Product References
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Molecular medicine reports
Xiao S,Zhou Y,Gao H,Yang D
Sun Jan 01 00:00:00 EST 2023
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Molecular neurobiology
Zhan S,Liang J,Lin H,Cai J,Yang X,Wu H,Wei J,Wang S,Xian M
Sun Jan 01 00:00:00 EST 2023
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Oxidative medicine and cellular longevity
Chen H,Li Z,Xu J,Zhang N,Chen J,Wang G,Zhao Y
Mon Jan 30 00:00:00 EST 2023
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
International journal of molecular sciences
Lai K,Song C,Gao M,Deng Y,Lu Z,Li N,Geng Q
Tue Mar 07 00:00:00 EST 2023
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling.
Cell stress & chaperones
Zhang MW,Li XT,Zhang ZZ,Liu Y,Song JW,Liu XM,Chen YH,Wang N,Guo Y,Liang LR,Zhong JC
Sun Jan 01 00:00:00 EST 2023
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma.
International journal of radiation oncology, biology, physics
Heng J,Li Z,Liu L,Zheng Z,Zheng Y,Xu X,Liao L,Xu H,Huang H,Li E,Xu L
Wed Nov 15 00:00:00 EST 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 EDT 2023
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.
International journal of molecular sciences
Cardile A,Zanrè V,Campagnari R,Asson F,Addo SS,Orlandi E,Menegazzi M
Mon Jan 09 00:00:00 EST 2023
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Apoptosis : an international journal on programmed cell death
Li W,Li W,Li X,Wang L,Wang Y
Tue Aug 01 00:00:00 EDT 2023
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Biochemical and biophysical research communications
Jiang Z,Sun H,Miao J,Sheng Q,Xu J,Gao Z,Zhang X,Song Y,Chen K
Sun Jan 15 00:00:00 EST 2023
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Frontiers in pharmacology
Liu X,Peng X,Cen S,Yang C,Ma Z,Shi X
Tue Mar 14 00:00:00 EDT 2023
TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
Oncogene
Wei J,Wang L,Zhang Y,Sun T,Zhang C,Hu Z,Zhou L,Liu X,Wan J,Ma L
Thu Jun 01 00:00:00 EDT 2023
Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors.
Phytochemistry
Liang X,Wei Y,Hou X,Guo Q,Liang H,Zeng K,Tu P,Zhang Q
Wed Feb 01 00:00:00 EST 2023
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Asian journal of andrology
Li L,Wang MY,Jiang HB,Guo CR,Zhu XD,Yao XQ,Zeng WW,Zhao Y,Chi LK
Fri Apr 28 00:00:00 EDT 2023
Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis.
Asian journal of andrology
Li L,Wang MY,Jiang HB,Guo CR,Zhu XD,Yao XQ,Zeng WW,Zhao Y,Chi LK
Fri Apr 28 00:00:00 EDT 2023
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
ACS applied materials & interfaces
Zhao X,Zhang S,Gao S,Chang HM,Leung PCK,Tan J
Wed Mar 29 00:00:00 EDT 2023
An ultrasensitive GSH-specific fluorescent probe unveils celastrol-induced ccRCC ferroptosis.
Bioorganic chemistry
Li H,Deng C,Zhu N,Zhang C,Zeng Q,Qin L
Mon May 01 00:00:00 EDT 2023
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Animals : an open access journal from MDPI
Li Y,Zhang G,Wen F,Xian M,Guo S,Zhang X,Feng X,Hu Z,Hu J
Sun Apr 23 00:00:00 EDT 2023
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Frontiers in pharmacology
Gao Y,Zhang Z,Du J,Yang X,Wang X,Wen K,Sun X
Tue May 09 00:00:00 EDT 2023
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yang X,Chen Y,Guo J,Li J,Zhang P,Yang H,Rong K,Zhou T,Fu J,Zhao J
Mon May 01 00:00:00 EDT 2023
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yang X,Chen Y,Guo J,Li J,Zhang P,Yang H,Rong K,Zhou T,Fu J,Zhao J
Mon May 01 00:00:00 EDT 2023
Berberine hydrochloride alleviates imatinib mesylate - induced cardiotoxicity through the inhibition of Nrf2-dependent ferroptosis.
Food & function
Song C,Li D,Zhang J,Zhao X
Mon Jan 23 00:00:00 EST 2023
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
International journal of biological sciences
Zhou C,Yu T,Zhu R,Lu J,Ouyang X,Zhang Z,Chen Q,Li J,Cui J,Jiang F,Jin KY,Sarapultsev A,Li F,Zhang G,Luo S,Hu D
Tue Apr 18 00:00:00 EDT 2023
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
International journal of biological sciences
Zhou C,Yu T,Zhu R,Lu J,Ouyang X,Zhang Z,Chen Q,Li J,Cui J,Jiang F,Jin KY,Sarapultsev A,Li F,Zhang G,Luo S,Hu D
Tue Apr 18 00:00:00 EDT 2023
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu G,Yuan Z,Wang J
Mon May 01 00:00:00 EDT 2023
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu G,Yuan Z,Wang J
Mon May 01 00:00:00 EDT 2023
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
The journal of gene medicine
Yao B,Cai Y,Wan L,Deng J,Zhao L,Wang W,Han Z
Thu Jun 01 00:00:00 EDT 2023
Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis.
