Product References
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
World neurosurgery
Yidian W,Jihe K,Xudong G,Daxue Z,Mingqiang L,Xuewen K
Tue Aug 01 00:00:00 EDT 2023
Integrated metabolomics and phosphoproteomics reveal the protective role of exosomes from human umbilical cord mesenchymal stem cells in naturally aging mouse livers.
Experimental cell research
Ling M,Tang C,Yang X,Yu N,Song Y,Ding W,Sun Y,Yan R,Wang S,Li X,Gao H,Zhang Z,Xing Y
Thu Jun 01 00:00:00 EDT 2023
A stress-induced cilium-to-PML-NB route drives senescence initiation.
Nature communications
Ma X,Zhang Y,Zhang Y,Zhang X,Huang Y,He K,Chen C,Hao J,Zhao D,LeBrasseur NK,Kirkland JL,Chini EN,Wei Q,Ling K,Hu J
Mon Apr 03 00:00:00 EDT 2023
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.
Aging and disease
Lin X,Xiang QY,Li S,Song WL,Wang YJ,Ni YQ,Zhao Y,Li C,Wang Y,Li HH,Liang Z,Zhan JK,Liu YS
Wed Feb 01 00:00:00 EST 2023
P16INK4a Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Oxidative medicine and cellular longevity
Sun J,Zhou L,Yang T,Deng B,Bao Y,Gu L,Wang H,Wang L
Tue Mar 07 00:00:00 EST 2023
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
European journal of pharmacology
Wu Y,Wu Y,Yu J,Zhang Y,Li Y,Fu R,Sun Y,Zhao K,Xiao Q
Sun Jan 15 00:00:00 EST 2023
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Toxicology
Li M,Li T,Yin J,Xie C,Zhu J
Sun Jan 15 00:00:00 EST 2023
Decrease in the expression of muscle-specific miRNAs, miR-133a and miR-1, in myoblasts with replicative senescence.
PloS one
Shintani-Ishida K,Tsurumi R,Ikegaya H
Wed Aug 09 00:00:00 EDT 2023
Acceleration of melanocyte senescence by the proinflammatory cytokines IFNγ and TNFα impairs the repigmentation response of vitiligo patients to narrowband ultraviolet B (NBUVB) phototherapy.
Mechanisms of ageing and development
Dong BQ,Liao ZK,Le Y,Jiang S,Luo LF,Miao F,Le Poole IC,Lei TC
Sat Apr 01 00:00:00 EDT 2023
Acceleration of melanocyte senescence by the proinflammatory cytokines IFNγ and TNFα impairs the repigmentation response of vitiligo patients to narrowband ultraviolet B (NBUVB) phototherapy.
Mechanisms of ageing and development
Dong BQ,Liao ZK,Le Y,Jiang S,Luo LF,Miao F,Le Poole IC,Lei TC
Sat Apr 01 00:00:00 EDT 2023
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Cell biology and toxicology
Jiang Y,Zhou Y,Xu W,Wang X,Jin H,Bao X,Lu C
Thu Jun 01 00:00:00 EDT 2023
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Cell biology and toxicology
Jiang Y,Zhou Y,Xu W,Wang X,Jin H,Bao X,Lu C
Thu Jun 01 00:00:00 EDT 2023
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Cell biology and toxicology
Jiang Y,Zhou Y,Xu W,Wang X,Jin H,Bao X,Lu C
Thu Jun 01 00:00:00 EDT 2023
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Cell biology and toxicology
Jiang Y,Zhou Y,Xu W,Wang X,Jin H,Bao X,Lu C
Thu Jun 01 00:00:00 EDT 2023
miR-656-3p inhibits melanomas in vitro and in vivo by inducing senescence via inhibiting LMNB2.
Journal of cancer research and clinical oncology
Sun J,Lui K,Pang Q,Xu M,Zhao H,Shao J,Yu Y,Chu X,Liang Y,Xu J,Shen Z
Fri Sep 01 00:00:00 EDT 2023
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Journal of ethnopharmacology
Liu J,Yang Y,He Y,Feng C,Ou H,Yang J,Chen Y,You F,Shao B,Bao J,Guan X,Chen F,Zhao P
Sat Mar 25 00:00:00 EDT 2023
Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology.
International journal of molecular sciences
Shang Z,Fan M,Zhang J,Wang Z,Jiang S,Li W
Thu May 04 00:00:00 EDT 2023
Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology.
International journal of molecular sciences
Shang Z,Fan M,Zhang J,Wang Z,Jiang S,Li W
Thu May 04 00:00:00 EDT 2023
Involvement of lncRNA TUG1 in HIV-1 Tat-Induced Astrocyte Senescence.
International journal of molecular sciences
Pillai PP,Kannan M,Sil S,Singh S,Thangaraj A,Chivero ET,Dagur RS,Tripathi A,Hu G,Periyasamy P,Buch S
Wed Feb 22 00:00:00 EST 2023
CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Cell reports
Zhou Z,Zhang H,Tao Y,Jie H,Zhao J,Zang J,Li H,Wang Y,Wang T,Zhao H,Li Y,Guo C,Zhu F,Mao H,Zhang L,Liu F,Wang Q
Tue May 30 00:00:00 EDT 2023
CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Cell reports
Zhou Z,Zhang H,Tao Y,Jie H,Zhao J,Zang J,Li H,Wang Y,Wang T,Zhao H,Li Y,Guo C,Zhu F,Mao H,Zhang L,Liu F,Wang Q
Tue May 30 00:00:00 EDT 2023
CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Cell reports
Zhou Z,Zhang H,Tao Y,Jie H,Zhao J,Zang J,Li H,Wang Y,Wang T,Zhao H,Li Y,Guo C,Zhu F,Mao H,Zhang L,Liu F,Wang Q
Tue May 30 00:00:00 EDT 2023
CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Cell reports
Zhou Z,Zhang H,Tao Y,Jie H,Zhao J,Zang J,Li H,Wang Y,Wang T,Zhao H,Li Y,Guo C,Zhu F,Mao H,Zhang L,Liu F,Wang Q
Tue May 30 00:00:00 EDT 2023
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Molecular and cellular biochemistry
Hu Z,Zhang Y,Chen J,Luo M,Wang N,Xiao Y,He Q
Tue Aug 01 00:00:00 EDT 2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
International journal of molecular sciences
Chen H,Tu M,Liu S,Wen Y,Chen L
Wed Jan 25 00:00:00 EST 2023
Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells.
Cancers
Gupta A,Carnazza M,Jones M,Darzynkiewicz Z,Halicka D,O'Connell T,Zhao H,Dadafarin S,Shin E,Schwarcz MD,Moscatello A,Tiwari RK,Geliebter J
Fri Apr 07 00:00:00 EDT 2023
Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells.
Cancers
Gupta A,Carnazza M,Jones M,Darzynkiewicz Z,Halicka D,O'Connell T,Zhao H,Dadafarin S,Shin E,Schwarcz MD,Moscatello A,Tiwari RK,Geliebter J
Fri Apr 07 00:00:00 EDT 2023
Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells.
Cancers
Gupta A,Carnazza M,Jones M,Darzynkiewicz Z,Halicka D,O'Connell T,Zhao H,Dadafarin S,Shin E,Schwarcz MD,Moscatello A,Tiwari RK,Geliebter J
Fri Apr 07 00:00:00 EDT 2023
IL-17A promotes endothelial cell senescence by up-regulating the expression of FTO through activating JNK signal pathway.
Biogerontology
Li N,Luo R,Zhang W,Wu Y,Hu C,Liu M,Jiang D,Jiang Z,Zhao X,Wang Y,Li Q
Wed Feb 01 00:00:00 EST 2023
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Cell transplantation
Li H,Ren J,Cui H,Wang D,Zhao R,Liu X,Tian S,Wang J,Zhang J,Li P,Thorne RF,Duan S
Mon Jun 05 00:00:00 EDT 2023
1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice.
International journal of biological sciences
Chen J,Zhang J,Li J,Qin R,Lu N,Goltzman D,Miao D,Yang R
Thu Feb 09 00:00:00 EST 2023
Serum response factor activates peroxidasin transcription to block senescence of hepatic stellate cells.
Life sciences
Guo Y,Zhou A,Zhang Y,Chen Y,Chen Y,Gao Y,Miao X
Fri Sep 01 00:00:00 EDT 2023
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.
Journal of physiology and biochemistry
Li S,Ni Y,Li C,Xiang Q,Zhao Y,Xu H,Huang W,Wang Y,Wang Y,Zhan J,Liu Y
Wed Feb 01 00:00:00 EST 2023
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Cell proliferation
Tang Q,Markby GR,MacNair AJ,Tang K,Tkacz M,Parys M,Phadwal K,MacRae VE,Corcoran BM
Thu Jun 01 00:00:00 EDT 2023
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
Redox biology
Ma L,Li K,Wei W,Zhou J,Li Z,Zhang T,Wangsun Y,Tian F,Dong Q,Zhang H,Xing W
Thu Jun 01 00:00:00 EDT 2023
[Research of epigallocatechin gallate in delaying chondrocyte senescence].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Luo C,Zhou W,Zhang H,Zhu J,Chen L,Gu Y
Wed Mar 15 00:00:00 EDT 2023
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
iScience
Peng Z,Tan X,Xie L,Li Z,Zhou S,Li Y
Fri Jan 20 00:00:00 EST 2023
PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis.
Stem cell reviews and reports
Wang Y,Sui Y,Niu Y,Liu D,Xu Q,Liu F,Zuo K,Liu M,Sun W,Wang Z,Liu Z,Zou F,Shi J,Liu X,Liu J
Wed Feb 01 00:00:00 EST 2023
The cell senescence regulator p16 is a promising cancer prognostic and immune check-point inhibitor (ICI) therapy biomarker.
Aging
Tu Z,Wang X,Cai H,Sheng Y,Wu L,Huang K,Zhu X
Thu Mar 23 00:00:00 EDT 2023
The cell senescence regulator p16 is a promising cancer prognostic and immune check-point inhibitor (ICI) therapy biomarker.
Aging
Tu Z,Wang X,Cai H,Sheng Y,Wu L,Huang K,Zhu X
Thu Mar 23 00:00:00 EDT 2023
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Journal of ethnopharmacology
Duan J,Li Z,Liu E,Long H,Chen L,Yang S
Wed Nov 15 00:00:00 EST 2023
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
BMC medicine
Gautheron J,Lima L,Akinci B,Zammouri J,Auclair M,Ucar SK,Ozen S,Altay C,Bax BE,Nemazanyy I,Lenoir V,Prip-Buus C,Acquaviva-Bourdain C,Lascols O,Fève B,Vigouroux C,Noel E,Jéru I
Mon Mar 28 00:00:00 EDT 2022
A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis.
International journal of molecular sciences
Meang MK,Kim S,Kim IH,Kim HS,Youn BS
Mon Jun 20 00:00:00 EDT 2022
A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis.
International journal of molecular sciences
Meang MK,Kim S,Kim IH,Kim HS,Youn BS
Mon Jun 20 00:00:00 EDT 2022
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
PloS one
Pogacar Z,Johnson JL,Krenning L,De Conti G,Jochems F,Lieftink C,Velds A,Wardak L,Groot K,Schepers A,Wang L,Song JY,van de Ven M,van Tellingen O,Medema RH,Beijersbergen RL,Bernards R,Leite de Oliveira R
Thu Sep 08 00:00:00 EDT 2022
Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Gao L,Yang WY,Qi H,Sun CJ,Qin XM,Du GH
Sun May 01 00:00:00 EDT 2022
Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis.
