Product References
Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke.
Cell death & disease
Zheng H,Guo X,Kang S,Li Z,Tian T,Li J,Wang F,Yu P,Chang S,Chang YZ
Sat Feb 25 00:00:00 EST 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
Sat Apr 01 00:00:00 EDT 2023
Novel function of Roxadustat (FG-4592) as an anti-shock drug in sepsis by regulating mitochondrial oxidative stress and energy metabolism.
Biochimica et biophysica acta. General subjects
Long G,Pei Z,Wu M,Wei K,Du Y,Wang Q,Zhang Y,Huang S,Chen H,Xia W,Jia Z
Sun Jan 01 00:00:00 EST 2023
Effect of PPARγ on oxidative stress in diabetes-related dry eye.
Experimental eye research
Wang J,Chen S,Zhao X,Guo Q,Yang R,Zhang C,Huang Y,Ma L,Zhao S
Thu Jun 01 00:00:00 EDT 2023
Effect of PPARγ on oxidative stress in diabetes-related dry eye.
Experimental eye research
Wang J,Chen S,Zhao X,Guo Q,Yang R,Zhang C,Huang Y,Ma L,Zhao S
Thu Jun 01 00:00:00 EDT 2023
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Oxidative medicine and cellular longevity
Chen H,Li Z,Xu J,Zhang N,Chen J,Wang G,Zhao Y
Mon Jan 30 00:00:00 EST 2023
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Oxidative medicine and cellular longevity
Chen H,Li Z,Xu J,Zhang N,Chen J,Wang G,Zhao Y
Mon Jan 30 00:00:00 EST 2023
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression.
Oxidative medicine and cellular longevity
Chen H,Li Z,Xu J,Zhang N,Chen J,Wang G,Zhao Y
Mon Jan 30 00:00:00 EST 2023
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
International journal of molecular sciences
Lai K,Song C,Gao M,Deng Y,Lu Z,Li N,Geng Q
Tue Mar 07 00:00:00 EST 2023
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
ACS omega
Feng C,Liu Y,Zhang BY,Zhang H,Shan FY,Li TQ,Zhao ZN,Wang XX,Zhang XY
Tue Jun 13 00:00:00 EDT 2023
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xie L,Zhou C,Wu Y,Fu X,Zhang G,Han X,Xie S,Chen G,Xu H,Deng B,Liu B,Zhou Y,Li A
Thu Jun 01 00:00:00 EDT 2023
Buyang Huanwu decoction alleviates oxidative injury of cerebral ischemia-reperfusion through PKCε/Nrf2 signaling pathway.
Journal of ethnopharmacology
Yin M,Liu Z,Wang J,Gao W
Wed Mar 01 00:00:00 EST 2023
Silver nitroprusside as an efficient chemodynamic therapeutic agent and a peroxynitrite nanogenerator for targeted cancer therapies.
Journal of advanced research
Asif K,Adeel M,Rahman MM,Sfriso AA,Bartoletti M,Canzonieri V,Rizzolio F,Caligiuri I
Wed Mar 22 00:00:00 EDT 2023
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Ecotoxicology and environmental safety
Guo C,Lyu Y,Xia S,Ren X,Li Z,Tian F,Zheng J
Sun Jan 01 00:00:00 EST 2023
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.
Antioxidants (Basel, Switzerland)
Qiao P,Sun Y,Wang Y,Lin S,An Y,Wang L,Liu J,Huang Y,Yang B,Zhou H
Fri Apr 28 00:00:00 EDT 2023
Blue LED light induces cytotoxicity via ROS production and mitochondrial damage in bovine subcutaneous preadipocytes.
Environmental pollution (Barking, Essex : 1987)
Hao W,Zhao C,Li G,Wang H,Li T,Yan P,Wei S
Sat Apr 01 00:00:00 EDT 2023
Neuroprotective effect of a Keap1-Nrf2 Protein-Protein Inter-action inhibitor on cerebral Ischemia/Reperfusion injury.
Bioorganic chemistry
Qi Z,Tong Y,Luo H,Chen M,Zhou N,Chen L
Wed Mar 01 00:00:00 EST 2023
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Journal of ethnopharmacology
Jiang H,Bai Z,Ou Y,Liu H,Si Z,Liu Y,Liu X,Liu X,Zhang Z,Tan N
Wed May 10 00:00:00 EDT 2023
Elevation of HO-1 expression protects the intestinal mucosal barrier in severe acute pancreatitis via inhibition of the MLCK/p-MLC signaling pathway.
Experimental cell research
Zhang J,Jiang Y,Li H,Wang J,Li C,Zhang D
Wed Mar 15 00:00:00 EDT 2023
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Molecular medicine (Cambridge, Mass.)
Chen Y,Liu X,Li L,He X,Zheng F,Zhang Y,Gao H,Jin Z,Wu D,Wang Q,Tao H,Zhao Y,Liu W,Zou L
Mon Feb 06 00:00:00 EST 2023
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Journal of animal science and biotechnology
Shao D,Shen W,Miao Y,Gao Z,Pan M,Wei Q,Yan Z,Zhao X,Ma B
Wed May 03 00:00:00 EDT 2023
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ecotoxicology and environmental safety
Liu X,Xi H,Han S,Zhang H,Hu J
Wed Mar 01 00:00:00 EST 2023
Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP+-Induced SH-SY5Y Cells.
Neurotoxicity research
Lai X,Zhang Y,Wu J,Shen M,Yin S,Yan J
Thu Jun 01 00:00:00 EDT 2023
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Frontiers in pharmacology
Liu X,Peng X,Cen S,Yang C,Ma Z,Shi X
Tue Mar 14 00:00:00 EDT 2023
Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).
Journal of orthopaedic translation
Wang X,Tan Y,Liu F,Wang J,Liu F,Zhang Q,Li J
Wed Mar 01 00:00:00 EST 2023
iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation.
Journal of advanced research
Guo Y,Wen J,He A,Qu C,Peng Y,Luo S,Wang X
Sun Jan 01 00:00:00 EST 2023
Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice.
Frontiers in immunology
Su CJ,Zhang JT,Zhao FL,Xu DL,Pan J,Liu T
Fri Mar 31 00:00:00 EDT 2023
Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.
CNS neuroscience & therapeutics
Xuan LN,Hu ZX,Jiang ZF,Zhang C,Sun XW,Ming WH,Liu HT,Qiao RF,Shen LJ,Liu SB,Wang GY,Wen L,Luan ZL,Yin J
Wed Nov 01 00:00:00 EDT 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Berberine promotes the viability of random skin flaps via the PI3K/Akt/eNOS signaling pathway.
Phytotherapy research : PTR
Chen J,Jiang Z,Liu X,Wang K,Fan W,Chen T,Li Z,Lin D
Wed Feb 01 00:00:00 EST 2023
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe2+ Production.
Current eye research
Liao S,Huang M,Liao Y,Yuan C
Sun Jan 01 00:00:00 EST 2023
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
International urology and nephrology
Wang ZS,Shu B,Han Q,Li GH,Guo YL
Sun Oct 01 00:00:00 EDT 2023
Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice.
International urology and nephrology
Wang ZS,Shu B,Han Q,Li GH,Guo YL
Sun Oct 01 00:00:00 EDT 2023
Liquiritin alleviates alpha-naphthylisothiocyanate-induced intrahepatic cholestasis through the Sirt1/FXR/Nrf2 pathway.
Journal of applied toxicology : JAT
Yan M,Guo L,Ma J,Yang Y,Tang T,Zhang B,Zhou W,Zou W,Hou Z,Gu H,Gong H
Wed Mar 01 00:00:00 EST 2023
PM2.5 exposure increases dry eye disease risks through corneal epithelial inflammation and mitochondrial dysfunctions.
Cell biology and toxicology
Yu D,Cai W,Shen T,Wu Y,Ren C,Li T,Hu C,Zhu M,Yu J
Fri Dec 01 00:00:00 EST 2023
Otoprotective Effects of Fucoidan Reduce Cisplatin-Induced Ototoxicity in Mouse Cochlear UB/OC-2 Cells.
International journal of molecular sciences
Hsieh CY,Lin JN,Kang TY,Wen YH,Yu SH,Wu CC,Wu HP
Fri Feb 10 00:00:00 EST 2023
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Investigative ophthalmology & visual science
Shu N,Zhang Z,Wang X,Li R,Li W,Liu X,Zhang Q,Jiang Z,Tao L,Zhang L,Hou S
Mon May 01 00:00:00 EDT 2023
Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly.
Immunity, inflammation and disease
Gong MJ,Zhang HB,Lou M,Wang YS,Ma RP,Hu ZZ,Zheng GX,Zhang Y
Wed Feb 01 00:00:00 EST 2023
Stimulation of Nuclear Factor (Erythroid-Derived 2)-like 2 Signaling by Nucleus Targeted Irradiation with Proton Microbeam.
Biology
Wang J,Oikawa M,Konishi T
Thu Mar 09 00:00:00 EST 2023
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
The journal of gene medicine
Yao B,Cai Y,Wan L,Deng J,Zhao L,Wang W,Han Z
Thu Jun 01 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 EDT 2023
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Glycobiology
Ise H,Araki Y,Song I,Akatsuka G
Sun Jan 08 00:00:00 EST 2023
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Glycobiology
Ise H,Araki Y,Song I,Akatsuka G
Sun Jan 08 00:00:00 EST 2023
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Glycobiology
Ise H,Araki Y,Song I,Akatsuka G
Sun Jan 08 00:00:00 EST 2023
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Glycobiology
Ise H,Araki Y,Song I,Akatsuka G
Sun Jan 08 00:00:00 EST 2023
Chemical constituents from the stems and leaves of Amomum villosum Lour. and their anti-inflammatory and antioxidant activities.
Bioorganic chemistry
Gao C,Zhu M,Xu W,Wang Y,Xiong L,Sun D,Sun M,Lin Y,Li H,Chen L
Wed Feb 01 00:00:00 EST 2023
Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling.
Iranian journal of basic medical sciences
Li J,Wang G,Zhang Y,Fan X,Yao M
Wed Mar 01 00:00:00 EST 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways.
Journal of ethnopharmacology
Li J,Lu Q,Peng M,Liao J,Zhang B,Yang D,Huang P,Yang Y,Zhao Q,Han B,Li J
Thu Apr 06 00:00:00 EDT 2023
Farnesol Exerts Protective Effects against Chronic Sleep Deprivation-Induced Cognitive Impairment via Activation SIRT1/Nrf2 Pathway in the Hippocampi of Adult Mice.
Molecular nutrition & food research
Li Y,Xie Z,Luo X,Wang X,Wang Y,Guo M,Zhou Z,Sun R,Hua D,Luo A,Li S
Thu Jun 01 00:00:00 EDT 2023
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11.
Neurotoxicity research
Lin S,Cheng H,Yang G,Wang C,Leung CK,Zhang S,Tan Y,Zhang H,Wang H,Miao L,Li Y,Huang Y,Li J,Zhang R,Zeng X
Sun Oct 01 00:00:00 EDT 2023
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
ACS pharmacology & translational science
Wang F,Zhan Y,Li M,Wang L,Zheng A,Liu C,Wang H,Wang T
Fri Jan 13 00:00:00 EST 2023
Andrographolide induced ferroptosis in multiple myeloma cells by regulating the P38/Nrf2/HO-1 pathway.
Archives of biochemistry and biophysics
Li W,Fu H,Fang L,Chai H,Ding B,Qian S
Sat Jul 01 00:00:00 EDT 2023
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
European journal of pharmacology
Li C,Zhang X,Li J,Liang L,Zeng J,Wen M,Pan L,Lv D,Liu M,Cheng Y,Huang H
Mon May 15 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.
Cell metabolism
Kenny TC,Khan A,Son Y,Yue L,Heissel S,Sharma A,Pasolli HA,Liu Y,Gamazon ER,Alwaseem H,Hite RK,Birsoy K
Tue Jun 06 00:00:00 EDT 2023
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
Toxins
Tian Y,Che H,Yang J,Jin Y,Yu H,Wang C,Fu Y,Li N,Zhang J
Tue Mar 21 00:00:00 EDT 2023
Bisphenol S induces oxidative stress-mediated impairment of testosterone synthesis by inhibiting the Nrf2/HO-1 signaling pathway.
Journal of biochemical and molecular toxicology
Wang YX,Dai W,Li YZ,Wu ZY,Kan YQ,Zeng HC,He QZ
Wed Mar 01 00:00:00 EST 2023
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
International immunopharmacology
Guo J,Ren R,Guo Z,Sun K,He J,Shao J,Wang X
Wed Mar 01 00:00:00 EST 2023
LncRNA UCA1 promoted cisplatin resistance in lung adenocarcinoma with HO1 targets NRF2/HO1 pathway.
Journal of cancer research and clinical oncology
Shi W,Ling L,Li C,Wu R,Zhang M,Shao F,Wang Y
Wed Mar 01 00:00:00 EST 2023
Ro25-6981 alleviates neuronal damage and improves cognitive deficits by attenuating oxidative stress via the Nrf2/ARE pathway in ischemia/reperfusion rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Gao X,Chen F,Xu X,Liu J,Dong F,Liu Y
Wed Mar 01 00:00:00 EST 2023
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ma D,Wang Z,He Z,Wang Z,Chen Q,Qin F,Zeng M,Chen J
Sun Jan 01 00:00:00 EST 2023
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Aging cell
Li J,Zhang J,Xue Q,Liu B,Qin R,Li Y,Qiu Y,Wang R,Goltzman D,Miao D,Yang R
Fri Sep 01 00:00:00 EDT 2023
Antibiotics administration alleviates the high fat diet-induced obesity through altering the lipid metabolism in young mice.
Lipids
Luo S,Zhang H,Jiang X,Xia Y,Tang S,Duan X,Sun W,Gao M,Chen C,Zou Z,Zhou L,Qiu J
Sun Jan 01 00:00:00 EST 2023
PM2.5 induce myocardial injury in hyperlipidemic mice through ROS-pyroptosis signaling pathway.
Ecotoxicology and environmental safety
Jia R,Wei M,Lei J,Meng X,Du R,Yang M,Lu X,Jiang Y,Cao R,Wang L,Song L
Sat Apr 01 00:00:00 EDT 2023
Cadmium exposure promotes thyroid pyroptosis and endocrine dysfunction by inhibiting Nrf2/Keap1 signaling.
Ecotoxicology and environmental safety
Chen Y,Zhou C,Bian Y,Fu F,Zhu B,Zhao X,Zhang M,Zhou C,Yao S,Zhang Z,Luo H,Ge Y,Wu C,Ruan H
Sun Jan 01 00:00:00 EST 2023
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
International journal of molecular sciences
Yang CS,Guo XS,Yue YY,Wang Y,Jin XL
Tue Feb 14 00:00:00 EST 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
Neural regeneration research
Wang J,He P,Tian Q,Luo Y,He Y,Liu C,Gong P,Guo Y,Ye Q,Li M
Fri Sep 01 00:00:00 EDT 2023
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Pharmaceutical biology
Ding J,Lu B,Liu L,Zhong Z,Wang N,Li B,Sheng W,He Q
Fri Dec 01 00:00:00 EST 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 EST 2023
Protein kinase D1 promotes the survival of random-pattern skin flaps in rats.
Biochemical and biophysical research communications
Chen J,Chen H,Muhammad I,Han T,Zhang D,Li B,Zhou X,Zhou F
Sun Jan 22 00:00:00 EST 2023
Exosomes derived from bone marrow mesenchymal stem cells alleviate biliary ischemia reperfusion injury in fatty liver transplantation by inhibiting ferroptosis.
Molecular and cellular biochemistry
Tian X,Wu L,Li X,Zheng W,Zuo H,Song H
Sat May 27 00:00:00 EDT 2023
Glycyrrhizin protects against particulate matter-induced lung injury via regulation of endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis through Nrf2/HO-1/NQO1 signaling pathway.
International immunopharmacology
Shi Q,Qian Y,Wang B,Liu L,Chen Y,Chen C,Feng L,Chen J,Dong N
Sat Jul 01 00:00:00 EDT 2023
Ammonia-induced oxidative stress triggered proinflammatory response and apoptosis in pig lungs.
Journal of environmental sciences (China)
Li D,Shen L,Zhang D,Wang X,Wang Q,Qin W,Gao Y,Li X
Sat Apr 01 00:00:00 EDT 2023
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Cell cycle (Georgetown, Tex.)
Zhu J,Sun R,Yan C,Sun K,Gao L,Zheng B,Shi J
Mon May 01 00:00:00 EDT 2023
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Environmental pollution (Barking, Essex : 1987)
Cui M,He Q,Wang Z,Yu Y,Gao H,Liu Z,Peng H,Wang H,Zhang X,Li D,Chen L,Xing X,Xiao Y,Chen W,Wang Q
Tue Aug 01 00:00:00 EDT 2023
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
The Journal of nutrition
Wang G,Qin S,Geng H,Zheng Y,Li R,Xia C,Chen L,Yao J,Deng L
Sat Jul 01 00:00:00 EDT 2023
N6-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.
Ecotoxicology and environmental safety
Ji D,Hu C,Ning J,Ying X,Zhang H,Zhang B,Liu B,Liu Q,Ji W,Zhang R
Sat Apr 01 00:00:00 EDT 2023
N6-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.
Ecotoxicology and environmental safety
Ji D,Hu C,Ning J,Ying X,Zhang H,Zhang B,Liu B,Liu Q,Ji W,Zhang R
Sat Apr 01 00:00:00 EDT 2023
N6-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.
Ecotoxicology and environmental safety
Ji D,Hu C,Ning J,Ying X,Zhang H,Zhang B,Liu B,Liu Q,Ji W,Zhang R
Sat Apr 01 00:00:00 EDT 2023
N6-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.
Ecotoxicology and environmental safety
Ji D,Hu C,Ning J,Ying X,Zhang H,Zhang B,Liu B,Liu Q,Ji W,Zhang R
Sat Apr 01 00:00:00 EDT 2023
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Journal of ethnopharmacology
Zhang X,Wang S,Jin Y,Wang J,Wang R,Yang X,Zhang S,Yan T,Jia Y
Tue May 23 00:00:00 EDT 2023
Non-Lethal Concentrations of CdCl2 Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Toxics
Man Y,Liu Y,Xiong C,Zhang Y,Zhang L
Thu Feb 09 00:00:00 EST 2023
Paricalcitol Ameliorates Acute Kidney Injury in Mice by Suppressing Oxidative Stress and Inflammation via Nrf2/HO-1 Signaling.
International journal of molecular sciences
Wang S,Huang S,Liu X,He Y,Liu Y
Wed Jan 04 00:00:00 EST 2023
Paricalcitol Ameliorates Acute Kidney Injury in Mice by Suppressing Oxidative Stress and Inflammation via Nrf2/HO-1 Signaling.
International journal of molecular sciences
Wang S,Huang S,Liu X,He Y,Liu Y
Wed Jan 04 00:00:00 EST 2023
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Toxicology and applied pharmacology
Xu Z,Zhang M,Wang W,Zhou S,Yu M,Qiu X,Jiang S,Wang X,Tang C,Li S,Wang CH,Zhu R,Peng WX,Zhao L,Fu X,Patzak A,Persson PB,Zhao L,Mao J,Shu Q,Lai EY,Zhang G
Tue Aug 15 00:00:00 EDT 2023
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
International immunopharmacology
Jiang H,Fang Y,Wang Y,Li T,Lin H,Lin J,Pan T,Liu Q,Lv J,Chen D,Chen Y
Wed Mar 01 00:00:00 EST 2023
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Free radical biology & medicine
Zhang Z,Cheng J,Yang L,Li X,Hua R,Xu D,Jiang Z,Li Q
Mon May 01 00:00:00 EDT 2023
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Environmental toxicology
Xi Y,Chi Z,Tao X,Zhai X,Zhao Z,Ren J,Yang S,Dong D
Mon May 01 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Remote preconditioning combined with nebulized budesonide alleviate lipopolysaccharide induced acute lung injury via regulating HO-1 and NF-κB in rats.
Pulmonary pharmacology & therapeutics
Zhao L,Chen Z,Cheng J,Chen B,Liu Y
Thu Jun 01 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
Mst1 attenuates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice through regulating Keap1/Nrf2 axis.
Biochemical and biophysical research communications
Fei Q,Liu J,Qiao L,Zhang M,Xia H,Lu D,Wu D,Wang J,Li R,Li J,Yang F,Liu D,Xie B,Hui W,Qian B
Sun Feb 12 00:00:00 EST 2023
Six first-line tyrosine kinase inhibitors reveal novel inhibition potential for the EGFR S768I mutation.
Toxicology and applied pharmacology
Wang Y,Liu Q,Chu C,Li L,Wang Z,Liu Q,Wu G,Wei X,An L,Ma J
Wed Feb 15 00:00:00 EST 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Journal of dairy science
Chen H,Qi X,Guan K,Wang R,Li Q,Ma Y
Sat Apr 01 00:00:00 EDT 2023
Isoliquiritigenin inhibits virus replication and virus-mediated inflammation via NRF2 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang H,Jia X,Zhang M,Cheng C,Liang X,Wang X,Xie F,Wang J,Yu Y,He Y,Dong Q,Wang Y,Xu A
Thu Jun 01 00:00:00 EDT 2023
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Journal of ethnopharmacology
Wang SJ,Ye W,Li WY,Tian W,Zhang M,Sun Y,Feng YD,Liu CX,Liu SY,Cao W,Meng JR,Li XQ
Wed Mar 01 00:00:00 EST 2023
Hydroquinone triggers pyroptosis and endoplasmic reticulum stress via AhR-regulated oxidative stress in human lymphocytes.