Cancer cell international
Yan X,Liu Y,Li C,Mao X,Xu T,Hu Z,Zhang C,Lin N,Lin Y,Zhang Y
Tue Jun 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Neurotoxicity research
Lin S,Cheng H,Yang G,Wang C,Leung CK,Zhang S,Tan Y,Zhang H,Wang H,Miao L,Li Y,Huang Y,Li J,Zhang R,Zeng X
Sun Oct 01 00:00:00 EDT 2023
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Neurotoxicity research
Lin S,Cheng H,Yang G,Wang C,Leung CK,Zhang S,Tan Y,Zhang H,Wang H,Miao L,Li Y,Huang Y,Li J,Zhang R,Zeng X
Sun Oct 01 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
Ferroptosis mediates decabromodiphenyl ether-induced liver damage and inflammation.
Ecotoxicology and environmental safety
Wang Y,Zhang Y,Xue J,Gao L,Li X,Zhao M,Zhao D,Zhou X
Sat Apr 15 00:00:00 EDT 2023
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Drug design, development and therapy
Yin X,Yang Q,Li H,Kang Y,Li Z
Fri Feb 10 00:00:00 EST 2023
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Free radical biology & medicine
Fan J,Xu X,Li Y,Zhang L,Miao M,Niu Y,Zhang Y,Zhang A,Jia Z,Wu M
Sun Jan 01 00:00:00 EST 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
International journal of molecular sciences
Wang Q,Ke S,Liu Z,Shao H,He M,Guo J
Tue Mar 07 00:00:00 EST 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ecotoxicology and environmental safety
Ding S,Jiang J,Zhang G,Yu M,Zheng Y
Mon May 01 00:00:00 EDT 2023
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Journal of controlled release : official journal of the Controlled Release Society
Zhang M,Wang L,Jin H,Zhao N,Liu Y,Lan S,Liu S,Zhang H
Thu Jun 01 00:00:00 EDT 2023
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Cell death & disease
Hao J,Chen Q,Feng Y,Jiang Q,Sun H,Deng B,Huang X,Guan J,Chen Q,Liu X,Wang Y,Cao P,Feng F,Li X
Thu Apr 06 00:00:00 EDT 2023
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Life sciences
Sun X,Huang N,Li P,Dong X,Yang J,Zhang X,Zong WX,Gao S,Xin H
Mon May 15 00:00:00 EDT 2023
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Sexual medicine
Tan XH,Gu YY,Song WP,Nan TG,Song WD,Fang D,Yuan YM,Xin ZC,Li XS,Guan RL
Wed Feb 01 00:00:00 EST 2023
Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4.
PeerJ
Jia C,Zhang X,Qu T,Wu X,Li Y,Zhao Y,Sun L,Wang Q
Wed Feb 15 00:00:00 EST 2023
Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4.
PeerJ
Jia C,Zhang X,Qu T,Wu X,Li Y,Zhao Y,Sun L,Wang Q
Wed Feb 15 00:00:00 EST 2023
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Brain research
Qin Y,Bai D,Tang M,Zhang M,Zhao L,Li J,Yang R,Jiang G
Tue Aug 01 00:00:00 EDT 2023
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Brain research
Qin Y,Bai D,Tang M,Zhang M,Zhao L,Li J,Yang R,Jiang G
Tue Aug 01 00:00:00 EDT 2023
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Biochemical pharmacology
Huang P,Zhao H,Pan X,Li J,Pan W,Dai H,Wang J,Xia C,Liu F
Sat Jul 01 00:00:00 EDT 2023
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Frontiers in bioscience (Landmark edition)
Xiong D,Hu W,Han X,Cai Y
Thu May 25 00:00:00 EDT 2023
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Frontiers in bioscience (Landmark edition)
Xiong D,Hu W,Han X,Cai Y
Thu May 25 00:00:00 EDT 2023
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
International immunopharmacology
Xing L,Dong W,Chen Y,Dai W,Xiao X,Liu Z,Zhang X,Bai D,Xu H
Sun Jan 01 00:00:00 EST 2023
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
International immunopharmacology
Xing L,Dong W,Chen Y,Dai W,Xiao X,Liu Z,Zhang X,Bai D,Xu H
Sun Jan 01 00:00:00 EST 2023
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
International immunopharmacology
Xing L,Dong W,Chen Y,Dai W,Xiao X,Liu Z,Zhang X,Bai D,Xu H
Sun Jan 01 00:00:00 EST 2023
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.
International immunopharmacology
Xing L,Dong W,Chen Y,Dai W,Xiao X,Liu Z,Zhang X,Bai D,Xu H
Sun Jan 01 00:00:00 EST 2023
Yiqi Chutan Formula Reverses Cisplatin-Induced Apoptosis and Ferroptosis of Skeletal Muscle by Alleviating Oxidative Stress.
