Product References
Bavachinin protects the liver in NAFLD by promoting regeneration via targeting PCNA.
Journal of advanced research
Dong X,Lu S,Tian Y,Ma H,Wang Y,Zhang X,Sun G,Luo Y,Sun X
Mon Jan 01 00:00:00 EST 2024
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
World neurosurgery
Yidian W,Jihe K,Xudong G,Daxue Z,Mingqiang L,Xuewen K
Tue Aug 01 00:00:00 EDT 2023
The Natural Alkaloid (-)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex.
Journal of natural products
Feng L,Shang RR,Wang XJ,Li L,Li X,Gong YX,Shi LY,Wang JW,Qian ZY,Tan NH,Wang Z
Fri Jun 23 00:00:00 EDT 2023
Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs).
Stem cells international
Ling L,Shu H,Huang Y,Hou J,Hua Y
Tue Feb 28 00:00:00 EST 2023
saKLK1-374 is more difficult to induce KLK1 expression in normal prostate cell lines than that in prostate cancer cell lines: Rethinking the universality of RNA activation.
Biochemical and biophysical research communications
Zhang M,Lin D,Luo C,Wei P,Cui K,Chen K,Chen Z
Sun Feb 05 00:00:00 EST 2023
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Carcinogenesis
Jin Y,Zhao L,Wang S,Zhang X,Quan J,Lin Z,Piao J
Fri May 26 00:00:00 EDT 2023
MicroRNA-499-5p promotes vascular smooth muscle cell proliferation and migration via inhibiting SOX6.
Physiological genomics
Sheng Y,Yang Z,Feng Z,Wang Y,Ji N
Wed Feb 01 00:00:00 EST 2023
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
ACS applied materials & interfaces
Zhao X,Zhang S,Gao S,Chang HM,Leung PCK,Tan J
Wed Mar 29 00:00:00 EDT 2023
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Oncogene
Liu R,Miao J,Jia Y,Kong G,Hong F,Li F,Zhai M,Zhang R,Liu J,Xu X,Wang T,Liu H,Hu J,Yang Y,He A
Mon May 01 00:00:00 EDT 2023
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Oncogene
Liu R,Miao J,Jia Y,Kong G,Hong F,Li F,Zhai M,Zhang R,Liu J,Xu X,Wang T,Liu H,Hu J,Yang Y,He A
Mon May 01 00:00:00 EDT 2023
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Oncogene
Liu R,Miao J,Jia Y,Kong G,Hong F,Li F,Zhai M,Zhang R,Liu J,Xu X,Wang T,Liu H,Hu J,Yang Y,He A
Mon May 01 00:00:00 EDT 2023
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Oncogene
Liu R,Miao J,Jia Y,Kong G,Hong F,Li F,Zhai M,Zhang R,Liu J,Xu X,Wang T,Liu H,Hu J,Yang Y,He A
Mon May 01 00:00:00 EDT 2023
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Journal of translational medicine
Wang X,Wang J,Zhao X,Wu H,Li J,Cheng Y,Guo Q,Cao X,Liang T,Sun L,Zhang G
Fri Jun 23 00:00:00 EDT 2023
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Journal of translational medicine
Wang X,Wang J,Zhao X,Wu H,Li J,Cheng Y,Guo Q,Cao X,Liang T,Sun L,Zhang G
Fri Jun 23 00:00:00 EDT 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Environmental pollution (Barking, Essex : 1987)
Zheng Z,Halifu A,Ma J,Liu L,Fu Q,Yi B,Du E,Tian D,Xu Y,Zhang Z,Zhu J
Tue Aug 01 00:00:00 EDT 2023
SNORD6 promotes cervical cancer progression by accelerating E6-mediated p53 degradation.
Cell death discovery
Li Q,Xie B,Chen X,Lu B,Chen S,Sheng X,Zhao Y
Tue Jun 27 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Toxicology
Li M,Li T,Yin J,Xie C,Zhu J
Sun Jan 15 00:00:00 EST 2023
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Toxicology
Li M,Li T,Yin J,Xie C,Zhu J
Sun Jan 15 00:00:00 EST 2023
Oral Squamous Cell Carcinoma Cells with Acquired Resistance to Erlotinib Are Sensitive to Anti-Cancer Effect of Quercetin via Pyruvate Kinase M2 (PKM2).
Cells
Chan CY,Hong SC,Chang CM,Chen YH,Liao PC,Huang CY
Sun Jan 01 00:00:00 EST 2023
The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.
British journal of pharmacology
Zhao J,Bai D,Qi L,Cao W,Du J,Gu C,Zhou C,Gao Y,Zhang L,Zhao Y,Lu N
Sat Apr 01 00:00:00 EDT 2023
The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.
British journal of pharmacology
Zhao J,Bai D,Qi L,Cao W,Du J,Gu C,Zhou C,Gao Y,Zhang L,Zhao Y,Lu N
Sat Apr 01 00:00:00 EDT 2023
The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.
British journal of pharmacology
Zhao J,Bai D,Qi L,Cao W,Du J,Gu C,Zhou C,Gao Y,Zhang L,Zhao Y,Lu N
Sat Apr 01 00:00:00 EDT 2023
The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.
British journal of pharmacology
Zhao J,Bai D,Qi L,Cao W,Du J,Gu C,Zhou C,Gao Y,Zhang L,Zhao Y,Lu N
Sat Apr 01 00:00:00 EDT 2023
Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.
Toxicology letters
Hou Z,Yan M,Li H,Wang W,You S,Wang M,Du T,Gong H,Li W,Guo L,Wei S,Zhang B,Ji M,Chen X
Sat Apr 15 00:00:00 EDT 2023
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Leukemia research
Deng X,Zeng Y,Qiu X,Zhong M,Xiong X,Luo M,Zhang J,Chen X
Sat Jul 01 00:00:00 EDT 2023
miR-656-3p inhibits melanomas in vitro and in vivo by inducing senescence via inhibiting LMNB2.
Journal of cancer research and clinical oncology
Sun J,Lui K,Pang Q,Xu M,Zhao H,Shao J,Yu Y,Chu X,Liang Y,Xu J,Shen Z
Fri Sep 01 00:00:00 EDT 2023
Long non-coding RNA DINO promotes cisplatin sensitivity in lung adenocarcinoma via the p53-Bax axis.
Journal of thoracic disease
Liu Z,Wang Q,Bi Y,Chubarov AS,Li Y,Liu L,Yang X,Dmitrienko EV,Zheng Y
Fri Apr 28 00:00:00 EDT 2023
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway.
Cellular oncology (Dordrecht)
Wang L,Yue Y,Zhang L,Jing M,Ma M,Liu C,Li Y,Xu S,Wang K,Wang X,Fan J,Zhang M
Sun Oct 01 00:00:00 EDT 2023
Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology.
International journal of molecular sciences
Shang Z,Fan M,Zhang J,Wang Z,Jiang S,Li W
Thu May 04 00:00:00 EDT 2023
Peripheral Klotho protects the kidney and brain by regulating M2a/M2c macrophage polarization in d-gal-treated aged mice.
Tissue & cell
Wang Y,Xiong X,Wang K,Bao Y,Zhang T,Ainiwaer D,Wang G,Li H,Sun Z
Thu Jun 01 00:00:00 EDT 2023
Peripheral Klotho protects the kidney and brain by regulating M2a/M2c macrophage polarization in d-gal-treated aged mice.
Tissue & cell
Wang Y,Xiong X,Wang K,Bao Y,Zhang T,Ainiwaer D,Wang G,Li H,Sun Z
Thu Jun 01 00:00:00 EDT 2023
Silencing of LINC00467 inhibits cell proliferation in testicular germ cell tumors cells.
Biomolecules & biomedicine
Zhu F,Liu Z,Zhou Q,Zhou D,Fan J,Bo H,Fan L
Mon Sep 04 00:00:00 EDT 2023
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Journal of nanobiotechnology
Wu G,Su Q,Li J,Xue C,Zhu J,Cai Q,Huang J,Ji S,Cheng B,Ge H
Thu Jan 05 00:00:00 EST 2023
EIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p/RNF113A pathway.
Biomarker research
Yang X,Han F,Hu X,Li G,Wu H,Can C,Wei Y,Liu J,Wang R,Jia W,Ji C,Ma D
Tue Jun 06 00:00:00 EDT 2023
The Males Absent on the First (MOF) Mediated Acetylation Alters the Protein Stability and Transcriptional Activity of YY1 in HCT116 Cells.
International journal of molecular sciences
Wu T,Zhao B,Cai C,Chen Y,Miao Y,Chu J,Sui Y,Li F,Chen W,Cai Y,Wang F,Jin J
Sat May 13 00:00:00 EDT 2023
CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Cell reports
Zhou Z,Zhang H,Tao Y,Jie H,Zhao J,Zang J,Li H,Wang Y,Wang T,Zhao H,Li Y,Guo C,Zhu F,Mao H,Zhang L,Liu F,Wang Q
Tue May 30 00:00:00 EDT 2023
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma.
Aging
Hsieh TY,Sung WW,Chang YC,Yu CY,Lu LY,Dong C,Lee TH,Chen SL
Fri Apr 21 00:00:00 EDT 2023
Polo-like kinase 4 inhibitor CFI-400945 inhibits carotid arterial neointima formation but increases atherosclerosis.
Cell death discovery
Sun J,Belke D,Gui Y,Chen YX,Zhou S,Zheng XL
Tue Feb 07 00:00:00 EST 2023
Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1.
Frontiers in oncology
Yuan C,Liao Y,Liao S,Huang M,Li D,Wu W,Quan Y,Li L,Yu X,Si W
Tue Mar 28 00:00:00 EDT 2023
Simultaneous suppression of PKM2 and PHGDH elicits synergistic anti-cancer effect in NSCLC.
Frontiers in pharmacology
Wang K,Lu H,Wang X,Liu Q,Hu J,Liu Y,Jin M,Kong D
Thu Jun 08 00:00:00 EDT 2023
Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity.
BMC cancer
Gao X,Jiang P,Wei X,Zhang W,Zheng J,Sun S,Yao H,Liu X,Zhang Q
Wed Feb 15 00:00:00 EST 2023
A Comprehensive Analysis Revealing FBXW9 as a Potential Prognostic and Immunological Biomarker in Breast Cancer.
International journal of molecular sciences
Yu S,Liang Z,Fan Z,Cao B,Wang N,Wu R,Sun H
Thu Mar 09 00:00:00 EST 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Particle Debris Generated from Passenger Tires Induces Morphological and Gene Expression Alterations in the Macrophages Cell Line RAW 264.7.
Nanomaterials (Basel, Switzerland)
Poma A,Aloisi M,Bonfigli A,Colafarina S,Zarivi O,Aimola P,Vecchiotti G,Arrizza L,Di Cola A,Cesare P
Fri Feb 17 00:00:00 EST 2023
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Nature communications
Wu Y,Tang L,Huang H,Yu Q,Hu B,Wang G,Ge F,Yin T,Li S,Yu X
Fri Mar 10 00:00:00 EST 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Lycopene suppresses gastric cancer cell growth without affecting normal gastric epithelial cells.
The Journal of nutritional biochemistry
Zhou Y,Fu R,Yang M,Liu W,Tong Z
Thu Jun 01 00:00:00 EDT 2023
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Cell transplantation
Li H,Ren J,Cui H,Wang D,Zhao R,Liu X,Tian S,Wang J,Zhang J,Li P,Thorne RF,Duan S
Mon Jun 05 00:00:00 EDT 2023
RNA-sequencing analysis reveals the potential molecular mechanism of RAD54B in the proliferation of inflamed human dental pulp cells.
International endodontic journal
Huang P,Wang F,Wang X,Meng X,Qiao W,Meng L
Sun Jan 01 00:00:00 EST 2023
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Cancer gene therapy
Gong W,Guo Y,Yuan H,Chai R,Wan Z,Zheng B,Hu X,Chen B,Gao S,Dai Q,Yu P,Tu S
Thu Jun 01 00:00:00 EDT 2023
Serum response factor activates peroxidasin transcription to block senescence of hepatic stellate cells.
Life sciences
Guo Y,Zhou A,Zhang Y,Chen Y,Chen Y,Gao Y,Miao X
Fri Sep 01 00:00:00 EDT 2023
DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hou S,Cheng Y,Wang Z,Xia L,Wang J,Wang H,Sun J,Ma J,Yan Y
Sun Jan 01 00:00:00 EST 2023
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
PloS one
Zhu Y,Sun W,Jiang X,Bai R,Luo Y,Gao Y,Li S,Huang Z,Gong Y,Xie C
Fri Feb 03 00:00:00 EST 2023
Circular RNA circFBXO7 attenuates non-small cell lung cancer tumorigenesis by sponging miR-296-3p to facilitate KLF15-mediated transcriptional activation of CDKN1A.
Translational oncology
Wang ZH,Ye LL,Xiang X,Wei XS,Niu YR,Peng WB,Zhang SY,Zhang P,Xue QQ,Wang HL,Du YH,Liu Y,Ai JQ,Zhou Q
Sat Apr 01 00:00:00 EDT 2023
Circular RNA circFBXO7 attenuates non-small cell lung cancer tumorigenesis by sponging miR-296-3p to facilitate KLF15-mediated transcriptional activation of CDKN1A.
Translational oncology
Wang ZH,Ye LL,Xiang X,Wei XS,Niu YR,Peng WB,Zhang SY,Zhang P,Xue QQ,Wang HL,Du YH,Liu Y,Ai JQ,Zhou Q
Sat Apr 01 00:00:00 EDT 2023
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Cell proliferation
Tang Q,Markby GR,MacNair AJ,Tang K,Tkacz M,Parys M,Phadwal K,MacRae VE,Corcoran BM
Thu Jun 01 00:00:00 EDT 2023
Angelicin impedes the progression of glioblastoma via inactivation of YAP signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang M,Xing S,Jia J,Zeng W,Lei J,Qian Y,Xiong Z,Wang X,Cao L,Wang Y,Wang Y,Jiang Y,Huang Z
Mon May 01 00:00:00 EDT 2023
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Biomedicines
Qiu Q,Guo G,Guo X,Hu X,Yu T,Liu G,Zhang H,Chen Y,She J
Mon Mar 13 00:00:00 EDT 2023
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
Redox biology
Ma L,Li K,Wei W,Zhou J,Li Z,Zhang T,Wangsun Y,Tian F,Dong Q,Zhang H,Xing W
Thu Jun 01 00:00:00 EDT 2023
Delivery of miR-3529-3p using MnO2 -SiO2 -APTES nanoparticles combined with phototherapy suppresses lung adenocarcinoma progression by targeting HIGD1A.
Thoracic cancer
Zhang Y,Wang RR,Liu R,Xie SY,Jiao F,Li YJ,Xin J,Zhang H,Wang Z,Yan YF
Sat Apr 01 00:00:00 EDT 2023
Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53.
Discover. Oncology
Zhang Y,Guo T,Li S,Ren Z,Gao S,Lu H,Ma X,Liu D,Liu Y,Kong D,Qiu Y
Wed May 31 00:00:00 EDT 2023
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Mediators of inflammation
Liu Z,Fan Z,Wang R,Li X,Chen H,Wang J
Wed Mar 15 00:00:00 EDT 2023
Unique progerin C-terminal peptide ameliorates Hutchinson-Gilford progeria syndrome phenotype by rescuing BUBR1.
Nature aging
Zhang N,Hu Q,Sui T,Fu L,Zhang X,Wang Y,Zhu X,Huang B,Lu J,Li Z,Zhang Y
Wed Feb 01 00:00:00 EST 2023
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
The FEBS journal
Hao Z,Yuan Q,Tang H,Lei C,Chen Y,Su H,Zhang C
Tue Aug 01 00:00:00 EDT 2023
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Journal of ethnopharmacology
Duan J,Li Z,Liu E,Long H,Chen L,Yang S
Wed Nov 15 00:00:00 EST 2023
Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development.
Developmental cell
Sun XL,Chen ZH,Guo X,Wang J,Ge M,Wong SZH,Wang T,Li S,Yao M,Johnston LA,Wu QF
Mon May 08 00:00:00 EDT 2023
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Experimental gerontology
Xia G,Wen Z,Zhang L,Huang J,Wang X,Liang C,Cui X,Cao X,Wu S
Mon May 01 00:00:00 EDT 2023
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Experimental gerontology
Xia G,Wen Z,Zhang L,Huang J,Wang X,Liang C,Cui X,Cao X,Wu S
Mon May 01 00:00:00 EDT 2023
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Experimental gerontology
Xia G,Wen Z,Zhang L,Huang J,Wang X,Liang C,Cui X,Cao X,Wu S
Mon May 01 00:00:00 EDT 2023
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Experimental gerontology
Xia G,Wen Z,Zhang L,Huang J,Wang X,Liang C,Cui X,Cao X,Wu S
Mon May 01 00:00:00 EDT 2023
Interleukin-13 promotes cellular senescence through inducing mitochondrial dysfunction in IgG4-related sialadenitis.
International journal of oral science
Zhu M,Min S,Mao X,Zhou Y,Zhang Y,Li W,Li L,Wu L,Cong X,Yu G
Mon Jun 20 00:00:00 EDT 2022
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes.
BMC medicine
Gautheron J,Lima L,Akinci B,Zammouri J,Auclair M,Ucar SK,Ozen S,Altay C,Bax BE,Nemazanyy I,Lenoir V,Prip-Buus C,Acquaviva-Bourdain C,Lascols O,Fève B,Vigouroux C,Noel E,Jéru I
Mon Mar 28 00:00:00 EDT 2022
The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors.
Cell death & disease
Liu W,Zhang B,Zhang D,Guo F,Ye K,Zhu L,Jin X
Sat Apr 02 00:00:00 EDT 2022
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Cellular signalling
Hao J,Xi Y,Jiao L,Wen X,Wu R,Chang G,Sun F,Wei C,Li H
Thu Dec 01 00:00:00 EST 2022
Identification and validation of aging-related genes in COPD based on bioinformatics analysis.
Aging
Zhong S,Yang L,Liu N,Zhou G,Hu Z,Chen C,Wang Y
Tue May 24 00:00:00 EDT 2022
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Molecular oncology
Ren D,Sun Y,Li D,Wu H,Jin X
Tue Mar 01 00:00:00 EST 2022
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Cellular and molecular life sciences : CMLS
Zhou T,Chen T,Lai B,Zhang W,Luo X,Xia D,Fu W,Xu J
Mon May 02 00:00:00 EDT 2022
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Cellular and molecular life sciences : CMLS
Zhou T,Chen T,Lai B,Zhang W,Luo X,Xia D,Fu W,Xu J
Mon May 02 00:00:00 EDT 2022
lncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock wave.
Regenerative therapy
Han K,Kang N,Yu X,Lu J,Ma Y
Thu Dec 01 00:00:00 EST 2022
ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.
Cell death & disease
Geng S,Peng W,Wang X,Hu X,Liang H,Hou J,Wang F,Zhao G,Lü M,Cui H
Wed Jun 22 00:00:00 EDT 2022
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Journal of oncology
Chen X,Zhang L,Geng J,Chen Z,Cui X
Sat Jul 16 00:00:00 EDT 2022
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Frontiers in genetics
Liao H,Zhang L,Lu S,Li W,Dong W
Sat Jul 16 00:00:00 EDT 2022
Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Gao L,Yang WY,Qi H,Sun CJ,Qin XM,Du GH
Sun May 01 00:00:00 EDT 2022
Knockdown of LMNB1 Inhibits the Proliferation of Lung Adenocarcinoma Cells by Inducing DNA Damage and Cell Senescence.
Frontiers in oncology
Li J,Sun Z,Cui Y,Qin L,Wu F,Li Y,Du N,Li X
Sat Jul 16 00:00:00 EDT 2022
Long noncoding RNA HOXC-AS3 interacts with CDK2 to promote proliferation in hepatocellular carcinoma.
Biomarker research
Su C,Wang W,Mo J,Liu F,Zhang H,Liu Y,Chen X,Liao Z,Zhang B,Zhu P
Sun Aug 28 00:00:00 EDT 2022
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Frontiers in molecular biosciences
Zou P,Zhang X,Zhang R,Chai X,Zhao Y,Li E,Zhang Q,Yan R,Yang J,Liao B
Sat Apr 09 00:00:00 EDT 2022
Analysis of regulating activities of 5'-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo.
Frontiers in pharmacology
Wang X,Luo X,Gan X,Chen C,Yang Z,Wen J,Fang W,Huang H,Gao C,Zhou X,Feng X,Liu Y
Tue Aug 30 00:00:00 EDT 2022
Stachydrine hydrochloride inhibits hepatocellular carcinoma progression via LIF/AMPK axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Bao X,Liu Y,Huang J,Yin S,Sheng H,Han X,Chen Q,Wang T,Chen S,Qiu Y,Zhang C,Yu H
Wed Jun 01 00:00:00 EDT 2022
RSL1D1 modulates cell senescence and proliferation via regulation of PPARγ mRNA stability.
Life sciences
Jiang Z,Hao F,Zhu F,Yuan F,Ma L,Li G,Chen J,Tong T
Sat Oct 15 00:00:00 EDT 2022
Bioactive Vitamin D Attenuates MED28-Mediated Cell Growth and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells.
BioMed research international
Huang CY,Weng YT,Hsieh NT,Li PC,Lee TY,Li CI,Liu HS,Lee MF
Fri Sep 09 00:00:00 EDT 2022
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Acta pharmacologica Sinica
Zhang B,Liu ZY,Wu R,Zhang CM,Cao K,Shan WG,Liu Z,Ji M,Tian ZL,Sethi G,Shi HL,Wang RH
Mon Aug 01 00:00:00 EDT 2022
Alteration of E2F2 Expression in Governing Endothelial Cell Senescence.
