Product References
Extracellular Calcium-Induced Calcium Transient Regulating the Proliferation of Osteoblasts through Glycolysis Metabolism Pathways.
International journal of molecular sciences
Gao X,Di X,Li J,Kang Y,Xie W,Sun L,Zhang J
Sun Mar 05 00:00:00 EST 2023
Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity.
bioRxiv : the preprint server for biology
Yang D,Wang Y,Qi T,Zhang X,Shen L,Ma J,Pang Z,Lal NK,McClatchy DB,Wang K,Xie Y,Polli F,Maximov A,Augustine V,Cline HT,Yates JR,Ye L
Tue Mar 14 00:00:00 EDT 2023
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
International journal of biological sciences
Zhong C,Long Z,Yang T,Wang S,Zhong W,Hu F,Teoh JY,Lu J,Mao X
Tue Apr 18 00:00:00 EDT 2023
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Frontiers in oncology
Zhu X,Chen H,Li H,Ren H,Ye C,Xu K,Liu J,Du F,Zhang Z,Liu Y,Xie X,Wang M,Ma T,Chong W,Shang L,Li L
Tue Apr 04 00:00:00 EDT 2023
Artificial intelligence reveals dysregulation of osteosarcoma and cuproptosis-related biomarkers, PDHA1, CDKN2A and neutrophils.
Scientific reports
Jiang J,Zhan X,Wei J,Fan Q,Li H,Li H,Li S,Zhao Y,Yin G,Tang L,Wu Y,Lan M,Qin Y,Guo Q,Xu W,Lu L,Yang Y,Zhang Y,Qu H
Sun Mar 26 00:00:00 EDT 2023
Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation.
Cell reports
Mocholi E,Russo L,Gopal K,Ramstead AG,Hochrein SM,Vos HR,Geeven G,Adegoke AO,Hoekstra A,van Es RM,Pittol JR,Vastert S,Rutter J,Radstake T,van Loosdregt J,Berkers C,Mokry M,Anderson CC,O'Connell RM,Vaeth M,Ussher J,Burgering BMT,Coffer PJ
Tue Jun 27 00:00:00 EDT 2023
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang X,Gao L,Deng R,Peng Y,Wu S,Lu J,Liu X
Tue Aug 01 00:00:00 EDT 2023
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang X,Gao L,Deng R,Peng Y,Wu S,Lu J,Liu X
Tue Aug 01 00:00:00 EDT 2023
AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre-eclampsia.
Cell proliferation
Xu P,Zheng Y,Liao J,Hu M,Yang Y,Zhang B,Kilby MD,Fu H,Liu Y,Zhang F,Xiong L,Liu X,Jin H,Wu Y,Huang J,Han T,Wen L,Gao R,Fu Y,Fan X,Qi H,Baker PN,Tong C
Wed Feb 01 00:00:00 EST 2023
Changes in the Expression of MIF and Other Key Enzymes of Energy Metabolism in the Myocardia of Broiler Chickens with Ascites Syndrome.
Animals : an open access journal from MDPI
Li L,Jia Q,Chen L,Wang W
Tue Sep 20 00:00:00 EDT 2022
A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.
Cell stem cell
Du J,Zheng L,Gao P,Yang H,Yang WJ,Guo F,Liang R,Feng M,Wang Z,Zhang Z,Bai L,Bu Y,Xing S,Zheng W,Wang X,Quan L,Hu X,Wu H,Chen Z,Chen L,Wei K,Zhang Z,Zhu X,Zhang X,Tu Q,Zhao SM,Lei X,Xiong JW
Thu Apr 07 00:00:00 EDT 2022
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Frontiers in cardiovascular medicine
Wang M,Zhao M,Yu J,Xu Y,Zhang J,Liu J,Zheng Z,Ye J,Wang Z,Ye D,Feng Y,Xu S,Pan W,Wei C,Wan J
Sat Jul 16 00:00:00 EDT 2022
Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism.
PloS one
Kumstel S,Schreiber T,Goldstein L,Stenzel J,Lindner T,Joksch M,Zhang X,Wendt EHU,Schönrogge M,Krause B,Vollmar B,Zechner D
Tue Apr 26 00:00:00 EDT 2022
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Journal of immunology (Baltimore, Md. : 1950)
Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN
Tue Nov 01 00:00:00 EDT 2022
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism.
Nature communications
Bussi C,Heunis T,Pellegrino E,Bernard EM,Bah N,Dos Santos MS,Santucci P,Aylan B,Rodgers A,Fearns A,Mitschke J,Moore C,MacRae JI,Greco M,Reinheckel T,Trost M,Gutierrez MG
Mon Nov 28 00:00:00 EST 2022
Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Cui YR,Qu F,Zhong WJ,Yang HH,Zeng J,Huang JH,Liu J,Zhang MY,Zhou Y,Guan CX
Wed Jun 01 00:00:00 EDT 2022
Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Cui YR,Qu F,Zhong WJ,Yang HH,Zeng J,Huang JH,Liu J,Zhang MY,Zhou Y,Guan CX
Wed Jun 01 00:00:00 EDT 2022
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
eLife
Fu J,Zhou M,Gritsenko MA,Nakayasu ES,Song L,Luo ZQ
Thu Jan 27 00:00:00 EST 2022
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited.
