Product References
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane.
Biomedicines
Swaih AM,Breda C,Sathyasaikumar KV,Allcock N,Collier MEW,Mason RP,Feasby A,Herrera F,Outeiro TF,Schwarcz R,Repici M,Giorgini F
Thu Sep 15 00:00:00 EDT 2022
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane.
Biomedicines
Swaih AM,Breda C,Sathyasaikumar KV,Allcock N,Collier MEW,Mason RP,Feasby A,Herrera F,Outeiro TF,Schwarcz R,Repici M,Giorgini F
Thu Sep 15 00:00:00 EDT 2022
Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T-cell suppression.
Molecular oncology
Itoh G,Takagane K,Fukushi Y,Kuriyama S,Umakoshi M,Goto A,Yanagihara K,Yashiro M,Tanaka M
Sat Jan 01 00:00:00 EST 2022
Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans.
Journal of internal medicine
Baumgartner R,Berg M,Matic L,Polyzos KP,Forteza MJ,Hjorth SA,Schwartz TW,Paulsson-Berne G,Hansson GK,Hedin U,Ketelhuth DFJ
Fri Jan 01 00:00:00 EST 2021
Kynurenine 3-monooxygenase (KMO), and signal transducer and activator of transcription 3 (STAT3) expression is involved in tumour proliferation and predicts poor survival in canine melanoma.
Veterinary and comparative oncology
Liu IL,Chung TF,Huang WH,Hsu CH,Liu CC,Chiu YH,Huang KC,Liao AT,Lin CS
Mon Mar 01 00:00:00 EST 2021
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
Chemical research in toxicology
Tan B,Chen J,Qin S,Liao C,Zhang Y,Wang D,Li S,Zhang Z,Zhang P,Xu F
Mon Jul 19 00:00:00 EDT 2021
Surface Expression of Kynurenine 3-Monooxygenase Promotes Proliferation and Metastasis in Triple-Negative Breast Cancers.
Cancer control : journal of the Moffitt Cancer Center
Lai MH,Liao CH,Tsai NM,Chang KF,Liu CC,Chiu YH,Huang KC,Lin CS
Thu Nov 04 00:00:00 EDT 2021
Surface Expression of Kynurenine 3-Monooxygenase Promotes Proliferation and Metastasis in Triple-Negative Breast Cancers.
Cancer control : journal of the Moffitt Cancer Center
Lai MH,Liao CH,Tsai NM,Chang KF,Liu CC,Chiu YH,Huang KC,Lin CS
Thu Nov 04 00:00:00 EDT 2021
Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity.
Oncology letters
Morita N,Hoshi M,Hara T,Ninomiya S,Enoki T,Yoneda M,Tsurumi H,Saito K
Mon Nov 01 00:00:00 EDT 2021
Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity.
Oncology letters
Morita N,Hoshi M,Hara T,Ninomiya S,Enoki T,Yoneda M,Tsurumi H,Saito K
Mon Nov 01 00:00:00 EDT 2021
3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
ImmunoHorizons
Hoshi M,Kubo H,Ando T,Tashita C,Nakamoto K,Yamamoto Y,Tezuka H,Saito K
Mon Jun 28 00:00:00 EDT 2021
3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
ImmunoHorizons
Hoshi M,Kubo H,Ando T,Tashita C,Nakamoto K,Yamamoto Y,Tezuka H,Saito K
Mon Jun 28 00:00:00 EDT 2021
3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
ImmunoHorizons
Hoshi M,Kubo H,Ando T,Tashita C,Nakamoto K,Yamamoto Y,Tezuka H,Saito K
Mon Jun 28 00:00:00 EDT 2021
A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics.
PLoS genetics
Maddison DC,Alfonso-Núñez M,Swaih AM,Breda C,Campesan S,Allcock N,Straatman-Iwanowska A,Kyriacou CP,Giorgini F
Sun Nov 01 00:00:00 EDT 2020
Fr‑HMGB1 and ds‑HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive‑like behavior.
Molecular medicine reports
Wang B,Lian YJ,Su WJ,Liu LL,Li JM,Jiang CL,Wang YX
Mon Jul 01 00:00:00 EDT 2019
Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors.
Journal of oncology
Chiu YH,Lei HJ,Huang KC,Chiang YL,Lin CS
Thu Oct 01 00:00:00 EDT 2020
Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors.
Journal of oncology
Chiu YH,Lei HJ,Huang KC,Chiang YL,Lin CS
Thu Oct 01 00:00:00 EDT 2020
The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis.
Brain research
Xu G,Liu X,Wang Y
Sat Sep 15 00:00:00 EDT 2018
The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis.
Brain research
Xu G,Liu X,Wang Y
Sat Sep 15 00:00:00 EDT 2018
The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis.
Brain research
Xu G,Liu X,Wang Y
Sat Sep 15 00:00:00 EDT 2018
The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis.
Brain research
Xu G,Liu X,Wang Y
Sat Sep 15 00:00:00 EDT 2018
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.
