Product References
Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats.
Journal of veterinary science
Wang L,Lei J,Zhao Z,Jia J,Wang L
71-1500 was used in Immunohistochemistry to assess the therapeutic effects of paeoniflorin (PF) on irritable bowel syndrome in rats.
Mon May 01 00:00:00 EDT 2023
Restorative effects of Lactobacillus rhamnosus LR-32 on the gut microbiota, barrier integrity, and 5-HT metabolism in reducing feather-pecking behavior in laying hens with antibiotic-induced dysbiosis.
Frontiers in microbiology
Huang C,Yue Q,Sun L,Di K,Yang D,Hao E,Wang D,Chen Y,Shi L,Zhou R,Zhao G,Chen H
71-1500 was used in Western Blot to indicate that dietary supplementation with Lactobacillus rhamnosus LR-32 can reduce antibiotic-induced FP in laying hens and is a promising treatment to improve the welfare of domestic birds.
Wed Sep 20 00:00:00 EDT 2023
Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M).
Cells
Awad K,Barmeyer C,Bojarski C,Nagel O,Lee IM,Schweiger MR,Schulzke JD,Bücker R
71-1500 was used in Immunohistochemistry and Western Blotting to investigate the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type IBS.
Thu Jan 05 00:00:00 EST 2023
Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M).
Cells
Awad K,Barmeyer C,Bojarski C,Nagel O,Lee IM,Schweiger MR,Schulzke JD,Bücker R
71-1500 was used in Immunohistochemistry and Western Blotting to investigate the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type IBS.
Thu Jan 05 00:00:00 EST 2023
Switching from high-fat diet to normal diet ameliorate BTB integrity and improve fertility potential in obese male mice.
Scientific reports
Zhang W,Tian Z,Qi X,Chen P,Yang Q,Guan Q,Ye J,Yu C
71-1500 was used in Western Blotting to explore the effects of switching from a high-fat diet (HFD) to a normal diet (ND) on the fertility potential of obese male mice and its related mechanisms.
Tue Aug 29 00:00:00 EDT 2023
Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen.
Frontiers in cellular neuroscience
Li LY,Kreye J,Burek M,Cordero-Gomez C,Barthel PC,Sánchez-Sendín E,Kornau HC,Schmitz D,Scharf M,Meybohm P,Reincke SM,Prüss H,Höltje M
71-1500 was used in Western Blotting to conclude that autoantibodies to blood vessels occur in autoimmune encephalitis patients and might contribute to a disruption of the blood-brain barrier thereby suggesting a potential pathophysiological relevance of these antibodies.
Fri Feb 17 00:00:00 EST 2023
Macromolecule Translocation across the Intestinal Mucosa of HIV-Infected Patients by Transcytosis and through Apoptotic Leaks.
Cells
Krug SM,Grünhagen C,Allers K,Bojarski C,Seybold J,Schneider T,Schulzke JD,Epple HJ
71-1500 was used in Western Blotting to identify two pathways of increased macromolecule translocation in HIV infection: transcytosis and passage through apoptotic leaks.
Tue Jul 18 00:00:00 EDT 2023
CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia-reperfusion injury.
Experimental & molecular medicine
Zhang H,Kim H,Park BW,Noh M,Kim Y,Park J,Park JH,Kim JJ,Sim WS,Ban K,Park HJ,Kwon YG
71-1500 was used in Immunohistochemistry to investigate the role of CU06-1004 in improving cardiac function by influencing cardiac microvascular endothelial cells in ischeamia-repurfusion injury.
Sat Jan 01 00:00:00 EST 2022
Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance.
Stroke and vascular neurology
Song K,Zeng X,Xie X,Zhu R,Liang J,Chen G,Huang L
71-1500 was used in Immunohistochemistry to explore the potential mechanism of the adverse effects of cerebrovenous disorders in cerebral infarction and explore the protective effect of Dl-3-n-butylphthalide on cerebral infarction accompanied through cerebral venous disturbance.
Wed Jun 01 00:00:00 EDT 2022
Enteric nervous system modulation of luminal pH modifies the microbial environment to promote intestinal health.
PLoS pathogens
Hamilton MK,Wall ES,Robinson CD,Guillemin K,Eisen JS
71-1500 was used in Immunohistochemistry to investigated how the enteric nervous system shapes the intestinal environment in the absence of microbiota and associated inflammatory responses.
Tue Feb 01 00:00:00 EST 2022
Vascular Sema3E-Plexin-D1 Signaling Reactivation Promotes Post-stroke Recovery through VEGF Downregulation in Mice.
Translational stroke research
Yu R,Kim NS,Li Y,Jeong JY,Park SJ,Zhou B,Oh WJ
71-1500 was used in Western Blot to investigate whether Sema3E-Plexin-D1 signaling was involved in cerebrovascular remodeling after ischemic injury.
Tue Feb 01 00:00:00 EST 2022
Rifaximin enhances the L‑carnitine‑mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut‑liver‑muscle axis.
International journal of molecular medicine
Murata K,Kaji K,Nishimura N,Enomoto M,Fujimoto Y,Takeda S,Tsuji Y,Fujinaga Y,Takaya H,Kawaratani H,Namisaki T,Akahane T,Yoshiji H
71-1500 was used in Immunohistochemistry to demonstrate that the combination of rifaximin with L‚carnitine may provide a clinical benefit for liver cirrhosis‚related sarcopenia.
Mon Aug 01 00:00:00 EDT 2022
Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood-Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal Loss.
Cellular and molecular neurobiology
Chen S,Sun Y,Li F,Zhang X,Hu X,Zhao X,Li Y,Li H,Zhang J,Liu W,Zheng GQ,Jin X
71-1500 was used in Immunohistochemistry to investigate the role of melatonin in the reduction of ischemia and reperfusion (I/R)-induced blood brain barrier damage through modulation of α7nACh receptor (α7nAChR).
Sat Oct 01 00:00:00 EDT 2022
A Novel In Vitro Membrane Permeability Methodology Using Three-dimensional Caco-2 Tubules in a Microphysiological System Which Better Mimics In Vivo Physiological Conditions.
Journal of pharmaceutical sciences
Hagiwara Y,Kumagai H,Ouwerkerk N,Gijzen L,Annida R,Bokkers M,van Vught R,Yoshinari K,Katakawa Y,Motonaga K,Tajiri T
71-1500 was used in Immunohistochemistry to develop an in vitro drug permeability methodology which mimics the gastrointestinal environment more accurately than conventional 2D methodologies through 3D Caco-2 tubules using a microphysiological system.
Sat Jan 01 00:00:00 EST 2022
Astrocytic p75NTR expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Glia
Qin X,Wang J,Chen S,Liu G,Wu C,Lv Q,He X,Bai X,Huang W,Liao H
71-1500 was used in Western Blotting to provide novel insight into the role of astrocytic p75NTR in BBB disruption after acute cerebral ischemia.
Sun May 01 00:00:00 EDT 2022
Astrocytic p75NTR expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Glia
Qin X,Wang J,Chen S,Liu G,Wu C,Lv Q,He X,Bai X,Huang W,Liao H
71-1500 was used in Western Blotting to provide novel insight into the role of astrocytic p75NTR in BBB disruption after acute cerebral ischemia.
Sun May 01 00:00:00 EDT 2022
MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier.
Cells
Weiß F,Czichos C,Knobe L,Voges L,Bojarski C,Michel G,Fromm M,Krug SM
71-1500 was used in Western Blotting to conclude that the protective effects are hardly targeting the intestinal barrier directly but are based on regulatory processes supporting stabilization of the intestinal barrier.
Wed May 04 00:00:00 EDT 2022
Differential expression and localization of tight junction proteins in the goat epididymis.
Journal of animal science and technology
Kim SW,Jeong YD,Lee GY,Lee J,Lee JY,Kim CL,Ko YG,Lee SS,Kim B
71-1500 was used in Western Blot, Immunohistochemistry to suggest that the distinct expression patterns of TJ proteins are essential for regulating components of the luminal contents in the epididymal epithelium and for forming adequate luminal conditions that are necessary for the maturation, protection, transport, and storage of spermatozoa in the goat epididymis.
Sun May 01 00:00:00 EDT 2022
Differential expression and localization of tight junction proteins in the goat epididymis.
Journal of animal science and technology
Kim SW,Jeong YD,Lee GY,Lee J,Lee JY,Kim CL,Ko YG,Lee SS,Kim B
71-1500 was used in Western Blot, Immunohistochemistry to suggest that the distinct expression patterns of TJ proteins are essential for regulating components of the luminal contents in the epididymal epithelium and for forming adequate luminal conditions that are necessary for the maturation, protection, transport, and storage of spermatozoa in the goat epididymis.
Sun May 01 00:00:00 EDT 2022
Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway.
British journal of pharmacology
Wu SM,Tsai JJ,Pan HC,Arbiser JL,Elia L,Sheu ML
71-1500 was used in Western Blotting to investigate the cascade pathway involving IGF1R and AhR in idiopathic pulmonary fibrosis.
Fri Jul 01 00:00:00 EDT 2022
Busulfan impairs blood-testis barrier and spermatogenesis by increasing noncollagenous 1 domain peptide via matrix metalloproteinase 9.
Andrology
Jiang S,Xu Y,Fan Y,Hu Y,Zhang Q,Su W
71-1500 was used in Immunohistochemistry-immunofluorescence to demonstrate that elevated marix mettaloproteinase 9 and noncollagenous 1 participate in busulfan-induced blood-testis barrier disruption, which can be ameliorated by intervening with noncollagenous 1 production.
Tue Feb 01 00:00:00 EST 2022
TRPV6 channel mediates alcohol-induced gut barrier dysfunction and systemic response.
Cell reports
Meena AS,Shukla PK,Bell B,Giorgianni F,Caires R,Fernández-Peña C,Beranova S,Aihara E,Montrose MH,Chaib M,Makowski L,Neeli I,Radic MZ,Vásquez V,Jaggar JH,Cordero-Morales JF,Rao R
71-1500 was used in Immunohistochemistry-immunofluorescence to identify TRPV6, a Ca2+-permeable channel, as responsible for alcohol-induced elevation of intracellular Ca2+, intestinal barrier dysfunction, and systemic inflammation.
Tue Jun 14 00:00:00 EDT 2022
Electroacupuncture of the trigeminal nerve causes N-methyl-D-aspartate receptors to mediate blood-brain barrier opening and induces neuronal excitatory changes.
Frontiers in cellular neuroscience
Gong P,Zhang S,Ren L,Zhang J,Zhao Y,Mao X,Gan L,Wang H,Ma C,Lin Y,Ye Q,Qian K,Lin X
71-1500 was used in Western Blotting to validate that BBB permeability is promtoed by brain NMDA receptors during EA of the trigeminal nerve, as well as induction of some neuronal excitation.
Wed Nov 02 00:00:00 EDT 2022
Electroacupuncture of the trigeminal nerve causes N-methyl-D-aspartate receptors to mediate blood-brain barrier opening and induces neuronal excitatory changes.
Frontiers in cellular neuroscience
Gong P,Zhang S,Ren L,Zhang J,Zhao Y,Mao X,Gan L,Wang H,Ma C,Lin Y,Ye Q,Qian K,Lin X
71-1500 was used in Western Blotting to validate that BBB permeability is promtoed by brain NMDA receptors during EA of the trigeminal nerve, as well as induction of some neuronal excitation.
Wed Nov 02 00:00:00 EDT 2022
FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis.
Frontiers in immunology
Yang Y,Yao M,Zeng J,Zheng D,Li Q,Ni Y,Xiao X
71-1500 was used in Western Blotting to show that it is also possible for viruses to break through the BTB and enter the immunoprivileged testicular microenvironment via this mechanism.
Mon Aug 29 00:00:00 EDT 2022
WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Jaykumar AB,Plumber S,Barry DM,Binns D,Wichaidit C,Grzemska M,Earnest S,Goldsmith EJ,Cleaver O,Cobb MH
71-1500 was used in Western Blotting to demonstrate intimate connections between WNK1/OSR1 and multiple TGF-β-sensitive molecules controlling angiogenesis and suggest that WNK1 may modulate many TGF-β-regulated functions.
Tue Jul 26 00:00:00 EDT 2022
Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner.
eLife
Richards M,Nwadozi E,Pal S,Martinsson P,Kaakinen M,Gloger M,Sjöberg E,Koltowska K,Betsholtz C,Eklund L,Nordling S,Claesson-Welsh L
71-1500 was used in Western Blotting to identify structural and functional in vivo characteristics of the endothelial cell barrier.
Thu Jul 21 00:00:00 EDT 2022
Investigation of murine host sex as a biological variable in epithelial barrier function and muscle contractility in human intestinal organoids.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Beanland BT,McNeill EP,Sequeira DJ,Xue H,Shroyer NF,Speer AL
71-1500 was used in ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot to investigate intestinal organdie use for epithelial barrier function and muscle contractility modelling.
Tue Nov 01 00:00:00 EDT 2022
SARS-CoV-2-Induced Pathology-Relevance to COVID-19 Pathophysiology.
Pathophysiology : the official journal of the International Society for Pathophysiology
Zinserling VA,Semenova NY,Bikmurzina AE,Kruglova NM,Rybalchenko OV,Markov AG
71-1500 was used in Immunohistochemistry to illustrate some aspects of pathogenesis by the appropriate histopathological changes detected in observations.
Fri Jun 10 00:00:00 EDT 2022
Organotypic sinonasal airway culture systems are predictive of the mucociliary phenotype produced by bronchial airway epithelial cells.
Scientific reports
Delhove J,Alawami M,Macowan M,Lester SE,Nguyen PT,Jersmann HPA,Reynolds PN,Roscioli E
71-1500 was used in Western Blotting to apply a tissue engineering approach to generate organotypic sinonasal AEC (nAEC) epithelia to determine whether they are predictive of bronchial AEC (bAEC) models.
Thu Nov 10 00:00:00 EST 2022
A mixture of organic acids and thymol protects primary chicken intestinal epithelial cells from Clostridium perfringens infection in vitro.
Poultry science
Ghiselli F,Giovagnoni G,Felici M,Tugnoli B,Piva A,Grilli E
71-1500 was used in Immunocytochemistry to show that the usage of thymol combined with 2 organic acids can protect primary chicken intestinal epithelial cells from CP-induced damages creating a valid candidate to substitute or adjuvate the antibiotic treatment against necrotic enteritis.
Sat Oct 01 00:00:00 EDT 2022
Chicken-derived RSPO1 and WNT3 contribute to maintaining longevity of chicken intestinal organoid cultures.
Scientific reports
Oost MJ,Ijaz A,van Haarlem DA,van Summeren K,Velkers FC,Kraneveld AD,Venema K,Jansen CA,Pieters RHH,Ten Klooster JP
71-1500 was used in Immunocytochemistry-immunoflourescence to show that chicken intestinal organoids can be cultured for multiple passages using chicken-derived WNT3 and RSPO1, PGE2, and FOXO1-inhibitor.
Wed Jun 22 00:00:00 EDT 2022
Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells.
Fluids and barriers of the CNS
Walter FR,Harazin A,Tóth AE,Veszelka S,Santa-Maria AR,Barna L,Kincses A,Biczó G,Balla Z,Kui B,Maléth J,Cervenak L,Tubak V,Kittel Á,Rakonczay Z,Deli MA
71-1500 was used in Immunohistochemistry to suggest a direct effect of the cationic L-ornithine on brain endothelium. Endothelial surface glycocalyx injury was revealed both in vivo and in vitro, as an additional novel component of the BBB-related pathological changes in AP.
Thu Feb 17 00:00:00 EST 2022
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment.
Nature communications
Schneider KM,Mohs A,Gui W,Galvez EJC,Candels LS,Hoenicke L,Muthukumarasamy U,Holland CH,Elfers C,Kilic K,Schneider CV,Schierwagen R,Strnad P,Wirtz TH,Marschall HU,Latz E,Lelouvier B,Saez-Rodriguez J,de Vos W,Strowig T,Trebicka J,Trautwein C
71-1500 was used in Flow cytometry/Cell sorting to demonstrate that gut microbiota closely shapes the hepatic inflammatory microenvironment opening approaches for cancer prevention and therapy.
Fri Jul 08 00:00:00 EDT 2022
STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells.
Cellular and molecular gastroenterology and hepatology
Liang X,Xie J,Liu H,Zhao R,Zhang W,Wang H,Pan H,Zhou Y,Han W
71-1500 was used in Immunohistochemistry-immunofluorescence to establish STIM1 as a crucial regulator for the maintenance of the intestinal barrier during colitis and provide a potential target for IBD treatment.
Mon Jun 20 00:00:00 EDT 2022
STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells.
Cellular and molecular gastroenterology and hepatology
Liang X,Xie J,Liu H,Zhao R,Zhang W,Wang H,Pan H,Zhou Y,Han W
71-1500 was used in Immunohistochemistry-immunofluorescence to establish STIM1 as a crucial regulator for the maintenance of the intestinal barrier during colitis and provide a potential target for IBD treatment.
Mon Jun 20 00:00:00 EDT 2022
MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons.
Endocrinology
Tang EI,Cheng CY
71-1500 was used in Western Blot to report the function of MARK4 and another isoform MARK2 in Sertoli cells at the BTB.
Tue Oct 11 00:00:00 EDT 2022
Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine.
International journal of molecular sciences
Lanza M,Filippone A,Casili G,Giuffrè L,Scuderi SA,Paterniti I,Campolo M,Cuzzocrea S,Esposito E
71-1500 was used in Immunohistochemistry-immunofluorescence to provide corroborating evidence that SB and SP exert a protective effect on central sensitization induced by NTG through a modulation of intestinal microbiota, suggesting the potential application of SCFAs as novel supportive therapies for intestinal disfunction associated with migraine.
Wed Apr 27 00:00:00 EDT 2022
Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2.
Cell reports
Xu L,Nirwane A,Xu T,Kang M,Devasani K,Yao Y
71-1500 was used in Immunohistochemistry and Western Blotting to suggest that Col1α1+ fibroblasts repair BBB damage in ICH via the paracellular pathway in a TIMP2-dependent manner.
Tue Nov 22 00:00:00 EST 2022
Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2.
Cell reports
Xu L,Nirwane A,Xu T,Kang M,Devasani K,Yao Y
71-1500 was used in Immunohistochemistry and Western Blotting to suggest that Col1α1+ fibroblasts repair BBB damage in ICH via the paracellular pathway in a TIMP2-dependent manner.
Tue Nov 22 00:00:00 EST 2022
Apolipoprotein E genotype-dependent nutrigenetic effects to prebiotic inulin for modulating systemic metabolism and neuroprotection in mice via gut-brain axis.
Nutritional neuroscience
Yanckello LM,Hoffman JD,Chang YH,Lin P,Nehra G,Chlipala G,McCulloch SD,Hammond TC,Yackzan AT,Lane AN,Green SJ,Hartz AMS,Lin AL
71-1500 was used in Western Blotting to identify the potential nutrigenetic effects to inulin, a prebiotic fiber, in mice with different human apolipoprotein E (APOE) genetic variants.
Mon Aug 01 00:00:00 EDT 2022
Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency.
Journal of biomedical science
Tang X,Wang W,Hong G,Duan C,Zhu S,Tian Y,Han C,Qian W,Lin R,Hou X
71-1500 was used in Western Blotting to explore the mechanism of Fut2 in IBD susceptibility and to propose a new strategy for the treatment of IBD.