Journal of cell science
Alves LS,Marques ARA,Padrão N,Carvalho FA,Ramalho J,Lopes CS,Soares MIL,Futter CE,Pinho E Melo TMVD,Santos NC,Vieira OV
Tue Mar 01 00:00:00 EST 2022
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis.
Nature communications
Kang D,Lee J,Jung J,Carlson BA,Chang MJ,Chang CB,Kang SB,Lee BC,Gladyshev VN,Hatfield DL,Lee BJ,Kim JH
Wed Feb 09 00:00:00 EST 2022
LncRNA LYPLAL1-AS1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional MIRLET7B inactivation.
Cell & bioscience
Yang Y,Liu S,He C,Lv T,Zeng L,Zhang F,Chen H,Zhao RC
Thu Apr 21 00:00:00 EDT 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 EDT 2022
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
Odontology
Giri S,Takada A,Paudel D,Yoshida K,Furukawa M,Kuramitsu Y,Matsushita K,Abiko Y,Furuichi Y
Sat Jan 01 00:00:00 EST 2022
Reversion of glucocorticoid-induced senescence and collagen synthesis decrease by LY294002 is mediated through p38 in skin.
International journal of biological sciences
Le QV,Wen SY,Chen CJ,Huang CY,Kuo WW
Tue Nov 29 00:00:00 EST 2022
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary.
GeroScience
Hense JD,Garcia DN,Isola JV,Alvarado-Rincón JA,Zanini BM,Prosczek JB,Stout MB,Mason JB,Walsh PT,Brieño-Enríquez MA,Schadock I,Barros CC,Masternak MM,Schneider A
Wed Jun 01 00:00:00 EDT 2022
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
BMC pulmonary medicine
Li MY,Qin YQ,Tian YG,Li KC,Oliver BG,Liu XF,Zhao P,Li JS
Tue Nov 22 00:00:00 EST 2022
Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma.
Cell death discovery
Wang F,Cheng C,Wang X,Chen F,Li H,Zhou Y,Wang Y,Hu X,Kong P,Zhang L,Cheng X,Cui Y
Fri Apr 08 00:00:00 EDT 2022
SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity.
Cell metabolism
Lee G,Kim YY,Jang H,Han JS,Nahmgoong H,Park YJ,Han SM,Cho C,Lim S,Noh JR,Oh WK,Lee CH,Kim S,Kim JB
Tue May 03 00:00:00 EDT 2022
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Disease markers
Wen Y,Li Y,Yang B,Guo X,Lin L,Liang J,Zhang K,Li X,Jiang Z,Wang Y,Li Y,Wu X,Fan X,Li F,Yuan W
Mon Nov 28 00:00:00 EST 2022
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
International immunopharmacology
Cai W,Zhang Y,Jin W,Wei S,Chen J,Zhong C,Zhong Y,Tu C,Peng H
Thu Dec 01 00:00:00 EST 2022
Loss of legumain induces premature senescence and mediates aging-related renal fibrosis.
Aging cell
Wang D,Kang L,Chen C,Guo J,Du L,Zhou D,Li G,Zhang Y,Mi X,Zhang M,Liu S,Tan X
Tue Mar 01 00:00:00 EST 2022
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
EBioMedicine
Jyothula SSK,Peters A,Liang Y,Bi W,Shivshankar P,Yau S,Garcha PS,Yuan X,Akkanti B,Collum S,Wareing N,Thandavarayan RA,Poli de Frias F,Rosas IO,Zhao B,Buja LM,Eltzschig HK,Huang HJ,Karmouty-Quintana H
Thu Dec 01 00:00:00 EST 2022
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Biochemical and biophysical research communications
Shi J,Sun J,Liu L,Shan T,Meng H,Yang T,Wang S,Wei T,Chen B,Ma Y,Wang Q,Wang H,Liu J,Wang L
Sat Mar 05 00:00:00 EST 2022
Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts.
Aging
Nojima I,Hosoda R,Toda Y,Saito Y,Ueda N,Horimoto K,Iwahara N,Horio Y,Kuno A
Mon Apr 04 00:00:00 EDT 2022
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging.
Theranostics
Lazzarini E,Lodrini AM,Arici M,Bolis S,Vagni S,Panella S,Rendon-Angel A,Saibene M,Metallo A,Torre T,Vassalli G,Ameri P,Altomare C,Rocchetti M,Barile L
Mon Jul 18 00:00:00 EDT 2022
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Cancer gene therapy
Wang F,Luo Y,Zhang L,Younis M,Yuan L
Tue Mar 01 00:00:00 EST 2022
HMGB1 induces radioresistance through PI3K/AKT/ATM pathway in esophageal squamous cell carcinoma.
Molecular biology reports
Zhang X,Zou N,Deng W,Song C,Yan K,Shen W,Zhu S
Thu Dec 01 00:00:00 EST 2022
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
Cells
Huang Z,Gan S,Zhuang X,Chen Y,Lu L,Wang Y,Qi X,Feng Q,Huang Q,Du B,Zhang R,Liu Z
Tue Aug 09 00:00:00 EDT 2022
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation.
Cell death and differentiation
Zhang P,Gao K,Zhang L,Sun H,Zhao X,Liu Y,Lv Z,Shi Q,Chen Y,Jiao D,Li Y,Gu W,Wang C
Fri Apr 01 00:00:00 EDT 2022
Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus.
Aging cell
Matias I,Diniz LP,Damico IV,Araujo APB,Neves LDS,Vargas G,Leite REP,Suemoto CK,Nitrini R,Jacob-Filho W,Grinberg LT,Hol EM,Middeldorp J,Gomes FCA
Sat Jan 01 00:00:00 EST 2022
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Frontiers in cardiovascular medicine
Wang S,Shi M,Zhou J,Wang W,Zhang Y,Li Y
Tue May 10 00:00:00 EDT 2022
Palmitic Acid, A Critical Metabolite, Aggravates Cellular Senescence Through Reactive Oxygen Species Generation in Kawasaki Disease.
Frontiers in pharmacology
Zhu Q,Dong Q,Wang X,Xia T,Fu Y,Wang Q,Wu R,Wu T
Wed Apr 13 00:00:00 EDT 2022
Effects of Low-Intensity Pulsed Ultrasound on the Migration and Homing of Human Amnion-Derived Mesenchymal Stem Cells to Ovaries in Rats With Premature Ovarian Insufficiency.
Cell transplantation
Ling L,Hou J,Wang Y,Shu H,Huang Y
Wed Oct 26 00:00:00 EDT 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer.
Cell reports
Gupta P,Strange K,Telange R,Guo A,Hatch H,Sobh A,Elie J,Carter AM,Totenhagen J,Tan C,Sonawane YA,Neuzil J,Natarajan A,Ovens AJ,Oakhill JS,Wiederhold T,Pacak K,Ghayee HK,Meijer L,Reddy S,Bibb JA
Tue Aug 16 00:00:00 EDT 2022
Ubiquitin-specific protease 3 attenuates interleukin-1β-mediated chondrocyte senescence by deacetylating forkhead box O-3 via sirtuin-3.
Bioengineered
Zhou Q,Wang W,Wu J,Qiu S,Yuan S,Fu PL,Qian QR,Xu YZ
Tue Feb 01 00:00:00 EST 2022
Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage.
Oxidative medicine and cellular longevity
Du D,Tang X,Li Y,Gao Y,Chen R,Chen Q,Wen J,Wu T,Zhang Y,Lu H,Zhang J,Wang S
Tue Jun 14 00:00:00 EDT 2022
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p.
Toxicology in vitro : an international journal published in association with BIBRA
Han W,Tao X,Weng T,Chen L
Tue Mar 01 00:00:00 EST 2022
Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling.
International journal of molecular sciences
Lee JJ,Ng SC,Hsu JY,Liu H,Chen CJ,Huang CY,Kuo WW
Wed Jan 26 00:00:00 EST 2022
Avenanthramide C induces cellular senescence in colorectal cancer cells via suppressing β-catenin-mediated the transcription of miR-183/96/182 cluster.
Biochemical pharmacology
Fu R,Dou Z,Li N,Zhang J,Li Z,Yang P
Sun May 01 00:00:00 EDT 2022
ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity.
Science advances
Xiao FH,Yu Q,Deng ZL,Yang K,Ye Y,Ge MX,Yan D,Wang HT,Chen XQ,Yang LQ,Yang BY,Lin R,Zhang W,Yang XL,Dong L,He Y,Zhou J,Cai WW,Li J,Kong QP
Fri Apr 29 00:00:00 EDT 2022
PGF2α-FP Receptor Ameliorates Senescence of VSMCs in Vascular Remodeling by Src/PAI-1 Signal Pathway.
Oxidative medicine and cellular longevity
Hu BA,Sai WW,Yuan J,Lan HT,Qi J,Wang D,Zhang W,Wang ZH,Zhong M,Shang YY
Wed Mar 09 00:00:00 EST 2022
Mechanism of Ba Zhen Tang Delaying Skin Photoaging Based on Network Pharmacology and Molecular Docking.
Clinical, cosmetic and investigational dermatology
Han M,Li H,Ke D,Tian LM,Hong Y,Zhang C,Tian DZ,Chen L,Zhan LR,Zong SQ
Sat Jul 16 00:00:00 EDT 2022
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Frontiers in immunology
Xiong G,Feng Y,Yi X,Zhang X,Li X,Yang L,Yi Z,Sai B,Yang Z,Zhang Q,Kuang Y,Zhu Y
Mon Oct 10 00:00:00 EDT 2022
Prognostic and immune correlation evaluation of a novel cuproptosis-related genes signature in hepatocellular carcinoma.
Frontiers in pharmacology
Zhou Z,Zhou Y,Liu D,Yang Q,Tang M,Liu W
Wed Jan 11 00:00:00 EST 2023
Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.
Nature structural & molecular biology
Barnes RP,de Rosa M,Thosar SA,Detwiler AC,Roginskaya V,Van Houten B,Bruchez MP,Stewart-Ornstein J,Opresko PL
Fri Jul 01 00:00:00 EDT 2022
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Bioactive materials
Luo L,Gong J,Wang Z,Liu Y,Cao J,Qin J,Zuo R,Zhang H,Wang S,Zhao P,Yang D,Zhang M,Wang Y,Zhang J,Zhou Y,Li C,Ni B,Tian Z,Liu M
Thu Sep 01 00:00:00 EDT 2022
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Bioactive materials
Luo L,Gong J,Wang Z,Liu Y,Cao J,Qin J,Zuo R,Zhang H,Wang S,Zhao P,Yang D,Zhang M,Wang Y,Zhang J,Zhou Y,Li C,Ni B,Tian Z,Liu M
Thu Sep 01 00:00:00 EDT 2022
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Bioactive materials
Luo L,Gong J,Wang Z,Liu Y,Cao J,Qin J,Zuo R,Zhang H,Wang S,Zhao P,Yang D,Zhang M,Wang Y,Zhang J,Zhou Y,Li C,Ni B,Tian Z,Liu M
Thu Sep 01 00:00:00 EDT 2022
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Oxidative medicine and cellular longevity
Ren C,Hu C,Wu Y,Li T,Zou A,Yu D,Shen T,Cai W,Yu J
Fri Jul 29 00:00:00 EDT 2022
FGFR2 accommodates osteogenic cell fate determination in human mesenchymal stem cells.