Toxicology letters
Yang X,Dong S,Li C,Li M,Xing C,He J,Peng C,Shao H,Jia Q
Wed Mar 01 00:00:00 EST 2023
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Immunopharmacology and immunotoxicology
Wang X,Yang J,Wang W,Li Y,Yang Y
Sun Oct 01 00:00:00 EDT 2023
Tingli Dazao Decoction pretreatment ameliorates mitochondrial damage induced by oxidative stress in cardiomyocytes.
Journal of ethnopharmacology
Chen H,Zhu Y,Zhao X,Yang Z
Wed Mar 01 00:00:00 EST 2023
Inhibition of YAP by lenvatinib in endothelial cells increases blood pressure through ferroptosis.
Biochimica et biophysica acta. Molecular basis of disease
Liang C,Zhu D,Xia W,Hong Z,Wang QS,Sun Y,Yang YC,Han SQ,Tang LL,Lou J,Wu MM,Zhang ZR
Sun Jan 01 00:00:00 EST 2023
Active Nrf2 signaling flexibly regulates HO-1 and NQO-1 in hypoxic Gansu Zokor (Eospalax cansus).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li M,Peng Y,Chen W,Gao Y,Yang M,Li J,He J
Mon Jan 09 00:00:00 EST 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 EDT 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 EDT 2023
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Acta biochimica et biophysica Sinica
Wu Y,Pi D,Zhou S,Yi Z,Dong Y,Wang W,Ye H,Chen Y,Zuo Q,Ouyang M
Wed Apr 19 00:00:00 EDT 2023
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Toxicology in vitro : an international journal published in association with BIBRA
Kato R,Yamada T,Noda T,Tanaka S,Kohda Y,Ijiri Y
Tue Aug 01 00:00:00 EDT 2023
Reduced SUMOylation of Nrf2 signaling contributes to its inhibition induced by amyloid-β.
Neuroscience letters
Wang P,Wang X,Qiao K,Zhang Y,Nie Q,Cui J,Sun J,Li L
Thu Mar 16 00:00:00 EDT 2023
Antioxidant Peptides from Monkfish Swim Bladders: Ameliorating NAFLD In Vitro by Suppressing Lipid Accumulation and Oxidative Stress via Regulating AMPK/Nrf2 Pathway.
Marine drugs
Wu MF,Xi QH,Sheng Y,Wang YM,Wang WY,Chi CF,Wang B
Fri Jun 16 00:00:00 EDT 2023
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells.
International journal of molecular sciences
Shao D,Gao Z,Zhao Y,Fan M,Zhao X,Wei Q,Pan M,Ma B
Thu Jan 05 00:00:00 EST 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
The American journal of Chinese medicine
Feng Q,Yang Y,Qiao Y,Zheng Y,Yu X,Liu F,Wang H,Zheng B,Pan S,Ren K,Liu D,Liu Z
Mon Jun 19 00:00:00 EDT 2023
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
International immunopharmacology
Yan B,Mao X,Hu S,Wang S,Liu X,Sun J
Thu Jun 01 00:00:00 EDT 2023
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
International immunopharmacology
Yan B,Mao X,Hu S,Wang S,Liu X,Sun J
Thu Jun 01 00:00:00 EDT 2023
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
International immunopharmacology
Li X,Yu X,He S,Li J
Sat Jul 01 00:00:00 EDT 2023
Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles.
Toxicology
Zhang L,Zhang Y,Jiang X,Mao L,Xia Y,Fan Y,Li N,Jiang Z,Qin X,Jiang Y,Liu G,Qiu F,Zhang J,Zou Z,Chen C
Wed Feb 01 00:00:00 EST 2023
BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion.
International immunopharmacology
Guo K,Shang Y,Wang Z,Li Y,Chen J,Zhu B,Zhang D,Chen J
Thu Jun 01 00:00:00 EDT 2023
Protective effects of Lycium barbarum L. berry extracts against oxidative stress-induced damage of the retina of aging mouse and ARPE-19 cells.
Food & function
Zheng HL,Li MT,Zhou T,Wang YY,Shang EX,Hua YQ,Duan JA,Zhu Y
Tue Jan 03 00:00:00 EST 2023
Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.
Frontiers in pharmacology
Chen T,Hu Y,Lu L,Zhao Q,Tao X,Ding B,Chen S,Zhu J,Guo X,Lin Z
Tue Mar 28 00:00:00 EDT 2023
Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.
Frontiers in pharmacology
Chen T,Hu Y,Lu L,Zhao Q,Tao X,Ding B,Chen S,Zhu J,Guo X,Lin Z
Tue Mar 28 00:00:00 EDT 2023
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Phytochemistry
Li M,Zhang Y,Han T,Guan L,Fan D,Wu Q,Liu J,Xu Y,Fan Y
Sun Jan 01 00:00:00 EST 2023
ARE-PROTACs Enable Co-degradation of an Nrf2-MafG Heterodimer.
Journal of medicinal chemistry
Ji J,Ma S,Zhu Y,Zhao J,Tong Y,You Q,Jiang Z
Thu May 11 00:00:00 EDT 2023
Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole.
Pesticide biochemistry and physiology
Feng H,Chen H,Qiang J,Xu B,Wu X,Pan E,Yang H,Li X,Zhang J,Dong J
Sat Apr 01 00:00:00 EDT 2023
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress.
Cardiovascular drugs and therapy
Zhang L,Hu C,Jin B,Bai B,Liao J,Jin L,Wang M,Zhu W,Wu X,Zheng L,Xu X,Jiang Y,Wang Y,He Y
Fri Jan 20 00:00:00 EST 2023
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Cell metabolism
Weiss-Sadan T,Ge M,Hayashi M,Gohar M,Yao CH,de Groot A,Harry S,Carlin A,Fischer H,Shi L,Wei TY,Adelmann CH,Wolf K,Vornbäumen T,Dürr BR,Takahashi M,Richter M,Zhang J,Yang TY,Vijay V,Fisher DE,Hata AN,Haigis MC,Mostoslavsky R,Bardeesy N,Papagiannakopoulos T,Bar-Peled L
Tue Mar 07 00:00:00 EST 2023
Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.
Journal of ethnopharmacology
Zheng R,Shen H,Li J,Zhao J,Lu L,Hu M,Lin Z,Ma H,Tan H,Hu M,Li J
Mon Jan 30 00:00:00 EST 2023
Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.
Nutrients
Chen K,Wang J,Guo L,Wang J,Yang L,Hu T,Zhao Y,Wang X,Zhu Y
Thu Feb 23 00:00:00 EST 2023
Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models.
Foods (Basel, Switzerland)
Han SC,Huang RP,Zhang QY,Yan CY,Li XY,Li YF,He RR,Li WX
Fri Mar 03 00:00:00 EST 2023
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
PLoS genetics
Qin S,Wang G,Chen L,Geng H,Zheng Y,Xia C,Wu S,Yao J,Deng L
Wed Feb 01 00:00:00 EST 2023
SESN2-Mediated AKT/GSK-3β/NRF2 Activation to Ameliorate Adriamycin Cardiotoxicity in High-Fat Diet-Induced Obese Mice.
Antioxidants & redox signaling
Gao T,Wang B J,Xiao M,Wang A J,Wang S,Tang Y,Zhang J,Lu G,Guo H,Guo Y,Liu Q,Li J,Gu J
Thu Aug 03 00:00:00 EDT 2023
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
Food & function
Fan P,Meng H,Hao W,Zheng Y,Li H,Zhang Z,Du L,Guo X,Wang D,Wang Y,Wu H
Mon May 22 00:00:00 EDT 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 EDT 2023
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
The American journal of Chinese medicine
Li Q,Li Z,Liu C,Xu M,Li T,Wang Y,Feng J,Yin X,Du X,Lu C
Mon Jun 19 00:00:00 EDT 2023
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
International immunopharmacology
Huang B,Hu G,Zong X,Yang S,He D,Gao X,Liu D
Wed Feb 01 00:00:00 EST 2023
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu Y,Mi Y,Wang Y,Meng Q,Xu L,Liu Y,Zhou D,Wang Y,Liang D,Li W,Li N,Hou Y
Mon May 01 00:00:00 EDT 2023
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hu Y,Yan Z,He Y,Li Y,Li M,Li Y,Zhang D,Zhao Y,Ommati MM,Wang J,Huo M,Wang J
Sat Apr 01 00:00:00 EDT 2023
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Nature communications
Jiang X,Li M,Wang Y,Wang C,Wang Y,Shen T,Shen L,Liu X,Wang Y,Li X
Tue Mar 14 00:00:00 EDT 2023
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Nature communications
Jiang X,Li M,Wang Y,Wang C,Wang Y,Shen T,Shen L,Liu X,Wang Y,Li X
Tue Mar 14 00:00:00 EDT 2023
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Neurochemical research
Shen M,Zheng Y,Li G,Chen Y,Huang L,Wu J,Hong C
Wed Feb 01 00:00:00 EST 2023
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Journal of hazardous materials
Wu J,Deng F,Tang X,Chen W,Zhou R,Zhao T,Mao X,Shu F
Thu Jun 15 00:00:00 EDT 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 EDT 2022
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Free radical biology & medicine
Lu J,Zhang Y,Dong H,Sun J,Zhu L,Liu P,Wen F,Lin R
Mon Aug 01 00:00:00 EDT 2022
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Antioxidants (Basel, Switzerland)
Xiong L,Wu H,Zhong T,Luo F,Li Q,Li M,Fan Y
Wed Oct 12 00:00:00 EDT 2022
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Journal of agricultural and food chemistry
Wang Q,Wang C,Tian W,Qiu Z,Song M,Cao Y,Xiao J
Wed Feb 23 00:00:00 EST 2022
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 EDT 2022
Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling.
Antioxidants (Basel, Switzerland)
Wang S,Zheng Y,Jin S,Fu Y,Liu Y
Sun Dec 11 00:00:00 EST 2022
Oxidative injury induced by drinking water disinfection by-products dibromoacetonitrile and dichloroacetonitrile in mouse hippocampal neuronal cells: The protective effect of N-acetyl-L-cysteine.
Toxicology letters
Li F,Zhou J,Zhu X,Lu R,Ye Y,Wang S,Xing G,Shen H
Fri Jul 15 00:00:00 EDT 2022
Zoledronic acid induces ferroptosis by reducing ubiquinone and promoting HMOX1 expression in osteosarcoma cells.
Frontiers in pharmacology
Ren T,Huang J,Sun W,Wang G,Wu Y,Jiang Z,Lv Y,Wu G,Cao J,Liu M,Gu H
Wed Feb 01 00:00:00 EST 2023
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Materials today. Bio
Zhang D,Ren Y,He Y,Chang R,Guo S,Ma S,Guan F,Yao M
Wed Jun 01 00:00:00 EDT 2022
Protective effects of hydroxy-α-sanshool from the pericarp of Zanthoxylum bungeanum Maxim. On D-galactose/AlCl3-induced Alzheimer's disease-like mice via Nrf2/HO-1 signaling pathways.
European journal of pharmacology
Liu Y,Meng X,Sun L,Pei K,Chen L,Zhang S,Hu M
Wed Jan 05 00:00:00 EST 2022
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
International immunopharmacology
Wang X,Duan C,Li Y,Lu H,Guo K,Ge X,Chen T,Shang Y,Liu H,Zhang D
Sat Oct 01 00:00:00 EDT 2022
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Molecules (Basel, Switzerland)
Luo JF,Zhou H,Lio CK
Thu Sep 22 00:00:00 EDT 2022
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Molecular medicine reports
Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S
Thu Dec 01 00:00:00 EST 2022
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Frontiers in pharmacology
Fan H,Hao X,Gao Y,Yang J,Liu A,Su Y,Xia Y
Tue Aug 09 00:00:00 EDT 2022
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Frontiers in pharmacology
Fan H,Hao X,Gao Y,Yang J,Liu A,Su Y,Xia Y
Tue Aug 09 00:00:00 EDT 2022
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Frontiers in pharmacology
Fan H,Hao X,Gao Y,Yang J,Liu A,Su Y,Xia Y
Tue Aug 09 00:00:00 EDT 2022
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Frontiers in pharmacology
Fan H,Hao X,Gao Y,Yang J,Liu A,Su Y,Xia Y
Tue Aug 09 00:00:00 EDT 2022
Andrographolide protects bone marrow mesenchymal stem cells against glucose and serum deprivation under hypoxia via the NRF2 signaling pathway.
Stem cell research & therapy
Sun Y,Xu H,Tan B,Yi Q,Liu H,Chen T,Xiang H,Wang R,Xie Q,Tian J,Zhu J
Mon Jul 18 00:00:00 EDT 2022
Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.
British journal of pharmacology
Lou J,Zhang H,Qi J,Xu Y,Wang X,Jiang J,Hu X,Ni L,Cai Y,Wang X,Gao W,Xiao J,Zhou K
Sat Jan 01 00:00:00 EST 2022
Protective Mechanism of Electroacupuncture on Peripheral Neurotoxicity Induced by Oxaliplatin in Rats.
Chinese journal of integrative medicine
Wang FJ,Shi S,Wang YQ,Wang K,Fan SD,Zhang YN,Feng CC,Ju ZY
Thu Sep 01 00:00:00 EDT 2022
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Ecotoxicology and environmental safety
Zhao H,Zhu Y,Zhao Y,Wang T,Li H,Yang J,Cheng X,Wang J,Wang J
Thu Dec 01 00:00:00 EST 2022
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Ecotoxicology and environmental safety
Zhao H,Zhu Y,Zhao Y,Wang T,Li H,Yang J,Cheng X,Wang J,Wang J
Thu Dec 01 00:00:00 EST 2022
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Food science & nutrition
Cui J,Zong W,Zhao N,Yuan R
Mon Aug 01 00:00:00 EDT 2022
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Biochemical pharmacology
Yang W,Tao K,Zhang P,Chen X,Sun X,Li R
Sat Jan 01 00:00:00 EST 2022
Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury.
Journal of controlled release : official journal of the Controlled Release Society
Zhao R,Wang L,Wang T,Xian P,Wang H,Long Q
Sun May 01 00:00:00 EDT 2022
Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway.
European journal of pharmacology
Wang L,Zeng YQ,Gu JH,Song R,Cang PH,Xu YX,Shao XX,Pu LJ,Luo HY,Zhou XF
Tue Apr 05 00:00:00 EDT 2022
Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts.
Cells
Li S,Yang J,Sun J,Chen M
Mon Dec 12 00:00:00 EST 2022
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway.
Journal of neuroinflammation
Dang R,Wang M,Li X,Wang H,Liu L,Wu Q,Zhao J,Ji P,Zhong L,Licinio J,Xie P
Mon Feb 07 00:00:00 EST 2022
Hatched Eggshell Membrane Can Be a Novel Source of Antioxidant Hydrolysates to Protect against H2O2-Induced Oxidative Stress in Human Chondrocytes.
Antioxidants (Basel, Switzerland)
Zhu L,Ma M,Ahn DU,Guyonnet V,Wang L,Zheng Y,He Q,Xiong H,Huang X
Fri Dec 09 00:00:00 EST 2022
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Brain research bulletin
Zhou Y,Peng L,Li Y,Zhao Y
Sat Jan 01 00:00:00 EST 2022
The Nrf2 inhibitor brusatol synergistically enhances the cytotoxic effect of lapatinib in HER2-positive cancers.
Heliyon
Tian Z,Yang Y,Wu H,Chen Y,Jia H,Zhu L,He R,Jin Y,Zhou B,Ge C,Sun Y,Yang Y
Mon Aug 01 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 EDT 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 EDT 2022
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Aug 06 00:00:00 EDT 2022
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Journal of animal science and biotechnology
Tian S,Wang J,Gao R,Wang J,Zhu W
Fri Jun 03 00:00:00 EDT 2022
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R-/-) Mice.
BioMed research international
Li W,Zhang H,Zhang L,Zhang T,Ding H
Tue Jul 19 00:00:00 EDT 2022
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R-/-) Mice.
BioMed research international
Li W,Zhang H,Zhang L,Zhang T,Ding H
Tue Jul 19 00:00:00 EDT 2022
p-TAK1 acts as a switch between myoblast proliferation phase and differentiation phase in mdx mice via regulating HO-1 expression.
European journal of pharmacology
Fan S,Huang X,Tong H,Hong H,Lai Z,Hu W,Liu X,Zhang L,Jiang Z,Yu Q
Sat Oct 15 00:00:00 EDT 2022
Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo.
Cell death & disease
Wang G,Wang Y,Yang Q,Xu C,Zheng Y,Wang L,Wu J,Zeng M,Luo M
Mon Jan 10 00:00:00 EST 2022
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
Journal of the science of food and agriculture
Zhao W,Peng D,Li W,Chen S,Liu B,Huang P,Wu J,Du B,Li P
Thu Dec 01 00:00:00 EST 2022
Novel Probiotic Lactic Acid Bacteria Were Identified from Healthy Infant Feces and Exhibited Anti-Inflammatory Capacities.
Antioxidants (Basel, Switzerland)
Li B,Pan LL,Sun J
Fri Jun 24 00:00:00 EDT 2022
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6.
Acta pharmaceutica Sinica. B
Liao L,Dang W,Lin T,Yu J,Liu T,Li W,Xiao S,Feng L,Huang J,Fu R,Li J,Liu L,Wang M,Tao H,Jiang H,Chen K,Diao X,Zhou B,Shen X,Luo C
Tue Nov 01 00:00:00 EDT 2022
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H2O2-induced BV-2 microglial cells injury.
Bioorganic chemistry
Wang Y,Zhu M,Liang J,Zhang N,Sun D,Li H,Chen L
Tue Nov 01 00:00:00 EDT 2022
Co-Treatment With Resveratrol and FGF1 Protects Against Acute Liver Toxicity After Doxorubicin Treatment via the AMPK/NRF2 Pathway.
Frontiers in pharmacology
Xu X,Liu Q,Li J,Xiao M,Gao T,Zhang X,Lu G,Wang J,Guo Y,Wen P,Gu J
Sat Sep 17 00:00:00 EDT 2022
Co-Treatment With Resveratrol and FGF1 Protects Against Acute Liver Toxicity After Doxorubicin Treatment via the AMPK/NRF2 Pathway.
Frontiers in pharmacology
Xu X,Liu Q,Li J,Xiao M,Gao T,Zhang X,Lu G,Wang J,Guo Y,Wen P,Gu J
Sat Sep 17 00:00:00 EDT 2022
Cyclo(-Phe-Phe) alleviates chick embryo liver injury via activating the Nrf2 pathway.
Food & function
Zhang QY,Han SC,Huang RP,Jiang MY,Yan CY,Li XY,Zhan YJ,Li XM,Li YF,Kurihara H,Tan RR,Li WX,He RR
Mon Jul 04 00:00:00 EDT 2022
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang J,Zhang L,Cao H,Shi X,Zhang X,Gao Z,Ikeda K,Yan T,Jia Y,Xu F
Sun May 01 00:00:00 EDT 2022
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Journal of natural products
Hao X,Fan H,Yang J,Tang J,Zhou J,Zhao Y,Huang L,Xia Y
Fri Aug 26 00:00:00 EDT 2022
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Journal of natural products
Hao X,Fan H,Yang J,Tang J,Zhou J,Zhao Y,Huang L,Xia Y
Fri Aug 26 00:00:00 EDT 2022
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Journal of natural products
Hao X,Fan H,Yang J,Tang J,Zhou J,Zhao Y,Huang L,Xia Y
Fri Aug 26 00:00:00 EDT 2022
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Journal of natural products
Hao X,Fan H,Yang J,Tang J,Zhou J,Zhao Y,Huang L,Xia Y
Fri Aug 26 00:00:00 EDT 2022
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Journal of animal science
Yu G,Ji S,Yun Y,Cheng K,Zhang H,Jia P,Wang T,Zhang L
Fri Jul 01 00:00:00 EDT 2022
Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway.
Nutrients
Lu G,Liu Q,Gao T,Li J,Zhang J,Chen O,Cao C,Mao M,Xiao M,Zhang X,Wang J,Guo Y,Tang Y,Gu J
Tue Sep 27 00:00:00 EDT 2022
Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway.
Nutrients
Lu G,Liu Q,Gao T,Li J,Zhang J,Chen O,Cao C,Mao M,Xiao M,Zhang X,Wang J,Guo Y,Tang Y,Gu J
Tue Sep 27 00:00:00 EDT 2022
Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway.
Nutrients
Lu G,Liu Q,Gao T,Li J,Zhang J,Chen O,Cao C,Mao M,Xiao M,Zhang X,Wang J,Guo Y,Tang Y,Gu J
Tue Sep 27 00:00:00 EDT 2022
Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway.
Nutrients
Lu G,Liu Q,Gao T,Li J,Zhang J,Chen O,Cao C,Mao M,Xiao M,Zhang X,Wang J,Guo Y,Tang Y,Gu J
Tue Sep 27 00:00:00 EDT 2022
Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis.