Integrative cancer therapies
Wu Y,Pi D,Zhou S,Wang W,Ye H,Yi Z,Chen Y,Ouyang M
Thu May 04 00:00:00 EDT 2023
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Journal of physiology and biochemistry
Wang K,Li Z,Ding Y,Liu Z,Li Y,Liu X,Sun Y,Hong J,Zheng W,Qian L,Xu D
Mon May 01 00:00:00 EDT 2023
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Free radical biology & medicine
Liang P,Zhang X,Zhang Y,Wu Y,Song Y,Wang X,Chen T,Liu W,Peng B,Yin J,He F,Fan Y,Han S,He X
Wed Feb 01 00:00:00 EST 2023
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Free radical biology & medicine
Liang P,Zhang X,Zhang Y,Wu Y,Song Y,Wang X,Chen T,Liu W,Peng B,Yin J,He F,Fan Y,Han S,He X
Wed Feb 01 00:00:00 EST 2023
Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury.
Annals of translational medicine
Mei T,Wu J,Wu K,Zhao M,Luo J,Liu X,Shang B,Xu W,Yang Z,Lai Y,Liu C,Gong H,Gao X,Zhuo Y,Lin M,Zhao L
Sun Jan 15 00:00:00 EST 2023
MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.
Reproductive sciences (Thousand Oaks, Calif.)
Mao Y,Wang M,Xiong Y,Wen X,Zhang M,Ma L,Zhang Y
Mon May 01 00:00:00 EDT 2023
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Cell host & microbe
Zeng Y,Wu R,Wang F,Li S,Li L,Li Y,Qin P,Wei M,Yang J,Wu J,Chen A,Ke G,Yan Z,Yang H,Chen Z,Wang Z,Xiao W,Jiang Y,Chen X,Zeng Z,Zhao X,Chen P,Gong S
Wed May 10 00:00:00 EDT 2023
Glutathione ameliorates the meiotic defects of copper exposed ovine oocytes via inhibiting the mitochondrial dysfunctions.
Ecotoxicology and environmental safety
Ren J,Wang B,Li L,Li S,Ma Y,Su L,Liu G,Liu Y,Dai Y
Wed Feb 01 00:00:00 EST 2023
Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway.
Journal of ethnopharmacology
Zhang J,Wang X,Guan B,Wang X,An X,Wang T,Chen X,Zhao L,Jia J,Song L,Ma D,Li Q,Zhang H,Ju J,Xu H
Mon Jan 30 00:00:00 EST 2023
Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway.
Journal of ethnopharmacology
Zhang J,Wang X,Guan B,Wang X,An X,Wang T,Chen X,Zhao L,Jia J,Song L,Ma D,Li Q,Zhang H,Ju J,Xu H
Mon Jan 30 00:00:00 EST 2023
Toosendanin induced hepatotoxicity via triggering PERK-eIF2α-ATF4 mediated ferroptosis.
Toxicology letters
Liang Y,Chen S,Han S,Luo L,Shen F,Huang Z
Wed Mar 15 00:00:00 EDT 2023
PM2.5 caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis.
The Science of the total environment
Wang J,Zhang Z,Shi F,Li Y,Tang Y,Liu C,Wang Y,Chen J,Jiang X,Yang H,Sun L,Chen Q,Ao L,Han F,Liu J,Cao J
Wed May 10 00:00:00 EDT 2023
PM2.5 caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis.
The Science of the total environment
Wang J,Zhang Z,Shi F,Li Y,Tang Y,Liu C,Wang Y,Chen J,Jiang X,Yang H,Sun L,Chen Q,Ao L,Han F,Liu J,Cao J
Wed May 10 00:00:00 EDT 2023
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Neural regeneration research
Yu Z,Cheng X,Pan W,Yu C,Duan Y
Wed Nov 01 00:00:00 EDT 2023
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Neural regeneration research
Yu Z,Cheng X,Pan W,Yu C,Duan Y
Wed Nov 01 00:00:00 EDT 2023
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Oxidative medicine and cellular longevity
Chen Y,Zhang H,Li Y,Wang T
Mon Feb 06 00:00:00 EST 2023
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Journal of neurochemistry
Li R,Zhang X,Gu L,Yuan Y,Luo X,Shen W,Xie Z
Mon May 01 00:00:00 EDT 2023
DiDang decoction improves mitochondrial function and lipid metabolism via the HIF-1 signaling pathway to treat atherosclerosis and hyperlipidemia.
Journal of ethnopharmacology
Wu X,Pan J,Yu JJ,Kang J,Hou S,Cheng M,Xu L,Gong L,Li Y
Tue May 23 00:00:00 EDT 2023
Overexpression of GPX4 attenuates cognitive dysfunction through inhibiting hippocampus ferroptosis and neuroinflammation after traumatic brain injury.
Free radical biology & medicine
Fang J,Yuan Q,Du Z,Zhang Q,Yang L,Wang M,Yang W,Yuan C,Yu J,Wu G,Hu J
Tue Aug 01 00:00:00 EDT 2023
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Toxicology and applied pharmacology
Qi Y,Hu M,Qiu Y,Zhang L,Yan Y,Feng Y,Feng C,Hou X,Wang Z,Zhang D,Zhao J
Sat Apr 15 00:00:00 EDT 2023
Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
CNS neuroscience & therapeutics
Li D,Lu X,Xu G,Liu S,Gong Z,Lu F,Xia X,Jiang J,Wang H,Zou F,Ma X
Sat Jul 01 00:00:00 EDT 2023
Identification of Novel Targets for Treatment of Dilated Cardiomyopathy Based on the Ferroptosis and Immune Heterogeneity.