Gene
Zhang Y,Ling L,Ajay D/O Ajayakumar A,Eio YM,van Wijnen AJ,Nurcombe V,Cool SM
Fri Apr 15 00:00:00 EDT 2022
Lnc-IL7R alleviates PM2.5-mediated cellular senescence and apoptosis through EZH2 recruitment in chronic obstructive pulmonary disease.
Cell biology and toxicology
Lee KY,Ho SC,Sun WL,Feng PH,Lin CW,Chen KY,Chuang HC,Tseng CH,Chen TT,Wu SM
Thu Dec 01 00:00:00 EST 2022
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
Experimental eye research
Gao F,Wang L,Wu B,Ou Q,Tian H,Xu J,Jin C,Zhang J,Wang J,Lu L,Xu GT
Sat Oct 01 00:00:00 EDT 2022
Long-Term Social Isolation-Induced Autophagy Inhibition and Cell Senescence Aggravate Cognitive Impairment in D(+)Galactose-Treated Male Mice.
Frontiers in aging neuroscience
Wang B,Ntim M,Xia M,Wang Y,Lu JC,Yang JY,Li S
Wed Apr 13 00:00:00 EDT 2022
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer.
Nature communications
Palafox M,Monserrat L,Bellet M,Villacampa G,Gonzalez-Perez A,Oliveira M,Brasó-Maristany F,Ibrahimi N,Kannan S,Mina L,Herrera-Abreu MT,Òdena A,Sánchez-Guixé M,Capelán M,Azaro A,Bruna A,Rodríguez O,Guzmán M,Grueso J,Viaplana C,Hernández J,Su F,Lin K,Clarke RB,Caldas C,Arribas J,Michiels S,García-Sanz A,Turner NC,Prat A,Nuciforo P,Dienstmann R,Verma CS,Lopez-Bigas N,Scaltriti M,Arnedos M,Saura C,Serra V
Wed Sep 07 00:00:00 EDT 2022
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Science (New York, N.Y.)
Gulluni F,Prever L,Li H,Krafcikova P,Corrado I,Lo WT,Margaria JP,Chen A,De Santis MC,Cnudde SJ,Fogerty J,Yuan A,Massarotti A,Sarijalo NT,Vadas O,Williams RL,Thelen M,Powell DR,Schueler M,Wiesener MS,Balla T,Baris HN,Tiosano D,McDermott BM,Perkins BD,Ghigo A,Martini M,Haucke V,Boura E,Merlo GR,Buchner DA,Hirsch E
Fri Dec 10 00:00:00 EST 2021
IL-21 Is an Accomplice of PD-L1 in the Induction of PD-1-Dependent Treg Generation in Head and Neck Cancer.
Frontiers in oncology
Zhao Y,Zhang Z,Lei W,Wei Y,Ma R,Wen Y,Wei F,Fan J,Xu Y,Chen L,Lyu K,Lin H,Wen W,Sun W
Wed May 26 00:00:00 EDT 2021
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Oxidative medicine and cellular longevity
Luo R,Li S,Li G,Lu S,Zhang W,Liu H,Lei J,Ma L,Ke W,Liao Z,Wang B,Song Y,Wang K,Zhang Y,Yang C
Wed Jan 05 00:00:00 EST 2022
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Cell death discovery
Li P,Liu X,Zhao T,Li F,Wang Q,Zhang P,Hirayama R,Chen W,Jin X,Zheng X,Wang Z,Li Q
Tue Jul 20 00:00:00 EDT 2021
Extracts of Jasminum sambac flowers fermented by Lactobacillus rhamnosus inhibit H2 O2 - and UVB-induced aging in human dermal fibroblasts.
Environmental toxicology
Ho CC,Ng SC,Chuang HL,Wen SY,Kuo CH,Mahalakshmi B,Huang CY,Kuo WW
Thu Apr 01 00:00:00 EDT 2021
Design and synthesis of water-soluble grifolin prodrugs for DNA methyltransferase 1 (DNMT1) down-regulation.
RSC advances
Wang L,Wu Y,Li Z,Lan T,Zhao X,Lv W,Shi F,Luo X,Rao Y,Cao Y
Mon Nov 29 00:00:00 EST 2021
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury.
Communications biology
Uryga AK,Grootaert MOJ,Garrido AM,Oc S,Foote K,Chappell J,Finigan A,Rossiello F,d'Adda di Fagagna F,Aravani D,Jorgensen HF,Bennett MR
Fri May 21 00:00:00 EDT 2021
eIF3a R803K mutation mediates chemotherapy resistance by inducing cellular senescence in small cell lung cancer.
Pharmacological research
Chen YX,Wang CJ,Xiao DS,He BM,Li M,Yi XP,Zhang W,Yin JY,Liu ZQ
Wed Dec 01 00:00:00 EST 2021
Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence-associated secretory phenotype.
Journal of extracellular vesicles
Wallis R,Josipovic N,Mizen H,Robles-Tenorio A,Tyler EJ,Papantonis A,Bishop CL
Mon Feb 01 00:00:00 EST 2021
Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence-associated secretory phenotype.
Journal of extracellular vesicles
Wallis R,Josipovic N,Mizen H,Robles-Tenorio A,Tyler EJ,Papantonis A,Bishop CL
Mon Feb 01 00:00:00 EST 2021
Protective effects of galangin against H2O2/UVB-induced dermal fibroblast collagen degradation via hsa-microRNA-4535-mediated TGFβ/Smad signaling.
Aging
Lee JJ,Ng SC,Ni YT,Liu JS,Chen CJ,Padma VV,Huang CY,Kuo WW
Fri Dec 10 00:00:00 EST 2021
Statins Mitigate Stress-Related Vascular Aging and Atherosclerosis in apoE-Deficient Mice Fed High Fat-Diet: The Role of Glucagon-Like Peptide-1/Adiponectin Axis.
Frontiers in cell and developmental biology
Lei Y,Cui Q,Yang G,Piao L,Inoue A,Wu H,Li X,Kuzuya M,Cheng XW
Mon Apr 25 00:00:00 EDT 2022
Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression.
Aging
Tian L,Ke D,Hong Y,Zhang C,Tian D,Chen L,Zhan L,Zong S
Thu Dec 09 00:00:00 EST 2021
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53.
Integrative cancer therapies
Wang L,Xu L,Wang Y
Mon Oct 11 00:00:00 EDT 2021
Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A.
Scientific reports
Kang SM,Yoon MH,Lee SJ,Ahn J,Yi SA,Nam KH,Park S,Woo TG,Cho JH,Lee J,Ha NC,Park BJ
Tue Apr 27 00:00:00 EDT 2021
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
ACS chemical neuroscience
Gao L,Zheng WG,Wu XK,Du GH,Qin XM
Wed Jul 07 00:00:00 EDT 2021
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Stem cell reviews and reports
Liao X,Wu C,Shao Z,Zhang S,Zou Y,Wang K,Ha Y,Xing J,Zheng A,Shen Z,Zheng S,Guo J,Jie W
Sun Aug 01 00:00:00 EDT 2021
Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell-Derived Exosomes on the Senescence of Nucleus Pulposus Cells.
Orthopaedic surgery
Chen CC,Chen J,Wang WL,Xie L,Shao CQ,Zhang YX
Thu Apr 01 00:00:00 EDT 2021
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Free radical biology & medicine
Jia R,Yang F,Yan P,Ma L,Yang L,Li L
Tue Jun 01 00:00:00 EDT 2021
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Oxidative medicine and cellular longevity
Zhang Y,Lv Z,Liu Y,Cao H,Yang J,Wang B
Thu Dec 30 00:00:00 EST 2021
Targeting senescent cells improves functional recovery after spinal cord injury.
Cell reports
Paramos-de-Carvalho D,Martins I,Cristóvão AM,Dias AF,Neves-Silva D,Pereira T,Chapela D,Farinho A,Jacinto A,Saúde L
Tue Jul 06 00:00:00 EDT 2021
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
eLife
Gautheron J,Morisseau C,Chung WK,Zammouri J,Auclair M,Baujat G,Capel E,Moulin C,Wang Y,Yang J,Hammock BD,Cerame B,Phan F,Fève B,Vigouroux C,Andreelli F,Jeru I
Tue Aug 03 00:00:00 EDT 2021
Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling.
Nature aging
Cai D,Han JJ
Sat May 01 00:00:00 EDT 2021
NFATc4 mediates ethanol-triggered hepatocyte senescence.
Toxicology letters
Wu R,Wang X,Shao Y,Jiang Y,Zhou Y,Lu C
Sun Oct 10 00:00:00 EDT 2021
NFATc4 mediates ethanol-triggered hepatocyte senescence.
Toxicology letters
Wu R,Wang X,Shao Y,Jiang Y,Zhou Y,Lu C
Sun Oct 10 00:00:00 EDT 2021
One-Two Punch Therapy for the Treatment of T-Cell Malignancies Involving p53-Dependent Cellular Senescence.
Oxidative medicine and cellular longevity
Qing Y,Li H,Zhao Y,Hu P,Wang X,Yu X,Zhu M,Wang H,Wang Z,Guo Q,Hui H
Mon Jan 31 00:00:00 EST 2022
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
Frontiers in oncology
Zhang D,Lu P,Zhu K,Wu H,Dai Y
Tue Nov 23 00:00:00 EST 2021
Dipeptidyl peptidase-4 inhibition prevents lung injury in mice under chronic stress via the modulation of oxidative stress and inflammation.
Experimental animals
Zhang S,Li P,Xin M,Jin X,Zhao L,Nan Y,Cheng XW
Wed Nov 10 00:00:00 EST 2021
Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome.
Communications biology
Kang SM,Yoon MH,Ahn J,Kim JE,Kim SY,Kang SY,Joo J,Park S,Cho JH,Woo TG,Oh AY,Chung KJ,An SY,Hwang TS,Lee SY,Kim JS,Ha NC,Song GY,Park BJ
Mon Jan 04 00:00:00 EST 2021
TFEB protein expression is reduced in aged brains and its overexpression mitigates senescence-associated biomarkers and memory deficits in mice.
Neurobiology of aging
Wang H,Muthu Karuppan MK,Devadoss D,Nair M,Chand HS,Lakshmana MK
Fri Oct 01 00:00:00 EDT 2021
miR-127-3p Is an Epigenetic Activator of Myofibroblast Senescence Situated within the MicroRNA-Enriched Dlk1-Dio3‒Imprinted Domain on Mouse Chromosome 12.
The Journal of investigative dermatology
Auler M,Bergmeier V,Georgieva VS,Pitzler L,Frie C,Nüchel J,Eckes B,Hinz B,Brachvogel B
Thu Apr 01 00:00:00 EDT 2021
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
Frontiers in medicine
Song H,Zhuang L,Xu X,Shi J,Hu W,Liu Z,Shi S
Tue Dec 21 00:00:00 EST 2021
Irradiation Accelerates Plaque Formation and Cellular Senescence in Flow-Altered Carotid Arteries of Apolipoprotein E Knock-Out Mice.
Journal of the American Heart Association
Yamamoto Y,Minami M,Yoshida K,Nagata M,Miyata T,Yang T,Takayama N,Suzuki K,Okawa M,Yamada K,Miyamoto S
Tue Jul 20 00:00:00 EDT 2021
Expression of p16 Within Myenteric Neurons of the Aged Colon: A Potential Marker of Declining Function.