Journal of translational medicine
Kong K,Chang Y,Qiao H,Zhao C,Chen X,Rong K,Zhang P,Jin M,Zhang J,Li H,Zhai Z
Sat Nov 26 00:00:00 EST 2022
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang B,Wan S,Liu H,Qiu Q,Chen H,Chen Z,Wang L,Liu X
Wed Oct 26 00:00:00 EDT 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Journal of agricultural and food chemistry
Zhao Y,Zhang R,Wang Z,Chen Z,Wang G,Guan S,Lu J
Wed Oct 12 00:00:00 EDT 2022
An auto-photoacoustic melanin-based drug delivery nano-platform for self-monitoring of acute kidney injury therapy via a triple-collaborative strategy.
Acta biomaterialia
Zhao X,Sun J,Dong J,Guo C,Cai W,Han J,Shen H,Lv S,Zhang R
Fri Jul 15 00:00:00 EDT 2022
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Frontiers in nutrition
Li N,Wen L,Yu Z,Li T,Wang T,Qiao M,Song L,Huang X
Sat Dec 03 00:00:00 EST 2022
p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signaling.
PLoS pathogens
Ma C,Li Y,Zong Y,Velkov T,Wang C,Yang X,Zhang M,Jiang Z,Sun H,Tong Q,Sun H,Pu J,Iqbal M,Liu J,Dai C,Sun Y
Tue Feb 01 00:00:00 EST 2022
TUG1/MAZ/FTH1 Axis Attenuates the Antiglioma Effect of Dihydroartemisinin by Inhibiting Ferroptosis.
Oxidative medicine and cellular longevity
Gong H,Gao M,Lin Y,Liu J,Hu Z,Liu J
Wed Sep 28 00:00:00 EDT 2022
Phenotypic characterization of Cdkl5-knockdown neurons establishes elongated cilia as a functional assay for CDKL5 Deficiency Disorder.
Neuroscience research
Di Nardo A,Rühmkorf A,Award P,Brennecke A,Fagiolini M,Sahin M
Tue Mar 01 00:00:00 EST 2022
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury.
Cell death discovery
He R,Liu B,Xiong R,Geng B,Meng H,Lin W,Hao B,Zhang L,Wang W,Jiang W,Li N,Geng Q
Wed Feb 02 00:00:00 EST 2022
Discovery of Therapeutic Candidates for Diabetic Retinopathy Based on Molecular Switch Analysis: Application of a Systematic Process.
Oxidative medicine and cellular longevity
Ren Y,Liu Y,Liu K,Huo X,Liu C,Zhang Y
Fri Mar 04 00:00:00 EST 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
Liang P,Wang L,Yang S,Pan X,Li J,Zhang Y,Liang Y,Li J,Zhou B
Wed Nov 30 00:00:00 EST 2022
Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Fan H,Tu T,Zhang X,Yang Q,Liu G,Zhang T,Bao Y,Lu Y,Dong Z,Dong J,Zhao P
Sat Jan 01 00:00:00 EST 2022
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.
European journal of pharmacology
Zhang S,Pan C,Shang Q,Wang W,Hu T,Liu P,Chen S,Wang J,Fang Q
Tue Feb 15 00:00:00 EST 2022
Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway.
Frontiers in pharmacology
Hu X,Li C,Wang Q,Wei Z,Chen T,Wang Y,Li Y
Sat Jul 16 00:00:00 EDT 2022
Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis.
Molecules (Basel, Switzerland)
Yue L,Yang YR,Ma WX,Wang HY,Fan QW,Wang YY,Li C,Wang J,Hu ZM,Wang XF,Li FH,Liu MM,Jin J,Shi C,Wen JG
Mon Dec 05 00:00:00 EST 2022
Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis.
Molecules (Basel, Switzerland)
Yue L,Yang YR,Ma WX,Wang HY,Fan QW,Wang YY,Li C,Wang J,Hu ZM,Wang XF,Li FH,Liu MM,Jin J,Shi C,Wen JG
Mon Dec 05 00:00:00 EST 2022
The dual role of p62 in ferroptosis of glioblastoma according to p53 status.
Cell & bioscience
Yuan F,Sun Q,Zhang S,Ye L,Xu Y,Deng G,Xu Z,Zhang S,Liu B,Chen Q
Fri Feb 25 00:00:00 EST 2022
Collagen peptides from Acaudina molpadioides prevent CCl4 -induced liver injury via Keap1/Nrf2-ARE, PI3K/AKT, and MAPKs pathways.
Journal of food science
Li J,Li Y,Lin S,Zhao W,Chen Y,Jin H
Sun May 01 00:00:00 EDT 2022
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease.
International journal of molecular medicine
Lin F,Xu L,Yuan R,Han S,Xie J,Jiang K,Li B,Yu W,Rao T,Zhou X,Cheng F
Tue Mar 01 00:00:00 EST 2022
Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.
Frontiers in pharmacology
Tang TL,Yang Y,Guo L,Xia S,Zhang B,Yan M
Fri Nov 18 00:00:00 EST 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection.
Pharmacological research
Chen Y,Yi X,Huo B,He Y,Guo X,Zhang Z,Zhong X,Feng X,Fang ZM,Zhu XH,Wei X,Jiang DS
Tue Mar 01 00:00:00 EST 2022
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection.
Pharmacological research
Chen Y,Yi X,Huo B,He Y,Guo X,Zhang Z,Zhong X,Feng X,Fang ZM,Zhu XH,Wei X,Jiang DS
Tue Mar 01 00:00:00 EST 2022
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway.
Frontiers in pharmacology
Qi S,Zhang X,Fu Z,Pi A,Shi F,Fan Y,Zhang J,Xiao T,Shang D,Lin M,Gao N,Chang J,Gao Y
Tue Aug 09 00:00:00 EDT 2022
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Chemical biology & drug design
Zhu W,Tang H,Cao L,Zhang J,Li J,Ma D,Guo C
Fri Jul 01 00:00:00 EDT 2022
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Frontiers in pharmacology
Guo Z,Lin J,Sun K,Guo J,Yao X,Wang G,Hou L,Xu J,Guo J,Guo F
Tue May 30 00:00:00 EDT 2023
Targeting NRF2 Sensitizes Esophageal Adenocarcinoma Cells to Cisplatin through Induction of Ferroptosis and Apoptosis.
Antioxidants (Basel, Switzerland)
Ballout F,Lu H,Chen Z,Hu T,Chen L,Washington MK,El-Rifai W,Peng D
Wed Sep 21 00:00:00 EDT 2022
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Free radical biology & medicine
Peng X,Su S,Zeng J,Xie K,Yang X,Xian G,Xiao Z,Zhu P,Zheng S,Xu D,Zeng Q
Mon Aug 01 00:00:00 EDT 2022
Berberine prevents lethal EV71 neurological infection in newborn mice.
Frontiers in pharmacology
Cui G,Wang H,Yang C,Zhou X,Wang J,Wang T,Ma T
Fri Nov 18 00:00:00 EST 2022
Targeting PCSK9 in Liver Cancer Cells Triggers Metabolic Exhaustion and Cell Death by Ferroptosis.
Cells
Alannan M,Fatrouni H,Trézéguet V,Dittrich-Domergue F,Moreau P,Siegfried G,Liet B,Khatib AM,Grosset CF,Badran B,Fayyad-Kazan H,Merched AJ
Fri Dec 23 00:00:00 EST 2022
Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways.
Oxidative medicine and cellular longevity
Li L,Xuan Y,Zhu B,Wang X,Tian X,Zhao L,Wang Y,Jiang X,Wen N
Tue Dec 13 00:00:00 EST 2022
Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway.
ACS biomaterials science & engineering
Guo J,Yang X,Chen J,Wang C,Kang Y,Jiang T,Chen M,Li W,Zhou C,Chen Z
Mon Oct 10 00:00:00 EDT 2022
Relationship between Neuroprotective Effects and Structure of Procyanidins.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Apr 02 00:00:00 EDT 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 EDT 2022
Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury.
Aging
Gong F,Ge T,Liu J,Xiao J,Wu X,Wang H,Zhu Y,Xia D,Hu B
Sun Apr 10 00:00:00 EDT 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Journal of agricultural and food chemistry
Du L,Hao YM,Yang YH,Zheng Y,Wu ZJ,Zhou MQ,Wang BZ,Wang YM,Wu H,Su GH
Wed Mar 09 00:00:00 EST 2022
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling.
Journal of nanobiotechnology
Liu J,Wu Z,Liu Y,Zhan Z,Yang L,Wang C,Jiang Q,Ran H,Li P,Wang Z
Fri May 06 00:00:00 EDT 2022
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling.
Journal of nanobiotechnology
Liu J,Wu Z,Liu Y,Zhan Z,Yang L,Wang C,Jiang Q,Ran H,Li P,Wang Z
Fri May 06 00:00:00 EDT 2022
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Journal of applied toxicology : JAT
Liu YP,Yuan XY,Li XY,Wang Y,Sun ZB,Deng WH,Lei YD,Huang L,Jiang TY,Zhang ZH
Tue Feb 01 00:00:00 EST 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Frontiers in pharmacology
Ma T,Jia L,Zhao J,Lv L,Yu Y,Ruan H,Song X,Chen H,Li X,Zhang J,Gao L
Fri Nov 18 00:00:00 EST 2022
Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Dai C,Zhang Q,Shen L,Sharma G,Jiang H,Wang Z,Shen J
Sat Jul 30 00:00:00 EDT 2022
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
Stem cell research & therapy
Wang K,Zhou C,Li L,Dai C,Wang Z,Zhang W,Xu J,Zhu Y,Pan Z
Fri Aug 19 00:00:00 EDT 2022
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Journal of dental sciences
Xi X,Li ZX,Zhao Y,Liu H,Chen S,Liu DX
Fri Apr 01 00:00:00 EDT 2022
Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling.
Antioxidants (Basel, Switzerland)
Wang K,Tang Y,Wu X,Liang H,Chen D,Yu B,He J,Mao X,Huang Z,Yan H,Wu A,Luo Y,Zheng P,Yu J,Wang H,Luo J
Sun Sep 18 00:00:00 EDT 2022
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li S,Ma Y,Ye S,Su Y,Hu D,Xiao F
Wed Jun 01 00:00:00 EDT 2022
Chronic exposure to propylparaben at the humanly relevant dose triggers ovarian aging in adult mice.
Ecotoxicology and environmental safety
Yan W,Li M,Guo Q,Li X,Zhou S,Dai J,Zhang J,Wu M,Tang W,Wen J,Xue L,Jin Y,Luo A,Wang S
Fri Apr 15 00:00:00 EDT 2022
Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.
International immunopharmacology
Liu L,Shi Q,Wang K,Qian Y,Zhou L,Bellusci S,Chen C,Dong N
Thu Dec 01 00:00:00 EST 2022
Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4.
Stem cell research & therapy
Sun F,Sun Y,Zhu J,Wang X,Ji C,Zhang J,Chen S,Yu Y,Xu W,Qian H
Fri Jul 15 00:00:00 EDT 2022
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Biochemical pharmacology
Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F
Tue Mar 01 00:00:00 EST 2022
Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response.
Antioxidants (Basel, Switzerland)
De Backer J,Maric D,Zuhra K,Bogaerts A,Szabo C,Vanden Berghe W,Hoogewijs D
Wed Aug 10 00:00:00 EDT 2022
Neuron derived fractalkine promotes microglia to absorb hematoma via CD163/HO-1 after intracerebral hemorrhage.
Cellular and molecular life sciences : CMLS
You M,Long C,Wan Y,Guo H,Shen J,Li M,He Q,Hu B
Thu Apr 07 00:00:00 EDT 2022
18β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice.
Scientific reports
Liu J,Xu Y,Yan M,Yu Y,Guo Y
Thu Feb 24 00:00:00 EST 2022
Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury.
International immunopharmacology
Qiu W,An S,Wang T,Li J,Yu B,Zeng Z,Chen Z,Lin B,Lin X,Gao Y
Tue Nov 01 00:00:00 EDT 2022
Transcriptomic analysis and laboratory experiments reveal potential critical genes and regulatory mechanisms in sepsis-associated acute kidney injury.
Annals of translational medicine
Liu B,Ao S,Tan F,Ma W,Liu H,Liang H,Yang X,Chi X
Fri Jul 01 00:00:00 EDT 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 EDT 2022
Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways.
European journal of pharmacology
Zhang L,Zhu XZ,Badamjav R,Zhang JZ,Kou JP,Yu BY,Li F
Tue Feb 15 00:00:00 EST 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Gao Y,Hu M,Niu X,Li M,Xu L,Xiao Y,Zhang J,Wang H,Li L,Chu B,Lv P
Tue Dec 13 00:00:00 EST 2022
Preparation of curcumin-loaded cochleates: characterisation, stability and antioxidant properties.
Food & function
Chen L,Yue B,Liu Z,Luo Y,Ni L,Shen W,Zhou Z,Ge X
Mon Oct 31 00:00:00 EDT 2022
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Toxicology
Lei S,Feng Y,Huang P,Chen B,Bao K,Wu Q,Zhang H,Huang X
Fri Jul 01 00:00:00 EDT 2022
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
Frontiers in pharmacology
Shi H,Hou B,Li H,Zhou H,Du B
Fri Mar 11 00:00:00 EST 2022
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Molecules (Basel, Switzerland)
Zhang D,Li X,He X,Xing Y,Jiang B,Xiu Z,Bao Y,Dong Y
Sat Nov 12 00:00:00 EST 2022
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Free radical biology & medicine
Li T,Geng Z,Zhang J,Xu L,Zhu X
Sun Nov 20 00:00:00 EST 2022
Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway.
BMC complementary medicine and therapies
Chen Z,Liu H,Zhao X,Mamateli S,Liu C,Wang L,Yu J,Liu Y,Cai J,Qiao T
Thu Jul 07 00:00:00 EDT 2022
Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.
Bioorganic & medicinal chemistry
Wang W,Xiong L,Li Y,Song Z,Sun D,Li H,Chen L
Tue Feb 15 00:00:00 EST 2022
4-Ethylguaiacol Modulates Neuroinflammation and Promotes Heme Oxygenase-1 Expression to Ameliorate Brain Injury in Ischemic Stroke.
Frontiers in immunology
Weng WT,Kuo PC,Scofield BA,Paraiso HC,Brown DA,Yu IC,Yen JH
Fri Jul 22 00:00:00 EDT 2022
4-Ethylguaiacol Modulates Neuroinflammation and Promotes Heme Oxygenase-1 Expression to Ameliorate Brain Injury in Ischemic Stroke.
Frontiers in immunology
Weng WT,Kuo PC,Scofield BA,Paraiso HC,Brown DA,Yu IC,Yen JH
Fri Jul 22 00:00:00 EDT 2022
Cytoglobin inhibits non-thermal plasma-induced apoptosis in melanoma cells through regulation of the NRF2-mediated antioxidant response.
Redox biology
De Backer J,Lin A,Berghe WV,Bogaerts A,Hoogewijs D
Thu Sep 01 00:00:00 EDT 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 EDT 2022
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhong T,Li M,Wu H,Wang D,Liu J,Xu Y,Fan Y
Wed Jun 01 00:00:00 EDT 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 EST 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Food & function
Zhang X,Zhang B,Li L,Li X,Zhang J,Chen G
Mon Aug 01 00:00:00 EDT 2022
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zhou W,Dong G,Gao G,He Z,Xu J,Aziz S,Ma L,Zhao W
Mon Aug 01 00:00:00 EDT 2022
Role of caspase-8 and/or -9 as biomarkers that can distinguish the potential to cause toxic- and immune related-adverse event, for the progress of acetaminophen-induced liver injury.
Life sciences
Noda T,Kato R,Hattori T,Furukawa Y,Ijiri Y,Tanaka K
Fri Apr 01 00:00:00 EDT 2022
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels.
European journal of pharmacology
Han Y,Li C,Zhang P,Yang X,Min J,Wu Q,Xie Y,Jin D,Wang Z,Shao F,Quan H
Tue Apr 05 00:00:00 EDT 2022
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study.
Frontiers in bioengineering and biotechnology
Jing S,Wan J,Wang T,He Z,Ding Q,Sheng G,Wang S,Zhao H,Zhu Z,Wu H,Li W
Fri Dec 23 00:00:00 EST 2022
Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.
Antioxidants (Basel, Switzerland)
Liu S,Wen X,Huang Q,Zhu M,Lu J
Fri Jun 10 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 EDT 2022
Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling.
BMJ open diabetes research & care
Zhang W,Dun Y,You B,Qiu L,Ripley-Gonzalez JW,Cheng J,Fu S,Li C,Liu S
Tue Mar 01 00:00:00 EST 2022
Mitigation of doxorubicin-induced cardiotoxicity with an H2O2-Activated, H2S-Donating hybrid prodrug.
Redox biology
Hu Q,Yammani RD,Brown-Harding H,Soto-Pantoja DR,Poole LB,Lukesh JC
Fri Jul 01 00:00:00 EDT 2022
Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Yang Y,He B,Zhang X,Yang R,Xia X,Chen L,Li R,Shen Z,Chen P
Thu Mar 17 00:00:00 EDT 2022
Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Guan L,Mao Z,Yang S,Wu G,Chen Y,Yin L,Qi Y,Han L,Xu L
Mon Aug 01 00:00:00 EDT 2022
Protective effects of di-caffeoylquinic acids from Artemisia selengensis Turcz leaves against monosodium urate-induced inflammation via the modulation of NLRP3 inflammasome and Nrf2 signaling pathway in THP-1 macrophages.
Journal of food biochemistry
Cao W,Wu T,Liang F,Fang Y,Cheng Y,Pan S,Xu X
Thu Sep 01 00:00:00 EDT 2022
The Attenuation of Chronic Ulcerative Colitis by (R)-salbutamol in Repeated DSS-Induced Mice.
Oxidative medicine and cellular longevity
Deng L,Guo H,Wang S,Liu X,Lin Y,Zhang R,Tan W
Fri Mar 18 00:00:00 EDT 2022
Fibroblast Growth Factor 19 Improves LPS-Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice.
Oxidative medicine and cellular longevity
Liu T,Tang X,Cui Y,Xiong X,Xu Y,Hu S,Feng S,Shao L,Ren Y,Miao H,Zhang H,Zhu X,Zhang Y,Wang C
Tue Jul 19 00:00:00 EDT 2022
Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis.
Biomolecules
Ye Q,Taleb SJ,Wang H,Parinandi NL,Kass DJ,Rojas M,Wang C,Ma Q,Zhao J,Zhao Y
Fri Oct 21 00:00:00 EDT 2022
Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis.
Biomolecules
Ye Q,Taleb SJ,Wang H,Parinandi NL,Kass DJ,Rojas M,Wang C,Ma Q,Zhao J,Zhao Y
Fri Oct 21 00:00:00 EDT 2022
Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis.
Biomolecules
Ye Q,Taleb SJ,Wang H,Parinandi NL,Kass DJ,Rojas M,Wang C,Ma Q,Zhao J,Zhao Y
Fri Oct 21 00:00:00 EDT 2022
Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis.
Biomolecules
Ye Q,Taleb SJ,Wang H,Parinandi NL,Kass DJ,Rojas M,Wang C,Ma Q,Zhao J,Zhao Y
Fri Oct 21 00:00:00 EDT 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Oxidative medicine and cellular longevity
Xu C,Ni S,Xu N,Yin G,Yu Y,Zhou B,Zhao G,Wang L,Zhu R,Jiang S,Wang Y
Mon Dec 12 00:00:00 EST 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
Trans-anethole Ameliorates Intestinal Injury Through Activation of Nrf2 Signaling Pathway in Subclinical Necrotic Enteritis-Induced Broilers.
Frontiers in veterinary science
Yu C,Tong Y,Li Q,Wang T,Yang Z
Sat May 07 00:00:00 EDT 2022
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.
Frontiers in pharmacology
Han D,Wang F,Wang B,Qiao Z,Cui X,Zhang Y,Jiang Q,Liu M,Shangguan J,Zheng X,Bai Y,Du C,Shen D
Wed Feb 23 00:00:00 EST 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway.
International immunopharmacology
Bai X,Zhu Y,Jie J,Li D,Song L,Luo J
Fri Jul 01 00:00:00 EDT 2022
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Fundamental & clinical pharmacology
Xu L,Gao Y,Hu M,Dong Y,Xu J,Zhang J,Lv P
Sat Oct 01 00:00:00 EDT 2022
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Free radical research
Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C
Wed Nov 30 00:00:00 EST 2022
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury.
Free radical research
Zheng J,Wang Y,Wang Z,Chen W,Luo M,Zhang C,Wang Y,Chen L,Wu F,Yang W,Yang Z,Wang Y,Shi C
Wed Nov 30 00:00:00 EST 2022
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Oxidative medicine and cellular longevity
Wang L,Wang J
Fri Dec 30 00:00:00 EST 2022
Gandouling Mitigates CuSO4-Induced Heart Injury in Rats.
Animals : an open access journal from MDPI
Fang S,Yang W,Zhang K,Peng C
Sat Oct 08 00:00:00 EDT 2022
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
Journal of Asian natural products research
Yang R,Shen YJ,Chen M,Zhao JY,Chen SH,Zhang W,Song JK,Li L,Du GH
Tue Mar 01 00:00:00 EST 2022
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Environmental toxicology
Guan S,Zhang R,Zhao Y,Meng Z,Lu J
Sat Oct 01 00:00:00 EDT 2022
Relief Effects of Icariin on Inflammation-Induced Decrease of Tight Junctions in Intestinal Epithelial Cells.