Brain, behavior, and immunity
Laumet G,Zhou W,Dantzer R,Edralin JD,Huo X,Budac DP,O'Connor JC,Lee AW,Heijnen CJ,Kavelaars A
Wed Nov 01 00:00:00 EDT 2017
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.
Brain, behavior, and immunity
Laumet G,Zhou W,Dantzer R,Edralin JD,Huo X,Budac DP,O'Connor JC,Lee AW,Heijnen CJ,Kavelaars A
Wed Nov 01 00:00:00 EDT 2017
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.
Brain, behavior, and immunity
Laumet G,Zhou W,Dantzer R,Edralin JD,Huo X,Budac DP,O'Connor JC,Lee AW,Heijnen CJ,Kavelaars A
Wed Nov 01 00:00:00 EDT 2017
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.
Brain, behavior, and immunity
Laumet G,Zhou W,Dantzer R,Edralin JD,Huo X,Budac DP,O'Connor JC,Lee AW,Heijnen CJ,Kavelaars A
Wed Nov 01 00:00:00 EDT 2017
Central Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid Production.
Journal of virology
Formisano S,Hornig M,Yaddanapudi K,Vasishtha M,Parsons LH,Briese T,Lipkin WI,Williams BL
Sat Jul 15 00:00:00 EDT 2017
Central Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid Production.
Journal of virology
Formisano S,Hornig M,Yaddanapudi K,Vasishtha M,Parsons LH,Briese T,Lipkin WI,Williams BL
Sat Jul 15 00:00:00 EDT 2017
Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina.
Investigative ophthalmology & visual science
Hu P,Hunt NH,Arfuso F,Shaw LC,Uddin MN,Zhu M,Devasahayam R,Adamson SJ,Benson VL,Chan-Ling T,Grant MB
Sun Oct 01 00:00:00 EDT 2017
Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina.
Investigative ophthalmology & visual science
Hu P,Hunt NH,Arfuso F,Shaw LC,Uddin MN,Zhu M,Devasahayam R,Adamson SJ,Benson VL,Chan-Ling T,Grant MB
Sun Oct 01 00:00:00 EDT 2017
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.
Journal of the American Society of Nephrology : JASN
Korstanje R,Deutsch K,Bolanos-Palmieri P,Hanke N,Schroder P,Staggs L,Bräsen JH,Roberts IS,Sheehan S,Savage H,Haller H,Schiffer M
Tue Nov 01 00:00:00 EDT 2016
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.
Journal of the American Society of Nephrology : JASN
Korstanje R,Deutsch K,Bolanos-Palmieri P,Hanke N,Schroder P,Staggs L,Bräsen JH,Roberts IS,Sheehan S,Savage H,Haller H,Schiffer M
Tue Nov 01 00:00:00 EDT 2016
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.
Journal of the American Society of Nephrology : JASN
Korstanje R,Deutsch K,Bolanos-Palmieri P,Hanke N,Schroder P,Staggs L,Bräsen JH,Roberts IS,Sheehan S,Savage H,Haller H,Schiffer M
Tue Nov 01 00:00:00 EDT 2016
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Neuropharmacology
Rojewska E,Piotrowska A,Makuch W,Przewlocka B,Mika J
Tue Mar 01 00:00:00 EST 2016
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Neuropharmacology
Rojewska E,Piotrowska A,Makuch W,Przewlocka B,Mika J
Tue Mar 01 00:00:00 EST 2016
Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma.
Molecular imaging
Guastella AR,Michelhaugh SK,Klinger NV,Kupsky WJ,Polin LA,Muzik O,Juhász C,Mittal S
Tue Dec 13 00:00:00 EST 2016
Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma.
Molecular imaging
Guastella AR,Michelhaugh SK,Klinger NV,Kupsky WJ,Polin LA,Muzik O,Juhász C,Mittal S
Tue Dec 13 00:00:00 EST 2016
Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma.
Molecular imaging
Guastella AR,Michelhaugh SK,Klinger NV,Kupsky WJ,Polin LA,Muzik O,Juhász C,Mittal S
Tue Dec 13 00:00:00 EST 2016
Activation of NAD(P)H oxidase by tryptophan-derived 3-hydroxykynurenine accelerates endothelial apoptosis and dysfunction in vivo.
Circulation research
Wang Q,Zhang M,Ding Y,Wang Q,Zhang W,Song P,Zou MH
Fri Jan 31 00:00:00 EST 2014
Activation of NAD(P)H oxidase by tryptophan-derived 3-hydroxykynurenine accelerates endothelial apoptosis and dysfunction in vivo.
Circulation research
Wang Q,Zhang M,Ding Y,Wang Q,Zhang W,Song P,Zou MH
Fri Jan 31 00:00:00 EST 2014
Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO).
Journal of biomolecular screening
Winkler D,Beconi M,Toledo-Sherman LM,Prime M,Ebneth A,Dominguez C,Muñoz-Sanjuan I
Sun Sep 01 00:00:00 EDT 2013
Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO).
Journal of biomolecular screening
Winkler D,Beconi M,Toledo-Sherman LM,Prime M,Ebneth A,Dominguez C,Muñoz-Sanjuan I
Sun Sep 01 00:00:00 EDT 2013