Genes
Liu H,Chen L,Xiao W,Liu J,Long C,Zhan W,Cui C,Yang L,Chen S
Wed Aug 24 00:00:00 EDT 2022
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Cell death & disease
Zheng ZY,Chu MY,Lin W,Zheng YQ,Xu XE,Chen Y,Liao LD,Wu ZY,Wang SH,Li EM,Xu LY
Wed May 25 00:00:00 EDT 2022
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Cell death & disease
Zheng ZY,Chu MY,Lin W,Zheng YQ,Xu XE,Chen Y,Liao LD,Wu ZY,Wang SH,Li EM,Xu LY
Wed May 25 00:00:00 EDT 2022
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Frontiers in oncology
Wang H,Chen Y,Yuan Q,Chen L,Dai P,Li X
Tue Jan 03 00:00:00 EST 2023
LncRNA LYPLAL1-AS1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional MIRLET7B inactivation.
Cell & bioscience
Yang Y,Liu S,He C,Lv T,Zeng L,Zhang F,Chen H,Zhao RC
Thu Apr 21 00:00:00 EDT 2022
SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α.
Cellular oncology (Dordrecht)
Cui X,Wang Y,Lan W,Wang S,Cui Y,Zhang X,Lin Z,Piao J
Tue Feb 01 00:00:00 EST 2022
1,25(OH)2D3 Mitigates Oxidative Stress-Induced Damage to Nucleus Pulposus-Derived Mesenchymal Stem Cells through PI3K/Akt Pathway.
Oxidative medicine and cellular longevity
Wang JW,Zhu L,Shi PZ,Wang PC,Dai Y,Wang YX,Lu XH,Cheng XF,Feng XM,Zhang L
Mon Apr 04 00:00:00 EDT 2022
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou X,Wang W,Li Z,Chen L,Wen C,Ruan Q,Xu Z,Liu R,Xu J,Bai Y,Deng J
Sat Jan 01 00:00:00 EST 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 EDT 2022
NOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance.
Cell death discovery
Shi J,Chen SY,Shen XT,Yin XK,Zhao WW,Bai SM,Feng WX,Feng LL,Qin C,Zheng J,Wang YL,Fan XJ
Mon Oct 31 00:00:00 EDT 2022
DEAD-box helicase 56 functions as an oncogene promote cell proliferation and invasion in gastric cancer via the FOXO1/p21 Cip1/c-Myc signaling pathway.
Bioengineered
Wang J,Wang Y,Wang J,Zhang S,Yu Z,Zheng K,Fu Z,Wang C,Huang W,Chen J
Sun May 01 00:00:00 EDT 2022
3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells.
Pharmaceutics
Santarelli R,Pompili C,Gilardini Montani MS,Evangelista L,Gonnella R,Cirone M
Thu Mar 17 00:00:00 EDT 2022
Rg1 Protects Hematopoietic Stem Cells from LiCl-Induced Oxidative Stress via Wnt Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Wang Z,Xia J,Li J,Chen L,Chen X,Zhang Y,Wang L,Wang Y
Fri Apr 08 00:00:00 EDT 2022
Grp94 Inhibitor HCP1 Inhibits Human Dermal Fibroblast Senescence.
Genes
Cui X,Hao X,Wen J,Zhang S,Zhao B,Miao J
Wed Sep 14 00:00:00 EDT 2022
Osteoblastic protein kinase D1 contributes to the prostate cancer cells dormancy via GAS6-circadian clock signaling.
Biochimica et biophysica acta. Molecular cell research
Li G,Fan M,Zheng Z,Zhang Y,Zhang Z,Huang Z,Luo W,Zhao W,Lai X,Chen H,Zeng F,Deng F
Thu Sep 01 00:00:00 EDT 2022
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary.
GeroScience
Hense JD,Garcia DN,Isola JV,Alvarado-Rincón JA,Zanini BM,Prosczek JB,Stout MB,Mason JB,Walsh PT,Brieño-Enríquez MA,Schadock I,Barros CC,Masternak MM,Schneider A
Wed Jun 01 00:00:00 EDT 2022
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Molecules (Basel, Switzerland)
Zhang W,Yang X,Liu J,Pan Y,Zhang M,Chen L
Mon Sep 12 00:00:00 EDT 2022
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Oncogene
Zheng X,Liu Z,Zhong J,Zhou L,Chen J,Zheng L,Li Z,Zhang R,Pan J,Wu Y,Liu Z,Kang T
Fri Jul 01 00:00:00 EDT 2022
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Oncogene
Zheng X,Liu Z,Zhong J,Zhou L,Chen J,Zheng L,Li Z,Zhang R,Pan J,Wu Y,Liu Z,Kang T
Fri Jul 01 00:00:00 EDT 2022
The serum soluble Klotho alleviates cardiac aging and regulates M2a/M2c macrophage polarization via inhibiting TLR4/Myd88/NF-κB pathway.
Tissue & cell
Wang Y,Wang K,Bao Y,Zhang T,Ainiwaer D,Xiong X,Wang G,Sun Z
Wed Jun 01 00:00:00 EDT 2022
The serum soluble Klotho alleviates cardiac aging and regulates M2a/M2c macrophage polarization via inhibiting TLR4/Myd88/NF-κB pathway.
Tissue & cell
Wang Y,Wang K,Bao Y,Zhang T,Ainiwaer D,Xiong X,Wang G,Sun Z
Wed Jun 01 00:00:00 EDT 2022
Novel microtubule inhibitor SQ overcomes multidrug resistance in MCF-7/ADR cells by inhibiting BCRP function and mediating apoptosis.
Toxicology and applied pharmacology
Chang X,Liu Z,Cao S,Bian J,Zheng D,Wang N,Guan Q,Wu Y,Zhang W,Li Z,Zuo D
Tue Feb 01 00:00:00 EST 2022
Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma.
Journal of experimental & clinical cancer research : CR
Chen ZW,Hu JF,Wang ZW,Liao CY,Kang FP,Lin CF,Huang Y,Huang L,Tian YF,Chen S
Sat Apr 23 00:00:00 EDT 2022
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
Aging cell
Long C,Liu H,Zhan W,Chen L,Yu Z,Tian S,Xiang Y,Chen S,Tian XL
Thu Sep 01 00:00:00 EDT 2022
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
Aging cell
Long C,Liu H,Zhan W,Chen L,Yu Z,Tian S,Xiang Y,Chen S,Tian XL
Thu Sep 01 00:00:00 EDT 2022
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
Aging cell
Long C,Liu H,Zhan W,Chen L,Yu Z,Tian S,Xiang Y,Chen S,Tian XL
Thu Sep 01 00:00:00 EDT 2022
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.
Aging cell
Long C,Liu H,Zhan W,Chen L,Yu Z,Tian S,Xiang Y,Chen S,Tian XL
Thu Sep 01 00:00:00 EDT 2022
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Food & function
Lu H,Yin H,Qu L,Ma X,Fu R,Fan D
Mon Apr 04 00:00:00 EDT 2022
HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
International journal of biological sciences
Zhang Z,Wu Q,Fang M,Liu Y,Jiang J,Feng Q,Hu R,Xu J
Thu Jun 02 00:00:00 EDT 2022
Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis.
Frontiers in immunology
Liu Y,Song X,Li C,Hu H,Li W,Wang L,Hu J,Liao C,Liang H,He Z,Ye L
Tue Apr 19 00:00:00 EDT 2022
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Frontiers in pharmacology
Hu Z,Wang Y,Gao X,Zhang Y,Liu C,Zhai Y,Chang X,Li H,Li Y,Lou J,Li C
Sat Sep 17 00:00:00 EDT 2022
SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis.
Disease markers
Zhou X,Lin L,Qi Y,Xu M,Xu Q,Wang Y,Qu J
Tue Aug 16 00:00:00 EDT 2022
Oridonin Delays Aging Through the AKT Signaling Pathway.
Frontiers in pharmacology
An Y,Zhu J,Wang X,Sun X,Luo C,Zhang Y,Ye Y,Li X,Abulizi A,Huang Z,Zhang H,Yang B,Xie Z
Sat Jul 16 00:00:00 EDT 2022
Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation.
Frontiers in pharmacology
Liu M,Hu T,Gou W,Chang H,Li Y,Li Y,Zuo D,Hou W,Jiao S
Fri Feb 17 00:00:00 EST 2023
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
EBioMedicine
Jyothula SSK,Peters A,Liang Y,Bi W,Shivshankar P,Yau S,Garcha PS,Yuan X,Akkanti B,Collum S,Wareing N,Thandavarayan RA,Poli de Frias F,Rosas IO,Zhao B,Buja LM,Eltzschig HK,Huang HJ,Karmouty-Quintana H
Thu Dec 01 00:00:00 EST 2022
Identification of 3-Phenylquinoline Derivative PQ1 as an Antagonist of p53 Transcriptional Activity.
ACS omega
Wu X,Wang L,Li Z
Tue Nov 29 00:00:00 EST 2022
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H2S in Diabetes.
Aging and disease
Xi Y,Wen X,Zhang Y,Jiao L,Bai S,Shi S,Chang G,Wu R,Sun F,Hao J,Li H
Wed Jun 01 00:00:00 EDT 2022
Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma.
Frontiers in oncology
Zhu T,Wang T,Feng Z,Gao F,Zhang J,Jin C,Tian H,Xu J,Chen H,Ou Q,Wang J,Xu G,Lu L
Fri Jul 22 00:00:00 EDT 2022
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Archives of gerontology and geriatrics
Cabral VLF,Wang F,Peng X,Gao J,Zhou Z,Sun R,Bao J,Wu X
Tue Jul 12 00:00:00 EDT 2022
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging.
Theranostics
Lazzarini E,Lodrini AM,Arici M,Bolis S,Vagni S,Panella S,Rendon-Angel A,Saibene M,Metallo A,Torre T,Vassalli G,Ameri P,Altomare C,Rocchetti M,Barile L
Mon Jul 18 00:00:00 EDT 2022
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Jiang Z,Jiang C,Jin L,Chen Z,Feng Z,Jiang X,Cao Y
Sat Oct 01 00:00:00 EDT 2022
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Frontiers in molecular biosciences
Liang Z,Miao Y,Teng X,Xiao L,Guo Q,Xue H,Tian D,Jin S,Wu Y
Tue Aug 09 00:00:00 EDT 2022
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
Cells
Huang Z,Gan S,Zhuang X,Chen Y,Lu L,Wang Y,Qi X,Feng Q,Huang Q,Du B,Zhang R,Liu Z
Tue Aug 09 00:00:00 EDT 2022
CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation.
Cell death and differentiation
Zhang P,Gao K,Zhang L,Sun H,Zhao X,Liu Y,Lv Z,Shi Q,Chen Y,Jiao D,Li Y,Gu W,Wang C
Fri Apr 01 00:00:00 EDT 2022
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
Renal failure
He S,Zhou M,Zheng H,Wang Y,Wu S,Gao Y,Chen J
Thu Dec 01 00:00:00 EST 2022
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
Chemico-biological interactions
Jiang S,Jiang T,Huang H,Chen X,Li L,Wang Z,Fei J,Liu C,Liu Z,Cheng Y
Wed Jan 05 00:00:00 EST 2022
Circadian clock gene BMAL1 inhibits the proliferation and tumor-formation ability of nasopharyngeal carcinoma cells and increases the sensitivity of radiotherapy.
Chronobiology international
Zhao C,Meng X,Li Y,Liu L,He Q,Jiang J,Chen Y,Li X,Li Y,Tang Y,Zhou D,Zhou J,Jin F
Sat Oct 01 00:00:00 EDT 2022
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.
Cell death & disease
Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X
Wed Jul 13 00:00:00 EDT 2022
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.
Cell death & disease
Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X
Wed Jul 13 00:00:00 EDT 2022
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.
Cell death & disease
Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X
Wed Jul 13 00:00:00 EDT 2022
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.
Cell death & disease
Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X
Wed Jul 13 00:00:00 EDT 2022
Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells.
Cell death & disease
Zhang M,Peng R,Wang H,Yang Z,Zhang H,Zhang Y,Wang M,Wang H,Lin J,Zhao Q,Liu J
Thu Feb 17 00:00:00 EST 2022
CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis.
Molecular cancer
Hua J,Wang X,Ma L,Li J,Cao G,Zhang S,Lin W
Mon Jun 06 00:00:00 EDT 2022
l-Asparaginase synergizes with etoposide via the PI3K/Akt/mTOR pathway in Epstein-Barr virus-positive Burkitt lymphoma.
Journal of biochemical and molecular toxicology
Sang W,Tu D,Zhang M,Qin Y,Yin W,Song X,Sun C,Yan D,Wang X,Zeng L,Li Z,Xu K,Xu L
Mon Aug 01 00:00:00 EDT 2022
Effects of Low-Intensity Pulsed Ultrasound on the Migration and Homing of Human Amnion-Derived Mesenchymal Stem Cells to Ovaries in Rats With Premature Ovarian Insufficiency.
Cell transplantation
Ling L,Hou J,Wang Y,Shu H,Huang Y
Wed Oct 26 00:00:00 EDT 2022
Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation.
Frontiers in oncology
Bi JH,Jiang YH,Ye SJ,Wu MR,Yi Y,Wang HX,Wang LM
Tue Aug 23 00:00:00 EDT 2022
Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification.
Oxidative medicine and cellular longevity
Lin T,Yang WQ,Luo WW,Zhang LL,Mai YQ,Li ZQ,Liu ST,Jiang LJ,Liu PQ,Li ZM
Tue Aug 23 00:00:00 EDT 2022
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Human cell
Li H,Xu J,Zhang Y,Hong L,He Z,Zeng Z,Zhang L
Tue Nov 01 00:00:00 EDT 2022
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Human cell
Li H,Xu J,Zhang Y,Hong L,He Z,Zeng Z,Zhang L
Tue Nov 01 00:00:00 EDT 2022
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Human cell
Li H,Xu J,Zhang Y,Hong L,He Z,Zeng Z,Zhang L
Tue Nov 01 00:00:00 EDT 2022
Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy.
Human cell
Li H,Xu J,Zhang Y,Hong L,He Z,Zeng Z,Zhang L
Tue Nov 01 00:00:00 EDT 2022
MiR-205-5p promotes lung cancer progression and is valuable for the diagnosis of lung cancer.
Thoracic cancer
Zhao YL,Zhang JX,Yang JJ,Wei YB,Peng JF,Fu CJ,Huang MH,Wang R,Wang PY,Sun GB,Xie SY
Tue Mar 01 00:00:00 EST 2022
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Biology direct
Peng T,Liu M,Hu L,Guo D,Wang D,Qi B,Ren G,Hu C,Zhang F,Chun HJ,Song L,Hu J,Li Y
Wed Nov 16 00:00:00 EST 2022
Aldolase A promotes cell proliferation and cisplatin resistance via the EGFR pathway in gastric cancer.
American journal of translational research
Gu M,Jiang B,Li H,Zhu D,Jiang Y,Xu W
Wed Oct 19 00:00:00 EDT 2022
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Life sciences
Xu M,Ren L,Fan J,Huang L,Zhou L,Li X,Ye X
Tue Feb 01 00:00:00 EST 2022
Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells.
International journal of molecular sciences
Huang TT,Chen CM,Lan YW,Lin SS,Choo KB,Chong KY
Mon Nov 28 00:00:00 EST 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation.
Biochimica et biophysica acta. Molecular basis of disease
Zhou Y,Yang Z,Zhang H,Li H,Zhang M,Wang H,Zhang M,Qiu P,Zhang R,Liu J
Fri Apr 01 00:00:00 EDT 2022
Canine Mammary Tumor Cell Lines Derived from Metastatic Foci Show Increased RAD51 Expression but Diminished Radioresistance via p21 Inhibition.
Veterinary sciences
Shimakawa K,Ochiai K,Hirose S,Tanabe E,Michishita M,Sakaue M,Yoshikawa Y,Morimatsu M,Tajima T,Watanabe M,Tanaka Y
Sat Dec 17 00:00:00 EST 2022
PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence.
The Prostate
Singh CK,Denu RA,Nihal M,Shabbir M,Garvey DR,Huang W,Iczkowski KA,Ahmad N
Wed Jun 01 00:00:00 EDT 2022
CCDC106 promotes the proliferation and invasion of ovarian cancer cells by suppressing p21 transcription through a p53-independent pathway.
Bioengineered
Zhao N,Wang C,Guo P,Hou J,Yang H,Lan T,Zhou Y,Li J,Bhawal UK,Liu Y
Fri Apr 01 00:00:00 EDT 2022
Eltanexor Effectively Reduces Viability of Glioblastoma and Glioblastoma Stem-Like Cells at Nano-Molar Concentrations and Sensitizes to Radiotherapy and Temozolomide.
Biomedicines
Otte K,Zhao K,Braun M,Neubauer A,Raifer H,Helmprobst F,Barrera FO,Nimsky C,Bartsch JW,Rusch T
Wed Aug 31 00:00:00 EDT 2022
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
Materials today. Bio
Fu Z,Du H,Meng S,Yao M,Zhao P,Li X,Zheng X,Yuan Z,Yang H,Cai K,Dai L
Thu Dec 01 00:00:00 EST 2022
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
Experimental dermatology
Zhou S,Li P,Qin L,Huang S,Dang N
Sat Oct 01 00:00:00 EDT 2022
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
International journal of molecular sciences
Xu J,Shi P,Xia F,Zhao X,Chen J,Geng R,Cui H,Yang L
Mon Oct 10 00:00:00 EDT 2022
Bisphenol A exposure causes testicular toxicity by targeting DPY30-mediated post-translational modification of PI3K/AKT signaling in mice.
Ecotoxicology and environmental safety
He H,Li X,Shen J,Bai S,Li C,Shi H
Thu Sep 15 00:00:00 EDT 2022
EXOSC5 promotes proliferation of gastric cancer through regulating AKT/STAT3 signaling pathways.
Journal of Cancer
Chen X,Huang Y,Liu J,Lin W,Chen C,Chen Y,Ding Y,Yang Y,Chen Y,Wang H,Teng L
Tue Apr 05 00:00:00 EDT 2022
Avenanthramide C induces cellular senescence in colorectal cancer cells via suppressing β-catenin-mediated the transcription of miR-183/96/182 cluster.
Biochemical pharmacology
Fu R,Dou Z,Li N,Zhang J,Li Z,Yang P
Sun May 01 00:00:00 EDT 2022
ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity.
Science advances
Xiao FH,Yu Q,Deng ZL,Yang K,Ye Y,Ge MX,Yan D,Wang HT,Chen XQ,Yang LQ,Yang BY,Lin R,Zhang W,Yang XL,Dong L,He Y,Zhou J,Cai WW,Li J,Kong QP
Fri Apr 29 00:00:00 EDT 2022
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Stem cells international
Wang X,Li Y,Li Y,Liu P,Liu S,Pan Y
Sat Feb 04 00:00:00 EST 2023
Caveolin-1 Regulation and Function in Mouse Uterus during Early Pregnancy and under Human In Vitro Decidualization.
International journal of molecular sciences
Song Z,Li B,Li M,Luo J,Hong Y,He Y,Chen S,Yang Z,Liang C,Yang Z
Mon Mar 28 00:00:00 EDT 2022
An assembly-inducing PDC enabling the efficient nuclear delivery of nucleic acid for cancer stem-like cell suppression.
Nanoscale
Wang D,Tian Y,Zhang Y,Sun X,Wu Y,Liu R,Zeng F,Du J,Hu K
Thu Oct 27 00:00:00 EDT 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Bioengineered
Sun J,Chen X,Ji X,Meng S,Wang W,Wang P,Bai J,Li Z,Chen Y
Tue Mar 01 00:00:00 EST 2022
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Bioengineered
Sun J,Chen X,Ji X,Meng S,Wang W,Wang P,Bai J,Li Z,Chen Y
Tue Mar 01 00:00:00 EST 2022
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Bioengineered
Sun J,Chen X,Ji X,Meng S,Wang W,Wang P,Bai J,Li Z,Chen Y
Tue Mar 01 00:00:00 EST 2022
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Bioengineered
Sun J,Chen X,Ji X,Meng S,Wang W,Wang P,Bai J,Li Z,Chen Y
Tue Mar 01 00:00:00 EST 2022
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Dong S,Liang S,Cheng Z,Zhang X,Luo L,Li L,Zhang W,Li S,Xu Q,Zhong M,Zhu J,Zhang G,Hu S
Sat Jan 08 00:00:00 EST 2022
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Biochimica et biophysica acta. Molecular cell research
Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L
Tue Feb 01 00:00:00 EST 2022
High expression of 14-3-3¿ indicates poor prognosis and progression of lung adenocarcinoma.
Oncology letters
Feng J,Leng J,Zhao C,Guo J,Chen Y,Li H
Fri Jul 01 00:00:00 EDT 2022
The Role of RAD6B and PEDF in Retinal Degeneration.
Neuroscience
Ye Q,Wang J,Liu X,Liu Z,BaZong L,Ma J,Shen R,Ye W,Zhang W,Wang D
Sat Jan 01 00:00:00 EST 2022
The exon 12-containing LHX6 isoforms promote cervical cancer cell proliferation by regulating the MAPK signaling pathway.
Cancer medicine
Wang L,Zhou Y,Cao C,Lin S,Zhi W,Zhang D,Li J,Wei R,Jiang G,Xu H,Wang X,Xi L,Wu P
Sat Oct 01 00:00:00 EDT 2022
Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy.
