Product References
α-Asarone alleviates allergic asthma by stabilizing mast cells through inhibition of ERK/JAK2-STAT3 pathway.
BioFactors (Oxford, England)
Bai H,Xue Z,Zhang W,Feng C,Zhou Z,Hu S,Zhang Y,Qin Q,Wu Y,Sun X,Zhou Y,Wang N
Sun Jan 01 00:00:00 EST 2023
Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Rα-JAK2-STAT3 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ding Y,Wang Y,Zhang Y,Dang B,Hu S,Zhao C,Huang Y,Zheng G,Ma T,Zhang T
Tue Jul 25 00:00:00 EDT 2023
Involvement of METTL3 in arsenite-induced skin lesions by targeting the SOCS3/STAT3/Krt signaling pathway.
Environmental pollution (Barking, Essex : 1987)
Yang F,Zhang A
Sun Jan 01 00:00:00 EST 2023
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Neural regeneration research
Yu Y,Xia LK,Di Y,Nie QZ,Chen XL
Mon May 01 00:00:00 EDT 2023
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling.
Breast cancer research : BCR
Liu H,Yan R,Xiao Z,Huang X,Yao J,Liu J,An G,Ge Y
Mon Apr 17 00:00:00 EDT 2023
Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis.
European journal of medicinal chemistry
Wang J,Gao T,Ma Y,Zhang Y,Yi Y,Yan F,Cheng Z,Yu Y,Li J,Chen Z,Ding W,Ma Z
Wed Mar 15 00:00:00 EDT 2023
Splicing factor SF3B3, a NS5-binding protein, restricts ZIKV infection by targeting GCH1.
Virologica Sinica
Chen T,Yang H,Liu P,Hamiti M,Zhang X,Xu Y,Quan W,Zhang Y,Yu W,Jiao L,Du T,Xi J,Yin B,Zhou W,Lu S,Peng X
Sat Apr 01 00:00:00 EDT 2023
Discovery of the GSH responsive "Y-PROTACs" targeting ALK and CDK4/6 as a potential treatment for cancer.
European journal of medicinal chemistry
Wang S,Luo D,Pu C,Ma X,Zhang H,Feng Z,Deng R,Yu S,Liu Y,Huang Q,Li R
Wed Feb 15 00:00:00 EST 2023
LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma.
BMC cancer
Chen Y,Ma F,Zhang Z,Guo Y,Shen H,Chen H
Thu May 18 00:00:00 EDT 2023
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
Food & function
Yang Q,He Y,Tian L,Zhang Z,Qiu L,Tao X,Wei H
Tue Feb 21 00:00:00 EST 2023
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Frontiers in pharmacology
Gao Y,Zhang Z,Du J,Yang X,Wang X,Wen K,Sun X
Tue May 09 00:00:00 EDT 2023
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Archives of medical research
Al-Raimi HAI,Kong J,Ran Y,Zhu L,Li J,Liu X,Yang X,Qi D,Liu T
Sun Jan 01 00:00:00 EST 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Frontiers in pharmacology
Li J,Wu B,Zeng L,Lin Y,Chen Q,Wang H,An L,Zhang J,Chen S,Huang J,Zhan R,Zhang G
Mon Jul 03 00:00:00 EDT 2023
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Digestive diseases and sciences
Yang J,Han F,Wu G,Dong Y,Su H,Xu J,Li J
Wed Feb 01 00:00:00 EST 2023
Neutrophil-derived interleukin-17A participates in neuroinflammation induced by traumatic brain injury.
Neural regeneration research
Xu XJ,Ge QQ,Yang MS,Zhuang Y,Zhang B,Dong JQ,Niu F,Li H,Liu BY
Mon May 01 00:00:00 EDT 2023
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer.
Translational oncology
Júnior RFA,Lira GA,Schomann T,Cavalcante RS,Vilar NF,de Paula RCM,Gomes RF,Chung CK,Jorquera-Cordero C,Vepris O,Chan AB,Cruz LJ
Mon May 01 00:00:00 EDT 2023
S-allylmercaptocysteine promotes anti-tumor immunity by suppressing PD-L1 expression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao J,Sun Y,Gao P,Zhao Z,Wei G
Mon May 01 00:00:00 EDT 2023
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Molecular pharmaceutics
Cheng B,Chu X,Liu R,Ma X,Wang M,Zhang J,Jiao P,Gao Q,Ma W,Zhang Y,Zhao C,Zhou D,Xiao S
Mon Jan 02 00:00:00 EST 2023
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Journal of neuroinflammation
Lun J,Li Y,Gao X,Gong Z,Chen X,Zou J,Zhou C,Huang Y,Zhou B,Huang P,Cao H
Thu Mar 30 00:00:00 EDT 2023
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.
International journal of molecular sciences
Xu X,Deng L,Tang Y,Li J,Zhong T,Hao X,Fan Y,Mu S
Sun Apr 30 00:00:00 EDT 2023
Oxymatrine ameliorates rheumatoid arthritis by regulation of Tfr/Tfh cell balance via the TLR9-MyD88-STAT3 signaling pathway.
Journal of the science of food and agriculture
Cao G,Mao Z,Niu T,Wang P,Yue X,Wang X,Ma A,Zhang Y
Fri Sep 01 00:00:00 EDT 2023
TANK shapes an immunosuppressive microenvironment and predicts prognosis and therapeutic response in glioma.
Frontiers in immunology
Li S,Guo Y,Hu H,Gao N,Yan X,Zhou Q,Liu H
Thu May 25 00:00:00 EDT 2023
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Immunity, inflammation and disease
Yang J,Chen X
Wed Mar 01 00:00:00 EST 2023
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Biochemical pharmacology
Ren Y,Zhu X,Fu K,Zhang H,Zhao W,Lin Y,Fang Q,Wang J,Chen Y,Guo D
Sun Jan 01 00:00:00 EST 2023
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
CNS neuroscience & therapeutics
Shen K,Wu D,Sun B,Zhu Y,Wang H,Zou W,Ma Y,Lu Z
Sun Jan 01 00:00:00 EST 2023
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
International journal of molecular sciences
Wu M,Song D,Li H,Ahmad N,Xu H,Yang X,Wang Q,Cheng X,Deng S,Shu X
Mon May 29 00:00:00 EDT 2023
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
PLoS pathogens
Wang XZ,Wen L,Zhou YP,Huang SN,Yang B,Cheng S,Zeng WB,Mei MJ,Sun JY,Jiang X,Cheng H,Luo MH
Wed Feb 01 00:00:00 EST 2023
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Neuroscience
Deng LJ,Wu D,Yang XF,Li T
Mon Aug 21 00:00:00 EDT 2023
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Neuroscience
Deng LJ,Wu D,Yang XF,Li T
Mon Aug 21 00:00:00 EDT 2023
Quantitative Proteomic Analysis Reveals the Mechanisms of Sinapine Alleviate Macrophage Foaming.
Molecules (Basel, Switzerland)
Liu A,Liao B,Yin S,Ye Z,He M,Li X,Liu Y,Xu Y
Tue Feb 21 00:00:00 EST 2023
Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.
Phytotherapy research : PTR
Ge MX,Niu WX,Bao YY,Lu ZN,He HW
Fri Sep 01 00:00:00 EDT 2023
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Free radical biology & medicine
Liang P,Zhang X,Zhang Y,Wu Y,Song Y,Wang X,Chen T,Liu W,Peng B,Yin J,He F,Fan Y,Han S,He X
Wed Feb 01 00:00:00 EST 2023
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Free radical biology & medicine
Liang P,Zhang X,Zhang Y,Wu Y,Song Y,Wang X,Chen T,Liu W,Peng B,Yin J,He F,Fan Y,Han S,He X
Wed Feb 01 00:00:00 EST 2023
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Free radical biology & medicine
Yao JM,Ying HZ,Zhang HH,Qiu FS,Wu JQ,Yu CH
Wed Feb 01 00:00:00 EST 2023
CARMA3 Deficiency Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysm Development Interacting Between Endoplasmic Reticulum and Mitochondria.
The Canadian journal of cardiology
Yao Y,Cao Y,Xu Y,Chen G,Liu Y,Jiang H,Fan R,Qin W,Wang X,Chai H,Chen X,Qiu Z,Chen W
Sun Oct 01 00:00:00 EDT 2023
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Journal of neuroinflammation
Yuan F,Peng W,Yang Y,Xu J,Liu Y,Xie Y,Huang T,Shi C,Ding Y,Li C,Qin T,Xie S,Zhu F,Lu H,Huang J,Hu J
Fri Jun 30 00:00:00 EDT 2023
HDAC4 mediated LHPP deacetylation enhances its destabilization and promotes the proliferation and metastasis of nasopharyngeal carcinoma.
Cancer letters
Sun X,Zhang K,Peng X,Zhou P,Qu C,Yang L,Shen L
Sun May 28 00:00:00 EDT 2023
HDAC4 mediated LHPP deacetylation enhances its destabilization and promotes the proliferation and metastasis of nasopharyngeal carcinoma.
Cancer letters
Sun X,Zhang K,Peng X,Zhou P,Qu C,Yang L,Shen L
Sun May 28 00:00:00 EDT 2023
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
European journal of pharmacology
Wei P,Lin D,Zhang M,Luo C,Wu X,Deng B,Cui K,Chen Z
Thu Jan 05 00:00:00 EST 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Genes
Zhang H,Xie L,Zhang N,Qi X,Lu T,Xing J,Akhtar MF,Li L,Liu G
Sun Apr 30 00:00:00 EDT 2023
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Molecular immunology
Su W,Zheng X,Zhou H,Yang S,Zhu X
Sat Jul 01 00:00:00 EDT 2023
Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy.
Journal of nanobiotechnology
Jing B,Guo F,An R,Gao Y,Li Y,Xie Y,Wang J,Chen Y,Li H,Gao T,Jin Q,Zhang L,Xie M
Thu Feb 02 00:00:00 EST 2023
NO Release Inhibitory Activity of Flavonoids from Aesculus Wilsonii Seeds through MAPK (P38), NF-κB, and STAT3 Cross-Talk Signaling Pathways.
Planta medica
Cao HN,Ruan JY,Han Y,Zhao W,Zhang Y,Gao C,Wu HH,Ma L,Gao XM,Zhang Y,Wang T
Sun Jan 01 00:00:00 EST 2023
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang Y,Qin X,Yang Y,Li J,Li X,Zou X,Huang Z,Huang S
Sat Jul 01 00:00:00 EDT 2023
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
International immunopharmacology
Yan B,Mao X,Hu S,Wang S,Liu X,Sun J
Thu Jun 01 00:00:00 EDT 2023
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Biomedicines
Qiu Q,Guo G,Guo X,Hu X,Yu T,Liu G,Zhang H,Chen Y,She J
Mon Mar 13 00:00:00 EDT 2023
LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway.
European journal of histochemistry : EJH
Jiang Y,Xu CH,Zhao Y,Ji YH,Wang XT,Liu Y
Mon Jan 16 00:00:00 EST 2023
P4HA1, transcriptionally activated by STAT1, promotes esophageal cancer progression.
Pathology international
Gou W,Yang Y,Shan Q,Xia S,Ma Y
Sat Apr 01 00:00:00 EDT 2023
P4HA1, transcriptionally activated by STAT1, promotes esophageal cancer progression.
Pathology international
Gou W,Yang Y,Shan Q,Xia S,Ma Y
Sat Apr 01 00:00:00 EDT 2023
NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis.
Biochimica et biophysica acta. Molecular cell research
Peng Y,Zhang Y,Luo M,Pan Y,Zhou R,Yan YN,Yi T,Luo F,Wang B,Wang L,Ran C,Wang H
Fri Dec 01 00:00:00 EST 2023
Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer.