Mon Mar 15 00:00:00 EDT 2021
Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes.
The British journal of dermatology
El-Chami C,Foster AR,Johnson C,Clausen RP,Cornwell P,Haslam IS,Steward MC,Watson REB,Young HS,O'Neill CA
71-1500 was used in Western Blotting to characterize osmolyte transporters in skin and keratinocytes, and, using transporter inhibitors, to investigate whether osmolytes can modify tight junctions.
Mon Mar 01 00:00:00 EST 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.
Gut microbes
Marques MS,Costa AC,Osório H,Pinto ML,Relvas S,Dinis-Ribeiro M,Carneiro F,Leite M,Figueiredo C
71-1500 was used in Immunocytochemistry to propose a novel mechanism for H. pylori to disrupt epithelial integrity and functions, breaking new ground in the understanding of the pathogenesis of this highly prevalent and clinically relevant infection.
Thu Nov 18 00:00:00 EST 2021
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers.
Frontiers in oncology
Abraham HG,Ulintz PJ,Goo L,Yates JA,Little AC,Bao L,Wu Z,Merajver SD
71-1500 was used in Immunohistochemistry, Western Blot to study how RhoA- and RhoC-GTPase influence the cell-cell junctions in aggressive breast cancers.
Tue Nov 07 00:00:00 EST 2023
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers.
Frontiers in oncology
Abraham HG,Ulintz PJ,Goo L,Yates JA,Little AC,Bao L,Wu Z,Merajver SD
71-1500 was used in Immunohistochemistry, Western Blot to study how RhoA- and RhoC-GTPase influence the cell-cell junctions in aggressive breast cancers.
Tue Nov 07 00:00:00 EST 2023
N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction.
Journal of molecular medicine (Berlin, Germany)
Tawfik A,Mohamed R,Kira D,Alhusban S,Al-Shabrawey M
71-1500 was used in Western Blot to underscore a potential role for endothelial NMDAR in mediating Hcy-induced breakdown of BRB and subsequently as a potential therapeutic target in retinal diseases associated with HHcy such as DR and AMD.
Fri Jan 01 00:00:00 EST 2021
Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model.
Virulence
Wang P,Zhang J,Chen Y,Zhong H,Wang H,Li J,Zhu G,Xia P,Cui L,Li J,Dong J,Gao Q,Meng X
71-1500 was used in Immunohistochemistry to investigate the effect of colibactin in in vivo infection.
Wed Dec 01 00:00:00 EST 2021
Isolation and development of bovine primary respiratory cells as model to study influenza D virus infection.
Virology
Uprety T,Sreenivasan CC,Bhattarai S,Wang D,Kaushik RS,Li F
71-1500 was used in Immunocytochemistry-immunoflourescence to suggest that bovine primary airway epithelial cells can be utilized to model infection biology and pathophysiology of IDV and other respiratory pathogens.
Thu Jul 01 00:00:00 EDT 2021
Effects of miR‑93 on epithelial‑to‑mesenchymal transition and vasculogenic mimicry in triple‑negative breast cancer cells.
Molecular medicine reports
An G,Lu F,Huang S,Bai J,He L,Liu Y,Hou L
71-1500 was used in Western Blotting to indicate that miR‚93 depletion suppressed MDA‚MB‚231 cell viability, invasion and migration (P0.001).
Fri Jan 01 00:00:00 EST 2021
Protective Effect of the Abelmoschus manihot Flower Extract on DSS-Induced Ulcerative Colitis in Mice.
Evidence-based complementary and alternative medicine : eCAM
Wu B,Zhou Q,He Z,Wang X,Sun X,Chen Y
71-1500 was used in Enzyme-linked immunosorbent assay to confirm the therapeutic effect of Abelmoschus manihot on ulcerative colitis (UC) and explore its mechanism.
Mon Apr 25 00:00:00 EDT 2022
Research on the Protective Effect of MiR-185-3p Mediated by Huangqin-Tang Decoction (HQT) on the Epithelial Barrier Function of Ulcerative Colitis.
Evidence-based complementary and alternative medicine : eCAM
Changlin Z,Ying Z,Shuhua Z,Zeng J,Chi H
71-1500 was used in Western Blot to show that HQT treatment can alleviate the shortening of colon length and reverse the intestinal mucosal injury.
Fri Apr 29 00:00:00 EDT 2022
Standardization of esophageal adenocarcinoma in vitro model and its applicability for model drug testing.
Scientific reports
Tratnjek L,Sibinovska N,Kralj S,Makovec D,Kristan K,Kreft ME
71-1500 was used in Immunocytochemistry-immunoflourescence to characterize FLO-1 cell line under different culturing conditions with the aim of (1) examining the effect of serum-free growth medium and air-liquid interface (A-L) culturing, which better reflect physiological conditions in vivo and (2) investigating the differentiation potential of FLO-1 cells to mimic the properties of the in vivo esophageal epithelium.
Tue Mar 23 00:00:00 EDT 2021
Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture.
Scientific reports
Lian P,Braber S,Varasteh S,Wichers HJ,Folkerts G
71-1500 was used in Western Blot to investigate the effects of heat treatment and/or hypoxia on the epithelial barrier function.
Wed Jun 23 00:00:00 EDT 2021
Innate gut microbiota predisposes to high alcohol consumption.
Addiction biology
Ezquer F,Quintanilla ME,Moya-Flores F,Morales P,Munita JM,Olivares B,Landskron G,Hermoso MA,Ezquer M,Herrera-Marschitz M,Israel Y
71-1500 was used in Immunohistochemistry-immunofluorescence to indicate that the mechanisms that normally curtail heavy drinking are inhibited in alcohol-preferring animals and inform a gut microbiota origin.
Thu Jul 01 00:00:00 EDT 2021
Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis.
Cell reports
Nanou A,Bourbouli M,Vetrano S,Schaeper U,Ley S,Kollias G
71-1500 was used in Western Blot to investigate in vivo the role of Tumor progression locus 2 (Tpl2), a mitogen-activated protein kinase kinase kinase (MAP3K) member with pleiotropic effects in inflammation and cancer.
Tue May 25 00:00:00 EDT 2021
Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space.
Journal of tissue engineering and regenerative medicine
Nian S,Kearns VR,Wong DSH,Bachhuka A,Vasilev K,Williams RL,Lai WW,Lo A,Sheridan CM
71-1500 was used in Immunocytochemistry to evaluate whether the surface modification of expanded polytetrafluoroethylene (ePTFE) using an n-heptylamine (HA) plasma polymer would allow for functional epithelial monolayer formation suitable for subretinal transplant into a non-dystrophic rat model.
Fri Jan 01 00:00:00 EST 2021
Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis.
Gastroenterology
Xu J,Kausalya PJ,Van Hul N,Caldez MJ,Xu S,Ong AGM,Woo WL,Mohamed Ali S,Kaldis P,Hunziker W
71-1500 was used in Western Blotting to characterize mice with liver-specific inactivation of Tjp2.
Sat May 01 00:00:00 EDT 2021
Early alterations of neurovascular unit in the retina in mouse models of tauopathy.
Acta neuropathologica communications
Xia F,Ha Y,Shi S,Li Y,Li S,Luisi J,Kayed R,Motamedi M,Liu H,Zhang W
71-1500 was used in Immunohistochemistry-fresh tissue to suggest that retinal neurovascular unit may serve as a potential biomarker for diagnosis and staging of tauopathy as well as a platform to study molecular mechanisms of neurodegeneration.
Wed Mar 24 00:00:00 EDT 2021
The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα.
JCI insight
Bai H,Zhou R,Barravecchia M,Norman R,Friedman A,Yu D,Lin X,Young JL,Dean DA
71-1500 was used in Western Blot to elucidate a novel mechanism by which NKA regulates epithelial tight junctions and identified potential drug targets for treating ARDS and other pulmonary diseases that are caused by barrier dysfunction.
Mon Feb 22 00:00:00 EST 2021
The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα.
JCI insight
Bai H,Zhou R,Barravecchia M,Norman R,Friedman A,Yu D,Lin X,Young JL,Dean DA
71-1500 was used in Western Blot to elucidate a novel mechanism by which NKA regulates epithelial tight junctions and identified potential drug targets for treating ARDS and other pulmonary diseases that are caused by barrier dysfunction.
Mon Feb 22 00:00:00 EST 2021
Citrus limon Peel Powder Reduces Intestinal Barrier Defects and Inflammation in a Colitic Murine Experimental Model.
Foods (Basel, Switzerland)
Tinh NTT,Sitolo GC,Yamamoto Y,Suzuki T
71-1500 was used in Western Blot to examine the ameliorative effects of lemon (Citrus limon) peel (LP) powder on intestinal inflammation and barrier defects in dextran sulfate sodium (DSS)-induced colitic mice.
Mon Jan 25 00:00:00 EST 2021
Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity.
Scientific reports
Heng S,Samarajeewa N,Wang Y,Paule SG,Breen J,Nie G
71-1500 was used in Immunocytochemistry-immunofluorescence to investigate podocalyxin in embryonic implantation.
Tue Dec 14 00:00:00 EST 2021
Compromised barrier integrity of human feto-placental vessels from gestational diabetic pregnancies is related to downregulation of occludin expression.
Diabetologia
Villota SD,Toledo-Rodriguez M,Leach L
71-1500 was used in Western Blotting to investigate the effects of gestational diabetes mellitus (GDM), and its treatment, on endothelial junctional integrity, gene and protein expression of occludin splice variants, and potential regulation of expression by microRNAs (miRNAs).
Fri Jan 01 00:00:00 EST 2021
Human Astroviruses: A Tale of Two Strains.
Viruses
Hargest V,Davis AE,Tan S,Cortez V,Schultz-Cherry S
71-1500 was used in Immunocytochemistry to investigate if VA1 replicates more slowly than HAstV-1 and elicits significantly different cellular responses, including the inability to disrupt cellular junctions and barrier permeability.
Sat Feb 27 00:00:00 EST 2021
The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties.
Journal of neuroinflammation
Buzhdygan TP,Rodrigues CR,McGary HM,Khan JA,Andrews AM,Rawls SM,Ramirez SH
71-1500 was used in Western Blot to investigate the effects of the synthetic cathinone, 4-methyl methcathinone (mephedrone), on blood-brain barrier properties.
Mon Mar 01 00:00:00 EST 2021
Analysis of Cellular EMT States Using Molecular Biology and High Resolution FISH Labeling.
Methods in molecular biology (Clifton, N.J.)
Kempf N,Moutahir F,Goiffon I,Cantaloube S,Bystricky K,Lavigne AC
71-1500 was used in Western Blotting to describe methods to correlate physiological and molecular states of cells undergoing an EMT process with chromatin rearrangements observed via FISH labeling of specific domains.
Fri Mar 19 00:00:00 EDT 2021
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.
Cellular and molecular gastroenterology and hepatology
Schneider KM,Elfers C,Ghallab A,Schneider CV,Galvez EJC,Mohs A,Gui W,Candels LS,Wirtz TH,Zuehlke S,Spiteller M,Myllys M,Roulet A,Ouzerdine A,Lelouvier B,Kilic K,Liao L,Nier A,Latz E,Bergheim I,Thaiss CA,Hengstler JG,Strowig T,Trautwein C
71-1500 was used in Western Blotting to assess the association of proton pump inhibitor or long-term antibiotics intake and occurrence of acute liver failure in the 500,000 participants of the UK BioBank population-based cohort.
Mon Mar 07 00:00:00 EST 2022
Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages.
Journal of inflammation research
Wang R,Song W,Xie C,Zhong W,Xu H,Zhou Q,Deng Y,Hong Y,Li X,Fang M
71-1500 was used in Western Blot to detect zonula occludens-1 (ZO-1), occludin and claudin-5 expression in PMVECs, as well as TNF-α, TGF-β, iNOS, CD86 and CD206 expression in lungs.
Sat Apr 23 00:00:00 EDT 2022
Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages.
Journal of inflammation research
Wang R,Song W,Xie C,Zhong W,Xu H,Zhou Q,Deng Y,Hong Y,Li X,Fang M
71-1500 was used in Western Blot to detect zonula occludens-1 (ZO-1), occludin and claudin-5 expression in PMVECs, as well as TNF-α, TGF-β, iNOS, CD86 and CD206 expression in lungs.
Sat Apr 23 00:00:00 EDT 2022
Regulation of Collective Metastasis by Nanolumenal Signaling.
Cell
Wrenn ED,Yamamoto A,Moore BM,Huang Y,McBirney M,Thomas AJ,Greenwood E,Rabena YF,Rahbar H,Partridge SC,Cheung KJ
71-1500 was used in Immunocytochemistry to identify a collective signal generated by tumour cell clusters supporting metastatic colonisation.
Thu Oct 15 00:00:00 EDT 2020
Brain tight junction protein expression in sepsis in an autopsy series.
Critical care (London, England)
Erikson K,Tuominen H,Vakkala M,Liisanantti JH,Karttunen T,Syrjälä H,Ala-Kokko TI
71-1500 was used in Immunohistochemistry to investigate the expression of tight junction proteins related to endothelial permeability in brain autopsy specimens in critically ill patients deceased with sepsis and analyzed the relationship of BBB damage with measures of systemic inflammation and systemic organ dysfunction.
Mon Jun 29 00:00:00 EDT 2020
Exosome-Mediated Crosstalk between Keratinocytes and Macrophages in Cutaneous Wound Healing.
ACS nano
Zhou X,Brown BA,Siegel AP,El Masry MS,Zeng X,Song W,Das A,Khandelwal P,Clark A,Singh K,Guda PR,Gorain M,Timsina L,Xuan Y,Jacobson SC,Novotny MV,Roy S,Agarwal M,Lee RJ,Sen CK,Clemmer DE,Ghatak S
71-1500 was used in Immunohistochemistry to provide insight wherein Exoκ-GFP is recognized as a major contributor that regulates macrophage trafficking and epithelial barrier properties postinjury.
Tue Oct 27 00:00:00 EDT 2020
Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation.
Developmental cell
Cui J,Shipley FB,Shannon ML,Alturkistani O,Dani N,Webb MD,Sugden AU,Andermann ML,Lehtinen MK
71-1500 was used in Immunohistochemistry to present that the embryonic ChP forms a functional brain barrier that can mount an inflammatory response to external insults.
Mon Dec 07 00:00:00 EST 2020
Buckling of an Epithelium Growing under Spherical Confinement.
Developmental cell
Trushko A,Di Meglio I,Merzouki A,Blanch-Mercader C,Abuhattum S,Guck J,Alessandri K,Nassoy P,Kruse K,Chopard B,Roux A
71-1500 was used in Immunocytochemistry to show that forces arising from epithelial growth in three-dimensional confinement are sufficient to drive folding by buckling.
Mon Sep 14 00:00:00 EDT 2020
Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits.
Oxidative medicine and cellular longevity
Wei Z,Shen P,Cheng P,Lu Y,Wang A,Sun Z
71-1500 was used in Immunohistochemistry-immunofluorescence to investigate the appearance of obesity, insulin resistance, host inflammation, and leaky gut phenotype with or without Sennoside A in db/db mice.
Fri May 14 00:00:00 EDT 2021
The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction.
Inflammatory bowel diseases
Sayoc-Becerra A,Krishnan M,Fan S,Jimenez J,Hernandez R,Gibson K,Preciado R,Butt G,McCole DF
71-1500 was used in Western Blotting to determine if JAK inhibition by tofacitinib can rescue cytokine-induced barrier dysfunction in intestinal epithelial cells (IECs).
Tue Feb 11 00:00:00 EST 2020
Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages.
Journal of virology
Wang ZY,Zhen ZD,Fan DY,Qin CF,Han DS,Zhou HN,Wang PG,An J
71-1500 was used in Immunohistochemistry-immunofluorescence to demonstrate the protective role of Axl in antagonizing severe Japanese encephalitis (JE) and shows that the use of IL-1α antagonist may prevent severe JE.
Mon Aug 17 00:00:00 EDT 2020
The Cells and Extracellular Matrix of Human Amniotic Membrane Hinder the Growth and Invasive Potential of Bladder Urothelial Cancer Cells.
Frontiers in bioengineering and biotechnology
Ramuta TŽ,Jerman UD,Tratnjek L,Janev A,Magatti M,Vertua E,Bonassi Signoroni P,Silini AR,Parolini O,Kreft ME
71-1500 was used in Immunohistochemistry (Paraffin) to bring new knowledge on basic mechanisms of hAM affecting bladder carcinogenesis.
Fri Nov 27 00:00:00 EST 2020
Enhancement of aberrantly modified integrin‑mediated cell motility in multicellular tumor spheroids.
International journal of oncology
Kim B,Im NR,Yang TD,Kim J,Jung KY,Kim TH,Baek SK
71-1500 was used in Western Blot to conclude that the alteration of E‚cadherin expression and presence of low‚MW β1 integrin in MTS may enhance cell motility via the upregulation of EMT signaling molecules that may be intensified by blocking E‚cadherin.
Mon Jun 01 00:00:00 EDT 2020
Occludin, caveolin-1, and Alix form a multi-protein complex and regulate HIV-1 infection of brain pericytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Torices S,Roberts SA,Park M,Malhotra A,Toborek M
71-1500 was used in Western Blotting to identify a novel mechanism involved in HIV-1 infection contributing to a better understanding of the HIV-1 pathology and the associated neuroinflammatory responses.
Tue Dec 01 00:00:00 EST 2020
Phosphorylation and dephosphorylation of Ser852 and Ser889 control the clustering, localization and function of PAR3.
Journal of cell science
Yamashita K,Mizuno K,Furukawa K,Hirose H,Sakurai N,Masuda-Hirata M,Amano Y,Hirose T,Suzuki A,Ohno S
71-1500 was used in Immunocytochemistry to demonstrate that unphosphorylatable forms of PAR3 exhibited a low molecular turnover and failed to coordinate rapid reconstruction of the tight junction, supporting that both the phosphorylated and dephosphorylated states are essential for the functional integrity of PAR3.
Mon Nov 30 00:00:00 EST 2020
Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Ghezzal S,Postal BG,Quevrain E,Brot L,Seksik P,Leturque A,Thenet S,Carrière V
71-1500 was used in Simple Western - Size to show that short exposure to palm oil or palmitic acid induces intestinal dysfunctions targeting barrier integrity and inflammation.
Sat Feb 01 00:00:00 EST 2020
Lubiprostone protects esophageal mucosa from acid injury in porcine esophagus.
American journal of physiology. Gastrointestinal and liver physiology
Krüger L,Pridgen TA,Taylor ER,Garman KS,Blikslager AT
71-1500 was used in Immunohistochemistry (Paraffin) to describe the presence of anion channels ClC-2 and CFTR localized to the basal epithelia of porcine esophageal mucosa and the esophageal submucosal glands.
Wed Apr 01 00:00:00 EDT 2020
Nicotine directly affects milk production in lactating mammary epithelial cells concurrently with inactivation of STAT5 and glucocorticoid receptor in vitro.
Toxicology in vitro : an international journal published in association with BIBRA
Kobayashi K,Tsugami Y,Suzuki N,Suzuki T,Nishimura T
71-1500 was used in Western Blot to investigate whether nicotine directly affects milk production in lactating mammary epithelial cells.
Sun Mar 01 00:00:00 EST 2020
Proteomic analysis of desmosomes reveals novel components required for epidermal integrity.