Frontiers in pharmacology
Li Y,Liu J,Pongkorpsakol P,Xiong Z,Li L,Jiang X,Zhao H,Yuan D,Zhang C,Guo Y,Dun Y
Sat Jul 16 00:00:00 EDT 2022
Hedyotis diffusa injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Huang F,Pang J,Xu L,Niu W,Zhang Y,Li S,Li X
Thu Sep 01 00:00:00 EDT 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 EDT 2022
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Journal of ethnopharmacology
Zhang XG,Liu AX,Zhang YX,Zhou MY,Li XY,Fu MH,Pan YP,Xu J,Zhang JQ
Thu Sep 15 00:00:00 EDT 2022
2-Fluorofucose Attenuates Hydrogen Peroxide-Induced Oxidative Stress in HepG2 Cells via Nrf2/keap1 and NF-κB Signaling Pathways.
Life (Basel, Switzerland)
Tu M,Fan X,Shi J,Jing S,Xu X,Wang Y
Fri Mar 11 00:00:00 EST 2022
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Bioengineered
Zhu W,Tang H,Li J,Guedes RM,Cao L,Guo C
Fri Apr 01 00:00:00 EDT 2022
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Die Pharmazie
Kato R,Ijiri Y
Tue Feb 01 00:00:00 EST 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 EDT 2022
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Oxidative medicine and cellular longevity
Chen P,Yang J,Wu N,Han B,Kastelic JP,Gao J
Fri Mar 18 00:00:00 EDT 2022
Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells.
International journal of molecular sciences
Wang H,Hao W,Yang L,Li T,Zhao C,Yan P,Wei S
Thu Jul 14 00:00:00 EDT 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling.
Molecules (Basel, Switzerland)
Cheng S,Jia H,Zhang Y,Zhou J,Chen X,Wu L,Wang J
Mon Dec 05 00:00:00 EST 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Drug design, development and therapy
Wang J,Zhang Y,Zhang M,Sun S,Zhong Y,Han L,Xu Y,Wan D,Zhang J,Zhu H
Mon Mar 28 00:00:00 EDT 2022
Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2.
Molecules (Basel, Switzerland)
Zou L,Bao W,Gao Y,Chen M,Wu Y,Wang S,Li C,Zhang J,Zhang D,Wang Q,Zhu A
Sun Oct 16 00:00:00 EDT 2022
Trypsin inhibitor LH011 inhibited DSS-induced mice colitis via alleviating inflammation and oxidative stress.
Frontiers in pharmacology
Jia Z,Wang P,Xu Y,Feng G,Wang Q,He X,Song Y,Liu P,Chen J
Sat Oct 15 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Ecotoxicology and environmental safety
Xue L,Li X,Zhu X,Zhang J,Zhou S,Tang W,Chen D,Chen Y,Dai J,Wu M,Wu M,Wang S
Thu Sep 01 00:00:00 EDT 2022
HMGB2 causes photoreceptor death via down-regulating Nrf2/HO-1 and up-regulating NF-κB/NLRP3 signaling pathways in light-induced retinal degeneration model.
Free radical biology & medicine
Zhang Y,Zhao Z,Zhao X,Xie H,Zhang C,Sun X,Zhang J
Tue Mar 01 00:00:00 EST 2022
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Environmental toxicology
Zhai X,Dai T,Chi Z,Zhao Z,Wu G,Yang S,Dong D
Wed Jun 01 00:00:00 EDT 2022
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Toxics
Wang P,Liu D,Yan S,Liang Y,Cui J,Guo L,Ren S,Chen P
Fri Jul 29 00:00:00 EDT 2022
Scorias spongiosa Polysaccharides Promote the Antioxidant and Anti-Inflammatory Capacity and Its Effect on Intestinal Microbiota in Mice.
Frontiers in microbiology
Xu Y,Zhang Z,Feng H,Tang J,Peng W,Chen Y,Zhou J,Wang Y
Sat Apr 02 00:00:00 EDT 2022
Activated AMP-activated protein kinase prevents hepatic steatosis, oxidative stress and inflammation in primary chicken hepatocytes.
Frontiers in physiology
Yao Y,Li L,Wang H,Yang Y,Ma H
Wed Sep 28 00:00:00 EDT 2022
Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2.
Redox biology
Wang A J,Tang Y,Zhang J,Wang B J,Xiao M,Lu G,Li J,Liu Q,Guo Y,Gu J
Wed Jun 01 00:00:00 EDT 2022
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Journal of nanobiotechnology
Wu L,Tian X,Zuo H,Zheng W,Li X,Yuan M,Tian X,Song H
Fri Apr 22 00:00:00 EDT 2022
Protective effect of rutin against diabetes-associated cognitive decline in rats.
Pakistan journal of pharmaceutical sciences
Xianchu L,Huan P,Kang L,Beiwang D,Ming L
Sun May 01 00:00:00 EDT 2022
JMJD8 Functions as a Novel AKT1 Lysine Demethylase.
International journal of molecular sciences
Wang Y,Zhang Y,Li Z,Wang J
Tue Dec 27 00:00:00 EST 2022
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang Z,Yao M,Jiang L,Wang L,Yang Y,Wang Q,Qian X,Zhao Y,Qian J
Sat Oct 01 00:00:00 EDT 2022
Tanshinone IIA Regulates Keap1/Nrf2 Signal Pathway by Activating Sestrin2 to Restrain Pulmonary Fibrosis.
The American journal of Chinese medicine
Li H,Wu M,Guo C,Zhai R,Chen J
Thu Dec 29 00:00:00 EST 2022
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Antioxidants (Basel, Switzerland)
Zhao H,Xian G,Zeng J,Zhong G,An D,Peng Y,Hu D,Lin Y,Li J,Su S,Ning Y,Xu D,Zeng Q
Mon Oct 24 00:00:00 EDT 2022
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Antioxidants (Basel, Switzerland)
Zhao H,Xian G,Zeng J,Zhong G,An D,Peng Y,Hu D,Lin Y,Li J,Su S,Ning Y,Xu D,Zeng Q
Mon Oct 24 00:00:00 EDT 2022
Effects of limonin treatment on the survival of random skin flaps in mice.
Frontiers in surgery
Zhang T,Huang Q,Gan K,Zhou K,Hu K,Ding W,Jin J,Li J
Wed Feb 01 00:00:00 EST 2023
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Molecules (Basel, Switzerland)
Peng J,Cai Z,Wang Q,Zhou J,Xu J,Pan D,Chen T,Zhang G,Tao L,Chen Y,Shen X
Sat Jun 04 00:00:00 EDT 2022
Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Lin Y,Zhang Q,Xie B,Jiang H,Shen J,Tang S,Dai C
Sun Sep 18 00:00:00 EDT 2022
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Frontiers in pharmacology
Guo K,Liu R,Jing R,Wang L,Li X,Zhang K,Fu M,Ye J,Hu Z,Zhao W,Xu N
Fri Nov 18 00:00:00 EST 2022
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Bioengineered
Zhou S,Li J,Zhang X,Xiong W
Sun May 01 00:00:00 EDT 2022
Activation of the P62-Keap1-NRF2 Pathway Protects against Ferroptosis in Radiation-Induced Lung Injury.
Oxidative medicine and cellular longevity
Li X,Chen J,Yuan S,Zhuang X,Qiao T
Mon Dec 12 00:00:00 EST 2022
Amentoflavone Exerts Anti-Neuroinflammatory Effects by Inhibiting TLR4/MyD88/NF-κB and Activating Nrf2/HO-1 Pathway in Lipopolysaccharide-Induced BV2 Microglia.
Mediators of inflammation
Rong S,Yang C,Wang F,Wu Y,Sun K,Sun T,Wu Z
Fri Dec 23 00:00:00 EST 2022
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Human & experimental toxicology
Du P,Zhang X,Luo K,Li Y,Fu C,Xiao J,Xiao Q
Mon Apr 04 00:00:00 EDT 2022
A Combination therapy using an mTOR inhibitor and Honokiol effectively induces autophagy through the modulation of AXL and Rubicon in renal cancer cells and restricts renal tumor growth following organ transplantation.
Carcinogenesis
Sabarwal A,Wedel J,Liu K,Zurakowski D,Chakraborty S,Flynn E,Briscoe DM,Balan M,Pal S
Thu May 19 00:00:00 EDT 2022
Dendrobium officinale polysaccharide inhibits vascular calcification via anti-inflammatory and anti-apoptotic effects in chronic kidney disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang W,Ruan W,Wang Z
Thu Sep 01 00:00:00 EDT 2022
Aberrant expression of KDM1A inhibits ferroptosis of lung cancer cells through up-regulating c-Myc.
Scientific reports
Lu C,Cai Y,Liu W,Peng B,Liang Q,Yan Y,Liang D,Xu Z
Thu Nov 10 00:00:00 EST 2022
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
European journal of pharmacology
Zheng LY,Zou X,Wang YL,Zou M,Ma F,Wang N,Li JW,Wang MS,Hung HY,Wang Q
Wed Jan 05 00:00:00 EST 2022
Gallic acid ameliorates calcium oxalate crystal-induced renal injury via upregulation of Nrf2/HO-1 in the mouse model of stone formation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou D,Wu Y,Yan H,Shen T,Li S,Gong J,Li G,Mai H,Wang D,Tan X
Tue Nov 01 00:00:00 EDT 2022
Different cellular mechanisms from low- and high-dose zinc oxide nanoparticles-induced heart tube malformation during embryogenesis.
Nanotoxicology
Wang M,Zhang P,Li Z,Yan Y,Cheng X,Wang G,Yang X
Wed Jun 01 00:00:00 EDT 2022
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Frontiers in pharmacology
Li D,Zhao H,Xu P,Lin Q,Zhao T,Li C,Cui ZK,Tian G
Tue Aug 23 00:00:00 EDT 2022
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Frontiers in pharmacology
Li D,Zhao H,Xu P,Lin Q,Zhao T,Li C,Cui ZK,Tian G
Tue Aug 23 00:00:00 EDT 2022
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Journal of pharmacological sciences
Cui Z,Wang H,Li S,Qin T,Shi H,Ma J,Li L,Yu G,Jiang T,Li C
Sat Jan 01 00:00:00 EST 2022
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
ChemMedChem
Ye H,Ma Z,Liu L,Zhang T,Han Q,Xiang Z,Xia Y,Ke Y,Guan X,Shi Q,Ataullakhanov FI,Panteleev M
Fri Dec 16 00:00:00 EST 2022
Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis.
Bone research
Yang Y,Lin Y,Wang M,Yuan K,Wang Q,Mu P,Du J,Yu Z,Yang S,Huang K,Wang Y,Li H,Tang T
Wed Mar 09 00:00:00 EST 2022
Synthesis and biological evaluation of novel schisanhenol derivatives as potential hepatoprotective agents.
European journal of medicinal chemistry
Deng L,Cheng S,Li J,Xu X,Hao X,Fan Y,Mu S
Wed Jan 05 00:00:00 EST 2022
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway.
Free radical research
Qi Y,Fu S,Pei D,Fang Q,Xin W,Yuan X,Cao Y,Shu Q,Mi X,Luo F
Tue Feb 01 00:00:00 EST 2022
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Toxicology letters
Jin C,Min F,Zhong Y,Sun D,Luo R,Liu Q,Peng X
Tue Mar 01 00:00:00 EST 2022
Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects.
Frontiers in pharmacology
Liu Z,Tu M,Shi J,Zhou H,Meng G,Gu J,Wang Y
Tue Sep 20 00:00:00 EDT 2022
GSK 650394 Inhibits Osteoclasts Differentiation and Prevents Bone Loss via Promoting the Activities of Antioxidant Enzymes In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Jin LY,Huo SC,Guo C,Liu HY,Xu S,Li XF
Wed Sep 28 00:00:00 EDT 2022
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
The Journal of toxicological sciences
Lyu Y,Ren XK,Guo CC,Li ZF,Zheng JP
Fri Dec 02 00:00:00 EST 2022
Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis.
Antioxidants & redox signaling
Potor L,Hendrik Z,Patsalos A,Katona É,Méhes G,Póliska S,Csősz É,Kalló G,Komáromi I,Combi Z,Posta N,Sikura KÉ,Pethő D,Oros M,Vereb G,Tóth C,Gergely P,Nagy L,Balla G,Balla J
Wed Oct 20 00:00:00 EDT 2021
Protective effects of gastrodin pretreatment on mouse hepatic ischemia-reperfusion occurring through antioxidant and anti-apoptotic mechanisms.
Experimental and therapeutic medicine
Sun B,Jiang J,Zhu X,Yang D,Cui Z,Zhang Y,Zhang M,Qian Y,Liu R,Yang W
Sat May 01 00:00:00 EDT 2021
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Theranostics
Luo Q,Xian P,Wang T,Wu S,Sun T,Wang W,Wang B,Yang H,Yang Y,Wang H,Liu W,Long Q
Fri Jul 30 00:00:00 EDT 2021
Downregulated MicroRNA-327 Attenuates Oxidative Stress-Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Zheng T,Yang J,Zhang J,Yang C,Fan Z,Li Q,Zhai Y,Liu H,Yang J
Wed May 26 00:00:00 EDT 2021
Immunoresponsive gene 1 modulates the severity of brain injury in cerebral ischaemia.
Brain communications
Kuo PC,Weng WT,Scofield BA,Furnas D,Paraiso HC,Yu IC,Yen JH
Sun Sep 26 00:00:00 EDT 2021
Immunoresponsive gene 1 modulates the severity of brain injury in cerebral ischaemia.
Brain communications
Kuo PC,Weng WT,Scofield BA,Furnas D,Paraiso HC,Yu IC,Yen JH
Sun Sep 26 00:00:00 EDT 2021
Immunoresponsive gene 1 modulates the severity of brain injury in cerebral ischaemia.
Brain communications
Kuo PC,Weng WT,Scofield BA,Furnas D,Paraiso HC,Yu IC,Yen JH
Sun Sep 26 00:00:00 EDT 2021
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Journal of cellular and molecular medicine
Zhang J,Yang S,Guan H,Zhou J,Gao Y
Mon Feb 01 00:00:00 EST 2021
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Journal of agricultural and food chemistry
Zhao Y,Lu J,Mao A,Zhang R,Guan S
Wed Aug 25 00:00:00 EDT 2021
Marine algal polysaccharides alleviate aflatoxin B1-induced bursa of Fabricius injury by regulating redox and apoptotic signaling pathway in broilers.
Poultry science
Guo Y,Balasubramanian B,Zhao ZH,Liu WC
Mon Feb 01 00:00:00 EST 2021
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Pharmaceutical biology
Feng Z,Wang C,Meng Q,Wu J,Sun H
Wed Dec 01 00:00:00 EST 2021
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Journal of inflammation research
Wang H,Jiang Z,Pang Z,Qi G,Hua B,Yan Z,Yuan H
Thu Apr 21 00:00:00 EDT 2022
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Cell biochemistry and biophysics
Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J
Tue Jun 01 00:00:00 EDT 2021
Role of MicroRNA-155 in Triptolide-induced hepatotoxicity via the Nrf2-Dependent pathway.
Journal of ethnopharmacology
Li Y,Guo L,Hou Z,Gong H,Yan M,Zhang B
Sun Dec 05 00:00:00 EST 2021
Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway.
Frontiers in cardiovascular medicine
Liao ZQ,Jiang YN,Su ZL,Bi HL,Li JT,Li CL,Yang XL,Zhang Y,Xie X
Tue Jan 25 00:00:00 EST 2022
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Journal of diabetes and its complications
Chen N,Song S,Yang Z,Wu M,Mu L,Zhou T,Shi Y
Wed Dec 01 00:00:00 EST 2021
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Journal of diabetes and its complications
Chen N,Song S,Yang Z,Wu M,Mu L,Zhou T,Shi Y
Wed Dec 01 00:00:00 EST 2021
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Phytochemistry
Song Z,Gao C,Jiang Q,Xu J,Xiong L,Liu K,Sun D,Li H,Chen L
Wed Dec 01 00:00:00 EST 2021
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Journal of animal science
Yun Y,Ji S,Yu G,Jia P,Niu Y,Zhang H,Zhang X,Wang T,Zhang L
Fri Oct 01 00:00:00 EDT 2021
Autophagy deficiency exacerbates acute lung injury induced by copper oxide nanoparticles.
Journal of nanobiotechnology
Xiao J,Tu B,Zhou X,Jiang X,Xu G,Zhang J,Qin X,Sumayyah G,Fan J,Wang B,Chen C,Zou Z
Mon May 31 00:00:00 EDT 2021
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
FEBS open bio
Huang Q,Ouyang DS,Liu Q
Sun Aug 01 00:00:00 EDT 2021
Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis.
Life sciences
Zhang J,Jiang D,Lin S,Cheng Y,Pan J,Ding W,Chen Y,Fan J
Thu Apr 01 00:00:00 EDT 2021
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Ecotoxicology and environmental safety
Hong Y,Zhou Y,Shen L,Wei Y,Long C,Fu Y,Wu H,Wang J,Wu Y,Wu S,Wei G
Mon Dec 20 00:00:00 EST 2021
Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells.
Cell metabolism
Zhu XG,Chudnovskiy A,Baudrier L,Prizer B,Liu Y,Ostendorf BN,Yamaguchi N,Arab A,Tavora B,Timson R,Heissel S,de Stanchina E,Molina H,Victora GD,Goodarzi H,Birsoy K
Tue Jan 05 00:00:00 EST 2021
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
Journal of ethnopharmacology
Lu Q,Gu W,Luo C,Wang L,Hua W,Sun Y,Tang L
Wed Feb 10 00:00:00 EST 2021
Methylcobalamin Protects Melanocytes from H2O2-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway.
Drug design, development and therapy
An R,Li D,Dong Y,She Q,Zhou T,Nie X,Pan R,Deng Y
Wed Mar 02 00:00:00 EST 2022
Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCε/ERK-mediated oxidative stress.
European journal of pharmacology
Li R,Qi Y,Yuan Q,Xu L,Gao M,Xu Y,Han X,Yin L,Liu C
Wed Sep 15 00:00:00 EDT 2021
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Biomolecules & therapeutics
Zhang Z,Zhang Q,Li F,Xin Y,Duan Z
Mon Mar 01 00:00:00 EST 2021
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Journal of cellular and molecular medicine
Li X,Wang X,Miao L,Liu Y,Lin X,Guo Y,Yuan R,Tian H
Tue Jun 01 00:00:00 EDT 2021
Myricetin protects against H2 O2 -induced oxidative damage and apoptosis in bovine mammary epithelial cells.
Journal of cellular physiology
Kan X,Liu J,Chen Y,Guo W,Xu D,Cheng J,Cao Y,Yang Z,Fu S
Thu Apr 01 00:00:00 EDT 2021
Pulmonary Exposure to Copper Oxide Nanoparticles Leads to Neurotoxicity via Oxidative Damage and Mitochondrial Dysfunction.
Neurotoxicity research
Zhou H,Yao L,Jiang X,Sumayyah G,Tu B,Cheng S,Qin X,Zhang J,Zou Z,Chen C
Sun Aug 01 00:00:00 EDT 2021
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Food & function
Xu Q,Fan Y,Loor JJ,Liang Y,Lv H,Sun X,Jia H,Xu C
Thu Jan 21 00:00:00 EST 2021
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
International journal of biological macromolecules
Liu C,Hua H,Zhu H,Cheng Y,Guo Y,Yao W,Qian H
Tue Aug 31 00:00:00 EDT 2021
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon May 17 00:00:00 EDT 2021
Cordyceps acid alleviates lung cancer in nude mice.
Journal of biochemical and molecular toxicology
Wang J,Chen H,Li W,Shan L
Mon Mar 01 00:00:00 EST 2021
The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway.
European journal of pharmacology
Guo X,Cao P,Lian X,Hu M,Zhao J,Shen W,Wang H,Yu H,Chen Y
Fri Oct 15 00:00:00 EDT 2021
A Shortage of FTH Induces ROS and Sensitizes RAS-Proficient Neuroblastoma N2A Cells to Ferroptosis.
International journal of molecular sciences
Lu R,Jiang Y,Lai X,Liu S,Sun L,Zhou ZW
Wed Aug 18 00:00:00 EDT 2021
FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Signal transduction and targeted therapy
Wang D,Yin Y,Wang S,Zhao T,Gong F,Zhao Y,Wang B,Huang Y,Cheng Z,Zhu G,Wang Z,Wang Y,Ren J,Liang G,Li X,Huang Z
Wed Mar 24 00:00:00 EDT 2021
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
Autophagy
He R,Wang Z,Cui M,Liu S,Wu W,Chen M,Wu Y,Qu Y,Lin H,Chen S,Wang B,Shao Z
Mon Nov 01 00:00:00 EDT 2021
Epigallocatechin gallate and theaflavins independently alleviate cyclophosphamide-induced ovarian damage by inhibiting the overactivation of primordial follicles and follicular atresia.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen Q,Xu Z,Li X,Du D,Wu T,Zhou S,Yan W,Wu M,Jin Y,Zhang J,Wang S
Mon Nov 01 00:00:00 EDT 2021
Design, synthesis, and evaluation of mono-carbonyl analogues of curcumin (MCACs) as potential antioxidants against periodontitis.