Frontiers in neuroscience
Palmer A,Epton S,Crawley E,Straface M,Gammon L,Edgar MM,Xu Y,Elahi S,Chin-Aleong J,Martin JE,Bishop CL,Knowles CH,Sanger GJ
Tue Oct 26 00:00:00 EDT 2021
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Mechanisms of ageing and development
Zhong H,Zhou Z,Guo L,Liu F,Zheng B,Bi S,Tian C
Mon Mar 01 00:00:00 EST 2021
Muse Cells Have Higher Stress Tolerance than Adipose Stem Cells due to the Overexpression of the CCNA2 Gene.
Stem cells and development
Wang P,Wang S,Ji F,Zhang R
Mon Nov 01 00:00:00 EDT 2021
BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
Aging
Shao Y,Zhao C,Pan J,Zeng C,Zhang H,Liu L,Fan K,Liu X,Luo B,Fang H,Bai X,Zhang H,Cai D
Fri Mar 19 00:00:00 EDT 2021
BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
Aging
Shao Y,Zhao C,Pan J,Zeng C,Zhang H,Liu L,Fan K,Liu X,Luo B,Fang H,Bai X,Zhang H,Cai D
Fri Mar 19 00:00:00 EDT 2021
CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent manner.
The Journal of biological chemistry
Chen YC,Hsieh HH,Chang HC,Wang HC,Lin WJ,Lin JJ
Wed Aug 18 00:00:00 EDT 2021
Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension.
BMC pulmonary medicine
Li K,Li Y,Yu Y,Ding J,Huang H,Chu C,Hu L,Yu Y,Cao Y,Xu P,Fulton D,Chen F
Fri Mar 05 00:00:00 EST 2021
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Stem cells international
Zhang S,Zhang R,Qiao P,Ma X,Lu R,Wang F,Li C,E L,Liu H
Sat Jan 30 00:00:00 EST 2021
HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress.
Redox biology
Thangaraj A,Chivero ET,Tripathi A,Singh S,Niu F,Guo ML,Pillai P,Periyasamy P,Buch S
Thu Apr 01 00:00:00 EDT 2021
HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress.
Redox biology
Thangaraj A,Chivero ET,Tripathi A,Singh S,Niu F,Guo ML,Pillai P,Periyasamy P,Buch S
Thu Apr 01 00:00:00 EDT 2021
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma.
Cancer biology & medicine
Chen T,Liu L,Zou Y,Hu X,Zhang W,Zhou T,Luo X,Fu W,Xu J
Mon Feb 15 00:00:00 EST 2021
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Stem cell research & therapy
Tan YZ,Xu XY,Dai JM,Yin Y,He XT,Zhang YL,Zhu TX,An Y,Tian BM,Chen FM
Thu Apr 29 00:00:00 EDT 2021
PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair.
Frontiers in cell and developmental biology
Wang Y,Sui Y,Lian A,Han X,Liu F,Zuo K,Liu M,Sun W,Wang Z,Liu Z,Zou F,Lu R,Jin M,Du H,Xu K,Liu X,Liu J
Tue Dec 07 00:00:00 EST 2021
Pim1 knockout alleviates sarcopenia in aging mice via reducing adipogenic differentiation of PDGFRα+ mesenchymal progenitors.
Journal of cachexia, sarcopenia and muscle
Shang GK,Han L,Wang ZH,Song M,Wang D,Tan YM,Li YH,Li YL,Zhang W,Zhong M
Wed Dec 01 00:00:00 EST 2021
Smad4 deficiency substitutes Cdkn2b but not Cdkn2a downregulation in pancreatic cancer following induction of genetic events in adult mice.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Jia X,Sun B,Tu Q,Qi H,Li L,Liu X,Yan L,Dai H,Kong Q,Tang C,Zhao X
Mon Mar 01 00:00:00 EST 2021
Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.
iScience
Zhang J,Gao F,Ma Y,Xue T,Shen Y
Fri Nov 19 00:00:00 EST 2021
Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.
iScience
Zhang J,Gao F,Ma Y,Xue T,Shen Y
Fri Nov 19 00:00:00 EST 2021
P16 a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.
Frontiers in cell and developmental biology
Zhou J,Hou C,Chen H,Qin Z,Miao Z,Zhao J,Wang Q,Cui M,Xie C,Wang R,Li Q,Zuo G,Miao D,Jin J
Sat Oct 30 00:00:00 EDT 2021
Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer.
Cell cycle (Georgetown, Tex.)
Gao Q,Wu Y,Lu C,Kai W,Xie W,Wang Q,Wang L,Liu S,Pan Y
Wed Dec 01 00:00:00 EST 2021
Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer.
Cell cycle (Georgetown, Tex.)
Gao Q,Wu Y,Lu C,Kai W,Xie W,Wang Q,Wang L,Liu S,Pan Y
Wed Dec 01 00:00:00 EST 2021
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Stem cell research & therapy
Liu J,He J,Ge L,Xiao H,Huang Y,Zeng L,Jiang Z,Lu M,Hu Z
Thu Jul 22 00:00:00 EDT 2021
The Extracellular Metabolome Stratifies Low and High Risk Potentially Premalignant Oral Keratinocytes and Identifies Citrate as a Potential Non-Invasive Marker of Tumour Progression.
Cancers
Karen-Ng LP,James EL,Stephen A,Bennett MH,Mycielska ME,Parkinson EK
Sat Aug 21 00:00:00 EDT 2021
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Laboratory investigation; a journal of technical methods and pathology
Zhang L,Liu M,Liu W,Hu C,Li H,Deng J,Cao Q,Wang Y,Hu W,Li Q
Mon Nov 01 00:00:00 EDT 2021
Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes.
International journal of molecular medicine
Sun X,Fu P,Xie L,Chai S,Xu Q,Zeng L,Wang X,Jiang N,Sang M
Fri Jan 01 00:00:00 EST 2021
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Aging
Pei Z,Yang C,Guo Y,Dong M,Wang F
Tue Sep 14 00:00:00 EDT 2021
Senolytic CAR T cells reverse senescence-associated pathologies.
Nature
Amor C,Feucht J,Leibold J,Ho YJ,Zhu C,Alonso-Curbelo D,Mansilla-Soto J,Boyer JA,Li X,Giavridis T,Kulick A,Houlihan S,Peerschke E,Friedman SL,Ponomarev V,Piersigilli A,Sadelain M,Lowe SW
Wed Jul 01 00:00:00 EDT 2020
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis.
Haematologica
Godavarthy PS,Kumar R,Herkt SC,Pereira RS,Hayduk N,Weissenberger ES,Aggoune D,Manavski Y,Lucas T,Pan KT,Voutsinas JM,Wu Q,Müller MC,Saussele S,Oellerich T,Oehler VG,Lausen J,Krause DS
Wed Jan 01 00:00:00 EST 2020
HO-1 overexpression alleviates senescence by inducing autophagy via the mitochondrial route in human nucleus pulposus cells.
Journal of cellular physiology
Yi W,Lan H,Wen Y,Wang Y,He D,Bai Z,Zhang Y,Jiang W,Liu B,Shen J,Hu Z
Sun Nov 01 00:00:00 EDT 2020
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Frontiers in cell and developmental biology
Lv F,Li N,Kong M,Wu J,Fan Z,Miao D,Xu Y,Ye Q,Wang Y
Mon Sep 28 00:00:00 EDT 2020
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Frontiers in cell and developmental biology
Lv F,Li N,Kong M,Wu J,Fan Z,Miao D,Xu Y,Ye Q,Wang Y
Mon Sep 28 00:00:00 EDT 2020
Increased production of functional small extracellular vesicles in senescent endothelial cells.
Journal of cellular and molecular medicine
Riquelme JA,Takov K,Santiago-Fernández C,Rossello X,Lavandero S,Yellon DM,Davidson SM
Wed Apr 01 00:00:00 EDT 2020
Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A.
Redox biology
Göbl C,Morris VK,van Dam L,Visscher M,Polderman PE,Hartlmüller C,de Ruiter H,Hora M,Liesinger L,Birner-Gruenberger R,Vos HR,Reif B,Madl T,Dansen TB
Wed Jan 01 00:00:00 EST 2020
Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics.
International journal of molecular sciences
Honda Y,Huang A,Tanaka T,Han X,Gao B,Liu H,Wang X,Zhao J,Hashimoto Y,Yamamoto K,Matsumoto N,Baba S,Umeda M
Sat Jun 13 00:00:00 EDT 2020
Piwi-interacting RNAs play a role in vitamin C-mediated effects on endothelial aging.
International journal of medical sciences
Zheng S,Zheng H,Huang A,Mai L,Huang X,Hu Y,Huang Y
Wed Feb 24 00:00:00 EST 2021
Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.
Aging cell
Dang Y,An Y,He J,Huang B,Zhu J,Gao M,Zhang S,Wang X,Yang B,Xie Z
Wed Jan 01 00:00:00 EST 2020
Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation.
Oxidative medicine and cellular longevity
Feng H,Mou SQ,Li WJ,Zhang N,Zhou ZY,Ding W,Bian ZY,Liao HH
Wed May 12 00:00:00 EDT 2021
Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation.
Oxidative medicine and cellular longevity
Feng H,Mou SQ,Li WJ,Zhang N,Zhou ZY,Ding W,Bian ZY,Liao HH
Wed May 12 00:00:00 EDT 2021
Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells.
Frontiers in physiology
Stojanović SD,Fuchs M,Kunz M,Xiao K,Just A,Pich A,Bauersachs J,Fiedler J,Sedding D,Thum T
Mon Sep 28 00:00:00 EDT 2020
TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs.
Cell cycle (Georgetown, Tex.)
Foster DJ,Chang HM,Haswell JR,Gregory RI,Slack FJ
Tue Sep 01 00:00:00 EDT 2020
Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model.
Nature genetics
Sethi NS,Kikuchi O,Duronio GN,Stachler MD,McFarland JM,Ferrer-Luna R,Zhang Y,Bao C,Bronson R,Patil D,Sanchez-Vega F,Liu JB,Sicinska E,Lazaro JB,Ligon KL,Beroukhim R,Bass AJ
Sat Feb 01 00:00:00 EST 2020
PAI-1 Regulation of TGF-β1-induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages.
American journal of respiratory cell and molecular biology
Rana T,Jiang C,Liu G,Miyata T,Antony V,Thannickal VJ,Liu RM
Sun Mar 01 00:00:00 EST 2020
FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
Cell metabolism
Wang L,Chen R,Li G,Wang Z,Liu J,Liang Y,Liu JP
Tue Nov 03 00:00:00 EST 2020
Paclitaxel exposure downregulates miR-522 expression and its downregulation induces paclitaxel resistance in ovarian cancer cells.
Scientific reports
Miyamoto M,Sawada K,Nakamura K,Yoshimura A,Ishida K,Kobayashi M,Shimizu A,Yamamoto M,Kodama M,Hashimoto K,Kimura T
Wed Oct 07 00:00:00 EDT 2020
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Aging
Wang J,Li S,Wang J,Wu F,Chen Y,Zhang H,Guo Y,Lin Y,Li L,Yu X,Liu T,Zhao Y
Mon Jan 06 00:00:00 EST 2020
Role and mechanism of FLNa and UCP2 in the development of cervical cancer.