Molecular biology of the cell
Badu-Nkansah KA,Lechler T
71-1500 was used in Immunohistochemistry (Frozen) to target proximity labeling approaches to further elaborate the desmosome proteome in epidermal keratinocytes.
Fri May 15 00:00:00 EDT 2020
An Intestine-on-a-Chip Model of Plug-and-Play Modularity to Study Inflammatory Processes.
SLAS technology
Gijzen L,Marescotti D,Raineri E,Nicolas A,Lanz HL,Guerrera D,van Vught R,Joore J,Vulto P,Peitsch MC,Hoeng J,Lo Sasso G,Kurek D
71-1500 was used in Immunohistochemistry to develop an immunocompetent 3D perfused intestine-on-a-chip platform for studying intestinal inflammation.
Tue Dec 01 00:00:00 EST 2020
Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton.
Experimental and therapeutic medicine
Wang H,Jiang Y,Li H,Wang J,Li C,Zhang D
71-1500 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that carbachol may protect the intestinal barrier in the severe acute pancreatitis rat model without aggravating pancreatic injury via regulation of Cdc42/F-actin expression.
Tue Sep 01 00:00:00 EDT 2020
Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton.
Experimental and therapeutic medicine
Wang H,Jiang Y,Li H,Wang J,Li C,Zhang D
71-1500 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that carbachol may protect the intestinal barrier in the severe acute pancreatitis rat model without aggravating pancreatic injury via regulation of Cdc42/F-actin expression.
Tue Sep 01 00:00:00 EDT 2020
Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease.
Biological & pharmaceutical bulletin
Onozato D,Akagawa T,Kida Y,Ogawa I,Hashita T,Iwao T,Matsunaga T
71-1500 was used in Immunocytochemistry to study the whether human induced pluripotent stem cell-derived intestinal organoids can be used as a model for inflammatory bowl disease.
Thu Dec 31 00:00:00 EST 2020
Purified IgG from aquaporin-4 neuromyelitis optica spectrum disorder patients alters blood-brain barrier permeability.
PloS one
Cobo-Calvo A,Ruiz A,Richard C,Blondel S,Cavagna S,Strazielle N,Ghersi-Egea JF,Giraudon P,Marignier R
71-1500 was used in Immunohistochemistry-immunofluorescence to evaluate the effect of human immunoglobulins from neuromyelitis optica spectrum disorders (NMOSD) patients (NMO-IgG) on blood-brain barrier (BBB) properties.
Thu Oct 22 00:00:00 EDT 2020
Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis.
PloS one
Peroutka RJ,Buzza MS,Mukhopadhyay S,Johnson TA,Driesbaugh KH,Antalis TM
71-1500 was used in Western Blot to identify testisin as a novel regulator of VE-cadherin adhesions during angiogenesis and indicate a potential new target for regulating neovascular integrity and associated pathologies.
Fri Aug 28 00:00:00 EDT 2020
Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins.
Cells
Wu CJ,Lu M,Feng X,Nakato G,Udey MC
71-1500 was used in Western Blotting to reveal that TROP2 is also a matriptase substrate.
Tue Apr 21 00:00:00 EDT 2020
Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome.
Biomedicines
Scuderi SA,Casili G,Lanza M,Filippone A,Paterniti I,Esposito E,Campolo M
71-1500 was used in Immunohistochemistry to demonstrate that IBS-D induced NLRP3 inflammasome pathway activation, accompanied by the production of proinflammatory response.
Fri Nov 20 00:00:00 EST 2020
Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator-induced brain damage following cerebral ischemia.
Journal of neurochemistry
Halder SK,Matsunaga H,Ueda H
71-1500 was used in Western Blotting to examine the beneficial effects of ProTα or P6Q against delayed tPA-induced brain damage following middle cerebral artery occlusion (MCAO) or photochemically induced thrombosis in mice.
Mon Jun 01 00:00:00 EDT 2020
Principal component analysis, a useful tool to study cyclin-dependent kinase-inhibitor's effect on cerebral ischaemia.
Brain communications
Le Roy L,Amara A,Le Roux C,Bocher O,Létondor A,Benz N,Timsit S
71-1500 was used in Western Blotting to study the mechanisms implicated in the anti-oedematous effect of (S)-roscovitine in a transient middle cerebral artery occlusion rat model 48 h after reperfusion.
Fri Mar 29 00:00:00 EDT 2024
Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity.
Fluids and barriers of the CNS
Aoki H,Yamashita M,Hashita T,Iwao T,Matsunaga T
71-1500 was used in Immunocytochemistry-immunoflourescence to show that the LN221F-iBMELCs had more robust barrier function for a longer period than Matrigel-iBMELCs with characteristics of BMECs.
Mon Mar 30 00:00:00 EDT 2020
Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity.
Fluids and barriers of the CNS
Aoki H,Yamashita M,Hashita T,Iwao T,Matsunaga T
71-1500 was used in Immunocytochemistry-immunoflourescence to show that the LN221F-iBMELCs had more robust barrier function for a longer period than Matrigel-iBMELCs with characteristics of BMECs.
Mon Mar 30 00:00:00 EDT 2020
Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model.
International journal of molecular sciences
Filippone A,Consoli GML,Granata G,Casili G,Lanza M,Ardizzone A,Cuzzocrea S,Esposito E,Paterniti I
71-1500 was used in Immunohistochemistry to investigate the therapeutic efficacy of a nanohydrogel drug delivery system in treating psoriasis.
Fri Jul 17 00:00:00 EDT 2020
AhR activation defends gut barrier integrity against damage occurring in obesity.
Molecular metabolism
Postal BG,Ghezzal S,Aguanno D,André S,Garbin K,Genser L,Brot-Laroche E,Poitou C,Soula H,Leturque A,Clément K,Carrière V
71-1500 was used in Immunocytochemistry to study the causal relationship between AhR activation and gut inflammation in obesity.
Tue Sep 01 00:00:00 EDT 2020
AhR activation defends gut barrier integrity against damage occurring in obesity.
Molecular metabolism
Postal BG,Ghezzal S,Aguanno D,André S,Garbin K,Genser L,Brot-Laroche E,Poitou C,Soula H,Leturque A,Clément K,Carrière V
71-1500 was used in Immunocytochemistry to study the causal relationship between AhR activation and gut inflammation in obesity.
Tue Sep 01 00:00:00 EDT 2020
Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro.
International journal of molecular sciences
Marcu IC,Eberhard N,Yerly A,Balmer V,Hemphill A,Mogel H,Gaschen V,Stoffel MH,Bluteau J
71-1500 was used in Immunohistochemistry to report on the intracellular uptake of fluorescently labelled human urine and fibroblast-derived small EVs by human RPE cells.
Wed May 27 00:00:00 EDT 2020
Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance.
Scientific reports
Roudnicky F,Kim BK,Lan Y,Schmucki R,Küppers V,Christensen K,Graf M,Patsch C,Burcin M,Meyer CA,Westenskow PD,Cowan CA
71-1500 was used in Immunocytochemistry to predict TFs that induce high-resistance barrier properties of ECs as in the BBB.
Tue Mar 03 00:00:00 EST 2020
Temporal pressure enhanced topical drug delivery through micropore formation.
Science advances
Lio DCS,Chia RN,Kwek MSY,Wiraja C,Madden LE,Chang H,Khadir SMA,Wang X,Becker DL,Xu C
71-1500 was used in Immunohistochemistry (Paraffin) to enhance the penetration of drugs based on temporal pressure to create micropores on the epidermal layer.
Fri May 01 00:00:00 EDT 2020
Specific Frequency Electroacupuncture Stimulation Transiently Enhances the Permeability of the Blood-Brain Barrier and Induces Tight Junction Changes.
Frontiers in neuroscience
Zhang S,Gong P,Zhang J,Mao X,Zhao Y,Wang H,Gan L,Lin X
71-1500 was used in Western Blot, Immunohistochemistry to propose that specific frequency EA can transiently open the BBB and may be related to the change of tight junctions (TJ).
Sat Oct 31 00:00:00 EDT 2020
Specific Frequency Electroacupuncture Stimulation Transiently Enhances the Permeability of the Blood-Brain Barrier and Induces Tight Junction Changes.
Frontiers in neuroscience
Zhang S,Gong P,Zhang J,Mao X,Zhao Y,Wang H,Gan L,Lin X
71-1500 was used in Western Blot, Immunohistochemistry to propose that specific frequency EA can transiently open the BBB and may be related to the change of tight junctions (TJ).
Sat Oct 31 00:00:00 EDT 2020
Impaired Airway Epithelial Barrier Integrity in Response to Stenotrophomonas maltophilia Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics.
Frontiers in immunology
Molloy K,Cagney G,Dillon ET,Wynne K,Greene CM,McElvaney NG
71-1500 was used in Western Blot to demonstrate destruction of the CFBE41o- TJC provide a novel insight regarding the virulence of S. maltophilia and may explain the possible injurious effects of this bacterium on the CF bronchial epithelium and the pathogenic mechanism leading to lethal pulmonary hemorrhage.
Fri Feb 19 00:00:00 EST 2021
Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
International journal of molecular sciences
Kjærgaard S,Damm MMB,Chang J,Riis LB,Rasmussen HB,Hytting-Andreasen R,Krug SM,Schulzke JD,Bindslev N,Hansen MB
71-1500 was used in Western Blot to study mucosal healing on a molecular and functional level in quiescent ulcerative colitis (UC).
Tue Mar 10 00:00:00 EDT 2020
Leptin protects brain from ischemia/reperfusion-induced infarction by stabilizing the blood-brain barrier to block brain infiltration by the blood-borne neutrophils.
The European journal of neuroscience
Hung WT,Wang CH,Lin SY,Cheng SY,Liao LY,Lu LY,Chen YJ,Huang YZ,Lin CH,Hsueh CM
71-1500 was used in Western Blotting to demonstrate that leptin could protect ischemic brain via multiple ways (other than neuronal protection), by inhibiting the BBB permeability, brain infiltration of the blood-borne neutrophils and neutrophil adherence to vascular ECs.
Tue Dec 01 00:00:00 EST 2020
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
Frontiers in pharmacology
He S,Guo Y,Zhao J,Xu X,Wang N,Liu Q
71-1500 was used in Western Blotting to uncover the protective effect of ferulic acid (FA) on intestinal epithelial barrier dysfunction in a Caco-2 cell model of lipopolysaccharide (LPS) stimulation and the underlying mechanism.
Mon Sep 28 00:00:00 EDT 2020
Long-term lutein administration attenuates retinal inflammation and functional deficits in early diabetic retinopathy using the Ins2Akita/+ mice.
BMJ open diabetes research & care
Wang W,Tam KC,Ng TC,Goit RK,Chan KLS,Lo ACY
71-1500 was used in Western Blotting to demonstrate lutein's potential as a long-term therapeutic intervention for prevention of inflammation and retinal degeneration in patients with early diabetic retinopathy.
Wed Jul 01 00:00:00 EDT 2020
The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption.
Tissue barriers
Aguanno D,Coquant G,Postal BG,Osinski C,Wieckowski M,Stockholm D,Grill JP,Carrière V,Seksik P,Thenet S
71-1500 was used in Immunocytochemistry-immunoflourescence to identify new actors involved in host-microbiota interplay in IBD, and study N-acyl homoserine lactones (AHL), molecules of the bacterial quorum sensing, which also impact the host.
Thu Oct 01 00:00:00 EDT 2020
Testin regulates the blood-testis barrier via disturbing occludin/ZO-1 association and actin organization.
Journal of cellular physiology
Su L,Wang Z,Xie S,Hu D,Cheng YC,Mruk DD,Guan Y
71-1500 was used in Western Blotting to suggest that besides as a monitor for Sertoli-germ cell junction integrity, testin is also an essential molecule to maintain Sertoli-Sertoli junctions.
Tue Sep 01 00:00:00 EDT 2020
Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation.
Cellular and molecular gastroenterology and hepatology
Xing T,Benderman LJ,Sabu S,Parker J,Yang J,Lu Q,Ding L,Chen YH
71-1500 was used in Western Blotting to show that Cldn7 is indispensable in controlling Wnt/β-catenin signaling-dependent intestinal epithelial stem cell survival, self-renewal, and cell differentiation.
Mon May 10 00:00:00 EDT 2021
Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles.
Scientific reports
Rom S,Heldt NA,Gajghate S,Seliga A,Reichenbach NL,Persidsky Y
71-1500 was used in Immunocytochemistry to demonstrate that exposure of brain microvessels to hyperglycemic conditions or advanced glycation end products (AGEs) ex vivo results in significant abnormalities in membranous distribution of TJ proteins.
Wed Apr 29 00:00:00 EDT 2020
Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.
Poultry science
Pardyak L,Kaminska A,Brzoskwinia M,Hejmej A,Kotula-Balak M,Jankowski J,Ciereszko A,Bilinska B
71-1500 was used in Immunohistochemistry (Paraffin) to provide new information on the localization and expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys, and compare expression of junctional protein genes between 2 turkey population, one that produces white normal semen (WNS) and the other that produces yellow abnormal semen.
Wed Jan 01 00:00:00 EST 2020
The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples.
Acta neuropathologica communications
Duarte Lobo D,Nobre RJ,Oliveira Miranda C,Pereira D,Castelhano J,Sereno J,Koeppen A,Castelo-Branco M,Pereira de Almeida L
71-1500 was used in Western Blotting to demonstrate that blood-brain barrier (BBB) impairment in Machado-Joseph disease/SCA type 3 (MJD/SCA3).
Mon Aug 31 00:00:00 EDT 2020
Self-assembling vascular endothelial growth factor nanoparticles improve function in spinocerebellar ataxia type 1.
Brain : a journal of neurology
Hu YS,Do J,Edamakanti CR,Kini AR,Martina M,Stupp SI,Opal P
71-1500 was used in Western Blotting to test a synthetic VEGF peptide amphiphile that self-assembles into nanoparticles.
Fri Feb 01 00:00:00 EST 2019
In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier.
Environment international
Luo S,Terciolo C,Bracarense APFL,Payros D,Pinton P,Oswald IP
71-1500 was used in Western Blot to evaluate the combined toxicicty of deoxynivalenol and cadmium on the intestinal barrier function in vitro and in vivo.
Fri Nov 01 00:00:00 EDT 2019
Tubulin detyrosination promotes human trophoblast syncytium formation.
Journal of molecular cell biology
Wang R,Yu R,Zhu C,Lin HY,Lu X,Wang H
71-1500 was used in Western Blot to show that tubulin detyrosination plays an essential role in human trophoblast fusogenic protein aggregation and syncytialisation.
Mon Dec 23 00:00:00 EST 2019
Metformin Improves Fertility in Obese Males by Alleviating Oxidative Stress-Induced Blood-Testis Barrier Damage.
Oxidative medicine and cellular longevity
Ye J,Luo D,Xu X,Sun M,Su X,Tian Z,Zhang M,Yu C,Guan Q
71-1500 was used in Western Blotting to explore the effects of metformin and characterising its underlying mechanism in the fertility of obese males.
Fri Mar 20 00:00:00 EDT 2020
Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood-brain barrier permeability in the corpus callosum.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Liu Q,Radwanski R,Babadjouni R,Patel A,Hodis DM,Baumbacher P,Zhao Z,Zlokovic B,Mack WJ
71-1500 was used in Immunohistochemistry to characterize the time course of BBB dysfunction and pericyte coverage following murine experimental CCH secondary to bilateral carotid artery stenosis (BCAS).
Fri Feb 01 00:00:00 EST 2019
Linear and circular CDKN2B-AS1 expression is associated with Inflammatory Bowel Disease and participates in intestinal barrier formation.
Life sciences
Rankin CR,Lokhandwala ZA,Huang R,Pekow J,Pothoulakis C,Padua D
71-1500 was used in Immunocytochemistry to characterize one specific lncRNA, CDKN2B-AS1 whose expression was downregulated in UC patients. UC biopsies were used to determine the levels of linear and circular CDKN2B-AS1 relative to healthy controls. Additonally, an RT-PCR array, immunoblots and immunohistochemistry were used to determine tight junction proteins that CDKN2B-AS1 regulates.
Thu Aug 15 00:00:00 EDT 2019
mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model.
American journal of physiology. Endocrinology and metabolism
Yan M,Li L,Mao B,Li H,Li SYT,Mruk D,Silvestrini B,Lian Q,Ge R,Cheng CY
71-1500 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that combining overexpression of p-rpS6-MT with a male contraceptive (e.g., adjudin) potentiate the drug bioavailability by modifying the blood-testis barrier.
Mon Jul 01 00:00:00 EDT 2019
mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model.
American journal of physiology. Endocrinology and metabolism
Yan M,Li L,Mao B,Li H,Li SYT,Mruk D,Silvestrini B,Lian Q,Ge R,Cheng CY
71-1500 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that combining overexpression of p-rpS6-MT with a male contraceptive (e.g., adjudin) potentiate the drug bioavailability by modifying the blood-testis barrier.
Mon Jul 01 00:00:00 EDT 2019
Changes in brain kynurenine levels via gut microbiota and gut-barrier disruption induced by chronic ethanol exposure in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Giménez-Gómez P,Pérez-Hernández M,O'Shea E,Caso JR,Martín-Hernandez D,Cervera LA,Centelles MLG,Gutiérrez-Lopez MD,Colado MI
71-1500 was used in Western Blotting to study Ethanol (EtOH) exposure effects on Trp metabolism and the involvement of gut microbiota.
Fri Nov 01 00:00:00 EDT 2019
Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4.
Molecular neurobiology
Abdul Y,Abdelsaid M,Li W,Webb RC,Sullivan JC,Dong G,Ergul A
71-1500 was used in Western Blotting to explore whether inhibition of TLR-4 signaling prevents endothelial cell death and improves outcomes after stroke.
Fri Mar 01 00:00:00 EST 2019
Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages.
Oncology reports
An G,Wu F,Huang S,Feng L,Bai J,Gu S,Zhao X
71-1500 was used in Western Blotting to demonstrate that the positive expression of C-C motif chemokine ligand 5 was associated with lymph node status and tumour-node-metastasis stage.
Sun Dec 01 00:00:00 EST 2019
One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats.
Nutritional neuroscience
Rijnsburger M,Unmehopa UA,Eggels L,Serlie MJ,la Fleur SE
71-1500 was used in Western Blot to investigate the effect of a high fat high sugar diet on the blood brain barrier permeability.
Thu Aug 01 00:00:00 EDT 2019
Gut epithelial and vascular barrier abnormalities in patients with chronic intestinal pseudo-obstruction.
Neurogastroenterology and motility
Boschetti E,Accarino A,Malagelada C,Malagelada JR,Cogliandro RF,Gori A,Tugnoli V,Giancola F,Bianco F,Bonora E,Clavenzani P,Volta U,Caio G,Sternini C,Stanghellini V,Azpiroz F,De Giorgio R
71-1500 was used in Western Blotting to provide support to IEVB abnormalities contributing to CIPO clinical and histopathological features.
Thu Aug 01 00:00:00 EDT 2019
Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
He S,Guo Y,Zhao J,Xu X,Song J,Wang N,Liu Q
71-1500 was used in Western Blotting to study the role of ferulic acid in protection of IEC-6 cells from heat stress-induced intestinal epithelial barrier dysfunction.
Tue Jan 01 00:00:00 EST 2019
GPR55-mediated effects on brain microvascular endothelial cells and the blood-brain barrier.