Journal of periodontal research
Zhao Y,Zheng Z,Zhang M,Wang Y,Hu R,Lin W,Huang C,Xu C,Wu J,Deng H
Sun Aug 01 00:00:00 EDT 2021
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Frontiers in nutrition
Zhang P,Han X,Zhang X,Zhu X
Sun May 30 00:00:00 EDT 2021
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Acta pharmaceutica Sinica. B
Gao C,Xu Y,Liang Z,Wang Y,Shang Q,Zhang S,Wang C,Ni M,Wu D,Huang Z,Pang T
Thu Jul 01 00:00:00 EDT 2021
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Human & experimental toxicology
Liu X,Li M,Zhu J,Huang W,Song J
Thu Jul 01 00:00:00 EDT 2021
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Cell death & disease
Luo W,Li J,Li Z,Lin T,Zhang L,Yang W,Mai Y,Liu R,Chen M,Dai C,Yang H,Lu J,Li H,Guan G,Huang M,Liu P,Li Z
Mon Jul 26 00:00:00 EDT 2021
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Cell death & disease
Luo W,Li J,Li Z,Lin T,Zhang L,Yang W,Mai Y,Liu R,Chen M,Dai C,Yang H,Lu J,Li H,Guan G,Huang M,Liu P,Li Z
Mon Jul 26 00:00:00 EDT 2021
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Cell death & disease
Luo W,Li J,Li Z,Lin T,Zhang L,Yang W,Mai Y,Liu R,Chen M,Dai C,Yang H,Lu J,Li H,Guan G,Huang M,Liu P,Li Z
Mon Jul 26 00:00:00 EDT 2021
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Drug design, development and therapy
Ma L,Wu F,Shao Q,Chen G,Xu L,Lu F
Mon Jan 10 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells.
Journal of pharmacological sciences
Tong J,Fang J,Zhu T,Xiang P,Shang J,Chen L,Zhao J,Wang Y,Tong L,Sun M
Wed Dec 01 00:00:00 EST 2021
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
British journal of pharmacology
Guo L,Zhang T,Wang F,Chen X,Xu H,Zhou C,Chen M,Yu F,Wang S,Yang D,Wu B
Fri Jan 01 00:00:00 EST 2021
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Experimental and therapeutic medicine
Zhang Z,Qin X,Wang Z,Li Y,Chen F,Chen R,Li C,Zhang W,Zhang M
Tue Jun 01 00:00:00 EDT 2021
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Ecotoxicology and environmental safety
Zhao G,Qi L,Wang Y,Li X,Li Q,Tang X,Wang X,Wu C
Fri Oct 01 00:00:00 EDT 2021
Polydatin mitigates pancreatic β-cell damage through its antioxidant activity.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yousef AI,Shawki HH,El-Shahawy AA,El-Twab SMA,Abdel-Moneim A,Oishi H
Fri Jan 01 00:00:00 EST 2021
Adenosine 5'-monophosphate-activated protein kinase ameliorates bovine adipocyte oxidative stress by inducing antioxidant responses and autophagy.
Journal of dairy science
Xu Q,Fan Y,Loor JJ,Liang Y,Sun X,Jia H,Zhao C,Xu C
Thu Apr 01 00:00:00 EDT 2021
S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs.
Toxicology and applied pharmacology
Wang Y,Wang HL,Xing GD,Qian Y,Zhong JF,Chen KL
Thu Apr 01 00:00:00 EDT 2021
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Chemical research in toxicology
Kato R,Ijiri Y,Hayashi T
Mon Aug 16 00:00:00 EDT 2021
Up-regulation of heme oxygenase-1 by celastrol alleviates oxidative stress and vascular calcification in chronic kidney disease.
Free radical biology & medicine
Yang X,Chen A,Liang Q,Dong Q,Fu M,Liu X,Wang S,Li Y,Ye Y,Lan Z,Ou JS,Lu L,Yan J
Fri Aug 20 00:00:00 EDT 2021
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Free radical biology & medicine
Tocmo R,Le B,Heun A,van Pijkeren JP,Parkin K,Johnson JJ
Mon Feb 01 00:00:00 EST 2021
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Frontiers in cardiovascular medicine
Wu X,Zhang T,Lyu P,Chen M,Ni G,Cheng H,Xu G,Li X,Wang L,Shang H
Tue Aug 03 00:00:00 EDT 2021
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Cell death discovery
Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z
Tue Mar 23 00:00:00 EDT 2021
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Brain research bulletin
Hou X,Liu H,Ping Y,Zhang F,Zhi L,Jiang X,Zhang F,Song C,Zhang Z,Song J
Sun Aug 01 00:00:00 EDT 2021
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway.
Redox biology
Shi J,Yu T,Song K,Du S,He S,Hu X,Li X,Li H,Dong S,Zhang Y,Xie Z,Li C,Yu J
Sat May 01 00:00:00 EDT 2021
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
American journal of translational research
Tu Z,Jiang X,Li Y,Yang S,Lin D,Shi Y,Mao C,Zhang X,Lin C
Tue Apr 13 00:00:00 EDT 2021
Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment.
Journal of cellular physiology
Li J,Chen H,Lou J,Bao G,Wu C,Lou Z,Wang X,Ding J,Li Z,Xiao J,Xu H,Gao W,Zhou K
Sat May 01 00:00:00 EDT 2021
4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response.
Frontiers in pharmacology
Li R,Yang W,Yin Y,Ma X,Zhang P,Tao K
Sat Jun 12 00:00:00 EDT 2021
Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase 1 Signaling Pathway in vitro Studies.
International journal of nanomedicine
Zou L,Cheng G,Xu C,Liu H,Wang Y,Li N,Fan X,Zhu C,Xia W
Fri Mar 26 00:00:00 EDT 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 EDT 2021
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan S,Liu X,Wang Y,Ren X,Liu Y,Dong Y,Fan Q,Wei J,Ma J,Yu A,Song R,Sui H,Shen M,Fang F,Xia Q,She G
Fri Oct 01 00:00:00 EDT 2021
Notoginsenoside R1 Protects Against High Glucose-Induced Cell Injury Through AMPK/Nrf2 and Downstream HO-1 Signaling.
Frontiers in cell and developmental biology
Du F,Huang H,Cao Y,Ran Y,Wu Q,Chen B
Tue Dec 21 00:00:00 EST 2021
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Journal of agricultural and food chemistry
Zhang Q,Su G,Yang Q,Wei Z,Wang J,Zheng L,Zhao M
Wed Sep 15 00:00:00 EDT 2021
An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury.
Science advances
Mu X,Wang J,He H,Li Q,Yang B,Wang J,Liu H,Gao Y,Ouyang L,Sun S,Ren Q,Shi X,Hao W,Fei Q,Yang J,Li L,Vest R,Wyss-Coray T,Luo J,Zhang XD
Fri Nov 12 00:00:00 EST 2021
An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury.
Science advances
Mu X,Wang J,He H,Li Q,Yang B,Wang J,Liu H,Gao Y,Ouyang L,Sun S,Ren Q,Shi X,Hao W,Fei Q,Yang J,Li L,Vest R,Wyss-Coray T,Luo J,Zhang XD
Fri Nov 12 00:00:00 EST 2021
Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction.
European journal of medicinal chemistry
Zhou W,Xu C,Dong G,Qiao H,Yang J,Liu H,Ding L,Sun K,Zhao W
Wed May 05 00:00:00 EDT 2021
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Frontiers in pharmacology
Zhang X,Zhang Y,Zhou M,Xie Y,Dong X,Bai F,Zhang J
Fri Feb 04 00:00:00 EST 2022
Acupuncture Ameliorates Neuronal Cell Death, Inflammation, and Ferroptosis and Downregulated miR-23a-3p After Intracerebral Hemorrhage in Rats.
Journal of molecular neuroscience : MN
Kong Y,Li S,Zhang M,Xu W,Chen Q,Zheng L,Liu P,Zou W
Wed Sep 01 00:00:00 EDT 2021
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Journal of orthopaedic translation
Yao X,Sun K,Yu S,Luo J,Guo J,Lin J,Wang G,Guo Z,Ye Y,Guo F
Mon Mar 01 00:00:00 EST 2021
GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhu L,Chen D,Zhu Y,Pan T,Xia D,Cai T,Lin H,Lin J,Jin X,Wu F,Yu S,Zhu K,Xu L,Chen Y
Thu Mar 03 00:00:00 EST 2022
The novel nanocomplexes containing deoxycholic acid-grafted chitosan and oleanolic acid displays the hepatoprotective effect against CCl4-induced liver injury in vivo.
International journal of biological macromolecules
Xin C,Liu S,Qu H,Wang Z
Tue Aug 31 00:00:00 EDT 2021
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Immunity, inflammation and disease
Chen G,Yang Z,Wen D,Guo J,Xiong Q,Li P,Zhao L,Wang J,Wu C,Dong L
Wed Sep 01 00:00:00 EDT 2021
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Medical science monitor : international medical journal of experimental and clinical research
Pan H,Xu Y,Cai Q,Wu M,Ding M
Fri Jun 04 00:00:00 EDT 2021
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
International immunopharmacology
Wen L,Yang QH,Ma XL,Li T,Xiao S,Sun CF
Fri Oct 01 00:00:00 EDT 2021
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
The British journal of nutrition
Zhang M,Hou G,Hu P,Feng D,Wang J,Zhu W
Tue Sep 28 00:00:00 EDT 2021
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T
Fri Jan 01 00:00:00 EST 2021
Protective effect of cynaroside on sepsis-induced multiple organ injury through Nrf2/HO-1-dependent macrophage polarization.
European journal of pharmacology
Feng J,Liu Z,Chen H,Zhang M,Ma X,Han Q,Lu D,Wang C
Mon Nov 15 00:00:00 EST 2021
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats.
Journal of drug targeting
Peng J,Jiang Z,Wu G,Cai Z,Du Q,Tao L,Zhang Y,Chen Y,Shen X
Tue Jun 01 00:00:00 EDT 2021
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats.
Journal of drug targeting
Peng J,Jiang Z,Wu G,Cai Z,Du Q,Tao L,Zhang Y,Chen Y,Shen X
Tue Jun 01 00:00:00 EDT 2021
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Cell death & disease
Kong L,Deng J,Zhou X,Cai B,Zhang B,Chen X,Chen Z,Wang W
Mon Oct 11 00:00:00 EDT 2021
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Frontiers in pharmacology
Zhou F,Zhang X,Jiang L,Li S,Chen Y,Wu J
Tue May 18 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
Polyphenols from Penthorum chinense Pursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein.
Journal of ethnopharmacology
Sun Y,He L,Wang W,Wang T,Hua W,Li T,Wang L,Gao T,Chen F,Tang L
Thu Mar 25 00:00:00 EDT 2021
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Journal of neuroimmunology
Xu X,Xu H,Ren F,Huang L,Xu J,Li F
Tue Jun 15 00:00:00 EDT 2021
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Oxidative medicine and cellular longevity
Zhu X,Hu X,Lou J,Li J,Xu Y,Yu G,Wu C,Ding J,Gao W,Xiao J,Zhou K,Jia C
Fri May 28 00:00:00 EDT 2021
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Cell proliferation
Xu Y,Sang W,Zhong Y,Xue S,Yang M,Wang C,Lu H,Huan R,Mao X,Zhu L,He C,Ma J
Wed Dec 01 00:00:00 EST 2021
Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway.
Journal of immunology research
Lin Y,Xie Y,Hao Z,Bi H,Liu Y,Yang X,Xia Y
Thu Mar 03 00:00:00 EST 2022
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Clinical science (London, England : 1979)
Wu M,Chen W,Miao M,Jin Q,Zhang S,Bai M,Fan J,Zhang Y,Zhang A,Jia Z,Huang S
Fri Jul 30 00:00:00 EDT 2021
Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Bao S,Zheng H,Chen C,Zhang Y,Bao L,Yang B,Hou Y,Chen Y,Zhang Q,Pi J,Fu J
Wed Dec 01 00:00:00 EST 2021
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.
Oxidative medicine and cellular longevity
Chen H,Chen B,Li B,Luo X,Wu H,Zhang C,Liu J,Jiang J,Zhao B
Tue Sep 14 00:00:00 EDT 2021
Baicalin-loaded macrophage-derived exosomes ameliorate ischemic brain injury via the antioxidative pathway.
Materials science & engineering. C, Materials for biological applications
Huang Z,Guo L,Huang L,Shi Y,Liang J,Zhao L
Thu Jul 01 00:00:00 EDT 2021
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
European journal of pharmacology
Chen Y,Wang J,Li J,Zhu J,Wang R,Xi Q,Wu H,Shi T,Chen W
Mon Nov 15 00:00:00 EST 2021
Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu P,Li J,Liu M,Zhang M,Xue Y,Zhang Y,Han X,Jing X,Chu L
Thu Jul 01 00:00:00 EDT 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 EDT 2021
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Journal of ethnopharmacology
Zhou F,Song Y,Liu X,Zhang C,Li F,Hu R,Huang Y,Ma W,Song K,Zhang M
Mon Nov 15 00:00:00 EST 2021
The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang M,Ke Y,Li Y,Shan Z,Mi W,Cao Y,Feng W,Zheng X
Tue Jun 01 00:00:00 EDT 2021
Buyang Huanwu Decoction Enhances Revascularization via Akt/GSK3β/NRF2 Pathway in Diabetic Hindlimb Ischemia.
Oxidative medicine and cellular longevity
Bao XY,Deng LH,Huang ZJ,Daror AS,Wang ZH,Jin WJ,Zhuang Z,Tong Q,Zheng GQ,Wang Y
Tue Feb 22 00:00:00 EST 2022
CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.
Pharmacological research
Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H
Fri Jan 01 00:00:00 EST 2021
Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo.
Chinese medicine
Liu Y,Zhou J,Luo Y,Li J,Shang L,Zhou F,Yang S
Mon Nov 29 00:00:00 EST 2021
DCA Protects against Oxidation Injury Attributed to Cerebral Ischemia-Reperfusion by Regulating Glycolysis through PDK2-PDH-Nrf2 Axis.
Oxidative medicine and cellular longevity
Zhao X,Li S,Mo Y,Li R,Huang S,Zhang A,Ni X,Dai Q,Wang J
Mon Feb 07 00:00:00 EST 2022
DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress.
Acta pharmacologica Sinica
Wang BN,Wu CB,Chen ZM,Zheng PP,Liu YQ,Xiong J,Xu JY,Li PF,Mamun AA,Ye LB,Zheng ZL,Wu YQ,Xiao J,Wang J
Mon Mar 01 00:00:00 EST 2021
Proteome Analysis of Camellia nitidissima Chi Revealed Its Role in Colon Cancer Through the Apoptosis and Ferroptosis Pathway.
Frontiers in oncology
Chen Y,Zhang F,Du Z,Xie J,Xia L,Hou X,Hao E,Deng J
Sat Dec 04 00:00:00 EST 2021
Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury.
Antioxidants (Basel, Switzerland)
Dai C,Li H,Wang Y,Tang S,Velkov T,Shen J
Fri Jun 18 00:00:00 EDT 2021
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
Oxidative medicine and cellular longevity
Wang H,Zhao K,Ba Y,Gao T,Shi N,Niu Q,Liu C,Chen Y
Thu May 20 00:00:00 EDT 2021
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
Oxidative medicine and cellular longevity
Wang H,Zhao K,Ba Y,Gao T,Shi N,Niu Q,Liu C,Chen Y
Thu May 20 00:00:00 EDT 2021
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance.
Nature communications
Cui M,Atmanli A,Morales MG,Tan W,Chen K,Xiao X,Xu L,Liu N,Bassel-Duby R,Olson EN
Mon Sep 06 00:00:00 EDT 2021
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Experimental cell research
Xi X,Zhao Y,Liu H,Li Z,Chen S,Liu D
Tue Jun 15 00:00:00 EDT 2021
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Weng WT,Kuo PC,Brown DA,Scofield BA,Furnas D,Paraiso HC,Wang PY,Yu IC,Yen JH
Tue May 11 00:00:00 EDT 2021
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Aging
Yang RZ,Zheng HL,Xu WN,Zheng XF,Li B,Jiang LS,Jiang SD
Mon Feb 01 00:00:00 EST 2021
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Nature
Wang Y,Yen FS,Zhu XG,Timson RC,Weber R,Xing C,Liu Y,Allwein B,Luo H,Yeh HW,Heissel S,Unlu G,Gamazon ER,Kharas MG,Hite R,Birsoy K
Mon Nov 01 00:00:00 EDT 2021
The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis.
Bioorganic chemistry
Jin J,He H,Zhang X,Wu R,Gan L,Li D,Lu Y,Wu P,Wong WL,Zhang K
Sun Aug 01 00:00:00 EDT 2021
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Technology and health care : official journal of the European Society for Engineering and Medicine
Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J
Wed Aug 18 00:00:00 EDT 2021
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Environmental toxicology
Ren F,Xu X,Xu J,Mei Y,Zhang J,Wang X,Li F
Wed Sep 01 00:00:00 EDT 2021
The role of transcription factor Ap1 in the activation of the Nrf2/ARE pathway through TET1 in diabetic nephropathy.
Cell biology international
Tan Y,Cao H,Li Q,Sun J
Sun Aug 01 00:00:00 EDT 2021
Bilirubin Oxidation End Products (BOXes) Induce Neuronal Oxidative Stress Involving the Nrf2 Pathway.
Oxidative medicine and cellular longevity
Lu Y,Zhang W,Zhang B,Heinemann SH,Hoshi T,Hou S,Zhang G
Thu Jan 06 00:00:00 EST 2022
Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway.
Ecotoxicology and environmental safety
Cao L,Zhao J,Ma L,Chen J,Xu J,Rahman SU,Feng S,Li Y,Wu J,Wang X
Wed Dec 01 00:00:00 EST 2021
Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation.
eLife
Lei I,Tian S,Gao W,Liu L,Guo Y,Tang P,Chen E,Wang Z
Thu Dec 23 00:00:00 EST 2021
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Toxicology
Liu Z,He Q,Liu Y,Zhang Y,Cui M,Peng H,Wang Y,Chen S,Li D,Chen L,Xiao Y,Chen W,Wang Q
Wed Jun 30 00:00:00 EDT 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 EST 2021
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Biochemical and biophysical research communications
Li X,Wang X,Miao L,Guo Y,Yuan R,Tian H
Fri Jun 04 00:00:00 EDT 2021
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Free radical biology & medicine
Hong J,Shi Z,Li C,Ji X,Li S,Chen Y,Jiang G,Shi M,Wang W,Zhang Y,Hu B,Yan S
Sun Aug 01 00:00:00 EDT 2021
Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis.
Free radical biology & medicine
Hong J,Shi Z,Li C,Ji X,Li S,Chen Y,Jiang G,Shi M,Wang W,Zhang Y,Hu B,Yan S
Sun Aug 01 00:00:00 EDT 2021
Proteomics analysis in the kidney of mice following oral feeding Realgar.
Journal of ethnopharmacology
Zhang S,Li C,Feng T,Cao S,Zhou H,Li L,Hu Q,Mao X,Ji S
Thu Jul 15 00:00:00 EDT 2021
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Brain research bulletin
Peng W,Zhu Z,Yang Y,Hou J,Lu J,Chen C,Liu F,Pi R
Wed Sep 01 00:00:00 EDT 2021
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells.
Brain research bulletin
Peng W,Zhu Z,Yang Y,Hou J,Lu J,Chen C,Liu F,Pi R
Wed Sep 01 00:00:00 EDT 2021
Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhao SJ,Liu H,Chen J,Qian DF,Kong FQ,Jie J,Yin GY,Li QQ,Fan J
Thu Oct 01 00:00:00 EDT 2020
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Cell death & disease
Liu H,Zhu Y,Gao Y,Qi D,Zhao L,Zhao L,Liu C,Tao T,Zhou C,Sun X,Guo F,Xiao J
Tue Feb 18 00:00:00 EST 2020
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Brain research
Li Y,Wu J,Yu S,Zhu J,Zhou Y,Wang P,Li L,Zhao Y
Thu Oct 15 00:00:00 EDT 2020
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Cell proliferation
Tang Q,Ren L,Liu J,Li W,Zheng X,Wang J,Du G
Wed Jan 01 00:00:00 EST 2020
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Cell proliferation
Tang Q,Ren L,Liu J,Li W,Zheng X,Wang J,Du G
Wed Jan 01 00:00:00 EST 2020
Bach1-induced suppression of angiogenesis is dependent on the BTB domain.
EBioMedicine
Jiang L,Jia M,Wei X,Guo J,Hao S,Mei A,Zhi X,Wang X,Li Q,Jin J,Zhang J,Li S,Meng D
Wed Jan 01 00:00:00 EST 2020
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress.
Theranostics
Zhou K,Zheng Z,Li Y,Han W,Zhang J,Mao Y,Chen H,Zhang W,Liu M,Xie L,Zhang H,Xu H,Xiao J
Fri May 28 00:00:00 EDT 2021
A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4-dependent NLRP3 inflammasome activation.
Journal of cellular and molecular medicine
Pan LL,Ren Z,Liu Y,Zhao Y,Li H,Pan X,Fang X,Liang W,Wang Y,Yang J,Sun J
Sun Nov 01 00:00:00 EDT 2020
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Drug design, development and therapy
Gao Z,Sui J,Fan R,Qu W,Dong X,Sun D
Mon Mar 29 00:00:00 EDT 2021
Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques.
Oxidative medicine and cellular longevity
Zavaczki E,Gáll T,Zarjou A,Hendrik Z,Potor L,Tóth CZ,Méhes G,Gyetvai Á,Agarwal A,Balla G,Balla J
Tue Nov 10 00:00:00 EST 2020
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhou D,Yang Q,Tian T,Chang Y,Li Y,Duan LR,Li H,Wang SW
Mon Jun 01 00:00:00 EDT 2020
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM2.5 from Beijing, China, in Winter.
