:00:00 EDT 2022
MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions.
Molecular & cellular proteomics : MCP
Devoucoux M,Roques C,Lachance C,Lashgari A,Joly-Beauparlant C,Jacquet K,Alerasool N,Prudente A,Taipale M,Droit A,Lambert JP,Hussein SMI,Côté J
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to provide a complete detailed picture of human MRG proteins-associated protein complexes, which are essential to understand and correlate their diverse biological functions in chromatin-based nuclear processes.
Fri Jul 01 00:00:00 EDT 2022
Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death.
Cell death & disease
Saha S,Verma R,Kumar C,Kumar B,Dey AK,Surjit M,Mylavarapu SVS,Maiti TK
39-8600 was used in Western Blotting to provide evidence of PA-induced hepatocellular death mediated by deubiquitinase USP7 downregulation and subsequent mitotic catastrophe.
Wed Jun 22 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to reveal a novel mechanism of MSC allograft rejection mediated by CD4+ CTLs in injured liver, which provided new strategies for improving clinical performance of allo-MSCs in benefiting hepatic injury repair.
Thu Dec 01 00:00:00 EST 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to reveal a novel mechanism of MSC allograft rejection mediated by CD4+ CTLs in injured liver, which provided new strategies for improving clinical performance of allo-MSCs in benefiting hepatic injury repair.
Thu Dec 01 00:00:00 EST 2022
Sting Is Commonly and Differentially Expressed in T- and Nk-Cell but Not B-Cell Non-Hodgkin Lymphomas.
Cancers
Xagoraris I,Farrajota Neves da Silva P,Kokaraki G,Stathopoulou K,Wahlin B,Österborg A,Herold N,Ng SB,Medeiros LJ,Drakos E,Sander B,Rassidakis GZ
39-8600 was used in Western Blot to investigate the expression patterns of stimulator interferon genes in T-, natural killer, and B- cell non-hodgkin lymphomas.
Thu Feb 24 00:00:00 EST 2022
Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene.
Nucleic acids research
Kalinina M,Skvortsov D,Kalmykova S,Ivanov T,Dontsova O,Pervouchine DD
39-8600 was used in Western Blotting to demonstrate that splicing is coordinated both in time and in space over very long distances, and that the interaction of these components is mediated by RNA structure.
Mon Jan 11 00:00:00 EST 2021
Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene.
Nucleic acids research
Kalinina M,Skvortsov D,Kalmykova S,Ivanov T,Dontsova O,Pervouchine DD
39-8600 was used in Western Blotting to demonstrate that splicing is coordinated both in time and in space over very long distances, and that the interaction of these components is mediated by RNA structure.
Mon Jan 11 00:00:00 EST 2021
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.
Proceedings of the National Academy of Sciences of the United States of America
Kook S,Wang P,Meng S,Jetter CS,Sucre JMS,Benjamin JT,Gokey JJ,Hanby HA,Jaume A,Goetzl L,Marks MS,Guttentag SH
39-8600 was used in Immunohistochemistry to illuminate a mechanism whereby loss of AP-3-mediated trafficking contributes to a toxic gain-of-function that results in enhanced and sustained activation of a repair pathway associated with pulmonary fibrosis.
Tue May 18 00:00:00 EDT 2021
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.
Proceedings of the National Academy of Sciences of the United States of America
Kook S,Wang P,Meng S,Jetter CS,Sucre JMS,Benjamin JT,Gokey JJ,Hanby HA,Jaume A,Goetzl L,Marks MS,Guttentag SH
39-8600 was used in Immunohistochemistry to illuminate a mechanism whereby loss of AP-3-mediated trafficking contributes to a toxic gain-of-function that results in enhanced and sustained activation of a repair pathway associated with pulmonary fibrosis.
Tue May 18 00:00:00 EDT 2021
Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma.
Haematologica
Youssef Y,Karkhanis V,Chan WK,Jeney F,Canella A,Zhang X,Sloan S,Prouty A,Helmig-Mason J,Tsyba L,Hanel W,Zheng X,Zhang P,Chung JH,Lucas DM,Kauffman Z,Larkin K,Strohecker AM,Ozer HG,Lapalombella R,Zhou H,Xu-Monette ZY,Young KH,Han R,Nurmemmedov E,Nuovo G,Maddocks K,Byrd JC,Baiocchi RA,Alinari L
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Nov 01 00:00:00 EDT 2021
Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma.
Haematologica
Youssef Y,Karkhanis V,Chan WK,Jeney F,Canella A,Zhang X,Sloan S,Prouty A,Helmig-Mason J,Tsyba L,Hanel W,Zheng X,Zhang P,Chung JH,Lucas DM,Kauffman Z,Larkin K,Strohecker AM,Ozer HG,Lapalombella R,Zhou H,Xu-Monette ZY,Young KH,Han R,Nurmemmedov E,Nuovo G,Maddocks K,Byrd JC,Baiocchi RA,Alinari L
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Nov 01 00:00:00 EDT 2021
Testicular orphan receptor 4 (TR4) promotes papillary thyroid cancer invasion via activating circ-FNLA/miR-149-5p/MMP9 signaling.
Molecular therapy. Nucleic acids
Ouyang X,Feng L,Yao L,Xiao Y,Hu X,Zhang G,Liu G,Wang Z
39-8600 was used in Western Blot to investigate the oncogenic role of testicular orphan receptor 4 in papillary thyroid cancer development.