Neuroscience
Leo LM,Familusi B,Hoang M,Smith R,Lindenau K,Sporici KT,Brailoiu E,Abood ME,Brailoiu GC
71-1500 was used in Immunocytochemistry to examine the effect of GPR55 activation on rat brain microvascular endothelial cells, an essential component of the blood-brain barrier. GPR55 was detected by western blot and immunocytochemistry.
Wed Aug 21 00:00:00 EDT 2019
Muc5b-deficient mice develop early histological lung abnormalities.
Biology open
Valque H,Gouyer V,Duez C,Leboeuf C,Marquillies P,Le Bert M,Plet S,Ryffel B,Janin A,Gottrand F,Desseyn JL
71-1500 was used in Immunohistochemistry to demonstrate that Muc5b is essential for maintaining normal lung function.
Thu Nov 07 00:00:00 EST 2019
Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis.
Redox biology
Cremonini E,Daveri E,Mastaloudis A,Adamo AM,Mills D,Kalanetra K,Hester SN,Wood SM,Fraga CG,Oteiza PI
71-1500 was used in Western Blotting to investigate if benefits of previous supplementation is related to anthocyanins capacity to sustain intestinal monolayer integrity and HFD-associated dysbiosis.
Sun Sep 01 00:00:00 EDT 2019
HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice.
Journal of neuroinflammation
Zhao Q,Zhang F,Yu Z,Guo S,Liu N,Jiang Y,Lo EH,Xu Y,Wang X
71-1500 was used in Western Blotting to study the role of histone deacetylase 3 in type 2 diabetes mellitus.
Fri May 17 00:00:00 EDT 2019
HDAC3 inhibition prevents oxygen glucose deprivation/reoxygenation-induced transendothelial permeability by elevating PPARγ activity in vitro.
Journal of neurochemistry
Zhao Q,Yu Z,Zhang F,Huang L,Xing C,Liu N,Xu Y,Wang X
71-1500 was used in Western Blotting to indicate that HDAC3 inhibition might comprise a new therapeutic target for reducing blood-brain barrier integrity disruption and vascular dysfunctions in neurological disorders.
Mon Apr 01 00:00:00 EDT 2019
Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H2O2-Induced Oxidative Damage.
Antioxidants (Basel, Switzerland)
Yang R,Hui Q,Jiang Q,Liu S,Zhang H,Wu J,Lin F,O K,Yang C
71-1500 was used in Western Blotting to investigate the antioxidant effects of red-osier dogwood extracts (RDE) on an oxidative damage model of Caco-2 cells.
Sun Jul 28 00:00:00 EDT 2019
A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function.
Scientific reports
Alvarez R,Stork CA,Sayoc-Becerra A,Marchelletta RR,Prisk GK,McCole DF
71-1500 was used in Western Blotting to identify if simulated microgravity alters intestinal epithelial barrier function (permeability), and susceptibility to barrier disrupting agents.
Tue Nov 26 00:00:00 EST 2019
Claudin-12 is not required for blood-brain barrier tight junction function.
Fluids and barriers of the CNS
Castro Dias M,Coisne C,Baden P,Enzmann G,Garrett L,Becker L,Hölter SM,Hrabě de Angelis M,Deutsch U,Engelhardt B
71-1500 was used in Western Blotting to study the role and localisation of claudin-12.
Thu Sep 12 00:00:00 EDT 2019
Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke.
Scientific reports
Salas-Perdomo A,Miró-Mur F,Gallizioli M,Brait VH,Justicia C,Meissner A,Urra X,Chamorro A,Planas AM
71-1500 was used in Western Blotting to study changes in sphingosine-1-phosphate-signalling in response to brain ischemia/reperfusion.
Wed Jun 05 00:00:00 EDT 2019
The 12-HHT/BLT2/NO Axis Is Associated to the Wound Healing and Skin Condition in Different Glycaemic States.
Medical sciences (Basel, Switzerland)
Leguina-Ruzzi A,Ortiz Diban R,Velarde V
71-1500 was used in Western Blotting to study the assocaition between the 12-HHT/BLT2 axis and the nitric oxide production in wound healing under different glycaemia conditions.
Wed Apr 24 00:00:00 EDT 2019
Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Su W,Cheng CY
71-1500 was used in Immunocytochemistry to show that this NC1 peptide regulates testis function by inducing Sertoli cell blood-testis barrier (BTB) remodeling and is also capable of inducing elongate spermatid exfoliation through its disruptive effects on the organization of actin- and microtubule (MT)-based cytoskeletons at these cell adhesion sites.
Sun Dec 01 00:00:00 EST 2019
Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Su W,Cheng CY
71-1500 was used in Immunocytochemistry to show that this NC1 peptide regulates testis function by inducing Sertoli cell blood-testis barrier (BTB) remodeling and is also capable of inducing elongate spermatid exfoliation through its disruptive effects on the organization of actin- and microtubule (MT)-based cytoskeletons at these cell adhesion sites.
Sun Dec 01 00:00:00 EST 2019
Japanese encephalitis virus neuropenetrance is driven by mast cell chymase.
Nature communications
Hsieh JT,Rathore APS,Soundarajan G,St John AL
71-1500 was used in Western Blotting to study the mechanisms of Japanese encephalitis at the blood brain barrier.
Mon Feb 11 00:00:00 EST 2019
Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability.
Cells
Miranda J,Martín-Tapia D,Valdespino-Vázquez Y,Alarcón L,Espejel-Nuñez A,Guzmán-Huerta M,Muñoz-Medina JE,Shibayama M,Chávez-Munguía B,Estrada-Gutiérrez G,Lievano S,Ludert JE,González-Mariscal L
71-1500 was used in Western Blotting to determine whether ZIKV can open the paracellular pathway of STB cells which have been seen to be resistant to ZIKV infections.
Sun Sep 29 00:00:00 EDT 2019
Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells.
Toxins
Mehdizadeh Gohari I,Li J,Navarro M,Uzal F,McClane B
71-1500 was used in Western Blotting to show that CLDN-1 positively and negatively influences Clostridium perfringens enterotoxin (CPE) action.
Wed Oct 09 00:00:00 EDT 2019
Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability.
PloS one
Rivera J,Isidro RA,Loucil-Alicea RY,Cruz ML,Appleyard CB,Isidro AA,Chompre G,Colon-Rivera K,Noel RJ
71-1500 was used in Immunohistochemistry-immunofluorescence to suggest that Nef contributes to the chronic inflammation seen in HIV patients, even in those whose viremia is controlled by cART.
Wed Mar 25 00:00:00 EDT 2020
Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy.
Frontiers in cellular neuroscience
Smith NA,Germundson DL,Combs CK,Vendsel LP,Nagamoto-Combs K
71-1500 was used in Immunohistochemistry to demonstrate that beta-lactoglobulin sensitisation elicits inflammatory responses in the intestine and brain without overt anaphylactic signs of milk allergy.
Thu Oct 01 00:00:00 EDT 2020
FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction.
The Journal of clinical investigation
Zhou SY,Gillilland M,Wu X,Leelasinjaroen P,Zhang G,Zhou H,Ye B,Lu Y,Owyang C
71-1500 was used in Western Blotting to demonstrate how a high FODMAP diet leads to high levels of fecal lipopolysaccharides, gut dysbiosis and visceral hypersensitivity, and propose a low FODMAP diet as beneficial to IBS patients.
Tue Jan 02 00:00:00 EST 2018
Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy.
Brain, behavior, and immunity
Clayton AM,Shao Q,Paauw ND,Giambrone AB,Granger JP,Warrington JP
71-1500 was used in Western Blotting to suggest that 2 months postpartum, neuroinflammation, along with decreased occludin expression, may partly explain posterior cortical edema in rats with history of placental ischemia.
Tue May 01 00:00:00 EDT 2018
Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes.
The Journal of pathology
Genser L,Aguanno D,Soula HA,Dong L,Trystram L,Assmann K,Salem JE,Vaillant JC,Oppert JM,Laugerette F,Michalski MC,Wind P,Rousset M,Brot-Laroche E,Leturque A,Clément K,Thenet S,Poitou C
71-1500 was used in Simple Western - Size to investigate whether intestinal permeability is altered in human obesity.
Mon Oct 01 00:00:00 EDT 2018
β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Izawa Y,Gu YH,Osada T,Kanazawa M,Hawkins BT,Koziol JA,Papayannopoulou T,Spatz M,Del Zoppo GJ
71-1500 was used in Immunohistochemistry-immunofluorescence to study how interruptions to β1-integrin-matrix adhesion lead to increased permeability in the the blood-brain barrier.
Sun Apr 01 00:00:00 EDT 2018
Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain.
The Journal of physiology
Ved N,Da Vitoria Lobo ME,Bestall SM,L Vidueira C,Beazley-Long N,Ballmer-Hofer K,Hirashima M,Bates DO,Donaldson LF,Hulse RP
71-1500 was used in Western Blotting to indicate that hyperglycaemia leads to a reduction in the VEGF-A/VEGFR2 signalling cascade, resulting in endothelial dysfunction in the spinal cord, which could be an undiscovered contributing factor to diabetic neuropathic pain.
Wed Aug 01 00:00:00 EDT 2018
Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis.
American journal of physiology. Endocrinology and metabolism
Wen Q,Tang EI,Lui WY,Lee WM,Wong CKC,Silvestrini B,Cheng CY
71-1500 was used in Western Blotting to investigate the role of dynein 1 in supporting the transport of spermatids and organelles across the seminiferous epithelium during spermatogenesis.
Thu Nov 01 00:00:00 EDT 2018
Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells.
Drug metabolism and disposition: the biological fate of chemicals
Onozato D,Yamashita M,Nakanishi A,Akagawa T,Kida Y,Ogawa I,Hashita T,Iwao T,Matsunaga T
71-1500 was used in Immunohistochemistry-immunofluorescence to demonstrate the successful generation of pharmacokinetically functional intestinal organoids from human iPS cells.
Thu Nov 01 00:00:00 EDT 2018
Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells.
Frontiers in microbiology
Marques MS,Melo J,Cavadas B,Mendes N,Pereira L,Carneiro F,Figueiredo C,Leite M
71-1500 was used in Western Blotting to show that Afadin is downregulated by H. pylori infection in vitro and in vivo and its downregulated leads to the emergence of epithelial-to-mesenchymal transition, which can contribute to gastric carcinogenesis.
Thu Oct 01 00:00:00 EDT 2020
Probiotic Lactobacillus paracasei A221 improves the functionality and bioavailability of kaempferol-glucoside in kale by its glucosidase activity.
Scientific reports
Shimojo Y,Ozawa Y,Toda T,Igami K,Shimizu T
71-1500 was used in Immunocytochemistry to show the enhancing effect Lactobacillus paracasei A221 has on the anti-aging properties of kaempferol-glucosides found in kale.
Mon Jun 18 00:00:00 EDT 2018
Expression patterns of tight junction proteins in porcine major salivary glands: a comparison study with human and murine glands.
Journal of anatomy
Zhang XM,Huang Y,Zhang K,Qu LH,Cong X,Su JZ,Wu LL,Yu GY,Zhang Y
71-1500 was used in Immunohistochemistry-immunofluorescence to show that porcine parotid glands were pure serous glands and show the expression pattern of TJ proteins in salivary glands is similar between human and miniature pig, which may be a candidate animal for studies on salivary gland TJ function.
Wed Aug 01 00:00:00 EDT 2018
Expression patterns of tight junction proteins in porcine major salivary glands: a comparison study with human and murine glands.
Journal of anatomy
Zhang XM,Huang Y,Zhang K,Qu LH,Cong X,Su JZ,Wu LL,Yu GY,Zhang Y
71-1500 was used in Immunohistochemistry-immunofluorescence to show that porcine parotid glands were pure serous glands and show the expression pattern of TJ proteins in salivary glands is similar between human and miniature pig, which may be a candidate animal for studies on salivary gland TJ function.
Wed Aug 01 00:00:00 EDT 2018
Expression patterns of tight junction proteins in porcine major salivary glands: a comparison study with human and murine glands.
Journal of anatomy
Zhang XM,Huang Y,Zhang K,Qu LH,Cong X,Su JZ,Wu LL,Yu GY,Zhang Y
71-1500 was used in Immunohistochemistry-immunofluorescence to show that porcine parotid glands were pure serous glands and show the expression pattern of TJ proteins in salivary glands is similar between human and miniature pig, which may be a candidate animal for studies on salivary gland TJ function.
Wed Aug 01 00:00:00 EDT 2018
Mechanical load increase-induced changes in cytoskeletal structure and cellular barrier function in human cerebral endothelial cells.
Biotechnology and bioengineering
Kim D,Kwon S
71-1500 was used in Immunocytochemistry-immunofluorescence to indicate that increased mechanical load due to the applied hypergravity affects the cytoskeletal arrangement and tight junctions, thereby weakening the cell barrier function and enhancing the permeability of the paracellular pathway.
Mon Oct 01 00:00:00 EDT 2018
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Cell research
Xu B,Zhang Y,Du XF,Li J,Zi HX,Bu JW,Yan Y,Han H,Du JL
71-1500 was used in Western Blotting to indicate that miR-132 acts as an intercellular signal mediating neural regulation of the brain vascular integrity.
Sat Jul 01 00:00:00 EDT 2017
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Gut
Rolland-Fourcade C,Denadai-Souza A,Cirillo C,Lopez C,Jaramillo JO,Desormeaux C,Cenac N,Motta JP,Larauche M,Taché Y,Vanden Berghe P,Neunlist M,Coron E,Kirzin S,Portier G,Bonnet D,Alric L,Vanner S,Deraison C,Vergnolle N
71-1500 was used in Immunocytochemistry-immunoflourescence to show visceral hypersensitivity is induced by active protease trypsin 3 which is produced and released by the intestinal epithelium in irritable bowel syndrome.
Sun Oct 01 00:00:00 EDT 2017
Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice.
Brain, behavior, and immunity
de Sousa Rodrigues ME,Bekhbat M,Houser MC,Chang J,Walker DI,Jones DP,Oller do Nascimento CMP,Barnum CJ,Tansey MG
711500 was used in immunohistochemistry and western blot to explore the effects of mild chronic psychological stress on metabolic, inflammatory, and behavioral profiles in a mouse model of diet-induced obesity
Sun Jan 01 00:00:00 EST 2017
Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions.
Annals of the New York Academy of Sciences
Vasileva E,Sluysmans S,Bochaton-Piallat ML,Citi S
71-1500 was used in Western Blotting to determine how the molecular organization of junctions is tuned to the widely diverse physiological requirements of each tissue type.
Sun Oct 01 00:00:00 EDT 2017
Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions.
Annals of the New York Academy of Sciences
Vasileva E,Sluysmans S,Bochaton-Piallat ML,Citi S
71-1500 was used in Western Blotting to determine how the molecular organization of junctions is tuned to the widely diverse physiological requirements of each tissue type.
Sun Oct 01 00:00:00 EDT 2017
Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions.
Annals of the New York Academy of Sciences
Vasileva E,Sluysmans S,Bochaton-Piallat ML,Citi S
71-1500 was used in Western Blotting to determine how the molecular organization of junctions is tuned to the widely diverse physiological requirements of each tissue type.
Sun Oct 01 00:00:00 EDT 2017
Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen H,Mruk DD,Lee WM,Cheng CY
71-1500 was used in Western Blotting to report that NC1 domain derived from collagen α3(IV) chain-a major structural component of the BM-was capable of inducing BTB remodeling.
Tue Aug 01 00:00:00 EDT 2017
Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology.
Journal of molecular medicine (Berlin, Germany)
Obert E,Strauss R,Brandon C,Grek C,Ghatnekar G,Gourdie R,Rohrer B
71-1500 was used in Immunohistochemistry-immunofluorescence to study the effect of zonula-occludens-1 on maintenance of blood-retina barrier integrity and reduction of retinal pigment epithelium pathophysiology.
Mon May 01 00:00:00 EDT 2017
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry.
Journal of materials science. Materials in medicine
Kearns VR,Tasker J,Akhtar R,Bachhuka A,Vasilev K,Sheridan CM,Williams RL
71-1500 was used in Immunocytochemistry to determine whether a functioning monolayer of retinal pigment epithelial cells could be produced on expanded polytetrafluoroethylene substrates modified by either an ammonia plasma treatment of an n-Heptylamine coating.
Tue Aug 01 00:00:00 EDT 2017
In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome.
Molecular human reproduction
Di Pietro M,Pascuali N,Scotti L,Irusta G,Bas D,May M,Tesone M,Abramovich D,Parborell F
71-1500 was used in Western Blotting to show that in vivo administration of S1P may prevent the early onset of ovarian hyperstimulation syndrome (OHSS) and decrease its severity.
Thu Jun 01 00:00:00 EDT 2017
Stenotrophomonas maltophilia Serine Protease StmPr1 Induces Matrilysis, Anoikis, and Protease-Activated Receptor 2 Activation in Human Lung Epithelial Cells.
Infection and immunity
DuMont AL,Cianciotto NP
71-1500 was used in Western Blotting to show that the degradative and cytotoxic activities exhibited by serine protease, StmPr1, may contribute to S. maltophilia pathogenesis in the lung.
Fri Dec 01 00:00:00 EST 2017
Establishment and evaluation of an experimental rat model for high-altitude intestinal barrier injury.
Experimental and therapeutic medicine
Luo H,Zhou DJ,Chen Z,Zhou QQ,Wu K,Tian K,Li ZW,Xiao ZL
71-1500 was used in Western Blotting to study the pathogenesis, prevention and treatment of altitude sickness.
Wed Feb 01 00:00:00 EST 2017
MDCK cells are capable of water secretion and reabsorption in response to changes in the ionic environment.
Canadian journal of physiology and pharmacology
Capra JP,Eskelinen SM
711500 was used in immunocytochemistry to assess changes in the cell and luminal volumes of type II Madin-Darby canine kidney cells grown in response to drugs or to changes in the composition of the basal extracellular fluid
Sun Jan 01 00:00:00 EST 2017
Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury.
Translational research : the journal of laboratory and clinical medicine
Chehaibi K,le Maire L,Bradoni S,Escola JC,Blanco-Vaca F,Slimane MN
711500 was used in western blot to report the effects of peroxisome proliferator-activated receptor beta/delta agonist on the acute phase response after brain injury
Sat Apr 01 00:00:00 EDT 2017
Leptospira interrogans causes quantitative and morphological disturbances in adherens junctions and other biological groups of proteins in human endothelial cells.
PLoS neglected tropical diseases
Sato H,Coburn J
71-1500 was used in Immunocytochemistry to elucidate the pathogenic mechanisms of Leptospira interrogans infection.
Sat Jul 01 00:00:00 EDT 2017
Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite.
PloS one
Jaworska K,Huc T,Samborowska E,Dobrowolski L,Bielinska K,Gawlak M,Ufnal M
71-1500 was used in Immunohistochemistry-immunofluorescence to study the relationship between hypertension and changes in colon permeability to trimethylamine.
Tue Jan 16 00:00:00 EST 2018
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes.
Nature communications
Trietsch SJ,Naumovska E,Kurek D,Setyawati MC,Vormann MK,Wilschut KJ,Lanz HL,Nicolas A,Ng CP,Joore J,Kustermann S,Roth A,Hankemeier T,Moisan A,Vulto P
71-1500 was used in Immunohistochemistry to develop a microfluidic device supporting the growth and function of extracellular matrix-supported intestinal tubules, and evaluate the effect of staurosporine and acetylsalicylic acid on barrier integrity.