International journal of environmental research and public health
Niu BY,Li WK,Li JS,Hong QH,Khodahemmati S,Gao JF,Zhou ZX
Mon Jul 06 00:00:00 EDT 2020
Protective Effects of Crocetin on Arsenic Trioxide-Induced Hepatic Injury: Involvement of Suppression in Oxidative Stress and Inflammation Through Activation of Nrf2 Signaling Pathway in Rats.
Drug design, development and therapy
Liu Y,Liang Y,Zheng B,Chu L,Ma D,Wang H,Chu X,Zhang J
Mon Mar 29 00:00:00 EDT 2021
Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats.
Oncology reports
Li M,Liu P,Xue Y,Liang Y,Shi J,Han X,Zhang J,Chu X,Chu L
Sun Nov 01 00:00:00 EDT 2020
Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System.
Antioxidants (Basel, Switzerland)
Tanaka Y,Ito T,Tsuji G,Furue M
Tue Jun 09 00:00:00 EDT 2020
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Frontiers in pharmacology
Hu J,Zhu Z,Ying H,Yao J,Ma H,Li L,Zhao Y
Sat Feb 06 00:00:00 EST 2021
Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Chen S,Qin L,Wu X,Fu X,Lin S,Chen D,Xiao G,Shao Z,Cao H
Mon Sep 28 00:00:00 EDT 2020
Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Chen S,Qin L,Wu X,Fu X,Lin S,Chen D,Xiao G,Shao Z,Cao H
Mon Sep 28 00:00:00 EDT 2020
Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.
Life sciences
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sat Feb 15 00:00:00 EST 2020
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Free radical biology & medicine
Zhang P,Yin Y,Wang T,Li W,Li C,Zeng X,Yang W,Zhang R,Tang Y,Shi L,Li R,Tao K
Sat Feb 01 00:00:00 EST 2020
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Frontiers in pharmacology
Li B,Chen Z,Luo X,Zhang C,Chen H,Wang S,Zhao M,Ma H,Liu J,Cheng M,Yang Y,Yan H
Tue Feb 16 00:00:00 EST 2021
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Toxicology and applied pharmacology
Ma Z,Lu Y,Yang F,Li S,He X,Gao Y,Zhang G,Ren E,Wang Y,Kang X
Sun Apr 19 00:00:00 EDT 2020
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Frontiers in pharmacology
Deng HF,Yue LX,Wang NN,Zhou YQ,Zhou W,Liu X,Ni YH,Huang CS,Qiu LZ,Liu H,Tan HL,Tang XL,Wang YG,Ma ZC,Gao Y
Tue Feb 16 00:00:00 EST 2021
Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system.
Cell death discovery
Jiao Z,Wu Y,Qu S
Tue Sep 26 00:00:00 EDT 2023
Effects of grape seed proanthocyanidin B2 pretreatment on oxidative stress and renal tubular epithelial cell apoptosis after renal ischemia reperfusion in mice.
Acta cirurgica brasileira
Wang ZS,Zhou HH,Han Q,Guo YL,Li ZY
Fri Sep 04 00:00:00 EDT 2020
Effects of grape seed proanthocyanidin B2 pretreatment on oxidative stress and renal tubular epithelial cell apoptosis after renal ischemia reperfusion in mice.
Acta cirurgica brasileira
Wang ZS,Zhou HH,Han Q,Guo YL,Li ZY
Fri Sep 04 00:00:00 EDT 2020
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Qi D,Liu H,Sun X,Luo D,Zhu M,Tao T,Gao C,Zhou C,Zhou W,Xiao J
Fri Feb 26 00:00:00 EST 2021
Discovery of a novel ferroptosis inducer-talaroconvolutin A-killing colorectal cancer cells in vitro and in vivo.
Cell death & disease
Xia Y,Liu S,Li C,Ai Z,Shen W,Ren W,Yang X
Tue Nov 17 00:00:00 EST 2020
USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells.
Experimental cell research
Huang K,Zhao X
Sat Aug 15 00:00:00 EDT 2020
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Kuo PC,Weng WT,Scofield BA,Paraiso HC,Brown DA,Wang PY,Yu IC,Yen JH
Wed Apr 29 00:00:00 EDT 2020
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Kuo PC,Weng WT,Scofield BA,Paraiso HC,Brown DA,Wang PY,Yu IC,Yen JH
Wed Apr 29 00:00:00 EDT 2020
Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells.
Antioxidants (Basel, Switzerland)
Jasek-Gajda E,Jurkowska H,Jasińska M,Lis GJ
Fri Jul 17 00:00:00 EDT 2020
Effects of Compound Centella on Oxidative Stress and Keap1-Nrf2-ARE Pathway Expression in Diabetic Kidney Disease Rats.
Evidence-based complementary and alternative medicine : eCAM
Zhu Q,Zeng J,Li J,Chen X,Miao J,Jin Q,Chen H
Mon Sep 28 00:00:00 EDT 2020
Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy.
Cell death & disease
Xu Q,Shi W,Lv P,Meng W,Mao G,Gong C,Chen Y,Wei Y,He X,Zhao J,Han H,Sun M,Xiao K
Thu Jan 02 00:00:00 EST 2020
Cucurbitacin I induces apoptosis in ovarian cancer cells through oxidative stress and the p190B‑Rac1 signaling axis.
Molecular medicine reports
Li R,Xiao J,Tang S,Lin X,Xu H,Han B,Yang M,Liu F
Tue Sep 01 00:00:00 EDT 2020
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Oxidative medicine and cellular longevity
Qi J,Chen X,Wu Q,Wang J,Zhang H,Mao A,Zhu M,Miao C
Tue Nov 17 00:00:00 EST 2020
Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy.
Frontiers in cellular neuroscience
Li Y,Xiang J,Zhang J,Lin J,Wu Y,Wang X
Thu Oct 01 00:00:00 EDT 2020
Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Yao H,Sun J,Wei J,Zhang X,Chen B,Lin Y
Mon Sep 28 00:00:00 EDT 2020
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
European journal of pharmacology
Wang J,Zhang X,Zhang L,Yan T,Wu B,Xu F,Jia Y
Sat Aug 15 00:00:00 EDT 2020
Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression.
Environment international
Liu J,Tan Y,Yang B,Wu Y,Fan B,Zhu S,Song E,Song Y
Mon Jun 01 00:00:00 EDT 2020
Silibinin ameliorats H2O2-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells.
Acta histochemica
Guo H,Wang Y,Liu D
Tue Dec 01 00:00:00 EST 2020
PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway.
Stem cell research & therapy
Yao X,Yu S,Jing X,Guo J,Sun K,Guo F,Ye Y
Mon Mar 30 00:00:00 EDT 2020
Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival.
Frontiers in pharmacology
Chen Z,Zhang C,Ma H,Huang Z,Li J,Lou J,Li B,Tu Q,Gao W
Mon Sep 28 00:00:00 EDT 2020
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
Laboratory investigation; a journal of technical methods and pathology
Kong H,Wang H,Zhuo Z,Li Z,Tian P,Wu J,Liu J,Chen Z,Zhang J,Luo Q
Tue Sep 01 00:00:00 EDT 2020
Brainstem iron overload and injury in a rat model of brainstem hemorrhage.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Guo X,Ma L,Li H,Qi X,Wei Y,Duan Z,Xu J,Wang C,You C,Tian M
Sat Aug 01 00:00:00 EDT 2020
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pharmaceutical biology
Zhang X,Feng J,Su S,Huang L
Tue Dec 01 00:00:00 EST 2020
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Wang Y,Li C,Li J,Wang G,Li L
Sun Jun 14 00:00:00 EDT 2020
Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway.
Biomolecules & therapeutics
Zhang X,Wang J,Gong G,Ma R,Xu F,Yan T,Wu B,Jia Y
Fri May 01 00:00:00 EDT 2020
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment.
Aging
Chen X,Amorim JA,Moustafa GA,Lee JJ,Yu Z,Ishihara K,Iesato Y,Barbisan P,Ueta T,Togka KA,Lu L,Sinclair DA,Vavvas DG
Tue Dec 29 00:00:00 EST 2020
Metformin attenuates cardiac remodeling in mice through the Nrf2/Keap1 signaling pathway.
Experimental and therapeutic medicine
Du J,Zhu M,Li H,Liang G,Li Y,Feng S
Sat Aug 01 00:00:00 EDT 2020
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Autophagy
Yang B,Xue Q,Guo J,Wang X,Zhang Y,Guo K,Li W,Chen S,Xue T,Qi X,Wang J
Fri May 01 00:00:00 EDT 2020
Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zhou L,Ao L,Yan Y,Li C,Li W,Ye A,Liu J,Hu Y,Fang W,Li Y
Wed Jan 01 00:00:00 EST 2020
Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zhou L,Ao L,Yan Y,Li C,Li W,Ye A,Liu J,Hu Y,Fang W,Li Y
Wed Jan 01 00:00:00 EST 2020
Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zhou L,Ao L,Yan Y,Li C,Li W,Ye A,Liu J,Hu Y,Fang W,Li Y
Wed Jan 01 00:00:00 EST 2020
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Journal of medicinal food
Li H,Liang M,Wang Z,Zhang Y,Wu Q,Yang L
Mon Jun 01 00:00:00 EDT 2020
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
Frontiers in immunology
Chen S,Ding R,Hu Z,Yin X,Xiao F,Zhang W,Yan S,Lv C
Mon Apr 12 00:00:00 EDT 2021
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
Stem cell research & therapy
Yin N,Wu C,Qiu J,Zhang Y,Bo L,Xu Y,Shi M,Zhu S,Yang G,Mao C
Tue Feb 04 00:00:00 EST 2020
Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats.
International immunopharmacology
Fang D,Lin Q,Wang C,Zheng C,Li Y,Huang T,Ni F,Wu Z,Chen B,Sun L
Sun Mar 01 00:00:00 EST 2020
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Cell death & disease
Zhang Y,Zhao S,Fu Y,Yan L,Feng Y,Chen Y,Wu Y,Deng Y,Zhang G,Chen Z,Chen Y,Liu T
Tue Aug 18 00:00:00 EDT 2020
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Frontiers in pharmacology
Xu Q,Fan Y,Loor JJ,Liang Y,Sun X,Jia H,Zhao C,Xu C
Thu Dec 31 00:00:00 EST 2020
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Antioxidants (Basel, Switzerland)
Sun B,Wang X,Liu X,Wang L,Ren F,Wang X,Leng X
Tue Aug 25 00:00:00 EDT 2020
The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.
Cell proliferation
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sun Mar 01 00:00:00 EST 2020
4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways.
American journal of translational research
Wei X,Wang H,Sun X,Huang X,Xu W,Liang Y,Liu L,Mo S,Lin X,Lin J
Mon Sep 28 00:00:00 EDT 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 EDT 2020
Syringin protects against colitis by ameliorating inflammation.
Archives of biochemistry and biophysics
Zhang H,Gu H,Jia Q,Zhao Y,Li H,Shen S,Liu X,Wang G,Shi Q
Sat Feb 15 00:00:00 EST 2020
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhu M,Liu H,Sun K,Liu J,Mou Y,Qi D,Zhou C,Abudunaibi M,Tasiken B,Li J,Cheng H,Huang H
Sun Mar 01 00:00:00 EST 2020
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Acta biochimica et biophysica Sinica
Chen X,Qi J,Wu Q,Jiang H,Wang J,Chen W,Mao A,Zhu M
Tue May 26 00:00:00 EDT 2020
Hesperidin ameliorates hypobaric hypoxia-induced retinal impairment through activation of Nrf2/HO-1 pathway and inhibition of apoptosis.
Scientific reports
Xin X,Li Y,Liu H
Tue Nov 10 00:00:00 EST 2020
Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Zhao M,Tang X,Gong D,Xia P,Wang F,Xu S
Mon Sep 28 00:00:00 EDT 2020
Heme oxygenase-1-modified bone marrow mesenchymal stem cells combined with normothermic machine perfusion to protect donation after circulatory death liver grafts.
Stem cell research & therapy
Cao H,Yang L,Hou B,Sun D,Lin L,Song HL,Shen ZY
Fri Jun 05 00:00:00 EDT 2020
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-B Pathway.
The American journal of Chinese medicine
Wu J,Yang CL,Sha YK,Wu Y,Liu ZY,Yuan ZH,Sun ZL
Fri Sep 04 00:00:00 EDT 2020
Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice.
BioMed research international
Du J,He W,Zhang C,Wu J,Li Z,Wang M,Feng S,Liang G
Mon Nov 23 00:00:00 EST 2020
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Drug design, development and therapy
Kong J,Wang J,Gong X,Zheng X,Chen T
Tue Sep 21 00:00:00 EDT 2021
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Journal of food biochemistry
Wang Z,Cai L,Li H,Liang M,Zhang Y,Wu Q,Yang L
Fri May 01 00:00:00 EDT 2020
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine.
Antioxidants (Basel, Switzerland)
Liou SF,Nguyen TTN,Hsu JH,Sulistyowati E,Huang SE,Wu BN,Lin MC,Yeh JL
Tue Oct 06 00:00:00 EDT 2020
H-Ferritin is essential for macrophages' capacity to store or detoxify exogenously added iron.
Scientific reports
Mesquita G,Silva T,Gomes AC,Oliveira PF,Alves MG,Fernandes R,Almeida AA,Moreira AC,Gomes MS
Thu Feb 20 00:00:00 EST 2020
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Food & function
Gu M,Jin J,Ren C,Chen X,Gao W,Wang X,Wu Y,Tian N,Pan Z,Wu A,Zhou Y,Zhang X
Tue Dec 01 00:00:00 EST 2020
Antioxidant activity of selenium-enriched Chrysomyia megacephala (Fabricius) larvae powder and its impact on intestinal microflora in D-galactose induced aging mice.
BMC complementary medicine and therapies
Xie D,Jiang L,Lin Y,Liu Z
Thu Aug 27 00:00:00 EDT 2020
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Science translational medicine
Jiang TY,Pan YF,Wan ZH,Lin YK,Zhu B,Yuan ZG,Ma YH,Shi YY,Zeng TM,Dong LW,Tan YX,Wang HY
Wed Sep 23 00:00:00 EDT 2020
Fibroblast growth factor 19 alleviates palmitic acid-induced mitochondrial dysfunction and oxidative stress via the AMPK/PGC-1α pathway in skeletal muscle.
Biochemical and biophysical research communications
Guo A,Li K,Xiao Q
Thu Jun 11 00:00:00 EDT 2020
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Oxidative medicine and cellular longevity
Li X,Zou Y,Xing J,Fu YY,Wang KY,Wan PZ,Zhai XY
Mon Sep 21 00:00:00 EDT 2020
Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway.
Oxidative medicine and cellular longevity
Li X,Zou Y,Xing J,Fu YY,Wang KY,Wan PZ,Zhai XY
Mon Sep 21 00:00:00 EDT 2020
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Neural regeneration research
Xiong Y,Xin DQ,Hu Q,Wang LX,Qiu J,Yuan HT,Chu XL,Liu DX,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.
Oxidative medicine and cellular longevity
Meng X,Zhang C,Guo Y,Han Y,Wang C,Chu H,Kong L,Ma H
Thu Feb 04 00:00:00 EST 2021
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Oxidative medicine and cellular longevity
Chen S,Liu S,Zhao L,Lin H,Ma K,Shao Z
Tue Nov 10 00:00:00 EST 2020
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Molecules (Basel, Switzerland)
Dong Y,Xing Y,Sun J,Sun W,Xu Y,Quan C
Thu Jan 30 00:00:00 EST 2020
Icariin Prevents Extracellular Matrix Accumulation and Ameliorates Experimental Diabetic Kidney Disease by Inhibiting Oxidative Stress via GPER Mediated p62-Dependent Keap1 Degradation and Nrf2 Activation.
Frontiers in cell and developmental biology
Wang K,Zheng X,Pan Z,Yao W,Gao X,Wang X,Ding X
Mon Sep 28 00:00:00 EDT 2020
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Evidence-based complementary and alternative medicine : eCAM
Tian TT,Li QR,Gan SQ,Chang CR,Shen XC
Mon Sep 28 00:00:00 EDT 2020
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway.
Environmental pollution (Barking, Essex : 1987)
Liu J,Yang B,Wang Y,Wu Y,Fan B,Zhu S,Song E,Song Y
Sat Feb 01 00:00:00 EST 2020
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Wang J,Fang Z,Song C,Kang H,Guo Q,Dong Y,Zhang Y,Peng R,Guan H,Li F
Mon Sep 28 00:00:00 EDT 2020
7-methoxyflavanone alleviates neuroinflammation in lipopolysaccharide-stimulated microglial cells by inhibiting TLR4/MyD88/MAPK signalling and activating the Nrf2/NQO-1 pathway.
The Journal of pharmacy and pharmacology
Qu Z,Chen Y,Luo ZH,Shen XL,Hu YJ
Sun Mar 01 00:00:00 EST 2020
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Food & function
Lin Z,Fu C,Yan Z,Wu Y,Zhan J,Lou Z,Liao X,Pan J
Thu Mar 26 00:00:00 EDT 2020
Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway.
Antioxidants (Basel, Switzerland)
Nishikawa S,Inoue Y,Hori Y,Miyajima C,Morishita D,Ohoka N,Hida S,Makino T,Hayashi H
Wed Sep 09 00:00:00 EDT 2020
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Life sciences
Shopit A,Niu M,Wang H,Tang Z,Li X,Tesfaldet T,Ai J,Ahmad N,Al-Azab M,Tang Z
Sat Feb 01 00:00:00 EST 2020
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Virulence
You L,Chen J,Liu W,Xiang Q,Luo Z,Wang W,Xu W,Wu K,Zhang Q,Liu Y,Wu J
Tue Dec 01 00:00:00 EST 2020
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
The Journal of toxicological sciences
Kato R,Ijiri Y,Hayashi T,Uetrecht J
Mon Nov 23 00:00:00 EST 2020
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 EDT 2019
Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway.
Journal of cellular physiology
Zhong L,Hao H,Chen D,Hou Q,Zhu Z,He W,Sun S,Sun M,Li M,Fu X
Fri Mar 01 00:00:00 EST 2019
Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway.
Journal of cellular physiology
Zhong L,Hao H,Chen D,Hou Q,Zhu Z,He W,Sun S,Sun M,Li M,Fu X
Fri Mar 01 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 EST 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 EST 2019
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Metabolic brain disease
Gao W,Wang W,Liu G,Zhang J,Yang J,Deng Z
Fri Feb 01 00:00:00 EST 2019
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Metabolic brain disease
Gao W,Wang W,Liu G,Zhang J,Yang J,Deng Z
Fri Feb 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Journal of molecular neuroscience : MN
Yang Q,Lin J,Zhang H,Liu Y,Kan M,Xiu Z,Chen X,Lan X,Li X,Shi X,Li N,Qu X
Tue Jan 01 00:00:00 EST 2019
Predictable chronic mild stress promotes recovery from LPS-induced depression.
Molecular brain
Dang R,Guo YY,Zhang K,Jiang P,Zhao MG
Fri May 03 00:00:00 EDT 2019
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Biological & pharmaceutical bulletin
Yang P,Zhou Y,Xia Q,Yao L,Chang X
Wed May 01 00:00:00 EDT 2019
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Oxidative medicine and cellular longevity
Liu P,Li Y,Yang W,Liu D,Ji X,Chi T,Guo Z,Li L,Zou L
Wed Aug 28 00:00:00 EDT 2019
The memory improving effects of round scad (Decapterus maruadsi) hydrolysates on sleep deprivation-induced memory deficits in rats via antioxidant and neurotrophic pathways.
Food & function
Zhang Q,Su G,Zhao T,Wang S,Sun B,Zheng L,Zhao M
Wed Dec 11 00:00:00 EST 2019
Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways.
BioMed research international
Zhao K,Li Y,Wang Z,Han N,Wang Y
Thu Dec 12 00:00:00 EST 2019
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Cell death & disease
Zhou K,Chen H,Lin J,Xu H,Wu H,Bao G,Li J,Deng X,Shui X,Gao W,Ding J,Xiao J,Xu H
Mon Nov 18 00:00:00 EST 2019
Torularhodin Ameliorates Oxidative Activity in Vitro and d-Galactose-Induced Liver Injury via the Nrf2/HO-1 Signaling Pathway in Vivo.
Journal of agricultural and food chemistry
Liu C,Cui Y,Pi F,Guo Y,Cheng Y,Qian H
Wed Sep 11 00:00:00 EDT 2019
Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells.
Oxidative medicine and cellular longevity
Yan X,Fu X,Jia Y,Ma X,Tao J,Yang T,Ma H,Liang X,Liu X,Yang J,Wei J
Fri Dec 13 00:00:00 EST 2019
Polysaccharide from Okra (Abelmoschus esculentus (L.) Moench) Improves Antioxidant Capacity via PI3K/AKT Pathways and Nrf2 Translocation in a Type 2 Diabetes Model.
Molecules (Basel, Switzerland)
Liao Z,Zhang J,Liu B,Yan T,Xu F,Xiao F,Wu B,Bi K,Jia Y
Fri May 17 00:00:00 EDT 2019
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Cells
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Tue Jun 18 00:00:00 EDT 2019
Soy Isoflavones Improve the Spermatogenic Defects in Diet-Induced Obesity Rats through Nrf2/HO-1 Pathway.