Analytical cellular pathology (Amsterdam)
Yin P,Chen J,Wu Y,Gao F,Wen J,Zhang W,Su Y,Zhang X
Tue Oct 18 00:00:00 EDT 2022
Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy.
Analytical cellular pathology (Amsterdam)
Yin P,Chen J,Wu Y,Gao F,Wen J,Zhang W,Su Y,Zhang X
Tue Oct 18 00:00:00 EDT 2022
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan JH,Xu MM,Zhou LM,Gui ZW,Huang L,Li XG,Ye XL
Tue Feb 01 00:00:00 EST 2022
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
Cell death & disease
Li P,Lin Q,Sun S,Yang N,Xia Y,Cao S,Zhang W,Li Q,Guo H,Zhu M,Wang Y,Zheng Z,Li S
Wed Sep 21 00:00:00 EDT 2022
PKC signal amplification suppresses non-small cell lung cancer growth by promoting p21 expression and phosphorylation.
Heliyon
Liu S,Zhang Y,Yang Q,Zhang Y,Liu H,Huang MH,Wang R,Lu F
Thu Sep 01 00:00:00 EDT 2022
Overexpression of MLF1IP promotes colorectal cancer cell proliferation through BRCA1/AKT/p27 signaling pathway.
Cellular signalling
Xu Y,Zhang L,Wang Q,Zheng M
Fri Apr 01 00:00:00 EDT 2022
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cells
Cui X,Pei X,Wang H,Feng P,Qin H,Liu S,Yan Q,Liu J
Thu Oct 06 00:00:00 EDT 2022
Suppression of AGTR1 Induces Cellular Senescence in Hepatocellular Carcinoma Through Inactivating ERK Signaling.
Frontiers in bioengineering and biotechnology
Wang H,Cui Y,Gong H,Xu J,Huang S,Tang A
Tue Aug 02 00:00:00 EDT 2022
Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1.
Frontiers in pharmacology
Liang D,Li Z,Feng Z,Yuan Z,Dai Y,Wu X,Zhang F,Wang Y,Zhou Y,Liu L,Shi M,Xiao Y,Guo B
Sat Jul 16 00:00:00 EDT 2022
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Chemico-biological interactions
Tan J,Sun M,Yin J,Zhou Q,Zhao R,Chen Q,Sun H,Jiang C,Li S,He Y
Thu Dec 01 00:00:00 EST 2022
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Bioactive materials
Luo L,Gong J,Wang Z,Liu Y,Cao J,Qin J,Zuo R,Zhang H,Wang S,Zhao P,Yang D,Zhang M,Wang Y,Zhang J,Zhou Y,Li C,Ni B,Tian Z,Liu M
Thu Sep 01 00:00:00 EDT 2022
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.
Regenerative therapy
Morita K,Nakamura A,Machida M,Kawasaki T,Nakanishi R,Ichida J,Iwata T,Umezawa A,Akutsu H
Thu Dec 01 00:00:00 EST 2022
Elimination of Senescent Cells by Senolytics Facilitates Bony Endplate Microvessel Formation and Mitigates Disc Degeneration in Aged Mice.
Frontiers in cell and developmental biology
Chen B,Zhu R,Hu H,Zhan M,Wang T,Huang F,Wei F,Chai Y,Ling Z,Zou X
Tue Jul 26 00:00:00 EDT 2022
Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H2O2 through the microRNA-34a/SIRT1 pathway.
Scientific reports
Zhang L,Guo Y,Shi S,Zhuge Y,Chen N,Ding Z,Jin B
Tue Feb 01 00:00:00 EST 2022
Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells.
In vitro cellular & developmental biology. Animal
Miao Y,Wan W,Zhu K,Pan M,Zhao X,Ma B,Wei Q
Tue Mar 01 00:00:00 EST 2022
Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency.
Journal of ovarian research
Li J,Peng T,Wang L,Long P,Quan R,Tan H,Zeng M,Wu X,Yang J,Xiao H,Shi X
Mon Feb 28 00:00:00 EST 2022
PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Zhang Z,Huang Y,Xu N,Wang J,Yao T,Xu Y,Qiao D,Gao J,Shen S,Ma J
Tue Apr 05 00:00:00 EDT 2022
Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.
Nature communications
Yuan K,Li Z,Kuang W,Wang X,Ji M,Chen W,Ding J,Li J,Min W,Sun C,Ye X,Lu M,Wang L,Ge H,Jiang Y,Hao H,Xiao Y,Yang P
Wed May 25 00:00:00 EDT 2022
Comparative analysis of mouse embryonic palatal mesenchymal cells isolated by two primary culture methods.
Tissue & cell
Wang X,Peng X,Chen J,Wang Y,Zhao X,Li T,Du J
Wed Jun 01 00:00:00 EDT 2022
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Journal of advanced research
Tai S,Sun J,Zhou Y,Zhu Z,He Y,Chen M,Yang H,Xiao Y,Tu T,Tang L,Li X,Zeng J,Zheng X,Zhou S
Tue Nov 01 00:00:00 EDT 2022
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Journal of advanced research
Tai S,Sun J,Zhou Y,Zhu Z,He Y,Chen M,Yang H,Xiao Y,Tu T,Tang L,Li X,Zeng J,Zheng X,Zhou S
Tue Nov 01 00:00:00 EDT 2022
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Journal of advanced research
Tai S,Sun J,Zhou Y,Zhu Z,He Y,Chen M,Yang H,Xiao Y,Tu T,Tang L,Li X,Zeng J,Zheng X,Zhou S
Tue Nov 01 00:00:00 EDT 2022
Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.
Journal of advanced research
Tai S,Sun J,Zhou Y,Zhu Z,He Y,Chen M,Yang H,Xiao Y,Tu T,Tang L,Li X,Zeng J,Zheng X,Zhou S
Tue Nov 01 00:00:00 EDT 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 EDT 2022
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy.
Aging cell
Sun J,Li Y,Yang X,Dong W,Yang J,Hu Q,Zhang C,Fang H,Liu A
Sat Jan 01 00:00:00 EST 2022
A novel 3'tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer.
Cell death & disease
Cui H,Li H,Wu H,Du F,Xie X,Zeng S,Zhang Z,Dong K,Shang L,Jing C,Li L
Wed May 18 00:00:00 EDT 2022
KIF22 Promotes Development of Pancreatic Cancer by Regulating the MEK/ERK/P21 Signaling Axis.
BioMed research international
Zhang R,Ma L,Wei Y,Wei K,Song T,Du Z,Feng Z
Wed May 18 00:00:00 EDT 2022
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Cell death discovery
Zhang G,Zhu Q,Yan X,Ci M,Zhao E,Hou J,Wan S,Lü M,Cui H
Sat Apr 09 00:00:00 EDT 2022
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Placenta
Chen X,Song QL,Ji R,Wang JY,Li ZH,Guo D,Yin TL,Wang SJ,Yang J
Tue Feb 01 00:00:00 EST 2022
Tetrahydroxy stilbene glucoside alters neurogenesis and neuroinflammation to ameliorate radiation-associated cognitive disability via AMPK/Tet2.
International immunopharmacology
Miao BB,Gao D,Hao JP,Li YL,Li L,Wang JB,Xiao XH,Yang CC,Zhang L
Thu Sep 01 00:00:00 EDT 2022
Identification and Validation of Ferroptosis-Related Biomarkers in Septic Cardiomyopathy via Bioinformatics Analysis.
Frontiers in genetics
Gong CW,Yuan MM,Qiu BQ,Wang LJ,Zou HX,Hu T,Lai SQ,Liu JC
Sat Jul 16 00:00:00 EDT 2022
Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization.
Cell death & disease
Liu H,Zhao D,Li H,Zhang W,Lin Q,Wang X,Zheng S,Zhang L,Li L,Hu S,Hu Y
Mon Feb 21 00:00:00 EST 2022
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
International journal of molecular sciences
Zhang Y,Ma P,Duan Z,Liu Y,Mi Y,Fan D
Fri Feb 11 00:00:00 EST 2022
Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.
Journal of cellular and molecular medicine
Cheng Y,Hu Y,Wang H,Zhao Z,Jiang X,Zhang Y,Zhang J,Tong Y,Qiu X
Sun Aug 01 00:00:00 EDT 2021
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
American journal of translational research
Zhang JJ,Song CG,Dai JM,Zhang XQ,Lin P,Li L,Yang XM,Chen ZN
Tue Jun 22 00:00:00 EDT 2021
Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.
Endokrynologia Polska
Li X,He J,Li X,Li Y,Zhou Y,Cai S
Mon Mar 28 00:00:00 EDT 2022
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Cell death discovery
Li P,Liu X,Zhao T,Li F,Wang Q,Zhang P,Hirayama R,Chen W,Jin X,Zheng X,Wang Z,Li Q
Tue Jul 20 00:00:00 EDT 2021
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Journal of cellular and molecular medicine
Zhang J,Yang S,Guan H,Zhou J,Gao Y
Mon Feb 01 00:00:00 EST 2021
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Frontiers in physiology
Fan S,Wang C,Huang K,Liang M
Wed Feb 23 00:00:00 EST 2022
Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation.
Journal of cellular physiology
Osana S,Kitajima Y,Suzuki N,Nunomiya A,Takada H,Kubota T,Murayama K,Nagatomi R
Thu Jul 01 00:00:00 EDT 2021
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Nature metabolism
Chen W,Yu X,Wu Y,Tang J,Yu Q,Lv X,Zha Z,Hu B,Li X,Chen J,Ma L,Workman JL,Li S
Thu Jul 01 00:00:00 EDT 2021
LncRNA ENSG00000254615 Modulates Proliferation and 5-FU Resistance by Regulating p21 and Cyclin D1 in Colorectal Cancer.
Cancer investigation
Fu Y,Huang R,Li J,Xie X,Deng Y
Fri Oct 01 00:00:00 EDT 2021
Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation.
Oncology reports
Jia M,Su B,Mo L,Qiu W,Ying J,Lin P,Yang B,Li D,Wang D,Xu L,Li H,Zhou Z,Li X,Li J
Mon Mar 01 00:00:00 EST 2021
Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling.
Toxicology letters
Xu X,Sun X,Wan X,Chen X,Jiang X
Mon Nov 01 00:00:00 EDT 2021
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
iScience
Su CH,Liao WJ,Ke WC,Yang RB,Tarn WY
Fri Nov 19 00:00:00 EST 2021
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Frontiers in oncology
Sanches JGP,Song B,Zhang Q,Cui X,Yabasin IB,Ntim M,Li X,He J,Zhang Y,Mao J,Lu Y,Li L
Fri Apr 02 00:00:00 EDT 2021
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Cell death discovery
Li P,Cao S,Huang Y,Zhang Y,Liu J,Cai X,Zhou L,Li J,Jiang Z,Ding L,Zheng Z,Li S,Ye Q
Thu Jul 29 00:00:00 EDT 2021
eIF3a R803K mutation mediates chemotherapy resistance by inducing cellular senescence in small cell lung cancer.
Pharmacological research
Chen YX,Wang CJ,Xiao DS,He BM,Li M,Yi XP,Zhang W,Yin JY,Liu ZQ
Wed Dec 01 00:00:00 EST 2021
NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Experimental cell research
Zhao X,Jiang L,Hu D,Tang Y,Zhao G,Du X,Luo S,Tang W
Tue Jun 15 00:00:00 EDT 2021
Morphologic Analysis of Urinary Podocytes in Focal Segmental Glomerulosclerosis.
Kidney360
Shirai Y,Miura K,Yokoyama T,Horita S,Nakayama H,Seino H,Ando T,Shiratori A,Yabuuchi T,Kaneko N,Ishiwa S,Ishizuka K,Hara M,Hattori M
Thu Mar 25 00:00:00 EDT 2021
METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Journal of cellular and molecular medicine
Wang XK,Zhang YW,Wang CM,Li B,Zhang TZ,Zhou WJ,Cheng LJ,Huo MY,Zhang CH,He YL
Thu Jul 01 00:00:00 EDT 2021
Ropivacaine Induces Cell Cycle Arrest in the G0/G1 Phase and Apoptosis of PC12 Cells via Inhibiting Mitochondrial STAT3 Translocation.
Inflammation
Zeng L,Li A,Zhang Z,Zhang F,Chen H,Wang Y,Ding X,Luo H
Wed Dec 01 00:00:00 EST 2021
Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells.
Translational oncology
Zhao A,Zhang J,Liu Y,Jia X,Lu X,Wang Q,Ji T,Yang L,Xue J,Gao R,Yu Y,Yang A
Fri Oct 01 00:00:00 EDT 2021
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Carcinogenesis
Huang Y,Lin Y,Song X,Wu D
Fri May 28 00:00:00 EDT 2021
Fangchinoline Inhibits Human Esophageal Cancer by Transactivating ATF4 to Trigger Both Noxa-Dependent Intrinsic and DR5-Dependent Extrinsic Apoptosis.
Frontiers in oncology
Zhang Y,Wang S,Chen Y,Zhang J,Yang J,Xian J,Li L,Zhao H,Hoffman RM,Zhang Y,Jia L
Fri Jul 02 00:00:00 EDT 2021
Kojic acid enhances the proliferation of human corneal epithelial cells via p38 and p21 signaling pathways.
European journal of ophthalmology
Wei X,Du L,Sun L,Wang C,Song F,Qian H,Li X,Guo X,Tang X,Liu P
Wed Sep 01 00:00:00 EDT 2021
HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.
Journal of cellular and molecular medicine
Chen Q,Wang Y,Jiao F,Cao P,Shi C,Pei M,Wang L,Gong Z
Sun Aug 01 00:00:00 EDT 2021
Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.
Journal of agricultural and food chemistry
Wu H,Cui M,Li C,Li H,Dai Y,Cui K,Li Z
Wed Mar 17 00:00:00 EDT 2021
Lycorine hydrochloride inhibits melanoma cell proliferation, migration and invasion via down-regulating p21Cip1/WAF1.
American journal of cancer research
Shi S,Li C,Zhang Y,Deng C,Tan M,Pan G,Du J,Ji Y,Li Q,Liang H,Liu W,Guo L,Zhao G,Liu Y,Cui H
Sat Nov 11 00:00:00 EST 2023
Lycorine hydrochloride inhibits melanoma cell proliferation, migration and invasion via down-regulating p21Cip1/WAF1.
American journal of cancer research
Shi S,Li C,Zhang Y,Deng C,Tan M,Pan G,Du J,Ji Y,Li Q,Liang H,Liu W,Guo L,Zhao G,Liu Y,Cui H
Sat Nov 11 00:00:00 EST 2023
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Nutrition and cancer
Hu Z,Wang H,Fu Y,Ma K,Ma X,Wang J
Wed Sep 08 00:00:00 EDT 2021
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2.
Cell & bioscience
Wu X,Yu M,Zhang Z,Leng F,Ma Y,Xie N,Lu F
Mon Feb 08 00:00:00 EST 2021
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Cell death & disease
Xiang T,Yuan C,Guo X,Wang H,Cai Q,Xiang Y,Luo W,Liu G
Thu Feb 04 00:00:00 EST 2021
YTHDC1-mediated VPS25 regulates cell cycle by targeting JAK-STAT signaling in human glioma cells.
Cancer cell international
Zhu X,Yang H,Zhang M,Wu X,Jiang L,Liu X,Lv K
Sat Dec 04 00:00:00 EST 2021
Chemopreventive effects of pterostilbene through p53 and cell cycle in mouse lung of squamous cell carcinoma model.
Scientific reports
Surien O,Ghazali AR,Masre SF
Wed Jul 21 00:00:00 EDT 2021
N6-methyladenosine regulates ATM expression and downstream signaling.
Journal of Cancer
Zhang X,Liu P,Zheng X,Wang J,Peng Q,Li Z,Wei L,Liu C,Wu Y,Wen Y,Yan Q,Ma J
Fri Nov 05 00:00:00 EDT 2021
Canine Papillomavirus 2 E6 Does Not Interfere With UVB-Induced Upregulation of p53 and p53-Regulated Genes.
Frontiers in veterinary science
Quinlan S,May S,Weeks R,Yuan H,Luff J
Tue Apr 20 00:00:00 EDT 2021
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
ACS chemical neuroscience
Gao L,Zheng WG,Wu XK,Du GH,Qin XM
Wed Jul 07 00:00:00 EDT 2021
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Science advances
Cao P,Yang A,Li P,Xia X,Han Y,Zhou G,Wang R,Yang F,Li Y,Zhang Y,Cui Y,Ji H,Lu L,He F,Zhou G
Sun Aug 01 00:00:00 EDT 2021
CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer.
Journal of hematology & oncology
Chen S,Yang C,Wang ZW,Hu JF,Pan JJ,Liao CY,Zhang JQ,Chen JZ,Huang Y,Huang L,Zhan Q,Tian YF,Shen BY,Wang YD
Tue Apr 13 00:00:00 EDT 2021
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Cell death & disease
Luo W,Li J,Li Z,Lin T,Zhang L,Yang W,Mai Y,Liu R,Chen M,Dai C,Yang H,Lu J,Li H,Guan G,Huang M,Liu P,Li Z
Mon Jul 26 00:00:00 EDT 2021
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
BMC cancer
Jiao X,Wang B,Feng C,Song S,Tian B,Zhou C,Gao X,Sun W,Liu P
Wed Jun 30 00:00:00 EDT 2021
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
International journal of biological sciences
Bai M,Cui M,Li M,Yao X,Wu Y,Zheng L,Sun L,Song Q,Wang S,Liu L,Yu C,Huang Y
Tue Feb 22 00:00:00 EST 2022
Suppression of TCAB1 expression induced cellular senescence by lessening proteasomal degradation of p21 in cancer cells.
Cancer cell international
Niu J,Gao RQ,Cui MT,Zhang CG,Li ST,Cheng S,Ding W
Thu Jan 07 00:00:00 EST 2021
SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Stem cell reviews and reports
Liao X,Wu C,Shao Z,Zhang S,Zou Y,Wang K,Ha Y,Xing J,Zheng A,Shen Z,Zheng S,Guo J,Jie W
Sun Aug 01 00:00:00 EDT 2021
Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell-Derived Exosomes on the Senescence of Nucleus Pulposus Cells.
Orthopaedic surgery
Chen CC,Chen J,Wang WL,Xie L,Shao CQ,Zhang YX
Thu Apr 01 00:00:00 EDT 2021
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Free radical biology & medicine
Jia R,Yang F,Yan P,Ma L,Yang L,Li L
Tue Jun 01 00:00:00 EDT 2021
Adenomatous Polyposis Coli loss controls cell cycle regulators and response to paclitaxel in MDA-MB-157 metaplastic breast cancer cells.
PloS one
Astarita EM,Maloney SM,Hoover CA,Berkeley BJ,VanKlompenberg MK,Nair TM,Prosperi JR
Tue Nov 30 00:00:00 EST 2021
Fumonisin B1 Inhibits Cell Proliferation and Decreases Barrier Function of Swine Umbilical Vein Endothelial Cells.
Toxins
Li Q,Yuan Q,Wang T,Zhan Y,Yang L,Fan Y,Lei H,Su J
Fri Dec 03 00:00:00 EST 2021
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Frontiers in oncology
Wen D,Liu WL,Lu ZW,Cao YM,Ji QH,Wei WJ
Sun May 23 00:00:00 EDT 2021
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
eLife
Gautheron J,Morisseau C,Chung WK,Zammouri J,Auclair M,Baujat G,Capel E,Moulin C,Wang Y,Yang J,Hammock BD,Cerame B,Phan F,Fève B,Vigouroux C,Andreelli F,Jeru I
Tue Aug 03 00:00:00 EDT 2021
PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma.
Frontiers in oncology
Liu Y,Chen H,Li X,Zhang F,Kong L,Wang X,Bai J,Wu X
Tue Mar 16 00:00:00 EDT 2021
TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer.
Frontiers in oncology
Zhang D,Lu P,Zhu K,Wu H,Dai Y
Tue Nov 23 00:00:00 EST 2021
Identification and characterization of R2TP in the development of oral squamous cell carcinoma.
Biochemical and biophysical research communications
Kiguchi T,Kakihara Y,Yamazaki M,Katsura K,Izumi K,Tanuma JI,Saku T,Takagi R,Saeki M
Fri Apr 09 00:00:00 EDT 2021
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis.
Virologica Sinica
Li P,Jiang H,Peng H,Zeng W,Zhong Y,He M,Xie L,Chen J,Guo D,Wu J,Li CM
Wed Dec 01 00:00:00 EST 2021
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Biomedicines
Yu M,Hu X,Yan J,Wang Y,Lu F,Chang J
Fri Sep 17 00:00:00 EDT 2021
Premature senescence of placental decidua cells as a possible cause of miscarriage produced by mycophenolic acid.
Journal of biomedical science
de la Torre P,Fernández-de la Torre M,Flores AI
Mon Jan 04 00:00:00 EST 2021
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Life sciences
Chen J,Zhang W,Pan C,Fan J,Zhong X,Tang S
Thu Apr 15 00:00:00 EDT 2021
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Journal of Cancer
Zhang B,Zhang Y,Jiang X,Su H,Wang Q,Wudu M,Jiang J,Ren H,Xu Y,Liu Z,Qiu X
Fri Jan 15 00:00:00 EST 2021
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Apoptosis : an international journal on programmed cell death
Liu X,Gu Y,Bian Y,Cai D,Li Y,Zhao Y,Zhang Z,Xue M,Zhang L
Thu Apr 01 00:00:00 EDT 2021
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
International journal of molecular sciences
Wang S,Xu X,Che D,Fan R,Gao M,Cao Y,Ge C,Feng Y,Li J,Xie S,Wang C,Dai F,Gao L,Wang Y
Tue Oct 12 00:00:00 EDT 2021
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling.
