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TOM20 Polyclonal Antibody

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Antibody Testing Data (14)

TOM20 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

TOM20 Antibody (11802-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HUVEC cells using TOM20 antibody (Product # 11802-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red).

TOM20 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

TOM20 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11802-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:8,000

View 232 publications 232 publications

Immunohistochemistry (IHC)

View 16 publications 16 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 178 publications 178 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 4 publications 4 publications

Not applicable (N/A)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TOM20 Fusion Protein Ag2378 (1-145 aa encoded by BC000882)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MVGRNSAIA AGVCGALFIG YCIYFDRKRR SDPNFKNRLR ERRKKQKLAK ERAGLSKLPD LKDAEAVQKF FLEEIQLGEE LLAQGEYEKG VDHLTNAIAV CGQPQQLLQV LQQTLPPPVF QMLLTKLPTI SQRIVSAQSL AEDDVE (1-145 aa encoded by B C000882)

Target Information

The mitochondrial preprotein translocases of the outer membrane (Tom) is a multisubunit protein complex that facilitates the import of nucleus-encoded precursor proteins across the mitochondrial outer membrane. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria. The import receptors include Tom20 and Tom22, which form a heteromeric receptor complex that initiates the insertion of newly synthesized proteins into the outer membrane and then directs the precursor protein into the GIP. In yeast, Tom22 is the essential component of the import receptor complex as it functions as both a receptor for the preproteins and serves as a docking point for both Tom20 and the GIP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Substitution of PINK1 Gly411 modulates substrate receptivity and turnover.

Autophagy

Fiesel FC,Fričová D,Hayes CS,Coban MA,Hudec R,Bredenberg JM,Broadway BJ,Markham BN,Yan T,Boneski PK,Fiorino G,Watzlawik JO,Hou X,McCarty AM,Lewis-Tuffin LJ,Zhong J,Madden BJ,Ordureau A,An H,Puschmann A,Wszolek ZK,Ross OA,Harper JW,Caulfield TR,Springer W

Thu Jun 01 00:00:00 EDT 2023

Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, and mitochondrial dysfunction in adipose tissue.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Qiu R,Wang S,Lin D,He Y,Huang S,Wu B,Li H,Wang M,Zheng F

Wed Feb 01 00:00:00 EST 2023

NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.

International immunopharmacology

Jiang Y,Li Y,Zhang Y,Hu D,Zhang S,Wang C,Huang S,Zhang A,Jia Z,You R

Wed Mar 01 00:00:00 EST 2023

Effect of mitophagy in the formation of osteomorphs derived from osteoclasts.

iScience

Huang T,Wang Y,Yu Z,Miao X,Jiang Z,Yu K,Fu M,Lai K,Wang Y,Yang G

Fri May 19 00:00:00 EDT 2023

Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand.

eLife

Greiser M,Karbowski M,Kaplan AD,Coleman AK,Verhoeven N,Mannella CA,Lederer WJ,Boyman L

Mon Jun 05 00:00:00 EDT 2023

Glut10 restrains neointima formation by promoting SMCs mtDNA demethylation and improving mitochondrial function.

Translational research : the journal of laboratory and clinical medicine

Wu Q,Hu Z,Wang Z,Che Y,Zhang M,Zheng S,Xing K,Zhong X,Chen Y,Shi F,Yuan S

Sun Oct 01 00:00:00 EDT 2023

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart.

bioRxiv : the preprint server for biology

Ohanele C,Peoples JN,Karlstaedt A,Geiger JT,Gayle AD,Ghazal N,Sohani F,Brown ME,Davis ME,Porter GA,Faundez V,Kwong JQ

Mon May 22 00:00:00 EDT 2023

Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex.

Signal transduction and targeted therapy

Cai S,Zhang C,Zhuang Z,Zhang S,Ma L,Yang S,Zhou T,Wang Z,Xie W,Jin S,Zhao J,Guan X,Wu J,Cui J,Wu Y

Wed Apr 26 00:00:00 EDT 2023

Plasma membrane lipid composition and metabolomics analysis of Yorkshire boar sperms with high and low resistance to cryopreservation.

Theriogenology

Zhang Y,Yuan W,Liu Y,Liu Y,Liang H,Xu Q,Liu Z,Weng X

Tue Aug 01 00:00:00 EDT 2023

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.

Nature metabolism

Green AC,Marttila P,Kiweler N,Chalkiadaki C,Wiita E,Cookson V,Lesur A,Eiden K,Bernardin F,Vallin KSA,Borhade S,Long M,Ghahe EK,Jiménez-Alonso JJ,Jemth AS,Loseva O,Mortusewicz O,Meyers M,Viry E,Johansson AI,Hodek O,Homan E,Bonagas N,Ramos L,Sandberg L,Frödin M,Moussay E,Slipicevic A,Letellier E,Paggetti J,Sørensen CS,Helleday T,Henriksson M,Meiser J

Sat Apr 01 00:00:00 EDT 2023

Oxidative stress in human gingival fibroblasts from periodontitis versus healthy counterparts.

Oral diseases

Liu J,Wang X,Zheng M,Luan Q

Sat Apr 01 00:00:00 EDT 2023

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.

Nature communications

Chen Z,Ho IL,Soeung M,Yen EY,Liu J,Yan L,Rose JL,Srinivasan S,Jiang S,Edward Chang Q,Feng N,Gay JP,Wang Q,Wang J,Lorenzi PL,Veillon LJ,Wei B,Weinstein JN,Deem AK,Gao S,Genovese G,Viale A,Yao W,Lyssiotis CA,Marszalek JR,Draetta GF,Ying H

Mon Apr 17 00:00:00 EDT 2023

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.

Nature communications

Mon Apr 17 00:00:00 EDT 2023

Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice.

Cell biology and toxicology

Wang X,Wang L,Luo M,Bu Q,Liu C,Jiang L,Xu R,Wang S,Zhang H,Zhang J,Wan X,Li H,Wang Y,Liu B,Zhao Y,Chen Y,Dai Y,Li M,Wang H,Tian J,Zhao Y,Cen X

Thu Jun 01 00:00:00 EDT 2023

FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.

Autophagy

Cai W,Hu M,Li C,Wu R,Lu D,Xie C,Zhang W,Li T,Shen S,Huang H,Qiu W,Liu Q,Lu Y,Lu Z

Sat Apr 01 00:00:00 EDT 2023

SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.

Cell reports

Jiang X,Liu K,Jiang H,Yin H,Wang ED,Cheng H,Yuan F,Xiao F,Wang F,Lu W,Peng B,Shu Y,Li X,Chen S,Guo F

Tue Jan 31 00:00:00 EST 2023

SAR-guided development of indole-matrine hybrids as potential anticancer agents via mitochondrial stress/cytochrome c/caspase 3 signaling pathway.

Bioorganic chemistry

Li L,Li J,Ma L,Shang H,Zou Z

Mon May 01 00:00:00 EDT 2023

High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.

International immunopharmacology

Dong Y,Han F,Su Y,Sun B,Zhao W,Pan C

Mon May 01 00:00:00 EDT 2023

High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.

International immunopharmacology

Dong Y,Han F,Su Y,Sun B,Zhao W,Pan C

Mon May 01 00:00:00 EDT 2023

Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.

The FEBS journal

Wei Y,Xiao G,Xu H,Sun X,Shi Y,Wang F,Kang J,Peng J,Zhou F

Sat Jul 01 00:00:00 EDT 2023

Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.

The FEBS journal

Wei Y,Xiao G,Xu H,Sun X,Shi Y,Wang F,Kang J,Peng J,Zhou F

Sat Jul 01 00:00:00 EDT 2023

L-OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice.

Journal of cellular physiology

Jiang HL,Yang HH,Liu YB,Zhang CY,Zhong WJ,Guan XX,Jin L,Hong JR,Yang JT,Tan XH,Li Q,Zhou Y,Guan CX

Fri Jul 01 00:00:00 EDT 2022

Examining Mitochondrial Morphology in Mouse Brains.

Methods in molecular biology (Clifton, N.J.)

Royea J,Khacho M

Thu Jul 07 00:00:00 EDT 2022

Examining Mitochondrial Morphology in Mouse Brains.

Methods in molecular biology (Clifton, N.J.)