Cancer letters
Lu J,Li J,Lin Z,Li H,Lou L,Ding W,Ouyang S,Wu Y,Wen Y,Chen X,Yue P,Wang Y,Liu P,Lu J,Zhang J,Feng W,Zhang X
Wed Jun 28 00:00:00 EDT 2023
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
European journal of pharmacology
Otkur W,Wang J,Hou T,Liu F,Yang R,Li Y,Xiang K,Pei S,Qi H,Lin H,Zhou H,Zhang X,Piao HL,Liang X
Thu Jun 15 00:00:00 EDT 2023
Indolent T-cell lymphoproliferative disorder of gastrointestinal tract with unusual clinical courses: report of 6 cases and literature review.
Virchows Archiv : an international journal of pathology
Fan W,Niu L,He H,Yuan J,Yuan F,Shi X,Wang Y,Chen M,Huang M,Zhou F,Xu J,Chen Q
Sat Apr 01 00:00:00 EDT 2023
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Phytochemistry
Li M,Zhang Y,Han T,Guan L,Fan D,Wu Q,Liu J,Xu Y,Fan Y
Sun Jan 01 00:00:00 EST 2023
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Journal of experimental & clinical cancer research : CR
Liu Y,Xu Q,Deng F,Zheng Z,Luo J,Wang P,Zhou J,Lu X,Zhang L,Chen Z,Zhang Q,Chen Q,Zuo D
Wed Feb 01 00:00:00 EST 2023
Novel pathogenesis of post-traumatic stress disorder studied in transgenic mice.
Journal of psychiatric research
Gong W,Li X,Feng Y,Ji M,Zhang D,Chen B,Wang S,Wu X,Cui L,Li B,Xia M
Mon May 01 00:00:00 EDT 2023
Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
Journal of agricultural and food chemistry
Wan Q,Xu J,Zhu C,Liu X,Tu Y,Lei J,Yu J
Wed Jul 12 00:00:00 EDT 2023
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
British journal of pharmacology
Zhang L,Ma X,Shi R,Zhang L,Zhao R,Duan R,Qin Y,Gao S,Li X,Duan J,Li J
Wed Mar 01 00:00:00 EST 2023
Inhibition of STAT3 phosphorylation by colchicine regulates NLRP3 activation to alleviate sepsis-induced acute lung injury.
Inflammopharmacology
Liu Y,Yang H,Zhu F,Ouyang Y,Pan P
Tue Aug 01 00:00:00 EDT 2023
Inhibition of STAT3 phosphorylation by colchicine regulates NLRP3 activation to alleviate sepsis-induced acute lung injury.
Inflammopharmacology
Liu Y,Yang H,Zhu F,Ouyang Y,Pan P
Tue Aug 01 00:00:00 EDT 2023
Baicalein Attenuates Neuroinflammation in LPS-Treated BV-2 Cells by Inhibiting Glycolysis via STAT3/c-Myc Pathway.
Neurochemical research
Gao L,Liu YX,Zhou YZ,Qin XM
Wed Nov 01 00:00:00 EDT 2023
HIF-1α participates in secondary brain injury through regulating neuroinflammation.
Translational neuroscience
Xu X,Yang M,Zhang B,Dong J,Zhuang Y,Ge Q,Niu F,Liu B
Sun Jan 01 00:00:00 EST 2023
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
Tue Dec 27 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
Tue Dec 27 00:00:00 EST 2022
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Antioxidants (Basel, Switzerland)
Xiong L,Wu H,Zhong T,Luo F,Li Q,Li M,Fan Y
Wed Oct 12 00:00:00 EDT 2022
A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis.
Acta pharmacologica Sinica
Ren ZN,Yang J,Zhang MY,Huang YW,Song DX,Sun X,Pan LL,Sun J
Sun May 01 00:00:00 EDT 2022
A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis.
Acta pharmacologica Sinica
Ren ZN,Yang J,Zhang MY,Huang YW,Song DX,Sun X,Pan LL,Sun J
Sun May 01 00:00:00 EDT 2022
TSLP protects against sepsis-induced liver injury by inducing autophagy via activation of the PI3K/Akt/STAT3 pathway.
Pathology, research and practice
Wang H,Zhu J,Wei L,Wu S,Shang L,Ye X,Li S
Mon Aug 01 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons.
The Journal of clinical investigation
Xie D,Stutz B,Li F,Chen F,Lv H,Sestan-Pesa M,Catarino J,Gu J,Zhao H,Stoddard CE,Carmichael GG,Shanabrough M,Taylor HS,Liu ZW,Gao XB,Horvath TL,Huang Y
Mon Oct 03 00:00:00 EDT 2022
Polygalaxanthone III, an Active Ingredient in Polygala japonica Houtt., Repaired Malassezia-Stimulated Skin Injury via STAT3 Phosphorylated Activation.
Molecules (Basel, Switzerland)
Yang X,Xiong B,Yuan Z,Liao H,Liu X,Wu Y,Zhang S,Xiang Q
Thu Nov 03 00:00:00 EDT 2022
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling.
Journal of translational medicine
Xia Z,Xiao J,Dai Z,Chen Q
Sat Feb 05 00:00:00 EST 2022
Mechanisms of Xiong-Pi-Fang in treating coronary heart disease associated with depression: A systematic pharmacology strategy and in vivo pharmacological validation.
Journal of ethnopharmacology
Deng F,Li X,Tang C,Chen J,Fan B,Liang J,Zhen X,Tao R,Zhang S,Cong Z,Du W,Zhao H,Xu L
Tue Nov 15 00:00:00 EST 2022
Efficacy of WWQ-131, a highly selective JAK2 inhibitor, in mouse models of myeloproliferative neoplasms.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ge H,Wang C,Tian C,Diao Y,Wang W,Ma X,Zhang J,Li H,Zhao Z,Zhu L
Thu Dec 01 00:00:00 EST 2022
Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Li X,Huang S,Zhuo B,Hu J,Shi Y,Zhao J,Tang J,Hu X,Wei S
Fri Apr 08 00:00:00 EDT 2022
Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Li X,Huang S,Zhuo B,Hu J,Shi Y,Zhao J,Tang J,Hu X,Wei S
Fri Apr 08 00:00:00 EDT 2022
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.
Journal of oncology
Nie XH,Qiu S,Xing Y,Xu J,Lu B,Zhao SF,Li YT,Su ZZ
Wed Jan 11 00:00:00 EST 2023
Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways.
International immunopharmacology
Wu Y,Sun Z,Wang T,Wang Y,Zhong L,Kong F
Fri Jul 01 00:00:00 EDT 2022
Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea.
Journal of inflammation research
Wang Y,Wang B,Huang Y,Li Y,Yan S,Xie H,Zhang Y,Li J
Sat Apr 09 00:00:00 EDT 2022
Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea.
Journal of inflammation research
Wang Y,Wang B,Huang Y,Li Y,Yan S,Xie H,Zhang Y,Li J
Sat Apr 09 00:00:00 EDT 2022
Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea.
Journal of inflammation research
Wang Y,Wang B,Huang Y,Li Y,Yan S,Xie H,Zhang Y,Li J
Sat Apr 09 00:00:00 EDT 2022
Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea.
Journal of inflammation research
Wang Y,Wang B,Huang Y,Li Y,Yan S,Xie H,Zhang Y,Li J
Sat Apr 09 00:00:00 EDT 2022
Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells.
Theranostics
Tu J,Xu H,Ma L,Li C,Qin W,Chen X,Yi M,Sun L,Liu B,Yuan X
Thu Mar 10 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
International journal of biological sciences
Fang Y,Dou R,Huang S,Han L,Fu H,Yang C,Song J,Zheng J,Zhang X,Liu K,Xiang Z,Zhang X,Wang S,Xiong B
Thu May 12 00:00:00 EDT 2022
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Nature aging
Liang W,Chen Q,Cheng S,Wei R,Li Y,Yao C,Ouyang Z,Kang D,Chen A,Liu Z,Li K,Bai X,Li Q,Huang B
Sat Oct 01 00:00:00 EDT 2022
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
The Journal of investigative dermatology
Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X
Fri Jul 01 00:00:00 EDT 2022
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
The Journal of investigative dermatology
Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X
Fri Jul 01 00:00:00 EDT 2022
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
The Journal of investigative dermatology
Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X
Fri Jul 01 00:00:00 EDT 2022
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status.
Stem cells international
Dong X,Hu F,Yi J,Zhang Y,Liu C,Geng P,Duan H,Wu CT,Zhang X,Wang H
Fri Oct 28 00:00:00 EDT 2022
Divergent transcriptional regulation of astrocyte reactivity across disorders.
Nature
Burda JE,O'Shea TM,Ao Y,Suresh KB,Wang S,Bernstein AM,Chandra A,Deverasetty S,Kawaguchi R,Kim JH,McCallum S,Rogers A,Wahane S,Sofroniew MV
Wed Jun 01 00:00:00 EDT 2022
Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Mitigates Seizures.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zeng ML,Cheng JJ,Kong S,Yang XL,Jia XL,Cheng XL,Chen L,He FG,Liu YM,Fan YT,Gongga L,Chen TX,Liu WH,He XH,Peng BW
Tue Mar 01 00:00:00 EST 2022
Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Mitigates Seizures.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Zeng ML,Cheng JJ,Kong S,Yang XL,Jia XL,Cheng XL,Chen L,He FG,Liu YM,Fan YT,Gongga L,Chen TX,Liu WH,He XH,Peng BW
Tue Mar 01 00:00:00 EST 2022
Network pharmacology and in vivo experiment-based strategy to investigate mechanisms of JingFangFuZiLiZhong formula for ulcerative colitis.
Annals of medicine
Wang M,Li J,Yin Y,Liu L,Wang Y,Qu Y,Hong Y,Ji S,Zhang T,Wang N,Liu J,Cao X,Zao X,Zhang S
Thu Dec 01 00:00:00 EST 2022
Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gao J,Yao M,Zhang W,Yang B,Yuan G,Liu JX,Zhang Y
Tue Nov 01 00:00:00 EDT 2022
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Frontiers in nutrition
He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L
Sat Jul 16 00:00:00 EDT 2022
Protective effects of progesterone on pulmonary artery smooth muscle cells stimulated with Interleukin 6 via blocking the shuttling and transcriptional function of STAT3.
International immunopharmacology
Hu WP,Xie L,Hao SY,Wu QH,Xiang GL,Li SQ,Liu D
Sat Jan 01 00:00:00 EST 2022
Protective effects of progesterone on pulmonary artery smooth muscle cells stimulated with Interleukin 6 via blocking the shuttling and transcriptional function of STAT3.
International immunopharmacology
Hu WP,Xie L,Hao SY,Wu QH,Xiang GL,Li SQ,Liu D
Sat Jan 01 00:00:00 EST 2022
Protective effects of progesterone on pulmonary artery smooth muscle cells stimulated with Interleukin 6 via blocking the shuttling and transcriptional function of STAT3.
International immunopharmacology
Hu WP,Xie L,Hao SY,Wu QH,Xiang GL,Li SQ,Liu D
Sat Jan 01 00:00:00 EST 2022
IL-10 contributes to gemcitabine resistance in extranodal NK/T-cell lymphoma cells via ABCC4.
Investigational new drugs
Huo J,Fu L,Jin M,Li Z,Zhang M
Wed Jun 01 00:00:00 EDT 2022
The expression of Hexokinase 2 and its hub genes are correlated with the prognosis in glioma.
BMC cancer
Huang Y,Ouyang F,Yang F,Zhang N,Zhao W,Xu H,Yang X
Thu Aug 18 00:00:00 EDT 2022
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
BioMed research international
Liu J,Ding D,Liu F,Chen Y
Thu Mar 31 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes.