Cancer cell international
Chen Y,Hong H,Wang Q,Li J,Zhang W,Chen T,Li P
Sat Nov 27 00:00:00 EST 2021
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
EMBO reports
Wu G,Suo C,Yang Y,Shen S,Sun L,Li ST,Zhou Y,Yang D,Wang Y,Cai Y,Wang N,Zhang H,Yang YG,Cao J,Gao P
Wed Mar 03 00:00:00 EST 2021
SHCBP1 interacting with EOGT enhances O-GlcNAcylation of NOTCH1 and promotes the development of pancreatic cancer.
Genomics
Yang C,Hu JF,Zhan Q,Wang ZW,Li G,Pan JJ,Huang L,Liao CY,Huang Y,Tian YF,Shen BY,Chen JZ,Wang YD,Chen S
Mon Mar 01 00:00:00 EST 2021
SHCBP1 interacting with EOGT enhances O-GlcNAcylation of NOTCH1 and promotes the development of pancreatic cancer.
Genomics
Yang C,Hu JF,Zhan Q,Wang ZW,Li G,Pan JJ,Huang L,Liao CY,Huang Y,Tian YF,Shen BY,Chen JZ,Wang YD,Chen S
Mon Mar 01 00:00:00 EST 2021
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
Journal of oncology
Li X,An M,Gao Z
Wed Dec 15 00:00:00 EST 2021
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Aging
Ding J,Zhang R,Li H,Ji Q,Cheng X,Thorne RF,Hondermarck H,Liu X,Shen C
Tue Apr 06 00:00:00 EDT 2021
Comparison of biological and transcriptomic effects of conventional cigarette and electronic cigarette smoke exposure at toxicological dose in BEAS-2B cells.
Ecotoxicology and environmental safety
Wang L,Wang Y,Chen J,Yang XM,Jiang XT,Liu P,Li M
Fri Oct 01 00:00:00 EDT 2021
MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.
Frontiers in medicine
Song H,Zhuang L,Xu X,Shi J,Hu W,Liu Z,Shi S
Tue Dec 21 00:00:00 EST 2021
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients.
Stem cell research & therapy
Ren S,Xiong H,Chen J,Yang X,Liu Y,Guo J,Jiang T,Xu Z,Yuan M,Liu Y,Zhou N,Chen H,Li W,Machens HG,Chen Z
Sat May 29 00:00:00 EDT 2021
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Oncology letters
Du T,Wang D,Wan X,Xu J,Xiao Q,Liu B
Thu Jul 01 00:00:00 EDT 2021
Two loss-of-function ANKRD11 variants in Chinese patients with short stature and a possible molecular pathway.
American journal of medical genetics. Part A
Zhang T,Yang Y,Yin X,Wang X,Ni J,Dong Z,Li C,Lu W
Mon Mar 01 00:00:00 EST 2021
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
The journal of gene medicine
Wu J,Li Y,Liu J,Xu Y
Mon Mar 01 00:00:00 EST 2021
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
Oncogenesis
Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L
Fri Dec 03 00:00:00 EST 2021
A novel histone deacetylase inhibitor LT-548-133-1 induces apoptosis by inhibiting HDAC and interfering with microtubule assembly in MCF-7 cells.
Investigational new drugs
Xue J,Wu G,Ejaz U,Akhtar F,Wan X,Zhu Y,Geng A,Chen Y,He S
Fri Oct 01 00:00:00 EDT 2021
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Cell death & disease
Tao Y,Zhang J,Chen L,Liu X,Yao M,Zhang H
Tue May 18 00:00:00 EDT 2021
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Journal of medicinal chemistry
Zhang J,Zou L,Shi D,Liu J,Zhang J,Zhao R,Wang G,Zhang L,Ouyang L,Liu B
Thu Oct 14 00:00:00 EDT 2021
Combined Treatment of Cinobufotalin and Gefitinib Exhibits Potent Efficacy against Lung Cancer.
Evidence-based complementary and alternative medicine : eCAM
Han Y,Ma R,Cao G,Liu H,He L,Tang L,Li H,Luo Q
Tue Jun 15 00:00:00 EDT 2021
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Mechanisms of ageing and development
Zhong H,Zhou Z,Guo L,Liu F,Zheng B,Bi S,Tian C
Mon Mar 01 00:00:00 EST 2021
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Drug design, development and therapy
Ding L,Ren C,Yang L,Wu Z,Li F,Jiang D,Zhu Y,Lu J
Thu Nov 04 00:00:00 EDT 2021
Characterization of Kinesin Family Member 2C as a Proto-Oncogene in Cervical Cancer.
Frontiers in pharmacology
Yang J,Wu Z,Yang L,Jeong JH,Zhu Y,Lu J,Wang B,Wang N,Wang Y,Shen K,Li R
Wed Feb 16 00:00:00 EST 2022
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
Molecular medicine reports
Chang L,Zhou R,He Y,Meng M,Hu J,Liu Y,Pan Y,Tang Z,Yue Z
Sun Aug 01 00:00:00 EDT 2021
Activity Components from Gynostemma pentaphyllum for Preventing Hepatic Fibrosis and of Its Molecular Targets by Network Pharmacology Approach.
Molecules (Basel, Switzerland)
Zhang Y,Shi G,Luo Z,Wang J,Wu S,Zhang X,Zhao Y
Tue May 18 00:00:00 EDT 2021
BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
Aging
Shao Y,Zhao C,Pan J,Zeng C,Zhang H,Liu L,Fan K,Liu X,Luo B,Fang H,Bai X,Zhang H,Cai D
Fri Mar 19 00:00:00 EDT 2021
BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
Aging
Shao Y,Zhao C,Pan J,Zeng C,Zhang H,Liu L,Fan K,Liu X,Luo B,Fang H,Bai X,Zhang H,Cai D
Fri Mar 19 00:00:00 EDT 2021
Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas.
Molecular therapy oncolytics
Wei QT,Liu BY,Ji HY,Lan YF,Tang WH,Zhou J,Zhong XY,Lian CL,Huang QZ,Wang CY,Xu YM,Guo HB
Fri Sep 24 00:00:00 EDT 2021
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
International journal of biological sciences
Bai R,Yuan C,Sun W,Zhang J,Luo Y,Gao Y,Li Y,Gong Y,Xie C
Fri Mar 25 00:00:00 EDT 2022
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Stem cells international
Zhang S,Zhang R,Qiao P,Ma X,Lu R,Wang F,Li C,E L,Liu H
Sat Jan 30 00:00:00 EST 2021
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Cancer biology & medicine
Lyu G,Su P,Hao X,Chen S,Ren S,Zhao Z,Gong Y,Liu Q,Shao C
Mon Feb 15 00:00:00 EST 2021
Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.
Frontiers in oncology
Cheng Y,Wang G,Zhao L,Dai S,Han J,Hu X,Zhou C,Wang F,Ma H,Li B,Meng Z
Wed Dec 15 00:00:00 EST 2021
Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments.
Frontiers in genetics
Zhao J,Yu SZ,Cai Q,Ma D,Jiang L,Yang LP,Yu ZY
Sun Apr 24 00:00:00 EDT 2022
Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments.
Frontiers in genetics
Zhao J,Yu SZ,Cai Q,Ma D,Jiang L,Yang LP,Yu ZY
Sun Apr 24 00:00:00 EDT 2022
FOXO1 mediates hypoxia-induced G0/G1 arrest in ovarian somatic granulosa cells by activating the TP53INP1-p53-CDKN1A pathway.
Development (Cambridge, England)
Li C,Liu Z,Wu G,Zang Z,Zhang JQ,Li X,Tao J,Shen M,Liu H
Thu Jul 15 00:00:00 EDT 2021
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6.
Biomaterials science
Xie Q,Liu Y,Long Y,Wang Z,Jiang S,Ahmed R,Daniyal M,Li B,Liu B,Wang W
Wed Apr 21 00:00:00 EDT 2021
Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Molecular medicine reports
Mao S,Jin J,Li Z,Yang W
Mon Feb 01 00:00:00 EST 2021
The Interaction of the Senescent and Adjacent Breast Cancer Cells Promotes the Metastasis of Heterogeneous Breast Cancer Cells through Notch Signaling.
International journal of molecular sciences
Zhang N,Ji J,Zhou D,Liu X,Zhang X,Liu Y,Xiang W,Wang M,Zhang L,Wang G,Huang B,Lu J,Zhang Y
Fri Jan 15 00:00:00 EST 2021
CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway.
International journal of biological sciences
Zhao S,Zhang Y,Lu X,Ding H,Han B,Song X,Miao H,Cui X,Wei S,Liu W,Chen S,Wang J
Tue Feb 22 00:00:00 EST 2022
PDRG1 predicts a poor prognosis and facilitates the proliferation and metastasis of colorectal cancer.
Experimental cell research
Xu Y,Liu J,Jiang T,Shi L,Shang L,Song J,Li L
Wed Dec 15 00:00:00 EST 2021
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Cell proliferation
Chen L,Mei G,Jiang C,Cheng X,Li D,Zhao Y,Chen H,Wan C,Yao P,Gao C,Tang Y
Tue Jun 01 00:00:00 EDT 2021
Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer.
OncoTargets and therapy
Wang G,Wang X,Han M,Wang X
Wed Apr 20 00:00:00 EDT 2022
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
International journal of molecular sciences
Chen C,Wang YS,Zhang ET,Li GA,Liu WY,Li Y,Jin YH
Mon Dec 06 00:00:00 EST 2021
A novel mutation in PCK2 gene causes primary angle-closure glaucoma.
Aging
Xu M,Yang J,Sun J,Xing X,Liu Z,Liu T
Thu Oct 14 00:00:00 EDT 2021
PRRSV Promotes MARC-145 Cells Entry Into S Phase of the Cell Cycle to Facilitate Viral Replication via Degradation of p21 by nsp11.
Frontiers in veterinary science
Wen X,Ge X,Zhou L,Zhang Y,Guo X,Yang H
Wed Apr 21 00:00:00 EDT 2021
Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury.
Antioxidants (Basel, Switzerland)
Dai C,Li H,Wang Y,Tang S,Velkov T,Shen J
Fri Jun 18 00:00:00 EDT 2021
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Frontiers in pharmacology
Yang M,Li WY,Xie J,Wang ZL,Wen YL,Zhao CC,Tao L,Li LF,Tian Y,Sheng J
Sat May 08 00:00:00 EDT 2021
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Canadian journal of physiology and pharmacology
Zhang L,Zheng J,Tie X,Lin T,Yang W,Li Z,Zou Y,Guan G,Liu P,Luo W,Li Z
Wed Sep 01 00:00:00 EDT 2021
Piezo type mechanosensitive ion channel component 1 facilitates gastric cancer omentum metastasis.
Journal of cellular and molecular medicine
Wang X,Cheng G,Miao Y,Qiu F,Bai L,Gao Z,Huang Y,Dong L,Niu X,Wang X,Li Y,Tang H,Xu Y,Song X
Mon Feb 01 00:00:00 EST 2021
Piezo type mechanosensitive ion channel component 1 facilitates gastric cancer omentum metastasis.
Journal of cellular and molecular medicine
Wang X,Cheng G,Miao Y,Qiu F,Bai L,Gao Z,Huang Y,Dong L,Niu X,Wang X,Li Y,Tang H,Xu Y,Song X
Mon Feb 01 00:00:00 EST 2021
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
Cell death & disease
Shen X,Wu C,Lei M,Yan Q,Zhang H,Zhang L,Wang X,Yang Y,Li J,Zhu Y,Chen L
Fri Apr 30 00:00:00 EDT 2021
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Stem cell research & therapy
Liu J,He J,Ge L,Xiao H,Huang Y,Zeng L,Jiang Z,Lu M,Hu Z
Thu Jul 22 00:00:00 EDT 2021
Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.
Journal of ethnopharmacology
Li L,Wang J,Feng L,Fan J,Wang J,Tan N,Wang Z
Wed Sep 15 00:00:00 EDT 2021
Dlx5 promotes cancer progression through regulation of CCND1 in oral squamous cell carcinoma (OSCC).
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zhang J,Wu J,Chen Y,Zhang W
Sun Aug 01 00:00:00 EDT 2021
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Frontiers in oncology
Wang D,Li Z,Yin H
Tue Dec 07 00:00:00 EST 2021
Integrated multiomics analysis identifies molecular landscape perturbations during hyperammonemia in skeletal muscle and myotubes.
The Journal of biological chemistry
Welch N,Singh SS,Kumar A,Dhruba SR,Mishra S,Sekar J,Bellar A,Attaway AH,Chelluboyina A,Willard BB,Li L,Huo Z,Karnik SS,Esser K,Longworth MS,Shah YM,Davuluri G,Pal R,Dasarathy S
Wed Sep 01 00:00:00 EDT 2021
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Song AN,Yin XJ,Gao P,Tang H,Meng XF,Zhang C
Mon Nov 01 00:00:00 EDT 2021
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Journal of experimental & clinical cancer research : CR
Zhang M,Wang L,Yue Y,Zhang L,Liu T,Jing M,Liang X,Ma M,Xu S,Wang K,Wang X,Fan J
Thu Feb 11 00:00:00 EST 2021
Ubiquitination of p21 by E3 Ligase TRIM21 Promotes the Proliferation of Human Neuroblastoma Cells.
Neuromolecular medicine
Wang F,Wu Z,Li Q,Ni Z,Wang C,Lu J
Wed Dec 01 00:00:00 EST 2021
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Aging
Pei Z,Yang C,Guo Y,Dong M,Wang F
Tue Sep 14 00:00:00 EDT 2021
Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies.
Science signaling
Pereira EJ,Burns JS,Lee CY,Marohl T,Calderon D,Wang L,Atkins KA,Wang CC,Janes KA
Tue Apr 14 00:00:00 EDT 2020
Voltage-gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation.
FEBS letters
Li S,Han J,Guo G,Sun Y,Zhang T,Zhao M,Xu Y,Cui Y,Liu Y,Zhang J
Sat Feb 01 00:00:00 EST 2020
Enhanced Effect of IL-1β-Activated Adipose-Derived MSCs (ADMSCs) on Repair of Intestinal Ischemia-Reperfusion Injury via COX-2-PGE2 Signaling.
Stem cells international
Liu L,He YR,Liu SJ,Hu L,Liang LC,Liu DL,Liu L,Zhu ZQ
Mon Sep 28 00:00:00 EDT 2020
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Cell proliferation
Hao Y,Huang Y,Chen J,Li J,Yuan Y,Wang M,Han L,Xin X,Wang H,Lin D,Peng F,Yu F,Zheng C,Shen C
Sat Aug 01 00:00:00 EDT 2020
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.
Molecular cancer
Jin X,Ge LP,Li DQ,Shao ZM,Di GH,Xu XE,Jiang YZ
Mon May 11 00:00:00 EDT 2020
Caloric restriction alleviates aging-related fibrosis of kidney through downregulation of miR-21 in extracellular vesicles.
Aging
Liu JR,Cai GY,Ning YC,Wang JC,Lv Y,Guo YN,Fu B,Hong Q,Sun XF,Chen XM
Thu Aug 27 00:00:00 EDT 2020
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.
Antioxidants (Basel, Switzerland)
Wang L,Zhan J,Huang W
Sat Nov 28 00:00:00 EST 2020
Combined treatment of mitoxantrone sensitizes breast cancer cells to rapalogs through blocking eEF-2K-mediated activation of Akt and autophagy.
Cell death & disease
Guan Y,Jiang S,Ye W,Ren X,Wang X,Zhang Y,Yin M,Wang K,Tao Y,Yang J,Cao D,Cheng Y
Tue Nov 03 00:00:00 EST 2020
Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics.
International journal of molecular sciences
Honda Y,Huang A,Tanaka T,Han X,Gao B,Liu H,Wang X,Zhao J,Hashimoto Y,Yamamoto K,Matsumoto N,Baba S,Umeda M
Sat Jun 13 00:00:00 EDT 2020
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
Life sciences
Pan S,Wu W,Ren F,Li L,Li Y,Li W,Wang A,Liu D,Dong Y
Sun Mar 01 00:00:00 EST 2020
Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism.
Aging
Xiang QY,Tian F,Du X,Xu J,Zhu LY,Guo LL,Wen T,Liu YS,Liu L
Wed Dec 09 00:00:00 EST 2020
Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer.
European journal of medicinal chemistry
Wei M,Xie M,Zhang Z,Wei Y,Zhang J,Pan H,Li B,Wang J,Song Y,Chong C,Zhao R,Wang J,Yu L,Yang G,Yang C
Sun Nov 15 00:00:00 EST 2020
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Journal of Cancer
Zhang YY,Luo LM,Wang YX,Zhu N,Zhao TJ,Qin L
Mon Sep 28 00:00:00 EDT 2020
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
Biotechnology letters
Zhao J,Han Y,Wang Z,Zhang R,Wang G,Mao Y
Tue Dec 01 00:00:00 EST 2020
Loss of RAD6B induces degeneration of the cochlea in mice.
Biochemical and biophysical research communications
Ma Y,Song Y,Shen R,Li P,Ding H,Guo Z,Liu X,Wang D
Tue Oct 20 00:00:00 EDT 2020
Loss of RAD6B induces degeneration of the cochlea in mice.
Biochemical and biophysical research communications
Ma Y,Song Y,Shen R,Li P,Ding H,Guo Z,Liu X,Wang D
Tue Oct 20 00:00:00 EDT 2020
UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.
Cell death & disease
Gu C,Zhao K,Zhou N,Liu F,Xie F,Yu S,Feng Y,Chen L,Yang J,Tian F,Jiang G
Thu Sep 10 00:00:00 EDT 2020
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Biochemical pharmacology
Deng X,Zhao J,Qu L,Duan Z,Fu R,Zhu C,Fan D
Sat Aug 01 00:00:00 EDT 2020
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Journal of experimental & clinical cancer research : CR
Yang Y,Wang Q,Song D,Zen R,Zhang L,Wang Y,Yang H,Zhang D,Jia J,Zhang J,Wang J
Tue Sep 22 00:00:00 EDT 2020
Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down-regulation of c-Met.
The Kaohsiung journal of medical sciences
Chen JJ,Sun X,Mao QQ,Jiang XY,Zhao XG,Xu WJ,Zhong L
Sun Mar 01 00:00:00 EST 2020
All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer.
Biotechnology letters
Dou Y,Huang D,Zeng X,Zhou Y,Jiang X,Yue C,He J,Xiao S
Mon Jun 01 00:00:00 EDT 2020
Kinesin family members KIF2C/4A/10/11/14/18B/20A/23 predict poor prognosis and promote cell proliferation in hepatocellular carcinoma.
American journal of translational research
Li X,Huang W,Huang W,Wei T,Zhu W,Chen G,Zhang J
Mon Sep 28 00:00:00 EDT 2020
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Journal of hazardous materials
Liu H,Zhang W,Fang Y,Yang H,Tian L,Li K,Lai W,Bian L,Lin B,Liu X,Xi Z
Mon Jun 15 00:00:00 EDT 2020
TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents.
Experimental and therapeutic medicine
Yang H,Chen Y,Jiang Y,Wang D,Yan J,Zhou Z
Sat Aug 01 00:00:00 EDT 2020
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Life sciences
Zeng ZM,Du HY,Xiong L,Zeng XL,Zhang P,Cai J,Huang L,Liu AW
Sun Mar 01 00:00:00 EST 2020
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
Molecular therapy oncolytics
Wu C,Guo E,Ming J,Sun W,Nie X,Sun L,Peng S,Luo M,Liu D,Zhang L,Mei Q,Long G,Hu G,Hu G
Fri Jun 26 00:00:00 EDT 2020
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21.
Molecular therapy oncolytics
Wu C,Guo E,Ming J,Sun W,Nie X,Sun L,Peng S,Luo M,Liu D,Zhang L,Mei Q,Long G,Hu G,Hu G
Fri Jun 26 00:00:00 EDT 2020
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Journal of experimental & clinical cancer research : CR
Hu Z,Long T,Ma Y,Zhu J,Gao L,Zhong Y,Wang X,Wang X,Li Z
Tue May 05 00:00:00 EDT 2020
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Cancer medicine
Wei X,Yang X,Wang B,Yang Y,Fang Z,Yi C,Shi L,Song D
Wed Jan 01 00:00:00 EST 2020
BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses.
PLoS pathogens
Wang J,Li GL,Ming SL,Wang CF,Shi LJ,Su BQ,Wu HT,Zeng L,Han YQ,Liu ZH,Jiang DW,Du YK,Li XD,Zhang GP,Yang GY,Chu BB
Sun Mar 01 00:00:00 EST 2020
Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail‑induced epithelial‑mesenchymal transition.
Molecular medicine reports
Zeng Q,Zhang Y,Zhang W,Guo Q
Mon Jun 01 00:00:00 EDT 2020
KIF15 contributes to cell proliferation and migration in breast cancer.
Human cell
Gao X,Zhu L,Lu X,Wang Y,Li R,Jiang G
Thu Oct 01 00:00:00 EDT 2020
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Experimental cell research
Osana S,Kitajima Y,Suzuki N,Xu Y,Murayama K,Nagatomi R
Tue Dec 01 00:00:00 EST 2020
The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1.
The Journal of biological chemistry
Ullah K,Chen S,Lu J,Wang X,Liu Q,Zhang Y,Long Y,Hu Z,Xu G
Fri Apr 03 00:00:00 EDT 2020
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
PLoS biology
He X,Li M,Yu H,Liu G,Wang N,Yin C,Tu Q,Narla G,Tao Y,Cheng S,Yin H
Tue Dec 01 00:00:00 EST 2020
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Oncology letters
Zhang Y,Cui N,Zheng G
Sun Mar 01 00:00:00 EST 2020
Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells.