Royea J,Khacho M

Thu Jul 07 00:00:00 EDT 2022

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.

iScience

Ryan DG,Knatko EV,Casey AM,Hukelmann JL,Dayalan Naidu S,Brenes AJ,Ekkunagul T,Baker C,Higgins M,Tronci L,Nikitopolou E,Honda T,Hartley RC,O'Neill LAJ,Frezza C,Lamond AI,Abramov AY,Arthur JSC,Cantrell DA,Murphy MP,Dinkova-Kostova AT

Fri Feb 18 00:00:00 EST 2022

Knockdown of mitochondrial threonyl-tRNA synthetase 2 inhibits lung adenocarcinoma cell proliferation and induces apoptosis.

Bioengineered

Tian H,Yan H,Zhang Y,Fu Q,Li C,He J,Li H,Zhou Y,Huang Y,Li R

Tue Mar 01 00:00:00 EST 2022

Prohibitin 1 regulates mtDNA release and downstream inflammatory responses.

The EMBO journal

Liu H,Fan H,He P,Zhuang H,Liu X,Chen M,Zhong W,Zhang Y,Zhen C,Li Y,Jiang H,Meng T,Xu Y,Zhao G,Feng D

Thu Dec 15 00:00:00 EST 2022

Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver.

iScience

Yamada T,Murata D,Kleiner DE,Anders R,Rosenberg AZ,Kaplan J,Hamilton JP,Aghajan M,Levi M,Wang NY,Dawson TM,Yanagawa T,Powers AF,Iijima M,Sesaki H

Fri Apr 15 00:00:00 EDT 2022

Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Han X,Hu S,Yang Q,Sang X,Tang D,Cao G

Tue Feb 01 00:00:00 EST 2022

Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro.

Frontiers in cardiovascular medicine

Heuschkel MA,Babler A,Heyn J,van der Vorst EPC,Steenman M,Gesper M,Kappel BA,Magne D,Gouëffic Y,Kramann R,Jahnen-Dechent W,Marx N,Quillard T,Goettsch C

Sun Oct 09 00:00:00 EDT 2022

Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.

Neuropharmacology

Qiu J,Chen Y,Zhuo J,Zhang L,Liu J,Wang B,Sun D,Yu S,Lou H

Fri Apr 01 00:00:00 EDT 2022

Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.

Frontiers in pharmacology

Zhu Z,Wang X,Song Z,Zuo X,Ma Y,Zhang Z,Ju C,Liang Z,Li K,Hu X,Wang Z

Fri Sep 30 00:00:00 EDT 2022

Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.

Acta histochemica

Wu H,Li G,Chen W,Luo W,Yang Z,You Z,Zou Y

Sat Jan 01 00:00:00 EST 2022

Manganese-Induced Oxidative Stress Contributes to Intestinal Lipid Deposition via the Deacetylation of PPARγ at K339 by SIRT1.

Antioxidants & redox signaling

Lv WH,Zhao T,Pantopoulos K,Chen GH,Wei XL,Zhang DG,Luo Z

Thu Sep 01 00:00:00 EDT 2022

Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.

Frontiers in aging neuroscience

Cao X,Chen Y,Sang X,Xu S,Xie Z,Zhu Z,Wang P,Bi J,Xu L

Tue Nov 22 00:00:00 EST 2022

Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Jin Z,Chang B,Wei Y,Yang Y,Zhang H,Liu J,Piao L,Bai L

Fri Jul 01 00:00:00 EDT 2022

Activation of UCP2 by anethole trithione suppresses neuroinflammation after intracerebral hemorrhage.

Acta pharmacologica Sinica

Yan XL,Xu FY,Ji JJ,Song P,Pei YQ,He MJ,Wang ZC,You SJ,Hua ZC,Cheng J,Jia J

Fri Apr 01 00:00:00 EDT 2022

Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses.

Investigative ophthalmology & visual science

Li J,Tan X,Sun Q,Li X,Chen R,Luo L

Thu Sep 01 00:00:00 EDT 2022

Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.

Cell death & disease

Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G

Thu Oct 06 00:00:00 EDT 2022

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.

Journal of experimental & clinical cancer research : CR

Lin F,Li X,Wang X,Sun H,Wang Z,Wang X

Thu Apr 07 00:00:00 EDT 2022

Increased Mobile Zinc Regulates Retinal Ganglion Cell Survival via Activating Mitochondrial OMA1 and Integrated Stress Response.

Antioxidants (Basel, Switzerland)

Tang J,Liu Z,Han J,Xue J,Liu L,Lin J,Wu C,Zhang Q,Wu S,Liu C,Huang H,Fu Y,Li M,Zhuo Y,Li Y

Mon Oct 10 00:00:00 EDT 2022

TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.

Neuroscience

Huang R,Gao Y,Chen J,Duan Q,He P,Zhang J,Huang H,Zhang Q,Ma G,Zhang Y,Nie K,Wang L

Tue May 10 00:00:00 EDT 2022

In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.

Science advances

Pachnis P,Wu Z,Faubert B,Tasdogan A,Gu W,Shelton S,Solmonson A,Rao AD,Kaushik AK,Rogers TJ,Ubellacker JM,LaVigne CA,Yang C,Ko B,Ramesh V,Sudderth J,Zacharias LG,Martin-Sandoval MS,Do D,Mathews TP,Zhao Z,Mishra P,Morrison SJ,DeBerardinis RJ

Fri Sep 02 00:00:00 EDT 2022

Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.

Oncogene

Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S

Wed Jun 01 00:00:00 EDT 2022

Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.

Oncogene

Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S

Wed Jun 01 00:00:00 EDT 2022

Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.

Molecular cell

Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q

Thu May 19 00:00:00 EDT 2022

Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.

Molecular cell

Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q

Thu May 19 00:00:00 EDT 2022

MIEAP and ATG5 are tumor suppressors in a mouse model of BRAF^V600E-positive thyroid cancer.

Frontiers in endocrinology

Hamada K,Kurashige T,Shimamura M,Arakawa H,Nakamura Y,Nagayama Y

Thu Aug 24 00:00:00 EDT 2023

SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells.

Molecular metabolism

Jackson J,Wischhof L,Scifo E,Pellizzer A,Wang Y,Piazzesi A,Gentile D,Siddig S,Stork M,Hopkins CE,Händler K,Weis J,Roos A,Schultze JL,Nicotera P,Ehninger D,Bano D

Fri Jul 01 00:00:00 EDT 2022

Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation.

International journal of biological sciences

Ni Y,Wu GH,Cai JJ,Zhang R,Zheng Y,Liu JQ,Yang XH,Yang X,Shen Y,Lai JM,Ye XM,Mo SJ

Mon Aug 22 00:00:00 EDT 2022

Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.

Journal of hazardous materials

Kang Y,Yin S,Liu J,Jiang Y,Huang Z,Chen L,Shao L

Tue Feb 15 00:00:00 EST 2022

The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.

Frontiers in molecular neuroscience

Zhong F,Gan Y,Song J,Zhang W,Yuan S,Qin Z,Wu J,Lü Y,Yu W

Wed Jan 11 00:00:00 EST 2023

Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.

International journal of molecular sciences

Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J,Zou Y

Thu Apr 28 00:00:00 EDT 2022

Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.

Food & function

Liu J,Jiang J,Qiu J,Wang L,Zhuo J,Wang B,Sun D,Yu S,Lou H

Tue Jan 04 00:00:00 EST 2022

Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology.

Cellular and molecular life sciences : CMLS

Lurette O,Guedouari H,Morris JL,Martín-Jiménez R,Robichaud JP,Hamel-Côté G,Khan M,Dauphinee N,Pichaud N,Prudent J,Hebert-Chatelain E

Mon May 30 00:00:00 EDT 2022

Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke.

Oxidative medicine and cellular longevity

Sun E,Zhang J,Deng Y,Wang J,Wu Q,Chen W,Ma X,Chen S,Xiang X,Chen Y,Wu T,Yang Y,Chen B

Wed Oct 19 00:00:00 EDT 2022

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.

The EMBO journal

Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L

Thu Dec 01 00:00:00 EST 2022

PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.

Frontiers in cell and developmental biology

Li C,Pan Y,Tan Y,Wang Y,Sun X

Tue Jul 26 00:00:00 EDT 2022

PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.