Nature metabolism
Li Z,Ji BW,Dixit PD,Tchourine K,Lien EC,Hosios AM,Abbott KL,Rutter JC,Westermark AM,Gorodetsky EF,Sullivan LB,Vander Heiden MG,Vitkup D
Wed Jun 01 00:00:00 EDT 2022
Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelial-mesenchymal transition in drug-resistant lung cancer.
Pharmacological research
Wang Q,Wu M,Li H,Rao X,Ao L,Wang H,Yao L,Wang X,Hong X,Wang J,Aa J,Sun M,Wang G,Liu J,Zhou F
Tue Nov 01 00:00:00 EDT 2022
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Song C,Nie C,Sun Y,Wang Y,Xue L,Fan M,Qian H,Wang L,Li Y
Sat Jan 01 00:00:00 EST 2022
Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans.
Clinical and translational medicine
Christen L,Broghammer H,Rapöhn I,Möhlis K,Strehlau C,Ribas-Latre A,Gebhardt C,Roth L,Krause K,Landgraf K,Körner A,Rohde-Zimmermann K,Hoffmann A,Klöting N,Ghosh A,Sun W,Dong H,Wolfrum C,Rassaf T,Hendgen-Cotta UB,Stumvoll M,Blüher M,Heiker JT,Weiner J
Thu Dec 01 00:00:00 EST 2022
Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells.
ACS chemical neuroscience
Yao X,Zhang J,Lu Y,Deng Y,Zhao R,Xiao S
Wed Feb 16 00:00:00 EST 2022
Helichrysetin inhibits gastric cancer growth by targeting c-Myc/PDHK1 axis-mediated energy metabolism reprogramming.
Acta pharmacologica Sinica
Wang P,Jin JM,Liang XH,Yu MZ,Yang C,Huang F,Wu H,Zhang BB,Fei XY,Wang ZT,Xu R,Shi HL,Wu XJ
Wed Jun 01 00:00:00 EDT 2022
Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation.
Frontiers in immunology
Lin HC,Chen YJ,Wei YH,Lin HA,Chen CC,Liu TF,Hsieh YL,Huang KY,Lin KH,Wang HH,Chen LC
Mon Sep 20 00:00:00 EDT 2021
Resveratrol Is a Natural Inhibitor of Human Intestinal Mast Cell Activation and Phosphorylation of Mitochondrial ERK1/2 and STAT3.
International journal of molecular sciences
Bilotta S,Paruchuru LB,Feilhauer K,Köninger J,Lorentz A
Fri Jul 16 00:00:00 EDT 2021
Localization of myoglobin in mitochondria: implication in regulation of mitochondrial respiration in rat skeletal muscle.
Physiological reports
Koma R,Shibaguchi T,Pérez López C,Oka T,Jue T,Takakura H,Masuda K
Mon Mar 01 00:00:00 EST 2021
HIF-1 regulates energy metabolism of the Tibetan chicken brain during embryo development under hypoxia.
American journal of physiology. Regulatory, integrative and comparative physiology
Tang Q,Xu Q,Ding C,Zhang H,Ling Y,Wu C,Fang M
Sat May 01 00:00:00 EDT 2021
Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.
Theranostics
Liu J,Nie C,Xue L,Yan Y,Liu S,Sun J,Fan M,Qian H,Ying H,Wang L,Li Y
Wed Jan 19 00:00:00 EST 2022
Spexin protects cardiomyocytes from hypoxia-induced metabolic and mitochondrial dysfunction.
Naunyn-Schmiedeberg's archives of pharmacology
Liu Y,Sun L,Zheng L,Su M,Liu H,Wei Y,Li D,Wang Y,Dai C,Gong Y,Zhao C,Li Y
Wed Jan 01 00:00:00 EST 2020
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer.
Nature communications
Kodama M,Oshikawa K,Shimizu H,Yoshioka S,Takahashi M,Izumi Y,Bamba T,Tateishi C,Tomonaga T,Matsumoto M,Nakayama KI
Tue Mar 17 00:00:00 EDT 2020
Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
K¿učková K,Thakker A,Vettore L,Escribano-Gonzalez C,Hindshaw RL,Tearle JLE,Goncalves J,Kaul B,Lavery GG,Favier J,Tennant DA
Wed Jan 01 00:00:00 EST 2020
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
American journal of translational research
Chen L,Peng J,Wang Y,Jiang H,Wang W,Dai J,Tang M,Wei Y,Kuang H,Xu G,Xu H,Zhou F
Mon Sep 28 00:00:00 EDT 2020
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice.
Journal of diabetes research
Zhang XM,Deng H,Tong JD,Wang YZ,Ning XC,Yang XH,Zhou FQ,Jin HM
Mon Aug 23 00:00:00 EDT 2021
The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.
Cancer & metabolism
Zhuang Y,Ly RC,Frazier CV,Yu J,Qin S,Fan XY,Goetz MP,Boughey JC,Weinshilboum R,Wang L
Thu Mar 31 00:00:00 EDT 2022
The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.