Oncology letters
Shi B,Xu FF,Xiang CP,Jia R,Yan CH,Ma SQ,Wang N,Wang AJ,Fan P
Sun Nov 01 00:00:00 EDT 2020
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
Cancer cell international
Wu J,Su HK,Yu ZH,Xi SY,Guo CC,Hu ZY,Qu Y,Cai HP,Zhao YY,Zhao HF,Chen FR,Huang YF,To ST,Feng BH,Sai K,Chen ZP,Wang J
Wed Apr 13 00:00:00 EDT 2022
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Aging
Wang J,Li S,Wang J,Wu F,Chen Y,Zhang H,Guo Y,Lin Y,Li L,Yu X,Liu T,Zhao Y
Mon Jan 06 00:00:00 EST 2020
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis.
Oncogene
Sun Q,Ye Z,Qin Y,Fan G,Ji S,Zhuo Q,Xu W,Liu W,Hu Q,Liu M,Zhang Z,Xu X,Yu X
Thu Oct 01 00:00:00 EDT 2020
miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
Pathology, research and practice
Song Z,Guo Q,Wang H,Gao L,Wang S,Liu D,Liu J,Qi Y,Lin B
Sun Nov 01 00:00:00 EDT 2020
HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells.
PloS one
Auclair M,Guénantin AC,Fellahi S,Garcia M,Capeau J
Mon Apr 06 00:00:00 EDT 2020
Qingjie Fuzheng Granules regulates cancer cell proliferation, apoptosis and tumor angiogenesis in colorectal cancer xenograft mice via Sonic Hedgehog pathway.
Journal of gastrointestinal oncology
Zhu XQ,Yang H,Lin MH,Shang HX,Peng J,Chen WJ,Chen XZ,Lin JM
Tue Dec 01 00:00:00 EST 2020
NCAPG Induces Cell Proliferation in Cardia Adenocarcinoma via PI3K/AKT Signaling Pathway.
OncoTargets and therapy
Zhang X,Wang H,Han Y,Zhu M,Song Z,Zhan D,Jia J
Mon Apr 18 00:00:00 EDT 2022
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Journal of cellular and molecular medicine
Zhang D,Fan R,Lei L,Lei L,Wang Y,Lv N,Chen P,Williamson RA,Wang B,Hu J
Sat Aug 01 00:00:00 EDT 2020
SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression.
Cell death & disease
Cao N,Yu Y,Zhu H,Chen M,Chen P,Zhuo M,Mao Y,Li L,Zhao Q,Wu M,Ye M
Mon May 11 00:00:00 EDT 2020
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Environmental and molecular mutagenesis
Zhao X,Zhang C,Wei X,Shi L,Dai S,Jia J,Wei S,Wang Y,Wang Y,Cheng J,Zhao L
Sat Feb 01 00:00:00 EST 2020
CARLo-5 as an oncogenic gene in endometrial carcinoma.
Environmental and molecular mutagenesis
Zhao X,Zhang C,Wei X,Shi L,Dai S,Jia J,Wei S,Wang Y,Wang Y,Cheng J,Zhao L
Sat Feb 01 00:00:00 EST 2020
SLC25A10 performs an oncogenic role in human osteosarcoma.
Oncology letters
Wang G,Xia J,Chen C,Qiu J,Sun P,Peng Z,Chen X,Xu B
Thu Oct 01 00:00:00 EDT 2020
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
Mechanisms of ageing and development
Wang X,Li D,Wu H,Liu F,Liu F,Zhang Q,Li J
Tue Sep 01 00:00:00 EDT 2020
Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction.
Cell proliferation
Liu L,Wang F,Tong Y,Li LF,Liu Y,Gao WQ
Wed Jan 01 00:00:00 EST 2020
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Journal of cellular physiology
Li F,Zhao F,Li M,Pan M,Shi F,Xu H,Zheng D,Wang L,Dou J
Sun Mar 01 00:00:00 EST 2020
Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.
Bioorganic chemistry
Wu Q,Song Y,Liu R,Wang R,Mei W,Chen W,Yang H,Wang X
Tue Sep 01 00:00:00 EDT 2020
The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer.
International journal of biological sciences
Xu W,Huang M,Guo J,Zhang H,Wang D,Liu T,Liu H,Chen S,Gao P,Mu K
Mon Sep 27 00:00:00 EDT 2021
Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Fundamental & clinical pharmacology
Wang S,Wang H,Sun B,Li D,Wu J,Li J,Tian X,Qin C,Chang H,Liu Y
Sat Feb 01 00:00:00 EST 2020
A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
Journal of cellular and molecular medicine
Jia Y,Jin H,Gao L,Yang X,Wang F,Ding H,Chen A,Tan S,Zhang F,Shao J,Wang S,Zheng S
Fri May 01 00:00:00 EDT 2020
A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
Journal of cellular and molecular medicine
Jia Y,Jin H,Gao L,Yang X,Wang F,Ding H,Chen A,Tan S,Zhang F,Shao J,Wang S,Zheng S
Fri May 01 00:00:00 EDT 2020
Azidothymidine (AZT) Inhibits Proliferation of Human Ovarian Cancer Cells by Regulating Cell Cycle Progression.
Anticancer research
Hsieh Y,Tseng JJ
Thu Oct 01 00:00:00 EDT 2020
COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma.
Cancers
Chu YD,Lin WR,Lin YH,Kuo WH,Tseng CJ,Lim SN,Huang YL,Huang SC,Wu TJ,Lin KH,Yeh CT
Mon Jun 22 00:00:00 EDT 2020
Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma.
OncoTargets and therapy
Lin Z,Qu S,Peng W,Yang P,Zhang R,Zhang P,Guo D,Du J,Wu W,Tao K,Wang J
Tue Apr 12 00:00:00 EDT 2022
CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma.
Cancer biology & medicine
Li T,Wu S,Jia L,Cao W,Yao Y,Zhao G,Li H
Fri May 15 00:00:00 EDT 2020
Downregulation of circular RNA circPVT1 restricts cell growth of hepatocellular carcinoma through downregulation of Sirtuin 7 via microRNA-3666.
Clinical and experimental pharmacology & physiology
Li Y,Shi H,Yuan J,Qiao L,Dong L,Wang Y
Wed Jul 01 00:00:00 EDT 2020
Inhibitor of growth 2 regulates the high glucose-induced cell cycle arrest and epithelial-to-mesenchymal transition in renal proximal tubular cells.
Journal of physiology and biochemistry
Ma Y,Yan R,Wan Q,Lv B,Yang Y,Lv T,Xin W
Sat Aug 01 00:00:00 EDT 2020
Inhibitor of growth 2 regulates the high glucose-induced cell cycle arrest and epithelial-to-mesenchymal transition in renal proximal tubular cells.
Journal of physiology and biochemistry
Ma Y,Yan R,Wan Q,Lv B,Yang Y,Lv T,Xin W
Sat Aug 01 00:00:00 EDT 2020
Inhibitor of growth 2 regulates the high glucose-induced cell cycle arrest and epithelial-to-mesenchymal transition in renal proximal tubular cells.
Journal of physiology and biochemistry
Ma Y,Yan R,Wan Q,Lv B,Yang Y,Lv T,Xin W
Sat Aug 01 00:00:00 EDT 2020
Inhibitor of growth 2 regulates the high glucose-induced cell cycle arrest and epithelial-to-mesenchymal transition in renal proximal tubular cells.
Journal of physiology and biochemistry
Ma Y,Yan R,Wan Q,Lv B,Yang Y,Lv T,Xin W
Sat Aug 01 00:00:00 EDT 2020
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
Frontiers in cell and developmental biology
Jiang X,Li Y,Feng JL,Nik Nabil WN,Wu R,Lu Y,Liu H,Xi ZC,Xu HX
Tue Jan 05 00:00:00 EST 2021
Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Chinese medical journal
Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY
Mon Apr 20 00:00:00 EDT 2020
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
BioMed research international
Zhang J,Zhang H,Shi H,Wang F,Du J,Wang Y,Wei Y,Xue W,Li D,Feng Y,Yan J,Gao Y,Li J,Han J
Mon May 03 00:00:00 EDT 2021
Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.
Applied microbiology and biotechnology
Din SRU,Zhong M,Nisar MA,Saleem MZ,Hussain A,Khinsar KH,Alam S,Ayub G,Kanwal S,Li X,Zhang W,Wang X,Ning A,Cao J,Huang M
Tue Dec 01 00:00:00 EST 2020
mTOR-autophagy promotes pulmonary senescence through IMP1 in chronic toxicity of methamphetamine.
Journal of cellular and molecular medicine
Zhu MJ,Liu BY,Shi L,Wang X,Wang Y
Thu Oct 01 00:00:00 EDT 2020
Minichromosome maintenance protein 5 is an important pathogenic factor of oral squamous cell carcinoma.
Oncology letters
Hao M,Wang H,Zhang C,Li C,Wang X
Thu Oct 01 00:00:00 EDT 2020
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Redox biology
Wang N,Liu H,Liu G,Li M,He X,Yin C,Tu Q,Shen X,Bai W,Wang Q,Tao Y,Yin H
Fri May 01 00:00:00 EDT 2020
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
BMC complementary medicine and therapies
Dai GH,Chen X,Ren ZM,Dai CJ,Tong YL,Chai KQ
Thu Sep 03 00:00:00 EDT 2020
Lactate induced up-regulation of KLHDC8A (Kelch domain-containing 8A) contributes to the proliferation, migration and apoptosis of human glioma cells.
Journal of cellular and molecular medicine
Zhu X,Chen T,Yang H,Lv K
Thu Oct 01 00:00:00 EDT 2020
Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways.
Cancers
Li Y,Chen F,Chen J,Chan S,He Y,Liu W,Zhang G
Mon Jan 06 00:00:00 EST 2020
Predicting direct hepatocyte toxicity in humans by combining high-throughput imaging of HepaRG cells and machine learning-based phenotypic profiling.
Archives of toxicology
Hussain F,Basu S,Heng JJH,Loo LH,Zink D
Sat Aug 01 00:00:00 EDT 2020
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit.
Molecular cancer
Ma C,Wang X,Yang F,Zang Y,Liu J,Wang X,Xu X,Li W,Jia J,Liu Z
Tue Nov 10 00:00:00 EST 2020
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit.
Molecular cancer
Ma C,Wang X,Yang F,Zang Y,Liu J,Wang X,Xu X,Li W,Jia J,Liu Z
Tue Nov 10 00:00:00 EST 2020
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling.
Aging
Xu M,Zhang X,Zhang S,Piao J,Yang Y,Wang X,Lin Z
Thu Dec 03 00:00:00 EST 2020
Identification of osalmid metabolic profile and active metabolites with anti-tumor activity in human hepatocellular carcinoma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu Z,Zhan Y,Wang L,Tong J,Zhang L,Lin M,Jin X,Jiang L,Lou Y,Qiu Y
Thu Oct 01 00:00:00 EDT 2020
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Free radical research
Zhao T,Zhang-Akiyama QM
Tue Sep 01 00:00:00 EDT 2020
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma.
Cancer management and research
Lv Z,Wu K,Qin X,Yuan J,Yan M,Zhang J,Wang L,Ji T,Cao W,Chen W
Fri Apr 15 00:00:00 EDT 2022
Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation.
Biochemical and biophysical research communications
Lin J,Xu R,Shen X,Jiang H,Du S
Thu Oct 15 00:00:00 EDT 2020
Epidermal ROCK2 induces AKT1/GSK3β/β-catenin, NFκB and dermal tenascin C; but enhanced differentiation and p53/p21 inhibit papilloma.
Carcinogenesis
Masre SF,Rath N,Olson MF,Greenhalgh DA
Thu Oct 15 00:00:00 EDT 2020
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Theranostics
Zou G,Zhang X,Wang L,Li X,Xie T,Zhao J,Yan J,Wang L,Ye H,Jiao S,Xiang R,Shi Y
Tue May 18 00:00:00 EDT 2021
Paris polyphylla ethanol extract induces G2/M arrest and suppresses migration and invasion in bladder cancer.
Translational cancer research
Liu Z,Sun Z,Zhang D,Ma C,Jiang Y,Cao G,Sun C,Li K,Xu D,Liu J,Zhao S
Thu Oct 01 00:00:00 EDT 2020
EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression.
Clinical and translational medicine
Zhao H,Wang Y,Yang C,Zhou J,Wang L,Yi K,Li Y,Wang Q,Shi J,Kang C,Zeng L
Tue Jan 28 00:00:00 EST 2020
EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression.
Clinical and translational medicine
Zhao H,Wang Y,Yang C,Zhou J,Wang L,Yi K,Li Y,Wang Q,Shi J,Kang C,Zeng L
Tue Jan 28 00:00:00 EST 2020
A translational program that suppresses metabolism to shield the genome.
Nature communications
Balukoff NC,Ho JJD,Theodoridis PR,Wang M,Bokros M,Llanio LM,Krieger JR,Schatz JH,Lee S
Fri Nov 13 00:00:00 EST 2020
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products.
Cancer cell international
Li K,Zhao S,Long J,Su J,Wu L,Tao J,Zhou J,Zhang J,Chen X,Peng C
Tue Apr 12 00:00:00 EDT 2022
Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p.
Pathology, research and practice
Dao R,Wudu M,Hui L,Jiang J,Xu Y,Ren H,Qiu X
Sun Mar 01 00:00:00 EST 2020
E2F7, regulated by miR‑30c, inhibits apoptosis and promotes cell cycle of prostate cancer cells.
Oncology reports
Wang Y,Pei X,Xu P,Tan Z,Zhu Z,Zhang G,Jiang Z,Deng Z
Tue Sep 01 00:00:00 EDT 2020
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
Neoplasma
Yu ZY,Jiang XY,Zhao RR,Luo CJ,Ren YX,Ma ZJ,Ye HL,Shi WG,Wang C,Jiao ZY
Sun Nov 01 00:00:00 EDT 2020
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells.
Nature communications
Gao X,Wang Q,Wang Y,Liu J,Liu S,Liu J,Zhou X,Zhou L,Chen H,Pan L,Chen J,Wang D,Zhang Q,Shen S,Xiao Y,Wu Z,Cheng Y,Chen G,Kubra S,Qin J,Huang L,Zhang P,Wang C,Moses RE,Lonard DM,Malley BWO,Fares F,Zhang B,Li X,Li L,Xiao J
Thu Aug 06 00:00:00 EDT 2020
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Journal of cellular and molecular medicine
Liu H,Chen C,Ma D,Li Y,Yin Q,Li Q,Xiang C
Mon Jun 01 00:00:00 EDT 2020
Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu M,Ren L,Liang F,Zhang Y,Jiang L,Ma W,Li C,Li X,Ye X
Sun May 17 00:00:00 EDT 2020
LINC00511 contributes to glioblastoma tumorigenesis and epithelial-mesenchymal transition via LINC00511/miR-524-5p/YB1/ZEB1 positive feedback loop.
Journal of cellular and molecular medicine
Du X,Tu Y,Liu S,Zhao P,Bao Z,Li C,Li J,Pan M,Ji J
Wed Jan 01 00:00:00 EST 2020
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
International journal of molecular sciences
Zhao Q,Zhu HP,Xie X,Mao Q,Liu YQ,He XH,Peng C,Jiang QL,Huang W
Sat Mar 07 00:00:00 EST 2020
Identification of apoptosis-associated protein factors distinctly expressed in cigarette smoke condensate-exposed airway bronchial epithelial cells.
Journal of biochemical and molecular toxicology
Lin BC,Li QY,Tian L,Liu HL,Liu XH,Shi Y,He C,Ding SS,Yan J,Li K,Bian LP,Lai WQ,Zhang W,Li X,Xi ZG
Sun Mar 01 00:00:00 EST 2020
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Biochemical and biophysical research communications
Wu J,Lu K,Zhu M,Xie X,Ding Y,Shao X,Chen Y,Liu J,Xu M,Xu Y,Zhou J,Shen X,Zhu C
Wed Jan 22 00:00:00 EST 2020
HDAC5-mediated deacetylation and nuclear localisation of SOX9 is critical for tamoxifen resistance in breast cancer.
British journal of cancer
Xue Y,Lian W,Zhi J,Yang W,Li Q,Guo X,Gao J,Qu H,Lin W,Li Z,Lai L,Wang Q
Sun Dec 01 00:00:00 EST 2019
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma.
Oncogene
Sun B,Zhao X,Ming J,Liu X,Liu D,Jiang C
Thu Aug 01 00:00:00 EDT 2019
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Journal of cellular physiology
Pan JH,Zhou H,Zhu SB,Huang JL,Zhao XX,Ding H,Qin L,Pan YL
Mon Apr 01 00:00:00 EDT 2019
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Journal of cellular physiology
Pan JH,Zhou H,Zhu SB,Huang JL,Zhao XX,Ding H,Qin L,Pan YL
Mon Apr 01 00:00:00 EDT 2019
Effect of ingredients from Chinese herbs on enterovirus D68 production.
Phytotherapy research : PTR
Meng X,Yu X,Liu C,Wang Y,Song F,Huan C,Huo W,Zhang S,Li Z,Zhang J,Zhang W,Yu J
Tue Jan 01 00:00:00 EST 2019
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Pifithrin-α enhancing anticancer effect of topotecan on p53-expressing cancer cells.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Guo J,Tang Q,Wang Q,Sun W,Pu Z,Wang J,Bao Y
Fri Feb 01 00:00:00 EST 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways.
Experimental eye research
Wei X,Luo D,Yan Y,Yu H,Sun L,Wang C,Song F,Ge H,Qian H,Li X,Tang X,Liu P
Fri Mar 01 00:00:00 EST 2019
REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.
Journal of cancer research and clinical oncology
Sun S,Hu Z,Huang S,Ye X,Wang J,Chang J,Wu X,Wang Q,Zhang L,Hu X,Yu H
Sun Sep 01 00:00:00 EDT 2019
Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer.
Medical science monitor : international medical journal of experimental and clinical research
Li Y,Zu X,Hu X,Wang L,He W
Mon Nov 25 00:00:00 EST 2019
p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53.
Cancer science
Zhou Y,Niu W,Luo Y,Li H,Xie Y,Wang H,Liu Y,Fan S,Li Z,Xiong W,Li X,Ren C,Tan M,Li G,Zhou M
Fri Mar 01 00:00:00 EST 2019
p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53.
Cancer science
Zhou Y,Niu W,Luo Y,Li H,Xie Y,Wang H,Liu Y,Fan S,Li Z,Xiong W,Li X,Ren C,Tan M,Li G,Zhou M
Fri Mar 01 00:00:00 EST 2019
Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer.
Frontiers in oncology
Guo S,Jian L,Tao K,Chen C,Yu H,Liu S
Thu Oct 01 00:00:00 EDT 2020
DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53.
Journal of experimental & clinical cancer research : CR
Wudu M,Ren H,Hui L,Jiang J,Zhang S,Xu Y,Wang Q,Su H,Jiang X,Dao R,Qiu X
Tue Feb 12 00:00:00 EST 2019
Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma.
OncoTargets and therapy
Qin H,Li Y,Zhang H,Wang F,He H,Bai X,Li S
Fri Apr 08 00:00:00 EDT 2022
Potent and specific MTH1 inhibitors targeting gastric cancer.
Cell death & disease
Zhou W,Ma L,Yang J,Qiao H,Li L,Guo Q,Ma J,Zhao L,Wang J,Jiang G,Wan X,Adam Goscinski M,Ding L,Zheng Y,Li W,Liu H,Suo Z,Zhao W
Tue Jun 04 00:00:00 EDT 2019
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Cancer management and research
Liu LL,Zhu JM,Yu XN,Zhu HR,Shi X,Bilegsaikhan E,Guo HY,Wu J,Shen XZ
Sun Apr 10 00:00:00 EDT 2022
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Pharmacological research
Guo J,Wang Q,Zhang Y,Sun W,Zhang S,Li Y,Wang J,Bao Y
Sun Sep 01 00:00:00 EDT 2019
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
European journal of medicinal chemistry
Gao F,Liang Y,Zhou P,Cheng J,Ding K,Wang Y
Sun Sep 15 00:00:00 EDT 2019
Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Peng W,Tong C,Li L,Huang C,Ran Y,Chen X,Bai Y,Liu Y,Zhao J,Tan B,Luo X,Wang H,Wen L,Zhang C,Zhang H,Ding Y,Qi H,Baker PN
Wed May 01 00:00:00 EDT 2019
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
Cancer biomarkers : section A of Disease markers
Wang X,Jin Q,Wang X,Chen W,Cai Z
Fri Mar 20 00:00:00 EDT 2020
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Signal transduction and targeted therapy
Li Y,Li X,Cao M,Jiang Y,Yan J,Liu Z,Yang R,Chen X,Sun P,Xiang R,Wang L,Shi Y
Fri Jan 29 00:00:00 EST 2021
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Biochemical pharmacology
Liu Y,Fan D
Tue Oct 01 00:00:00 EDT 2019
Dimethyl fumarate suppresses hepatocellular carcinoma progression via activating SOCS3/JAK1/STAT3 signaling pathway.
American journal of translational research
Liu H,Feng XD,Yang B,Tong RL,Lu YJ,Chen DY,Zhou L,Xie HY,Zheng SS,Wu J
Thu Oct 01 00:00:00 EDT 2020
Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts.