Frontiers in cell and developmental biology

Li C,Pan Y,Tan Y,Wang Y,Sun X

Tue Jul 26 00:00:00 EDT 2022

Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.

BMC pulmonary medicine

Li MY,Qin YQ,Tian YG,Li KC,Oliver BG,Liu XF,Zhao P,Li JS

Tue Nov 22 00:00:00 EST 2022

Short-form OPA1 is a molecular chaperone in mitochondrial intermembrane space.

Science China. Life sciences

Yao D,Li Y,Zeng S,Li Z,Shah Z,Song B,Liu J,Wu Y,Yang L,Long Q,Wang W,Hu Z,Tang H,Liu X

Tue Feb 01 00:00:00 EST 2022

CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma.

Autophagy

Yao J,Wang J,Xu Y,Guo Q,Sun Y,Liu J,Li S,Guo Y,Wei L

Mon Aug 01 00:00:00 EDT 2022

Autophagy

Yao J,Wang J,Xu Y,Guo Q,Sun Y,Liu J,Li S,Guo Y,Wei L

Mon Aug 01 00:00:00 EDT 2022

BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.

The EMBO journal

Wischhof L,Lee HM,Tutas J,Overkott C,Tedt E,Stork M,Peitz M,Brüstle O,Ulas T,Händler K,Schultze JL,Ehninger D,Nicotera P,Salomoni P,Bano D

Thu Dec 01 00:00:00 EST 2022

Obstructive Sleep Apnea Affects Lacrimal Gland Function.

Investigative ophthalmology & visual science

Wang S,He X,Li Q,Zhang Y,Hu J,Zong R,Zhuang J,Quantock AJ,Gao Y,Li W,Liu Z

Wed Mar 02 00:00:00 EST 2022

Loss of legumain induces premature senescence and mediates aging-related renal fibrosis.

Aging cell

Wang D,Kang L,Chen C,Guo J,Du L,Zhou D,Li G,Zhang Y,Mi X,Zhang M,Liu S,Tan X

Tue Mar 01 00:00:00 EST 2022

San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.

Journal of diabetes research

Li H,Wang Y,Su X,Wang Q,Zhang S,Sun W,Zhang T,Dong M,Zhang Z,Lv S

Mon Nov 28 00:00:00 EST 2022

Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.

Journal of reproductive immunology

Zhu Q,Muyayalo KP,Xu QH,Wang J,Wang H,Liao AH

Tue Feb 01 00:00:00 EST 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 EDT 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 EDT 2022

Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases.

Nature communications

Watanabe S,Nihongaki Y,Itoh K,Uyama T,Toda S,Watanabe S,Inoue T

Fri Jul 29 00:00:00 EDT 2022

Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.

Autophagy

Song Y,Ge X,Chen Y,Hussain T,Liang Z,Dong Y,Wang Y,Tang C,Zhou X

Wed Jun 01 00:00:00 EDT 2022

MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis.

Nature communications

Takahashi H,Yang G,Yoneshiro T,Abe Y,Ito R,Yang C,Nakazono J,Okamoto-Katsuyama M,Uchida A,Arai M,Jin H,Choi H,Tumenjargal M,Xie S,Zhang J,Sagae H,Zhao Y,Yamaguchi R,Nomura Y,Shimizu Y,Yamada K,Yasuda S,Kimura H,Tanaka T,Wada Y,Kodama T,Aburatani H,Zhu MS,Inagaki T,Osborne TF,Kawamura T,Ishihama Y,Matsumura Y,Sakai J

Thu Sep 29 00:00:00 EDT 2022

Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia.

Journal of cachexia, sarcopenia and muscle

Ito A,Hashimoto M,Tanihata J,Matsubayashi S,Sasaki R,Fujimoto S,Kawamoto H,Hosaka Y,Ichikawa A,Kadota T,Fujita Y,Takekoshi D,Ito S,Minagawa S,Numata T,Hara H,Matsuoka T,Udaka J,Araya J,Saito M,Kuwano K

Wed Jun 01 00:00:00 EDT 2022

Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy.

Proceedings of the National Academy of Sciences of the United States of America

Ta N,Qu C,Wu H,Zhang D,Sun T,Li Y,Wang J,Wang X,Tang T,Chen Q,Liu L

Tue Sep 06 00:00:00 EDT 2022

Maternal exposure to CeO₂NPs derails placental development through trophoblast dysfunction mediated by excessive autophagy activation.

Journal of nanobiotechnology

Chen Z,Geng Y,Gao R,Zhong H,Chen J,Mu X,Chen X,Zhang Y,Li F,He J

Tue Mar 15 00:00:00 EDT 2022

Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.

Brain research bulletin

Guo L,Jiang ZM,Sun RX,Pang W,Zhou X,Du ML,Chen MX,Lv X,Wang JT

Sun May 01 00:00:00 EDT 2022

Inhibition of the PINK1-Parkin Pathway Enhances the Lethality of Sorafenib and Regorafenib in Hepatocellular Carcinoma.

Frontiers in pharmacology

Zhang S,Wang Y,Cao Y,Wu J,Zhang Z,Ren H,Xu X,Kaznacheyeva E,Li Q,Wang G

Tue Apr 05 00:00:00 EDT 2022

Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.

Neurobiology of disease

Lampinen R,Belaya I,Saveleva L,Liddell JR,Rait D,Huuskonen MT,Giniatullina R,Sorvari A,Soppela L,Mikhailov N,Boccuni I,Giniatullin R,Cruz-Haces M,Konovalova J,Koskuvi M,Domanskyi A,Hämäläinen RH,Goldsteins G,Koistinaho J,Malm T,Chew S,Rilla K,White AR,Marsh-Armstrong N,Kanninen KM

Mon Aug 01 00:00:00 EDT 2022

Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.

Neurobiology of disease

Mon Aug 01 00:00:00 EDT 2022

GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.

Cells

Zhang B,Chen Y,Bao L,Luo W

Sat Aug 20 00:00:00 EDT 2022

Disruption of cellular iron homeostasis by IREB2 missense variants causes severe neurodevelopmental delay, dystonia and seizures.

Brain communications

Maio N,Saneto RP,Steet R,Sotero de Menezes MA,Skinner C,Rouault TA

Sat Sep 16 00:00:00 EDT 2023

Deficient mitochondrial respiration in astrocytes impairs trace fear conditioning and increases naloxone-precipitated aversion in morphine-dependent mice.

Glia

Murlanova K,Jouroukhin Y,Huseynov S,Pletnikova O,Morales MJ,Guan Y,Baraban JM,Bergles DE,Pletnikov MV

Fri Jul 01 00:00:00 EDT 2022

Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A.

Journal of molecular neuroscience : MN

Carsana EV,Lunghi G,Prioni S,Mauri L,Loberto N,Prinetti A,Zucca FA,Bassi R,Sonnino S,Chiricozzi E,Duga S,Straniero L,Asselta R,Soldà G,Samarani M,Aureli M

Fri Jul 01 00:00:00 EDT 2022

Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.

Cell reports

Liang C,Zhang S,Robinson D,Ploeg MV,Wilson R,Nah J,Taylor D,Beh S,Lim R,Sun L,Muoio DM,Stroud DA,Ho L

Tue Aug 16 00:00:00 EDT 2022

Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis.

Journal of periodontal research

Liu J,Wang X,Xue F,Zheng M,Luan Q

Sat Jan 01 00:00:00 EST 2022

MITOL regulates phosphatidic acid-binding activity of RMDN3/PTPIP51.

Journal of biochemistry

Ito N,Takahashi T,Shiiba I,Nagashima S,Inatome R,Yanagi S

Wed May 11 00:00:00 EDT 2022

Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.

Placenta

Li J,Wang Y,Wu T,Li S,Sun YN,Liu ZH

Fri Apr 01 00:00:00 EDT 2022

Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.

GeroScience

Yang L,Wu C,Li Y,Dong Y,Wu CY,Lee RH,Brann DW,Lin HW,Zhang Q

Wed Jun 01 00:00:00 EDT 2022

Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles.

European journal of cell biology

Ramirez A,Old W,Selwood DL,Liu X

Sat Jan 01 00:00:00 EST 2022

Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.