Journal of inflammation research
Lu H,Xie Y,Zhou Z,Hong P,Chen J
Tue Jun 20 00:00:00 EDT 2023
Reversal of H2O2-induced cell death by knockdown of HOTAIR in HTR-8/SVneo cells by mediation of miR-106b-5p/ACSL4 axis.
Functional & integrative genomics
Cao M,Jin W,Li Y,Wang M,Wan F,Ren Y,Gu Y,Ma J,Zhang L
Mon May 15 00:00:00 EDT 2023
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Acta biochimica et biophysica Sinica
Wu Y,Pi D,Zhou S,Yi Z,Dong Y,Wang W,Ye H,Chen Y,Zuo Q,Ouyang M
Wed Apr 19 00:00:00 EDT 2023
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Acta biochimica et biophysica Sinica
Wu Y,Pi D,Zhou S,Yi Z,Dong Y,Wang W,Ye H,Chen Y,Zuo Q,Ouyang M
Wed Apr 19 00:00:00 EDT 2023
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Acta biochimica et biophysica Sinica
Wu Y,Pi D,Zhou S,Yi Z,Dong Y,Wang W,Ye H,Chen Y,Zuo Q,Ouyang M
Wed Apr 19 00:00:00 EDT 2023
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Acta biochimica et biophysica Sinica
Wu Y,Pi D,Zhou S,Yi Z,Dong Y,Wang W,Ye H,Chen Y,Zuo Q,Ouyang M
Wed Apr 19 00:00:00 EDT 2023
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu S,Cao X,Zhang T,Zhang C,Qu J,Sun Y,Lv W,Qu F
Sun Jan 01 00:00:00 EST 2023
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu S,Cao X,Zhang T,Zhang C,Qu J,Sun Y,Lv W,Qu F
Sun Jan 01 00:00:00 EST 2023
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu S,Cao X,Zhang T,Zhang C,Qu J,Sun Y,Lv W,Qu F
Sun Jan 01 00:00:00 EST 2023
Targeting the Na+/K+ ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity.
Free radical biology & medicine
Leng B,Deng L,Tan J,Lee WT,Cao CR,Wang ZP,Huang DJ,Nie X,Bian JS
Tue Aug 01 00:00:00 EDT 2023
Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.
Molecules (Basel, Switzerland)
Cao W,Li Y,Zeng Z,Lei S
Thu Jun 08 00:00:00 EDT 2023
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Life sciences
Liu Q,Xu L,Ren G,Zhao J,Shao Y,Lu T
Mon May 15 00:00:00 EDT 2023
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway.
Life sciences
Liu Q,Xu L,Ren G,Zhao J,Shao Y,Lu T
Mon May 15 00:00:00 EDT 2023
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cell death & disease
Cheng L,He Q,Liu B,Chen L,Lv F,Li X,Li Y,Liu C,Song Y,Xing Y
Tue Jan 31 00:00:00 EST 2023
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cell death & disease
Cheng L,He Q,Liu B,Chen L,Lv F,Li X,Li Y,Liu C,Song Y,Xing Y
Tue Jan 31 00:00:00 EST 2023
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
BioFactors (Oxford, England)
Xu W,Ding J,Li B,Sun T,You X,He Q,Sheng W
Wed Mar 01 00:00:00 EST 2023
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Cell death & disease
Wang G,Qin S,Chen L,Geng H,Zheng Y,Xia C,Yao J,Deng L
Tue Apr 25 00:00:00 EDT 2023
Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.
Chemico-biological interactions
Liu Y,Chen W,Cen Y,Zhao X,Chen Z,Liang Y,Huang Z,He X,Yang G
Mon May 01 00:00:00 EDT 2023
Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway.
International immunopharmacology
Jin H,Zhao K,Li J,Xu Z,Liao S,Sun S
Sat Apr 01 00:00:00 EDT 2023
Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway.
International immunopharmacology
Jin H,Zhao K,Li J,Xu Z,Liao S,Sun S
Sat Apr 01 00:00:00 EDT 2023
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner.
Oxidative medicine and cellular longevity
Zhou Y,Qian W,Li X,Wei W
Fri Jan 27 00:00:00 EST 2023
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Bioengineering & translational medicine
Wang Y,Xie K,Chen W,Fang Y,Mo Q,Zhang H,Zhao X,Li D,Tan W,Zhao P,Li F
Mon May 01 00:00:00 EDT 2023
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Bioengineering & translational medicine
Wang Y,Xie K,Chen W,Fang Y,Mo Q,Zhang H,Zhao X,Li D,Tan W,Zhao P,Li F
Mon May 01 00:00:00 EDT 2023
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Bioengineering & translational medicine
Wang Y,Xie K,Chen W,Fang Y,Mo Q,Zhang H,Zhao X,Li D,Tan W,Zhao P,Li F
Mon May 01 00:00:00 EDT 2023
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Bioengineering & translational medicine
Wang Y,Xie K,Chen W,Fang Y,Mo Q,Zhang H,Zhao X,Li D,Tan W,Zhao P,Li F
Mon May 01 00:00:00 EDT 2023
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Journal of ethnopharmacology
Zhao F,Peng C,Li H,Chen H,Yang Y,Ai Q,Chen N,Liu F
Sat Oct 28 00:00:00 EDT 2023
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Journal of ethnopharmacology
Zhao F,Peng C,Li H,Chen H,Yang Y,Ai Q,Chen N,Liu F
Sat Oct 28 00:00:00 EDT 2023
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Journal of ethnopharmacology
Zhao F,Peng C,Li H,Chen H,Yang Y,Ai Q,Chen N,Liu F
Sat Oct 28 00:00:00 EDT 2023
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway.