International journal of molecular medicine
Pan C,Lang H,Zhang T,Wang R,Lin X,Shi P,Zhao F,Pang X
Fri Nov 01 00:00:00 EDT 2019
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Bioscience reports
Sun X,Xie Y,Sun X,Yao Y,Li H,Li Z,Yao R,Xu K
Fri Mar 29 00:00:00 EDT 2019
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Journal of enzyme inhibition and medicinal chemistry
Qin F,Wang Y,Jiang X,Wang Y,Zhang N,Wen X,Wang L,Jiang Q,He G
Sun Dec 01 00:00:00 EST 2019
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Cancer research
Wang D,Li W,Zhao R,Chen L,Liu N,Tian Y,Zhao H,Xie M,Lu F,Fang Q,Liang W,Yin F,Li Z
Mon Apr 15 00:00:00 EDT 2019
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
BMC complementary and alternative medicine
Que Z,Zhou Z,Luo B,Dong C,Jiang Y,Li H,Tian J
Wed Aug 07 00:00:00 EDT 2019
Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction.
Experimental & molecular medicine
Zhang L,Li F,Su X,Li Y,Wang Y,Fang R,Guo Y,Jin T,Shan H,Zhao X,Yang R,Shan H,Liang H
Thu Jul 04 00:00:00 EDT 2019
YY1/BCCIP Coordinately Regulates P53-Responsive Element (p53RE)-Mediated Transactivation of p21Waf1/Cip1.
International journal of molecular sciences
Sui Y,Wu T,Li F,Wang F,Cai Y,Jin J
Sun Apr 28 00:00:00 EDT 2019
YY1/BCCIP Coordinately Regulates P53-Responsive Element (p53RE)-Mediated Transactivation of p21Waf1/Cip1.
International journal of molecular sciences
Sui Y,Wu T,Li F,Wang F,Cai Y,Jin J
Sun Apr 28 00:00:00 EDT 2019
Fibronectin regulates the self-renewal of rabbit limbal epithelial stem cells by stimulating the Wnt11/Fzd7/ROCK non-canonical Wnt pathway.
Experimental eye research
Zheng M,Tian C,Fan T,Xu B
Thu Aug 01 00:00:00 EDT 2019
A combination of low-dose decitabine and chidamide resulted in synergistic effects on the proliferation and apoptosis of human myeloid leukemia cell lines.
American journal of translational research
Xu F,Guo H,Shi M,Liu S,Wei M,Sun K,Chen Y
Wed Sep 30 00:00:00 EDT 2020
Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
Aging
Yan Y,Yu H,Sun L,Liu H,Wang C,Wei X,Song F,Li H,Ge H,Qian H,Li X,Tang X,Liu P
Fri May 10 00:00:00 EDT 2019
Self-Assembled saRNA Delivery System Based on Rolling Circle Transcription for Aptamer-Targeting Cancer Therapy.
ACS applied bio materials
Wang T,Hong S,Luo Y,Lv H,Zhang Y,Pei R
Mon Nov 18 00:00:00 EST 2019
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Experimental and therapeutic medicine
Gao X,Zhang Y,Zhang R,Zhao Z,Zhang H,Wu J,Shen W,Zhong M
Tue Oct 01 00:00:00 EDT 2019
Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop.
Journal of experimental & clinical cancer research : CR
Yang B,Wu A,Hu Y,Tao C,Wang JM,Lu Y,Xing R
Mon Jul 01 00:00:00 EDT 2019
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Gastroenterology
Luo Y,Xie C,Brocker CN,Fan J,Wu X,Feng L,Wang Q,Zhao J,Lu D,Tandon M,Cam M,Krausz KW,Liu W,Gonzalez FJ
Sun Sep 01 00:00:00 EDT 2019
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Gastroenterology
Luo Y,Xie C,Brocker CN,Fan J,Wu X,Feng L,Wang Q,Zhao J,Lu D,Tandon M,Cam M,Krausz KW,Liu W,Gonzalez FJ
Sun Sep 01 00:00:00 EDT 2019
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis.
Cancer research and treatment
Li N,Piao J,Wang X,Kim KY,Bae JY,Ren X,Lin Z
Tue Oct 01 00:00:00 EDT 2019
lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
Aging
Lin X,Zhan JK,Zhong JY,Wang YJ,Wang Y,Li S,He JY,Tan P,Chen YY,Liu XB,Cui XJ,Liu YS
Thu Jan 17 00:00:00 EST 2019
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
EBioMedicine
Han Y,Wu P,Wang Z,Zhang Z,Sun S,Liu J,Gong S,Gao P,Iwakuma T,Molina-Vila MA,Chen BP,Zhang Y,Ji T,Mo Q,Chen P,Hu J,Wang S,Zhou J,Lu H,Gao Q
Fri Feb 01 00:00:00 EST 2019
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
EBioMedicine
Han Y,Wu P,Wang Z,Zhang Z,Sun S,Liu J,Gong S,Gao P,Iwakuma T,Molina-Vila MA,Chen BP,Zhang Y,Ji T,Mo Q,Chen P,Hu J,Wang S,Zhou J,Lu H,Gao Q
Fri Feb 01 00:00:00 EST 2019
SIRT1 suppresses p53-dependent apoptosis by modulation of p21 in osteoblast-like MC3T3-E1 cells exposed to fluoride.
Toxicology in vitro : an international journal published in association with BIBRA
Gu X,Wang Z,Gao J,Han D,Zhang L,Chen P,Luo G,Han B
Sat Jun 01 00:00:00 EDT 2019
CircNR3C1 inhibits proliferation of bladder cancer cells by sponging miR-27a-3p and downregulating cyclin D1 expression.
Cancer letters
Zheng F,Wang M,Li Y,Huang C,Tao D,Xie F,Zhang H,Sun J,Zhang C,Gu C,Wang Z,Jiang G
Sat Sep 28 00:00:00 EDT 2019
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
Molecular and cellular biochemistry
Liu R,Xu X,Liang C,Chen X,Yu X,Zhong H,Xu W,Cheng Y,Wang W,Wu Y,Yu L,Hu X
Sat Jun 01 00:00:00 EDT 2019
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.
American journal of translational research
Li F,Su M,Zhao H,Xie W,Cao S,Xu Y,Chen W,Wang L,Hou L,Tan W
Thu Oct 01 00:00:00 EDT 2020
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer.
Artificial cells, nanomedicine, and biotechnology
Sun J,Zhang H,Tao D,Xie F,Liu F,Gu C,Wang M,Wang L,Jiang G,Wang Z,Xiao X
Sun Dec 01 00:00:00 EST 2019
Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner.
International immunopharmacology
He J,Hong B,Bian M,Jin H,Chen J,Shao J,Zhang F,Zheng S
Tue Oct 01 00:00:00 EDT 2019
Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.
OncoTargets and therapy
Hu YH,Ma S,Zhang XN,Zhang ZY,Zhu HF,Ji YH,Li J,Qian XL,Wang YX
Sun Apr 10 00:00:00 EDT 2022
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
International journal of medical sciences
Wang Q,Jia S,Jiao Y,Xu L,Wang D,Chen X,Hu X,Liang H,Wen N,Zhang S,Guo B,Zhang L
Thu Apr 30 00:00:00 EDT 2020
TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
Journal of translational medicine
Bie YN,Gu P,Chen YT,Zhou XX,Tian YG,Yang Q,Li HY,Lin X,Guan YH,Lin TY,Lu X,Shen HF,Fang TX,Liu YM,Xiao D,Gu WW
Thu Mar 07 00:00:00 EST 2019
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats.
Molecular medicine reports
Chen L,He PL,Yang J,Yang YF,Wang K,Amend B,Stenzl A,Zhang YM,Wang ZL,Xing SS,Luo X
Mon Apr 01 00:00:00 EDT 2019
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
PloS one
Liu H,Zhao J,Fu R,Zhu C,Fan D
Fri Jan 24 00:00:00 EST 2020
Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
Life sciences
Lin X,Li S,Wang YJ,Wang Y,Zhong JY,He JY,Cui XJ,Zhan JK,Liu YS
Sun Sep 01 00:00:00 EDT 2019
Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway.
Oncology reports
Yu H,Fu QR,Huang ZJ,Lin JY,Chen QX,Wang Q,Shen DY
Tue Jan 01 00:00:00 EST 2019
Three kinds of corneal host cells contribute differently to corneal neovascularization.
EBioMedicine
Yu H,Sun L,Cui J,Li Y,Yan Y,Wei X,Wang C,Song F,Jiang W,Liu Y,Ge H,Qian H,Li X,Tang X,Liu P
Sat Jun 01 00:00:00 EDT 2019
Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.
Theranostics
Zhao Z,Li L,Du P,Ma L,Zhang W,Zheng L,Lan B,Zhang B,Ma F,Xu B,Zhan Q,Song Y
Fri Jan 31 00:00:00 EST 2020
NF-κB inhibition promotes apoptosis in androgen-independent prostate cancer cells by the photothermal effect via the IκBα/AR signaling pathway.
Biomaterials science
Kong C,Hao M,Chen X,Zhao X,Wang Y,Li J,Gao Y,Zhang H,Yang B,Jiang J
Tue May 28 00:00:00 EDT 2019
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
Journal of cellular physiology
Fang C,He W,Xu T,Dai J,Xu L,Sun F
Wed May 01 00:00:00 EDT 2019
MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma.
Cancer biology & therapy
Fan X,Wang Y,Song J,Wu H,Yang M,Lu L,Weng X,Liu L,Nie G
Fri Aug 21 00:00:00 EDT 2020
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Life science alliance
Tian S,Feng J,Cao Y,Shen S,Cai Y,Yang D,Yan R,Wang L,Zhang H,Zhong X,Gao P
Tue Oct 01 00:00:00 EDT 2019
Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria.
Materials (Basel, Switzerland)
Zhao J,Honda Y,Tanaka T,Hashimoto Y,Matsumoto N
Mon Dec 23 00:00:00 EST 2019
Long Non-coding RNA SNHG12 Functions as a Competing Endogenous RNA to Regulate MDM4 Expression by Sponging miR-129-5p in Clear Cell Renal Cell Carcinoma.
Frontiers in oncology
Wu Z,Chen D,Wang K,Cao C,Xu X
Thu Oct 01 00:00:00 EDT 2020
Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways.
Cancer biology & therapy
Cui D,Zhao Y,Xu J
Mon Jul 06 00:00:00 EDT 2020
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
BMC cancer
Shen Z,Liao X,Shao Z,Feng M,Yuan J,Wang S,Gan S,Ha Y,He Z,Jie W
Fri Mar 22 00:00:00 EDT 2019
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Aging
Wei C,Zhang R,Cai Q,Gao X,Tong F,Dong J,Hu Y,Wu G,Dong X
Sun Sep 08 00:00:00 EDT 2019
Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide.
Cell cycle (Georgetown, Tex.)
Wang SY,Wang WJ,Liu JQ,Song YH,Li P,Sun XF,Cai GY,Chen XM
Mon Jul 01 00:00:00 EDT 2019
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Biochemical and biophysical research communications
Li S,Yao M,Niu C,Liu D,Tang Z,Gu C,Zhao H,Ke J,Wu S,Wang X,Wu F
Tue Sep 03 00:00:00 EDT 2019
ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma.
OncoTargets and therapy
Ye Z,Zeng Z,Shen Y,Yang Q,Chen D,Chen Z,Shen S
Thu Oct 01 00:00:00 EDT 2020
miR-384-5p Targets Gli2 and Negatively Regulates Age-Related Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells.
Stem cells and development
Li X,Wu J,Liu S,Zhang K,Miao X,Li J,Shi Z,Gao Y
Sat Jun 15 00:00:00 EDT 2019
Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
Journal of cellular physiology
Sui A,Xu Y,Pan B,Guo T,Wu J,Shen Y,Yang J,Guo X
Thu Aug 01 00:00:00 EDT 2019
RAD54B potentiates tumor growth and predicts poor prognosis of patients with luminal A breast cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Z,Li X,Han Y,Ji T,Huang X,Gao Q,Ma D
Tue Oct 01 00:00:00 EDT 2019
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Aging cell
Liu A,Guo E,Yang J,Yang Y,Liu S,Jiang X,Hu Q,Dirsch O,Dahmen U,Zhang C,Gewirtz DA,Fang H
Thu Feb 01 00:00:00 EST 2018
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Aging cell
Liu A,Guo E,Yang J,Yang Y,Liu S,Jiang X,Hu Q,Dirsch O,Dahmen U,Zhang C,Gewirtz DA,Fang H
Thu Feb 01 00:00:00 EST 2018
miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase).
Arteriosclerosis, thrombosis, and vascular biology
Badi I,Mancinelli L,Polizzotto A,Ferri D,Zeni F,Burba I,Milano G,Brambilla F,Saccu C,Bianchi ME,Pompilio G,Capogrossi MC,Raucci A
Sat Sep 01 00:00:00 EDT 2018
miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase).
Arteriosclerosis, thrombosis, and vascular biology
Badi I,Mancinelli L,Polizzotto A,Ferri D,Zeni F,Burba I,Milano G,Brambilla F,Saccu C,Bianchi ME,Pompilio G,Capogrossi MC,Raucci A
Sat Sep 01 00:00:00 EDT 2018
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Antioxidants & redox signaling
Ren T,Wang J,Zhang H,Yuan P,Zhu J,Wu Y,Huang Q,Guo X,Zhang J,Ji L,Li J,Zhang H,Yang H,Xing J
Fri Apr 20 00:00:00 EDT 2018
MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation.
Antioxidants & redox signaling
Ren T,Wang J,Zhang H,Yuan P,Zhu J,Wu Y,Huang Q,Guo X,Zhang J,Ji L,Li J,Zhang H,Yang H,Xing J
Fri Apr 20 00:00:00 EDT 2018
Up-regulated MiR-27-3p promotes the G1-S phase transition by targeting inhibitor of growth family member 5 in osteosarcoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ye P,Ke X,Zang X,Sun H,Dong Z,Lin J,Wang L,Liu W,Miao G,Tan Y,Tong W,Xiao H,Gao L
Tue May 01 00:00:00 EDT 2018
Up-regulated MiR-27-3p promotes the G1-S phase transition by targeting inhibitor of growth family member 5 in osteosarcoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ye P,Ke X,Zang X,Sun H,Dong Z,Lin J,Wang L,Liu W,Miao G,Tan Y,Tong W,Xiao H,Gao L
Tue May 01 00:00:00 EDT 2018
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 EDT 2018
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 EDT 2018
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 EDT 2018
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 EDT 2018
mTORC2 facilitates endothelial cell senescence by suppressing Nrf2 expression via the Akt/GSK-3β/C/EBPα signaling pathway.
Acta pharmacologica Sinica
Yang HW,Hong HL,Luo WW,Dai CM,Chen XY,Wang LP,Li Q,Li ZQ,Liu PQ,Li ZM
Sat Dec 01 00:00:00 EST 2018
mTORC2 facilitates endothelial cell senescence by suppressing Nrf2 expression via the Akt/GSK-3β/C/EBPα signaling pathway.
Acta pharmacologica Sinica
Yang HW,Hong HL,Luo WW,Dai CM,Chen XY,Wang LP,Li Q,Li ZQ,Liu PQ,Li ZM
Sat Dec 01 00:00:00 EST 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
International journal of oncology
Jia W,Jiang X,Liu W,Wang L,Zhu B,Zhu H,Liu X,Zhong M,Xie D,Huang W,Jia W,Li S,Liu X,Zuo X,Cheng D,Dai J,Ren C
Fri Jun 01 00:00:00 EDT 2018
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
International journal of oncology
Jia W,Jiang X,Liu W,Wang L,Zhu B,Zhu H,Liu X,Zhong M,Xie D,Huang W,Jia W,Li S,Liu X,Zuo X,Cheng D,Dai J,Ren C
Fri Jun 01 00:00:00 EDT 2018
Hematopoietic Substrate-1-Associated Protein X-1 Regulates the Proliferation and Apoptosis of Endothelial Progenitor Cells Through Akt Pathway Modulation.
Stem cells (Dayton, Ohio)
Guo XB,Deng X,Wei Y
Thu Mar 01 00:00:00 EST 2018
Hematopoietic Substrate-1-Associated Protein X-1 Regulates the Proliferation and Apoptosis of Endothelial Progenitor Cells Through Akt Pathway Modulation.
Stem cells (Dayton, Ohio)
Guo XB,Deng X,Wei Y
Thu Mar 01 00:00:00 EST 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.
Journal of proteome research
Yang F,Yi M,Liu Y,Wang Q,Hu Y,Deng H
Fri Mar 02 00:00:00 EST 2018
Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.
Journal of proteome research
Yang F,Yi M,Liu Y,Wang Q,Hu Y,Deng H
Fri Mar 02 00:00:00 EST 2018
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Molecular pharmaceutics
Chen X,Liu C,Zhao R,Zhao P,Wu J,Zhou N,Ying M
Mon Nov 05 00:00:00 EST 2018
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
Molecular pharmaceutics
Chen X,Liu C,Zhao R,Zhao P,Wu J,Zhou N,Ying M
Mon Nov 05 00:00:00 EST 2018
Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis.
OncoTargets and therapy
Liu X,Zhao Y,Zhang W,Gao Y,Huo M,Liu M,Xiao Z,Liang S,Xu N,Zhu H
Thu Mar 17 00:00:00 EDT 2022
Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis.
OncoTargets and therapy
Liu X,Zhao Y,Zhang W,Gao Y,Huo M,Liu M,Xiao Z,Liang S,Xu N,Zhu H
Thu Mar 17 00:00:00 EDT 2022
Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis.
OncoTargets and therapy
Liu X,Zhao Y,Zhang W,Gao Y,Huo M,Liu M,Xiao Z,Liang S,Xu N,Zhu H
Thu Mar 17 00:00:00 EDT 2022
Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis.
OncoTargets and therapy
Liu X,Zhao Y,Zhang W,Gao Y,Huo M,Liu M,Xiao Z,Liang S,Xu N,Zhu H
Thu Mar 17 00:00:00 EDT 2022
Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo.
OncoTargets and therapy
Ling Z,Guan H,You Z,Wang C,Hu L,Zhang L,Wang Y,Chen S,Xu B,Chen M
Sun Apr 10 00:00:00 EDT 2022
Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo.
OncoTargets and therapy
Ling Z,Guan H,You Z,Wang C,Hu L,Zhang L,Wang Y,Chen S,Xu B,Chen M
Sun Apr 10 00:00:00 EDT 2022
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Toxicology letters
Wang J,Chen J,Jiang Y,Shi Y,Zhu J,Xie C,Geng S,Wu J,Zhang Q,Wang X,Meng Y,Li Y,Chen Y,Cao W,Wang X,Zhong C,Li X
Sun Jul 01 00:00:00 EDT 2018
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Toxicology letters
Wang J,Chen J,Jiang Y,Shi Y,Zhu J,Xie C,Geng S,Wu J,Zhang Q,Wang X,Meng Y,Li Y,Chen Y,Cao W,Wang X,Zhong C,Li X
Sun Jul 01 00:00:00 EDT 2018
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Experimental gerontology
Wang W,Cai G,Chen X
Sun Jul 01 00:00:00 EDT 2018
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Experimental gerontology
Wang W,Cai G,Chen X
Sun Jul 01 00:00:00 EDT 2018
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Archives of biochemistry and biophysics
Wen W,Chen J,Ding L,Luo X,Zheng X,Dai Q,Gu Q,Liu C,Liang M,Guo X,Liu P,Li M
Thu Nov 01 00:00:00 EDT 2018
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Archives of biochemistry and biophysics
Wen W,Chen J,Ding L,Luo X,Zheng X,Dai Q,Gu Q,Liu C,Liang M,Guo X,Liu P,Li M
Thu Nov 01 00:00:00 EDT 2018
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Cell and tissue research
Zhang T,Wang P,Liu Y,Zhou J,Shi Z,Cheng K,Huang T,Wang X,Yang GL,Yang B,Ma S,Guan F
Wed Aug 01 00:00:00 EDT 2018
Overexpression of FOXQ1 enhances anti-senescence and migration effects of human umbilical cord mesenchymal stem cells in vitro and in vivo.
Cell and tissue research
Zhang T,Wang P,Liu Y,Zhou J,Shi Z,Cheng K,Huang T,Wang X,Yang GL,Yang B,Ma S,Guan F
Wed Aug 01 00:00:00 EDT 2018
Anticancer effect of histone deacetylase inhibitor scriptaid as a single agent for hepatocellular carcinoma.
Bioscience reports
Liu L,Sun X,Xie Y,Zhuang Y,Yao R,Xu K
Fri Aug 31 00:00:00 EDT 2018
Anticancer effect of histone deacetylase inhibitor scriptaid as a single agent for hepatocellular carcinoma.
Bioscience reports
Liu L,Sun X,Xie Y,Zhuang Y,Yao R,Xu K
Fri Aug 31 00:00:00 EDT 2018
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
FEBS letters
Yu M,Wang H,Liu J,Qin H,Liu S,Yan Q
Thu Nov 01 00:00:00 EDT 2018
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.
FEBS letters
Yu M,Wang H,Liu J,Qin H,Liu S,Yan Q
Thu Nov 01 00:00:00 EDT 2018
Comparative characterization of SHED and DPSCs during extended cultivation in vitro.
Molecular medicine reports
Wang H,Zhong Q,Yang T,Qi Y,Fu M,Yang X,Qiao L,Ling Q,Liu S,Zhao Y
Tue May 01 00:00:00 EDT 2018
Comparative characterization of SHED and DPSCs during extended cultivation in vitro.
Molecular medicine reports
Wang H,Zhong Q,Yang T,Qi Y,Fu M,Yang X,Qiao L,Ling Q,Liu S,Zhao Y
Tue May 01 00:00:00 EDT 2018
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Bao Y,Zhang S,Guo Y,Wei X,Zhang Y,Yang Y,Zhang H,Ma M,Yang W
Sat Sep 01 00:00:00 EDT 2018
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Bao Y,Zhang S,Guo Y,Wei X,Zhang Y,Yang Y,Zhang H,Ma M,Yang W
Sat Sep 01 00:00:00 EDT 2018
Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A.