Oncology reports
Wang A,Liu L,Yuan M,Han S,You X,Zhang H,Lei F,Zhang Y
Tue Dec 01 00:00:00 EST 2020
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
Mechanisms of ageing and development
Wang X,Li D,Wu H,Liu F,Liu F,Zhang Q,Li J
Tue Sep 01 00:00:00 EDT 2020
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Fundamental & clinical pharmacology
Wang S,Wang H,Sun B,Li D,Wu J,Li J,Tian X,Qin C,Chang H,Liu Y
Sat Feb 01 00:00:00 EST 2020
A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
Journal of cellular and molecular medicine
Jia Y,Jin H,Gao L,Yang X,Wang F,Ding H,Chen A,Tan S,Zhang F,Shao J,Wang S,Zheng S
Fri May 01 00:00:00 EDT 2020
A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
Journal of cellular and molecular medicine
Jia Y,Jin H,Gao L,Yang X,Wang F,Ding H,Chen A,Tan S,Zhang F,Shao J,Wang S,Zheng S
Fri May 01 00:00:00 EDT 2020
Nrf2 modulates immunosuppressive ability and cellular senescence of human umbilical cord mesenchymal stem cells.
Biochemical and biophysical research communications
Jie Z,Huan Y,Mengyun W,Yasha L,Huafeng P,Ke Y
Thu Jun 11 00:00:00 EDT 2020
Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation.
Biochemical and biophysical research communications
Lin J,Xu R,Shen X,Jiang H,Du S
Thu Oct 15 00:00:00 EDT 2020
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Theranostics
Zou G,Zhang X,Wang L,Li X,Xie T,Zhao J,Yan J,Wang L,Ye H,Jiao S,Xiang R,Shi Y
Tue May 18 00:00:00 EDT 2021
Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p.
Pathology, research and practice
Dao R,Wudu M,Hui L,Jiang J,Xu Y,Ren H,Qiu X
Sun Mar 01 00:00:00 EST 2020
High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis.
Frontiers in pharmacology
Maique J,Flores B,Shi M,Shepard S,Zhou Z,Yan S,Moe OW,Hu MC
Fri Apr 09 00:00:00 EDT 2021
Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
Biotechnology letters
Wang B,Liu F,Liu Z,Han X,Lian A,Zhang Y,Zuo K,Wang Y,Liu M,Zou F,Jiang Y,Jin M,Liu X,Liu J
Thu Oct 01 00:00:00 EDT 2020
Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR.
Aging
Feng X,Pan J,Li J,Zeng C,Qi W,Shao Y,Liu X,Liu L,Xiao G,Zhang H,Bai X,Cai D
Thu Jan 16 00:00:00 EST 2020
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Molecular neurobiology
Guo Y,Li H,Ke X,Deng M,Wu Z,Cai Y,Afewerky HK,Zhang X,Pei L,Lu Y
Wed May 01 00:00:00 EDT 2019
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Molecular neurobiology
Guo Y,Li H,Ke X,Deng M,Wu Z,Cai Y,Afewerky HK,Zhang X,Pei L,Lu Y
Wed May 01 00:00:00 EDT 2019
A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model.
Molecular carcinogenesis
Fan X,Bjerke GA,Riemondy K,Wang L,Yi R
Sun Dec 01 00:00:00 EST 2019
Phenotypic and functional differences between senescent and aged murine microglia.
Neurobiology of aging
Stojiljkovic MR,Ain Q,Bondeva T,Heller R,Schmeer C,Witte OW
Fri Feb 01 00:00:00 EST 2019
Phenotypic and functional differences between senescent and aged murine microglia.
Neurobiology of aging
Stojiljkovic MR,Ain Q,Bondeva T,Heller R,Schmeer C,Witte OW
Fri Feb 01 00:00:00 EST 2019
Aberrant methylation-induced dysfunction of p16 is associated with osteoblast activation caused by fluoride.
Environmental toxicology
Wu S,Yan W,Qiu B,Liao Y,Gu J,Wei S,Zhang A,Pan X
Tue Jan 01 00:00:00 EST 2019
Aberrant methylation-induced dysfunction of p16 is associated with osteoblast activation caused by fluoride.
Environmental toxicology
Wu S,Yan W,Qiu B,Liao Y,Gu J,Wei S,Zhang A,Pan X
Tue Jan 01 00:00:00 EST 2019
Histone Deacetylation in the Promoter of p16 Is Involved in Fluoride-Induced Human Osteoblast Activation via the Inhibition of Sp1 Binding.
Biological trace element research
Ming J,Wu S,You T,Wang X,Yu C,Luo P,Zhang A,Pan X
Mon Apr 01 00:00:00 EDT 2019
Histone Deacetylation in the Promoter of p16 Is Involved in Fluoride-Induced Human Osteoblast Activation via the Inhibition of Sp1 Binding.
Biological trace element research
Ming J,Wu S,You T,Wang X,Yu C,Luo P,Zhang A,Pan X
Mon Apr 01 00:00:00 EDT 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
Dipeptidyl peptidase-4 inhibition prevents vascular aging in mice under chronic stress: Modulation of oxidative stress and inflammation.
Chemico-biological interactions
Xin M,Jin X,Cui X,Jin C,Piao L,Wan Y,Xu S,Zhang S,Yue X,Wang H,Nan Y,Cheng X
Sun Dec 01 00:00:00 EST 2019
p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation.
Cell death & disease
Yoon MH,Kang SM,Lee SJ,Woo TG,Oh AY,Park S,Ha NC,Park BJ
Wed Feb 06 00:00:00 EST 2019
Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis.
Journal of immunology (Baltimore, Md. : 1950)
Saito N,Araya J,Ito S,Tsubouchi K,Minagawa S,Hara H,Ito A,Nakano T,Hosaka Y,Ichikawa A,Kadota T,Yoshida M,Fujita Y,Utsumi H,Kurita Y,Kobayashi K,Hashimoto M,Wakui H,Numata T,Kaneko Y,Asano H,Odaka M,Ohtsuka T,Morikawa T,Nakayama K,Kuwano K
Fri Mar 01 00:00:00 EST 2019
Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer.
Frontiers in oncology
Guo S,Jian L,Tao K,Chen C,Yu H,Liu S
Thu Oct 01 00:00:00 EDT 2020
Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells.
International journal of molecular medicine
Wen SY,Cheng SY,Ng SC,Aneja R,Chen CJ,Huang CY,Kuo WW
Sun Dec 01 00:00:00 EST 2019
Overexpression of P16 reversed the MDR1-mediated DDP resistance in the cervical adenocarcinoma by activating the ERK1/2 signaling pathway.
Cell division
Xiao Y,Liang MR,Liu CC,Wang YN,Zeng Y,Zhou J,Zhu HT,Wang Q,Zou Y,Zeng SY
Sat Apr 09 00:00:00 EDT 2022
Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma.
Oncology letters
Jia J,Yin P,Zhang X,Yang F,Song G,Bi W,Han G,Xu M,Wang W,Zheng X
Sat Jun 01 00:00:00 EDT 2019
Tumor necrosis factor-inducible gene 6 reprograms hepatic stellate cells into stem-like cells, which ameliorates liver damage in mouse.
Biomaterials
Wang S,Kim J,Lee C,Oh D,Han J,Kim TJ,Kim SW,Seo YS,Oh SH,Jung Y
Tue Oct 01 00:00:00 EDT 2019
A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma.
American journal of cancer research
Li Z,Zhu T,Xu Y,Wu C,Chen J,Ren Y,Kong L,Sun S,Guo W,Wang Y,Jing C,Dong J,Zhou J,Zhang L,Shen Q,Zhou X
Thu Oct 01 00:00:00 EDT 2020
S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
Aging
Su Y,Xu C,Sun Z,Liang Y,Li G,Tong T,Chen J
Wed Jan 23 00:00:00 EST 2019
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
Free radical biology & medicine
Li R,Liu Y,Xie J,Huang X,Zhang L,Liu H,Li L
Wed May 01 00:00:00 EDT 2019
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Signal transduction and targeted therapy
Li Y,Li X,Cao M,Jiang Y,Yan J,Liu Z,Yang R,Chen X,Sun P,Xiang R,Wang L,Shi Y
Fri Jan 29 00:00:00 EST 2021
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 EDT 2019
Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence.
Nature communications
Saxena S,Vekaria H,Sullivan PG,Seifert AW
Fri Sep 27 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Fra-1 plays a critical role in angiotensin II-induced vascular senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang D,Xiao C,Long F,Wu W,Huang M,Qu L,Liu X,Zhu Y
Sat Jun 01 00:00:00 EDT 2019
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Molecular cancer research : MCR
Yang J,Zeng Z,Qiao L,Jiang X,Ma J,Wang J,Ye S,Ma Q,Wei J,Wu M,Huang X,Ma D,Gao Q
Tue Oct 01 00:00:00 EDT 2019
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
Artificial cells, nanomedicine, and biotechnology
Li T,Xiong Y,Wang Q,Chen F,Zeng Y,Yu X,Wang Y,Zhou F,Zhou Y
Sun Dec 01 00:00:00 EST 2019
Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma.
EBioMedicine
Yun D,Wang H,Wang Y,Chen Y,Zhao Z,Ma J,Ji Y,Huang Q,Chen J,Chen H,Lu D
Fri Feb 01 00:00:00 EST 2019
Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression.
Oncology reports
Zhang X,Yang X,Zhu S,Li Q,Zou N
Fri Mar 01 00:00:00 EST 2019
PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis.
Stem cell research & therapy
Jiang Y,Liu F,Zou F,Zhang Y,Wang B,Zhang Y,Lian A,Han X,Liu Z,Liu X,Jin M,Wang D,Li G,Liu J
Fri Aug 23 00:00:00 EDT 2019
P16 Methylation Leads to Paclitaxel Resistance of Advanced Non-Small Cell Lung Cancer.
Journal of Cancer
Liu Z,Lin H,Gan Y,Cui C,Zhang B,Gu L,Zhou J,Zhu G,Deng D
Tue Sep 29 00:00:00 EDT 2020
MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages.
Journal of molecular and cellular cardiology
An J,Naruse TK,Hinohara K,Soejima Y,Sawabe M,Nakagawa Y,Kuwahara K,Kimura A
Thu Aug 01 00:00:00 EDT 2019
lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
Aging
Lin X,Zhan JK,Zhong JY,Wang YJ,Wang Y,Li S,He JY,Tan P,Chen YY,Liu XB,Cui XJ,Liu YS
Thu Jan 17 00:00:00 EST 2019
NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.
Oxidative medicine and cellular longevity
Liu F,Shi J,Zhang Y,Lian A,Han X,Zuo K,Liu M,Zheng T,Zou F,Liu X,Jin M,Mu Y,Li G,Su G,Liu J
Thu Jun 11 00:00:00 EDT 2020
Stem cell competition orchestrates skin homeostasis and ageing.
Nature
Liu N,Matsumura H,Kato T,Ichinose S,Takada A,Namiki T,Asakawa K,Morinaga H,Mohri Y,De Arcangelis A,Geroges-Labouesse E,Nanba D,Nishimura EK
Mon Apr 01 00:00:00 EDT 2019
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xiong Y,Li T,Assani G,Ling H,Zhou Q,Zeng Y,Zhou F,Zhou Y
Mon Apr 01 00:00:00 EDT 2019
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway.
Aging cell
Xu S,Wu W,Huang H,Huang R,Xie L,Su A,Liu S,Zheng R,Yuan Y,Zheng HL,Sun X,Xiong XD,Liu X
Sat Jun 01 00:00:00 EDT 2019
A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal.