Journal of ethnopharmacology
Zhao F,Peng C,Li H,Chen H,Yang Y,Ai Q,Chen N,Liu F
Sat Oct 28 00:00:00 EDT 2023
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Free radical biology & medicine
Li XT,Song JW,Zhang ZZ,Zhang MW,Liang LR,Miao R,Liu Y,Chen YH,Liu XY,Zhong JC
Sun Nov 20 00:00:00 EST 2022
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Free radical biology & medicine
Li XT,Song JW,Zhang ZZ,Zhang MW,Liang LR,Miao R,Liu Y,Chen YH,Liu XY,Zhong JC
Sun Nov 20 00:00:00 EST 2022
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
Cells
Zhang Z,Ji C,Wang YN,Liu S,Wang M,Xu X,Zhang D
Wed Aug 17 00:00:00 EDT 2022
Insamgobonhwan Protects Neuronal Cells from Lipid ROS and Improves Deficient Cognitive Function.
Antioxidants (Basel, Switzerland)
Yang JH,Nguyen CD,Lee G,Na CS
Mon Jan 31 00:00:00 EST 2022
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Biology
Li B,Wang C,Lu P,Ji Y,Wang X,Liu C,Lu X,Xu X,Wang X
Fri Sep 23 00:00:00 EDT 2022
Edaravone Ameliorates Cerebral Ischemia-Reperfusion Injury by Downregulating Ferroptosis via the Nrf2/FPN Pathway in Rats.
Biological & pharmaceutical bulletin
Liu W,Wang L,Liu C,Dai Z,Li T,Tang B
Thu Sep 08 00:00:00 EDT 2022
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Frontiers in oncology
Li X,Yu Q,Zhao R,Guo X,Liu C,Zhang K,Zhang W,Liu J,Yu J,Wang S,Hao Q,Li W,Zhang W,Li M,Zhang Y,Zhang C,Gao Y
Sat Jul 16 00:00:00 EDT 2022
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Frontiers in oncology
Li X,Yu Q,Zhao R,Guo X,Liu C,Zhang K,Zhang W,Liu J,Yu J,Wang S,Hao Q,Li W,Zhang W,Li M,Zhang Y,Zhang C,Gao Y
Sat Jul 16 00:00:00 EDT 2022
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Frontiers in oncology
Li X,Yu Q,Zhao R,Guo X,Liu C,Zhang K,Zhang W,Liu J,Yu J,Wang S,Hao Q,Li W,Zhang W,Li M,Zhang Y,Zhang C,Gao Y
Sat Jul 16 00:00:00 EDT 2022
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Frontiers in oncology
Li X,Yu Q,Zhao R,Guo X,Liu C,Zhang K,Zhang W,Liu J,Yu J,Wang S,Hao Q,Li W,Zhang W,Li M,Zhang Y,Zhang C,Gao Y
Sat Jul 16 00:00:00 EDT 2022
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Oxidative medicine and cellular longevity
Li X,Wu L,Tian X,Zheng W,Yuan M,Tian X,Zuo H,Song H,Shen Z
Tue Jun 21 00:00:00 EDT 2022
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
Oxidative medicine and cellular longevity
Liu H,Xie J,Fan L,Xia Y,Peng X,Zhou J,Ni X
Fri Apr 15 00:00:00 EDT 2022
Cryptotanshinone Protects against PCOS-Induced Damage of Ovarian Tissue via Regulating Oxidative Stress, Mitochondrial Membrane Potential, Inflammation, and Apoptosis via Regulating Ferroptosis.
Oxidative medicine and cellular longevity
Liu H,Xie J,Fan L,Xia Y,Peng X,Zhou J,Ni X
Fri Apr 15 00:00:00 EDT 2022
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Liu H,Zhao L,Wang M,Yang K,Jin Z,Zhao C,Shi G
Sat Apr 09 00:00:00 EDT 2022
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology
Li X,Chu Y,Ma R,Dou M,Li S,Song Y,Lv Y,Zhu L
Thu Dec 15 00:00:00 EST 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy.
Biomaterials science
Xu X,Chen Y,Gui J,Liu P,Huang Y,Shao B,Ping Y,Li B
Tue Feb 01 00:00:00 EST 2022
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Biochimica et biophysica acta. Molecular basis of disease
Li M,Song D,Chen X,Wang X,Xu L,Yang M,Yang J,Kalvakolanu DV,Wei X,Liu X,Li Y,Guo B,Zhang L
Thu Dec 01 00:00:00 EST 2022
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis.