Tue Aug 15 00:00:00 EDT 2017
HCV replication in gastrointestinal mucosa: Potential extra-hepatic viral reservoir and possible role in HCV infection recurrence after liver transplantation.
PloS one
Russelli G,Pizzillo P,Iannolo G,Barbera F,Tuzzolino F,Liotta R,Traina M,Vizzini G,Gridelli B,Badami E,Conaldi PG
71-1500 was used in Immunohistochemistry to study the gastrointestinal mucosa as a extrahepatic viral replication site and its contribution to Hepatitis C virus recurrence.
Thu Sep 28 00:00:00 EDT 2017
SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.
Oncogene
Barbáchano A,Fernández-Barral A,Pereira F,Segura MF,Ordóñez-Morán P,Carrillo-de Santa Pau E,González-Sancho JM,Hanniford D,Martínez N,Costales-Carrera A,Real FX,Pálmer HG,Rojas JM,Hernando E,Muñoz A
71-1500 was used in western blot to elucidate the contribution of SPRY2 to colon cancer
Thu Jun 09 00:00:00 EDT 2016
HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24.
Oncogene
Teo WW,Merino VF,Cho S,Korangath P,Liang X,Wu RC,Neumann NM,Ewald AJ,Sukumar S
71-1500 was used in immunocytochemistry and western blot to elucidate regulation of E-cadherin and CD24 by determination of cell fate transition and impeding tumor initiation and progression in breast cancer via HOXA5
Thu Oct 20 00:00:00 EDT 2016
Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis.
Inflammatory bowel diseases
Keppner A,Malsure S,Nobile A,Auberson M,Bonny O,Hummler E
711500 was used in western blot to assess the contribution of mutated prostasin in dextran sodium sulfate-induced colitis
Thu Dec 01 00:00:00 EST 2016
Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells.
Journal of cellular physiology
Villarroel-Espíndola F,Tapia C,González-Stegmaier R,Concha II,Slebe JC
71-1500 was used in western blot to study the effects of glycogen storage in cells from the seminiferous tubules
Sat Oct 01 00:00:00 EDT 2016
Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells.
Journal of cellular physiology
Villarroel-Espíndola F,Tapia C,González-Stegmaier R,Concha II,Slebe JC
71-1500 was used in western blot to study the effects of glycogen storage in cells from the seminiferous tubules
Sat Oct 01 00:00:00 EDT 2016
TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea.
Molecular cancer therapeutics
Wardill HR,Bowen JM,Van Sebille YZ,Secombe KR,Coller JK,Ball IA,Logan RM,Gibson RJ
711500 was used in western blot to study the role of TLR4 in irinotecan-induced diarrhea
Tue Nov 01 00:00:00 EDT 2016
Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity.
Molecular neurobiology
Fernandes S,Salta S,Bravo J,Silva AP,Summavielle T
71-1500 was used in immunocytochemistry and western blot to assess the neuroprotective features of acetyl-L-carnitine in methamphetamine-induced damage.
Fri Jan 01 00:00:00 EST 2016
PEGylation of Reduced Graphene Oxide Induces Toxicity in Cells of the Blood-Brain Barrier: An in Vitro and in Vivo Study.
Molecular pharmaceutics
Mendonça MC,Soares ES,de Jesus MB,Ceragioli HJ,Batista ÂG,Nyúl-Tóth Á,Molnár J,Wilhelm I,Maróstica MR,Krizbai I,da Cruz-Höfling MA
711500 was used in immunocytochemistry to assess the effects of PEGylation on the toxicity of nanoparticles in rat brains
Mon Nov 07 00:00:00 EST 2016
293 cells express both epithelial as well as mesenchymal cell adhesion molecules.
International journal of molecular medicine
Inada M,Izawa G,Kobayashi W,Ozawa M
71-1500 was used in western blot to determine expression of epithelial as well as mesenchymal cell adhesion molecules in 293 cells
Wed Jun 01 00:00:00 EDT 2016
Phenotypic and functional characterization of two bovine mammary epithelial cell lines in 2D and 3D models.
American journal of physiology. Cell physiology
Arévalo Turrubiarte M,Perruchot MH,Finot L,Mayeur F,Dessauge F
71-1500 was used in western blot to study two bovine mammary epithelial cell lines in 2D and 3D models for functional and phenotypic characterization
Tue Mar 01 00:00:00 EST 2016
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats.
Endocrinology
Chen H,Mruk DD,Lee WM,Cheng CY
71-1500 was used in western blot to determine regulation of ectoplasmic specialization dynamics via its effects on actin microfilaments in the testes of male rats by planar cell polarity (PCP) protein Vangl2
Sun May 01 00:00:00 EDT 2016
Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ.
Investigative ophthalmology & visual science
Ji X,Liu Y,Hurd R,Wang J,Fitzmaurice B,Nishina PM,Chang B
71-1500 was used in immunohistochemistry - paraffin section to utilize a novel mouse model with retinal detachment caused by a disruption of protein kinase C, theta, to study retinal pigment epithelium atrophy 1 (rpea1)
Tue Mar 01 00:00:00 EST 2016
Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
American journal of physiology. Gastrointestinal and liver physiology
Vorvis C,Hatziapostolou M,Mahurkar-Joshi S,Koutsioumpa M,Williams J,Donahue TR,Poultsides GA,Eibl G,Iliopoulos D
71-1500 was used in immunohistochemistry identify transcription factors involved in pancreatic ductal adenocarcinoma pathogenesis
Wed Jun 01 00:00:00 EDT 2016
Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions.
Peptides
Yang C,DeMars KM,Hawkins KE,Candelario-Jalil E
71-1500 was used in western blot to study the reduction of paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions by adropin
Fri Jul 01 00:00:00 EDT 2016
Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs.
Molecular medicine reports
Ahn C,Shin DH,Lee D,Kang SM,Seok JH,Kang HY,Jeung EB
711500 was used in immunohistochemistry - paraffin section and western blot to measure tight junction protein expression in canine duodenum, lung, liver, and kidney
Sat Oct 01 00:00:00 EDT 2016
On Chip Bioelectric Impedance Spectroscopy Reveals the Effect of P-Glycoprotein Efflux Pumps on the Paracellular Impedance of Tight Junctions at the Blood-Brain Barrier.
IEEE transactions on nanobioscience
Kraya R,Komin A,Searson P
711500 was used in immunocytochemistry to study the role of P-Glycoprotein in the tight junctions using MCDK cells.
Sat Oct 01 00:00:00 EDT 2016
Rapamycin, a specific inhibitor of the target of rapamycin complex 1, disrupts intestinal barrier integrity in broiler chicks.
Journal of animal physiology and animal nutrition
Liu SQ,Zhao JP,Fan XX,Liu GH,Jiao HC,Wang XJ,Sun SH,Lin H
71-1500 was used in western blot to test if rapamycin-sensitive target of rapamycin complex 1 pathway is involved in intestinal barrier integrity.
Fri Apr 01 00:00:00 EDT 2016
Immunohistological study of tight junction protein expression in mal de Meleda.
Ultrastructural pathology
Kacem M,Agili F,Tounsi H,Zribi H,Zaraa I,Mokni M,Boubaker S
71-1500 was used in immunohistochemistry - paraffin section to analyze tight junction protein expression in mal de Meleda by use of immunohistological studies
Mon Mar 27 00:00:00 EDT 2017
Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis.
PloS one
Stammler A,Lüftner BU,Kliesch S,Weidner W,Bergmann M,Middendorff R,Konrad L
71-1500 was used in western blot examine claudin-11 localization in testis of patients with normal and impaired spermatogenesis
Wed Aug 02 00:00:00 EDT 2017
The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels.
European cells & materials
Lehner C,Gehwolf R,Ek JC,Korntner S,Bauer H,Bauer HC,Traweger A,Tempfer H
71-1500 was used in immunohistochemistry - paraffin section to characterize and identify a novel tissue barrier in tendon blood vessels
Thu May 26 00:00:00 EDT 2016
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.
Scientific reports
Gao Y,Lui WY,Lee WM,Cheng CY
71-1500 was used in western blot report that crumbs homolog 3 is an actin microfilament regulator
Thu Jun 30 00:00:00 EDT 2016
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon.
Scientific reports
Lee SY,Kim H,Kim K,Lee H,Lee S,Lee D
71-1500 was used in immunohistochemistry study the intestinal barrier function using Arhgap17-deficient mice
Fri May 27 00:00:00 EDT 2016
Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43.
Scientific reports
Li N,Mruk DD,Chen H,Wong CK,Lee WM,Cheng CY
71-1500 was used in western blot to characterize overexpression of gap junction protein connexin 43 by rescue of perfluorooctanesulfonate (PFOS)-mediated sertoli cell injury
Wed Jul 20 00:00:00 EDT 2016
T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium.
PloS one
Strazielle N,Creidy R,Malcus C,Boucraut J,Ghersi-Egea JF
71-1500 was used in immunocytochemistry to study a reconstituted choroid plexus epithelium to show T-lymphocytes traffic into the brain across the blood-CSF barrier
Mon Jul 25 00:00:00 EDT 2016
Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models.
Scientific reports
Miquel S,Martín R,Lashermes A,Gillet M,Meleine M,Gelot A,Eschalier A,Ardid D,Bermúdez-Humarán LG,Sokol H,Thomas M,Theodorou V,Langella P,Carvalho FA
71-1500 was used in immunohistochemistry - paraffin section to study the impact of Faecalibacterium prausnitzii in a mouse model of irritable bowel syndrome
Mon Jan 18 00:00:00 EST 2016
Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.
Spermatogenesis
Li N,Lee WM,Cheng CY
711500 was used in western blot to examine the organization of actin microfilaments in Sertoli cell at the blood testis barrier
Fri Apr 01 00:00:00 EDT 2016
A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.
The Journal of biological chemistry
Kitayama M,Mizutani K,Maruoka M,Mandai K,Sakakibara S,Ueda Y,Komori T,Shimono Y,Takai Y
71-1500 was used in Western Blotting to demonstrate that a novel nectin-mediated cell adhesion apparatus regulates the prolactin receptor signaling for mammary gland development.
Fri Mar 11 00:00:00 EST 2016
Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers.
Biomaterials
Staat C,Coisne C,Dabrowski S,Stamatovic SM,Andjelkovic AV,Wolburg H,Engelhardt B,Blasig IE
71-1500 was used in immunocytochemistry to investigate the role of claudin-1/claudin-5 in epithelial/endothelial barriers
Mon Jun 01 00:00:00 EDT 2015
Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa.
The American journal of clinical nutrition
Goichon A,Bertrand J,Chan P,Lecleire S,Coquard A,Cailleux AF,Vaudry D,Déchelotte P,Coëffier M
71-1500 was used in western blot to examine what proteins are produced when carbohydrate-fed healthy humans receive enteral delivery of proteins.
Sat Aug 01 00:00:00 EDT 2015
POF1B localizes to desmosomes and regulates cell adhesion in human intestinal and keratinocyte cell lines.
The Journal of investigative dermatology
Crespi A,Bertoni A,Ferrari I,Padovano V,Della Mina P,Berti E,Villa A,Pietrini G
71-1500 was used in western blot to investigate the localization of POF1B in desmosomes and its role in human intestinal and keratinocyte cell lines
Thu Jan 01 00:00:00 EST 2015
Hydrocortisone enhances the barrier properties of HBMEC/ciβ, a brain microvascular endothelial cell line, through mesenchymal-to-endothelial transition-like effects.
Fluids and barriers of the CNS
Furihata T,Kawamatsu S,Ito R,Saito K,Suzuki S,Kishida S,Saito Y,Kamiichi A,Chiba K
71-1500 was used in western blot to generate a new line of conditionally immortalized human brain microvascular endothelial cells to study blood brain barrier function
Thu Mar 12 00:00:00 EDT 2015
Immune quiescence of the brain is set by astroglial connexin 43.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Boulay AC,Mazeraud A,Cisternino S,Saubaméa B,Mailly P,Jourdren L,Blugeon C,Mignon V,Smirnova M,Cavallo A,Ezan P,Avé P,Dingli F,Loew D,Vieira P,Chrétien F,Cohen-Salmon M
71-1500 was used in western blot to study the role of astroglial cx43 in immune quiescence of the brain
Wed Mar 11 00:00:00 EDT 2015
Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats.
Frontiers in molecular neuroscience
Sántha P,Veszelka S,Hoyk Z,Mészáros M,Walter FR,Tóth AE,Kiss L,Kincses A,Oláh Z,Seprényi G,Rákhely G,Dér A,Pákáski M,Kálmán J,Kittel Á,Deli MA
71-1500 was used in immunohistochemistry - free floating to evaluate the blood-brain barrier in adult rats and morphological changes due to restraint stress-induction
Tue Feb 02 00:00:00 EST 2016
Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li N,Mruk DD,Wong CK,Lee WM,Han D,Cheng CY
71-1500 was used in western blot to study the role of plastin 3 in ectoplasmic specialization dynamics during spermatogenesis in the rat testis
Tue Sep 01 00:00:00 EDT 2015
The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Kreft ME,Jerman UD,Lasič E,Hevir-Kene N,Rižner TL,Peternel L,Kristan K
71-1500 was used in immunocytochemistry to assess the effects of different cell culturing conditions on the Calu-3 epithelial cell model.
Tue Mar 10 00:00:00 EDT 2015
EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study.
Endocrinology
Tang EI,Mok KW,Lee WM,Cheng CY
71-1500 was used in western blot to study the role of EB1 in tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier
Sun Feb 01 00:00:00 EST 2015
The characterization of the human nasal epithelial cell line RPMI 2650 under different culture conditions and their optimization for an appropriate in vitro nasal model.
Pharmaceutical research
Kreft ME,Jerman UD,Lasič E,Lanišnik Rižner T,Hevir-Kene N,Peternel L,Kristan K
71-1500 was used in immunocytochemistry to study using RPMI 2650 cells to create an in vitro model of the nasal mucosa.
Sun Feb 01 00:00:00 EST 2015
Low-dose endothelial monocyte-activating polypeptide-II increases permeability of blood-tumor barrier via a PKC-ζ/PP2A-dependent signaling mechanism.
Experimental cell research
Li Z,Liu YH,Liu XB,Xue YX,Wang P,Liu LB
71-1500 was used in immunoprecipitation and western blot to report the signaling mechanisms by which PKC-ζ activation affects EMAP-II-induced BTB hyperpermeability.
Sun Feb 15 00:00:00 EST 2015
Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways.
Experimental cell research
Martínez-Revollar G,Garay E,Martin-Tapia D,Nava P,Huerta M,Lopez-Bayghen E,Meraz-Cruz N,Segovia J,González-Mariscal L
71-1500 was used in immunocytochemistry and western blot to characterize two clones from triple negative breast MDA-MB-231 cancer cells
Sun Nov 15 00:00:00 EST 2015
Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress.
Molecular biology of the cell
ErLin S,WenJie W,LiNing W,BingXin L,MingDe L,Yan S,RuiFa H
71-1500 was used in western blot to study the role of Musashi-1 in blood-testis barrier structure during spermatogenesis
Fri May 15 00:00:00 EDT 2015
OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats.
Molecular medicine reports
Kim CS,Kim J,Jo K,Lee YM,Sohn E,Yoo NH,Kim JS
71-1500 was used in western blot to examine the effect of advanced glycation end products on the retina
Sun Nov 01 00:00:00 EDT 2015
Azithromycin attenuates cigarette smoke extract-induced oxidative stress injury in human alveolar epithelial cells.
Molecular medicine reports
Chen M,Yang T,Meng X,Sun T
71-1500 was used in immunocytochemistry and western blot to test if azithromycin attenuates cigarette smoke extract-induced A549 cell oxidative stress injury
Fri May 01 00:00:00 EDT 2015
Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas).
Reproductive toxicology (Elmsford, N.Y.)
Ek CJ,D'Angelo B,Lehner C,Nathanielsz P,Li C,Mallard C
71-1500 was used in immunohistochemistry - paraffin section and western blot to study the choroid plexus in the fetus.
Sat Aug 15 00:00:00 EDT 2015
Ligustrazine reduces blood-brain barrier permeability in a rat model of focal cerebral ischemia and reperfusion.
Experimental and therapeutic medicine
Tan F,Fu W,Cheng N,Meng DI,Gu Y
71-1500 was used in western blot to test if 2,3,5,6-tetramethylpyrazine protects the blood brain barries integrity in ischemia/reperfusion injury.
Fri May 01 00:00:00 EDT 2015
Injury to the blood-testis barrier after low-dose-rate chronic radiation exposure in mice.
Radiation protection dosimetry
Son Y,Heo K,Bae MJ,Lee CG,Cho WS,Kim SD,Yang K,Shin IS,Lee MY,Kim JS
71-1500 was used in western blot to determine effects of low-dose-rate chronic radiation on male fertility.
Sun Nov 01 00:00:00 EDT 2015
HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model.
Biochimica et biophysica acta
Suárez-Causado A,Caballero-Díaz D,Bertrán E,Roncero C,Addante A,García-Álvaro M,Fernández M,Herrera B,Porras A,Fabregat I,Sánchez A
71-1500 was used in western blot to determine the role of the HGF/c-Met pathway in regulating oval cell migratory and invasive properties.
Thu Oct 01 00:00:00 EDT 2015
Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system.
The Journal of biological chemistry
Muramatsu R,Kuroda M,Matoba K,Lin H,Takahashi C,Koyama Y,Yamashita T
71-1500 was used in western blot to investigate the effect of prostacyclin on pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system
Fri May 01 00:00:00 EDT 2015
Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota.
Nature communications
Chang CJ,Lin CS,Lu CC,Martel J,Ko YF,Ojcius DM,Tseng SF,Wu TR,Chen YY,Young JD,Lai HC
71-1500 was used in western blot to study modulation of the composition of the gut microbiota by ganoderma lucidum that reduces obesity in mice
Tue Jun 23 00:00:00 EDT 2015
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure.
Liver international : official journal of the International Association for the Study of the Liver
Chastre A,Bélanger M,Nguyen BN,Butterworth RF
71-1500 was used in western blot to study the effect of endotoxemia on the progression of encephalopathy in relation to BBB permeability during acute liver failure
Sat Mar 01 00:00:00 EST 2014
Alteration of intestinal barrier function during activity-based anorexia in mice.
Clinical nutrition (Edinburgh, Scotland)
Jésus P,Ouelaa W,François M,Riachy L,Guérin C,Aziz M,Do Rego JC,Déchelotte P,Fetissov SO,Coëffier M
71-1500 was used in immunocytochemistry and western blot to study the effect of activity-based anorexia on intestinal barrier function in mice
Mon Dec 01 00:00:00 EST 2014
Neurovascular protection by post-ischemic intravenous injections of the lipoxin A4 receptor agonist, BML-111, in a rat model of ischemic stroke.
Journal of neurochemistry
Hawkins KE,DeMars KM,Singh J,Yang C,Cho HS,Frankowski JC,Doré S,Candelario-Jalil E
71-1500 was used in western blot to evaluate the neuroprotective effect of the lipoxin A4 receptor agonist, BML-111, in a rat model of ischemic stroke
Tue Apr 01 00:00:00 EDT 2014
β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier.