Fri Jun 04 00:00:00 EDT 2021
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors.
Archives of toxicology
Delp J,Cediel-Ulloa A,Suciu I,Kranaster P,van Vugt-Lussenburg BM,Munic Kos V,van der Stel W,Carta G,Bennekou SH,Jennings P,van de Water B,Forsby A,Leist M
39-8600 was used in Western Blot to suggest that the use of AOP:3 for hazard assessment has a number of caveats: (i) specific parkinsonian neurodegeneration cannot be easily predicted from assays of mitochondrial dysfunction; (ii) deriving a point-of-departure for risk assessment from early KE assays may overestimate toxicant potency.
Mon Feb 01 00:00:00 EST 2021
Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas.
Frontiers in cell and developmental biology
Luo Z,Dong X,Yu J,Xia Y,Berry KP,Rao R,Xu L,Xue P,Chen T,Lin Y,Yu J,Huang G,Li H,Zhou W,Lu QR
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Thu Jul 15 00:00:00 EDT 2021
Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas.
Frontiers in cell and developmental biology
Luo Z,Dong X,Yu J,Xia Y,Berry KP,Rao R,Xu L,Xue P,Chen T,Lin Y,Yu J,Huang G,Li H,Zhou W,Lu QR
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Thu Jul 15 00:00:00 EDT 2021
PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins.
Frontiers in cell and developmental biology
Savelyev NV,Shepelev NM,Lavrik OI,Rubtsova MP,Dontsova OA
39-8600 was used in Western Blotting to provide the evidence that poly(ADP-ribosyl)ation regulates telomerase complex assembly and activity, in turn regulating telomere length that may be useful for design and development of anticancer therapeutic approaches that are based on the inhibition of PARP1 and telomerase activities.
Tue Jun 08 00:00:00 EDT 2021
PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins.
Frontiers in cell and developmental biology
Savelyev NV,Shepelev NM,Lavrik OI,Rubtsova MP,Dontsova OA
39-8600 was used in Western Blotting to provide the evidence that poly(ADP-ribosyl)ation regulates telomerase complex assembly and activity, in turn regulating telomere length that may be useful for design and development of anticancer therapeutic approaches that are based on the inhibition of PARP1 and telomerase activities.
Tue Jun 08 00:00:00 EDT 2021
Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7.
Molecular and cellular biology
Zhao X,Dong W,Luo G,Xie J,Liu J,Yu F
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate circular RNAs and microRNAs influencing HoXB7 in cervical cancer.
Fri May 21 00:00:00 EDT 2021
Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7.
Molecular and cellular biology
Zhao X,Dong W,Luo G,Xie J,Liu J,Yu F
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate circular RNAs and microRNAs influencing HoXB7 in cervical cancer.
Fri May 21 00:00:00 EDT 2021
Long noncoding RNA POU6F2-AS1 regulates lung cancer aggressiveness through sponging miR-34c-5p to modulate KCNJ4 expression.
Genetics and molecular biology
Wu XY,Xie Y,Zhou LY,Zhao YY,Zhang J,Zhang XF,Guo S,Yu XY
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Aug 22 00:00:00 EDT 2022
Long noncoding RNA POU6F2-AS1 regulates lung cancer aggressiveness through sponging miR-34c-5p to modulate KCNJ4 expression.
Genetics and molecular biology
Wu XY,Xie Y,Zhou LY,Zhao YY,Zhang J,Zhang XF,Guo S,Yu XY
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Aug 22 00:00:00 EDT 2022
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Deng Q,Wu L,Li Y,Zou L
39-8600 was used in Western Blot to examine the role of myeloblastosis viral oncogene homolog-like 2 (MYBL2) in gastric cancer progression and investigate the underlying mechanisms.
Wed Sep 01 00:00:00 EDT 2021
Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.
Frontiers in physiology
Kabakov AY,Sengun E,Lu Y,Roder K,Bronk P,Baggett B,Turan NN,Moshal KS,Koren G
39-8600 was used in Western Blot to develop and characterize a novel low-cost rabbit cardiomyocyte model, namely, 3-week-old ventricular cardiomyocytes (3wRbCMs), for studying cardiac cell excitation and arrhythmogenicity.
Wed Mar 15 00:00:00 EDT 2023
Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.
Frontiers in physiology
Kabakov AY,Sengun E,Lu Y,Roder K,Bronk P,Baggett B,Turan NN,Moshal KS,Koren G
39-8600 was used in Western Blot to develop and characterize a novel low-cost rabbit cardiomyocyte model, namely, 3-week-old ventricular cardiomyocytes (3wRbCMs), for studying cardiac cell excitation and arrhythmogenicity.
Wed Mar 15 00:00:00 EDT 2023
Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML).
Biomedicines
Djamai H,Berrou J,Dupont M,Coudé MM,Delord M,Clappier E,Marceau-Renaut A,Kaci A,Raffoux E,Itzykson R,Berthier C,Wu HC,Hleihel R,Bazarbachi A,de Thé H,Baruchel A,Gardin C,Dombret H,Braun T
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Wed Nov 17 00:00:00 EST 2021
Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells.
Frontiers in genetics
Huang X,Shen W,Veizades S,Liang G,Sayed N,Nguyen PK
39-8600 was used in Western Blotting to perform an integrated characterization of the endothelial cell transcriptome of five major organs (e.g., fat, heart-aorta, lung, limb muscle, and kidney) isolated from male and female C57BL/6 mice at 3 and 18 months of age.