International immunopharmacology
Chen X,Zhang Y,Pei J,Zeng X,Yang Y,Zhang Y,Li F,Deng Y
Tue Nov 01 00:00:00 EDT 2022
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhong T,Li M,Wu H,Wang D,Liu J,Xu Y,Fan Y
Wed Jun 01 00:00:00 EDT 2022
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Life sciences
Xu M,Ren L,Fan J,Huang L,Zhou L,Li X,Ye X
Tue Feb 01 00:00:00 EST 2022
Heterogeneity of T cells and macrophages in chlorine-induced acute lung injury in mice using single-cell RNA sequencing.
Inhalation toxicology
Zhao CQ,Liu JZ,Liu MM,Ren XT,Kong DQ,Peng J,Cao M,Liu R,Hai CX,Zhang XD
Wed Nov 23 00:00:00 EST 2022
STAT3-regulated LncRNA LINC00160 mediates cell proliferation and cell metabolism of prostate cancer cells by repressing RCAN1 expression.
Molecular and cellular biochemistry
Zhu W,Sheng D,Shao Y,Zhang Q,Peng Y
Tue Mar 01 00:00:00 EST 2022
MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages.
Molecular biotechnology
Liu M,Cao Y,Hu Y,Zhang Z,Ji S,Shi L,Tao G
Sat Oct 01 00:00:00 EDT 2022
MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages.
Molecular biotechnology
Liu M,Cao Y,Hu Y,Zhang Z,Ji S,Shi L,Tao G
Sat Oct 01 00:00:00 EDT 2022
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Genes & nutrition
Peng M,Fan S,Li J,Zhou X,Liao Q,Tang F,Liu W
Mon Feb 14 00:00:00 EST 2022
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
Glia
Ma Y,Liu H,Ou Z,Qi C,Xing R,Wang S,Han Y,Zhao TJ,Chen Y
Tue Feb 01 00:00:00 EST 2022
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3.
Glia
Ma Y,Liu H,Ou Z,Qi C,Xing R,Wang S,Han Y,Zhao TJ,Chen Y
Tue Feb 01 00:00:00 EST 2022
Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen HL,Lo YH,Lin CL,Lee TH,Leung W,Wang SW,Lin IP,Lin MY,Lee CH
Thu Sep 01 00:00:00 EDT 2022
MDK induces temozolomide resistance in glioblastoma by promoting cancer stem-like properties.
American journal of cancer research
Yu X,Zhou Z,Tang S,Zhang K,Peng X,Zhou P,Zhang M,Shen L,Yang L
Thu Nov 17 00:00:00 EST 2022
Tim-3 downregulation by Toxoplasma gondii infection contributes to decidual dendritic cell dysfunction.
Parasites & vectors
Xie H,Li Z,Zheng G,Yang C,Liu X,Xu X,Ren Y,Wang C,Hu X
Thu Oct 27 00:00:00 EDT 2022
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Life sciences
Zhu M,Niu J,Jiang J,Dong T,Chen Y,Yang X,Liu P
Tue Mar 15 00:00:00 EDT 2022
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Clinics (Sao Paulo, Brazil)
Wang X,Fu Y,Xing Y
Mon Oct 31 00:00:00 EDT 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer.
Frontiers in pharmacology
Chen X,Du Q,Guo H,He Q,Yang B,Ding L
Sat Jul 16 00:00:00 EDT 2022
CXCR1 participates in bone cancer pain induced by Walker 256 breast cancer cells in female rats.
Molecular pain
Xu C,Zhao B,Xu L,Wang Y,Liu B,Xu M,He Q,Ni C,Fu J,Kong M,Lin X,Ni H,Yao M
Fri Apr 01 00:00:00 EDT 2022
Minimally modified low-density lipoprotein upregulates mouse mesenteric arterial 5-HT1B receptor in vivo via activation of the JAK2/STAT3 pathway.
Microvascular research
Tang HX,Lin J,Xu CB,Chen G,Liao YJ,Lei NR,Li J
Sat Jan 01 00:00:00 EST 2022
Anlotinib combined with the PD-L1 blockade exerts the potent anti-tumor immunity in renal cancer treatment.
Experimental cell research
Li J,Cao P,Chen Y,Wang J,Sun X,Chen R,Wang G,Hou J
Mon Aug 01 00:00:00 EDT 2022
The neuroprotective mechanism of lithium after ischaemic stroke.
Communications biology
Chen B,Zhang M,Ji M,Zhang D,Chen B,Gong W,Li X,Zhou Y,Dong C,Wen G,Zhan X,Wu X,Yuan H,Xu E,Xia M,Verkhratsky A,Li B
Thu Feb 03 00:00:00 EST 2022
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.
Toxicology
Pan C,Qin H,Jin H,Chen W,Guo H,Han X
Sat Oct 01 00:00:00 EDT 2022
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Open biology
Xue J,Liao Q,Luo M,Hua C,Zhao J,Yu G,Chen X,Li X,Zhang X,Ran R,Lu F,Wang Y,Qiao L
Fri Apr 01 00:00:00 EDT 2022
Study on the Mechanism of Bu-Shen-He-Mai Granules in Improving Renal Damage of Ageing Spontaneously Hypertensive Rats by Regulating Th17 Cell/Tregs Balance.
Evidence-based complementary and alternative medicine : eCAM
Zhang P,Song XY,Li W,Wei JL,Cui YJ,Qi YZ,Chen XB,Jiang YH,Yang CH
Sat Jul 16 00:00:00 EDT 2022
Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway.
International immunopharmacology
Fan G,Li Y,Liu Y,Suo X,Jia Y,Yang X
Sat Oct 01 00:00:00 EDT 2022
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Pathology, research and practice
Zeng S,Liang Y,Hu H,Wang F,Liang L
Thu Dec 01 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
STAT3 exerts pro-tumor and anti-autophagy roles in cervical cancer.
Diagnostic pathology
Wu L,Shen B,Li J,Zhang H,Zhang K,Yang Y,Zu Z,Shen D,Luo M
Thu Jan 20 00:00:00 EST 2022
Structural optimization of Imidazo[1, 2-a]pyridine derivatives for the treatment of gastric cancer via STAT3 signaling pathway.
European journal of medicinal chemistry
Li H,Ouyang S,Zhang Y,Peng K,Fang W,Liu Z,Wang CY,Zhang X,Wang Y
Thu Dec 15 00:00:00 EST 2022
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Journal of clinical laboratory analysis
Li Z,Xu Q,Huangfu N,Chen X,Zhu J
Sat Jan 01 00:00:00 EST 2022
Novel insights for PI3KC3 in mediating lipid accumulation in yellow catfish Pelteobagrus fulvidraco.
Fish physiology and biochemistry
Zhuo MQ,Chen J,Wu ML,Wang WB
Wed Jun 01 00:00:00 EDT 2022
CircTCF25 serves as a sponge for miR-206 to support proliferation, migration, and invasion of glioma via the Jak2/p-Stat3/CypB axis.
Molecular carcinogenesis
Yin H,Wang H,Wang M,Yan Y,Dong Q,Li Q,Liu Y,Wang X,Guo T,Niu L,Zhang H,Wang B,Yao X,Yuan G,Pan Y
Wed Jun 01 00:00:00 EDT 2022
Activation of STAT6 by intranasal allergens correlated with the development of eosinophilic chronic rhinosinusitis in a mouse model.
International journal of immunopathology and pharmacology
Wei H,Xu L,Sun P,Xing H,Zhu Z,Liu J
Wed Jun 22 00:00:00 EDT 2022
Peripheral Blood-Derived Mesenchymal Stem Cells Modulate Macrophage Plasticity through the IL-10/STAT3 Pathway.
Stem cells international
Pang QM,Yang R,Zhang M,Zou WH,Qian NN,Xu QJ,Chen H,Peng JC,Luo XP,Zhang Q,Zhang T
Sat Jul 16 00:00:00 EDT 2022
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
Archives of biochemistry and biophysics
Song Q,Liao W,He Z,Li D,Dong C,Song C,Yang S
Fri Sep 30 00:00:00 EDT 2022
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Frontiers in pharmacology
Wu B,Huang L,Wang Y,Zeng L,Lin Y,Li J,Wang S,Zhang G,An L
Tue Jan 03 00:00:00 EST 2023
Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.
Molecular nutrition & food research
Jin A,Zhao Y,Yuan Y,Ma S,Chen J,Yang X,Lu S,Sun Q
Tue Feb 01 00:00:00 EST 2022
Boronic Acid: A Novel Pharmacophore Targeting Src Homology 2 (SH2) Domain of STAT3.
Journal of medicinal chemistry
Deng L,Mo J,Zhang Y,Peng K,Li H,Ouyang S,Feng Z,Fang W,Wei J,Rong D,Zhang X,Wang Y
Thu Oct 13 00:00:00 EDT 2022
The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts.
Acta pharmacologica Sinica
Zhong Y,Deng L,Shi S,Huang QY,Ou-Yang SM,Mo JS,Zhu K,Qu XM,Liu PQ,Wang YX,Zhang XL
Fri Apr 01 00:00:00 EDT 2022
The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts.
Acta pharmacologica Sinica
Zhong Y,Deng L,Shi S,Huang QY,Ou-Yang SM,Mo JS,Zhu K,Qu XM,Liu PQ,Wang YX,Zhang XL
Fri Apr 01 00:00:00 EDT 2022
The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts.
Acta pharmacologica Sinica
Zhong Y,Deng L,Shi S,Huang QY,Ou-Yang SM,Mo JS,Zhu K,Qu XM,Liu PQ,Wang YX,Zhang XL
Fri Apr 01 00:00:00 EDT 2022
NCAPD3 promotes prostate cancer progression by up-regulating EZH2 and MALAT1 through STAT3 and E2F1.
Cellular signalling
Jing Z,Liu Q,Xie W,Wei Y,Liu J,Zhang Y,Zuo W,Lu S,Zhu Q,Liu P
Fri Apr 01 00:00:00 EDT 2022
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Redox biology
Ouyang S,Li H,Lou L,Huang Q,Zhang Z,Mo J,Li M,Lu J,Zhu K,Chu Y,Ding W,Zhu J,Lin Z,Zhong L,Wang J,Yue P,Turkson J,Liu P,Wang Y,Zhang X
Wed Jun 01 00:00:00 EDT 2022
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Redox biology
Ouyang S,Li H,Lou L,Huang Q,Zhang Z,Mo J,Li M,Lu J,Zhu K,Chu Y,Ding W,Zhu J,Lin Z,Zhong L,Wang J,Yue P,Turkson J,Liu P,Wang Y,Zhang X
Wed Jun 01 00:00:00 EDT 2022
Regenerating islet-derived protein 3 gamma (Reg3g) ameliorates tacrolimus-induced pancreatic β-cell dysfunction in mice by restoring mitochondrial function.
British journal of pharmacology
Li S,Zhou H,Xie M,Zhang Z,Gou J,Yang J,Tian C,Ma K,Wang CY,Lu Y,Li Q,Peng W,Xiang M
Wed Jun 01 00:00:00 EDT 2022
Glucocorticoids Inhibit EGFR Signaling Activation in Podocytes in Anti-GBM Crescentic Glomerulonephritis.
Frontiers in medicine
Wu X,Ren L,Yang Q,Song H,Tang Q,Zhang M,Zhang J,Tang Z,Shi S
Tue Mar 01 00:00:00 EST 2022
Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Varier KM,Dan G,Liu W,Wu G,Xiao C,Lei H,Ling T,Jiang Y,Chen Y,Ben-David Y,Li Y,Zhang N,Gajendran B,Shen X
Thu Dec 01 00:00:00 EST 2022
COL6A6 inhibits the proliferation and metastasis of non-small cell lung cancer through the JAK signalling pathway.