Journal of immunology (Baltimore, Md. : 1950)
Gorina R,Lyck R,Vestweber D,Engelhardt B
71-1500 was used in immunocytochemistry to investigate mechanisms that govern neutrophil migration across the blood brain barrier.
Wed Jan 01 00:00:00 EST 2014
2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling.
World journal of gastroenterology
Loeuillard E,Bertrand J,Herranen A,Melchior C,Guérin C,Coëffier M,Aziz M,Déchelotte P,Savoye G,Marion-Letellier R
71-1500 was used in western blot to evalute the therapeutic potential of proteasome inhibition for intestinal fibrosis in rats.
Sun Dec 28 00:00:00 EST 2014
Cholera toxin enhances Na(+) absorption across MCF10A human mammary epithelia.
American journal of physiology. Cell physiology
Wang Q,Schultz BD
71-1500 was used in western blot to study the role of ENaC in the mechanism by which cholera toxin mediates increased human mammary epithelial sodium uptake.
Sat Mar 01 00:00:00 EST 2014
rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Journal of cell science
Mok KW,Mruk DD,Cheng CY
Sat Nov 15 00:00:00 EST 2014
rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Journal of cell science
Mok KW,Mruk DD,Cheng CY
Sat Nov 15 00:00:00 EST 2014
Alternative endocytosis pathway for productive entry of hepatitis C virus.
The Journal of general virology
Matsuda M,Suzuki R,Kataoka C,Watashi K,Aizaki H,Kato N,Matsuura Y,Suzuki T,Wakita T
71-1500 was used in western blot to investigate the mechanisms of hepatitis C virus entry into multiple permissive human hepatocyte-derived cells
Mon Dec 01 00:00:00 EST 2014
Local VEGF inhibition prevents ovarian alterations associated with ovarian hyperstimulation syndrome.
The Journal of steroid biochemistry and molecular biology
Scotti L,Abramovich D,Pascuali N,Irusta G,Meresman G,Tesone M,Parborell F
71-1500 was used in western blot to study the role of vascular endothelial growth factor A in ovarian hyperstimulation syndrome
Wed Oct 01 00:00:00 EDT 2014
The angiopoietin1-Akt pathway regulates barrier function of the cultured spinal cord microvascular endothelial cells through Eps8.
Experimental cell research
Liu X,Zhou X,Yuan W
71-1500 was used in immunohistochemistry and western blot to investigate their role of angiopoietin 1 in regulating the blood-spinal cord barrier
Wed Oct 15 00:00:00 EDT 2014
HGF and the regulation of tight junctions in human prostate cancer cells.
Oncology reports
Martin TA,Mason MD,Jiang WG
71-1500 was used in western blot to determine the effect of HGF on the function of tight junctions in human prostate epithelial, prostate stem cell-like, and prostate cancer cell lines
Tue Jul 01 00:00:00 EDT 2014
Disrupted tight junctions in the small intestine of cystic fibrosis mice.
Cell and tissue research
De Lisle RC
71-1500 was used in immunohistochemistry and western blot to characterize tight junctions in the digestive tract of cystic fibrosis mice
Wed Jan 01 00:00:00 EST 2014
Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome.
Journal of the Formosan Medical Association = Taiwan yi zhi
Lee JD,Lee MH
71-1500 was used in immunocytochemistry, immunohistochemistry - paraffin section, and western blot to study the expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome
Wed Jan 01 00:00:00 EST 2014
IL-1β and TGF-β weaken the placental barrier through destruction of tight junctions: an in vivo and in vitro study.
Placenta
Tossetta G,Paolinelli F,Avellini C,Salvolini E,Ciarmela P,Lorenzi T,Emanuelli M,Toti P,Giuliante R,Gesuita R,Crescimanno C,Voltolini C,Di Primio R,Petraglia F,Castellucci M,Marzioni D
71-1500 was used in immunohistochemistry and western blot to investigate chorioamnionitis.
Tue Jul 01 00:00:00 EDT 2014
p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes.
Archives of dermatological research
Siljamäki E,Raiko L,Toriseva M,Nissinen L,Näreoja T,Peltonen J,Kähäri VM,Peltonen S
71-1500 was used in western blot to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes
Sat Mar 01 00:00:00 EST 2014
Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Price DB,Ackland ML,Burks W,Knight MI,Suphioglu C
71-1500 was used in immunocytochemistry to investigate the effect of peanut allergens on intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures
Mon Sep 21 00:00:00 EDT 2015
Regulation of the inflammasome by ceramide in cystic fibrosis lungs.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Grassmé H,Carpinteiro A,Edwards MJ,Gulbins E,Becker KA
71-1500 was used in immunohistochemistry - paraffin section to demonstrate that ceramide accumulates in cystic fibrosis lungs and mediates increased cell death, susceptibility to infections, and inflammation
Fri Feb 20 00:00:00 EST 2015
Chlorogenic acid decreases intestinal permeability and increases expression of intestinal tight junction proteins in weaned rats challenged with LPS.
PloS one
Ruan Z,Liu S,Zhou Y,Mi S,Liu G,Wu X,Yao K,Assaad H,Deng Z,Hou Y,Wu G,Yin Y
71-1500 was used in immunohistochemistry - paraffin section and western blot to test if chlorogenic acid improves the intestinal barrier integrity of weaned rats treated with lipopolysaccharide.
Wed Jan 28 00:00:00 EST 2015
Diurnal variation of tight junction integrity associates inversely with matrix metalloproteinase expression in Xenopus laevis corneal epithelium: implications for circadian regulation of homeostatic surface cell desquamation.
PloS one
Wiechmann AF,Ceresa BP,Howard EW
71-1500 was used in immunohistochemistry - frozen section to investigate matrix metalloproteinase expression in the Xenopus laevis corneal epithelium
Tue Dec 22 00:00:00 EST 2015
PLEKHA7 modulates epithelial tight junction barrier function.
Tissue barriers
Paschoud S,Jond L,Guerrera D,Citi S
71-1500 was used in immunocytochemistry to test whether PLEKHA7 protein modulates epithelial tight junction barrier function
Wed Jan 01 00:00:00 EST 2014
Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells.
PloS one
Cai X,Dai Z,Reeves RS,Caballero-Benitez A,Duran KL,Delrow JJ,Porter PL,Spies T,Groh V
71-1500 was used in immunocytochemistry and western blot to analyze cancer cell plasticity autonomous stimulation by human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells
Wed Jun 10 00:00:00 EDT 2015
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity.
Nature communications
Yao Y,Chen ZL,Norris EH,Strickland S
71-1500 was used in immunohistochemistry and western blot to find that astrocytic laminin maintains the blood brain barrier by regulating pericyte differentiation.
Mon Mar 03 00:00:00 EST 2014
Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.
PloS one
Johnson HL,Willenbring RC,Jin F,Manhart WA,LaFrance SJ,Pirko I,Johnson AJ
71-1500 was used in immunohistochemistry to examine the role of perforin and CD8 T cells in immune-mediated blood-brain barrier disruption
Thu Dec 17 00:00:00 EST 2015
Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors.
Cancer cell
Schwitalla S,Ziegler PK,Horst D,Becker V,Kerle I,Begus-Nahrmann Y,Lechel A,Rudolph KL,Langer R,Slotta-Huspenina J,Bader FG,Prazeres da Costa O,Neurath MF,Meining A,Kirchner T,Greten FR
71-1500 was used in Immunohistochemistry to demonstrate that loss of p53 alone is insufficient to initiate intestinal tumorigenesis but enhances carcinogen-induced tumor incidence.
Mon Jan 14 00:00:00 EST 2013
Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions.
Cell host & microbe
Guichard A,Cruz-Moreno B,Aguilar B,van Sorge NM,Kuang J,Kurkciyan AA,Wang Z,Hang S,Pineton de Chambrun GP,McCole DF,Watnick P,Nizet V,Bier E
71-1500 was used in immunocytochemistry to study how Rab inhibits the barrier-disrupting effects of CtxA.
Wed Sep 11 00:00:00 EDT 2013
Organotypic brain slices: a model to study the neurovascular unit micro-environment in epilepsies.
Fluids and barriers of the CNS
Morin-Brureau M,De Bock F,Lerner-Natoli M
71-1500 was used in western blot to develop an organotypic brain slice culture as a model to study the role of the neurovascular unit in epilepsy and other neurological disorders.
Thu Feb 07 00:00:00 EST 2013
miR-199a-5p regulates urothelial permeability and may play a role in bladder pain syndrome.
The American journal of pathology
Monastyrskaya K,Sánchez-Freire V,Hashemi Gheinani A,Klumpp DJ,Babiychuk EB,Draeger A,Burkhard FC
71-1500 was used in immunocytochemistry and western blot to show that miR-99a-5p regulates intercellular junctions in the bladder.
Fri Feb 01 00:00:00 EST 2013
Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.
Experimental neurology
Teng F,Beray-Berthat V,Coqueran B,Lesbats C,Kuntz M,Palmier B,Garraud M,Bedfert C,Slane N,Bérézowski V,Szeremeta F,Hachani J,Scherman D,Plotkine M,Doan BT,Marchand-Leroux C,Margaill I
71-1500 was used in western blot to evaluate the protective effect of the poly(ADP-ribose)polymerase inhibitor PJ34 against vascular toxicity
Tue Oct 01 00:00:00 EDT 2013
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells.
Journal of cell science
Ngan E,Northey JJ,Brown CM,Ursini-Siegel J,Siegel PM
71-1500 was used in western blot to show that epithelial-derived breast cancer cells use signaling molecules that normally facilitate cellular migration and invasion of mesenchymal cells
Wed May 01 00:00:00 EDT 2013
Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation.
Journal of cell science
Elsum IA,Martin C,Humbert PO
71-1500 was used in immunocytochemistry and western blot to assess the role of the Scribble polarity module.
Sun Sep 01 00:00:00 EDT 2013
Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-β by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro.
Neurobiology of aging
Shimizu F,Sano Y,Tominaga O,Maeda T,Abe MA,Kanda T
71-1500 was used in western blot to identify the mechanisms responsible for the disruption of the blood brain barrier after exposure to advanced glycation end-products.
Mon Jul 01 00:00:00 EDT 2013
Microvascular permeability to water is independent of shear stress, but dependent on flow direction.
American journal of physiology. Heart and circulatory physiology
Adamson RH,Sarai RK,Altangerel A,Clark JF,Weinbaum S,Curry FE
71-1500 was used in immunohistochemistry to test if the stable permeability state of individually perfused microvessels is characteristic of flow conditioning.
Mon Apr 15 00:00:00 EDT 2013
Short-chain fatty acids activate AMP-activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers.
The Journal of nutrition
Elamin EE,Masclee AA,Dekker J,Pieters HJ,Jonkers DM
71-1500 was used in immunocytochemistry to analyze the influence of SCFAs and AMP-activated protein kinase on ethanol-induced barrier dysfunction.
Sun Dec 01 00:00:00 EST 2013
Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat.
The Journal of endocrinology
Xiao X,Cheng CY,Mruk DD
71-1500 was used in western blot to assess the role of intercellular adhesion molecule-2 in the testis
Tue Jan 01 00:00:00 EST 2013
Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation.
Molecular and cellular endocrinology
Nicholls PK,Harrison CA,Rainczuk KE,Wayne Vogl A,Stanton PG
71-1500 was used in western blot to study the cellular and molecular basis of retinoid actions upon Sertoli cell differentiation.
Thu Sep 05 00:00:00 EDT 2013
SOX8 regulates permeability of the blood-testes barrier that affects adult male fertility in the mouse.
Biology of reproduction
Singh AP,Cummings CA,Mishina Y,Archer TK
71-1500 was used in immunohistochemistry - paraffin section to determine the level of tight junction proteins and blood-testes barrier permeability in Sox8(-/-) adult testes.
Wed May 01 00:00:00 EDT 2013
Papillomavirus E6 oncoprotein up-regulates occludin and ZO-2 expression in ovariectomized mice epidermis.
Experimental cell research
Hernández-Monge J,Garay E,Raya-Sandino A,Vargas-Sierra O,Díaz-Chávez J,Popoca-Cuaya M,Lambert PF,González-Mariscal L,Gariglio P
71-1500 was used in western blot to investigate the expression of the tight junction proteins occludin, claudin-1 and ZO-2 in the epidermis of female mice.
Tue Oct 15 00:00:00 EDT 2013
Ameliorative effect of PACAP and VIP against increased permeability in a model of outer blood retinal barrier dysfunction.
Peptides
Scuderi S,D'Amico AG,Castorina A,Imbesi R,Carnazza ML,D'Agata V
71-1500 was used in western blot to study changes in the blood retinal barrier in diabetic macular edema.
Tue Jan 01 00:00:00 EST 2013
Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.
Nature communications
Castelli M,Boca M,Chiaravalli M,Ramalingam H,Rowe I,Distefano G,Carroll T,Boletta A
71-1500 was used in immunohistochemistry to demonstrate that PC- regulates correct tubular diameter during nephron development.
Thu Jun 12 00:00:00 EDT 2014
Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis.
PloS one
Rachow S,Zorn-Kruppa M,Ohnemus U,Kirschner N,Vidal-y-Sy S,von den Driesch P,Börnchen C,Eberle J,Mildner M,Vettorazzi E,Rosenthal R,Moll I,Brandner JM
71-1500 was used in immunocytochemistry and western blot to observe changes in tight junction proteins in various epithelial tumors
Fri Jul 19 00:00:00 EDT 2013
NC1 domain of collagen α3(IV) derived from the basement membrane regulates Sertoli cell blood-testis barrier dynamics.
Spermatogenesis
Wong EW,Cheng CY
71-1500 was used in western blot to study how Sertoli cell blood-testis +C309:C312 barrier dynamics are regulated by the NC1 domain of collagen alpha3(IV) derived from the basement membrane
Mon Apr 01 00:00:00 EDT 2013
The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin.
PloS one
Shiobara T,Usui T,Han J,Isoda H,Nagumo Y
71-1500 was used in immunocytochemistry and western blot to study the molecular mechanisms underlying the reversible effects of capsaicin on tight junction permeability.
Mon Jul 07 00:00:00 EDT 2014
Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat.
Proceedings of the National Academy of Sciences of the United States of America
Lie PP,Mruk DD,Mok KW,Su L,Lee WM,Cheng CY
Tue Jul 31 00:00:00 EDT 2012
An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch.
Cancer letters
Jahn SC,Law ME,Corsino PE,Parker NN,Pham K,Davis BJ,Lu J,Law BK
71-1500 was used in western blot to study mitogenic signaling changes during the epithelial-mesenchymal transition in an in vivo model.
Sun Dec 30 00:00:00 EST 2012
Heterogeneity in the rat brain vasculature revealed by quantitative confocal analysis of endothelial barrier antigen and P-glycoprotein expression.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Saubaméa B,Cochois-Guégan V,Cisternino S,Scherrmann JM
71-1500 was used in immunohistochemistry to characterize P-glycoprotein and endothelial barrier antigen in the rat brain.
Sun Jan 01 00:00:00 EST 2012
Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function.
The American journal of pathology
Patel RM,Myers LS,Kurundkar AR,Maheshwari A,Nusrat A,Lin PW
71-1500 was used in western blot to report that commensal colonization induces intestinal barrier function maturation by promoting claudin 3 expression.
Wed Feb 01 00:00:00 EST 2012
CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil support.
Journal of immunology (Baltimore, Md. : 1950)
Johnson HL,Chen Y,Jin F,Hanson LM,Gamez JD,Pirko I,Johnson AJ
71-1500 was used in immunocytochemistry to determine the contribution of neutrophils to central nervous system vascular permeability.
Wed Aug 15 00:00:00 EDT 2012
Effect of Phoneutria nigriventer venom on the expression of junctional protein and P-gp efflux pump function in the blood-brain barrier.
Neurochemical research
Rapôso C,Odorissi PA,Oliveira AL,Aoyama H,Ferreira CV,Verinaud L,Fontana K,Ruela-de-Sousa RR,da Cruz-Höfling MA
71-1500 was used in western blot to use Phoneutria nigriventer spider venom to study the blood brain barrier.
Sat Sep 01 00:00:00 EDT 2012
Hepatocyte growth factor (HGF) regulates blood-testis barrier (BTB) in adult rats.
Molecular and cellular endocrinology
Catizone A,Ricci G,Caruso M,Ferranti F,Canipari R,Galdieri M
71-1500 was used in immunohistochemistry and western blot to report that HGF reduces the amount of actin present in the BTB region.
Mon Jan 02 00:00:00 EST 2012
CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus.
Biology of reproduction
Reardon SN,King ML,MacLean JA,Mann JL,DeMayo FJ,Lydon JP,Hayashi K
71-1500 was used in immunohistochemistry to elucidate the role of CDH in the mouse uterus.
Tue May 01 00:00:00 EDT 2012
Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells.
Infection and immunity
Lécuyer H,Nassif X,Coureuil M
Sun Jan 01 00:00:00 EST 2012
Occludin dislocation in brain capillary endothelium of rats with bile duct ligation induced cholestasis.
Neuroscience letters
Mavrakis AG,Havaki S,Marinos E,Chroni E,Konstantinou D
71-1500 was used in immunohistochemistry - free floating to examine the effect of cholestasis to the localization of occludin in brain capillary endothelium.
Wed Oct 24 00:00:00 EDT 2012
Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility.
International journal of andrology
Mok KW,Mruk DD,Lee WM,Cheng CY
Wed Feb 01 00:00:00 EST 2012
Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility.
International journal of andrology
Mok KW,Mruk DD,Lee WM,Cheng CY
Wed Feb 01 00:00:00 EST 2012
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis.
Spermatogenesis
Tang EI,Xiao X,Mruk DD,Qian XJ,Mok KW,Jenardhanan P,Lee WM,Mathur PP,Cheng CY
71-1500 was used in western blot to examine the role of actin and tubulin in ectoplasmic specialization
Sun Apr 01 00:00:00 EDT 2012
Role of tight junction proteins in gastroesophageal reflux disease.
BMC gastroenterology
Mönkemüller K,Wex T,Kuester D,Fry LC,Kandulski A,Kropf S,Roessner A,Malfertheiner P
71-1500 was used in immunohistochemistry to determine the expression pattern of selected components involved in the formation of tight junctions in relation to gastroesophageal reflux disease
Thu Sep 20 00:00:00 EDT 2012
Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression.
PloS one
Leung C,Shaheen F,Bernatchez P,Hackett TL
71-1500 was used in western blot to study the function of dysferlin and myoferlin in airway epithelial homeostasis.
Tue Mar 19 00:00:00 EDT 2013
GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier.
Regulatory peptides
Moran GW,O'Neill C,McLaughlin JT
71-1500 was used in western blot to test if GLP-2 regulates tight junctions.
Wed Oct 10 00:00:00 EDT 2012
Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton.
Spermatogenesis
Lydka M,Bilinska B,Cheng CY,Mruk DD
71-1500 was used in western blot to examine the effects of TNFalpha on Sertoli cell barrier function
Mon Oct 01 00:00:00 EDT 2012
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.
Science (New York, N.Y.)
Alvarez JI,Dodelet-Devillers A,Kebir H,Ifergan I,Fabre PJ,Terouz S,Sabbagh M,Wosik K,Bourbonnière L,Bernard M,van Horssen J,de Vries HE,Charron F,Prat A
Fri Dec 23 00:00:00 EST 2011
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.