Journal of orthopaedic surgery and research
Yan J,Feng G,Ma L,Chen Z,Jin Q
Tue Jun 28 00:00:00 EDT 2022
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
Acta cirurgica brasileira
Wang Y,Chen M,Gao Y,He K,Yang Z,Li Y,Zhang S,Zhao L
Thu Dec 15 00:00:00 EST 2022
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Disease markers
Zhang J,Liu Z,Dong Y
Wed Jul 13 00:00:00 EDT 2022
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Oxidative medicine and cellular longevity
Gong H,Gao M,Lin Y,Liu J,Hu Z,Liu J
Wed Sep 28 00:00:00 EDT 2022
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Signal transduction and targeted therapy
Li GN,Zhao XJ,Wang Z,Luo MS,Shi SN,Yan DM,Li HY,Liu JH,Yang Y,Tan JH,Zhang ZY,Chen RQ,Lai HL,Huang XY,Zhou JF,Ma D,Fang Y,Gao QL
Mon Sep 12 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Cellular & molecular biology letters
Li J,Deng SH,Li J,Li L,Zhang F,Zou Y,Wu DM,Xu Y
Sat Mar 19 00:00:00 EDT 2022
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Free radical biology & medicine
Zhang Z,Tang J,Song J,Xie M,Liu Y,Dong Z,Liu X,Li X,Zhang M,Chen Y,Shi H,Zhong J
Tue Mar 01 00:00:00 EST 2022
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Free radical biology & medicine
Zhang Z,Tang J,Song J,Xie M,Liu Y,Dong Z,Liu X,Li X,Zhang M,Chen Y,Shi H,Zhong J
Tue Mar 01 00:00:00 EST 2022
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Cancer cell international
Wang S,Chen L,Liu W
Thu Oct 13 00:00:00 EDT 2022
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Cancer cell international
Wang S,Chen L,Liu W
Thu Oct 13 00:00:00 EDT 2022
Ferritinophagy is Involved in Experimental Subarachnoid Hemorrhage-Induced Neuronal Ferroptosis.
Neurochemical research
Liang Y,Deng Y,Zhao J,Liu L,Wang J,Chen P,Zhang Q,Sun C,Wang Y,Xiang Y,He Z
Tue Mar 01 00:00:00 EST 2022
Ferritinophagy is Involved in Experimental Subarachnoid Hemorrhage-Induced Neuronal Ferroptosis.
Neurochemical research
Liang Y,Deng Y,Zhao J,Liu L,Wang J,Chen P,Zhang Q,Sun C,Wang Y,Xiang Y,He Z
Tue Mar 01 00:00:00 EST 2022
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics.
Frontiers in oncology
Wang Y,Song H,Miao Q,Wang Y,Qi J,Xu X,Sun J
Tue Mar 29 00:00:00 EDT 2022
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Evidence-based complementary and alternative medicine : eCAM
Wu Y,Pi D,Chen Y,Zuo Q,Zhou S,Ouyang M
Sat Jul 16 00:00:00 EDT 2022
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Evidence-based complementary and alternative medicine : eCAM
Wu Y,Pi D,Chen Y,Zuo Q,Zhou S,Ouyang M
Sat Jul 16 00:00:00 EDT 2022
Glutathione Peroxidase 4 as a Therapeutic Target for Anti-Colorectal Cancer Drug-Tolerant Persister Cells.
Frontiers in oncology
Zhang X,Ma Y,Ma J,Yang L,Song Q,Wang H,Lv G
Sat Jul 16 00:00:00 EDT 2022
Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity.
Frontiers in pharmacology
Jiang JJ,Zhang GF,Zheng JY,Sun JH,Ding SB
Sat Jul 16 00:00:00 EDT 2022
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Molecules (Basel, Switzerland)
Li Y,Zhang E,Yang H,Chen Y,Tao L,Xu Y,Chen T,Shen X
Sat Sep 24 00:00:00 EDT 2022
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Frontiers in molecular biosciences
Liang Z,Miao Y,Teng X,Xiao L,Guo Q,Xue H,Tian D,Jin S,Wu Y
Tue Aug 09 00:00:00 EDT 2022
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Free radical biology & medicine
Wang W,Jing X,Du T,Ren J,Liu X,Chen F,Shao Y,Sun S,Yang G,Cui X
Thu Sep 01 00:00:00 EDT 2022
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Free radical biology & medicine
Wang W,Jing X,Du T,Ren J,Liu X,Chen F,Shao Y,Sun S,Yang G,Cui X
Thu Sep 01 00:00:00 EDT 2022
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Redox biology
Wu WY,Wang ZX,Li TS,Ding XQ,Liu ZH,Yang J,Fang L,Kong LD
Wed Jun 01 00:00:00 EDT 2022
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Cell & bioscience
Li J,Li M,Ge Y,Chen J,Ma J,Wang C,Sun M,Wang L,Yao S,Yao C
Thu May 26 00:00:00 EDT 2022
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Pharmacological research
Chang MT,Tsai LC,Nakagawa-Goto K,Lee KH,Shyur LF
Fri Apr 01 00:00:00 EDT 2022
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Pharmacological research
Chang MT,Tsai LC,Nakagawa-Goto K,Lee KH,Shyur LF
Fri Apr 01 00:00:00 EDT 2022
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Pharmacological research
Chang MT,Tsai LC,Nakagawa-Goto K,Lee KH,Shyur LF
Fri Apr 01 00:00:00 EDT 2022
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Pharmacological research
Chang MT,Tsai LC,Nakagawa-Goto K,Lee KH,Shyur LF
Fri Apr 01 00:00:00 EDT 2022
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Cell death discovery
Liang Z,Wu Q,Wang H,Tan J,Wang H,Gou Y,Cao Y,Li Z,Zhang Z
Mon Apr 11 00:00:00 EDT 2022
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Cell death discovery
Liang Z,Wu Q,Wang H,Tan J,Wang H,Gou Y,Cao Y,Li Z,Zhang Z
Mon Apr 11 00:00:00 EDT 2022
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Neuroscience letters
Liu MJ,Zhao XC,Gong HS,You YQ,Li JY
Sun Sep 25 00:00:00 EDT 2022
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Neuroscience letters
Liu MJ,Zhao XC,Gong HS,You YQ,Li JY
Sun Sep 25 00:00:00 EDT 2022
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins.