Translational cancer research
Qiao H,Feng Y,Tang H
Fri Oct 01 00:00:00 EDT 2021
The membrane-associated E3 ubiquitin ligase MARCH3 downregulates the IL-6 receptor and suppresses colitis-associated carcinogenesis.
Cellular & molecular immunology
Lin H,Feng L,Cui KS,Zeng LW,Gao D,Zhang LX,Xu WH,Sun YH,Shu HB,Li S
Wed Dec 01 00:00:00 EST 2021
Effects and Molecular Mechanism of Single-Nucleotide Polymorphisms of MEG3 on Porcine Skeletal Muscle Development.
Frontiers in genetics
Yang R,Liu Y,Cheng Y,Wang C,Song J,Lu G,Feng T,Wang S,Sun X,Meng J,Hao L
Fri Mar 12 00:00:00 EST 2021
Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells.
Frontiers in cell and developmental biology
Chen M,Xiao L,Dai G,Lu P,Zhang Y,Li Y,Ni M,Rui Y
Fri Apr 16 00:00:00 EDT 2021
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Cell & bioscience
Chu Y,Zhu C,Yue C,Peng W,Chen W,He G,Liu C,Lv Y,Gao G,Yao K,Han R,Hu X,Zhang Y,Ye Y
Wed Oct 13 00:00:00 EDT 2021
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
Chemico-biological interactions
Xia Y,Chen J,Liu G,Huang W,Wei X,Wei Z,He Y
Tue May 25 00:00:00 EDT 2021
Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2-STAT3 pathway.
Scientific reports
Yang S,Song Y,Wang Q,Liu Y,Wu Z,Duan X,Zhang Y,Bi X,Geng Y,Chen S,Zhu C
Tue Jun 01 00:00:00 EDT 2021
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Journal of experimental & clinical cancer research : CR
Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C
Tue Aug 24 00:00:00 EDT 2021
Regulation of the Mitochondrion-Fatty Acid Axis for the Metabolic Reprogramming of Chlamydia trachomatis during Treatment with β-Lactam Antimicrobials.
mBio
Shima K,Kaufhold I,Eder T,Käding N,Schmidt N,Ogunsulire IM,Deenen R,Köhrer K,Friedrich D,Isay SE,Grebien F,Klinger M,Richer BC,Günther UL,Deepe GS,Rattei T,Rupp J
Tue Mar 30 00:00:00 EDT 2021
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Journal of clinical biochemistry and nutrition
Guo Y,Ji W,Lu Y,Wang Y
Mon Mar 01 00:00:00 EST 2021
A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC.
Journal of ethnopharmacology
Wang KX,Chen YP,Lu AP,Du GH,Qin XM,Guan DG,Gao L
Mon Jun 28 00:00:00 EDT 2021
PM2.5 promoted lipid accumulation in macrophage via inhibiting JAK2/STAT3 signaling pathways and aggravating the inflammatory reaction.
Ecotoxicology and environmental safety
Yang L,Song Z,Pan Y,Zhao T,Shi Y,Xing J,Ju A,Zhou L,Ye L
Wed Dec 15 00:00:00 EST 2021
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Journal of ethnopharmacology
Zhong T,Feng M,Su M,Wang D,Li Q,Jia S,Luo F,Wang H,Hu E,Yang X,Fan Y
Sun Dec 05 00:00:00 EST 2021
Interleukin-6 participates in human pancreatic stellate cell activation and collagen I production via TGF-β1/Smad pathway.
Cytokine
Zheng M,Li H,Sun L,Brigstock DR,Gao R
Thu Jul 01 00:00:00 EDT 2021
Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis.
Biochemistry and biophysics reports
Qiu Z,Xu F,Wang Z,Yang P,Bu Z,Cheng F,Jiang H,Li L,Zhang F
Wed Dec 01 00:00:00 EST 2021
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ming J,Liu W,Wu H,Li Y,Yang E,Wang Z,Xiao H,Quan R,Hu X
Sun Aug 01 00:00:00 EDT 2021
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Journal of medicinal chemistry
Zhou Z,Li Y,Ma X,Cao B,Peng T,Sheng Y,Peng H,Li R,Cao Y,Xi R,Li F,Wang M,Sun H,Zhang G,Zhang H,Hu K,Xiao W,Wang F
Thu Jun 10 00:00:00 EDT 2021
Qing-Luo-Yin Alleviated Experimental Arthritis in Rats by Disrupting Immune Feedback Between Inflammatory T Cells and Monocytes: Key Evidences from Its Effects on Immune Cell Phenotypes.
Journal of inflammation research
Wang DD,Wu XY,Dong JY,Cheng XP,Gu SF,Olatunji OJ,Li Y,Zuo J
Fri Apr 29 00:00:00 EDT 2022
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Frontiers in molecular biosciences
Yang W,Feng Q,Li M,Su J,Wang P,Wang X,Yin Y,Wang X,Zhao M
Tue Jun 29 00:00:00 EDT 2021
Synthesis of KUE-siRNA Conjugates for Prostate Cancer Cell-Targeted Gene Silencing.
Chembiochem : a European journal of chemical biology
Yang C,Ma D,Lu L,Yang X,Xi Z
Fri Oct 01 00:00:00 EDT 2021
STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration.
Frontiers in molecular biosciences
Xue Y,Zhou Y,Bao W,Fu Q,Hao H,Han L,Zhang X,Tian X,Zhang M
Fri Nov 12 00:00:00 EST 2021
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
International immunopharmacology
Meng Z,Liu X,Li T,Fang T,Cheng Y,Han L,Sun B,Chen L
Sat May 01 00:00:00 EDT 2021
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
Journal of clinical laboratory analysis
Xu Y,Chen J,He G,Zhang Y
Wed Sep 01 00:00:00 EDT 2021
SETD8 potentiates constitutive ERK1/2 activation via epigenetically silencing DUSP10 expression in pancreatic cancer.
Cancer letters
Liu M,Qin Y,Hu Q,Liu W,Ji S,Xu W,Fan G,Ye Z,Zhang Z,Xu X,Yu X,Zhuo Q
Sun Feb 28 00:00:00 EST 2021
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Frontiers in pharmacology
Yang W,Su J,Li M,Li T,Wang X,Zhao M,Hu X
Fri Nov 05 00:00:00 EDT 2021
Highly Expressed CYBRD1 Associated with Glioma Recurrence Regulates the Immune Response of Glioma Cells to Interferon.
Evidence-based complementary and alternative medicine : eCAM
Qing M,Zhou J,Chen W,Cheng L
Sat Jul 31 00:00:00 EDT 2021
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway.
Bioscience, biotechnology, and biochemistry
Liang J,Yuan H,Xu L,Wang F,Bao X,Yan Y,Wang H,Zhang C,Jin R,Ma L,Zhang J,Huri L,Su X,Xiao R,Ma Y
Wed Mar 24 00:00:00 EDT 2021
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Life sciences
Liu S,Liu J,Wang Y,Deng L,Chen S,Wang X,Zuo T,Hu Q,Rao J,Wang Q,Dong Z
Sat May 15 00:00:00 EDT 2021
LincRNA-Cox2 regulates IL6/JAK3/STAT3 and NF-κB P65 pathway activation in Listeria monocytogenes-infected RAW264.7 cells.
International journal of medical microbiology : IJMM
Zhu Y,Lu Y,Yuan L,Ling W,Jiang X,Chen S,Hu B
Thu Jul 01 00:00:00 EDT 2021
Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264.7 macrophages: A quantibody array analysis.
Journal of pharmacological sciences
Wu Y,Fu H,Yang X,Leng F,Huang Y,Deng H,Xiang Q,Zhang S
Fri Oct 01 00:00:00 EDT 2021
Concentrated growth factor regulates the macrophage-mediated immune response.
Regenerative biomaterials
Luo H,Liu W,Zhou Y,Jiang X,Liu Y,Yang Q,Shao L
Fri Oct 01 00:00:00 EDT 2021
HOTAIR/miR-17-5p Axis is Involved in the Propofol-Mediated Cardioprotection Against Ischemia/Reperfusion Injury.
Clinical interventions in aging
Chen J,Li X,Zhao F,Hu Y
Tue Jun 15 00:00:00 EDT 2021
PDGF-BB promotes vascular smooth muscle cell migration by enhancing Pim-1 expression via inhibiting miR-214.
Annals of translational medicine
Zhou J,Shao L,Yu J,Huang J,Feng Q
Wed Dec 01 00:00:00 EST 2021
Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis.
Pharmaceutical biology
Zhou Y,Wu R,Cai FF,Zhou WJ,Lu YY,Zhang H,Chen QL,Sun MY,Su SB
Wed Dec 01 00:00:00 EST 2021
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Viruses
Wang Q,Xin Q,Shang W,Wan W,Xiao G,Zhang LK
Tue May 25 00:00:00 EDT 2021
Traffic-related PM2.5 and diverse constituents disturb the balance of Th17/Treg cells by STAT3/RORγt-STAT5/Foxp3 signaling pathway in a rat model of asthma.
International immunopharmacology
Wang C,Wang D,Zhao H,Wang J,Liu N,Shi H,Tian J,Wang X,Zhang Z
Thu Jul 01 00:00:00 EDT 2021
Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation by Inhibiting Gal-3/Gal-3BP/IL6 Axis.
Frontiers in pharmacology
Zhou Y,Yan H,Zhou Q,Feng R,Wang P,Yang F,Zhang Y,Yuan Z,Zhai B
Fri Nov 19 00:00:00 EST 2021
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Journal of Zhejiang University. Science. B
Xu A,Lee J,Zhao Y,Wang Y,Li X,Xu P
Thu Jul 15 00:00:00 EDT 2021
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Xin Y,Shang X,Sun X,Liu Y,Xu G,Xue G
Wed Apr 27 00:00:00 EDT 2022
Effect of Shenkang on renal fibrosis and activation of renal interstitial fibroblasts through the JAK2/STAT3 pathway.
BMC complementary medicine and therapies
Qin T,Wu Y,Liu T,Wu L
Wed Jan 06 00:00:00 EST 2021
Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway.
Experimental and therapeutic medicine
Peng S,Shen L,Tian MX,Li HM,Wang SS
Mon Feb 01 00:00:00 EST 2021
Discovery of a PROTAC targeting ALK with in vivo activity.
European journal of medicinal chemistry
Yan G,Zhong X,Yue L,Pu C,Shan H,Lan S,Zhou M,Hou X,Yang J,Li R
Mon Feb 15 00:00:00 EST 2021
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
ACS applied materials & interfaces
Chen A,Yang F,Kuang J,Xiong Y,Mi BB,Zhou Y,Hu JJ,Song SJ,Wan T,Wan ZZ,Huang HY,Li XR,Song W,Qiu WX
Wed Sep 29 00:00:00 EDT 2021
Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.
Cell death discovery
Yin P,Li D,Zhao Q,Cai M,Wu Z,Shi Y,Su L
Tue Dec 14 00:00:00 EST 2021
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Frontiers in cellular and infection microbiology
Li T,Cui L,Xu X,Zhang H,Jiang Y,Ren L,Yang C,Liu X,Hu X
Fri Jun 18 00:00:00 EDT 2021
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Journal of neuroinflammation
Ma X,Qin C,Chen M,Yu HH,Chu YH,Chen TJ,Bosco DB,Wu LJ,Bu BT,Wang W,Tian DS
Wed Sep 15 00:00:00 EDT 2021
Plasma‑derived exosomal pyruvate kinase isoenzyme type M2 accelerates the proliferation and motility of oesophageal squamous cell carcinoma cells.
Oncology reports
Yang L,Zheng S,Liu Q,Liu T,Zhang Q,Han X,Tuerxun A,Lu X
Fri Oct 01 00:00:00 EDT 2021
ELK3: A New Molecular Marker for the Diagnosis and Prognosis of Glioma.