Wed Mar 10 00:00:00 EST 2021
Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6Chi/lo macrophages through activating the cytokine-paracrine and apoptotic pathways.
Cell death discovery
Li YH,Shen S,Shao T,Jin MT,Fan DD,Lin AF,Xiang LX,Shao JZ
39-8600 was used in Western Blot to provide insights into the functional role of bone marrow-derived sesenchymal stem cell in alleviating liver fibrosis.
Mon Sep 13 00:00:00 EDT 2021
Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death.
The Journal of cell biology
Dziengelewski C,Rodrigue MA,Caillier A,Jacquet K,Boulanger MC,Bergeman J,Fuchs M,Lambert H,Laprise P,Richard DE,Bordeleau F,Huot MÉ,Lavoie JN
39-8600 was used in Western Blotting to show that the tumoricidal effect of E4orf4 is typified by changes in nuclear dynamics that depend on its interaction with the polarity protein Par3 and actomyosin contractility.
Mon Apr 06 00:00:00 EDT 2020
Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death.
The Journal of cell biology
Dziengelewski C,Rodrigue MA,Caillier A,Jacquet K,Boulanger MC,Bergeman J,Fuchs M,Lambert H,Laprise P,Richard DE,Bordeleau F,Huot MÉ,Lavoie JN
39-8600 was used in Western Blotting to show that the tumoricidal effect of E4orf4 is typified by changes in nuclear dynamics that depend on its interaction with the polarity protein Par3 and actomyosin contractility.
Mon Apr 06 00:00:00 EDT 2020
Astrocytic Ephrin-B1 Controls Excitatory-Inhibitory Balance in Developing Hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nguyen AQ,Sutley S,Koeppen J,Mina K,Woodruff S,Hanna S,Vengala A,Hickmott PW,Obenaus A,Ethell IM
39-8600 was used in Western Blotting to examine whether the loss or overexpression of the membrane-bound ephrin-B1 in astrocytes during postnatal day 14-28 period would affect synapse formation and maturation in the developing hippocampus.
Wed Sep 02 00:00:00 EDT 2020
Butyrate Reprograms Expression of Specific Interferon-Stimulated Genes.
Journal of virology
Chemudupati M,Kenney AD,Smith AC,Fillinger RJ,Zhang L,Zani A,Liu SL,Anderson MZ,Sharma A,Yount JS
39-8600 was used in Western Blotting to report a previously unknown role for butyrate in transcriptionally reprogramming the type I IFN response.
Thu Jul 30 00:00:00 EDT 2020
Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression.
EXCLI journal
Lima KG,Schneider Levorse VG,Rosa Garcia MC,de Souza Basso B,Pasqualotto Costa B,Antunes GL,Luft C,Haute GV,Leal Xavier L,Donadio MVF,Rodrigues de Oliveira J
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Sun Jan 10 00:00:00 EST 2021
Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.
Frontiers in synaptic neuroscience
Nguyen AQ,Koeppen J,Woodruff S,Mina K,Figueroa Z,Ethell IM
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Sep 28 00:00:00 EDT 2020
Silencing of soluble epoxide hydrolase 2 gene reduces H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells via activating PI3K/Akt/GSK3β signaling pathway.
Cytotechnology
Li J,Luo J,Zhang Y,Tang C,Wang J,Chen C
39-8600 was used in Western Blotting to explore the effects and molecular mechanism of siEPHX2 on H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells.
Sat Feb 01 00:00:00 EST 2020
Antifungal itraconazole ameliorates experimental autoimmune encephalomyelitis through a novel mechanism of action.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Huang H,Tian X,Peng X,Huang L,Mei L,Zhan Y,Chen S,Wu H,Wei G,Cai X
39-8600 was used in Western Blotting to reveal a new method for treating MS using currently approved antifungal drugs.
Fri May 01 00:00:00 EDT 2020
Differences in HBV Replication, APOBEC3 Family Expression, and Inflammatory Cytokine Levels Between Wild-Type HBV and Pre-core (G1896A) or Basal Core Promoter (A1762T/G1764A) Mutants.
Frontiers in microbiology
Lau KCK,Joshi SS,Mahoney DJ,Mason AL,van Marle G,Osiowy C,Coffin CS
39-8600 was used in Western Blotting to the molecular biological basis of chronic hepatitis B virus variants, particularly the G1896A pre-core (PC) and A1762T/G1764A basal core promoter (BCP) mutations contributing risk factors for cirrhosis and hepatocellular carcinoma.
Sat Apr 16 00:00:00 EDT 2022
Differences in HBV Replication, APOBEC3 Family Expression, and Inflammatory Cytokine Levels Between Wild-Type HBV and Pre-core (G1896A) or Basal Core Promoter (A1762T/G1764A) Mutants.
Frontiers in microbiology
Lau KCK,Joshi SS,Mahoney DJ,Mason AL,van Marle G,Osiowy C,Coffin CS
39-8600 was used in Western Blotting to the molecular biological basis of chronic hepatitis B virus variants, particularly the G1896A pre-core (PC) and A1762T/G1764A basal core promoter (BCP) mutations contributing risk factors for cirrhosis and hepatocellular carcinoma.
Sat Apr 16 00:00:00 EDT 2022
Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights.
