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Kallikrein 1 Antibody (PA5-116798) in IHC (P)
Immunohistochemistry analysis of Kallikrein 1 in paraffin-embedded human colon carcinoma. Samples were incubated with Kallikrein 1 Polyclonal antibody (Product # PA5-116798) using a dilution of 1:500 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-116798
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-262 of human KLK1 (NP_0022481)
Conjugate
Form
Liquid
Concentration
1.58 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901429
Product Specific Information
Positive Samples: SW480, K-562
Immunogen sequence: IVGGWECEQH SQPWQAALYH FSTFQCGGIL VHRQWVLTAA HCISDNYQLW LGRHNLFDDE NTAQFVHVSE SFPHPGFNMS LLENHTRQAD EDYSHDLMLL RLTEPADTIT DAVKVVELPT EEPEVGSTCL ASGWGSIEPE NFSFPDDLQC VDLKILPNDE CKKAHVQKVT DFMLCVGHLE GGKDTCVGDS GGPLMCDGVL QGVTSWGYVP CGTPNKPSVA VRVLSYVKWI EDTIAENS
Target Information
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7S nerve growth factor gamma chain; 7S nerve growth factor gamma subunit; Esterase B; Gamma-NGF; glandular kallikrein 1; Glandular kallikrein K1; Glandular kallikrein K3; Glandular kallikrein-7, submandibular/renal; KAL-B; Kallikrein 1 renal/pancreas/salivary; Kallikrein 1, renal/pancreas/salivary; kallikrein 1-like peptidase; Kallikrein 1-related peptidase b3; kallikrein 5; kallikrein 6; kallikrein 7; kallikrein renal/pancreas/salivary; kallikrein serine protease 1; Kallikrein-1; Kallikrein-related protein K1; Kidney/pancreas/salivary gland kallikrein; mGK-3; mGK-6; Nerve growth factor gamma chain; nerve growth factor gamma polypeptide; nerve growth factor, gamma; Pancreatic kallikrein; Proteinase A; PS kallikrein; Renal kallikrein; RGK-1; rGK-7; rK-1; RSKG-7; Tissue kallikrein; Tissue kallikrein-3; Tissue kallikrein-6; True kallikrein; True tissue kallikrein
Gene Aliases: 0610007D04Rik; hK1; Kal; KALA; Klk-1; Klk-3; Klk-6; Klk-7; KLK1; Klk1b3; Klk1b6; Klk1c1; Klk1l; Klk3; Klk5; Klk6; Klk7; KLKR; mGk-3; mGk-6; Ngfg; RATKALA; rGK-1; RGK-7; rK-1; RSKG-7
UniProt ID: (Human) P06870, (Rat) P00758, (Mouse) P15947, (Mouse) P00756, (Rat) P36373
Entrez Gene ID: (Human) 3816, (Rat) 24594, (Mouse) 16612, (Mouse) 18050, (Rat) 24523
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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