Theranostics

Yang L,Wu C,Parker E,Li Y,Dong Y,Tucker L,Brann DW,Lin HW,Zhang Q

Thu Apr 21 00:00:00 EDT 2022

Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.

Nature communications

Sen A,Kallabis S,Gaedke F,Jüngst C,Boix J,Nüchel J,Maliphol K,Hofmann J,Schauss AC,Krüger M,Wiesner RJ,Pla-Martín D

Mon Nov 07 00:00:00 EST 2022

Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.

Nature communications

Sen A,Kallabis S,Gaedke F,Jüngst C,Boix J,Nüchel J,Maliphol K,Hofmann J,Schauss AC,Krüger M,Wiesner RJ,Pla-Martín D

Mon Nov 07 00:00:00 EST 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 EDT 2022

Scinderin promotes fusion of electron transport chain dysfunctional muscle stem cells with myofibers.

Nature aging

Wang X,Shelton SD,Bordieanu B,Frank AR,Yi Y,Venigalla SSK,Gu Z,Lenser NP,Glogauer M,Chandel NS,Zhao H,Zhao Z,McFadden DG,Mishra P

Tue Jul 18 00:00:00 EDT 2023

Sunitinib and Pterostilbene Combination Treatment Exerts Antitumor Effects in Gastric Cancer via Suppression of PDZD8.

International journal of molecular sciences

Hojo Y,Kishi S,Mori S,Fujiwara-Tani R,Sasaki T,Fujii K,Nishiguchi Y,Nakashima C,Luo Y,Shinohara H,Kuniyasu H

Mon Apr 04 00:00:00 EDT 2022

Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.

Veterinary microbiology

Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J

Tue Mar 01 00:00:00 EST 2022

Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.

Frontiers in cardiovascular medicine

Wei X,Chang ACH,Chang H,Xu S,Xue Y,Zhang Y,Lei M,Chang ACY,Zhang Q

Tue Apr 05 00:00:00 EDT 2022

SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.

European journal of pharmacology

Gao A,Zou J,Mao Z,Zhou H,Zeng G

Sun Jun 05 00:00:00 EDT 2022

The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells.

Cell stem cell

Baker N,Wade S,Triolo M,Girgis J,Chwastek D,Larrigan S,Feige P,Fujita R,Crist C,Rudnicki MA,Burelle Y,Khacho M

Thu Sep 01 00:00:00 EDT 2022

African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.

Viruses

Wang Q,Zhou L,Wang J,Su D,Li D,Du Y,Yang G,Zhang G,Chu B

Tue Feb 15 00:00:00 EST 2022

Systematic Functional Analysis of PINK1 and PRKN Coding Variants.

Cells

Broadway BJ,Boneski PK,Bredenberg JM,Kolicheski A,Hou X,Soto-Beasley AI,Ross OA,Springer W,Fiesel FC

Fri Aug 05 00:00:00 EDT 2022

Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice.

American journal of human genetics

Tan C,Meng L,Lv M,He X,Sha Y,Tang D,Tan Y,Hu T,He W,Tu C,Nie H,Zhang H,Du J,Lu G,Fan LQ,Cao Y,Lin G,Tan YQ

Thu Jan 06 00:00:00 EST 2022

Hyperglycemia Induces Meibomian Gland Dysfunction.

Investigative ophthalmology & visual science

Guo Y,Zhang H,Zhao Z,Luo X,Zhang M,Bu J,Liang M,Wu H,Yu J,He H,Zong R,Chen Y,Liu Z,Li W

Mon Jan 03 00:00:00 EST 2022

Hyperglycemia Induces Meibomian Gland Dysfunction.

Investigative ophthalmology & visual science

Guo Y,Zhang H,Zhao Z,Luo X,Zhang M,Bu J,Liang M,Wu H,Yu J,He H,Zong R,Chen Y,Liu Z,Li W

Mon Jan 03 00:00:00 EST 2022

SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells.

International journal of molecular sciences

Fang X,Xia W,Li S,Qi Y,Liu M,Yu Y,Li H,Li M,Tao C,Wang Z,Li J

Sat Apr 30 00:00:00 EDT 2022

Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction.

ACS chemical neuroscience

Morsy A,Maddeboina K,Gao J,Wang H,Valdez J,Dow LF,Wang X,Trippier PC

Wed Jul 20 00:00:00 EDT 2022

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

International journal of molecular sciences

Dahlke E,Engmann T,Anan Y,Häsler R,Solinas G,Theilig F

Mon Sep 05 00:00:00 EDT 2022

Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40.

Developmental and comparative immunology

Zhu M,Pan J,Zhang M,Tong X,Zhang Y,Zhang Z,Liang Z,Zhang X,Hu X,Xue R,Cao G,Gong C

Sat Jan 01 00:00:00 EST 2022

The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.

Cell death & disease

Li Q,Chu Y,Li S,Yu L,Deng H,Liao C,Liao X,Yang C,Qi M,Cheng J,Chen G,Huang L

Wed Oct 26 00:00:00 EDT 2022

Disruption of STIM1-mediated Ca²⁺ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.

Molecular metabolism

Wilson RJ,Lyons SP,Koves TR,Bryson VG,Zhang H,Li T,Crown SB,Ding JD,Grimsrud PA,Rosenberg PB,Muoio DM

Tue Mar 01 00:00:00 EST 2022

Disruption of STIM1-mediated Ca²⁺ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.

Molecular metabolism

Wilson RJ,Lyons SP,Koves TR,Bryson VG,Zhang H,Li T,Crown SB,Ding JD,Grimsrud PA,Rosenberg PB,Muoio DM

Tue Mar 01 00:00:00 EST 2022

Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.

Redox biology

Li W,Luo LX,Zhou QQ,Gong HB,Fu YY,Yan CY,Li E,Sun J,Luo Z,Ding ZJ,Zhang QY,Mu HL,Cao YF,Ouyang SH,Kurihara H,Li YF,Sun WY,Li M,He RR

Thu Sep 01 00:00:00 EDT 2022

Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.

Signal transduction and targeted therapy

Meng Y,Qiu L,Zeng X,Hu X,Zhang Y,Wan X,Mao X,Wu J,Xu Y,Xiong Q,Chen Z,Zhang B,Han J

Fri Dec 09 00:00:00 EST 2022

Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.

eLife

Fu J,Zhou M,Gritsenko MA,Nakayasu ES,Song L,Luo ZQ

Thu Jan 27 00:00:00 EST 2022

Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice.

International journal of molecular sciences

Huang YH,Wang FS,Wang PW,Lin HY,Luo SD,Yang YL

Wed Jan 05 00:00:00 EST 2022

A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.

Acta neuropathologica

Shang Y,Sun X,Chen X,Wang Q,Wang EJ,Miller E,Xu R,Pieper AA,Qi X

Tue Nov 01 00:00:00 EDT 2022

Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation.

International journal of molecular sciences

Yang S,Du Y,Zhao X,Tang Q,Su W,Hu Y,Yu P

Wed May 11 00:00:00 EDT 2022

Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.

Cell & bioscience

Yao Y,Ren Z,Yang R,Mei Y,Dai Y,Cheng Q,Xu C,Xu X,Wang S,Kim KM,Noh JH,Zhu J,Zhao N,Liu YU,Mao G,Sima J

Fri Nov 04 00:00:00 EDT 2022

PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway.

Cell death and differentiation

Wang Y,Yan S,Liu X,Deng F,Wang P,Yang L,Hu L,Huang K,He J

Sat Oct 01 00:00:00 EDT 2022

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Sat May 07 00:00:00 EDT 2022

CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.

Proceedings of the National Academy of Sciences of the United States of America

Yu J,Liufu T,Zheng Y,Xu J,Meng L,Zhang W,Yuan Y,Hong D,Charlet-Berguerand N,Wang Z,Deng J

Tue Oct 11 00:00:00 EDT 2022

Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.

Inflammation

Zeng L,He J,Liu C,Zhang F,Zhang Z,Chen H,Wang Q,Ding X,Luo H

Fri Apr 01 00:00:00 EDT 2022

Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.

Life science alliance

Rusilowicz-Jones EV,Barone FG,Lopes FM,Stephen E,Mortiboys H,Urbé S,Clague MJ

Tue Feb 01 00:00:00 EST 2022

Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.