Antioxidants (Basel, Switzerland)
Miller CE,Xu F,Zhao Y,Luo W,Zhong W,Meyer K,Jayswal R,Weiss HL,St Clair WH,St Clair DK,Chaiswing L
Thu Oct 27 00:00:00 EDT 2022
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
International immunopharmacology
Bao C,Liu C,Liu Q,Hua L,Hu J,Li Z,Xu S
Mon Aug 01 00:00:00 EDT 2022
Attenuation by Time-Restricted Feeding of High-Fat and High-Fructose Diet-Induced NASH in Mice Is Related to Per2 and Ferroptosis.
Oxidative medicine and cellular longevity
Shu YY,Gao WK,Chu HK,Yang L,Pan XL,Ye J
Mon Oct 31 00:00:00 EDT 2022
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
European journal of pharmacology
Wang J,Wen J,Ma X,Yang J,Zhang Z,Xie S,Wei S,Jing M,Li H,Lang L,Zhou X,Zhao Y
Tue Nov 15 00:00:00 EST 2022
Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.
Gene
Fang Y,Fang D
Fri Aug 05 00:00:00 EDT 2022
New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Feng W,Xiao Y,Zhao C,Zhang Z,Liu W,Ma J,Ganz T,Zhang J,Liu S
Sat Oct 01 00:00:00 EDT 2022
GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1.
BMC cancer
Wei S,Yu Z,Shi R,An L,Zhang Q,Zhang Q,Zhang T,Zhang J,Wang H
Fri Aug 12 00:00:00 EDT 2022
GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1.
BMC cancer
Wei S,Yu Z,Shi R,An L,Zhang Q,Zhang Q,Zhang T,Zhang J,Wang H
Fri Aug 12 00:00:00 EDT 2022
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury.
American journal of physiology. Gastrointestinal and liver physiology
Ye J,Peng J,Liu K,Zhang T,Huang W
Thu Sep 01 00:00:00 EDT 2022
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
European journal of medicinal chemistry
Guo J,Cheng M,Liu P,Cao D,Luo J,Wan Y,Fang Y,Jin Y,Xie SS,Liu J
Tue Nov 15 00:00:00 EST 2022
Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats.
Antioxidants (Basel, Switzerland)
Huang Y,Wu H,Hu Y,Zhou C,Wu J,Wu Y,Wang H,Lenahan C,Huang L,Nie S,Gao X,Sun J
Mon Jun 27 00:00:00 EDT 2022
Artemether attenuates renal tubular injury by regulating iron metabolism in mice with streptozotocin-induced diabetes.
American journal of translational research
Rong G,Cai Y,Weng W,Chen Y,Yu X,Shao M,Han P,Sun H
Wed Oct 19 00:00:00 EDT 2022
SLC7A11/GPX4 Inactivation-Mediated Ferroptosis Contributes to the Pathogenesis of Triptolide-Induced Cardiotoxicity.
Oxidative medicine and cellular longevity
Liu X,Chen C,Han D,Zhou W,Cui Y,Tang X,Xiao C,Wang Y,Gao Y
Tue Jun 28 00:00:00 EDT 2022
Hedyotis diffusa injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Huang F,Pang J,Xu L,Niu W,Zhang Y,Li S,Li X
Thu Sep 01 00:00:00 EDT 2022
Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle.
Journal of medicinal chemistry
Wang H,Wu D,Gao C,Teng H,Zhao Y,He Z,Chen W,Zong Y,Du R
Thu Jul 28 00:00:00 EDT 2022
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Cell death & disease
Yi L,Hu Y,Wu Z,Li Y,Kong M,Kang Z,Zuoyuan B,Yang Z
Mon Jul 11 00:00:00 EDT 2022
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Biochemical and biophysical research communications
Sun F,Zhou JL,Liu ZL,Jiang ZW,Peng H
Sat Apr 30 00:00:00 EDT 2022
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head.
Biochemical and biophysical research communications
Sun F,Zhou JL,Liu ZL,Jiang ZW,Peng H
Sat Apr 30 00:00:00 EDT 2022
Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance.
Translational lung cancer research
Zhang C,Wang C,Yang Z,Bai Y,Shukuya T,Poh ME,Ekman S,Li J,Xu Y,Deng S
Sun May 01 00:00:00 EDT 2022
Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation.