Disease models & mechanisms
Tu Q,Yang D,Zhang X,Jia X,An S,Yan L,Dai H,Ma Y,Tang C,Tong W,Hou Z,Lv L,Tan J,Zhao X
Mon Apr 15 00:00:00 EDT 2019
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
Aging
Li Y,Kong R,Chen H,Zhao Z,Li L,Li J,Hu J,Zhang G,Pan S,Wang Y,Wang G,Chen H,Sun B
Sun Jul 21 00:00:00 EDT 2019
New Insights into Chronological Mobility of Retrotransposons In Vivo.
Oxidative medicine and cellular longevity
Ghanam AR,Cao J,Ouyang X,Song X
Fri Feb 21 00:00:00 EST 2020
Interferon Regulatory Factor 3 Deficiency Induces Age-Related Alterations of the Retina in Young and Old Mice.
Frontiers in cellular neuroscience
Zhang X,Zhu J,Chen X,Jie-Qiong Z,Li X,Luo L,Huang H,Liu W,Zhou X,Yan J,Lin S,Ye J
Wed Sep 30 00:00:00 EDT 2020
MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1.
Oncogene
Cao Z,Xue J,Cheng Y,Wang J,Liu Y,Li H,Jiang W,Li G,Gui Y,Zhang X
Sat Jun 01 00:00:00 EDT 2019
Senescence caused by inactivation of the homeodomain transcription factor Pdx1 in adult pancreatic acinar cells in mice.
FEBS letters
Horiguchi M,Yoshida M,Hirata K,Furuyama K,Masui T,Uemoto S,Kawaguchi Y
Thu Aug 01 00:00:00 EDT 2019
The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways.
Molecular and cellular biology
Cho W,Jin X,Pang J,Wang Y,Mivechi NF,Moskophidis D
Wed May 01 00:00:00 EDT 2019
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Life science alliance
Tian S,Feng J,Cao Y,Shen S,Cai Y,Yang D,Yan R,Wang L,Zhang H,Zhong X,Gao P
Tue Oct 01 00:00:00 EDT 2019
Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria.
Materials (Basel, Switzerland)
Zhao J,Honda Y,Tanaka T,Hashimoto Y,Matsumoto N
Mon Dec 23 00:00:00 EST 2019
Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development.
Aging
Malaise O,Tachikart Y,Constantinides M,Mumme M,Ferreira-Lopez R,Noack S,Krettek C,Noël D,Wang J,Jorgensen C,Brondello JM
Tue Oct 22 00:00:00 EDT 2019
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
The Journal of biological chemistry
Delfarah A,Parrish S,Junge JA,Yang J,Seo F,Li S,Mac J,Wang P,Fraser SE,Graham NA
Fri Jul 05 00:00:00 EDT 2019
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
BMC cancer
Shen Z,Liao X,Shao Z,Feng M,Yuan J,Wang S,Gan S,Ha Y,He Z,Jie W
Fri Mar 22 00:00:00 EDT 2019
Cathepsin S Deficiency Mitigated Chronic Stress-Related Neointimal Hyperplasia in Mice.
Journal of the American Heart Association
Wang H,Meng X,Piao L,Inoue A,Xu W,Yu C,Nakamura K,Hu L,Sasaki T,Wu H,Unno K,Umegaki H,Murohara T,Shi GP,Kuzuya M,Cheng XW
Tue Jul 16 00:00:00 EDT 2019
Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells.
British journal of pharmacology
Liang J,Li Q,Cai W,Zhang X,Yang B,Li X,Jiang S,Tian S,Zhang K,Song H,Ai D,Zhang X,Wang C,Zhu Y
Sun Sep 01 00:00:00 EDT 2019
Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
Journal of cellular physiology
Sui A,Xu Y,Pan B,Guo T,Wu J,Shen Y,Yang J,Guo X
Thu Aug 01 00:00:00 EDT 2019
Lack of Cardiac Improvement After Cardiosphere-Derived Cell Transplantation in Aging Mouse Hearts.
Circulation research
Zhao ZA,Han X,Lei W,Li J,Yang Z,Wu J,Yao M,Lu XA,He L,Chen Y,Zhou B,Hu S
Fri Oct 26 00:00:00 EDT 2018
Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Thangavel C,Boopathi E,Liu Y,McNair C,Haber A,Perepelyuk M,Bhardwaj A,Addya S,Ertel A,Shoyele S,Birbe R,Salvino JM,Dicker AP,Knudsen KE,Den RB
Thu Mar 15 00:00:00 EDT 2018
Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Thangavel C,Boopathi E,Liu Y,McNair C,Haber A,Perepelyuk M,Bhardwaj A,Addya S,Ertel A,Shoyele S,Birbe R,Salvino JM,Dicker AP,Knudsen KE,Den RB
Thu Mar 15 00:00:00 EDT 2018
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Aging cell
Liu A,Guo E,Yang J,Yang Y,Liu S,Jiang X,Hu Q,Dirsch O,Dahmen U,Zhang C,Gewirtz DA,Fang H
Thu Feb 01 00:00:00 EST 2018
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Aging cell
Liu A,Guo E,Yang J,Yang Y,Liu S,Jiang X,Hu Q,Dirsch O,Dahmen U,Zhang C,Gewirtz DA,Fang H
Thu Feb 01 00:00:00 EST 2018
Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice.
PLoS biology
Roselló-Díez A,Madisen L,Bastide S,Zeng H,Joyner AL
Fri Jun 01 00:00:00 EDT 2018
Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice.
PLoS biology
Roselló-Díez A,Madisen L,Bastide S,Zeng H,Joyner AL
Fri Jun 01 00:00:00 EDT 2018
Identification of early indicators of altered metabolism in normal development using a rodent model system.
Disease models & mechanisms
Prabakaran AD,Karakkat JV,Vijayan R,Chalissery J,Ibrahim MF,Kaimala S,Adeghate EA,Al-Marzouqi AH,Ansari SA,Mensah-Brown E,Emerald BS
Thu Mar 01 00:00:00 EST 2018
Identification of early indicators of altered metabolism in normal development using a rodent model system.
Disease models & mechanisms
Prabakaran AD,Karakkat JV,Vijayan R,Chalissery J,Ibrahim MF,Kaimala S,Adeghate EA,Al-Marzouqi AH,Ansari SA,Mensah-Brown E,Emerald BS
Thu Mar 01 00:00:00 EST 2018
Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p.
Mechanisms of ageing and development
Zhang JJ,Zhang YZ,Peng JJ,Li NS,Xiong XM,Ma QL,Luo XJ,Liu B,Peng J
Mon Jan 01 00:00:00 EST 2018
Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p.
Mechanisms of ageing and development
Zhang JJ,Zhang YZ,Peng JJ,Li NS,Xiong XM,Ma QL,Luo XJ,Liu B,Peng J
Mon Jan 01 00:00:00 EST 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.
Journal of proteome research
Yang F,Yi M,Liu Y,Wang Q,Hu Y,Deng H
Fri Mar 02 00:00:00 EST 2018
Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.
Journal of proteome research
Yang F,Yi M,Liu Y,Wang Q,Hu Y,Deng H
Fri Mar 02 00:00:00 EST 2018
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Molecular pharmaceutics
Chen X,Liu C,Zhao R,Zhao P,Wu J,Zhou N,Ying M
Mon Nov 05 00:00:00 EST 2018
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Molecular pharmaceutics
Chen X,Liu C,Zhao R,Zhao P,Wu J,Zhou N,Ying M
Mon Nov 05 00:00:00 EST 2018
LncRNA ABHD11-AS1 promotes the development of endometrial carcinoma by targeting cyclin D1.
Journal of cellular and molecular medicine
Liu Y,Wang LL,Chen S,Zong ZH,Guan X,Zhao Y
Wed Aug 01 00:00:00 EDT 2018
LncRNA ABHD11-AS1 promotes the development of endometrial carcinoma by targeting cyclin D1.
Journal of cellular and molecular medicine
Liu Y,Wang LL,Chen S,Zong ZH,Guan X,Zhao Y
Wed Aug 01 00:00:00 EDT 2018
LncRNA ABHD11-AS1 promotes the development of endometrial carcinoma by targeting cyclin D1.
Journal of cellular and molecular medicine
Liu Y,Wang LL,Chen S,Zong ZH,Guan X,Zhao Y
Wed Aug 01 00:00:00 EDT 2018
Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks.
Journal of cell science
Winkler C,Rouget R,Wu D,Beullens M,Van Eynde A,Bollen M
Mon Jul 09 00:00:00 EDT 2018
Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks.
Journal of cell science
Winkler C,Rouget R,Wu D,Beullens M,Van Eynde A,Bollen M
Mon Jul 09 00:00:00 EDT 2018
Novel role of PKR in palmitate-induced Sirt1 inactivation and endothelial cell senescence.
American journal of physiology. Heart and circulatory physiology
Li Y,Peng Z,Wang C,Li L,Leng Y,Chen R,Yuan H,Zhou S,Zhang Z,Chen AF
Sat Sep 01 00:00:00 EDT 2018
Novel role of PKR in palmitate-induced Sirt1 inactivation and endothelial cell senescence.
American journal of physiology. Heart and circulatory physiology
Li Y,Peng Z,Wang C,Li L,Leng Y,Chen R,Yuan H,Zhou S,Zhang Z,Chen AF
Sat Sep 01 00:00:00 EDT 2018
Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
American journal of physiology. Gastrointestinal and liver physiology
Hamada S,Shimosegawa T,Taguchi K,Nabeshima T,Yamamoto M,Masamune A
Mon Jan 01 00:00:00 EST 2018
Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
American journal of physiology. Gastrointestinal and liver physiology
Hamada S,Shimosegawa T,Taguchi K,Nabeshima T,Yamamoto M,Masamune A
Mon Jan 01 00:00:00 EST 2018
Comparative characterization of SHED and DPSCs during extended cultivation in vitro.
Molecular medicine reports
Wang H,Zhong Q,Yang T,Qi Y,Fu M,Yang X,Qiao L,Ling Q,Liu S,Zhao Y
Tue May 01 00:00:00 EDT 2018
Comparative characterization of SHED and DPSCs during extended cultivation in vitro.
Molecular medicine reports
Wang H,Zhong Q,Yang T,Qi Y,Fu M,Yang X,Qiao L,Ling Q,Liu S,Zhao Y
Tue May 01 00:00:00 EDT 2018
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Frontiers in cellular and infection microbiology
Wang Z,Wang Y,Wang S,Meng X,Song F,Huo W,Zhang S,Chang J,Li J,Zheng B,Liu Y,Zhang Y,Zhang W,Yu J
Fri Aug 16 00:00:00 EDT 2019
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Frontiers in cellular and infection microbiology
Wang Z,Wang Y,Wang S,Meng X,Song F,Huo W,Zhang S,Chang J,Li J,Zheng B,Liu Y,Zhang Y,Zhang W,Yu J
Fri Aug 16 00:00:00 EDT 2019
Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.
Redox biology
Masaldan S,Clatworthy SAS,Gamell C,Meggyesy PM,Rigopoulos AT,Haupt S,Haupt Y,Denoyer D,Adlard PA,Bush AI,Cater MA
Sun Apr 01 00:00:00 EDT 2018
Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.