Oxidative medicine and cellular longevity

Ren C,Hu C,Wu Y,Li T,Zou A,Yu D,Shen T,Cai W,Yu J

Fri Jul 29 00:00:00 EDT 2022

The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.

Cells

Liao Z,Gong Z,Wang Z,Yang W,Liu W,Hou L,Liu X,Hua J,Wang B,Li N

Tue Aug 30 00:00:00 EDT 2022

The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP.

Cells

Liao Z,Gong Z,Wang Z,Yang W,Liu W,Hou L,Liu X,Hua J,Wang B,Li N

Tue Aug 30 00:00:00 EDT 2022

Mitochondrial PARP1 regulates NAD⁺-dependent poly ADP-ribosylation of mitochondrial nucleoids.

Experimental & molecular medicine

Lee JH,Hussain M,Kim EW,Cheng SJ,Leung AKL,Fakouri NB,Croteau DL,Bohr VA

Thu Dec 01 00:00:00 EST 2022

PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles.

Journal of nanobiotechnology

Fan Y,Cheng Z,Mao L,Xu G,Li N,Zhang M,Weng P,Zheng L,Dong X,Hu S,Wang B,Qin X,Jiang X,Chen C,Zhang J,Zou Z

Sat Mar 19 00:00:00 EDT 2022

Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Jin L,Yu B,Liu G,Nie W,Wang J,Chen J,Xiao L,Xia H,Han F,Yang Y

Wed Jun 01 00:00:00 EDT 2022

Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Jin L,Yu B,Liu G,Nie W,Wang J,Chen J,Xiao L,Xia H,Han F,Yang Y

Wed Jun 01 00:00:00 EDT 2022

Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Jin L,Yu B,Liu G,Nie W,Wang J,Chen J,Xiao L,Xia H,Han F,Yang Y

Wed Jun 01 00:00:00 EDT 2022

Mitophagy induced by UMI-77 preserves mitochondrial fitness in renal tubular epithelial cells and alleviates renal fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Jin L,Yu B,Liu G,Nie W,Wang J,Chen J,Xiao L,Xia H,Han F,Yang Y

Wed Jun 01 00:00:00 EDT 2022

The TLR-chaperone CNPY3 is a critical regulator of NLRP3-inflammasome activation.

European journal of immunology

Ghait M,Husain RA,Duduskar SN,Haack TB,Rooney M,Göhrig B,Bauer M,Rubio I,Deshmukh SD

Wed Jun 01 00:00:00 EDT 2022

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.

Diabetes

Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L

Sun May 01 00:00:00 EDT 2022

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.

Diabetes

Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L

Sun May 01 00:00:00 EDT 2022

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.

Diabetes

Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L

Sun May 01 00:00:00 EDT 2022

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.

Diabetes

Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L

Sun May 01 00:00:00 EDT 2022

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage.

Developmental cell

Cao K,Riley JS,Heilig R,Montes-Gómez AE,Vringer E,Berthenet K,Cloix C,Elmasry Y,Spiller DG,Ichim G,Campbell KJ,Gilmore AP,Tait SWG

Mon May 23 00:00:00 EDT 2022

The Valuable Role of ARMC1 in Invasive Breast Cancer as a Novel Biomarker.

BioMed research international

Gan Y,Zhong F,Wang H,Li L

Thu Apr 07 00:00:00 EDT 2022

Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma.

Cancer science

Yang C,Cui XW,Ding ZW,Jiang TY,Feng XF,Pan YF,Lin YK,Shang TY,Wang Q,Pan J,Wang J,Wang HY,Dong LW

Thu Dec 01 00:00:00 EST 2022

Low-dose metformin targets the lysosomal AMPK pathway through PEN2.

Nature

Ma T,Tian X,Zhang B,Li M,Wang Y,Yang C,Wu J,Wei X,Qu Q,Yu Y,Long S,Feng JW,Li C,Zhang C,Xie C,Wu Y,Xu Z,Chen J,Yu Y,Huang X,He Y,Yao L,Zhang L,Zhu M,Wang W,Wang ZC,Zhang M,Bao Y,Jia W,Lin SY,Ye Z,Piao HL,Deng X,Zhang CS,Lin SC

Tue Mar 01 00:00:00 EST 2022

Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons.

Cells

López-Molina L,Fernández-Irigoyen J,Cifuentes-Díaz C,Alberch J,Girault JA,Santamaría E,Ginés S,Giralt A

Tue Mar 01 00:00:00 EST 2022

The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration.

Cells

Mavinga M,Palmier M,Rémy M,Jeannière C,Lenoir S,Rey S,Saint-Marc M,Alonso F,Génot E,Thébaud N,Chevret E,Mournetas V,Rousseau B,Boiziau C,Boeuf H

Fri Dec 16 00:00:00 EST 2022

The combination of nuclear receptor NR1D1 and ULK1 promotes mitophagy in adipocytes to ameliorate obesity.

Adipocyte

Yu B,Pan JB,Yu FY

Thu Dec 01 00:00:00 EST 2022

Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles.

Acta pharmacologica Sinica

Li YJ,Liu RP,Ding MN,Zheng Q,Wu JZ,Xue XY,Gu YQ,Ma BN,Cai YJ,Li S,Lin S,Zhang LY,Li X

Mon Aug 01 00:00:00 EDT 2022

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.

The Journal of biological chemistry

Sun S,Hou H,Ma G,Ma Q,Li N,Zhang L,Dong C,Cao M,Tam KY,Ying Z,Wang H

Thu Dec 01 00:00:00 EST 2022

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.

The Journal of biological chemistry

Sun S,Hou H,Ma G,Ma Q,Li N,Zhang L,Dong C,Cao M,Tam KY,Ying Z,Wang H

Thu Dec 01 00:00:00 EST 2022

Delivery of engineered extracellular vesicles with miR-29b editing system for muscle atrophy therapy.

Journal of nanobiotechnology

Chen R,Yuan W,Zheng Y,Zhu X,Jin B,Yang T,Yan Y,Xu W,Chen H,Gao J,Li G,Gokulnath P,Vulugundam G,Li J,Xiao J

Mon Jun 27 00:00:00 EDT 2022

Exogenous Otx2 protects midbrain dopaminergic neurons from MPP⁺ by interacting with ATP5a1 and promoting ATP synthesis.

Neurotoxicology

Xue J,Li Y,Qi Y,Zhang Z,Tang X

Fri Jul 01 00:00:00 EDT 2022

Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer.

Molecular cell

Cieśla M,Ngoc PCT,Cordero E,Martinez ÁS,Morsing M,Muthukumar S,Beneventi G,Madej M,Munita R,Jönsson T,Lövgren K,Ebbesson A,Nodin B,Hedenfalk I,Jirström K,Vallon-Christersson J,Honeth G,Staaf J,Incarnato D,Pietras K,Bosch A,Bellodi C

Thu Apr 01 00:00:00 EDT 2021

MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.

EMBO reports

Wang F,Chen X,Cheng H,Song L,Liu J,Caplan S,Zhu L,Wu JY

Mon Jul 05 00:00:00 EDT 2021

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.

The Journal of cell biology

Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M

Mon Jun 07 00:00:00 EDT 2021

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.

The Journal of cell biology

Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M

Mon Jun 07 00:00:00 EDT 2021

OPA1 Modulates Mitochondrial Ca²⁺ Uptake Through ER-Mitochondria Coupling.

Frontiers in cell and developmental biology

Cartes-Saavedra B,Macuada J,Lagos D,Arancibia D,Andrés ME,Yu-Wai-Man P,Hajnóczky G,Eisner V

Wed Feb 16 00:00:00 EST 2022

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

Human molecular genetics

Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ

Thu Jun 17 00:00:00 EDT 2021

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

Human molecular genetics

Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ

Thu Jun 17 00:00:00 EDT 2021

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

Human molecular genetics

Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ

Thu Jun 17 00:00:00 EDT 2021

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

Human molecular genetics

Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ

Thu Jun 17 00:00:00 EDT 2021

Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.

Theranostics

Luo Q,Xian P,Wang T,Wu S,Sun T,Wang W,Wang B,Yang H,Yang Y,Wang H,Liu W,Long Q

Fri Jul 30 00:00:00 EDT 2021

The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro.