Cancers
Povo-Retana A,Mojena M,Stremtan AB,Fernández-García VB,Gómez-Sáez A,Nuevo-Tapioles C,Molina-Guijarro JM,Avendaño-Ortiz J,Cuezva JM,López-Collazo E,Martínez-Leal JF,Boscá L
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Tue Oct 20 00:00:00 EDT 2020
Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
Cell reports
Zhang H,Devoucoux M,Song X,Li L,Ayaz G,Cheng H,Tempel W,Dong C,Loppnau P,Côté J,Min J
39-8600 was used in Western Blotting to provide a structural framework for understanding the mechanism by which MBTD1 recruits the NuA4/TIP60 acetyltransferase complex to influence transcription and DNA repair pathway choice.
Tue Mar 24 00:00:00 EDT 2020
Computational-based discovery of FAK FERM domain chemical probes that inhibit HER2-FAK cancer signaling.
Chemical biology & drug design
Stahl E,Nott R,Koessel K,Cance W,Marlowe T
39-8600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify two new probes that target FAK FERM, enabling future investigation of this domain.
Mon Jun 01 00:00:00 EDT 2020
Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability.
Cancers
Díaz-Díaz A,Roca-Lema D,Casas-Pais A,Romay G,Colombo G,Concha Á,Graña B,Figueroa A
39-8600 was used in Western Blot to identify Hakai as a novel Hsp90 client protein and shed light on the regulation of Hakai stability.
Wed Jan 15 00:00:00 EST 2020
The lipidated connexin mimetic peptide SRPTEKT-Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform.
American journal of physiology. Cell physiology
Cotter ML,Boitano S,Lampe PD,Solan JL,Vagner J,Ek-Vitorin JF,Burt JM
39-8600 was used in Western Blot to indicate that SRPTEKT-Hdc is a potent inhibitor of physiological Ca2+-wave signaling mediated specifically by the pS368 phosphorylated form of Cx43.
Tue Oct 01 00:00:00 EDT 2019
A SUMOylation-dependent switch of RAB7 governs intracellular life and pathogenesis of Salmonella Typhimurium.
Journal of cell science
Mohapatra G,Gaur P,Mujagond P,Singh M,Rana S,Pratap S,Kaur N,Verma S,Krishnan V,Singh N,Srikanth CV
39-8600 was used in Western Blotting to study the role of SUMOylation in salmonella-containing vacuole biology.
Fri Jan 11 00:00:00 EST 2019
SPINT2 (HAI-2) missense variants identified in congenital sodium diarrhea/tufting enteropathy affect the ability of HAI-2 to inhibit prostasin but not matriptase.
Human molecular genetics
Holt-Danborg L,Vodopiutz J,Nonboe AW,De Laffolie J,Skovbjerg S,Wolters VM,Müller T,Hetzer B,Querfurt A,Zimmer KP,Jensen JK,Entenmann A,Heinz-Erian P,Vogel LK,Janecke AR
39-8600 was used in Western Blot to report three novel SCSD patients, two novel SPINT2 mutations and review published cases.
Fri Mar 01 00:00:00 EST 2019
Allergic sensitization increases the amount of extracellular ATP hydrolyzed by guinea pig leukocytes.
Purinergic signalling
Chávez J,Vargas MH,Martínez-Zúñiga J,Falfán-Valencia R,Ambrocio-Ortiz E,Carbajal V,Sandoval-Roldán R
39-8600 was used in Western Blotting to conclude that allergic sensitization increased the amount of ATP hydrolyzed by ectonucleotidases.
Fri Mar 01 00:00:00 EST 2019
Interleukin-8 blockade prevents activated endothelial cell mediated proliferation and chemoresistance of acute myeloid leukemia.
Leukemia research
Vijay V,Miller R,Vue GS,Pezeshkian MB,Maywood M,Ast AM,Drusbosky LM,Pompeu Y,Salgado AD,Lipten SD,Geddes T,Blenc AM,Ge Y,Ostrov DA,Cogle CR,Madlambayan GJ
39-8600 was used in Western Blot to show mechanistically that AML-induced endothelial cell activation induces the secretion of interleukin-8 (IL-8) leading to significant expansion of non-adherent AML cells and resistance to cytarabine (Ara-C) and demonstrate a new therapeutic strategy for targeting the sanctuary of an activated leukemia microenvironment.
Sun Sep 01 00:00:00 EDT 2019
Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells.
International journal of ophthalmology
Che ST,Bie L,Li X,Qi H,Yu P,Zuo L
39-8600 was used in Western Blotting to deduce that human uveal melanoma cell proliferation can be inhibited and apoptosis induced by parthenolide through the arrest of G1 phase and regulation of the mitochondrial pathway.
Thu Oct 01 00:00:00 EDT 2020
Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins.
Scientific reports
Wang X,Williams D,Müller I,Lemieux M,Dukart R,Maia IBL,Wang H,Woerman AL,Schmitt-Ulms G
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Thu Nov 07 00:00:00 EST 2019
Improved efficacy of a next-generation ERT in murine Pompe disease.
JCI insight
Xu S,Lun Y,Frascella M,Garcia A,Soska R,Nair A,Ponery AS,Schilling A,Feng J,Tuske S,Valle MCD,Martina JA,Ralston E,Gotschall R,Valenzano KJ,Puertollano R,Do HV,Raben N,Khanna R
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Thu Mar 07 00:00:00 EST 2019
In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells.
International journal of medical sciences
Roca-Lema D,Martinez-Iglesias O,Fernández de Ana Portela C,Rodríguez-Blanco A,Valladares-Ayerbes M,Díaz-Díaz A,Casas-Pais A,Prego C,Figueroa A
39-8600 was used in Western Blotting to evaluate the anticancer effects of polysaccharide-rich extracts from Trametes Versicolor and Grifola Frondosa in colon cancer cells.