Molecules (Basel, Switzerland)
Luo Q,Li Y,Huang C,Cheng D,Ma W,Xia Y,Liu W,Chen Z
Thu Aug 15 00:00:00 EDT 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Journal of experimental & clinical cancer research : CR
Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B
Thu Jan 03 00:00:00 EST 2019
Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice.
Theranostics
Xian P,Hei Y,Wang R,Wang T,Yang J,Li J,Di Z,Liu Z,Baskys A,Liu W,Wu S,Long Q
Mon Aug 31 00:00:00 EDT 2020
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 EDT 2020
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
International journal of molecular medicine
Kang Y,Li Y,Zhang T,Chi Y,Liu M
Thu Aug 01 00:00:00 EDT 2019
Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress.
Drug design, development and therapy
Lin J,Jia C,Wang Y,Jiang S,Jia Z,Chen N,Sheng S,Li S,Jiang L,Xu H,Zhou K,Chen Y
Thu Feb 27 00:00:00 EST 2020
Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis.
Aging
Sun K,Luo J,Jing X,Guo J,Yao X,Hao X,Ye Y,Liang S,Lin J,Wang G,Guo F
Tue Nov 26 00:00:00 EST 2019
Berberine ameliorates CCl4‑induced liver injury in rats through regulation of the Nrf2‑Keap1‑ARE and p53 signaling pathways.
Molecular medicine reports
Han CY,Sun TT,Xv GP,Wang SS,Gu JG,Liu CY
Tue Oct 01 00:00:00 EDT 2019
Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Aβ-Induced Cognitive Impairment in Vivo.
ACS chemical neuroscience
Yan J,Pang Y,Zhuang J,Lin H,Zhang Q,Han L,Ke P,Zhuang J,Huang X
Wed Jun 19 00:00:00 EDT 2019
Deferoxamine Alleviates Iron Overload and Brain Injury in a Rat Model of Brainstem Hemorrhage.
World neurosurgery
Guo X,Qi X,Li H,Duan Z,Wei Y,Zhang F,Tian M,Ma L,You C
Thu Aug 01 00:00:00 EDT 2019
Deferoxamine Alleviates Iron Overload and Brain Injury in a Rat Model of Brainstem Hemorrhage.
World neurosurgery
Guo X,Qi X,Li H,Duan Z,Wei Y,Zhang F,Tian M,Ma L,You C
Thu Aug 01 00:00:00 EDT 2019
Ochratoxin A causes mitochondrial dysfunction, apoptotic and autophagic cell death and also induces mitochondrial biogenesis in human gastric epithelium cells.
Archives of toxicology
Li Q,Dong Z,Lian W,Cui J,Wang J,Shen H,Liu W,Yang J,Zhang X,Cui H
Mon Apr 01 00:00:00 EDT 2019
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 EDT 2019
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
EBioMedicine
Shan H,Li T,Zhang L,Yang R,Li Y,Zhang M,Dong Y,Zhou Y,Xu C,Yang B,Liang H,Gao X,Shan H
Tue Jan 01 00:00:00 EST 2019
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
EBioMedicine
Shan H,Li T,Zhang L,Yang R,Li Y,Zhang M,Dong Y,Zhou Y,Xu C,Yang B,Liang H,Gao X,Shan H
Tue Jan 01 00:00:00 EST 2019
Protective Effects of Fucoxanthin against Alcoholic Liver Injury by Activation of Nrf2-Mediated Antioxidant Defense and Inhibition of TLR4-Mediated Inflammation.
Marine drugs
Zheng J,Tian X,Zhang W,Zheng P,Huang F,Ding G,Yang Z
Fri Sep 27 00:00:00 EDT 2019
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Oxidative medicine and cellular longevity
Zhang HF,Wang JH,Wang YL,Gao C,Gu YT,Huang J,Wang JH,Zhang Z
Thu Aug 08 00:00:00 EDT 2019
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
American journal of translational research
Lin J,Lin R,Li S,Wu H,Ding J,Xiang G,Li S,Wang Y,Lin D,Gao W,Kong J,Xu H,Zhou K
Tue Sep 29 00:00:00 EDT 2020
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
Frontiers in pharmacology
Li J,Bao G,ALyafeai E,Ding J,Li S,Sheng S,Shen Z,Jia Z,Lin C,Zhang C,Lou Z,Xu H,Gao W,Zhou K
Thu Oct 01 00:00:00 EDT 2020
Carnosol as a Nrf2 Activator Improves Endothelial Barrier Function Through Antioxidative Mechanisms.
International journal of molecular sciences
Li X,Zhang Q,Hou N,Li J,Liu M,Peng S,Zhang Y,Luo Y,Zhao B,Wang S,Zhang Y,Qiao Y
Mon Feb 18 00:00:00 EST 2019
Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway.
Molecules (Basel, Switzerland)
Jing L,Jiang JR,Liu DM,Sheng JW,Zhang WF,Li ZJ,Wei LY
Mon Sep 16 00:00:00 EDT 2019
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Neurotoxicology
Zhang C,Zhan J,Zhao M,Dai H,Deng Y,Zhou W,Zhao L
Sun Sep 01 00:00:00 EDT 2019
Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2-HMOX1 axis.
Veterinary research
Liu X,Song Z,Bai J,Nauwynck H,Zhao Y,Jiang P
Wed Sep 11 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Marine drugs
Lin F,Yang D,Huang Y,Zhao Y,Ye J,Xiao M
Fri Sep 20 00:00:00 EDT 2019
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Frontiers in pharmacology
Song S,Chu L,Liang H,Chen J,Liang J,Huang Z,Zhang B,Chen X
Thu Oct 01 00:00:00 EDT 2020
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway.
International journal of biological sciences
Wu H,Ding J,Li S,Lin J,Jiang R,Lin C,Dai L,Xie C,Lin D,Xu H,Gao W,Zhou K
Mon Jan 13 00:00:00 EST 2020
Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
ACS chemical neuroscience
Wang H,Wei W,Lan X,Liu N,Li Y,Ma H,Sun T,Peng X,Zhuang C,Yu J
Wed May 15 00:00:00 EDT 2019
Lipoamide Ameliorates Oxidative Stress via Induction of Nrf2/ARE Signaling Pathway in PC12 Cells.
Journal of agricultural and food chemistry
Hou Y,Li X,Peng S,Yao J,Bai F,Fang J
Wed Jul 24 00:00:00 EDT 2019
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Toxicology letters
Yao B,He J,Yin X,Shi Y,Wan J,Tian Z
Fri Nov 01 00:00:00 EDT 2019
The anti-nephritic activity of a polysaccharide from okra (Abelmoschus esculentus (L.) Moench) via modulation of AMPK-Sirt1-PGC-1α signaling axis mediated anti-oxidative in type 2 diabetes model mice.
International journal of biological macromolecules
Liao Z,Zhang J,Wang J,Yan T,Xu F,Wu B,Xiao F,Bi K,Niu J,Jia Y
Fri Nov 01 00:00:00 EDT 2019
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
International journal of molecular sciences
Wang Z,Liang M,Li H,Cai L,Yang L
Fri Dec 06 00:00:00 EST 2019
Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction.
Journal of medicinal chemistry
Zhou W,Ma L,Ding L,Guo Q,He Z,Yang J,Qiao H,Li L,Yang J,Yu S,Zhao L,Wang S,Liu HM,Suo Z,Zhao W
Thu Jun 13 00:00:00 EDT 2019
Dietary Dihydroartemisinin Supplementation Attenuates Hepatic Oxidative Damage of Weaned Piglets with Intrauterine Growth Retardation through the Nrf2/ARE Signaling Pathway.
Animals : an open access journal from MDPI
Zhao Y,Niu Y,He J,Zhang L,Wang C,Wang T
Fri Dec 13 00:00:00 EST 2019
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Brain sciences
Xu B,Lang LM,Lian S,Guo JR,Wang JF,Yang HM,Li SZ
Sat Oct 12 00:00:00 EDT 2019
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Pharmacological research
Zhao X,Jin Y,Li L,Xu L,Tang Z,Qi Y,Yin L,Peng J
Thu Aug 01 00:00:00 EDT 2019
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Neural regeneration research
Xie YK,Zhou X,Yuan HT,Qiu J,Xin DQ,Chu XL,Wang DC,Wang Z
Tue Oct 01 00:00:00 EDT 2019
CCl4-Induced Liver Injury Was Ameliorated by Qi-Ge Decoction through the Antioxidant Pathway.
Evidence-based complementary and alternative medicine : eCAM
Peng C,Zhou ZM,Li J,Luo Y,Zhou YS,Ke XH,Huang KE
Wed Sep 30 00:00:00 EDT 2020
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Thu Aug 01 00:00:00 EDT 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 EDT 2019
NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells.
Cancer letters
Peng D,Lu H,Zhu S,Zhou Z,Hu T,Chen Z,Zaika A,El-Rifai W
Wed Aug 28 00:00:00 EDT 2019
SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway.
Frontiers in oncology
Sun X,Wang S,Gai J,Guan J,Li J,Li Y,Zhao J,Zhao C,Fu L,Li Q
Tue Sep 29 00:00:00 EDT 2020
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
Kidney & blood pressure research
Zhang W,Yang Y,Gao H,Zhang Y,Jia Z,Huang S
Tue Mar 03 00:00:00 EST 2020
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Journal of bioenergetics and biomembranes
Li L,Liu T,Liu L,Li S,Zhang Z,Zhang R,Zhou Y,Liu F
Sun Dec 01 00:00:00 EST 2019
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Journal of bioenergetics and biomembranes
Li L,Liu T,Liu L,Li S,Zhang Z,Zhang R,Zhou Y,Liu F
Sun Dec 01 00:00:00 EST 2019
Nuclear factor (erythroid-derived 2)-like 2 antioxidative response mitigates cytoplasmic radiation-induced DNA double-strand breaks.
Cancer science
Wang J,Konishi T
Fri Feb 01 00:00:00 EST 2019
FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response.
Frontiers in pharmacology
Dong L,Li R,Li D,Wang B,Lu Y,Li P,Yu F,Jin Y,Ni X,Wu Y,Yang S,Lv G,Li X,Xiao J,Wang J
Thu Oct 01 00:00:00 EDT 2020
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Journal of ethnopharmacology
Lu Q,Tan S,Gu W,Li F,Hua W,Zhang S,Chen F,Tang L
Mon Oct 28 00:00:00 EDT 2019
The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity Reactions.
Drug metabolism and disposition: the biological fate of chemicals
Kato R,Ijiri Y,Hayashi T,Uetrecht J
Tue Oct 01 00:00:00 EDT 2019
CGRP Reduces Apoptosis of DRG Cells Induced by High-Glucose Oxidative Stress Injury through PI3K/AKT Induction of Heme Oxygenase-1 and Nrf-2 Expression.
Oxidative medicine and cellular longevity
Liu Y,Zhang S,Xue J,Wei Z,Ao P,Shen B,Ding L
Fri May 01 00:00:00 EDT 2020
The harmful effects of acute PM2.5 exposure to the heart and a novel preventive and therapeutic function of CEOs.
Scientific reports
Dong L,Sun W,Li F,Shi M,Meng X,Wang C,Meng M,Tang W,Liu H,Wang L,Song L
Tue Mar 05 00:00:00 EST 2019
Neuroprotective Effect of Dioscin on the Aging Brain.
Molecules (Basel, Switzerland)
Qi Y,Li R,Xu L,Yin L,Xu Y,Han X,Peng J
Sat Mar 30 00:00:00 EDT 2019
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Journal of the science of food and agriculture
Wang Z,Liang M,Li H,Cai L,He H,Wu Q,Yang L
Thu Aug 15 00:00:00 EDT 2019
Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis.
Neuroscience
Wang P,Zhao Y,Li Y,Wu J,Yu S,Zhu J,Li L,Zhao Y
Mon Jul 01 00:00:00 EDT 2019
Sodium/calcium overload and Sirt1/Nrf2/OH-1 pathway are critical events in mercuric chloride-induced nephrotoxicity.
Chemosphere
Li S,Jiang X,Luo Y,Zhou B,Shi M,Liu F,Sha A
Fri Nov 01 00:00:00 EDT 2019
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Metabolic brain disease
Gao W,Wang W,Zhang J,Deng P,Hu J,Yang J,Deng Z
Tue Oct 01 00:00:00 EDT 2019
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Metabolic brain disease
Gao W,Wang W,Zhang J,Deng P,Hu J,Yang J,Deng Z
Tue Oct 01 00:00:00 EDT 2019
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Experimental & molecular medicine
Xiao HW,Li Y,Luo D,Dong JL,Zhou LX,Zhao SY,Zheng QS,Wang HC,Cui M,Fan SJ
Fri Jan 26 00:00:00 EST 2018
Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88's effects on the gut microbiota.
Experimental & molecular medicine
Xiao HW,Li Y,Luo D,Dong JL,Zhou LX,Zhao SY,Zheng QS,Wang HC,Cui M,Fan SJ
Fri Jan 26 00:00:00 EST 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 EST 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 EST 2018
Liver injury induced in Balb/c mice by PM2.5 exposure and its alleviation by compound essential oils.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ya P,Xu H,Ma Y,Fang M,Yan X,Zhou J,Li F
Sat Sep 01 00:00:00 EDT 2018
Liver injury induced in Balb/c mice by PM2.5 exposure and its alleviation by compound essential oils.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ya P,Xu H,Ma Y,Fang M,Yan X,Zhou J,Li F
Sat Sep 01 00:00:00 EDT 2018
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Oxidative medicine and cellular longevity
Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J
Tue Sep 18 00:00:00 EDT 2018
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Oxidative medicine and cellular longevity
Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J
Tue Sep 18 00:00:00 EDT 2018
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Oxidative medicine and cellular longevity
Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J
Tue Sep 18 00:00:00 EDT 2018
Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.
Oxidative medicine and cellular longevity
Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J
Tue Sep 18 00:00:00 EDT 2018
Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway.
Acta pharmacologica Sinica
Li ST,Dai Q,Zhang SX,Liu YJ,Yu QQ,Tan F,Lu SH,Wang Q,Chen JW,Huang HQ,Liu PQ,Li M
Wed Aug 01 00:00:00 EDT 2018
Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway.
Acta pharmacologica Sinica
Li ST,Dai Q,Zhang SX,Liu YJ,Yu QQ,Tan F,Lu SH,Wang Q,Chen JW,Huang HQ,Liu PQ,Li M
Wed Aug 01 00:00:00 EDT 2018
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
Biochemical pharmacology
Wang K,Lv Q,Miao YM,Qiao SM,Dai Y,Wei ZF
Sat Sep 01 00:00:00 EDT 2018
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
Biochemical pharmacology
Wang K,Lv Q,Miao YM,Qiao SM,Dai Y,Wei ZF
Sat Sep 01 00:00:00 EDT 2018
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
T-2 toxin-induced toxicity in neuroblastoma-2a cells involves the generation of reactive oxygen, mitochondrial dysfunction and inhibition of Nrf2/HO-1 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhang X,Wang Y,Velkov T,Tang S,Dai C
Sun Apr 01 00:00:00 EDT 2018
Cyclooxygenase‑2‑mediated upregulation of heme oxygenase 1 mitigates the toxicity of deuterium‑tritium fusion radiation.
International journal of molecular medicine
Yang X,Liu H,Jiang X,Jin C,Xu Z,Li T,Wang Z,Wang J
Mon Oct 01 00:00:00 EDT 2018
Cyclooxygenase‑2‑mediated upregulation of heme oxygenase 1 mitigates the toxicity of deuterium‑tritium fusion radiation.
International journal of molecular medicine
Yang X,Liu H,Jiang X,Jin C,Xu Z,Li T,Wang Z,Wang J
Mon Oct 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling.
Toxicology and applied pharmacology
Dong W,Yang B,Wang L,Li B,Guo X,Zhang M,Jiang Z,Fu J,Pi J,Guan D,Zhao R
Tue May 01 00:00:00 EDT 2018
Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling.
Toxicology and applied pharmacology
Dong W,Yang B,Wang L,Li B,Guo X,Zhang M,Jiang Z,Fu J,Pi J,Guan D,Zhao R
Tue May 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
Environmental toxicology
Lin EY,Bayarsengee U,Wang CC,Chiang YH,Cheng CW
Mon Jan 01 00:00:00 EST 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 EDT 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson's Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function.
Frontiers in aging neuroscience
Li X,Cui XX,Chen YJ,Wu TT,Xu H,Yin H,Wu YC
Thu Oct 01 00:00:00 EDT 2020
Ribosomal protein L10 in mitochondria serves as a regulator for ROS level in pancreatic cancer cells.
Redox biology
Yang J,Chen Z,Liu N,Chen Y
Mon Oct 01 00:00:00 EDT 2018
Ribosomal protein L10 in mitochondria serves as a regulator for ROS level in pancreatic cancer cells.
Redox biology
Yang J,Chen Z,Liu N,Chen Y
Mon Oct 01 00:00:00 EDT 2018
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Frontiers in physiology
Gáll T,Pethő D,Nagy A,Hendrik Z,Méhes G,Potor L,Gram M,Åkerström B,Smith A,Nagy P,Balla G,Balla J
Wed Oct 04 00:00:00 EDT 2023
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Frontiers in physiology
Gáll T,Pethő D,Nagy A,Hendrik Z,Méhes G,Potor L,Gram M,Åkerström B,Smith A,Nagy P,Balla G,Balla J
Wed Oct 04 00:00:00 EDT 2023
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Medicine and science in sports and exercise
Wu C,Yang L,Tucker D,Dong Y,Zhu L,Duan R,Liu TC,Zhang Q
Tue May 01 00:00:00 EDT 2018
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Frontiers in pharmacology
Lin J,Lin R,Li S,Wu H,Ding J,Xiang G,Li S,Wang Y,Lin D,Gao W,Kong J,Xu H,Zhou K
Sat Nov 04 00:00:00 EDT 2023
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Frontiers in pharmacology
Lin J,Lin R,Li S,Wu H,Ding J,Xiang G,Li S,Wang Y,Lin D,Gao W,Kong J,Xu H,Zhou K
Sat Nov 04 00:00:00 EDT 2023
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Redox biology
Zhao L,Tao X,Qi Y,Xu L,Yin L,Peng J
Fri Jun 01 00:00:00 EDT 2018
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Redox biology
Zhao L,Tao X,Qi Y,Xu L,Yin L,Peng J
Fri Jun 01 00:00:00 EDT 2018
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge.
Journal of neuroinflammation
Paraiso HC,Kuo PC,Curfman ET,Moon HJ,Sweazey RD,Yen JH,Chang FL,Yu IC
Thu Mar 29 00:00:00 EDT 2018
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge.
Journal of neuroinflammation
Paraiso HC,Kuo PC,Curfman ET,Moon HJ,Sweazey RD,Yen JH,Chang FL,Yu IC
Thu Mar 29 00:00:00 EDT 2018
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Nature communications
Muliaditan T,Caron J,Okesola M,Opzoomer JW,Kosti P,Georgouli M,Gordon P,Lall S,Kuzeva DM,Pedro L,Shields JD,Gillett CE,Diebold SS,Sanz-Moreno V,Ng T,Hoste E,Arnold JN
Fri Jul 27 00:00:00 EDT 2018
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Nature communications
Muliaditan T,Caron J,Okesola M,Opzoomer JW,Kosti P,Georgouli M,Gordon P,Lall S,Kuzeva DM,Pedro L,Shields JD,Gillett CE,Diebold SS,Sanz-Moreno V,Ng T,Hoste E,Arnold JN
Fri Jul 27 00:00:00 EDT 2018
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Nature communications
Muliaditan T,Caron J,Okesola M,Opzoomer JW,Kosti P,Georgouli M,Gordon P,Lall S,Kuzeva DM,Pedro L,Shields JD,Gillett CE,Diebold SS,Sanz-Moreno V,Ng T,Hoste E,Arnold JN
Fri Jul 27 00:00:00 EDT 2018
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Nature communications
Muliaditan T,Caron J,Okesola M,Opzoomer JW,Kosti P,Georgouli M,Gordon P,Lall S,Kuzeva DM,Pedro L,Shields JD,Gillett CE,Diebold SS,Sanz-Moreno V,Ng T,Hoste E,Arnold JN
Fri Jul 27 00:00:00 EDT 2018
Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2.
ACS chemical neuroscience
Hou Y,Peng S,Li X,Yao J,Xu J,Fang J
Wed Dec 19 00:00:00 EST 2018
Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2.
ACS chemical neuroscience
Hou Y,Peng S,Li X,Yao J,Xu J,Fang J
Wed Dec 19 00:00:00 EST 2018
3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway.
Brain, behavior, and immunity
Kuo PC,Yu IC,Scofield BA,Brown DA,Curfman ET,Paraiso HC,Chang FL,Yen JH
Mon May 01 00:00:00 EDT 2017
3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway.
Brain, behavior, and immunity
Kuo PC,Yu IC,Scofield BA,Brown DA,Curfman ET,Paraiso HC,Chang FL,Yen JH
Mon May 01 00:00:00 EDT 2017
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Biomaterials
Gao M,Zhao B,Chen M,Liu Y,Xu M,Wang Z,Liu S,Zhang C
Thu Jun 01 00:00:00 EDT 2017
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Biomaterials
Gao M,Zhao B,Chen M,Liu Y,Xu M,Wang Z,Liu S,Zhang C
Thu Jun 01 00:00:00 EDT 2017
Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis.