BMC cardiovascular disorders
Meng Q,Xu Y,Ling X,Liu H,Ding S,Wu H,Yan D,Fang X,Li T,Liu Q
Fri Jul 29 00:00:00 EDT 2022
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Cancer medicine
Huang R,Zhang C,Wang X,Zou X,Xiang Z,Wang Z,Gui B,Lin T,Hu H
Tue Nov 01 00:00:00 EDT 2022
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Cell communication and signaling : CCS
Zhang Y,Zhang C,Li J,Jiang M,Guo S,Yang G,Zhang L,Wang F,Yi S,Wang J,Fu Y,Zhang Y
Fri Jun 17 00:00:00 EDT 2022
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Human & experimental toxicology
Zhang P,Zhang J,Quan H,Chen P,Wang J,Liang Y
Wed Mar 02 00:00:00 EST 2022
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Frontiers in oncology
Kang X,Huo Y,Jia S,He F,Li H,Zhou Q,Chang N,Liu D,Li R,Hu Y,Zhang P,Xu A
Tue Jul 26 00:00:00 EDT 2022
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Frontiers in oncology
Kang X,Huo Y,Jia S,He F,Li H,Zhou Q,Chang N,Liu D,Li R,Hu Y,Zhang P,Xu A
Tue Jul 26 00:00:00 EDT 2022
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Cell stress & chaperones
Li J,Tang X,Tu X,Jin Z,Dong H,Yang Q,Yao T,Pan Z
Thu Sep 01 00:00:00 EDT 2022
Cadmium induces ferroptosis mediated inflammation by activating Gpx4/Ager/p65 axis in pancreatic β-cells.
The Science of the total environment
Hong H,Lin X,Xu Y,Tong T,Zhang J,He H,Yang L,Lu Y,Zhou Z
Fri Nov 25 00:00:00 EST 2022
Cadmium induces ferroptosis mediated inflammation by activating Gpx4/Ager/p65 axis in pancreatic β-cells.
The Science of the total environment
Hong H,Lin X,Xu Y,Tong T,Zhang J,He H,Yang L,Lu Y,Zhou Z
Fri Nov 25 00:00:00 EST 2022
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
European journal of pharmacology
Hu P,Xu Y,Jiang Y,Huang J,Liu Y,Wang D,Tao T,Sun Z,Liu Y
Fri Aug 05 00:00:00 EDT 2022
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Journal of pharmacological sciences
Cui Z,Wang H,Li S,Qin T,Shi H,Ma J,Li L,Yu G,Jiang T,Li C
Sat Jan 01 00:00:00 EST 2022
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Cardiology research and practice
Peng Y,Liao B,Zhou Y,Zeng W,Zeng ZY
Sat Nov 19 00:00:00 EST 2022
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Reproductive biology and endocrinology : RB&E
Wang P,Zhang S,Lin S,Lv Z
Fri Aug 12 00:00:00 EDT 2022
Notch3 regulates ferroptosis via ROS-induced lipid peroxidation in NSCLC cells.
FEBS open bio
Li Z,Xiao J,Liu M,Cui J,Lian B,Sun Y,Li C
Wed Jun 01 00:00:00 EDT 2022
Notch3 regulates ferroptosis via ROS-induced lipid peroxidation in NSCLC cells.
FEBS open bio
Li Z,Xiao J,Liu M,Cui J,Lian B,Sun Y,Li C
Wed Jun 01 00:00:00 EDT 2022
Calorie Restriction Protects against Contrast-Induced Nephropathy via SIRT1/GPX4 Activation.
Oxidative medicine and cellular longevity
Fang D,Wang Y,Zhang Z,Yang D,Gu D,He B,Zhang X,He D,Wang H,Jose PA,Han Y,Zeng C
Mon Feb 07 00:00:00 EST 2022
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
FEBS open bio
Wei N,Lu T,Yang L,Dong Y,Liu X
Sun Aug 01 00:00:00 EDT 2021
Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.
Journal of oncology
Li H,Zhou W,Wei H,Li L,Wang X,Li Y,Li S,Li C
Sat Dec 18 00:00:00 EST 2021
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Frontiers in immunology
Chen L,Niu X,Qiao X,Liu S,Ma H,Shi X,He X,Zhong M
Fri Apr 08 00:00:00 EDT 2022
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Cell death discovery
Li W,Li W,Wang Y,Leng Y,Xia Z
Wed Sep 29 00:00:00 EDT 2021
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Cell death discovery
Li W,Li W,Wang Y,Leng Y,Xia Z
Wed Sep 29 00:00:00 EDT 2021
Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest.
Frontiers in pharmacology
Xu J,Zhang M,Liu F,Shi L,Jiang X,Chen C,Wang J,Diao M,Khan ZU,Zhang M
Tue Dec 28 00:00:00 EST 2021
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Oxidative medicine and cellular longevity
Li L,Li H,Li Y,Feng J,Guan D,Zhang Y,Fu Y,Li S,Li C
Thu Feb 17 00:00:00 EST 2022
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis.
Cell stress & chaperones
Tian H,Xiong Y,Zhang Y,Leng Y,Tao J,Li L,Qiu Z,Xia Z
Mon Mar 01 00:00:00 EST 2021
Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.
Biochemical and biophysical research communications
Hu X,Luo J,Lai H,Li M,Zheng X,Nie T,Li F,Li H
Wed Sep 05 00:00:00 EDT 2018