Wed Jun 05 00:00:00 EDT 2019
Interferon-induced transmembrane proteins inhibit cell fusion mediated by trophoblast syncytins.
The Journal of biological chemistry
Zani A,Zhang L,McMichael TM,Kenney AD,Chemudupati M,Kwiek JJ,Liu SL,Yount JS
39-8600 was used in Western Blotting to indicate that IFN-induced transmembrane proteins inhibit trophoblast fusion, suggesting a critical balance between their antifusogenic and antiviral effects during pregnancy.
Fri Dec 27 00:00:00 EST 2019
Protein encoded in human telomerase RNA is involved in cell protective pathways.
Nucleic acids research
Rubtsova M,Naraykina Y,Vasilkova D,Meerson M,Zvereva M,Prassolov V,Lazarev V,Manuvera V,Kovalchuk S,Anikanov N,Butenko I,Pobeguts O,Govorun V,Dontsova O
39-8600 was used in Western Blotting to identify hTERP and study its cellular role.
Fri Sep 28 00:00:00 EDT 2018
High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway.
Acta pharmaceutica Sinica. B
Yuliantie E,Dai X,Yang D,Crack PJ,Wang MW
39-8600 was used in Western Blotting to perform a high-throughput screen for small molecule inhibitors of the type-I interferon signalling pathway.
Mon Oct 01 00:00:00 EDT 2018
Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Koeppen J,Nguyen AQ,Nikolakopoulou AM,Garcia M,Hanna S,Woodruff S,Figueroa Z,Obenaus A,Ethell IM
39-8600 was used in Western Blotting to examine the role of astrocytic ephrin-B1 as a regulator of synaptogenesis in the murine adult hippocampus and learning behaviours.
Wed Jun 20 00:00:00 EDT 2018
Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Koeppen J,Nguyen AQ,Nikolakopoulou AM,Garcia M,Hanna S,Woodruff S,Figueroa Z,Obenaus A,Ethell IM
39-8600 was used in Western Blotting to examine the role of astrocytic ephrin-B1 as a regulator of synaptogenesis in the murine adult hippocampus and learning behaviours.
Wed Jun 20 00:00:00 EDT 2018
MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs.
RNA (New York, N.Y.)
Kurata JS,Lin RJ
39-8600 was used in Western Blotting to show the LX-miR library is useful for genome-wide unbiased screening to identify miRNAs important for cellular fitness and likely to be useful for other functional screens.
Sun Jul 01 00:00:00 EDT 2018
Forkhead box C2 promotes the invasion ability of human trophoblast cells through Hedgehog (Hh) signaling pathway.
Cell biology international
Zhang Y,Zhang Y
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Sun Jul 01 00:00:00 EDT 2018
Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth.
EBioMedicine
Kock A,Larsson K,Bergqvist F,Eissler N,Elfman LHM,Raouf J,Korotkova M,Johnsen JI,Jakobsson PJ,Kogner P
39-8600 was used in Western Blotting to provide proof-of-principle of the benefits of targeting microsomal prostaglandin E synthase-1 in neuroblastoma.
Fri Jun 01 00:00:00 EDT 2018
Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation.
Oncoimmunology
Adam I,Dewi DL,Mooiweer J,Sadik A,Mohapatra SR,Berdel B,Keil M,Sonner JK,Thedieck K,Rose AJ,Platten M,Heiland I,Trump S,Opitz CA
39-8600 was used in Western Blotting to elucidate the importance of WARS upregulation in the prevention of excessive tryptophan depletion in tryptophan-degrading cancer cells.
Tue Jan 12 00:00:00 EST 2021
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Nature medicine
Herold N,Rudd SG,Ljungblad L,Sanjiv K,Myrberg IH,Paulin CB,Heshmati Y,Hagenkort A,Kutzner J,Page BD,Calderón-Montaño JM,Loseva O,Jemth AS,Bulli L,Axelsson H,Tesi B,Valerie NC,Höglund A,Bladh J,Wiita E,Sundin M,Uhlin M,Rassidakis G,Heyman M,Tamm KP,Warpman-Berglund U,Walfridsson J,Lehmann S,Grandér D,Lundbäck T,Kogner P,Henter JI,Helleday T,Schaller T
398600 was used in western blot to show that the deoxynucleoside triphosphate triphosphohydrolase SAM domain and HD domain 1 promotes the detoxification of intracellular cytostatic deoxycytidine analog cytarabine triphosphate pools
Wed Feb 01 00:00:00 EST 2017
IFITM3 requires an amphipathic helix for antiviral activity.
EMBO reports
Chesarino NM,Compton AA,McMichael TM,Kenney AD,Zhang L,Soewarna V,Davis M,Schwartz O,Yount JS
39-8600 was used in Western Blotting to identify the mechanism by which Interferon-induced transmembrane protein 3 blocks virus fusion with cell membranes.
Sun Oct 01 00:00:00 EDT 2017
Dexamethasone-loaded Polymeric Nanoconstructs for Monitoring and Treating Inflammatory Bowel Disease.
Theranostics
Lee A,De Mei C,Fereira M,Marotta R,Yoon HY,Kim K,Kwon IC,Decuzzi P
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Jun 25 00:00:00 EDT 2018
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.