Cancer research
Marelli G,Erreni M,Anselmo A,Taverniti V,Guglielmetti S,Mantovani A,Allavena P
Tue Aug 15 00:00:00 EDT 2017
Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis.
Cancer research
Marelli G,Erreni M,Anselmo A,Taverniti V,Guglielmetti S,Mantovani A,Allavena P
Tue Aug 15 00:00:00 EDT 2017
Establishment and characterization of human osteosarcoma cells resistant to pyropheophorbide-α methyl ester-mediated photodynamic therapy.
International journal of oncology
Tao Y,Ou Y,Yin H,Chen Y,Zhong S,Gao Y,Zhao Z,He B,Huang Q,Deng Q
Wed Nov 01 00:00:00 EDT 2017
Establishment and characterization of human osteosarcoma cells resistant to pyropheophorbide-α methyl ester-mediated photodynamic therapy.
International journal of oncology
Tao Y,Ou Y,Yin H,Chen Y,Zhong S,Gao Y,Zhao Z,He B,Huang Q,Deng Q
Wed Nov 01 00:00:00 EDT 2017
Vitamin E antagonizes ozone-induced asthma exacerbation in Balb/c mice through the Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Duan L,Li J,Ma P,Yang X,Xu S
Fri Sep 01 00:00:00 EDT 2017
Vitamin E antagonizes ozone-induced asthma exacerbation in Balb/c mice through the Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Duan L,Li J,Ma P,Yang X,Xu S
Fri Sep 01 00:00:00 EDT 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 EST 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 EST 2017
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li D,Dai C,Yang X,Wang F,Yu X,Xiao X,Tang S
Sun Oct 01 00:00:00 EDT 2017
Critical role of p21 on olaquindox-induced mitochondrial apoptosis and S-phase arrest involves activation of PI3K/AKT and inhibition of Nrf2/HO-1pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Li D,Dai C,Yang X,Wang F,Yu X,Xiao X,Tang S
Sun Oct 01 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Reduction of oxidative damages induced by titanium dioxide nanoparticles correlates with induction of the Nrf2 pathway by GSPE supplementation in mice.
Chemico-biological interactions
Niu L,Shao M,Liu Y,Hu J,Li R,Xie H,Zhou L,Shi L,Zhang R,Niu Y
Mon Sep 25 00:00:00 EDT 2017
Reduction of oxidative damages induced by titanium dioxide nanoparticles correlates with induction of the Nrf2 pathway by GSPE supplementation in mice.
Chemico-biological interactions
Niu L,Shao M,Liu Y,Hu J,Li R,Xie H,Zhou L,Shi L,Zhang R,Niu Y
Mon Sep 25 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
Geniposide protects pancreatic β cells from high glucose-mediated injury by activation of AMP-activated protein kinase.
Cell biology international
Liu C,Hao Y,Yin F,Zhang Y,Liu J
Mon May 01 00:00:00 EDT 2017
Geniposide protects pancreatic β cells from high glucose-mediated injury by activation of AMP-activated protein kinase.
Cell biology international
Liu C,Hao Y,Yin F,Zhang Y,Liu J
Mon May 01 00:00:00 EDT 2017
Role of the cystathionine β-synthase/H2S system in liver cancer cells and the inhibitory effect of quinolone-indolone conjugate QIC2 on the system.
Oncology reports
Jia H,Ye J,You J,Shi X,Kang W,Wang T
Mon May 01 00:00:00 EDT 2017
Role of the cystathionine β-synthase/H2S system in liver cancer cells and the inhibitory effect of quinolone-indolone conjugate QIC2 on the system.
Oncology reports
Jia H,Ye J,You J,Shi X,Kang W,Wang T
Mon May 01 00:00:00 EDT 2017
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Toxicology mechanisms and methods
Dai C,Lei L,Li B,Lin Y,Xiao X,Tang S
Wed Mar 01 00:00:00 EST 2017
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Toxicology mechanisms and methods
Dai C,Lei L,Li B,Lin Y,Xiao X,Tang S
Wed Mar 01 00:00:00 EST 2017
Effect of ozone oxidative preconditioning on oxidative stress injury in a rat model of kidney transplantation.
Experimental and therapeutic medicine
Qiu T,Wang ZS,Liu XH,Chen H,Zhou JQ,Chen ZY,Wang M,Jiang GJ,Wang L,Yu G,Zhang L,Shen Y,Zhang L,He L,Wang HX,Zhang WJ
Mon May 01 00:00:00 EDT 2017
Effect of ozone oxidative preconditioning on oxidative stress injury in a rat model of kidney transplantation.
Experimental and therapeutic medicine
Qiu T,Wang ZS,Liu XH,Chen H,Zhou JQ,Chen ZY,Wang M,Jiang GJ,Wang L,Yu G,Zhang L,Shen Y,Zhang L,He L,Wang HX,Zhang WJ
Mon May 01 00:00:00 EDT 2017
Effect of ozone oxidative preconditioning on oxidative stress injury in a rat model of kidney transplantation.
Experimental and therapeutic medicine
Qiu T,Wang ZS,Liu XH,Chen H,Zhou JQ,Chen ZY,Wang M,Jiang GJ,Wang L,Yu G,Zhang L,Shen Y,Zhang L,He L,Wang HX,Zhang WJ
Mon May 01 00:00:00 EDT 2017
Effect of ozone oxidative preconditioning on oxidative stress injury in a rat model of kidney transplantation.
Experimental and therapeutic medicine
Qiu T,Wang ZS,Liu XH,Chen H,Zhou JQ,Chen ZY,Wang M,Jiang GJ,Wang L,Yu G,Zhang L,Shen Y,Zhang L,He L,Wang HX,Zhang WJ
Mon May 01 00:00:00 EDT 2017
The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms.
Experimental and therapeutic medicine
Li L,Kong L,Song H
Fri Sep 01 00:00:00 EDT 2017
The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms.
Experimental and therapeutic medicine
Li L,Kong L,Song H
Fri Sep 01 00:00:00 EDT 2017
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhao Z,Lu Z,Sun X,Zhao T,Zhang J,Zhou C,Zheng X,Zhang H,Shi G
Sat Jul 01 00:00:00 EDT 2017
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhao Z,Lu Z,Sun X,Zhao T,Zhang J,Zhou C,Zheng X,Zhang H,Shi G
Sat Jul 01 00:00:00 EDT 2017
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang Y,Wang W,Xu H,Sun Y,Sun J,Jiang Y,Yao J,Tian Y
Tue Jul 11 00:00:00 EDT 2017
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang Y,Wang W,Xu H,Sun Y,Sun J,Jiang Y,Yao J,Tian Y
Tue Jul 11 00:00:00 EDT 2017
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang Y,Wang W,Xu H,Sun Y,Sun J,Jiang Y,Yao J,Tian Y
Tue Jul 11 00:00:00 EDT 2017
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang Y,Wang W,Xu H,Sun Y,Sun J,Jiang Y,Yao J,Tian Y
Tue Jul 11 00:00:00 EDT 2017
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Redox biology
Liu S,Xin D,Wang L,Zhang T,Bai X,Li T,Xie Y,Xue H,Bo S,Liu D,Wang Z
Sun Oct 01 00:00:00 EDT 2017
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Redox biology
Liu S,Xin D,Wang L,Zhang T,Bai X,Li T,Xie Y,Xue H,Bo S,Liu D,Wang Z
Sun Oct 01 00:00:00 EDT 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis.
The Journal of biological chemistry
Lu J,Guo S,Xue X,Chen Q,Ge J,Zhuo Y,Zhong H,Chen B,Zhao M,Han W,Suzuki T,Zhu M,Xia L,Schneider C,Blackwell TS,Porter NA,Zheng L,Tsimikas S,Yin H
Fri Mar 31 00:00:00 EDT 2017
Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis.
The Journal of biological chemistry
Lu J,Guo S,Xue X,Chen Q,Ge J,Zhuo Y,Zhong H,Chen B,Zhao M,Han W,Suzuki T,Zhu M,Xia L,Schneider C,Blackwell TS,Porter NA,Zheng L,Tsimikas S,Yin H
Fri Mar 31 00:00:00 EDT 2017
(-)-7(S)-hydroxymatairesinol protects against tumor necrosis factor-α-mediated inflammation response in endothelial cells by blocking the MAPK/NF-κB and activating Nrf2/HO-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang D,Xiao CX,Su ZH,Huang MW,Qin M,Wu WJ,Jia WW,Zhu YZ,Hu JF,Liu XH
Tue Aug 15 00:00:00 EDT 2017
(-)-7(S)-hydroxymatairesinol protects against tumor necrosis factor-α-mediated inflammation response in endothelial cells by blocking the MAPK/NF-κB and activating Nrf2/HO-1.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang D,Xiao CX,Su ZH,Huang MW,Qin M,Wu WJ,Jia WW,Zhu YZ,Hu JF,Liu XH
Tue Aug 15 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Redox biology
Zhang C,Li C,Chen S,Li Z,Jia X,Wang K,Bao J,Liang Y,Wang X,Chen M,Li P,Su H,Wan JB,Lee SMY,Liu K,He C
Sat Apr 01 00:00:00 EDT 2017
Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways.
Redox biology
Zhang C,Li C,Chen S,Li Z,Jia X,Wang K,Bao J,Liang Y,Wang X,Chen M,Li P,Su H,Wan JB,Lee SMY,Liu K,He C
Sat Apr 01 00:00:00 EDT 2017
Potential Ameliorative Effects of Qing Ye Dan Against Cadmium Induced Prostatic Deficits via Regulating Nrf-2/HO-1 and TGF-β1/Smad Pathways.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Du L,Lei Y,Chen J,Song H,Wu X
Mon Dec 18 00:00:00 EST 2017
Potential Ameliorative Effects of Qing Ye Dan Against Cadmium Induced Prostatic Deficits via Regulating Nrf-2/HO-1 and TGF-β1/Smad Pathways.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Du L,Lei Y,Chen J,Song H,Wu X
Mon Dec 18 00:00:00 EST 2017
3H-1,2-dithiole-3-thione as a novel therapeutic agent for the treatment of experimental autoimmune encephalomyelitis.
Brain, behavior, and immunity
Kuo PC,Brown DA,Scofield BA,Yu IC,Chang FL,Wang PY,Yen JH
Sat Oct 01 00:00:00 EDT 2016
3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice.
Free radical biology & medicine
Lu L,Dong J,Li D,Zhang J,Fan S
Sat Oct 01 00:00:00 EDT 2016
3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice.
Free radical biology & medicine
Lu L,Dong J,Li D,Zhang J,Fan S
Sat Oct 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Li W,Ma F,Zhang L,Huang Y,Li X,Zhang A,Hou C,Zhu Y,Zhu Y
Mon Mar 13 00:00:00 EDT 2017
S-Propargyl-cysteine Exerts a Novel Protective Effect on Methionine and Choline Deficient Diet-Induced Fatty Liver via Akt/Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Li W,Ma F,Zhang L,Huang Y,Li X,Zhang A,Hou C,Zhu Y,Zhu Y
Mon Mar 13 00:00:00 EDT 2017
Protective Effects of Hydrogen Sulfide in the Ageing Kidney.
Oxidative medicine and cellular longevity
Hou CL,Wang MJ,Sun C,Huang Y,Jin S,Mu XP,Chen Y,Zhu YC
Mon Mar 13 00:00:00 EDT 2017
Protective Effects of Hydrogen Sulfide in the Ageing Kidney.
Oxidative medicine and cellular longevity
Hou CL,Wang MJ,Sun C,Huang Y,Jin S,Mu XP,Chen Y,Zhu YC
Mon Mar 13 00:00:00 EDT 2017
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 EDT 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 EDT 2016
Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity.
Neurochemistry international
Yu G,Deng A,Tang W,Ma J,Yuan C,Ma J
Wed Jun 01 00:00:00 EDT 2016
Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity.
Neurochemistry international
Yu G,Deng A,Tang W,Ma J,Yuan C,Ma J
Wed Jun 01 00:00:00 EDT 2016
Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats.
Gene
Li H,He H,Wang Z,Cai J,Sun B,Wu Q,Zhang Y,Zhou G,Yang L
Sun Jul 10 00:00:00 EDT 2016
Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats.
Gene
Li H,He H,Wang Z,Cai J,Sun B,Wu Q,Zhang Y,Zhou G,Yang L
Sun Jul 10 00:00:00 EDT 2016
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Renal failure
Zhang W,Li Y,Ding H,Du Y,Wang L
Mon Aug 01 00:00:00 EDT 2016
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Renal failure
Zhang W,Li Y,Ding H,Du Y,Wang L
Mon Aug 01 00:00:00 EDT 2016
High expression of heme oxygenase-1 in target organs may attenuate acute graft-versus-host disease through regulation of immune balance of TH17/Treg.
Transplant immunology
Yu M,Wang J,Fang Q,Liu P,Chen S,Zhe N,Lin X,Zhang Y,Zhao J,Zhou Z
Fri Jul 01 00:00:00 EDT 2016
High expression of heme oxygenase-1 in target organs may attenuate acute graft-versus-host disease through regulation of immune balance of TH17/Treg.
Transplant immunology
Yu M,Wang J,Fang Q,Liu P,Chen S,Zhe N,Lin X,Zhang Y,Zhao J,Zhou Z
Fri Jul 01 00:00:00 EDT 2016
Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1.
Cell death & disease
Kang H,Yan Y,Jia P,Yang K,Guo C,Chen H,Qi J,Qian N,Xu X,Wang F,Li C,Guo L,Deng L
Thu Oct 27 00:00:00 EDT 2016
Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1.
Cell death & disease
Kang H,Yan Y,Jia P,Yang K,Guo C,Chen H,Qi J,Qian N,Xu X,Wang F,Li C,Guo L,Deng L
Thu Oct 27 00:00:00 EDT 2016
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Scientific reports
Hu B,Shi C,Xu C,Cao P,Tian Y,Zhang Y,Deng L,Chen H,Yuan W
Mon Feb 15 00:00:00 EST 2016
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Scientific reports
Hu B,Shi C,Xu C,Cao P,Tian Y,Zhang Y,Deng L,Chen H,Yuan W
Mon Feb 15 00:00:00 EST 2016
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Scientific reports
Hu B,Shi C,Xu C,Cao P,Tian Y,Zhang Y,Deng L,Chen H,Yuan W
Mon Feb 15 00:00:00 EST 2016
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Scientific reports
Hu B,Shi C,Xu C,Cao P,Tian Y,Zhang Y,Deng L,Chen H,Yuan W
Mon Feb 15 00:00:00 EST 2016
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Molecules (Basel, Switzerland)
Zhao L,Xu L,Tao X,Han X,Yin L,Qi Y,Peng J
Thu Jul 21 00:00:00 EDT 2016
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Molecules (Basel, Switzerland)
Zhao L,Xu L,Tao X,Han X,Yin L,Qi Y,Peng J
Thu Jul 21 00:00:00 EDT 2016
Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats.
Frontiers in cellular neuroscience
Hu Q,Li T,Wang L,Xie Y,Liu S,Bai X,Zhang T,Bo S,Xin D,Xue H,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats.
Frontiers in cellular neuroscience
Hu Q,Li T,Wang L,Xie Y,Liu S,Bai X,Zhang T,Bo S,Xin D,Xue H,Li G,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
PloS one
Gao Z,Han Y,Hu Y,Wu X,Wang Y,Zhang X,Fu J,Zou X,Zhang J,Chen X,Jose PA,Lu X,Zeng C
Mon Jul 25 00:00:00 EDT 2016
Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways.
PloS one
Gao Z,Han Y,Hu Y,Wu X,Wang Y,Zhang X,Fu J,Zou X,Zhang J,Chen X,Jose PA,Lu X,Zeng C
Mon Jul 25 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Free radical research
Nie H,Xue X,Liu G,Guan G,Liu H,Sun L,Zhao L,Wang X,Chen Z
Thu Feb 09 00:00:00 EST 2017
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Free radical research
Nie H,Xue X,Liu G,Guan G,Liu H,Sun L,Zhao L,Wang X,Chen Z
Thu Feb 09 00:00:00 EST 2017
Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice.
Toxicology research
Zhu Y,Li J,Wu Z,Lu Y,You H,Li R,Li B,Yang X,Duan L
Fri Jan 01 00:00:00 EST 2016
Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo.
Journal of hazardous materials
Shi Z,Niu Y,Wang Q,Shi L,Guo H,Liu Y,Zhu Y,Liu S,Liu C,Chen X,Zhang R
Sun Nov 15 00:00:00 EST 2015
Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo.
Journal of hazardous materials
Shi Z,Niu Y,Wang Q,Shi L,Guo H,Liu Y,Zhu Y,Liu S,Liu C,Chen X,Zhang R
Sun Nov 15 00:00:00 EST 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Bioscience reports
Yang R,Zhang M,Gustafson AR,Wang E,Cole MP,Tooley CE,Cheng A
Fri May 01 00:00:00 EDT 2015
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Bioscience reports
Yang R,Zhang M,Gustafson AR,Wang E,Cole MP,Tooley CE,Cheng A
Fri May 01 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 EDT 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
ROS/Autophagy/Nrf2 Pathway Mediated Low-Dose Radiation Induced Radio-Resistance in Human Lung Adenocarcinoma A549 Cell.
International journal of biological sciences
Chen N,Wu L,Yuan H,Wang J
Tue Mar 15 00:00:00 EDT 2016
ROS/Autophagy/Nrf2 Pathway Mediated Low-Dose Radiation Induced Radio-Resistance in Human Lung Adenocarcinoma A549 Cell.
International journal of biological sciences
Chen N,Wu L,Yuan H,Wang J
Tue Mar 15 00:00:00 EDT 2016
tert-Butylhydroquinone mobilizes intracellular-bound zinc to stabilize Nrf2 through inhibiting phosphatase activity.
American journal of physiology. Cell physiology
Chen Y,Wang S,Fu X,Zhou W,Hong W,Zou D,Li X,Liu J,Ran P,Li B
Sat Aug 01 00:00:00 EDT 2015
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells to arsenic trioxide.
Molecular and cellular biochemistry
Zhong L,Wang Y,Li W,Gu J,Li X,Wang X,Yue Z,Mu Y,Bai J,Li R,Zhang H
Tue Jul 01 00:00:00 EDT 2014
Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells to arsenic trioxide.
Molecular and cellular biochemistry
Zhong L,Wang Y,Li W,Gu J,Li X,Wang X,Yue Z,Mu Y,Bai J,Li R,Zhang H
Tue Jul 01 00:00:00 EDT 2014
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 EDT 2015
Inhibition of NADPH oxidase 4-related signaling by sodium hydrosulfide attenuates myocardial fibrotic response.
International journal of cardiology
Pan LL,Liu XH,Shen YQ,Wang NZ,Xu J,Wu D,Xiong QH,Deng HY,Huang GY,Zhu YZ
Wed Oct 09 00:00:00 EDT 2013
Inhibition of NADPH oxidase 4-related signaling by sodium hydrosulfide attenuates myocardial fibrotic response.
International journal of cardiology
Pan LL,Liu XH,Shen YQ,Wang NZ,Xu J,Wu D,Xiong QH,Deng HY,Huang GY,Zhu YZ
Wed Oct 09 00:00:00 EDT 2013
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Infection and immunity
Silva-Gomes S,Appelberg R,Larsen R,Soares MP,Gomes MS
Mon Jul 01 00:00:00 EDT 2013
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Infection and immunity
Silva-Gomes S,Appelberg R,Larsen R,Soares MP,Gomes MS
Mon Jul 01 00:00:00 EDT 2013
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Infection and immunity
Silva-Gomes S,Appelberg R,Larsen R,Soares MP,Gomes MS
Mon Jul 01 00:00:00 EDT 2013
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection.
Infection and immunity
Silva-Gomes S,Appelberg R,Larsen R,Soares MP,Gomes MS
Mon Jul 01 00:00:00 EDT 2013
Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of reactive oxygen species and NF-κB pathways.
European journal of pharmacology
Liu XH,Pan LL,Yang HB,Gong QH,Zhu YZ
Thu Apr 05 00:00:00 EDT 2012
Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of reactive oxygen species and NF-κB pathways.
European journal of pharmacology
Liu XH,Pan LL,Yang HB,Gong QH,Zhu YZ
Thu Apr 05 00:00:00 EDT 2012
Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice.
World journal of diabetes
He HJ,Wang GY,Gao Y,Ling WH,Yu ZW,Jin TR
Tue May 15 00:00:00 EDT 2012
Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice.
World journal of diabetes
He HJ,Wang GY,Gao Y,Ling WH,Yu ZW,Jin TR
Tue May 15 00:00:00 EDT 2012
Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium.
Journal of clinical pathology
Song G,Cui Y,Zhong N,Han J
Tue Sep 01 00:00:00 EDT 2009
Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium.
Journal of clinical pathology
Song G,Cui Y,Zhong N,Han J
Tue Sep 01 00:00:00 EDT 2009
Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC.
Proteomics
Chen N,Sun W,Deng X,Hao Y,Chen X,Xing B,Jia W,Ma J,Wei H,Zhu Y,Qian X,Jiang Y,He F
Mon Dec 01 00:00:00 EST 2008
Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC.
Proteomics
Chen N,Sun W,Deng X,Hao Y,Chen X,Xing B,Jia W,Ma J,Wei H,Zhu Y,Qian X,Jiang Y,He F
Mon Dec 01 00:00:00 EST 2008