Archives of toxicology

Haasler L,Kondadi AK,Tsigaras T,von Montfort C,Graf P,Stahl W,Brenneisen P

Thu Apr 01 00:00:00 EDT 2021

Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.

Oxidative medicine and cellular longevity

Zhao R,Wang B,Wang D,Wu B,Ji P,Tan D

Thu May 20 00:00:00 EDT 2021

MYO1F Regulates IgE and MRGPRX2-Dependent Mast Cell Exocytosis.

Journal of immunology (Baltimore, Md. : 1950)

Navinés-Ferrer A,Ainsua-Enrich E,Serrano-Candelas E,Proaño-Pérez E,Muñoz-Cano R,Gastaminza G,Olivera A,Martin M

Sat May 15 00:00:00 EDT 2021

Facile Synthesis of Antibody-Coupled Polydopamine-Coated Magnetic Graphene Oxide Composites for Efficient Immunopurification and Metabolomics Analysis of Mitochondria.

Analytical chemistry

Chang M,Wang Q,Liu X,Shi X,Xu G

Tue Aug 17 00:00:00 EDT 2021

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer.

eLife

McGuirk S,Audet-Delage Y,Annis MG,Xue Y,Vernier M,Zhao K,St-Louis C,Minarrieta L,Patten DA,Morin G,Greenwood CM,Giguère V,Huang S,Siegel PM,St-Pierre J

Mon Jun 28 00:00:00 EDT 2021

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Autophagy

Huang T,Xu T,Wang Y,Zhou Y,Yu D,Wang Z,He L,Chen Z,Zhang Y,Davidson D,Dai Y,Hang C,Liu X,Yan C

Mon Nov 01 00:00:00 EDT 2021

Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime.

ACS chemical neuroscience

Liu X,Wei Q,Yang X,Wang X,Zhang J,Xu R,Zhang H,Wang S,Wan X,Jiang L,He Y,Li S,Chen R,Wang Y,Chen Y,Qin F,Chen Y,Dai Y,Li H,Zhao Y,Zhang H,Bu Q,Wang H,Tian J,Zhao Y,Cen X

Wed Dec 01 00:00:00 EST 2021

Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.

FEBS letters

Qin S,Ye L,Zheng Y,Gao J

Mon Feb 01 00:00:00 EST 2021

TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation.

Autophagy

Tu C,Li H,Liu X,Wang Y,Li W,Meng L,Wang W,Li Y,Li D,Du J,Lu G,Lin G,Tan YQ

Mon Nov 01 00:00:00 EDT 2021

TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation.

Autophagy

Tu C,Li H,Liu X,Wang Y,Li W,Meng L,Wang W,Li Y,Li D,Du J,Lu G,Lin G,Tan YQ

Mon Nov 01 00:00:00 EDT 2021

Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells.

Scientific reports

Haschler TN,Horsley H,Balys M,Anderson G,Taanman JW,Unwin RJ,Norman JT

Fri Jul 30 00:00:00 EDT 2021

Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy.

Autophagy

Wang R,Zhu Y,Ren C,Yang S,Tian S,Chen H,Jin M,Zhou H

Mon Feb 01 00:00:00 EST 2021

FUNDC1 inhibits NLRP3-mediated inflammation after intracerebral hemorrhage by promoting mitophagy in mice.

Neuroscience letters

Zheng S,Jian D,Gan H,Wang L,Zhao J,Zhai X

Mon Jun 21 00:00:00 EDT 2021

Butyrate Feeding Reverses CypD-Related Mitoflash Phenotypes in Mouse Myofibers.

International journal of molecular sciences

Li A,Li X,Yi J,Ma J,Zhou J

Sat Jul 10 00:00:00 EDT 2021

Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model.

Journal of Alzheimer's disease : JAD

Yang L,Wu C,Tucker L,Dong Y,Li Y,Xu P,Zhang Q

Thu Dec 16 00:00:00 EST 2021

PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage.

Autophagy

Liu W,Xu L,Wang X,Zhang D,Sun G,Wang M,Wang M,Han Y,Chai R,Wang H

Wed Dec 01 00:00:00 EST 2021

Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.

Biological & pharmaceutical bulletin

Ren Y,Lin Y,Chen J,Jin Y

Fri Jan 28 00:00:00 EST 2022

Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.

Toxicology and applied pharmacology

Hirano T,Suzuki N,Ikenaka Y,Hoshi N,Tabuchi Y

Mon Nov 01 00:00:00 EDT 2021

Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition.

Toxicology and applied pharmacology

Hirano T,Suzuki N,Ikenaka Y,Hoshi N,Tabuchi Y

Mon Nov 01 00:00:00 EDT 2021

Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress.

Molecular cell

Jobava R,Mao Y,Guan BJ,Hu D,Krokowski D,Chen CW,Shu XE,Chukwurah E,Wu J,Gao Z,Zagore LL,Merrick WC,Trifunovic A,Hsieh AC,Valadkhan S,Zhang Y,Qi X,Jankowsky E,Topisirovic I,Licatalosi DD,Qian SB,Hatzoglou M

Thu Oct 21 00:00:00 EDT 2021

Proteomic analysis of the exosomes secreted from Ctenopharyngodon idellus kidney cells infected with grass carp reovirus reveals their involvement in the cellular responses to viral infection.

Fish physiology and biochemistry

Zhang X,Zhang Y,Pan J,Zhu M,Liang Z,Shen Z,Dai K,Yan B,Dai Y,Xue R,Cao G,Hu X,Gong C

Sun Aug 01 00:00:00 EDT 2021

Machine learning-based classification of mitochondrial morphology in primary neurons and brain.

Scientific reports

Fogo GM,Anzell AR,Maheras KJ,Raghunayakula S,Wider JM,Emaus KJ,Bryson TD,Bukowski MJ,Neumar RW,Przyklenk K,Sanderson TH

Thu Mar 04 00:00:00 EST 2021

PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.

International journal of molecular sciences

Li Y,Kang J,Fu J,Luo H,Liu Y,Li Y,Sun L

Wed Mar 03 00:00:00 EST 2021

Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats.

Brain research

Peng G,Zheng H,Wu C,Wu C,Ma X,Xiong J,Hou J,Zhang L,Yang L,Pan H

Wed Dec 01 00:00:00 EST 2021

The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.

International journal of molecular sciences

Khodayari N,Wang RL,Oshins R,Lu Y,Millett M,Aranyos AM,Mostofizadeh S,Scindia Y,Flagg TO,Brantly M

Thu Dec 09 00:00:00 EST 2021

Remote Ischemic Postconditioning Inhibited Mitophagy to Achieve Neuroprotective Effects in the Rat Model of Cardiac Arrest.

Neurochemical research

Huang Y,Gao X,Zhou X,Zhang Y,Tan Z,Zhu S

Mon Mar 01 00:00:00 EST 2021

Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.

Nucleic acids research

Zhang Q,He X,Yao S,Lin T,Zhang L,Chen D,Chen C,Yang Q,Li F,Zhu YM,Guan MX

Fri May 07 00:00:00 EDT 2021

USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.

The Journal of cell biology

Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J

Mon Jul 05 00:00:00 EDT 2021

USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.

The Journal of cell biology

Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J

Mon Jul 05 00:00:00 EDT 2021

Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore-forming toxins to Caenorhabditis elegans.

Environmental microbiology

Shi J,Zhang F,Chen L,Bravo A,Soberón M,Sun M

Wed Sep 01 00:00:00 EDT 2021

Spike Proteins of SARS-CoV-2 Induce Pathological Changes in Molecular Delivery and Metabolic Function in the Brain Endothelial Cells.

Viruses

Kim ES,Jeon MT,Kim KS,Lee S,Kim S,Kim DG

Fri Oct 08 00:00:00 EDT 2021

Tubular Mas receptor mediates lipid-induced kidney injury.

Cell death & disease

Kong Y,Zhao X,Qiu M,Lin Y,Feng P,Li S,Liang B,Zhu Q,Huang H,Li C,Wang W

Thu Jan 21 00:00:00 EST 2021

Tubular Mas receptor mediates lipid-induced kidney injury.

Cell death & disease

Kong Y,Zhao X,Qiu M,Lin Y,Feng P,Li S,Liang B,Zhu Q,Huang H,Li C,Wang W

Thu Jan 21 00:00:00 EST 2021

Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.