Frontiers in oncology
Liu Z,Ren Z,Zhang C,Qian R,Wang H,Wang J,Zhang W,Liu B,Lian X,Wang Y,Guo Y,Gao Y
Tue Jan 04 00:00:00 EST 2022
Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
European journal of medicinal chemistry
Huang Q,Zhong Y,Li B,Ouyang S,Deng L,Mo J,Shi S,Lv N,Wu R,Liu P,Hu W,Zhang X,Wang Y
Tue Oct 05 00:00:00 EDT 2021
IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Clinical & translational immunology
Li J,Cheng L,Jia H,Liu C,Wang S,Liu Y,Shen Y,Wu S,Meng F,Zheng B,Yang C,Jiang W
Thu Apr 28 00:00:00 EDT 2022
Autophagy regulates functional differentiation of mammary epithelial cells.
Autophagy
Elswood J,Pearson SJ,Payne HR,Barhoumi R,Rijnkels M,W Porter W
Mon Feb 01 00:00:00 EST 2021
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Yuan C,Yang D,Ma J,Yang J,Xue J,Song F,Liu X
Fri Aug 28 00:00:00 EDT 2020
MicroRNA-449b-3p inhibits epithelial-mesenchymal transition by targeting IL-6 and through the JAK2/STAT3 signaling pathway in non-small cell lung cancer.
Experimental and therapeutic medicine
Cai K,Li HX,Li PP,Guo ZJ,Yang Y
Wed Apr 01 00:00:00 EDT 2020
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
ACS chemical neuroscience
Lv R,Du L,Zhou F,Yuan X,Liu X,Zhang L
Wed Oct 21 00:00:00 EDT 2020
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
Journal of ethnopharmacology
Zhang M,Fan H,Tan S,Tang Q,Liu X,Zuo D,Liao Y,Nan Z,Tan C
Mon Apr 06 00:00:00 EDT 2020
Phosphorylated STAT3 suppresses microRNA-19b/1281 to aggravate lung injury in mice with type 2 diabetes mellitus-associated pulmonary tuberculosis.
Journal of cellular and molecular medicine
Wang X,Lin Y,Liang Y,Ye Y,Wang D,Tai A,Wu S,Pan J
Tue Dec 01 00:00:00 EST 2020
Proteomics analysis of tumor exosomes reveals vital pathways of Jinfukang inhibiting circulating tumor cells metastasis in lung cancer.
Journal of ethnopharmacology
Que ZJ,Luo B,Wang CT,Qian FF,Jiang Y,Li Y,Han XH,Li HG,Liu JX,Tian JH
Sun Jun 28 00:00:00 EDT 2020
WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation.
Molecules and cells
Hu J,Pi S,Xiong M,Liu Z,Huang X,An R,Zhang T,Yuan B
Mon Aug 31 00:00:00 EDT 2020
IL-6 induces tumor suppressor protein tyrosine phosphatase receptor type D by inhibiting miR-34a to prevent IL-6 signaling overactivation.
Molecular and cellular biochemistry
Zhang F,Wang B,Qin T,Wang L,Zhang Q,Lu Y,Song B,Yu X,Li L
Thu Oct 01 00:00:00 EDT 2020
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Oxidative medicine and cellular longevity
Wang W,Hu X,Xia Z,Liu Z,Zhong Z,Lu Z,Liu A,Ye S,Cao Q,Wang Y,Zhu F,Ye Q
Wed Dec 16 00:00:00 EST 2020
Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3.
Cancers
Sogawa C,Eguchi T,Tran MT,Ishige M,Trin K,Okusha Y,Taha EA,Lu Y,Kawai H,Sogawa N,Takigawa M,Calderwood SK,Okamoto K,Kozaki KI
Mon Feb 24 00:00:00 EST 2020
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Oncology research
Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H
Tue Sep 01 00:00:00 EDT 2020
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
International journal of biological sciences
Zhang N,Zhang Y,You S,Tian Y,Lu S,Cao L,Sun Y
Thu Feb 04 00:00:00 EST 2021
Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang J,Sun Z,Lin N,Lu W,Huang X,Weng J,Sun S,Zhang C,Yang Q,Zhou G,Guo H,Chi J
Thu Oct 01 00:00:00 EDT 2020
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.
Oncology letters
Liang JX,Gao W,Zeng XW,Cheng GP,Cai L,Tao KY,Yang X
Sun Nov 01 00:00:00 EDT 2020
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Cell communication and signaling : CCS
Liu Q,Yang C,Wang S,Shi D,Wei C,Song J,Lin X,Dou R,Bai J,Xiang Z,Huang S,Liu K,Xiong B
Mon Mar 30 00:00:00 EDT 2020
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Cell communication and signaling : CCS
Liu Q,Yang C,Wang S,Shi D,Wei C,Song J,Lin X,Dou R,Bai J,Xiang Z,Huang S,Liu K,Xiong B
Mon Mar 30 00:00:00 EDT 2020
Dexmedetomidine alleviates neurobehavioral impairments and myelination deficits following lipopolysaccharide exposure in early postnatal rats.
Life sciences
Wu Z,Xue H,Zhang Y,Zhao P
Tue Dec 15 00:00:00 EST 2020
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Aging
Lin Y,Jin H,Wu X,Jian Z,Zou X,Huang J,Guan R,Wei X
Mon Jul 27 00:00:00 EDT 2020
CD63+ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao Y,Li X,Zeng C,Liu C,Hao Q,Li W,Zhang K,Zhang W,Wang S,Zhao H,Fan D,Li M,Zhang Y,Zhang W,Zhang C
Sun Nov 01 00:00:00 EDT 2020
CD63+ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao Y,Li X,Zeng C,Liu C,Hao Q,Li W,Zhang K,Zhang W,Wang S,Zhao H,Fan D,Li M,Zhang Y,Zhang W,Zhang C
Sun Nov 01 00:00:00 EDT 2020
Hispidulin Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia and Attenuates the Activation of Akt, NF-κB, and STAT3 Pathway.
Neurotoxicity research
Yu CI,Cheng CI,Kang YF,Chang PC,Lin IP,Kuo YH,Jhou AJ,Lin MY,Chen CY,Lee CH
Mon Jun 01 00:00:00 EDT 2020
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.
Aging
Shi C,Yang J,Hu L,Liao B,Qiao L,Shen W,Xie F,Zhu G
Mon Aug 03 00:00:00 EDT 2020
IL-27 Rα+ cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Journal of cellular and molecular medicine
Zhao S,Liang T,Zhang C,Shi D,Jiang W,Su C,Hou G
Tue Sep 01 00:00:00 EDT 2020
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Oncology letters
Song X,Yang W,Wu C,Han Y,Lu Y
Tue Sep 01 00:00:00 EDT 2020
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Frontiers in pharmacology
Wan YM,Wu HM,Li YH,Xu ZY,Yang JH,Liu C,He YF,Wang MJ,Wu XN,Zhang Y
Fri Nov 03 00:00:00 EDT 2023
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Experimental and molecular pathology
Tian C,Gao F,Li X,Li Z
Wed Apr 01 00:00:00 EDT 2020
Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice.
Food & function
Huang Y,Qiu L,Mi X,Zhang Z,Xu D,Tao X,Xing K,Wu Q,Wei H
Thu Apr 30 00:00:00 EDT 2020
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Frontiers in pharmacology
Zhou XL,Yang J,Qu XJ,Meng J,Miao RR,Cui SX
Sun Apr 17 00:00:00 EDT 2022
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
Frontiers in psychiatry
Li X,Qiu W,Li N,Da X,Ma Q,Hou Y,Wang T,Song M,Chen J
Mon Sep 28 00:00:00 EDT 2020
Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.
American journal of translational research
Chu P,Wang S,Zhu X,Yang Y,Li H,Tesfaldet T,Shopit A,Yang Y,Ma X,Peng J,Tang Z,Sun Z
Wed Dec 16 00:00:00 EST 2020
ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII.
Acta pharmacologica Sinica
Xiong Y,Chang LL,Tran B,Dai T,Zhong R,Mao YC,Zhu YZ
Sat Feb 01 00:00:00 EST 2020
ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII.
Acta pharmacologica Sinica
Xiong Y,Chang LL,Tran B,Dai T,Zhong R,Mao YC,Zhu YZ
Sat Feb 01 00:00:00 EST 2020
AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Cell death & disease
Chen M,Li Y,Xiao L,Dai G,Lu P,Wang Y,Rui Y
Wed Mar 18 00:00:00 EDT 2020
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Journal of cellular and molecular medicine
Zhang Y,You S,Tian Y,Lu S,Cao L,Sun Y,Zhang N
Sat Aug 01 00:00:00 EDT 2020
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.
International immunopharmacology
Zhang Y,Cong X,Li Z,Xue Y
Wed Jan 01 00:00:00 EST 2020
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
Aging
Dai H,Li M,Yang W,Sun X,Wang P,Wang X,Su J,Wang X,Hu X,Zhao M
Fri Jun 12 00:00:00 EDT 2020
Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (Danio rerio).
Nanotoxicology
Xiong G,Deng Y,Liao X,Zhang J,Cheng B,Cao Z,Lu H
Mon Jun 01 00:00:00 EDT 2020
Inhibition of RELM-β prevents hypoxia-induced overproliferation of human pulmonary artery smooth muscle cells by reversing PLC-mediated KCNK3 decline.
Life sciences
Han L,Song N,Hu X,Zhu A,Wei X,Liu J,Yuan S,Mao W,Chen X
Wed Apr 01 00:00:00 EDT 2020
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Frontiers in oncology
Li X,Liu Y,Wang Y,Li X,Liu X,Guo M,Tan Y,Qin X,Wang X,Jiang M
Mon Sep 28 00:00:00 EDT 2020
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
Molecular and cellular biochemistry
Liu Y,Che G,Di Z,Sun W,Tian J,Ren M
Wed Jan 01 00:00:00 EST 2020
Parathyroid hormone (1-34) ameliorates cartilage degeneration and subchondral bone deterioration in collagenase-induced osteoarthritis model in mice.
Bone & joint research
Shao LT,Gou Y,Fang JK,Hu YP,Lian QQ,Zhang YY,Wang YD,Tian FM,Zhang L
Thu Oct 01 00:00:00 EDT 2020
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Oxidative medicine and cellular longevity
Jiang X,Ruan XL,Xue YX,Yang S,Shi M,Wang LN
Mon Sep 21 00:00:00 EDT 2020
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Oxidative medicine and cellular longevity
Jiang X,Ruan XL,Xue YX,Yang S,Shi M,Wang LN
Mon Sep 21 00:00:00 EDT 2020
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Oxidative medicine and cellular longevity
Jiang X,Ruan XL,Xue YX,Yang S,Shi M,Wang LN
Mon Sep 21 00:00:00 EDT 2020
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Oxidative medicine and cellular longevity
Jiang X,Ruan XL,Xue YX,Yang S,Shi M,Wang LN
Mon Sep 21 00:00:00 EDT 2020
Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells.
Technology in cancer research & treatment
Chen M,Ye A,Wei J,Wang R,Poon K
Mon Nov 29 00:00:00 EST 2021
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Aging cell
Xu Q,Long Q,Zhu D,Fu D,Zhang B,Han L,Qian M,Guo J,Xu J,Cao L,Chin YE,Coppé JP,Lam EW,Campisi J,Sun Y
Sun Dec 01 00:00:00 EST 2019
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Journal of cellular and molecular medicine
Wang J,Zhang C,Li C,Zhao D,Li S,Ma L,Cui Y,Wei X,Zhao Y,Gao Y
Wed May 01 00:00:00 EDT 2019
STAT3-Activated Long Non-Coding RNA Lung Cancer Associated Transcript 1 Drives Cell Proliferation, Migration, and Invasion in Hepatoblastoma Through Regulation of the miR-301b/STAT3 Axis.