Science (New York, N.Y.)
Alvarez JI,Dodelet-Devillers A,Kebir H,Ifergan I,Fabre PJ,Terouz S,Sabbagh M,Wosik K,Bourbonnière L,Bernard M,van Horssen J,de Vries HE,Charron F,Prat A
Fri Dec 23 00:00:00 EST 2011
Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis.
Acta neuropathologica
Pfeiffer F,Schäfer J,Lyck R,Makrides V,Brunner S,Schaeren-Wiemers N,Deutsch U,Engelhardt B
71-1500 was used in immunohistochemistry (frozen) to assess the effects of stabilizing the blood brain barrier function by therapeutic targeting tight junction proteins for experimental autoimmune encephalomyelitis.
Tue Nov 01 00:00:00 EDT 2011
Ouabain modulates ciliogenesis in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America
Larre I,Castillo A,Flores-Maldonado C,Contreras RG,Galvan I,Muñoz-Estrada J,Cereijido M
71-1500 was used in immunocytochemistry to investigate the effect of ouabain on cilia development in epithelial cells
Tue Dec 20 00:00:00 EST 2011
Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.
Annals of neurology
Tang XN,Zheng Z,Giffard RG,Yenari MA
71-1500 was used in western blot to assess the effect of NOX2 derived from immune cells in the brain and in blood cells in experimental stroke.
Sat Oct 01 00:00:00 EDT 2011
Tight junctions in brain barriers during central nervous system inflammation.
Antioxidants & redox signaling
Coisne C,Engelhardt B
71-1500 was used in immunohistochemistry to discuss the mechanisms by which the blood brain barrier and the blood-cerebrospinal fluid barrier are dysregulated during inflammation.
Thu Sep 01 00:00:00 EDT 2011
Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.
Journal of virology
Brimacombe CL,Grove J,Meredith LW,Hu K,Syder AJ,Flores MV,Timpe JM,Krieger SE,Baumert TF,Tellinghuisen TL,Wong-Staal F,Balfe P,McKeating JA
Sat Jan 01 00:00:00 EST 2011
Roles of pre-treatment time and junctional proteins in Caco-2 cell microparticle uptake.
International journal of pharmaceutics
Moyes SM,Morris JF,Carr KE
71-1500 was used in immunocytochemistry to assess the effects of ethanol or ice on transepithelial resistance and microparticle uptake using Caco-2 cells.
Mon Apr 04 00:00:00 EDT 2011
Microglia/macrophages migrate through retinal epithelium barrier by a transcellular route in diabetic retinopathy: role of PKCζ in the Goto Kakizaki rat model.
The American journal of pathology
Omri S,Behar-Cohen F,de Kozak Y,Sennlaub F,Verissimo LM,Jonet L,Savoldelli M,Omri B,Crisanti P
71-1500 was used in immunohistochemistry to study microglia/macrophages trafficking and the role of protein kinase Cζ in diabetic retinopathy.
Mon Aug 01 00:00:00 EDT 2011
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.
The international journal of biochemistry & cell biology
Xiao X,Mruk DD,Lee WM,Cheng CY
71-1500 was used in immunohistochemistry - frozen section and western blot to elucidate how c-Yes regulates the blood-testis barrier and apical ectoplasmic specialization integrity.
Fri Apr 01 00:00:00 EDT 2011
c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.
The international journal of biochemistry & cell biology
Xiao X,Mruk DD,Lee WM,Cheng CY
71-1500 was used in immunohistochemistry - frozen section and western blot to elucidate how c-Yes regulates the blood-testis barrier and apical ectoplasmic specialization integrity.
Fri Apr 01 00:00:00 EDT 2011
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Fredenburgh LE,Velandia MM,Ma J,Olszak T,Cernadas M,Englert JA,Chung SW,Liu X,Begay C,Padera RF,Blumberg RS,Walsh SR,Baron RM,Perrella MA
Tue Nov 15 00:00:00 EST 2011
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Fredenburgh LE,Velandia MM,Ma J,Olszak T,Cernadas M,Englert JA,Chung SW,Liu X,Begay C,Padera RF,Blumberg RS,Walsh SR,Baron RM,Perrella MA
Tue Nov 15 00:00:00 EST 2011
Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells.
Molecular biology of the cell
Dukes JD,Fish L,Richardson JD,Blaikley E,Burns S,Caunt CJ,Chalmers AD,Whitley P
Thu Sep 01 00:00:00 EDT 2011
Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall.
Immunobiology
Blank F,Wehrli M,Lehmann A,Baum O,Gehr P,von Garnier C,Rothen-Rutishauser BM
71-1500 was used in immunocytochemistry to study barrier integrity and tight junction protein expression using in vitro lung epithelial barrier model
Mon Jul 18 00:00:00 EDT 2011
Comparison of tight junction protein expression in the ciliary epithelia of mouse, rabbit, cat and human eyes.
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Karim MJ,Biswas S,Bhattacherjee P,Paterson CA
71-1500 was used in immunohistochemistry to investigate if the expression pattern of tight junction proteins in mice, rabbits, and cats resemble those of humans
Wed Jun 01 00:00:00 EDT 2011
Immunomapping of desmosomal and nondesmosomal adhesion molecules in healthy canine footpad, haired skin and buccal mucosal epithelia: comparison with canine pemphigus foliaceus serum immunoglobulin G staining patterns.
Veterinary dermatology
Bizikova P,Linder KE,Olivry T
71-1500 was used in Immunohistochemistry-immunofluorescence to confirm the immunological heterogeneity of cPF immunoglobulin G autoantibodies. Moreover, the major indirect immunofluorescence staining pattern and the inability of most cPF sera to label the buccal mucosa closely matched that of desmocollin-1.
Fri Apr 01 00:00:00 EDT 2011
Immunomapping of desmosomal and nondesmosomal adhesion molecules in healthy canine footpad, haired skin and buccal mucosal epithelia: comparison with canine pemphigus foliaceus serum immunoglobulin G staining patterns.
Veterinary dermatology
Bizikova P,Linder KE,Olivry T
71-1500 was used in Immunohistochemistry-immunofluorescence to confirm the immunological heterogeneity of cPF immunoglobulin G autoantibodies. Moreover, the major indirect immunofluorescence staining pattern and the inability of most cPF sera to label the buccal mucosa closely matched that of desmocollin-1.
Fri Apr 01 00:00:00 EDT 2011
The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components.
Brain, behavior, and immunity
Alikunju S,Abdul Muneer PM,Zhang Y,Szlachetka AM,Haorah J
71-1500 was used in Immunohistochemistry to reveal the underlying mechanisms that ethanol-elicited BBB oxidative damage initiates the brain vascular inflammatory process, which ultimately leads to neuroinflammation.
Wed Jun 01 00:00:00 EDT 2011
Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain: comparison with sporadic colon carcinoma.
Diagnostic pathology
Mikami T,Yoshida T,Numata Y,Kikuchi M,Araki K,Nakada N,Okayasu I
Thu Apr 07 00:00:00 EDT 2011
A study to assess the assembly of a functional blood-testis barrier in developing rat testes.
Spermatogenesis
Mok KW,Mruk DD,Lee WM,Cheng CY
71-1500 was used in Immunofluorescence in immunohistochemistry on frozen tissues to identify a precise time window when the blood-testis barrier is established in the developing rat testis during the final stage of cell cycle progression and meiosis.
Fri Jul 01 00:00:00 EDT 2011
A study to assess the assembly of a functional blood-testis barrier in developing rat testes.
Spermatogenesis
Mok KW,Mruk DD,Lee WM,Cheng CY
71-1500 was used in Immunofluorescence in immunohistochemistry on frozen tissues to identify a precise time window when the blood-testis barrier is established in the developing rat testis during the final stage of cell cycle progression and meiosis.
Fri Jul 01 00:00:00 EDT 2011
A study to assess the assembly of a functional blood-testis barrier in developing rat testes.
Spermatogenesis
Mok KW,Mruk DD,Lee WM,Cheng CY
71-1500 was used in Immunofluorescence in immunohistochemistry on frozen tissues to identify a precise time window when the blood-testis barrier is established in the developing rat testis during the final stage of cell cycle progression and meiosis.
Fri Jul 01 00:00:00 EDT 2011
Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis.
The Journal of biological chemistry
Durgan J,Kaji N,Jin D,Hall A
71-1500 was used in immunocytochemistry to investigate the role of Cdc42 in polarization of epithelial cells.
Fri Apr 08 00:00:00 EDT 2011
Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells.
Gastroenterology
Chang TL,Ito K,Ko TK,Liu Q,Salto-Tellez M,Yeoh KG,Fukamachi H,Ito Y
71-1500 was used in Western Blotting to identify RUNX3 target genes that promote cell-cell contact in gastric epithelial cells.
Fri Jan 01 00:00:00 EST 2010
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.
Diabetes
Leal EC,Martins J,Voabil P,Liberal J,Chiavaroli C,Bauer J,Cunha-Vaz J,Ambrósio AF
Fri Oct 01 00:00:00 EDT 2010
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.
Diabetes
Leal EC,Martins J,Voabil P,Liberal J,Chiavaroli C,Bauer J,Cunha-Vaz J,Ambrósio AF
Fri Oct 01 00:00:00 EDT 2010
Ascorbate protects endothelial barrier function during septic insult: Role of protein phosphatase type 2A.
Free radical biology & medicine
Han M,Pendem S,Teh SL,Sukumaran DK,Wu F,Wilson JX
71-1500 was used in immunocytochemistry and immunoprecipitation to test if increasing ascorbate protects the endothelial barrier from septic insult by inhibiting protein phosphatase type 2A
Fri Jan 01 00:00:00 EST 2010
Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Bauer AT,Bürgers HF,Rabie T,Marti HH
71-1500 was used in immunohistochemistry and western blot to examine the effect of prolonged hypoxia on blood-brain barrier integrity in vivo
Thu Apr 01 00:00:00 EDT 2010
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.
The Journal of physiology
LeSimple P,Liao J,Robert R,Gruenert DC,Hanrahan JW
71-1500 was used in western blot to elucidate the role of cystic fibrosis transmembrane conductance regulator in epithelial tightness
Thu Apr 15 00:00:00 EDT 2010
Loss of occludin leads to the progression of human breast cancer.
International journal of molecular medicine
Martin TA,Mansel RE,Jiang WG
71-1500 was used in immunocytochemistry, immunohistochemistry, and western blot to elucidate the contribution of occludin to human breast cancer
Mon Nov 01 00:00:00 EDT 2010
Assessing the role of claudins in maintaining the integrity of epididymal tight junctions using novel human epididymal cell lines.
Biology of reproduction
Dubé E,Dufresne J,Chan PT,Hermo L,Cyr DG
71-1500 was used in immunocytochemistry to generate and characterize 2 human epidermis-derived cell lines
Tue Jun 01 00:00:00 EDT 2010
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.
Experimental cell research
Su L,Mruk DD,Lee WM,Cheng CY
71-1500 was used in immunocytochemistry, immunoprecipitation, and western blot to study protein trafficking in Sertoli cells
Fri Oct 15 00:00:00 EDT 2010
The second extracellular loop dictates Occludin-mediated HCV entry.
Virology
Liu S,Kuo W,Yang W,Liu W,Gibson GA,Dorko K,Watkins SC,Strom SC,Wang T
71-1500 was used in immunocytochemistry and western blot to investigate occludin-mediated hepatitis C virus entry
Wed Nov 10 00:00:00 EST 2010
Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Cui W,Li LX,Sun CM,Wen Y,Zhou Y,Dong YL,Liu P
71-1500 was used in Western Blotting to study, using Caco-2 cells as an in vitro intestinal epithelial model, the mechanisms by which TNF-α causes elevation of intestinal epithelial permeability.
Thu Apr 01 00:00:00 EDT 2010
Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1.
The Journal of biological chemistry
Fang X,Neyrinck AP,Matthay MA,Lee JW
Fri Aug 20 00:00:00 EDT 2010
Novel snail1 target proteins in human colon cancer identified by proteomic analysis.
PloS one
Larriba MJ,Casado-Vela J,Pendás-Franco N,Peña R,García de Herreros A,Berciano MT,Lafarga M,Casal JI,Muñoz A
71-1500 was used in western blot to perform a proteomic study of Snail1-regulated events during epithelial-to-mesenchymal transition
Tue Apr 20 00:00:00 EDT 2010
A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells.
Nature protocols
Sonoda S,Spee C,Barron E,Ryan SJ,Kannan R,Hinton DR
71-1500 was used in immunocytochemistry to describe an in vitro protocol for the differentiation of human retinal pigment epithelial cells into a highly polarized and functional monolayer
Tue Jun 30 00:00:00 EDT 2009
Redox-sensitivity of the dimerization of occludin.
Cellular and molecular life sciences : CMLS
Walter JK,Castro V,Voss M,Gast K,Rueckert C,Piontek J,Blasig IE
71-1500 was used in western blot to test if occludin self-association is redox-sensitive
Sun Nov 01 00:00:00 EDT 2009
Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?
The international journal of biochemistry & cell biology
Li MW,Mruk DD,Lee WM,Cheng CY
71-1500 was used in immunocytochemistry and western blot to examine the effects of bisphenol A on the reproductive tract of male rats
Sun Nov 01 00:00:00 EDT 2009
Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier.
The international journal of biochemistry & cell biology
Su L,Cheng CY,Mruk DD
71-1500 was used in immunocytochemistry, immunoprecipitation, and western blot to determine the role of P-glycoprotein in the blood-testis barrier
Tue Dec 01 00:00:00 EST 2009
Anti-inflammatory and antioxidant effects of SERPINA3K in the retina.
Investigative ophthalmology & visual science
Zhang B,Hu Y,Ma JX
Sat Aug 01 00:00:00 EDT 2009
Expression of tight-junction proteins in the inflamed and clinically uninvolved skin in patients with venous leg ulcers.
Clinical and experimental dermatology
Zorko MS,Veranic P,Leskovec NK,Pavlović MD,Lunder T
71-1500 was used in immunohistochemistry - frozen section to examine tight junction protein expression in venous leg ulcers
Tue Dec 01 00:00:00 EST 2009
The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression.
Toxicology and applied pharmacology
Pinton P,Nougayrède JP,Del Rio JC,Moreno C,Marin DE,Ferrier L,Bracarense AP,Kolf-Clauw M,Oswald IP
71-1500 was used in immunocytochemistry to examine the effects of deoxynivalenol on the intestinal epithelium
Fri May 15 00:00:00 EDT 2009
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.
Molecular biology of the cell
Abouhamed M,Grobe K,San IV,Thelen S,Honnert U,Balda MS,Matter K,Bähler M
Tue Dec 01 00:00:00 EST 2009
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.
Molecular biology of the cell
Abouhamed M,Grobe K,San IV,Thelen S,Honnert U,Balda MS,Matter K,Bähler M
Tue Dec 01 00:00:00 EST 2009
TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesis.
Developmental biology
Xia W,Wong EW,Mruk DD,Cheng CY
71-1500 was used in immunocytochemistry and western blot to study factors that contribute to the disruption of the blood-testis barrier
Sun Mar 01 00:00:00 EST 2009
Zonula occludens-1, occludin, and E-cadherin protein expression in biliary tract cancers.
Pathology oncology research : POR
Németh Z,Szász AM,Somorácz A,Tátrai P,Németh J,Gyorffy H,Szíjártó A,Kupcsulik P,Kiss A,Schaff Z
71-1500 was used in immunohistochemistry - paraffin section to examine ZO-1, occludin, and E-cadherin expression in normal and neoplastic biliary tract samples
Tue Sep 01 00:00:00 EDT 2009
Diabetic rat testes: morphological and functional alterations.
Andrologia
Ricci G,Catizone A,Esposito R,Pisanti FA,Vietri MT,Galdieri M
71-1500 was used in immunohistochemistry - paraffin section to test if age affects diabetes-induce testicular tissue changes
Tue Dec 01 00:00:00 EST 2009
Expression of occludin in testis and epididymis of wild rabbits, Lepus sinensis coreanus.
Reproduction in domestic animals = Zuchthygiene
Yoon SI,Park CJ,Nah WH,Gye MC
71-1500 was used in immunohistochemistry - paraffin section and western blot to study tight junction protein expression using Lepus sinensis coreanus
Thu Oct 01 00:00:00 EDT 2009
Establishment of a standardized post-embedding method for immunoelectron microscopy by applying heat-induced antigen retrieval.
Journal of electron microscopy
Yamashita S,Katsumata O,Okada Y
71-1500 was used in immunohistochemistry to report a new standardized method for post-embedding immunoelectron microscopy
Sat Aug 01 00:00:00 EDT 2009
Effects of formaldehyde inhalation on the junctional proteins of nasal respiratory mucosa of rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
Arican RY,Sahin Z,Ustunel I,Sarikcioglu L,Ozdem S,Oguz N
71-1500 was used in immunohistochemistry - paraffin section to determine the protein changes in the junctional complex of nasal mucosa of Wistar rats exposed to formaldehyde inhalation
Wed Jul 01 00:00:00 EDT 2009
Tight junctions in Hailey-Hailey and Darier's diseases.
Dermatology reports
Raiko L,Leinonen P,Hägg PM,Peltonen J,Oikarinen A,Peltonen S
71-1500 was used in immunohistochemistry (frozen) to study the expression and dynamics of the tight junction proteins during the disruption of desmosomes in Hailey-Hailey disease and Darier's disease lesions.
Mon Nov 16 00:00:00 EST 2009
Toxic effects of brake wear particles on epithelial lung cells in vitro.
Particle and fibre toxicology
Gasser M,Riediker M,Mueller L,Perrenoud A,Blank F,Gehr P,Rothen-Rutishauser B
71-1500 was used in immunocytochemistry to report the toxic effects of brake wear particles on epithelial lung cells in vitro
Fri Nov 20 00:00:00 EST 2009
An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Yan HH,Mruk DD,Wong EW,Lee WM,Cheng CY
71-1500 was used in immunocytochemistry to investigate the role of beta1-integrin in hemidesmosome
Tue Jul 01 00:00:00 EDT 2008
Functional live cell imaging of the pulmonary neuroepithelial body microenvironment.
American journal of respiratory cell and molecular biology
De Proost I,Pintelon I,Brouns I,Kroese AB,Riccardi D,Kemp PJ,Timmermans JP,Adriaensen D
71-1500 was used in immunocytochemistry to develop an ex vivo mouse lung vibratome slice model for confocal live cell imaging of neuroepithelial bodies and surrounding epithelial cells
Fri Aug 01 00:00:00 EDT 2008
Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node.
European journal of immunology
Pfeiffer F,Kumar V,Butz S,Vestweber D,Imhof BA,Stein JV,Engelhardt B
71-1500 was used in immunohistochemistry to examine the architecture of cellular junctions present in blood and lymphatic vessel endothelium in peripheral lymph nodes
Fri Aug 01 00:00:00 EDT 2008
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yan HH,Mruk DD,Lee WM,Cheng CY
Sun Jun 01 00:00:00 EDT 2008
Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system.
American journal of physiology. Gastrointestinal and liver physiology
Lussier CR,Babeu JP,Auclair BA,Perreault N,Boudreau F
71-1500 was used in western blot to develop and characterize a mesenchymal-epithelial coculture system to identify transcriptional regulators of intestinal epithelial cell differentiation
Fri Feb 01 00:00:00 EST 2008
Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line.