Nature communications

Hu D,Sun X,Magpusao A,Fedorov Y,Thompson M,Wang B,Lundberg K,Adams DJ,Qi X

Mon Sep 06 00:00:00 EDT 2021

Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.

Mitochondrion

Xie QE,Wang MY,Cao ZP,Du X,Ji DM,Liang D,Cao YX,Liu YJ

Mon Nov 01 00:00:00 EDT 2021

The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells.

Molecular biology of the cell

Bhagawati M,Arroum T,Webeling N,Montoro AG,Mootz HD,Busch KB

Fri Oct 01 00:00:00 EDT 2021

Influence of Subcellular Localization and Functional State on Protein Turnover.

Cells

Yousefi R,Jevdokimenko K,Kluever V,Pacheu-Grau D,Fornasiero EF

Sat Jul 10 00:00:00 EDT 2021

Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N⁶-Methyladenosine Modification.

Frontiers in cell and developmental biology

Lv Y,Li T,Yang M,Su L,Zhu Z,Zhao S,Zeng W,Zheng Y

Tue Jun 22 00:00:00 EDT 2021

Mitochondrial transfer from induced pluripotent stem cells rescues developmental potential of in vitro fertilized embryos from aging females†.

Biology of reproduction

Zhang C,Tao L,Yue Y,Ren L,Zhang Z,Wang X,Tian J,An L

Fri May 07 00:00:00 EDT 2021

Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties.

Cell calcium

Huntington TE,Srinivasan R

Tue Jun 01 00:00:00 EDT 2021

Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells.

Nature communications

Della-Flora Nunes G,Wilson ER,Marziali LN,Hurley E,Silvestri N,He B,O'Malley BW,Beirowski B,Poitelon Y,Wrabetz L,Feltri ML

Wed Jun 02 00:00:00 EDT 2021

Lactobacillus rhamnosus GR-1 Prevents Escherichia coli-Induced Apoptosis Through PINK1/Parkin-Mediated Mitophagy in Bovine Mastitis.

Frontiers in immunology

Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J

Wed Dec 22 00:00:00 EST 2021

Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.

Theranostics

Yang L,Dong Y,Wu C,Youngblood H,Li Y,Zong X,Li L,Xu T,Zhang Q

Thu Jul 22 00:00:00 EDT 2021

Monitoring mitochondrial translation in living cells.

EMBO reports

Yousefi R,Fornasiero EF,Cyganek L,Montoya J,Jakobs S,Rizzoli SO,Rehling P,Pacheu-Grau D

Wed Apr 07 00:00:00 EDT 2021

Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation.

Biology

Mollo N,Esposito M,Aurilia M,Scognamiglio R,Accarino R,Bonfiglio F,Cicatiello R,Charalambous M,Procaccini C,Micillo T,Genesio R,Calì G,Secondo A,Paladino S,Matarese G,De Vita G,Conti A,Nitsch L,Izzo A

Wed Jun 30 00:00:00 EDT 2021

A novel homozygous frameshift mutation in MNS1 associated with severe oligoasthenoteratozoospermia in humans.

Asian journal of andrology

Li Y,Wang WL,Tu CF,Meng LL,Hu TY,Du J,Lin G,Nie HC,Tan YQ

Mon Nov 29 00:00:00 EST 2021

Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.

Environmental toxicology

Xu K,Lu C,Ren X,Wang J,Xu P,Zhang Y

Mon Nov 01 00:00:00 EDT 2021

ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA.

The EMBO journal

Shu L,Hu C,Xu M,Yu J,He H,Lin J,Sha H,Lu B,Engelender S,Guan M,Song Z

Thu Apr 15 00:00:00 EDT 2021

ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA.

The EMBO journal

Shu L,Hu C,Xu M,Yu J,He H,Lin J,Sha H,Lu B,Engelender S,Guan M,Song Z

Thu Apr 15 00:00:00 EDT 2021

Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1.

Journal of cell science

Queliconi BB,Kojima W,Kimura M,Imai K,Udagawa C,Motono C,Hirokawa T,Tashiro S,Caaveiro JMM,Tsumoto K,Yamano K,Tanaka K,Matsuda N

Mon Nov 15 00:00:00 EST 2021

Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1.

Journal of cell science

Queliconi BB,Kojima W,Kimura M,Imai K,Udagawa C,Motono C,Hirokawa T,Tashiro S,Caaveiro JMM,Tsumoto K,Yamano K,Tanaka K,Matsuda N

Mon Nov 15 00:00:00 EST 2021

Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.

Science translational medicine

Zhang XJ,She ZG,Wang J,Sun D,Shen LJ,Xiang H,Cheng X,Ji YX,Huang YP,Li PL,Yang X,Cheng Y,Ma JP,Wang HP,Hu Y,Hu F,Tian S,Tian H,Zhang P,Zhao GN,Wang L,Hu ML,Yang Q,Zhu LH,Cai J,Yang J,Zhang X,Ma X,Xu Q,Touyz RM,Liu PP,Loomba R,Wang Y,Li H

Wed Dec 15 00:00:00 EST 2021

Age-Dependent Decline in Neuron Growth Potential and Mitochondria Functions in Cortical Neurons.

Cells

Sutherland TC,Sefiani A,Horvat D,Huntington TE,Lei Y,West AP,Geoffroy CG

Tue Jun 29 00:00:00 EDT 2021

TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis.

Cell death & disease

Chen H,He A,Li H,Chen H,Xie H,Luo L,Huang Y,Chen J,Guan J,He Q,Ma J,Ou C,Tao A,Yan J

Wed Oct 13 00:00:00 EDT 2021

Active RNA interference in mitochondria.

Cell research

Gao K,Cheng M,Zuo X,Lin J,Hoogewijs K,Murphy MP,Fu XD,Zhang X

Mon Feb 01 00:00:00 EST 2021

A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.

Cellular and molecular gastroenterology and hepatology

Sun D,Niu Z,Zheng HX,Wu F,Jiang L,Han TQ,Wei Y,Wang J,Jin L

Mon Mar 07 00:00:00 EST 2022

Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.

Redox biology

Han X,Xu T,Fang Q,Zhang H,Yue L,Hu G,Sun L

Sun Aug 01 00:00:00 EDT 2021

Cilia locally synthesize proteins to sustain their ultrastructure and functions.

Nature communications

Hao K,Chen Y,Yan X,Zhu X

Tue Nov 30 00:00:00 EST 2021

Cilia locally synthesize proteins to sustain their ultrastructure and functions.

Nature communications

Hao K,Chen Y,Yan X,Zhu X

Tue Nov 30 00:00:00 EST 2021

Inhibition of ceramide de novo synthesis ameliorates meibomian gland dysfunction induced by SCD1 deficiency.

The ocular surface

Ji C,Guo Y,Liu Y,Xu S,Zhao S,Luo X,Qiu F,Huang R,Xu Q,Zheng R,Xia M,Zhao Y,Ren J,Qiu Y

Fri Oct 01 00:00:00 EDT 2021

Inhibition of ceramide de novo synthesis ameliorates meibomian gland dysfunction induced by SCD1 deficiency.

The ocular surface

Ji C,Guo Y,Liu Y,Xu S,Zhao S,Luo X,Qiu F,Huang R,Xu Q,Zheng R,Xia M,Zhao Y,Ren J,Qiu Y

Fri Oct 01 00:00:00 EDT 2021

The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy.

FEBS open bio

Liu D,Sun Z,Ye T,Li J,Zeng B,Zhao Q,Wang J,Xing HR

Thu Jul 01 00:00:00 EDT 2021

Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.

Biochemical pharmacology

Sun H,Ou T,Hu J,Yang Z,Lei Q,Li Y,Wang G,Li Y,Wu K,Wang S,Wu S

Sun Aug 01 00:00:00 EDT 2021

Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.

Biochemical pharmacology

Sun H,Ou T,Hu J,Yang Z,Lei Q,Li Y,Wang G,Li Y,Wu K,Wang S,Wu S

Sun Aug 01 00:00:00 EDT 2021

25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.

International immunopharmacology

Cao Q,Luo J,Xiong Y,Liu Z,Ye Q

Thu Jul 01 00:00:00 EDT 2021

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.

Nature cell biology

Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC

Mon Mar 01 00:00:00 EST 2021

Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation.