Redox biology
Masaldan S,Clatworthy SAS,Gamell C,Meggyesy PM,Rigopoulos AT,Haupt S,Haupt Y,Denoyer D,Adlard PA,Bush AI,Cater MA
Sun Apr 01 00:00:00 EDT 2018
NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.
PloS one
Márton M,Tihanyi N,Gyulavári P,Bánhegyi G,Kapuy O
Wed May 01 00:00:00 EDT 2019
NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.
PloS one
Márton M,Tihanyi N,Gyulavári P,Bánhegyi G,Kapuy O
Wed May 01 00:00:00 EDT 2019
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Cancers
Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH
Mon Dec 31 00:00:00 EST 2018
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Cancers
Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH
Mon Dec 31 00:00:00 EST 2018
The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response.
Journal of cell science
Su Y,Wang P,Shen H,Sun Z,Xu C,Li G,Tong T,Chen J
Fri Mar 16 00:00:00 EDT 2018
Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma.
Scientific reports
Mohamed AD,Shah N,Hettmer S,Vargesson N,Wackerhage H
Tue Oct 23 00:00:00 EDT 2018
Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma.
Scientific reports
Mohamed AD,Shah N,Hettmer S,Vargesson N,Wackerhage H
Tue Oct 23 00:00:00 EDT 2018
Counteracting survival functions of EBNA3C in Epstein-Barr virus (EBV)-driven lymphoproliferative diseases by combination of SAHA and bortezomib.
Oncotarget
Hui KF,Yeung PL,Tam KP,Chiang AKS
Fri May 18 00:00:00 EDT 2018
Counteracting survival functions of EBNA3C in Epstein-Barr virus (EBV)-driven lymphoproliferative diseases by combination of SAHA and bortezomib.
Oncotarget
Hui KF,Yeung PL,Tam KP,Chiang AKS
Fri May 18 00:00:00 EDT 2018
Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells.
Cell death & disease
Sun Y,Zheng Y,Wang C,Liu Y
Mon Jul 09 00:00:00 EDT 2018
Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells.
Cell death & disease
Sun Y,Zheng Y,Wang C,Liu Y
Mon Jul 09 00:00:00 EDT 2018
Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.
Current developments in nutrition
Beaver LM,L¿hr CV,Clarke JD,Glasser ST,Watson GW,Wong CP,Zhang Z,Williams DE,Dashwood RH,Shannon J,Thuillier P,Ho E
Thu Mar 01 00:00:00 EST 2018
EZH2 inhibition sensitizes tamoxifen‑resistant breast cancer cells through cell cycle regulation.
Molecular medicine reports
Chen S,Yao F,Xiao Q,Liu Q,Yang Y,Li X,Jiang G,Kuno T,Fang Y
Thu Feb 01 00:00:00 EST 2018
Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.
Stem cells translational medicine
Harvey E,Zhang H,Sepúlveda P,Garcia SP,Sweeney D,Choudry FA,Castellano D,Thomas GN,Kattach H,Petersen R,Blake DJ,Taggart DP,Frontini M,Watt SM,Martin-Rendon E
Mon May 01 00:00:00 EDT 2017
Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.
Stem cells translational medicine
Harvey E,Zhang H,Sepúlveda P,Garcia SP,Sweeney D,Choudry FA,Castellano D,Thomas GN,Kattach H,Petersen R,Blake DJ,Taggart DP,Frontini M,Watt SM,Martin-Rendon E
Mon May 01 00:00:00 EDT 2017
H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing.
Oxidative medicine and cellular longevity
Wu W,Hou CL,Mu XP,Sun C,Zhu YC,Wang MJ,Lv QZ
Fri Mar 02 00:00:00 EST 2018
H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing.
Oxidative medicine and cellular longevity
Wu W,Hou CL,Mu XP,Sun C,Zhu YC,Wang MJ,Lv QZ
Fri Mar 02 00:00:00 EST 2018
MicroRNA let-7g inhibited hypoxia-induced proliferation of PASMCs via G0/G1 cell cycle arrest by targeting c-myc.
Life sciences
Zhang WF,Xiong YW,Zhu TT,Xiong AZ,Bao HH,Cheng XS
Wed Feb 01 00:00:00 EST 2017
MicroRNA let-7g inhibited hypoxia-induced proliferation of PASMCs via G0/G1 cell cycle arrest by targeting c-myc.
Life sciences
Zhang WF,Xiong YW,Zhu TT,Xiong AZ,Bao HH,Cheng XS
Wed Feb 01 00:00:00 EST 2017
miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.
Mechanisms of ageing and development
Zhang JJ,Liu WQ,Peng JJ,Ma QL,Peng J,Luo XJ
Thu Jun 01 00:00:00 EDT 2017
miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.
Mechanisms of ageing and development
Zhang JJ,Liu WQ,Peng JJ,Ma QL,Peng J,Luo XJ
Thu Jun 01 00:00:00 EDT 2017
Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a) in vivo are not necessarily senescent.
Cell cycle (Georgetown, Tex.)
Frescas D,Hall BM,Strom E,Virtuoso LP,Gupta M,Gleiberman AS,Rydkina E,Balan V,Vujcic S,Chernova OB,Gudkov AV
Fri Aug 18 00:00:00 EDT 2017
Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a) in vivo are not necessarily senescent.
Cell cycle (Georgetown, Tex.)
Frescas D,Hall BM,Strom E,Virtuoso LP,Gupta M,Gleiberman AS,Rydkina E,Balan V,Vujcic S,Chernova OB,Gudkov AV
Fri Aug 18 00:00:00 EDT 2017
Knockout of 4.1B triggers malignant transformation in SV40T-immortalized mouse embryo fibroblast cells.
Molecular carcinogenesis
Wang Z,Zhang J,Zeng Y,Sun S,Zhang J,Zhang B,Zhu M,Ouyang R,Ma B,Ye M,An X,Liu J
Wed Feb 01 00:00:00 EST 2017
Knockout of 4.1B triggers malignant transformation in SV40T-immortalized mouse embryo fibroblast cells.
Molecular carcinogenesis
Wang Z,Zhang J,Zeng Y,Sun S,Zhang J,Zhang B,Zhu M,Ouyang R,Ma B,Ye M,An X,Liu J
Wed Feb 01 00:00:00 EST 2017
Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress.
International journal of cardiology
Lei Y,Yang G,Hu L,Piao L,Inoue A,Jiang H,Sasaki T,Zhao G,Yisireyili M,Yu C,Xu W,Takeshita K,Okumura K,Kuzuya M,Cheng XW
Fri Sep 15 00:00:00 EDT 2017
Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress.
International journal of cardiology
Lei Y,Yang G,Hu L,Piao L,Inoue A,Jiang H,Sasaki T,Zhao G,Yisireyili M,Yu C,Xu W,Takeshita K,Okumura K,Kuzuya M,Cheng XW
Fri Sep 15 00:00:00 EDT 2017
Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys.
Journal of assisted reproduction and genetics
Yan P,Xu J,Zeng Y,Dong G,Cao H,Zheng M,Zhu H
Sat Apr 01 00:00:00 EDT 2017
Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys.
Journal of assisted reproduction and genetics
Yan P,Xu J,Zeng Y,Dong G,Cao H,Zheng M,Zhu H
Sat Apr 01 00:00:00 EDT 2017
Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging.
FEBS open bio
Xia MY,Zhao XY,Huang QL,Sun HY,Sun C,Yuan J,He C,Sun Y,Huang X,Kong W,Kong WJ
Thu Jun 01 00:00:00 EDT 2017
Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging.
FEBS open bio
Xia MY,Zhao XY,Huang QL,Sun HY,Sun C,Yuan J,He C,Sun Y,Huang X,Kong W,Kong WJ
Thu Jun 01 00:00:00 EDT 2017
Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation.
Asian Pacific journal of cancer prevention : APJCP
Tamgue O,Lei M
Wed Sep 27 00:00:00 EDT 2017
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Cell death & disease
Mao X,Li P,Wang Y,Liang Z,Liu J,Li J,Jiang Y,Bao G,Li L,Zhu B,Ren Y,Zhao X,Zhang J,Liu Y,Yang J,Liu P
Thu Jan 12 00:00:00 EST 2017
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Cell death & disease
Mao X,Li P,Wang Y,Liang Z,Liu J,Li J,Jiang Y,Bao G,Li L,Zhu B,Ren Y,Zhao X,Zhang J,Liu Y,Yang J,Liu P
Thu Jan 12 00:00:00 EST 2017
Over Expression of Long Non-Coding RNA PANDA Promotes Hepatocellular Carcinoma by Inhibiting Senescence Associated Inflammatory Factor IL8.
Scientific reports
Peng C,Hu W,Weng X,Tong R,Cheng S,Ding C,Xiao H,Lv Z,Xie H,Zhou L,Wu J,Zheng S
Fri Jun 23 00:00:00 EDT 2017
Over Expression of Long Non-Coding RNA PANDA Promotes Hepatocellular Carcinoma by Inhibiting Senescence Associated Inflammatory Factor IL8.
Scientific reports
Peng C,Hu W,Weng X,Tong R,Cheng S,Ding C,Xiao H,Lv Z,Xie H,Zhou L,Wu J,Zheng S
Fri Jun 23 00:00:00 EDT 2017
Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions.
Scientific reports
Watanabe R,Fujita N,Sato Y,Kobayashi T,Morita M,Oike T,Miyamoto K,Kuro-O M,Michigami T,Fukumoto S,Tsuji T,Toyama Y,Nakamura M,Matsumoto M,Miyamoto T
Thu Aug 10 00:00:00 EDT 2017
Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions.
Scientific reports
Watanabe R,Fujita N,Sato Y,Kobayashi T,Morita M,Oike T,Miyamoto K,Kuro-O M,Michigami T,Fukumoto S,Tsuji T,Toyama Y,Nakamura M,Matsumoto M,Miyamoto T
Thu Aug 10 00:00:00 EDT 2017
IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.
Molecular medicine reports
Ma Y,Jiang J,Zhang Y,Ding Y,Xu T,Lu B
Tue Aug 01 00:00:00 EDT 2017
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
The Journal of biological chemistry
Wang S,Cao Z,Xue J,Li H,Jiang W,Cheng Y,Li G,Zhang X
Fri May 19 00:00:00 EDT 2017
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
The Journal of biological chemistry
Wang S,Cao Z,Xue J,Li H,Jiang W,Cheng Y,Li G,Zhang X
Fri May 19 00:00:00 EDT 2017
5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1.
British journal of pharmacology
Altieri P,Murialdo R,Barisione C,Lazzarini E,Garibaldi S,Fabbi P,Ruggeri C,Borile S,Carbone F,Armirotti A,Canepa M,Ballestrero A,Brunelli C,Montecucco F,Ameri P,Spallarossa P
Wed Nov 01 00:00:00 EDT 2017
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
Biochemical and biophysical research communications
Suzuki Y,Sato T,Sugimoto M,Baskoro H,Karasutani K,Mitsui A,Nurwidya F,Arano N,Kodama Y,Hirano SI,Ishigami A,Seyama K,Takahashi K
Sat Oct 07 00:00:00 EDT 2017
Inhibition of BMI1 induces autophagy-mediated necroptosis.
Autophagy
Dey A,Mustafi SB,Saha S,Kumar Dhar Dwivedi S,Mukherjee P,Bhattacharya R
Mon Dec 26 00:00:00 EST 2016
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Stem cells international
Li WQ,Wang ZJ,Liu S,Hu Y,Yin M,Lu Y
Fri Mar 18 00:00:00 EDT 2016
N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ 1-42 via the CB2 Receptor.