Human gene therapy
Wang X,Guo S,Zhao R,Liu Y,Yang G
Sat Jun 01 00:00:00 EDT 2019
STAT3-Activated Long Non-Coding RNA Lung Cancer Associated Transcript 1 Drives Cell Proliferation, Migration, and Invasion in Hepatoblastoma Through Regulation of the miR-301b/STAT3 Axis.
Human gene therapy
Wang X,Guo S,Zhao R,Liu Y,Yang G
Sat Jun 01 00:00:00 EDT 2019
MicroRNA-204-5p suppresses IL6-mediated inflammatory response and chemokine generation in HK-2 renal tubular epithelial cells by targeting IL6R.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Li H,Wang J,Liu X,Cheng Q
Mon Apr 01 00:00:00 EDT 2019
MicroRNA-204-5p suppresses IL6-mediated inflammatory response and chemokine generation in HK-2 renal tubular epithelial cells by targeting IL6R.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Li H,Wang J,Liu X,Cheng Q
Mon Apr 01 00:00:00 EDT 2019
Role of PUMA in the methamphetamine-induced migration of microglia.
Metabolic brain disease
Zhao L,Du L,Zhang Y,Chao J,Duan M,Yao H,Shen C,Zhang Y
Fri Feb 01 00:00:00 EST 2019
Role of PUMA in the methamphetamine-induced migration of microglia.
Metabolic brain disease
Zhao L,Du L,Zhang Y,Chao J,Duan M,Yao H,Shen C,Zhang Y
Fri Feb 01 00:00:00 EST 2019
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gene
Gao J,Guo Y,Chen Y,Zhou J,Liu Y,Su P
Mon May 20 00:00:00 EDT 2019
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Oxidative medicine and cellular longevity
Wang G,Xu B,Shi F,Du M,Li Y,Yu T,Chen L
Mon Dec 16 00:00:00 EST 2019
Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146.
Frontiers in immunology
Zhang L,Fu Y,Wang H,Guan Y,Zhu W,Guo M,Zheng N,Wu Z
Wed Sep 09 00:00:00 EDT 2020
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gao L,Sang JZ,Cao H
Tue Oct 01 00:00:00 EDT 2019
CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Frontiers in oncology
Huang Q,Li S,Zhang L,Qiao X,Zhang Y,Zhao X,Xiao G,Li Z
Tue Sep 29 00:00:00 EDT 2020
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
Biotechnology progress
Huang CH,Lei KF,Tsang NM
Wed May 01 00:00:00 EDT 2019
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.
International journal of molecular sciences
Wang H,Yuan M,Wang S,Zhang L,Zhang R,Zou X,Wang X,Chen D,Wu Z
Mon Sep 30 00:00:00 EDT 2019
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.
International journal of molecular sciences
Wang H,Yuan M,Wang S,Zhang L,Zhang R,Zou X,Wang X,Chen D,Wu Z
Mon Sep 30 00:00:00 EDT 2019
Hedyotis diffusa Willd. inhibits VEGF‑C‑mediated lymphangiogenesis in colorectal cancer via multiple signaling pathways.
Oncology reports
Li H,Lai Z,Yang H,Peng J,Chen Y,Lin J
Sun Sep 01 00:00:00 EDT 2019
STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses.
Cell death and differentiation
Avalle L,Camporeale A,Morciano G,Caroccia N,Ghetti E,Orecchia V,Viavattene D,Giorgi C,Pinton P,Poli V
Wed May 01 00:00:00 EDT 2019
Argininosuccinate synthase 1 suppresses cancer cell invasion by inhibiting STAT3 pathway in hepatocellular carcinoma.
Acta biochimica et biophysica Sinica
Tao X,Zuo Q,Ruan H,Wang H,Jin H,Cheng Z,Lv Y,Qin W,Wang C
Fri Mar 01 00:00:00 EST 2019
IL-27 Promotes Human Placenta-Derived Mesenchymal Stromal Cell Ability To Induce the Generation of CD4+IL-10+IFN-γ+ T Cells via the JAK/STAT Pathway in the Treatment of Experimental Graft-versus-Host Disease.
Journal of immunology (Baltimore, Md. : 1950)
Yi J,Chen Z,Xu F,Wang Z,Zhang A,Liu T,Zhao N,Xiong Y,Jiang G,Ma J,Luan X
Fri Feb 15 00:00:00 EST 2019
Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway.
Journal of experimental & clinical cancer research : CR
Ren D,Zhao J,Sun Y,Li D,Meng Z,Wang B,Fan P,Liu Z,Jin X,Wu H
Mon Dec 09 00:00:00 EST 2019
Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.
Scientific reports
Li Z,Yu Y,Wang M,Xu H,Han B,Jiang P,Ma H,Li Y,Tian C,Zhou D,Li X,Ye X
Wed Jan 16 00:00:00 EST 2019
Vasorin stimulates malignant progression and angiogenesis in glioma.
Cancer science
Liang W,Guo B,Ye J,Liu H,Deng W,Lin C,Zhong X,Wang L
Thu Aug 01 00:00:00 EDT 2019
Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation.
Theranostics
Huang S,Wang LL,Xue NN,Li C,Guo HH,Ren TK,Zhan Y,Li WB,Zhang J,Chen XG,Han YX,Zhang JL,Jiang JD
Fri Jul 24 00:00:00 EDT 2020
A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella.
Medical science monitor : international medical journal of experimental and clinical research
Bei M,Tian F,Liu N,Zheng Z,Cao X,Zhang H,Wang Y,Xiao Y,Dai M,Zhang L
Sat Apr 13 00:00:00 EDT 2019
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT.
Journal of cellular biochemistry
Ma R,Liu Q,Zheng S,Liu T,Tan D,Lu X
Mon Jul 01 00:00:00 EDT 2019
P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice.
International journal of biological sciences
Li T,Wang F,Dang Y,Dong J,Zhang Y,Zhang C,Liu P,Gao Y,Wang X,Yang S,Lu S
Mon Apr 27 00:00:00 EDT 2020
P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice.
International journal of biological sciences
Li T,Wang F,Dang Y,Dong J,Zhang Y,Zhang C,Liu P,Gao Y,Wang X,Yang S,Lu S
Mon Apr 27 00:00:00 EDT 2020
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation.
Molecular and cellular probes
Lou D,Wang J,Wang X
Sun Dec 01 00:00:00 EST 2019
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Human gene therapy
Xu Y,Wang X,Guo B,Wang D,Kalvakolanu DV,Chen X,Tang J,Zhang L,Yang Q
Fri Nov 01 00:00:00 EDT 2019
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Colloids and surfaces. B, Biointerfaces
Zhu Y,Meng Y,Zhao Y,Zhu J,Xu H,Zhang E,Shi L,Du L,Liu G,Zhang C,Xu X,Kang X,Zhen Y,Zhang S
Mon Jul 01 00:00:00 EDT 2019
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cancer research
Cao D,Qi Z,Pang Y,Li H,Xie H,Wu J,Huang Y,Zhu Y,Shen Y,Zhu Y,Dai B,Hu X,Ye D,Wang Z
Wed May 15 00:00:00 EDT 2019
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
Journal of cellular biochemistry
Wang S,Zhang S,He Y,Huang X,Hui Y,Tang Y
Sun Sep 01 00:00:00 EDT 2019
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Cell proliferation
Wang Y,He G,Tang H,Shi Y,Kang X,Lyu J,Zhu M,Zhou M,Yang M,Mu M,Chen W,Zhou B,Zhang J,Tang K
Mon Jul 01 00:00:00 EDT 2019
Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemia.
Journal of pharmacological sciences
Ma W,Xiang Y,Yang R,Zhang T,Xu J,Wu Y,Liu X,Xiang K,Zhao H,Liu Y,Si Y
Mon Apr 01 00:00:00 EDT 2019
Paper/polymer composited microfluidic platform for screening cell viability and protein expression under a chemical gradient environment.
Talanta
Lei KF,Goh A,Huang CH
Sun Dec 01 00:00:00 EST 2019
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Frontiers in oncology
Dai X,Zhang S,Cheng H,Cai D,Chen X,Huang Z
Sat Oct 14 00:00:00 EDT 2023
Effect of Konjac Mannan Oligosaccharides on Glucose Homeostasis via the Improvement of Insulin and Leptin Resistance In Vitro and In Vivo.
Nutrients
Zhu D,Yan Q,Li Y,Liu J,Liu H,Jiang Z
Wed Jul 24 00:00:00 EDT 2019
SIRT4 enhances the sensitivity of ER-positive breast cancer to tamoxifen by inhibiting the IL-6/STAT3 signal pathway.
Cancer medicine
Xing J,Li J,Fu L,Gai J,Guan J,Li Q
Fri Nov 01 00:00:00 EDT 2019
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation.
Brain, behavior, and immunity
Xin D,Chu X,Bai X,Ma W,Yuan H,Qiu J,Liu C,Li T,Zhou X,Chen W,Liu D,Wang Z
Mon Oct 01 00:00:00 EDT 2018
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation.
Brain, behavior, and immunity
Xin D,Chu X,Bai X,Ma W,Yuan H,Qiu J,Liu C,Li T,Zhou X,Chen W,Liu D,Wang Z
Mon Oct 01 00:00:00 EDT 2018
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
Hypertension (Dallas, Tex. : 1979)
Chen X,Tong C,Li H,Peng W,Li R,Luo X,Ge H,Ran Y,Li Q,Liu Y,Xiong X,Bai Y,Zhang H,Baker PN,Liu X,Qi H
Thu Mar 01 00:00:00 EST 2018
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
Hypertension (Dallas, Tex. : 1979)
Chen X,Tong C,Li H,Peng W,Li R,Luo X,Ge H,Ran Y,Li Q,Liu Y,Xiong X,Bai Y,Zhang H,Baker PN,Liu X,Qi H
Thu Mar 01 00:00:00 EST 2018
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Cancer letters
Song J,Chen Z,Geng T,Wang M,Yi S,Liu K,Zhou W,Gao J,Song W,Tang H
Mon Oct 01 00:00:00 EDT 2018
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon.
Cancer letters
Song J,Chen Z,Geng T,Wang M,Yi S,Liu K,Zhou W,Gao J,Song W,Tang H
Mon Oct 01 00:00:00 EDT 2018
CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition.
Cancer letters
Ma Y,Zhang H,Xiong C,Liu Z,Xu Q,Feng J,Zhang J,Wang Z,Yan X
Tue Aug 28 00:00:00 EDT 2018
CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition.
Cancer letters
Ma Y,Zhang H,Xiong C,Liu Z,Xu Q,Feng J,Zhang J,Wang Z,Yan X
Tue Aug 28 00:00:00 EDT 2018
The relationship between lncRNA PCGEM1 and STAT3 during the occurrence and development of endometrial carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li Q,Shen F,Zhao L
Thu Nov 01 00:00:00 EDT 2018
The relationship between lncRNA PCGEM1 and STAT3 during the occurrence and development of endometrial carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li Q,Shen F,Zhao L
Thu Nov 01 00:00:00 EDT 2018
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Long Y,Li S,Qin J,Xie L,Gan L,Jie F,Wu Y,Li Y,Du Q
Sat Sep 01 00:00:00 EDT 2018
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Long Y,Li S,Qin J,Xie L,Gan L,Jie F,Wu Y,Li Y,Du Q
Sat Sep 01 00:00:00 EDT 2018
A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.