Cancer & metabolism
Zhuang Y,Ly RC,Frazier CV,Yu J,Qin S,Fan XY,Goetz MP,Boughey JC,Weinshilboum R,Wang L
Thu Mar 31 00:00:00 EDT 2022
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Environment international
Shen X,Chen Y,Zhang J,Yan X,Liu W,Guo Y,Shan Q,Liu S
Mon Jul 01 00:00:00 EDT 2019
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Molecular therapy oncolytics
Zhao H,Wu S,Li H,Duan Q,Zhang Z,Shen Q,Wang C,Yin T
Fri Sep 27 00:00:00 EDT 2019
(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis.
Circulation research
Ren L,Sun Y,Lu H,Ye D,Han L,Wang N,Daugherty A,Li F,Wang M,Su F,Tao W,Sun J,Zelcer N,Mullick AE,Danser AHJ,Jiang Y,He Y,Ruan X,Lu X
Fri Mar 02 00:00:00 EST 2018
(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis.
Circulation research
Ren L,Sun Y,Lu H,Ye D,Han L,Wang N,Daugherty A,Li F,Wang M,Su F,Tao W,Sun J,Zelcer N,Mullick AE,Danser AHJ,Jiang Y,He Y,Ruan X,Lu X
Fri Mar 02 00:00:00 EST 2018
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 EDT 2018
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 EDT 2018
Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer.
Cancer biology & therapy
Ma W,Zhao X,Wang K,Liu J,Huang G
Wed Sep 11 00:00:00 EDT 2019
Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer.
Cancer biology & therapy
Ma W,Zhao X,Wang K,Liu J,Huang G
Wed Sep 11 00:00:00 EDT 2019
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis.
Nature cell biology
Yang Z,Wang Y,Zhang Y,He X,Zhong CQ,Ni H,Chen X,Liang Y,Wu J,Zhao S,Zhou D,Han J
Thu Feb 01 00:00:00 EST 2018
Utilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.
Proteomes
Horita H,Law A,Middleton K
Tue May 22 00:00:00 EDT 2018
Utilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.
Proteomes
Horita H,Law A,Middleton K
Tue May 22 00:00:00 EDT 2018
The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis.
Oncogene
Li G,Li M,Hu J,Lei R,Xiong H,Ji H,Yin H,Wei Q,Hu G
Thu Feb 16 00:00:00 EST 2017
The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis.
Oncogene
Li G,Li M,Hu J,Lei R,Xiong H,Ji H,Yin H,Wei Q,Hu G
Thu Feb 16 00:00:00 EST 2017
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Cell metabolism
Davidson SM,Papagiannakopoulos T,Olenchock BA,Heyman JE,Keibler MA,Luengo A,Bauer MR,Jha AK,O'Brien JP,Pierce KA,Gui DY,Sullivan LB,Wasylenko TM,Subbaraj L,Chin CR,Stephanopolous G,Mott BT,Jacks T,Clish CB,Vander Heiden MG
Tue Mar 08 00:00:00 EST 2016
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Cell metabolism
Davidson SM,Papagiannakopoulos T,Olenchock BA,Heyman JE,Keibler MA,Luengo A,Bauer MR,Jha AK,O'Brien JP,Pierce KA,Gui DY,Sullivan LB,Wasylenko TM,Subbaraj L,Chin CR,Stephanopolous G,Mott BT,Jacks T,Clish CB,Vander Heiden MG
Tue Mar 08 00:00:00 EST 2016
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Biochemical and biophysical research communications
Dong K,Ni H,Wu M,Tang Z,Halim M,Shi D
Fri Aug 05 00:00:00 EDT 2016
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Biochemical and biophysical research communications
Dong K,Ni H,Wu M,Tang Z,Halim M,Shi D
Fri Aug 05 00:00:00 EDT 2016
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Scientific reports
Li P,Zhang D,Shen L,Dong K,Wu M,Ou Z,Shi D
Wed Mar 09 00:00:00 EST 2016
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Scientific reports
Li P,Zhang D,Shen L,Dong K,Wu M,Ou Z,Shi D
Wed Mar 09 00:00:00 EST 2016
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Molecular cell
Zhang J,Fan J,Venneti S,Cross JR,Takagi T,Bhinder B,Djaballah H,Kanai M,Cheng EH,Judkins AR,Pawel B,Baggs J,Cherry S,Rabinowitz JD,Thompson CB
Thu Oct 23 00:00:00 EDT 2014
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Molecular cell
Zhang J,Fan J,Venneti S,Cross JR,Takagi T,Bhinder B,Djaballah H,Kanai M,Cheng EH,Judkins AR,Pawel B,Baggs J,Cherry S,Rabinowitz JD,Thompson CB
Thu Oct 23 00:00:00 EDT 2014
Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.
Neuroscience
Du J,Ma M,Zhao Q,Fang L,Chang J,Wang Y,Fei R,Song X
Tue Feb 12 00:00:00 EST 2013
Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.
Neuroscience
Du J,Ma M,Zhao Q,Fang L,Chang J,Wang Y,Fei R,Song X
Tue Feb 12 00:00:00 EST 2013