Stem cells international
Li WQ,Wang ZJ,Liu S,Hu Y,Yin M,Lu Y
Fri Mar 18 00:00:00 EDT 2016
Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response.
Biochemistry
Nomanbhoy TK,Sharma G,Brown H,Wu J,Aban A,Vogeti S,Alemayehu S,Sykes M,Rosenblum JS,Kozarich JW
Tue Sep 27 00:00:00 EDT 2016
Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response.
Biochemistry
Nomanbhoy TK,Sharma G,Brown H,Wu J,Aban A,Vogeti S,Alemayehu S,Sykes M,Rosenblum JS,Kozarich JW
Tue Sep 27 00:00:00 EDT 2016
Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis.
Oncotarget
Vermeer DW,Coppock JD,Zeng E,Lee KM,Spanos WC,Onken MD,Uppaluri R,Lee JH,Vermeer PD
Tue Apr 26 00:00:00 EDT 2016
Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis.
Oncotarget
Vermeer DW,Coppock JD,Zeng E,Lee KM,Spanos WC,Onken MD,Uppaluri R,Lee JH,Vermeer PD
Tue Apr 26 00:00:00 EDT 2016
The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity.
Scientific reports
Lazzarini E,Balbi C,Altieri P,Pfeffer U,Gambini E,Canepa M,Varesio L,Bosco MC,Coviello D,Pompilio G,Brunelli C,Cancedda R,Ameri P,Bollini S
Thu Jul 21 00:00:00 EDT 2016
The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity.
Scientific reports
Lazzarini E,Balbi C,Altieri P,Pfeffer U,Gambini E,Canepa M,Varesio L,Bosco MC,Coviello D,Pompilio G,Brunelli C,Cancedda R,Ameri P,Bollini S
Thu Jul 21 00:00:00 EDT 2016
Comparison of liver oncogenic potential among human RAS isoforms.
Oncotarget
Chung SI,Moon H,Ju HL,Kim DY,Cho KJ,Ribback S,Dombrowski F,Calvisi DF,Ro SW
Tue Feb 09 00:00:00 EST 2016
Comparison of liver oncogenic potential among human RAS isoforms.
Oncotarget
Chung SI,Moon H,Ju HL,Kim DY,Cho KJ,Ribback S,Dombrowski F,Calvisi DF,Ro SW
Tue Feb 09 00:00:00 EST 2016
Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation.
Scientific reports
Xu X,Pang J,Chen Y,Bucala R,Zhang Y,Ren J
Fri Mar 04 00:00:00 EST 2016
Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation.
Scientific reports
Xu X,Pang J,Chen Y,Bucala R,Zhang Y,Ren J
Fri Mar 04 00:00:00 EST 2016
miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation.
Oncotarget
Feng T,Shao F,Wu Q,Zhang X,Xu D,Qian K,Xie Y,Wang S,Xu N,Wang Y,Qi C
Tue Mar 29 00:00:00 EDT 2016
miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation.
Oncotarget
Feng T,Shao F,Wu Q,Zhang X,Xu D,Qian K,Xie Y,Wang S,Xu N,Wang Y,Qi C
Tue Mar 29 00:00:00 EDT 2016
Antiaging Effect of Inula britannica on Aging Mouse Model Induced by D-Galactose.
Evidence-based complementary and alternative medicine : eCAM
Chen H,Long Y,Guo L
Tue Apr 12 00:00:00 EDT 2016
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
The Journal of biological chemistry
Chen Y,Pan K,Wang P,Cao Z,Wang W,Wang S,Hu N,Xue J,Li H,Jiang W,Li G,Zhang X
Fri Jun 10 00:00:00 EDT 2016
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
The Journal of biological chemistry
Chen Y,Pan K,Wang P,Cao Z,Wang W,Wang S,Hu N,Xue J,Li H,Jiang W,Li G,Zhang X
Fri Jun 10 00:00:00 EDT 2016
Mechanism of BRG1 silencing in primary cancers.
Oncotarget
Marquez-Vilendrer SB,Thompson K,Lu L,Reisman D
Tue Aug 30 00:00:00 EDT 2016
Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.
Journal of the American Heart Association
Altieri P,Barisione C,Lazzarini E,Garuti A,Bezante GP,Canepa M,Spallarossa P,Tocchetti CG,Bollini S,Brunelli C,Ameri P
Fri Jan 08 00:00:00 EST 2016
Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.
Journal of the American Heart Association
Altieri P,Barisione C,Lazzarini E,Garuti A,Bezante GP,Canepa M,Spallarossa P,Tocchetti CG,Bollini S,Brunelli C,Ameri P
Fri Jan 08 00:00:00 EST 2016
mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Cancer cell
Damsky W,Micevic G,Meeth K,Muthusamy V,Curley DP,Santhanakrishnan M,Erdelyi I,Platt JT,Huang L,Theodosakis N,Zaidi MR,Tighe S,Davies MA,Dankort D,McMahon M,Merlino G,Bardeesy N,Bosenberg M
Mon Jan 12 00:00:00 EST 2015
mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Cancer cell
Damsky W,Micevic G,Meeth K,Muthusamy V,Curley DP,Santhanakrishnan M,Erdelyi I,Platt JT,Huang L,Theodosakis N,Zaidi MR,Tighe S,Davies MA,Dankort D,McMahon M,Merlino G,Bardeesy N,Bosenberg M
Mon Jan 12 00:00:00 EST 2015
Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Aging cell
Hua Y,Robinson TJ,Cao Y,Shi GP,Ren J,Nair S
Mon Jun 01 00:00:00 EDT 2015
Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Aging cell
Hua Y,Robinson TJ,Cao Y,Shi GP,Ren J,Nair S
Mon Jun 01 00:00:00 EDT 2015
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Clinical epigenetics
Rajendran P,Dashwood WM,Li L,Kang Y,Kim E,Johnson G,Fischer KA,Löhr CV,Williams DE,Ho E,Yamamoto M,Lieberman DA,Dashwood RH
Mon Sep 21 00:00:00 EDT 2015
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Clinical epigenetics
Rajendran P,Dashwood WM,Li L,Kang Y,Kim E,Johnson G,Fischer KA,Löhr CV,Williams DE,Ho E,Yamamoto M,Lieberman DA,Dashwood RH
Mon Sep 21 00:00:00 EDT 2015
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Clinical epigenetics
Rajendran P,Dashwood WM,Li L,Kang Y,Kim E,Johnson G,Fischer KA,Löhr CV,Williams DE,Ho E,Yamamoto M,Lieberman DA,Dashwood RH
Mon Sep 21 00:00:00 EDT 2015
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Clinical epigenetics
Rajendran P,Dashwood WM,Li L,Kang Y,Kim E,Johnson G,Fischer KA,Löhr CV,Williams DE,Ho E,Yamamoto M,Lieberman DA,Dashwood RH
Mon Sep 21 00:00:00 EDT 2015
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Oncology reports
Huang W,Zhong W,Xu J,Su B,Huang G,Du J,Liu Q
Tue Sep 01 00:00:00 EDT 2015
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation.
Oncology reports
Huang W,Zhong W,Xu J,Su B,Huang G,Du J,Liu Q
Tue Sep 01 00:00:00 EDT 2015
Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction.
Oncotarget
Al-Wahab Z,Mert I,Tebbe C,Chhina J,Hijaz M,Morris RT,Ali-Fehmi R,Giri S,Munkarah AR,Rattan R
Sun May 10 00:00:00 EDT 2015
Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction.
Oncotarget
Al-Wahab Z,Mert I,Tebbe C,Chhina J,Hijaz M,Morris RT,Ali-Fehmi R,Giri S,Munkarah AR,Rattan R
Sun May 10 00:00:00 EDT 2015
Evaluation of Protein Profiles From Treated Xenograft Tumor Models Identifies an Antibody Panel for Formalin-fixed and Paraffin-embedded (FFPE) Tissue Analysis by Reverse Phase Protein Arrays (RPPA).
Molecular & cellular proteomics : MCP
Bader S,Zajac M,Friess T,Ruge E,Rieder N,Gierke B,Heubach Y,Thomas M,Pawlak M
Thu Oct 01 00:00:00 EDT 2015
Evaluation of Protein Profiles From Treated Xenograft Tumor Models Identifies an Antibody Panel for Formalin-fixed and Paraffin-embedded (FFPE) Tissue Analysis by Reverse Phase Protein Arrays (RPPA).
Molecular & cellular proteomics : MCP
Bader S,Zajac M,Friess T,Ruge E,Rieder N,Gierke B,Heubach Y,Thomas M,Pawlak M
Thu Oct 01 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Oncotarget
Jäger W,Xue H,Hayashi T,Janssen C,Awrey S,Wyatt AW,Anderson S,Moskalev I,Haegert A,Alshalalfa M,Erho N,Davicioni E,Fazli L,Li E,Collins C,Wang Y,Black PC
Fri Aug 28 00:00:00 EDT 2015
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.
Oncotarget
Jäger W,Xue H,Hayashi T,Janssen C,Awrey S,Wyatt AW,Anderson S,Moskalev I,Haegert A,Alshalalfa M,Erho N,Davicioni E,Fazli L,Li E,Collins C,Wang Y,Black PC
Fri Aug 28 00:00:00 EDT 2015
Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability.
Circulation
Wang J,Uryga AK,Reinhold J,Figg N,Baker L,Finigan A,Gray K,Kumar S,Clarke M,Bennett M
Tue Nov 17 00:00:00 EST 2015
Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1.
Investigative ophthalmology & visual science
Zhuge CC,Xu JY,Zhang J,Li W,Li P,Li Z,Chen L,Liu X,Shang P,Xu H,Lu Y,Wang F,Lu L,Xu GT
Tue May 20 00:00:00 EDT 2014
Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1.
Investigative ophthalmology & visual science
Zhuge CC,Xu JY,Zhang J,Li W,Li P,Li Z,Chen L,Liu X,Shang P,Xu H,Lu Y,Wang F,Lu L,Xu GT
Tue May 20 00:00:00 EDT 2014
BCL6 overexpression is associated with decreased p19 ARF expression and confers an independent prognosticator in gallbladder carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Liang PI,Li CF,Chen LT,Sun DP,Chen TJ,Hsing CH,Hsu HP,Lin CY
Sat Feb 01 00:00:00 EST 2014
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Notch1 signaling contributes to the oncogenic effect of HBx on human hepatic cells.
Biotechnology letters
Wang F,Xia X,Wang J,Sun Q,Luo J,Cheng B
Tue Jan 01 00:00:00 EST 2013
Notch1 signaling contributes to the oncogenic effect of HBx on human hepatic cells.
Biotechnology letters
Wang F,Xia X,Wang J,Sun Q,Luo J,Cheng B
Tue Jan 01 00:00:00 EST 2013
Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
BMC complementary and alternative medicine
Deng S,Hu B,An HM,Du Q,Xu L,Shen KP,Shi XF,Wei MM,Wu Y
Sat Jun 08 00:00:00 EDT 2013
Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
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Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
BMC complementary and alternative medicine
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Sat Jun 08 00:00:00 EDT 2013
Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
BMC complementary and alternative medicine
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Ocular expression and distribution of products of the POAG-associated chromosome 9p21 gene region.
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Ocular expression and distribution of products of the POAG-associated chromosome 9p21 gene region.
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Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells.
Human molecular genetics
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