The Journal of biological chemistry
Irimia JM,Meyer CM,Segvich DM,Surendran S,DePaoli-Roach AA,Morral N,Roach PJ
39-8600 was used in Western Blotting to investigate how the lack of liver glycogen increases fat accumulation and the development of liver insulin resistance.
Fri Jun 23 00:00:00 EDT 2017
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.
The Journal of biological chemistry
Irimia JM,Meyer CM,Segvich DM,Surendran S,DePaoli-Roach AA,Morral N,Roach PJ
39-8600 was used in Western Blotting to investigate how the lack of liver glycogen increases fat accumulation and the development of liver insulin resistance.
Fri Jun 23 00:00:00 EDT 2017
Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor.
Nature communications
Panda D,Saha P,Das T,Dash J
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Fri Jul 14 00:00:00 EDT 2017
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.
Oncoimmunology
Dewi DL,Mohapatra SR,Blanco Cabañes S,Adam I,Somarribas Patterson LF,Berdel B,Kahloon M,Thürmann L,Loth S,Heilmann K,Weichenhan D,Mücke O,Heiland I,Wimberger P,Kuhlmann JD,Kellner KH,Schott S,Plass C,Platten M,Gerhäuser C,Trump S,Opitz CA
39-8600 was used in Western Blotting to investigate the regulation of indoleamine-2,3-dioxygenase 1 in different breast cancer subtypes.
Tue Jan 12 00:00:00 EST 2021
Paracoccidioides brasiliensis induces recruitment of α3 and α5 integrins into epithelial cell membrane rafts, leading to cytokine secretion.
Microbes and infection
Barros BC,Maza PK,Alcantara C,Suzuki E
39-8600 was used in western blot to determine immune responses to Paracoccidioides brasiliensis
Fri Jan 01 00:00:00 EST 2016
Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.
Oncogene
Zhang J,Gao Q,Zhou Y,Dier U,Hempel N,Hochwald SN
39-8600 was used in western blot to test if FAK is an intrinsic driver that promotes aerobic glycolysis and tumorigenesis.
Thu Apr 14 00:00:00 EDT 2016
Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.
Oncogene
Zhang J,Gao Q,Zhou Y,Dier U,Hempel N,Hochwald SN
39-8600 was used in western blot to test if FAK is an intrinsic driver that promotes aerobic glycolysis and tumorigenesis.
Thu Apr 14 00:00:00 EDT 2016
Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.
Oncogene
Zhang J,Gao Q,Zhou Y,Dier U,Hempel N,Hochwald SN
39-8600 was used in western blot to test if FAK is an intrinsic driver that promotes aerobic glycolysis and tumorigenesis.
Thu Apr 14 00:00:00 EDT 2016
Airway Hyperresponsiveness in Asthma Model Occurs Independently of Secretion of β1 Integrins in Airway Wall and Focal Adhesions Proteins Down Regulation.
Journal of cellular biochemistry
Álvarez-Santos M,Carbajal V,Tellez-Jiménez O,Martínez-Cordero E,Ruiz V,Hernández-Pando R,Lascurain R,Santibañez-Salgado A,Bazan-Perkins B
39-8600 was used in western blot to assess the independence of secretion of beta-1 integrins in airway wall and focal adhesions proteins down regulation from airway hyperresponsiveness in asthma model
Sat Oct 01 00:00:00 EDT 2016
Histoplasma capsulatum-Induced Cytokine Secretion in Lung Epithelial Cells Is Dependent on Host Integrins, Src-Family Kinase Activation, and Membrane Raft Recruitment.
Frontiers in microbiology
Maza PK,Suzuki E
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Thu May 05 00:00:00 EDT 2016
Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases?
F1000Research
Ortuno D,Carlisle HJ,Miller S
39-8600 was used in western blot to study enhanced degradation of proteasomal substrates that are associated with neurodegenerative disease and the effect of inactivation of USP14
Mon May 09 00:00:00 EDT 2016
Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C.
BMC molecular biology
Skrdlant L,Stark JM,Lin RJ
39-8600 was used in western blot investigate the impact of serine-arginine rich splicing factor 2 mutations to myelodysplastic syndrome
Tue Aug 23 00:00:00 EDT 2016
Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.
The Journal of clinical investigation
Albrecht I,Wick C,Hallgren Å,Tjärnlund A,Nagaraju K,Andrade F,Thompson K,Coley W,Phadke A,Diaz-Gallo LM,Bottai M,Nennesmo I,Chemin K,Herrath J,Johansson K,Wikberg A,Ytterberg AJ,Zubarev RA,Danielsson O,Krystufkova O,Vencovsky J,Landegren N,Wahren-Herlenius M,Padyukov L,Kämpe O,Lundberg IE
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Tue Dec 01 00:00:00 EST 2015
E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3.
PLoS pathogens
Chesarino NM,McMichael TM,Yount JS
39-8600 was used in western blot to examine the relationship between NEDD4 and IFITM3
Sat Aug 01 00:00:00 EDT 2015
E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3.
PLoS pathogens
Chesarino NM,McMichael TM,Yount JS
39-8600 was used in western blot to examine the relationship between NEDD4 and IFITM3
Sat Aug 01 00:00:00 EDT 2015
Salmonella Engages Host MicroRNAs To Modulate SUMOylation: a New Arsenal for Intracellular Survival.
Molecular and cellular biology
Verma S,Mohapatra G,Ahmad SM,Rana S,Jain S,Khalsa JK,Srikanth CV
39-8600 was used in western blot to report that Salmonella enterica serovar Typhimurium modulates host SUMOylation.