European journal of medicinal chemistry
Liu S,Gao X,Zhang L,Qin S,Wei M,Liu N,Zhao R,Li B,Meng Y,Lin G,Lu C,Liu X,Xie M,Liu T,Zhou H,Qi M,Yang G,Yang C
Sun Aug 05 00:00:00 EDT 2018
A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.
European journal of medicinal chemistry
Liu S,Gao X,Zhang L,Qin S,Wei M,Liu N,Zhao R,Li B,Meng Y,Lin G,Lu C,Liu X,Xie M,Liu T,Zhou H,Qi M,Yang G,Yang C
Sun Aug 05 00:00:00 EDT 2018
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Journal of cellular physiology
Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z
Mon Jan 01 00:00:00 EST 2018
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Journal of cellular physiology
Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z
Mon Jan 01 00:00:00 EST 2018
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
International immunopharmacology
Wu XY,Tian F,Su MH,Wu M,Huang Y,Hu LH,Jin L,Zhu XJ
Thu Nov 01 00:00:00 EDT 2018
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
International immunopharmacology
Wu XY,Tian F,Su MH,Wu M,Huang Y,Hu LH,Jin L,Zhu XJ
Thu Nov 01 00:00:00 EDT 2018
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
International immunopharmacology
Wu XY,Tian F,Su MH,Wu M,Huang Y,Hu LH,Jin L,Zhu XJ
Thu Nov 01 00:00:00 EDT 2018
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway.
International immunopharmacology
Wu XY,Tian F,Su MH,Wu M,Huang Y,Hu LH,Jin L,Zhu XJ
Thu Nov 01 00:00:00 EDT 2018
Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway.
International journal of molecular medicine
Ke M,He Q,Hong D,Li O,Zhu M,Ou WB,He Y,Wu Y
Sun Jul 01 00:00:00 EDT 2018
Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway.
International journal of molecular medicine
Ke M,He Q,Hong D,Li O,Zhu M,Ou WB,He Y,Wu Y
Sun Jul 01 00:00:00 EDT 2018
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Environmental science and pollution research international
Xu J,Zhou L,Wang S,Zhu J,Liu T,Jia Y,Sun D,Chen H,Wang Q,Xu F,Zhang Y,Liu H,Zhang T,Ye L
Thu Feb 01 00:00:00 EST 2018
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Environmental science and pollution research international
Xu J,Zhou L,Wang S,Zhu J,Liu T,Jia Y,Sun D,Chen H,Wang Q,Xu F,Zhang Y,Liu H,Zhang T,Ye L
Thu Feb 01 00:00:00 EST 2018
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Environmental science and pollution research international
Xu J,Zhou L,Wang S,Zhu J,Liu T,Jia Y,Sun D,Chen H,Wang Q,Xu F,Zhang Y,Liu H,Zhang T,Ye L
Thu Feb 01 00:00:00 EST 2018
Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats.
Environmental science and pollution research international
Xu J,Zhou L,Wang S,Zhu J,Liu T,Jia Y,Sun D,Chen H,Wang Q,Xu F,Zhang Y,Liu H,Zhang T,Ye L
Thu Feb 01 00:00:00 EST 2018
Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation.
Drug metabolism and disposition: the biological fate of chemicals
Okumura H,Nakanishi A,Hashita T,Iwao T,Matsunaga T
Thu Nov 01 00:00:00 EDT 2018
Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation.
Drug metabolism and disposition: the biological fate of chemicals
Okumura H,Nakanishi A,Hashita T,Iwao T,Matsunaga T
Thu Nov 01 00:00:00 EDT 2018
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Molecular medicine reports
Wang AL,Li Y,Zhao Q,Fan LQ
Fri Jun 01 00:00:00 EDT 2018
Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Molecular medicine reports
Wang AL,Li Y,Zhao Q,Fan LQ
Fri Jun 01 00:00:00 EDT 2018
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Molecular medicine reports
Deng G,Li K,Chen S,Chen P,Zheng H,Yu B,Zhang K
Sat Dec 01 00:00:00 EST 2018
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
Biochemical and biophysical research communications
Du Y,Zhang W,Liu S,Feng X,Gao F,Liu Q
Mon Sep 03 00:00:00 EDT 2018
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
Biochemical and biophysical research communications
Du Y,Zhang W,Liu S,Feng X,Gao F,Liu Q
Mon Sep 03 00:00:00 EDT 2018
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Biochemical and biophysical research communications
Guan X,Chen S,Liu Y,Wang LL,Zhao Y,Zong ZH
Mon Feb 26 00:00:00 EST 2018
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Biochemical and biophysical research communications
Guan X,Chen S,Liu Y,Wang LL,Zhao Y,Zong ZH
Mon Feb 26 00:00:00 EST 2018
Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo.
Biochemical and biophysical research communications
Jia C,Kong D,Guo Y,Li L,Quan L
Fri Nov 02 00:00:00 EDT 2018
Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo.
Biochemical and biophysical research communications
Jia C,Kong D,Guo Y,Li L,Quan L
Fri Nov 02 00:00:00 EDT 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Autoimmunity
Tang H,Bai Y,Shen W,Wei Y,Xu M,Zhou X,Zhao J
Fri Jun 01 00:00:00 EDT 2018
Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer.
Autoimmunity
Tang H,Bai Y,Shen W,Wei Y,Xu M,Zhou X,Zhao J
Fri Jun 01 00:00:00 EDT 2018
In Vitro and In Vivo Inhibitory Effect of Gujin Xiaoliu Tang in Non-Small Cell Lung Cancer.
Evidence-based complementary and alternative medicine : eCAM
Hou C,Zhou DH,Wu YJ,Dai XJ,Wang QY,Wu YQ,Zhang EX
Thu Oct 01 00:00:00 EDT 2020
In Vitro and In Vivo Inhibitory Effect of Gujin Xiaoliu Tang in Non-Small Cell Lung Cancer.
Evidence-based complementary and alternative medicine : eCAM
Hou C,Zhou DH,Wu YJ,Dai XJ,Wang QY,Wu YQ,Zhang EX
Thu Oct 01 00:00:00 EDT 2020
STAT3 is required for proliferation and exhibits a cell type-specific binding preference in mouse female germline stem cells.
Molecular omics
Gu Y,Wu J,Yang W,Xia C,Shi X,Li H,Sun J,Shao Z,Wu J,Zhao X
Mon Apr 16 00:00:00 EDT 2018
STAT3 is required for proliferation and exhibits a cell type-specific binding preference in mouse female germline stem cells.
Molecular omics
Gu Y,Wu J,Yang W,Xia C,Shi X,Li H,Sun J,Shao Z,Wu J,Zhao X
Mon Apr 16 00:00:00 EDT 2018
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Cell death & disease
Shen H,Zhan M,Zhang Y,Huang S,Xu S,Huang X,He M,Yao Y,Man M,Wang J
Mon Jan 22 00:00:00 EST 2018
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Cell death & disease
Shen H,Zhan M,Zhang Y,Huang S,Xu S,Huang X,He M,Yao Y,Man M,Wang J
Mon Jan 22 00:00:00 EST 2018
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Medical science monitor : international medical journal of experimental and clinical research
Chen S,Deng G,Li K,Zheng H,Wang G,Yu B,Zhang K
Fri Mar 16 00:00:00 EDT 2018
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Medical science monitor : international medical journal of experimental and clinical research
Chen S,Deng G,Li K,Zheng H,Wang G,Yu B,Zhang K
Fri Mar 16 00:00:00 EDT 2018
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Molecular & cellular proteomics : MCP
Wang W,Hu Y,Yang C,Zhu S,Wang X,Zhang Z,Deng H
Mon Oct 01 00:00:00 EDT 2018
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Molecular & cellular proteomics : MCP
Wang W,Hu Y,Yang C,Zhu S,Wang X,Zhang Z,Deng H
Mon Oct 01 00:00:00 EDT 2018
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Molecular carcinogenesis
Du Y,Wang L,Chen S,Liu Y,Zhao Y
Sat Sep 01 00:00:00 EDT 2018
MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11.
Molecular medicine reports
Yu L,Wang S,Lin X,Lu Y,Gu P
Thu Mar 01 00:00:00 EST 2018
IL-8 Secreted from M2 Macrophages Promoted Prostate Tumorigenesis via STAT3/MALAT1 Pathway.
International journal of molecular sciences
Zheng T,Ma G,Tang M,Li Z,Xu R
Thu Dec 27 00:00:00 EST 2018
IL-8 Secreted from M2 Macrophages Promoted Prostate Tumorigenesis via STAT3/MALAT1 Pathway.
International journal of molecular sciences
Zheng T,Ma G,Tang M,Li Z,Xu R
Thu Dec 27 00:00:00 EST 2018
Anti-Obesity Effect of Chitosan Oligosaccharide Capsules (COSCs) in Obese Rats by Ameliorating Leptin Resistance and Adipogenesis.
Marine drugs
Pan H,Fu C,Huang L,Jiang Y,Deng X,Guo J,Su Z
Tue Jun 05 00:00:00 EDT 2018
Anti-Obesity Effect of Chitosan Oligosaccharide Capsules (COSCs) in Obese Rats by Ameliorating Leptin Resistance and Adipogenesis.
Marine drugs
Pan H,Fu C,Huang L,Jiang Y,Deng X,Guo J,Su Z
Tue Jun 05 00:00:00 EDT 2018
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
Cancer medicine
Yang Y,Cao Y,Chen L,Liu F,Qi Z,Cheng X,Wang Z
Sat Sep 01 00:00:00 EDT 2018
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
Cancer medicine
Yang Y,Cao Y,Chen L,Liu F,Qi Z,Cheng X,Wang Z
Sat Sep 01 00:00:00 EDT 2018
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
RSC advances
Tian Y,He J,Liu N,Huang D,Liu Z,Yang Y,Chen J,Zhao B,Zhao S,Liang B
Wed Jun 13 00:00:00 EDT 2018
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
RSC advances
Tian Y,He J,Liu N,Huang D,Liu Z,Yang Y,Chen J,Zhao B,Zhao S,Liang B
Wed Jun 13 00:00:00 EDT 2018
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Medical science monitor : international medical journal of experimental and clinical research
Gao J,Xiong R,Xiong D,Zhao W,Zhang S,Yin T,Zhang X,Jiang G,Yin Z
Mon Nov 26 00:00:00 EST 2018
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Medical science monitor : international medical journal of experimental and clinical research
Gao J,Xiong R,Xiong D,Zhao W,Zhang S,Yin T,Zhang X,Jiang G,Yin Z
Mon Nov 26 00:00:00 EST 2018
The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yin Y,Yao S,Hu Y,Feng Y,Li M,Bian Z,Zhang J,Qin Y,Qi X,Zhou L,Fei B,Zou J,Hua D,Huang Z
Fri Dec 01 00:00:00 EST 2017
The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yin Y,Yao S,Hu Y,Feng Y,Li M,Bian Z,Zhang J,Qin Y,Qi X,Zhou L,Fei B,Zou J,Hua D,Huang Z
Fri Dec 01 00:00:00 EST 2017
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Cellular signalling
Quan Z,He Y,Luo C,Xia Y,Zhao Y,Liu N,Wu X
Sat Apr 01 00:00:00 EDT 2017
Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.
Cellular signalling
Quan Z,He Y,Luo C,Xia Y,Zhao Y,Liu N,Wu X
Sat Apr 01 00:00:00 EDT 2017
Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.
Cellular signalling
Zhang F,Lu YX,Chen Q,Zou HM,Zhang JM,Hu YH,Li XM,Zhang WJ,Zhang W,Lin C,Li XN
Tue Aug 01 00:00:00 EDT 2017
Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.