Biochemical and biophysical research communications
Xue X,Wang X,Zhao Y,Hu R,Qin L
Sat Aug 25 00:00:00 EDT 2018
Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A.
Biochemical and biophysical research communications
Xue X,Wang X,Zhao Y,Hu R,Qin L
Sat Aug 25 00:00:00 EDT 2018
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
Biochemical and biophysical research communications
Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R
Sun Dec 09 00:00:00 EST 2018
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
Biochemical and biophysical research communications
Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R
Sun Dec 09 00:00:00 EST 2018
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
Biochemical and biophysical research communications
Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R
Sun Dec 09 00:00:00 EST 2018
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
Biochemical and biophysical research communications
Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R
Sun Dec 09 00:00:00 EST 2018
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Oncology letters
Huang B,Lv DJ,Wang C,Shu FP,Gong ZC,Xie T,Yu YZ,Song XL,Xie JJ,Li S,Liu YM,Qi H,Zhao SC
Wed Aug 01 00:00:00 EDT 2018
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Oncology letters
Huang B,Lv DJ,Wang C,Shu FP,Gong ZC,Xie T,Yu YZ,Song XL,Xie JJ,Li S,Liu YM,Qi H,Zhao SC
Wed Aug 01 00:00:00 EDT 2018
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Frontiers in cellular and infection microbiology
Wang Z,Wang Y,Wang S,Meng X,Song F,Huo W,Zhang S,Chang J,Li J,Zheng B,Liu Y,Zhang Y,Zhang W,Yu J
Fri Aug 16 00:00:00 EDT 2019
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production.
Frontiers in cellular and infection microbiology
Wang Z,Wang Y,Wang S,Meng X,Song F,Huo W,Zhang S,Chang J,Li J,Zheng B,Liu Y,Zhang Y,Zhang W,Yu J
Fri Aug 16 00:00:00 EDT 2019
S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells.
Molecules (Basel, Switzerland)
Fan Y,Mao Y,Cao S,Xia G,Zhang Q,Zhang H,Qiu F,Kang N
Sat Dec 01 00:00:00 EST 2018
S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells.
Molecules (Basel, Switzerland)
Fan Y,Mao Y,Cao S,Xia G,Zhang Q,Zhang H,Qiu F,Kang N
Sat Dec 01 00:00:00 EST 2018
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Cell death & disease
Shen H,Zhan M,Zhang Y,Huang S,Xu S,Huang X,He M,Yao Y,Man M,Wang J
Mon Jan 22 00:00:00 EST 2018
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Cell death & disease
Shen H,Zhan M,Zhang Y,Huang S,Xu S,Huang X,He M,Yao Y,Man M,Wang J
Mon Jan 22 00:00:00 EST 2018
A pH probe inhibits senescence in mesenchymal stem cells.
Stem cell research & therapy
Wang L,Han X,Qu G,Su L,Zhao B,Miao J
Fri Dec 07 00:00:00 EST 2018
A pH probe inhibits senescence in mesenchymal stem cells.
Stem cell research & therapy
Wang L,Han X,Qu G,Su L,Zhao B,Miao J
Fri Dec 07 00:00:00 EST 2018
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
Oncotarget
Zhang J,Yuan JP,Wang Q,Shao LH,Liu SP,Firestone RA,Hong YP,Li JG,Xin YC,Li Y
Fri Jan 05 00:00:00 EST 2018
Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer.
Oncotarget
Zhang J,Yuan JP,Wang Q,Shao LH,Liu SP,Firestone RA,Hong YP,Li JG,Xin YC,Li Y
Fri Jan 05 00:00:00 EST 2018
Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.
Journal of the Endocrine Society
Uesato T,Ogihara T,Hara A,Iida H,Miyatsuka T,Fujitani Y,Takeda S,Watada H
Thu Mar 01 00:00:00 EST 2018
Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.
Journal of the Endocrine Society
Uesato T,Ogihara T,Hara A,Iida H,Miyatsuka T,Fujitani Y,Takeda S,Watada H
Thu Mar 01 00:00:00 EST 2018
SNHG6 Promotes Tumor Growth via Repression of P21 in Colorectal Cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li Z,Qiu R,Qiu X,Tian T
Tue Sep 18 00:00:00 EDT 2018
SNHG6 Promotes Tumor Growth via Repression of P21 in Colorectal Cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li Z,Qiu R,Qiu X,Tian T
Tue Sep 18 00:00:00 EDT 2018
Anti-Proliferative Activity of HPOB against Multiple Myeloma Cells via p21 Transcriptional Activation.
Molecules (Basel, Switzerland)
Liu L,Sun X,Xie Y,Zhuang Y,Yao R,Xu K
Mon Apr 30 00:00:00 EDT 2018
The chromatin remodeling protein INO80 contributes to the removal of H2A.Z at the p53-binding site of the p21 gene in response to doxorubicin.
The FEBS journal
Ding J,Yu C,Sui Y,Wang L,Yang Y,Wang F,Yao H,Xing F,Liu H,Li Y,Shah JA,Cai Y,Jin J
Sat Sep 01 00:00:00 EDT 2018
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Cancers
Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH
Mon Dec 31 00:00:00 EST 2018
Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways.
Cancers
Chen YA,Tzeng DTW,Huang YP,Lin CJ,Lo UG,Wu CL,Lin H,Hsieh JT,Tang CH,Lai CH
Mon Dec 31 00:00:00 EST 2018
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy.
Scientific reports
Napoli E,Song G,Panoutsopoulos A,Riyadh MA,Kaushik G,Halmai J,Levenson R,Zarbalis KS,Giulivi C
Fri Jul 27 00:00:00 EDT 2018
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy.
Scientific reports
Napoli E,Song G,Panoutsopoulos A,Riyadh MA,Kaushik G,Halmai J,Levenson R,Zarbalis KS,Giulivi C
Fri Jul 27 00:00:00 EDT 2018
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.
Aging
Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
Tue Jul 24 00:00:00 EDT 2018
NF-κB/miR-223-3p/ARID1A axis is involved in Helicobacter pylori CagA-induced gastric carcinogenesis and progression.
Cell death & disease
Yang F,Xu Y,Liu C,Ma C,Zou S,Xu X,Jia J,Liu Z
Tue Jan 09 00:00:00 EST 2018
NF-κB/miR-223-3p/ARID1A axis is involved in Helicobacter pylori CagA-induced gastric carcinogenesis and progression.
Cell death & disease
Yang F,Xu Y,Liu C,Ma C,Zou S,Xu X,Jia J,Liu Z
Tue Jan 09 00:00:00 EST 2018
IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53.
The Journal of biological chemistry
Jiang B,Zhao W,Shi M,Zhang J,Chen A,Ma H,Suleman M,Lin F,Zhou L,Wang J,Zhang Y,Liu M,Wen S,Ouyang C,Wang H,Huang X,Zhou H,Li Q
Fri Jun 22 00:00:00 EDT 2018
IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53.
The Journal of biological chemistry
Jiang B,Zhao W,Shi M,Zhang J,Chen A,Ma H,Suleman M,Lin F,Zhou L,Wang J,Zhang Y,Liu M,Wen S,Ouyang C,Wang H,Huang X,Zhou H,Li Q
Fri Jun 22 00:00:00 EDT 2018
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
Molecular cancer
Xie F,Li Y,Wang M,Huang C,Tao D,Zheng F,Zhang H,Zeng F,Xiao X,Jiang G
Wed Oct 03 00:00:00 EDT 2018
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.
Molecular cancer
Xie F,Li Y,Wang M,Huang C,Tao D,Zheng F,Zhang H,Zeng F,Xiao X,Jiang G
Wed Oct 03 00:00:00 EDT 2018
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Journal of translational medicine
Zhang ZF,Zhang HR,Zhang QY,Lai SY,Feng YZ,Zhou Y,Zheng SR,Shi R,Zhou JY
Fri Jan 19 00:00:00 EST 2018
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Journal of translational medicine
Zhang ZF,Zhang HR,Zhang QY,Lai SY,Feng YZ,Zhou Y,Zheng SR,Shi R,Zhou JY
Fri Jan 19 00:00:00 EST 2018
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
International journal of molecular sciences
Zhang W,Yao F,Zhang H,Li N,Zou X,Sui L,Hou L
Tue Jan 02 00:00:00 EST 2018
The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica.
International journal of molecular sciences
Zhang W,Yao F,Zhang H,Li N,Zou X,Sui L,Hou L
Tue Jan 02 00:00:00 EST 2018
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
Cancer medicine
Chen SM,Lin TK,Tseng YY,Tu CH,Lui TN,Huang SF,Hsieh LL,Li YY
Wed Aug 01 00:00:00 EDT 2018
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
Cancer medicine
Chen SM,Lin TK,Tseng YY,Tu CH,Lui TN,Huang SF,Hsieh LL,Li YY
Wed Aug 01 00:00:00 EDT 2018
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
British journal of pharmacology
Liu T,Zhang Z,Yu C,Zeng C,Xu X,Wu G,Huang Z,Li W
Fri Dec 01 00:00:00 EST 2017
Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.
British journal of pharmacology
Liu T,Zhang Z,Yu C,Zeng C,Xu X,Wu G,Huang Z,Li W
Fri Dec 01 00:00:00 EST 2017
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
EMBO reports
Shen Y,Liu S,Fan J,Jin Y,Tian B,Zheng X,Fu H
Sat Apr 01 00:00:00 EDT 2017
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
EMBO reports
Shen Y,Liu S,Fan J,Jin Y,Tian B,Zheng X,Fu H
Sat Apr 01 00:00:00 EDT 2017
Downregulation of B-myb promotes senescence via the ROS-mediated p53/p21 pathway, in vascular endothelial cells.
Cell proliferation
Zhou Z,Yin Y,Chang Q,Sun G,Lin J,Dai Y
Sat Apr 01 00:00:00 EDT 2017
miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence.
American journal of respiratory cell and molecular biology
Cui H,Ge J,Xie N,Banerjee S,Zhou Y,Antony VB,Thannickal VJ,Liu G
Wed Feb 01 00:00:00 EST 2017
miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence.
American journal of respiratory cell and molecular biology
Cui H,Ge J,Xie N,Banerjee S,Zhou Y,Antony VB,Thannickal VJ,Liu G
Wed Feb 01 00:00:00 EST 2017
H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing.
Oxidative medicine and cellular longevity
Wu W,Hou CL,Mu XP,Sun C,Zhu YC,Wang MJ,Lv QZ
Fri Mar 02 00:00:00 EST 2018
H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing.
Oxidative medicine and cellular longevity
Wu W,Hou CL,Mu XP,Sun C,Zhu YC,Wang MJ,Lv QZ
Fri Mar 02 00:00:00 EST 2018
miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.
American journal of physiology. Lung cellular and molecular physiology
Cui H,Ge J,Xie N,Banerjee S,Zhou Y,Liu RM,Thannickal VJ,Liu G
Wed Mar 01 00:00:00 EST 2017
miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.
American journal of physiology. Lung cellular and molecular physiology
Cui H,Ge J,Xie N,Banerjee S,Zhou Y,Liu RM,Thannickal VJ,Liu G
Wed Mar 01 00:00:00 EST 2017
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
The international journal of biochemistry & cell biology
Yin Y,Zhou Z,Liu W,Chang Q,Sun G,Dai Y
Wed Mar 01 00:00:00 EST 2017
Nurr1 promotes intestinal regeneration after ischemia/reperfusion injury by inhibiting the expression of p21 (Waf1/Cip1).
Journal of molecular medicine (Berlin, Germany)
Zu G,Yao J,Ji A,Ning S,Luo F,Li Z,Feng D,Rui Y,Li Y,Wang G,Tian X
Sun Jan 01 00:00:00 EST 2017
Nurr1 promotes intestinal regeneration after ischemia/reperfusion injury by inhibiting the expression of p21 (Waf1/Cip1).
Journal of molecular medicine (Berlin, Germany)
Zu G,Yao J,Ji A,Ning S,Luo F,Li Z,Feng D,Rui Y,Li Y,Wang G,Tian X
Sun Jan 01 00:00:00 EST 2017
ISG15 inhibits cancer cell growth and promotes apoptosis.
International journal of molecular medicine
Zhou MJ,Chen FZ,Chen HC,Wan XX,Zhou X,Fang Q,Zhang DZ
Wed Feb 01 00:00:00 EST 2017
ISG15 inhibits cancer cell growth and promotes apoptosis.
International journal of molecular medicine
Zhou MJ,Chen FZ,Chen HC,Wan XX,Zhou X,Fang Q,Zhang DZ
Wed Feb 01 00:00:00 EST 2017
TRPC5 channel modulates endothelial cells senescence.
European journal of pharmacology
Li Z,Guo G,Wang H,Si X,Zhou G,Xiong Y,Li S,Dai R,Yang C
Fri May 05 00:00:00 EDT 2017
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y
Wed Nov 15 00:00:00 EST 2017
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y
Wed Nov 15 00:00:00 EST 2017
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
Journal of vascular surgery
Lu HY,Huang CY,Shih CM,Lin YW,Tsai CS,Lin FY,Shih CC
Sun Oct 01 00:00:00 EDT 2017
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
Journal of vascular surgery
Lu HY,Huang CY,Shih CM,Lin YW,Tsai CS,Lin FY,Shih CC
Sun Oct 01 00:00:00 EDT 2017
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
American journal of translational research
Yao R,Han D,Sun X,Fu C,Wu Q,Yao Y,Li H,Li Z,Xu K
Thu Oct 01 00:00:00 EDT 2020
Histone deacetylase inhibitor NaBut suppresses cell proliferation and induces apoptosis by targeting p21 in multiple myeloma.
American journal of translational research
Yao R,Han D,Sun X,Fu C,Wu Q,Yao Y,Li H,Li Z,Xu K
Thu Oct 01 00:00:00 EDT 2020
Co‑expression of murine double minute 2 siRNA and wild‑type p53 induces G1 cell cycle arrest in H1299 cells.
Molecular medicine reports
Liu L,Zhang P,Guo H,Tang X,Liu L,Li J,Guo R,Cai Y,Liu Y,Li Y
Fri Dec 01 00:00:00 EST 2017
Co‑expression of murine double minute 2 siRNA and wild‑type p53 induces G1 cell cycle arrest in H1299 cells.
Molecular medicine reports
Liu L,Zhang P,Guo H,Tang X,Liu L,Li J,Guo R,Cai Y,Liu Y,Li Y
Fri Dec 01 00:00:00 EST 2017
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Biochemical and biophysical research communications
Lei K,Liang X,Gao Y,Xu B,Xu Y,Li Y,Tao Y,Shi W,Liu J
Sat Mar 11 00:00:00 EST 2017
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Biochemical and biophysical research communications
Lei K,Liang X,Gao Y,Xu B,Xu Y,Li Y,Tao Y,Shi W,Liu J
Sat Mar 11 00:00:00 EST 2017
Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
Anti-cancer drugs
Chong D,Ma L,Liu F,Zhang Z,Zhao S,Huo Q,Zhang P,Zheng H,Liu H
Fri Sep 01 00:00:00 EDT 2017
Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
Anti-cancer drugs
Chong D,Ma L,Liu F,Zhang Z,Zhao S,Huo Q,Zhang P,Zheng H,Liu H
Fri Sep 01 00:00:00 EDT 2017
Inhibited effects of CAPE-pNO2 on cervical carcinoma in vivo and in vitro and its detected metabolites.
Oncotarget
Yao X,Tang H,Ren Q,Zhao X,Zuo H,Li Z
Tue Nov 07 00:00:00 EST 2017
Inhibited effects of CAPE-pNO2 on cervical carcinoma in vivo and in vitro and its detected metabolites.
Oncotarget
Yao X,Tang H,Ren Q,Zhao X,Zuo H,Li Z
Tue Nov 07 00:00:00 EST 2017
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Scientific reports
Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y
Thu Oct 19 00:00:00 EDT 2017
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Scientific reports
Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y
Thu Oct 19 00:00:00 EDT 2017
Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa.
Oncotarget
Ma H,Li L,Dou G,Wang C,Li J,He H,Wu M,Qi H
Tue Apr 25 00:00:00 EDT 2017
Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa.
Oncotarget
Ma H,Li L,Dou G,Wang C,Li J,He H,Wu M,Qi H
Tue Apr 25 00:00:00 EDT 2017
Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma.
Oncotarget
Liu L,Liu Y,Chen X,Wang M,Zhou Y,Zhou P,Li W,Zhu F
Tue Jul 04 00:00:00 EDT 2017
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Cell & bioscience
Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C
Fri Mar 11 00:00:00 EST 2022
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Cell & bioscience
Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C
Fri Mar 11 00:00:00 EST 2022
T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients.
Journal of the International AIDS Society
Bolduan S,Koppensteiner H,Businger R,Rebensburg S,Kunze C,Brack-Werner R,Draenert R,Schindler M
Tue Sep 19 00:00:00 EDT 2017
T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients.
Journal of the International AIDS Society
Bolduan S,Koppensteiner H,Businger R,Rebensburg S,Kunze C,Brack-Werner R,Draenert R,Schindler M
Tue Sep 19 00:00:00 EDT 2017
USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein.
Oncotarget
Ma Y,Fu HL,Wang Z,Huang H,Ni J,Song J,Xia Y,Jin WL,Cui DX
Tue May 16 00:00:00 EDT 2017
USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein.
Oncotarget
Ma Y,Fu HL,Wang Z,Huang H,Ni J,Song J,Xia Y,Jin WL,Cui DX
Tue May 16 00:00:00 EDT 2017
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Scientific reports
Tang H,Yao X,Yao C,Zhao X,Zuo H,Li Z
Tue Aug 08 00:00:00 EDT 2017
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Scientific reports
Tang H,Yao X,Yao C,Zhao X,Zuo H,Li Z
Tue Aug 08 00:00:00 EDT 2017
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
Scientific reports
Lin G,Zhu S,Wu Y,Song C,Wang W,Zhang Y,Chen YL,He Z
Wed Jun 07 00:00:00 EDT 2017
ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines.
Scientific reports
Lin G,Zhu S,Wu Y,Song C,Wang W,Zhang Y,Chen YL,He Z
Wed Jun 07 00:00:00 EDT 2017
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Oncotarget
Zhao W,Lu D,Liu L,Cai J,Zhou Y,Yang Y,Zhang Y,Zhang J
Tue Nov 07 00:00:00 EST 2017
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
Oncotarget
Zhao W,Lu D,Liu L,Cai J,Zhou Y,Yang Y,Zhang Y,Zhang J
Tue Nov 07 00:00:00 EST 2017
Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.
Journal of experimental & clinical cancer research : CR
Zhang J,Wen X,Liu N,Li YQ,Tang XR,Wang YQ,He QM,Yang XJ,Zhang PP,Ma J,Sun Y
Thu Oct 19 00:00:00 EDT 2017
Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.
Journal of experimental & clinical cancer research : CR
Zhang J,Wen X,Liu N,Li YQ,Tang XR,Wang YQ,He QM,Yang XJ,Zhang PP,Ma J,Sun Y
Thu Oct 19 00:00:00 EDT 2017
IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.
Molecular medicine reports
Ma Y,Jiang J,Zhang Y,Ding Y,Xu T,Lu B
Tue Aug 01 00:00:00 EDT 2017
Long non-coding RNA UCA1 promotes gallbladder cancer progression by epigenetically repressing p21 and E-cadherin expression.
Oncotarget
Cai Q,Jin L,Wang S,Zhou D,Wang J,Tang Z,Quan Z
Tue Jul 18 00:00:00 EDT 2017
Long non-coding RNA UCA1 promotes gallbladder cancer progression by epigenetically repressing p21 and E-cadherin expression.
Oncotarget
Cai Q,Jin L,Wang S,Zhou D,Wang J,Tang Z,Quan Z
Tue Jul 18 00:00:00 EDT 2017
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Oncotarget
Li X,Jiang Z,Feng J,Zhang X,Wu J,Chen W
Fri Sep 22 00:00:00 EDT 2017
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Oncotarget
Li X,Jiang Z,Feng J,Zhang X,Wu J,Chen W
Fri Sep 22 00:00:00 EDT 2017
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
Scientific reports
Qi Y,Li X,Chang C,Xu F,He Q,Zhao Y,Wu L
Wed May 24 00:00:00 EDT 2017
Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome.
Scientific reports
Qi Y,Li X,Chang C,Xu F,He Q,Zhao Y,Wu L
Wed May 24 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Oncotarget
Hu YH,Chen Q,Lu YX,Zhang JM,Lin C,Zhang F,Zhang WJ,Li XM,Zhang W,Li XN
Tue Jul 11 00:00:00 EDT 2017
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Oncotarget
Hu YH,Chen Q,Lu YX,Zhang JM,Lin C,Zhang F,Zhang WJ,Li XM,Zhang W,Li XN
Tue Jul 11 00:00:00 EDT 2017
miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling.
Antioxidants & redox signaling
Wang G,Yao J,Li Z,Zu G,Feng D,Shan W,Li Y,Hu Y,Zhao Y,Tian X
Fri Jun 10 00:00:00 EDT 2016
miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling.
Antioxidants & redox signaling
Wang G,Yao J,Li Z,Zu G,Feng D,Shan W,Li Y,Hu Y,Zhao Y,Tian X
Fri Jun 10 00:00:00 EDT 2016
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y
Thu Dec 15 00:00:00 EST 2016
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y
Thu Dec 15 00:00:00 EST 2016
MiR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells.