Tue Sep 01 00:00:00 EDT 2015
Overexpression of miR-18a negatively regulates myocyte enhancer factor 2D to increase the permeability of the blood-tumor barrier via Krüppel-like factor 4-mediated downregulation of zonula occluden-1, claudin-5, and occludin.
Journal of neuroscience research
Zhao YY,Zhao LN,Wang P,Miao YS,Liu YH,Wang ZH,Ma J,Li Z,Li ZQ,Xue YX
39-8600 was used in western blot to elucidate the effects and mechanism of miR-18a on the permeability of the blood-tumor barrier.
Tue Dec 01 00:00:00 EST 2015
Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport.
Neuroscience
Štalekar M,Yin X,Rebolj K,Darovic S,Troakes C,Mayr M,Shaw CE,Rogelj B
39-8600 was used in western blot to study the effect of loss of Transactive response DNA-binding protein 43 on the proteome
Thu May 07 00:00:00 EDT 2015
BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells.
Oncotarget
Coudé MM,Braun T,Berrou J,Dupont M,Bertrand S,Masse A,Raffoux E,Itzykson R,Delord M,Riveiro ME,Herait P,Baruchel A,Dombret H,Gardin C
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Fri Jul 10 00:00:00 EDT 2015
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nature structural & molecular biology
Ni Z,Xu C,Guo X,Hunter GO,Kuznetsova OV,Tempel W,Marcon E,Zhong G,Guo H,Kuo WW,Li J,Young P,Olsen JB,Wan C,Loppnau P,El Bakkouri M,Senisterra GA,He H,Huang H,Sidhu SS,Emili A,Murphy S,Mosley AL,Arrowsmith CH,Min J,Greenblatt JF
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Fri Aug 01 00:00:00 EDT 2014
Effects of detraining on the temporal expression of positive and negative angioregulatory proteins in skeletal muscle of mice.
The Journal of physiology
Olenich SA,Audet GN,Roberts KA,Olfert IM
39-8600 was used in western blot to measure the protein expression of anti-angiogenic peptides, pro-angiogenic factors, and nucleolin in response to detraining in triceps surae muscles of mice
Fri Aug 01 00:00:00 EDT 2014
Connexin40 abnormalities and atrial fibrillation in the human heart.
Journal of molecular and cellular cardiology
Gemel J,Levy AE,Simon AR,Bennett KB,Ai X,Akhter S,Beyer EC
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Sat Nov 01 00:00:00 EDT 2014
Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination.
The Journal of biological chemistry
Chesarino NM,McMichael TM,Hach JC,Yount JS
39-8600 was used in western blot to investigate how phosphorylation controls IFITM3 trafficking and degradation.
Fri Apr 25 00:00:00 EDT 2014
Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination.
The Journal of biological chemistry
Chesarino NM,McMichael TM,Hach JC,Yount JS
39-8600 was used in western blot to investigate how phosphorylation controls IFITM3 trafficking and degradation.
Fri Apr 25 00:00:00 EDT 2014
Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease.
PloS one
Maarouf CL,Kokjohn TA,Walker DG,Whiteside CM,Kalback WM,Whetzel A,Sue LI,Serrano G,Jacobson SA,Sabbagh MN,Reiman EM,Beach TG,Roher AE
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Oct 05 00:00:00 EDT 2015
Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis.
PloS one
Calabro SR,Maczurek AE,Morgan AJ,Tu T,Wen VW,Yee C,Mridha A,Lee M,d'Avigdor W,Locarnini SA,McCaughan GW,Warner FJ,McLennan SV,Shackel NA
39-8600 was used in western blot to test if hepatocytes produce MMPs, regulated by CD147, that remodel fibrotic extracellular matrix independent of HSC
Thu Nov 12 00:00:00 EST 2015
The small cell lung cancer-specific isoform of RE1-silencing transcription factor (REST) is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100).
Molecular cancer research : MCR
Shimojo M,Shudo Y,Ikeda M,Kobashi T,Ito S
Tue Oct 01 00:00:00 EDT 2013
Temporal response of positive and negative regulators in response to acute and chronic exercise training in mice.
The Journal of physiology
Olenich SA,Gutierrez-Reed N,Audet GN,Olfert IM
Tue Oct 15 00:00:00 EDT 2013
Canine chondrodysplasia caused by a truncating mutation in collagen-binding integrin alpha subunit 10.
PloS one
Kyöstilä K,Lappalainen AK,Lohi H
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Mon Jul 14 00:00:00 EDT 2014
Exosomes are natural carriers of exogenous siRNA to human cells in vitro.
Cell communication and signaling : CCS
Shtam TA,Kovalev RA,Varfolomeeva EY,Makarov EM,Kil YV,Filatov MV
39-8600 was used in western blot to discuss using exosomes to deliver siRNA.
Mon Nov 18 00:00:00 EST 2013
Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.
American journal of neurodegenerative disease
Roher AE,Maarouf CL,Malek-Ahmadi M,Wilson J,Kokjohn TA,Daugs ID,Whiteside CM,Kalback WM,Macias MP,Jacobson SA,Sabbagh MN,Ghetti B,Beach TG
39-8600 was used in Western Blotting to study PSEN mutations by quantifying the white matter (WM) levels of Aβ peptides, as well as 21 other WM proteins and 2 grey matter synaptic molecules.
Fri Oct 04 00:00:00 EDT 2013
Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1.