Experimental cell research
Aono S,Hirai Y
71-1500 was used in western blot to suggest that aPKC regulates tight junction formation through the phosphorylation of claudin-4
Sat Nov 01 00:00:00 EDT 2008
Regulation of testicular tight junctions by gonadotrophins in the adult Djungarian hamster in vivo.
Reproduction (Cambridge, England)
Tarulli GA,Meachem SJ,Schlatt S,Stanton PG
71-1500 was used in Immunohistochemistry-immunofluorescence to assess the effect of gonadotrophin suppression and FSH replacement on testicular tight junction dynamics and blood-testis barrier organisation in vivo.
Sun Jun 01 00:00:00 EDT 2008
Expression and localisation of apical junctional complex proteins in lens epithelial cells.
Experimental eye research
Sugiyama Y,Prescott AR,Tholozan FM,Ohno S,Quinlan RA
71-1500 was used in immunohistochemistry and western blot to determine the composition of the apical junctional complex present in lens epithelial cells
Tue Jul 01 00:00:00 EDT 2008
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Developmental biology
Marose TD,Merkel CE,McMahon AP,Carroll TJ
71-1500 was used in immunohistochemistry - frozen section to describe a role for beta-catenin in kidney development
Fri Feb 01 00:00:00 EST 2008
Griffonia simplicifolia isolectin B4 identifies a specific subpopulation of angiogenic blood vessels following contusive spinal cord injury in the adult mouse.
The Journal of comparative neurology
Benton RL,Maddie MA,Minnillo DR,Hagg T,Whittemore SR
Sat Mar 01 00:00:00 EST 2008
Different expression of occludin and ZO-1 in primary and metastatic liver tumors.
Pathology oncology research : POR
Orbán E,Szabó E,Lotz G,Kupcsulik P,Páska C,Schaff Z,Kiss A
71-1500 was used in immunohistochemistry - paraffin section to discover differences between occludin and ZO-1 expression in normal liver samples, HCCs, and colorectal liver metastases
Mon Sep 01 00:00:00 EDT 2008
Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression.
Molecular membrane biology
Paschoud S,Citi S
71-1500 was used in immunocytochemistry and western blot to study the effects of cingulin overexpression
Tue Jan 01 00:00:00 EST 2008
Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
Nature immunology
Hamazaki Y,Fujita H,Kobayashi T,Choi Y,Scott HS,Matsumoto M,Minato N
71-1500 was used in immunohistochemistry - frozen section to examine the origin and development of Aire positive medullary thymic epithelial cells
Thu Mar 01 00:00:00 EST 2007
Abnormal development of urogenital organs in Dlgh1-deficient mice.
Development (Cambridge, England)
Iizuka-Kogo A,Ishidao T,Akiyama T,Senda T
71-1500 was used in immunohistochemistry to characterize Dlgh1 knockout mice
Tue May 01 00:00:00 EDT 2007
Differentiation potential of urothelium from patients with benign bladder dysfunction.
BJU international
Southgate J,Varley CL,Garthwaite MA,Hinley J,Marsh F,Stahlschmidt J,Trejdosiewicz LK,Eardley I
71-1500 was used in immunocytochemistry and immunohistochemistry - paraffin section to ask if urothelial differentiation failure contributes to the aetiopathology of interstitial cystitis
Fri Jun 01 00:00:00 EDT 2007
Tight and adherens junctions in the ovine uterus: differential regulation by pregnancy and progesterone.
Endocrinology
Satterfield MC,Dunlap KA,Hayashi K,Burghardt RC,Spencer TE,Bazer FW
71-1500 was used in Immunohistochemistry to identify changes in junctional complexes in the ovine endometrium that regulate paracellular trafficking of water, ions, and other molecules, and the secretory capacity of the uterine epithelia.
Wed Aug 01 00:00:00 EDT 2007
Regulation of tight junction proteins occludin and claudin 5 in the primate ovary during the ovulatory cycle and after inhibition of vascular endothelial growth factor.
Molecular human reproduction
Rodewald M,Herr D,Fraser HM,Hack G,Kreienberg R,Wulff C
71-1500 was used in immunohistochemistry - paraffin section to analyze tight junction protein expression during follicular and luteal development in the primate ovary and after inhibition of vascular endothelial growth factor
Thu Nov 01 00:00:00 EDT 2007
Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis.
Neuroscience
Morgan L,Shah B,Rivers LE,Barden L,Groom AJ,Chung R,Higazi D,Desmond H,Smith T,Staddon JM
71-1500 was used in immunohistochemistry - frozen section, immunoprecipitation, and western blot to analyze lumbar spinal cord proteins present in naive and experimental autoimmune encephalomyelitis rats
Fri Jul 13 00:00:00 EDT 2007
Estrogen modulation of epithelial permeability in cervical-vaginal cells of premenopausal and postmenopausal women.
Menopause (New York, N.Y.)
Gorodeski GI
71-1500 was used in western blot to discuss how menopause affects estrogen regulation of epithelial permeability
Fri Feb 01 00:00:00 EST 2008
Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer.
Pathology international
Atsumi T,Kato K,Uno K,Iijima K,Koike T,Imatani A,Ohara S,Shimosegawa T
71-1500 was used in western blot to find phospho-p38 MAPK level significantly increases in poorly differentiated gastric cancers compared to differentiated cancers and normal gastric mucosa
Mon Oct 01 00:00:00 EDT 2007
Heat-induced antigen retrieval: mechanisms and application to histochemistry.
Progress in histochemistry and cytochemistry
Yamashita S
71-1500 was used in immunohistochemistry - frozen section to review mechanisms and applications of heat-induced antigen retrieval
Tue Mar 13 00:00:00 EDT 2007
Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.
Cancer research
Oku N,Sasabe E,Ueta E,Yamamoto T,Osaki T
71-1500 was used in western blot to test if claudin-1 regulates invasion of oral squamous cell carcinoma cells
Mon May 15 00:00:00 EDT 2006
CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier: a potential mechanism of HIV-CNS invasion and NeuroAIDS.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Eugenin EA,Osiecki K,Lopez L,Goldstein H,Calderon TM,Berman JW
Wed Jan 25 00:00:00 EST 2006
Cell junctional proteins in the human corpus luteum: changes during the normal cycle and after HCG treatment.
Human reproduction (Oxford, England)
Groten T,Fraser HM,Duncan WC,Konrad R,Kreienberg R,Wulff C
71-1500 was used in Immunohistochemistry to investigate the occurrence, distribution and hormonal control of the adherens junction protein vascular endothelial cadherin and the tight junction proteins occludin and claudin in the human corpus luteum.
Fri Dec 01 00:00:00 EST 2006
Tight junction proteins and perineurial cells in neurofibromas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Pummi KP,Aho HJ,Laato MK,Peltonen JT,Peltonen SA
71-1500 was used in immunohistochemistry - frozen section to determine the distribution and role of perineurial cells in neurofibromas
Sun Jan 01 00:00:00 EST 2006
Endothelia of term human placentae display diminished expression of tight junction proteins during preeclampsia.
Cell and tissue research
Liévano S,Alarcón L,Chávez-Munguía B,González-Mariscal L
71-1500 was used in immunohistochemistry - frozen section and western blot to examine the molecular composition of the tight junction present in human term placenta from normal women and from those with preeclampsia
Thu Jun 01 00:00:00 EDT 2006
Epithelial barrier characteristics and expression of cell adhesion molecules in proximal tubule-derived cell lines commonly used for in vitro toxicity studies.
Toxicology in vitro : an international journal published in association with BIBRA
Prozialeck WC,Edwards JR,Lamar PC,Smith CS
71-1500 was used in immunocytochemistry to characterize cell lines that mimic the characteristics of the proximal tubule
Fri Sep 01 00:00:00 EDT 2006
An optimized in vitro model of the respiratory tract wall to study particle cell interactions.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine
Blank F,Rothen-Rutishauser BM,Schurch S,Gehr P
71-1500 was used in immunocytochemistry to develop an in vitro model of the respiratory tract wall
Tue Jan 16 00:00:00 EST 2007
A three-dimensional cellular model of the human respiratory tract to study the interaction with particles.
American journal of respiratory cell and molecular biology
Rothen-Rutishauser BM,Kiama SG,Gehr P
71-1500 was used in immunocytochemistry to develop and characterize a triple co-culture model of the human airway barrier
Fri Apr 01 00:00:00 EST 2005
Drebrin, an actin-binding, cell-type characteristic protein: induction and localization in epithelial skin tumors and cultured keratinocytes.
The Journal of investigative dermatology
Peitsch WK,Hofmann I,Bulkescher J,Hergt M,Spring H,Bleyl U,Goerdt S,Franke WW
Sat Oct 01 00:00:00 EDT 2005
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.
American journal of physiology. Cell physiology
Yu AS,McCarthy KM,Francis SA,McCormack JM,Lai J,Rogers RA,Lynch RD,Schneeberger EE
Wed Jun 01 00:00:00 EDT 2005
Changes of cell adhesion and extracellular matrix (ECM) components in cervical intraepithelial neoplasia.
Pathology oncology research : POR
Sobel G,Szabó I,Páska C,Kiss A,Kovalszky I,Kádár A,Paulin F,Schaff Z
71-1500 was used in immunohistochemistry - paraffin section to observe the expression of occludin and syndecan-1 in the early phases of cervical carcinogenesis
Tue Aug 09 00:00:00 EDT 2005
Urothelial injuries and the early wound healing response: tight junctions and urothelial cytodifferentiation.
Histochemistry and cell biology
Kreft ME,Sterle M,Veranic P,Jezernik K
71-1500 was used in immunohistochemistry to examine the early response of the urothelium after superficial and full-thickness injuries
Wed Jun 01 00:00:00 EDT 2005
Establishment and characterization of primary and subsequent subcultures of normal mouse urothelial cells.
Folia biologica
Kreft ME,Hudoklin S,Sterle M
71-1500 was used in immunocytochemistry to report a reliable technique for the harvest, cultivation and expansion of monoculture of NMU and characterize the isolated cells
Fri Jan 13 00:00:00 EST 2006
Channel-forming peptide modulates transepithelial electrical conductance and solute permeability.
American journal of physiology. Cell physiology
Broughman JR,Brandt RM,Hastings C,Iwamoto T,Tomich JM,Schultz BD
71-1500 was used in immunocytochemistry to elucidate how NC-1059 treatment alters tight junction proteins
Tue Jun 01 00:00:00 EDT 2004
Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression.
Journal of cell science
Guillemot L,Hammar E,Kaister C,Ritz J,Caille D,Jond L,Bauer C,Meda P,Citi S
71-1500 was used in western blot to test if lack of junctional cingulin affects tight-junction organization and function
Fri Oct 15 00:00:00 EDT 2004
The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells.
Journal of cell science
Nava P,López S,Arias CF,Islas S,González-Mariscal L
71-1500 was used in immunocytochemistry and western blot to test if the rotavirus outer capsid proteins are capable of opening the paracellular space sealed by the tight junctions
Mon Nov 01 00:00:00 EST 2004
Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.
Investigative ophthalmology & visual science
Bailey TA,Kanuga N,Romero IA,Greenwood J,Luthert PJ,Cheetham ME
71-1500 was used in immunocytochemistry to examine the effect of oxidative stress on stress protein induction and junctional integrity
Sun Feb 01 00:00:00 EST 2004
The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells.
Experimental cell research
Betanzos A,Huerta M,Lopez-Bayghen E,Azuara E,Amerena J,González-Mariscal L
71-1500 was used in immunocytochemistry to examine the role of nuclear ZO-2
Thu Jan 01 00:00:00 EST 2004
Kidney ischemia-reperfusion regulates expression and distribution of tubulin subunits, beta-actin and rho GTPases in proximal tubules.
Archives of biochemistry and biophysics
Caron A,Desrosiers RR,Béliveau R
71-1500 was used in western blot to use a reversible unilateral renal ischemia-reperfusion model to study the expression and distribution of cytoskeletal components and Rho GTPases in proximal tubule fractions
Mon Nov 01 00:00:00 EST 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 EDT 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 EDT 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 EDT 2004
Expression of occludin in canine testis and epididymis.
Reproduction in domestic animals = Zuchthygiene
Gye MC
71-1500 was used in immunohistochemistry - paraffin section and western blot to use canine testis and epididymis to study occludin expression
Sun Feb 01 00:00:00 EST 2004
Immunohistological distribution of the tight junction components ZO-1 and occludin in regenerating human epidermis.
The British journal of dermatology
Malminen M,Koivukangas V,Peltonen J,Karvonen SL,Oikarinen A,Peltonen S
71-1500 was used in immunohistochemistry to discuss methods to study tight junctions.
Fri Aug 01 00:00:00 EDT 2003
SRC-induced disintegration of adherens junctions of madin-darby canine kidney cells is dependent on endocytosis of cadherin and antagonized by Tiam-1.
Laboratory investigation; a journal of technical methods and pathology
Palovuori R,Sormunen R,Eskelinen S
71-1500 was used in immunoprecipitation to investigate the effects of Src tyrosine kinase activation in temperature sensitive-Src-transformed Madin-Darby canine kidney cells.
Mon Dec 01 00:00:00 EST 2003
Age-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1).
Mechanisms of ageing and development
Mooradian AD,Haas MJ,Chehade JM
71-1500 was used in western blot to study tight junction proteins in the cerebrum of aging rats
Sat Feb 01 00:00:00 EST 2003
Rab8B GTPase and junction dynamics in the testis.
Endocrinology
Lau AS,Mruk DD
71-1500 was used in western blot to elucidate the role of Rab8B in germ cell movement.
Tue Apr 01 00:00:00 EST 2003
The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis.
Endocrinology
Siu MK,Lee WM,Cheng CY
71-1500 was used in western blot to examine the role of the extracellular matrix in Sertoli cell tight junction dynamics.
Wed Jan 01 00:00:00 EST 2003
Pro-inflammatory cytokines modulate matrix metalloproteinase secretion and organic anion transport at the blood-cerebrospinal fluid barrier.
Journal of neuropathology and experimental neurology
Strazielle N,Khuth ST,Murat A,Chalon A,Giraudon P,Belin MF,Ghersi-Egea JF
71-1500 was used in Immunocytochemistry to demonstrate that both fourth and lateral ventricle CPs are a source of pro- and active MMP-2 and MMP-9 in the brain.
Mon Dec 01 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B.
The Journal of biological chemistry
Traweger A,Fuchs R,Krizbai IA,Weiger TM,Bauer HC,Bauer H
Fri Jan 24 00:00:00 EST 2003
The renal segmental distribution of claudins changes with development.
Kidney international
Reyes JL,Lamas M,Martin D,del Carmen Namorado M,Islas S,Luna J,Tauc M,González-Mariscal L
71-1500 was used in immunohistochemistry - frozen section and western blot to examine the differential expression of occludin and several claudins in isolated renal tubules from newborn and adult rabbits.
Thu Aug 01 00:00:00 EDT 2002
Antigenic and ultrastructural markers associated with urothelial cytodifferentiation in primary explant outgrowths of mouse bladder.
Cell biology international
Kreft ME,Romih R,Sterle M
71-1500 was used in immunocytochemistry to establish and characterize an in vitro culture model of whole mouse urothelial tissue
Mon May 20 00:00:00 EDT 2002
E-Cadherin and tight junctions between epithelial cells of different animal species.
Pflugers Archiv : European journal of physiology
Contreras RG,Shoshani L,Flores-Maldonado C,Lázaro A,Monroy AO,Roldán ML,Fiorentino R,Cereijido M
71-1500 was used in immunocytochemistry to investigate tight junctions and E-cadherin in heterotypic borders.
Mon Jul 01 00:00:00 EDT 2002
Diabetes-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1) expression.
Neurochemical research
Chehade JM,Haas MJ,Mooradian AD
71-1500 was used in western blot to test if diabetes alters tight junction proteins
Fri Mar 01 00:00:00 EST 2002
2,3-butanedione monoxime (BDM), a potent inhibitor of actin-myosin interaction, induces ion and fluid transport in MDCK monolayers.
Journal of muscle research and cell motility
Castillo AM,Reyes JL,Sánchez E,Mondragón R,Meza I
71-1500 was used in immunocytochemistry to investigate the role of myosin in vectorial transport
Fri May 30 00:00:00 EDT 2003
[Malignant fibrous histiocytoma of the eyelid].
Journal francais d'ophtalmologie
Rossi P,Ducasse A,Pluot M,Brugniart C,Gotzamanis A,Jouhaud F
Sun Dec 01 00:00:00 EST 2002
JEAP, a novel component of tight junctions in exocrine cells.
The Journal of biological chemistry
Nishimura M,Kakizaki M,Ono Y,Morimoto K,Takeuchi M,Inoue Y,Imai T,Takai Y
Fri Feb 15 00:00:00 EST 2002
Applications of epithelial cell culture in studies of drug transport.
Methods in molecular biology (Clifton, N.J.)
Tavelin S,Gråsjö J,Taipalensuu J,Ocklind G,Artursson P
71-1500 was used in immunocytochemistry to review applications of epithelial cell culture in studies of drug transport
Tue Nov 12 00:00:00 EST 2002
Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells.
The Journal of cell biology
Yeaman C,Grindstaff KK,Wright JR,Nelson WJ
Mon Nov 12 00:00:00 EST 2001
Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes.
The Journal of investigative dermatology
Pummi K,Malminen M,Aho H,Karvonen SL,Peltonen J,Peltonen S
71-1500 was used in western blot to test if tight junction antigens are present in adult and developing human epidermis.
Thu Nov 01 00:00:00 EST 2001
Tight junction proteins ZO-1, ZO-2, and occludin along isolated renal tubules.
Kidney international
Gonzalez-Mariscal L,Namorado MC,Martin D,Luna J,Alarcon L,Islas S,Valencia L,Muriel P,Ponce L,Reyes JL
71-1500 was used in immunohistochemistry (frozen) to examine the differential expression of three tight junction proteins, ZO-1, ZO-2, and occludin, along isolated rabbit renal tubules.
Thu Jun 01 00:00:00 EDT 2000
Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Lawlor P,Marcotti W,Rivolta MN,Kros CJ,Holley MC
71-1500 was used in immunocytochemistry to study hair cell development using a new cell line.
Mon Nov 01 00:00:00 EST 1999
Relationship between Na(+),K(+)-ATPase and cell attachment.
Journal of cell science
Contreras RG,Shoshani L,Flores-Maldonado C,Lázaro A,Cereijido M
71-1500 was used in immunocytochemistry to study the effect of ouabain treatment on cell attachment.
Wed Dec 01 00:00:00 EST 1999
Tight junctions and the experimental modifications of lipid content.
The Journal of membrane biology
Calderón V,Lázaro A,Contreras RG,Shoshani L,Flores-Maldonado C,González-Mariscal L,Zampighi G,Cereijido M
71-1500 was used in immunocytochemistry to show that changing the total composition of phospholipids, sphingolipids, cholesterol, and the content of fatty acids does not alter TER nor the structure of the strands present at tight junctions.
Wed Jul 01 00:00:00 EDT 1998
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.
The Journal of cell biology
Stevenson BR,Siliciano JD,Mooseker MS,Goodenough DA
Mon Sep 01 00:00:00 EDT 1986
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.
The Journal of cell biology
Stevenson BR,Siliciano JD,Mooseker MS,Goodenough DA
Mon Sep 01 00:00:00 EDT 1986