International journal of oncology
Chu K,Gao G,Yang X,Ren S,Li Y,Wu H,Huang Y,Zhou C
Mon Feb 01 00:00:00 EST 2016
MiR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells.
International journal of oncology
Chu K,Gao G,Yang X,Ren S,Li Y,Wu H,Huang Y,Zhou C
Mon Feb 01 00:00:00 EST 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
P21(Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng S,Tang S,Dai C,Zhou Y,Yang X,Li D,Xiao X
Mon Feb 01 00:00:00 EST 2016
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Cell cycle (Georgetown, Tex.)
Yuan S,Wen J,Cheng J,Shen W,Zhou S,Yan W,Shen L,Luo A,Wang S
Tue Nov 01 00:00:00 EDT 2016
HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma.
Oncology reports
Wang Z,Tang F,Hu P,Wang Y,Gong J,Sun S,Xie C
Fri Jul 01 00:00:00 EDT 2016
HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma.
Oncology reports
Wang Z,Tang F,Hu P,Wang Y,Gong J,Sun S,Xie C
Fri Jul 01 00:00:00 EDT 2016
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
American journal of translational research
Chen ZH,Hu HK,Zhang CR,Lu CY,Bao Y,Cai Z,Zou YX,Hu GH,Jiang L
Thu May 18 00:00:00 EDT 2023
Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
American journal of translational research
Chen ZH,Hu HK,Zhang CR,Lu CY,Bao Y,Cai Z,Zou YX,Hu GH,Jiang L
Thu May 18 00:00:00 EDT 2023
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
Cancer chemotherapy and pharmacology
Zhen N,Yang Q,Wu Q,Zhu X,Wang Y,Sun F,Mei W,Yu Y
Fri Jan 01 00:00:00 EST 2016
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
Cancer chemotherapy and pharmacology
Zhen N,Yang Q,Wu Q,Zhu X,Wang Y,Sun F,Mei W,Yu Y
Fri Jan 01 00:00:00 EST 2016
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Oncology letters
Xu Y,Wu D,Fan Y,Li P,Du H,Shi J,Wang D,Zhou X
Sat Oct 01 00:00:00 EDT 2016
Macrophage migration inhibitory factor in the regulation of myoblast proliferation and differentiation.
Bioscience, biotechnology, and biochemistry
Wen F,Zheng J,Yu J,Gao M,Gao S,Zhou Y,Liu J,Yang Z
Fri Jul 01 00:00:00 EDT 2016
Macrophage migration inhibitory factor in the regulation of myoblast proliferation and differentiation.
Bioscience, biotechnology, and biochemistry
Wen F,Zheng J,Yu J,Gao M,Gao S,Zhou Y,Liu J,Yang Z
Fri Jul 01 00:00:00 EDT 2016
Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21Waf1/Cip1 and p27Kip1.
Taiwanese journal of obstetrics & gynecology
Zhou Y,Wang K,Zhen S,Wang R,Luo W
Thu Dec 01 00:00:00 EST 2016
Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21Waf1/Cip1 and p27Kip1.
Taiwanese journal of obstetrics & gynecology
Zhou Y,Wang K,Zhen S,Wang R,Luo W
Thu Dec 01 00:00:00 EST 2016
Effects of resveratrol on ARPE-19 cell proliferation and migration via regulating the expression of proliferating cell nuclear antigen, P21, P27 and p38MAPK/MMP-9.
International journal of ophthalmology
Hao XN,Wang WJ,Chen J,Zhou Q,Qu YX,Liu XY,Xu W
Thu Oct 01 00:00:00 EDT 2020
Effects of resveratrol on ARPE-19 cell proliferation and migration via regulating the expression of proliferating cell nuclear antigen, P21, P27 and p38MAPK/MMP-9.
International journal of ophthalmology
Hao XN,Wang WJ,Chen J,Zhou Q,Qu YX,Liu XY,Xu W
Thu Oct 01 00:00:00 EDT 2020
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Oncotarget
Chen P,Yu N,Zhang Z,Zhang P,Yang Y,Wu N,Xu L,Zhang J,Ge J,Yu K,Zhuang J
Tue Feb 02 00:00:00 EST 2016
Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.
Oncotarget
Chen P,Yu N,Zhang Z,Zhang P,Yang Y,Wu N,Xu L,Zhang J,Ge J,Yu K,Zhuang J
Tue Feb 02 00:00:00 EST 2016
Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation.
Scientific reports
Xu X,Pang J,Chen Y,Bucala R,Zhang Y,Ren J
Fri Mar 04 00:00:00 EST 2016
miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation.
Oncotarget
Feng T,Shao F,Wu Q,Zhang X,Xu D,Qian K,Xie Y,Wang S,Xu N,Wang Y,Qi C
Tue Mar 29 00:00:00 EDT 2016
miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation.
Oncotarget
Feng T,Shao F,Wu Q,Zhang X,Xu D,Qian K,Xie Y,Wang S,Xu N,Wang Y,Qi C
Tue Mar 29 00:00:00 EDT 2016
Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.
Journal of clinical biochemistry and nutrition
Fei Z,Gao Y,Qiu M,Qi X,Dai Y,Wang S,Quan Z,Liu Y,Ou J
Tue Mar 01 00:00:00 EST 2016
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Scientific reports
Dia VP,Krishnan HB
Thu Sep 15 00:00:00 EDT 2016
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Scientific reports
Dia VP,Krishnan HB
Thu Sep 15 00:00:00 EDT 2016
Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.
The Journal of biological chemistry
Liao Y,Chu HP,Hu Z,Merkin JJ,Chen J,Liu Z,Degenhardt K,White E,Ryazanov AG
Fri Sep 09 00:00:00 EDT 2016
Simvastatin exerts anti-hepatitis B virus activity by inhibiting expression of minichromosome maintenance protein 7 in HepG2.2.15 cells.
Molecular medicine reports
Li W,Cao F,Li J,Wang Z,Ren Y,Liang Z,Liu P
Thu Dec 01 00:00:00 EST 2016
A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells.
The Journal of biological chemistry
Xia L,Wang XR,Wang XL,Liu SH,Ding XW,Chen GQ,Lu Y
Fri Dec 09 00:00:00 EST 2016
A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells.
The Journal of biological chemistry
Xia L,Wang XR,Wang XL,Liu SH,Ding XW,Chen GQ,Lu Y
Fri Dec 09 00:00:00 EST 2016
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
Leukemia research
Fan SJ,Li HB,Cui G,Kong XL,Sun LL,Zhao YQ,Li YH,Zhou J
Mon Feb 01 00:00:00 EST 2016
Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.
Oncotarget
Dai Y,Wang L,Tang J,Cao P,Luo Z,Sun J,Kiflu A,Sai B,Zhang M,Wang F,Li G,Xiang J
Tue May 03 00:00:00 EDT 2016
Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.
Oncotarget
Dai Y,Wang L,Tang J,Cao P,Luo Z,Sun J,Kiflu A,Sai B,Zhang M,Wang F,Li G,Xiang J
Tue May 03 00:00:00 EDT 2016
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Nutrients
Wang Y,Zhang XN,Xie WH,Zheng YX,Cao JP,Cao PR,Chen QJ,Li X,Sun CD
Tue Sep 27 00:00:00 EDT 2016
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Nutrients
Wang Y,Zhang XN,Xie WH,Zheng YX,Cao JP,Cao PR,Chen QJ,Li X,Sun CD
Tue Sep 27 00:00:00 EDT 2016
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Nutrients
Wang Y,Zhang XN,Xie WH,Zheng YX,Cao JP,Cao PR,Chen QJ,Li X,Sun CD
Tue Sep 27 00:00:00 EDT 2016
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Nutrients
Wang Y,Zhang XN,Xie WH,Zheng YX,Cao JP,Cao PR,Chen QJ,Li X,Sun CD
Tue Sep 27 00:00:00 EDT 2016
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Oncotarget
Zhan L,Cao H,Wang G,Lyu Y,Sun X,An J,Wu Z,Huang Q,Liu B,Xing J
Tue Oct 04 00:00:00 EDT 2016
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma.
Oncotarget
Zhan L,Cao H,Wang G,Lyu Y,Sun X,An J,Wu Z,Huang Q,Liu B,Xing J
Tue Oct 04 00:00:00 EDT 2016
Hydrogen sulfide mediates the protection of dietary restriction against renal senescence in aged F344 rats.
Scientific reports
Wang WJ,Cai GY,Ning YC,Cui J,Hong Q,Bai XY,Xu XM,Bu R,Sun XF,Chen XM
Tue Jul 26 00:00:00 EDT 2016
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Oncotarget
Chen S,Sun KX,Liu BL,Zong ZH,Zhao Y
Tue May 10 00:00:00 EDT 2016
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Oncotarget
Chen S,Sun KX,Liu BL,Zong ZH,Zhao Y
Tue May 10 00:00:00 EDT 2016
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Scientific reports
Ye J,Yao Y,Song Q,Li S,Hu Z,Yu Y,Hu C,Da X,Li H,Chen Q,Wang QK
Tue Oct 04 00:00:00 EDT 2016
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Scientific reports
Ye J,Yao Y,Song Q,Li S,Hu Z,Yu Y,Hu C,Da X,Li H,Chen Q,Wang QK
Tue Oct 04 00:00:00 EDT 2016
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Scientific reports
Ye J,Yao Y,Song Q,Li S,Hu Z,Yu Y,Hu C,Da X,Li H,Chen Q,Wang QK
Tue Oct 04 00:00:00 EDT 2016
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Scientific reports
Ye J,Yao Y,Song Q,Li S,Hu Z,Yu Y,Hu C,Da X,Li H,Chen Q,Wang QK
Tue Oct 04 00:00:00 EDT 2016
Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions.
Scientific reports
Fischer A,Warscheid B,Weber W,Radziwill G
Wed Nov 30 00:00:00 EST 2016
Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions.
Scientific reports
Fischer A,Warscheid B,Weber W,Radziwill G
Wed Nov 30 00:00:00 EST 2016
Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects.
Developmental cell
Zalc A,Rattenbach R,Auradé F,Cadot B,Relaix F
Mon Apr 06 00:00:00 EDT 2015
Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects.
Developmental cell
Zalc A,Rattenbach R,Auradé F,Cadot B,Relaix F
Mon Apr 06 00:00:00 EDT 2015
Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Aging cell
Hua Y,Robinson TJ,Cao Y,Shi GP,Ren J,Nair S
Mon Jun 01 00:00:00 EDT 2015
Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Aging cell
Hua Y,Robinson TJ,Cao Y,Shi GP,Ren J,Nair S
Mon Jun 01 00:00:00 EDT 2015
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Oncology research
Zhou C,Zhang P,Xu GC,Wu DM,Liu RY,Zeng Q,Wang CT
Mon Feb 06 00:00:00 EST 2017
RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Oncology research
Zhou C,Zhang P,Xu GC,Wu DM,Liu RY,Zeng Q,Wang CT
Mon Feb 06 00:00:00 EST 2017
RTEF-1 protects against oxidative damage induced by H2O2 in human umbilical vein endothelial cells through Klotho activation.
Experimental biology and medicine (Maywood, N.J.)
Sun S,Cheng B,Sun PG,Wu XH,Wu QQ,He P
Tue Dec 01 00:00:00 EST 2015
RTEF-1 protects against oxidative damage induced by H2O2 in human umbilical vein endothelial cells through Klotho activation.
Experimental biology and medicine (Maywood, N.J.)
Sun S,Cheng B,Sun PG,Wu XH,Wu QQ,He P
Tue Dec 01 00:00:00 EST 2015
Down-Regulated NRSN2 Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma.
Digestive diseases and sciences
Wang X,Han L,Zhang J,Xia Q
Thu Oct 01 00:00:00 EDT 2015
Down-Regulated NRSN2 Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma.
Digestive diseases and sciences
Wang X,Han L,Zhang J,Xia Q
Thu Oct 01 00:00:00 EDT 2015
Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy.
Biochemical and biophysical research communications
Zhu L,Dong C,Sun C,Ma R,Yang D,Zhu H,Xu J
Fri Aug 21 00:00:00 EDT 2015
Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy.
Biochemical and biophysical research communications
Zhu L,Dong C,Sun C,Ma R,Yang D,Zhu H,Xu J
Fri Aug 21 00:00:00 EDT 2015
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
Asian Pacific journal of cancer prevention : APJCP
Wu DM,Zhang P,Xu GC,Tong AP,Zhou C,Lang JY,Wang CT
Tue Dec 08 00:00:00 EST 2015
Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.
Asian Pacific journal of cancer prevention : APJCP
Wu DM,Zhang P,Xu GC,Tong AP,Zhou C,Lang JY,Wang CT
Tue Dec 08 00:00:00 EST 2015
FXR induces SOCS3 and suppresses hepatocellular carcinoma.
Oncotarget
Guo F,Xu Z,Zhang Y,Jiang P,Huang G,Chen S,Lyu X,Zheng P,Zhao X,Zeng Y,Wang S,He F
Tue Oct 27 00:00:00 EDT 2015
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Stem cells international
Geng S,Mu XY,Chen XB,Hou JY,Jia DY,Xu CY,Wang YP
Wed Jun 24 00:00:00 EDT 2015
MKL1 inhibits cell cycle progression through p21 in podocytes.
BMC molecular biology
Yang S,Liu L,Xu P,Yang Z
Thu Feb 12 00:00:00 EST 2015
MKL1 inhibits cell cycle progression through p21 in podocytes.
BMC molecular biology
Yang S,Liu L,Xu P,Yang Z
Thu Feb 12 00:00:00 EST 2015
Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.
PloS one
Cao L,Ding J,Dong L,Zhao J,Su J,Wang L,Sui Y,Zhao T,Wang F,Jin J,Cai Y
Tue May 17 00:00:00 EDT 2016
Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.
PloS one
Cao L,Ding J,Dong L,Zhao J,Su J,Wang L,Sui Y,Zhao T,Wang F,Jin J,Cai Y
Tue May 17 00:00:00 EDT 2016
Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II.
The Journal of biological chemistry
Liu M,Chen Y,Zhang L,Wang Q,Ma X,Li X,Xiang R,Zhu Y,Qin S,Yu Y,Jiang XC,Duan Y,Han J
Fri Jun 05 00:00:00 EDT 2015
Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II.
The Journal of biological chemistry
Liu M,Chen Y,Zhang L,Wang Q,Ma X,Li X,Xiang R,Zhu Y,Qin S,Yu Y,Jiang XC,Duan Y,Han J
Fri Jun 05 00:00:00 EDT 2015
Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways.
Asian Pacific journal of cancer prevention : APJCP
Luo N,Zhao LC,Shi QQ,Feng ZQ,Chen DL,Li J
Tue Jan 26 00:00:00 EST 2016
Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways.
Asian Pacific journal of cancer prevention : APJCP
Luo N,Zhao LC,Shi QQ,Feng ZQ,Chen DL,Li J
Tue Jan 26 00:00:00 EST 2016
Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.
Oncotarget
Liu T,Men Q,Wu G,Yu C,Huang Z,Liu X,Li W
Fri Apr 10 00:00:00 EDT 2015
Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.
Oncotarget
Liu T,Men Q,Wu G,Yu C,Huang Z,Liu X,Li W
Fri Apr 10 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
PloS one
Ying Q,Ansong E,Diamond AM,Lu Z,Yang W,Bie X
Thu Feb 04 00:00:00 EST 2016
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
PloS one
Ying Q,Ansong E,Diamond AM,Lu Z,Yang W,Bie X
Thu Feb 04 00:00:00 EST 2016
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
The Journal of biological chemistry
Li H,Liu Q,Wang Z,Fang R,Shen Y,Cai X,Gao Y,Li Y,Zhang X,Ye L
Fri Sep 11 00:00:00 EDT 2015
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
The Journal of biological chemistry
Li H,Liu Q,Wang Z,Fang R,Shen Y,Cai X,Gao Y,Li Y,Zhang X,Ye L
Fri Sep 11 00:00:00 EDT 2015
MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3.
Oncotarget
Fan Z,Cui H,Xu X,Lin Z,Zhang X,Kang L,Han B,Meng J,Yan Z,Yan X,Jiao S
Tue Sep 22 00:00:00 EDT 2015
MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3.
Oncotarget
Fan Z,Cui H,Xu X,Lin Z,Zhang X,Kang L,Han B,Meng J,Yan Z,Yan X,Jiao S
Tue Sep 22 00:00:00 EDT 2015
Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway.
Cancer letters
Yang CF,Peng LX,Huang TJ,Yang GD,Chu QQ,Liang YY,Cao X,Xie P,Zheng LS,Huang HB,Cai MD,Huang JL,Liu RY,Zhu ZY,Qian CN,Huang BJ
Fri Mar 28 00:00:00 EDT 2014
Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway.
Cancer letters
Yang CF,Peng LX,Huang TJ,Yang GD,Chu QQ,Liang YY,Cao X,Xie P,Zheng LS,Huang HB,Cai MD,Huang JL,Liu RY,Zhu ZY,Qian CN,Huang BJ
Fri Mar 28 00:00:00 EDT 2014
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
International journal of oncology
Ning Z,Wang A,Liang J,Xie Y,Liu J,Feng L,Yan Q,Wang Z
Wed Oct 01 00:00:00 EDT 2014
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma.
International journal of oncology
Ning Z,Wang A,Liang J,Xie Y,Liu J,Feng L,Yan Q,Wang Z
Wed Oct 01 00:00:00 EDT 2014
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Metallomics : integrated biometal science
Wu Q,He J,Mei W,Zhang Z,Wu X,Sun F
Mon Dec 01 00:00:00 EST 2014
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Metallomics : integrated biometal science
Wu Q,He J,Mei W,Zhang Z,Wu X,Sun F
Mon Dec 01 00:00:00 EST 2014
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Oncology reports
Sun Q,Wang R,Wang Y,Luo J,Wang P,Cheng B
Sat Feb 01 00:00:00 EST 2014
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Oncology reports
Sun Q,Wang R,Wang Y,Luo J,Wang P,Cheng B
Sat Feb 01 00:00:00 EST 2014
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
The Journal of surgical research
Liu Z,Yang L,Teng X,Zhang H,Guan H
Wed Oct 01 00:00:00 EDT 2014
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
The Journal of surgical research
Liu Z,Yang L,Teng X,Zhang H,Guan H
Wed Oct 01 00:00:00 EDT 2014
Parathyroid hormone-related protein serves as a prognostic indicator in oral squamous cell carcinoma.
Journal of experimental & clinical cancer research : CR
Lv Z,Wu X,Cao W,Shen Z,Wang L,Xie F,Zhang J,Ji T,Yan M,Chen W
Thu Dec 18 00:00:00 EST 2014
Parathyroid hormone-related protein serves as a prognostic indicator in oral squamous cell carcinoma.
Journal of experimental & clinical cancer research : CR
Lv Z,Wu X,Cao W,Shen Z,Wang L,Xie F,Zhang J,Ji T,Yan M,Chen W
Thu Dec 18 00:00:00 EST 2014
miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ.
Molecular cancer
Jung HM,Phillips BL,Chan EK
Tue Apr 08 00:00:00 EDT 2014
miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ.
Molecular cancer
Jung HM,Phillips BL,Chan EK
Tue Apr 08 00:00:00 EDT 2014
Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
PloS one
Storbeck M,Hupperich K,Gaspar JA,Meganathan K,Martínez Carrera L,Wirth R,Sachinidis A,Wirth B
Sat Jan 10 00:00:00 EST 2015
Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
PloS one
Storbeck M,Hupperich K,Gaspar JA,Meganathan K,Martínez Carrera L,Wirth R,Sachinidis A,Wirth B
Sat Jan 10 00:00:00 EST 2015
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Deficiency of insulin-like growth factor 1 attenuates aging-induced changes in hepatic function: role of autophagy.
Journal of hepatology
Xu X,Hueckstaedt LK,Ren J
Thu Aug 01 00:00:00 EDT 2013
Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop.
Oncogene
Zhang J,Sun Q,Zhang Z,Ge S,Han ZG,Chen WT
Thu Jan 03 00:00:00 EST 2013
Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop.
Oncogene
Zhang J,Sun Q,Zhang Z,Ge S,Han ZG,Chen WT
Thu Jan 03 00:00:00 EST 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 EDT 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 EDT 2013
Cell growth inhibition in HPV 18 positive uveal melanoma cells by E6/E7 siRNA.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Cun B,Song X,Jia R,Wang H,Zhao X,Liu B,Ge S,Fan X
Sat Jun 01 00:00:00 EDT 2013
Cell growth inhibition in HPV 18 positive uveal melanoma cells by E6/E7 siRNA.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Cun B,Song X,Jia R,Wang H,Zhao X,Liu B,Ge S,Fan X
Sat Jun 01 00:00:00 EDT 2013
Enhanced therapeutic efficacy of vitamin K2 by silencing BCL-2 expression in SMMC-7721 hepatocellular carcinoma cells.
Oncology letters
Yao Y,Li L,Zhang H,Jia R,Liu B,Zhao X,Zhang L,Qian G,Fan X,Ge S
Sun Jul 01 00:00:00 EDT 2012
Enhanced therapeutic efficacy of vitamin K2 by silencing BCL-2 expression in SMMC-7721 hepatocellular carcinoma cells.
Oncology letters
Yao Y,Li L,Zhang H,Jia R,Liu B,Zhao X,Zhang L,Qian G,Fan X,Ge S
Sun Jul 01 00:00:00 EDT 2012
Hepatitis E virus-induced neurological symptoms in a kidney-transplant patient with chronic hepatitis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Kamar N,Izopet J,Cintas P,Garrouste C,Uro-Coste E,Cointault O,Rostaing L
Sat May 01 00:00:00 EDT 2010