Cellular signalling
Zhang F,Lu YX,Chen Q,Zou HM,Zhang JM,Hu YH,Li XM,Zhang WJ,Zhang W,Lin C,Li XN
Tue Aug 01 00:00:00 EDT 2017
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Mediators of inflammation
Liu Q,Du Y,Li K,Zhang W,Feng X,Hao J,Li H,Liu S
Tue Apr 03 00:00:00 EDT 2018
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Mediators of inflammation
Liu Q,Du Y,Li K,Zhang W,Feng X,Hao J,Li H,Liu S
Tue Apr 03 00:00:00 EDT 2018
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Cell biology international
Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z
Fri Dec 01 00:00:00 EST 2017
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Cell biology international
Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z
Fri Dec 01 00:00:00 EST 2017
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells.
Toxicology and applied pharmacology
Wonganan O,He YJ,Shen XF,Wongkrajang K,Suksamrarn A,Zhang GL,Wang F
Fri Dec 01 00:00:00 EST 2017
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells.
Toxicology and applied pharmacology
Wonganan O,He YJ,Shen XF,Wongkrajang K,Suksamrarn A,Zhang GL,Wang F
Fri Dec 01 00:00:00 EST 2017
Lower Serum Levels of miR-29c-3p and miR-19b-3p as Biomarkers for Alzheimer's Disease.
The Tohoku journal of experimental medicine
Wu Y,Xu J,Xu J,Cheng J,Jiao D,Zhou C,Dai Y,Chen Q
Thu Jun 01 00:00:00 EDT 2017
Lower Serum Levels of miR-29c-3p and miR-19b-3p as Biomarkers for Alzheimer's Disease.
The Tohoku journal of experimental medicine
Wu Y,Xu J,Xu J,Cheng J,Jiao D,Zhou C,Dai Y,Chen Q
Thu Jun 01 00:00:00 EDT 2017
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
Oncotarget
Yu X,Zhang F,Mao J,Lu Y,Li J,Ma W,Fan S,Zhang C,Li Q,Wang B,Song B,Li L
Fri Nov 17 00:00:00 EST 2017
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
Oncotarget
Yu X,Zhang F,Mao J,Lu Y,Li J,Ma W,Fan S,Zhang C,Li Q,Wang B,Song B,Li L
Fri Nov 17 00:00:00 EST 2017
Dietary quercetin potentiates the antiproliferative effect of interferon-α in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase.
Oncotarget
Igbe I,Shen XF,Jiao W,Qiang Z,Deng T,Li S,Liu WL,Liu HW,Zhang GL,Wang F
Tue Dec 26 00:00:00 EST 2017
Dietary quercetin potentiates the antiproliferative effect of interferon-α in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase.
Oncotarget
Igbe I,Shen XF,Jiao W,Qiang Z,Deng T,Li S,Liu WL,Liu HW,Zhang GL,Wang F
Tue Dec 26 00:00:00 EST 2017
Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization.
Scientific reports
Chao J,Zhang Y,Du L,Zhou R,Wu X,Shen K,Yao H
Thu Sep 14 00:00:00 EDT 2017
Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization.
Scientific reports
Chao J,Zhang Y,Du L,Zhou R,Wu X,Shen K,Yao H
Thu Sep 14 00:00:00 EDT 2017
Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy.
Oncotarget
Feng T,Cao W,Shen W,Zhang L,Gu X,Guo Y,Tsai HI,Liu X,Li J,Zhang J,Li S,Wu F,Liu Y
Tue Jan 03 00:00:00 EST 2017
Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy.
Oncotarget
Feng T,Cao W,Shen W,Zhang L,Gu X,Guo Y,Tsai HI,Liu X,Li J,Zhang J,Li S,Wu F,Liu Y
Tue Jan 03 00:00:00 EST 2017
Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression.
Cell & bioscience
Xiong Q,Wu S,Wang J,Zeng X,Chen J,Wei M,Guan H,Fan C,Chen L,Guo D,Sun G
Wed Sep 30 00:00:00 EDT 2020
Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression.
Cell & bioscience
Xiong Q,Wu S,Wang J,Zeng X,Chen J,Wei M,Guan H,Fan C,Chen L,Guo D,Sun G
Wed Sep 30 00:00:00 EDT 2020
Overlapping Mechanisms of Peripheral Nerve Regeneration and Angiogenesis Following Sciatic Nerve Transection.
Frontiers in cellular neuroscience
Wang H,Zhu H,Guo Q,Qian T,Zhang P,Li S,Xue C,Gu X
Fri Mar 18 00:00:00 EDT 2022
Overlapping Mechanisms of Peripheral Nerve Regeneration and Angiogenesis Following Sciatic Nerve Transection.
Frontiers in cellular neuroscience
Wang H,Zhu H,Guo Q,Qian T,Zhang P,Li S,Xue C,Gu X
Fri Mar 18 00:00:00 EDT 2022
Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Scientific reports
Dai M,Zhu XL,Liu F,Xu QY,Ge QL,Jiang SH,Yang XM,Li J,Wang YH,Wu QK,Ai ZH,Teng YC,Zhang ZG
Mon Jan 23 00:00:00 EST 2017
Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Scientific reports
Dai M,Zhu XL,Liu F,Xu QY,Ge QL,Jiang SH,Yang XM,Li J,Wang YH,Wu QK,Ai ZH,Teng YC,Zhang ZG
Mon Jan 23 00:00:00 EST 2017
STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4.
Molecular cancer
Wang H,Huo X,Yang XR,He J,Cheng L,Wang N,Deng X,Jin H,Wang N,Wang C,Zhao F,Fang J,Yao M,Fan J,Qin W
Mon Aug 14 00:00:00 EDT 2017
STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4.
Molecular cancer
Wang H,Huo X,Yang XR,He J,Cheng L,Wang N,Deng X,Jin H,Wang N,Wang C,Zhao F,Fang J,Yao M,Fan J,Qin W
Mon Aug 14 00:00:00 EDT 2017
STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4.
Molecular cancer
Wang H,Huo X,Yang XR,He J,Cheng L,Wang N,Deng X,Jin H,Wang N,Wang C,Zhao F,Fang J,Yao M,Fan J,Qin W
Mon Aug 14 00:00:00 EDT 2017
STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4.
Molecular cancer
Wang H,Huo X,Yang XR,He J,Cheng L,Wang N,Deng X,Jin H,Wang N,Wang C,Zhao F,Fang J,Yao M,Fan J,Qin W
Mon Aug 14 00:00:00 EDT 2017
IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.
American journal of physiology. Renal physiology
Xiao J,Gong Y,Chen Y,Yu D,Wang X,Zhang X,Dou Y,Liu D,Cheng G,Lu S,Yuan W,Li Y,Zhao Z
Tue Aug 01 00:00:00 EDT 2017
IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.
American journal of physiology. Renal physiology
Xiao J,Gong Y,Chen Y,Yu D,Wang X,Zhang X,Dou Y,Liu D,Cheng G,Lu S,Yuan W,Li Y,Zhao Z
Tue Aug 01 00:00:00 EDT 2017
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
International journal of oncology
Hu K,Tian Y,Du Y,Huang L,Chen J,Li N,Liu W,Liang Z,Zhao L
Sun May 01 00:00:00 EDT 2016
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
International journal of oncology
Hu K,Tian Y,Du Y,Huang L,Chen J,Li N,Liu W,Liang Z,Zhao L
Sun May 01 00:00:00 EDT 2016
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
Toxicology letters
Guan R,Zhao X,Wang X,Song N,Guo Y,Yan X,Jiang L,Cheng W,Shen L
Wed Nov 16 00:00:00 EST 2016
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
Toxicology letters
Guan R,Zhao X,Wang X,Song N,Guo Y,Yan X,Jiang L,Cheng W,Shen L
Wed Nov 16 00:00:00 EST 2016
Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling.
Biochemical and biophysical research communications
Yan H,Guo BY,Zhang S
Fri Feb 19 00:00:00 EST 2016
Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling.
Biochemical and biophysical research communications
Yan H,Guo BY,Zhang S
Fri Feb 19 00:00:00 EST 2016
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Oncotarget
Cao N,Ma X,Guo Z,Zheng Y,Geng S,Meng M,Du Z,Lin H,Duan Y,Du G
Tue Sep 20 00:00:00 EDT 2016
Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling.
Oncotarget
Xu BQ,Fu ZG,Meng Y,Wu XQ,Wu B,Xu L,Jiang JL,Li L,Chen ZN
Tue Sep 20 00:00:00 EDT 2016
Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling.
Oncotarget
Xu BQ,Fu ZG,Meng Y,Wu XQ,Wu B,Xu L,Jiang JL,Li L,Chen ZN
Tue Sep 20 00:00:00 EDT 2016
Paper-based microreactor array for rapid screening of cell signaling cascades.
Lab on a chip
Huang CH,Lei KF,Tsang NM
Sun Aug 07 00:00:00 EDT 2016
Paper-based microreactor array for rapid screening of cell signaling cascades.
Lab on a chip
Huang CH,Lei KF,Tsang NM
Sun Aug 07 00:00:00 EDT 2016
Gx-50 Inhibits Neuroinflammation via α7 nAChR Activation of the JAK2/STAT3 and PI3K/AKT Pathways.
Journal of Alzheimer's disease : JAD
Shi S,Liang D,Bao M,Xie Y,Xu W,Wang L,Wang Z,Qiao Z
Mon Oct 31 00:00:00 EDT 2016
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1.
IUBMB life
Xing WJ,Liao XH,Wang N,Zhao DW,Zheng L,Zheng DL,Dong J,Zhang TC
Sun Mar 01 00:00:00 EST 2015
MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1.
IUBMB life
Xing WJ,Liao XH,Wang N,Zhao DW,Zheng L,Zheng DL,Dong J,Zhang TC
Sun Mar 01 00:00:00 EST 2015
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
BMC pulmonary medicine
Dong Z,Lu X,Yang Y,Zhang T,Li Y,Chai Y,Lei W,Li C,Ai L,Tai W
Wed Feb 18 00:00:00 EST 2015
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
BMC pulmonary medicine
Dong Z,Lu X,Yang Y,Zhang T,Li Y,Chai Y,Lei W,Li C,Ai L,Tai W
Wed Feb 18 00:00:00 EST 2015
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Cellular signalling
Cai Y,Chen H,Mo X,Tang Y,Xu X,Zhang A,Lun Z,Lu F,Wang Y,Shen J
Sun Jun 01 00:00:00 EDT 2014
Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17-92-Bim pathway in macrophages.
Cellular signalling
Cai Y,Chen H,Mo X,Tang Y,Xu X,Zhang A,Lun Z,Lu F,Wang Y,Shen J
Sun Jun 01 00:00:00 EDT 2014
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
Parasites & vectors
Cai Y,Chen H,Jin L,You Y,Shen J
Mon Dec 16 00:00:00 EST 2013
STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage.
Parasites & vectors
Cai Y,Chen H,Jin L,You Y,Shen J
Mon Dec 16 00:00:00 EST 2013
A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells.
Journal of cellular and molecular medicine
Rathinavelu A,Narasimhan M,Muthumani P
Wed Aug 01 00:00:00 EDT 2012
A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells.
Journal of cellular and molecular medicine
Rathinavelu A,Narasimhan M,Muthumani P
Wed Aug 01 00:00:00 EDT 2012
Cholesteatoma growth and proliferation: relevance with serpin B3.
The Laryngoscope
Ho KY,Huang HH,Hung KF,Chen JC,Chai CY,Chen WT,Tsai SM,Chien CY,Wang HM,Wu YJ
Sat Dec 01 00:00:00 EST 2012
Cholesteatoma growth and proliferation: relevance with serpin B3.
The Laryngoscope
Ho KY,Huang HH,Hung KF,Chen JC,Chai CY,Chen WT,Tsai SM,Chien CY,Wang HM,Wu YJ
Sat Dec 01 00:00:00 EST 2012