Molecular cancer research : MCR
Botta GP,Reginato MJ,Reichert M,Rustgi AK,Lelkes PI
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Wed Feb 01 00:00:00 EST 2012
Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma.
Laboratory investigation; a journal of technical methods and pathology
Li L,Sarver AL,Alamgir S,Subramanian S
39-8600 was used in western blot to report that downregulation of miR-, -206. and -29 stabilizes expression of PAX3 and CCND2.
Sun Apr 01 00:00:00 EDT 2012
Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma.
Laboratory investigation; a journal of technical methods and pathology
Li L,Sarver AL,Alamgir S,Subramanian S
39-8600 was used in western blot to report that downregulation of miR-, -206. and -29 stabilizes expression of PAX3 and CCND2.
Sun Apr 01 00:00:00 EDT 2012
Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions.
Molecular membrane biology
Paschoud S,Yu D,Pulimeno P,Jond L,Turner JR,Citi S
Tue Feb 01 00:00:00 EST 2011
Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy.
Circulation
Gianni D,Li A,Tesco G,McKay KM,Moore J,Raygor K,Rota M,Gwathmey JK,Dec GW,Aretz T,Leri A,Semigran MJ,Anversa P,Macgillivray TE,Tanzi RE,del Monte F
39-8600 was used in Western Blotting to characterise fibrillar and oligomeric assemblies in the hearts of idiopathic dilated cardiomyopathy patients.
Tue Mar 16 00:00:00 EDT 2010
Adenoviral E4orf3 and E4orf6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo.
International journal of radiation oncology, biology, physics
Liikanen I,Dias JD,Nokisalmi P,Sloniecka M,Kangasniemi L,Rajecki M,Dobner T,Tenhunen M,Kanerva A,Pesonen S,Ahtiainen L,Hemminki A
Mon Nov 15 00:00:00 EST 2010
Adenoviral E4orf3 and E4orf6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo.
International journal of radiation oncology, biology, physics
Liikanen I,Dias JD,Nokisalmi P,Sloniecka M,Kangasniemi L,Rajecki M,Dobner T,Tenhunen M,Kanerva A,Pesonen S,Ahtiainen L,Hemminki A
Mon Nov 15 00:00:00 EST 2010
Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.
Journal of neuroscience research
Spatara ML,Robinson AS
39-8600 was used in western blot to elucidate the between tau aggregation and the unfolded protein response in neurodegenerative disorders
Thu Jul 01 00:00:00 EDT 2010
Occurrence and regional distribution of TRAIL and DR5 on temporomandibular joint discs: comparison of disc derangement with and without reduction.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Leonardi R,Almeida LE,Trevilatto PC,Loreto C
Mon Feb 01 00:00:00 EST 2010
Occurrence and regional distribution of TRAIL and DR5 on temporomandibular joint discs: comparison of disc derangement with and without reduction.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Leonardi R,Almeida LE,Trevilatto PC,Loreto C
Mon Feb 01 00:00:00 EST 2010
Occurrence and regional distribution of TRAIL and DR5 on temporomandibular joint discs: comparison of disc derangement with and without reduction.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Leonardi R,Almeida LE,Trevilatto PC,Loreto C
Mon Feb 01 00:00:00 EST 2010
Occurrence and regional distribution of TRAIL and DR5 on temporomandibular joint discs: comparison of disc derangement with and without reduction.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Leonardi R,Almeida LE,Trevilatto PC,Loreto C
Mon Feb 01 00:00:00 EST 2010
Role of c-Myb during prolactin-induced signal transducer and activator of transcription 5a signaling in breast cancer cells.
Endocrinology
Fang F,Rycyzyn MA,Clevenger CV
39-8600 was used in western blot to study mechanisms of Stat5a regulation in breast cancer.
Wed Apr 01 00:00:00 EDT 2009
Quantitative proteomics characterization of a mouse embryonic stem cell model of Down syndrome.
Molecular & cellular proteomics : MCP
Wang Y,Mulligan C,Denyer G,Delom F,Dagna-Bricarelli F,Tybulewicz VL,Fisher EM,Griffiths WJ,Nizetic D,Groet J
Published figure using GAPDH monoclonal antibody (Product # 39-8600) in Western Blot
Wed Apr 01 00:00:00 EDT 2009
Function of caspase-14 in trophoblast differentiation.
Reproductive biology and endocrinology : RB&E
White LJ,Declercq W,Arfuso F,Charles AK,Dharmarajan AM
Mon Sep 14 00:00:00 EDT 2009
Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion.
Circulation
Prunier F,Kawase Y,Gianni D,Scapin C,Danik SB,Ellinor PT,Hajjar RJ,Del Monte F
39-8600 was used in western blot to test if sarcoplasmic reticulum Ca2+ ATPase pump overexpression reduces ischemic ventricular arrhythmias by modulating calcium overload
Tue Aug 05 00:00:00 EDT 2008
Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.
Journal of neurochemistry
Nguyen TV,Galvan V,Huang W,Banwait S,Tang H,Zhang J,Bredesen DE
Fri Feb 01 00:00:00 EST 2008
Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.
Journal of neurochemistry
Nguyen TV,Galvan V,Huang W,Banwait S,Tang H,Zhang J,Bredesen DE
Fri Feb 01 00:00:00 EST 2008
Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter.
BMC biotechnology
Fang F,Antico G,Zheng J,Clevenger CV
Wed Feb 06 00:00:00 EST 2008