International immunopharmacology

Zhang C,Li X,Hu X,Xu Q,Zhang Y,Liu H,Diao Y,Zhang X,Li L,Yu J,Yin H,Peng J

Thu Apr 01 00:00:00 EDT 2021

Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation.

International immunopharmacology

Zhang C,Li X,Hu X,Xu Q,Zhang Y,Liu H,Diao Y,Zhang X,Li L,Yu J,Yin H,Peng J

Thu Apr 01 00:00:00 EDT 2021

Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation.

Redox report : communications in free radical research

Meng Q,Zaharieva EK,Sasatani M,Kobayashi J

Wed Dec 01 00:00:00 EST 2021

Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.

Redox biology

Song N,Fang Y,Zhu H,Liu J,Jiang S,Sun S,Xu R,Ding J,Hu G,Lu M

Mon Nov 01 00:00:00 EDT 2021

Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.

The Journal of infection

Song Y,Dong Y,Liao Y,Liang Z,Yao J,Zhou X

Thu Jul 01 00:00:00 EDT 2021

Tongluo Yishen Decoction Ameliorates Renal Fibrosis via Regulating Mitochondrial Dysfunction Induced by Oxidative Stress in Unilateral Ureteral Obstruction Rats.

Frontiers in pharmacology

Jia Q,Han L,Zhang X,Yang W,Gao Y,Shen Y,Li B,Wang S,Qin M,Lowe S,Qin J,Hao G

Sat Oct 30 00:00:00 EDT 2021

Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation.

Theranostics

Liu C,Wang L,Liu X,Tan Y,Tao L,Xiao Y,Deng P,Wang H,Deng Q,Lin Y,Jie H,Zhang H,Zhang J,Peng Y,Zhang H,Zhou Z,Sun Q,Cen X,Zhao Y

Tue Jul 27 00:00:00 EDT 2021

An in vitro system to silence mitochondrial gene expression.

Cell

Cruz-Zaragoza LD,Dennerlein S,Linden A,Yousefi R,Lavdovskaia E,Aich A,Falk RR,Gomkale R,Schöndorf T,Bohnsack MT,Richter-Dennerlein R,Urlaub H,Rehling P

Thu Nov 11 00:00:00 EST 2021

An in vitro system to silence mitochondrial gene expression.

Cell

Cruz-Zaragoza LD,Dennerlein S,Linden A,Yousefi R,Lavdovskaia E,Aich A,Falk RR,Gomkale R,Schöndorf T,Bohnsack MT,Richter-Dennerlein R,Urlaub H,Rehling P

Thu Nov 11 00:00:00 EST 2021

The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.

The Journal of cell biology

Labbé K,Mookerjee S,Le Vasseur M,Gibbs E,Lerner C,Nunnari J

Mon Nov 01 00:00:00 EDT 2021

The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.

The Journal of cell biology

Labbé K,Mookerjee S,Le Vasseur M,Gibbs E,Lerner C,Nunnari J

Mon Nov 01 00:00:00 EDT 2021

Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.

Frontiers in cardiovascular medicine

Zhang J,Feng W,Li M,Chen P,Ning X,Ou C,Chen M

Fri Nov 26 00:00:00 EST 2021

Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii.

Scientific reports

Tiku V,Kofoed EM,Yan D,Kang J,Xu M,Reichelt M,Dikic I,Tan MW

Tue Jan 12 00:00:00 EST 2021

Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.

Neuropharmacology

Wang M,Wan C,He T,Han C,Zhu K,Waddington JL,Zhen X

Wed Sep 15 00:00:00 EDT 2021

Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice.

American journal of human genetics

He X,Liu C,Yang X,Lv M,Ni X,Li Q,Cheng H,Liu W,Tian S,Wu H,Gao Y,Yang C,Tan Q,Cong J,Tang D,Zhang J,Song B,Zhong Y,Li H,Zhi W,Mao X,Fu F,Ge L,Shen Q,Zhang M,Saiyin H,Jin L,Xu Y,Zhou P,Wei Z,Zhang F,Cao Y

Thu Sep 03 00:00:00 EDT 2020

Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.

Science China. Life sciences

Liu X,Wang X,Li J,Hu S,Deng Y,Yin H,Bao X,Zhang QC,Wang G,Wang B,Shi Q,Shan G

Thu Oct 01 00:00:00 EDT 2020

Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.

Science China. Life sciences

Liu X,Wang X,Li J,Hu S,Deng Y,Yin H,Bao X,Zhang QC,Wang G,Wang B,Shi Q,Shan G

Thu Oct 01 00:00:00 EDT 2020

The oligosaccharide portion of ganglioside GM1 regulates mitochondrial function in neuroblastoma cells.

Glycoconjugate journal

Fazzari M,Audano M,Lunghi G,Di Biase E,Loberto N,Mauri L,Mitro N,Sonnino S,Chiricozzi E

Mon Jun 01 00:00:00 EDT 2020

The oligosaccharide portion of ganglioside GM1 regulates mitochondrial function in neuroblastoma cells.

Glycoconjugate journal

Fazzari M,Audano M,Lunghi G,Di Biase E,Loberto N,Mauri L,Mitro N,Sonnino S,Chiricozzi E

Mon Jun 01 00:00:00 EDT 2020

Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.

Science advances

Zhang X,Wang R,Hu D,Sun X,Fujioka H,Lundberg K,Chan ER,Wang Q,Xu R,Flanagan ME,Pieper AA,Qi X

Tue Dec 01 00:00:00 EST 2020

Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.

Science advances

Zhang X,Wang R,Hu D,Sun X,Fujioka H,Lundberg K,Chan ER,Wang Q,Xu R,Flanagan ME,Pieper AA,Qi X

Tue Dec 01 00:00:00 EST 2020

FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses.

Journal of radiation research

Qi F,Meng Q,Hayashi I,Kobayashi J

Fri May 22 00:00:00 EDT 2020

Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration.

The Journal of clinical investigation

Jauhari A,Baranov SV,Suofu Y,Kim J,Singh T,Yablonska S,Li F,Wang X,Oberly P,Minnigh MB,Poloyac SM,Carlisle DL,Friedlander RM

Mon Jun 01 00:00:00 EDT 2020

HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury.

Redox biology

Fu ZJ,Wang ZY,Xu L,Chen XH,Li XX,Liao WT,Ma HK,Jiang MD,Xu TT,Xu J,Shen Y,Song B,Gao PJ,Han WQ,Zhang W

Tue Sep 01 00:00:00 EDT 2020

pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model.

Cell death & disease

Xu X,Ng B,Sim B,Radulescu CI,Yusof NABM,Goh WI,Lin S,Lim JSY,Cha Y,Kusko R,Kay C,Ratovitski T,Ross C,Hayden MR,Wright G,Pouladi MA

Fri Sep 25 00:00:00 EDT 2020

FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li C,Zhou J,Liu Z,Zhou J,Yao W,Tao J,Shen M,Liu H

Sun Mar 01 00:00:00 EST 2020

Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock.

Frontiers in immunology

Sakaguchi N,Sasai M,Bando H,Lee Y,Pradipta A,Ma JS,Yamamoto M

Mon May 03 00:00:00 EDT 2021

OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.

Cell death & disease

Hu C,Shu L,Huang X,Yu J,Li L,Gong L,Yang M,Wu Z,Gao Z,Zhao Y,Chen L,Song Z

Sat Oct 31 00:00:00 EDT 2020

Myotonic Dystrophy type 1 cells display impaired metabolism and mitochondrial dysfunction that are reversed by metformin.

Aging

García-Puga M,Saenz-Antoñanzas A,Fernández-Torrón R,Munain AL,Matheu A

Wed Apr 08 00:00:00 EDT 2020

Hyperlipidemia Affects Tight Junctions and Pump Function in the Corneal Endothelium.

The American journal of pathology

Bu J,Yu J,Wu Y,Cai X,Li K,Tang L,Jiang N,Jeyalatha MV,Zhang M,Sun H,He H,Quantock AJ,Chen Y,Liu Z,Li W

Sun Mar 01 00:00:00 EST 2020

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice.

PLoS genetics

Wang YY,Ke CC,Chen YL,Lin YH,Yu IS,Ku WC,O'Bryan MK,Lin YH

Tue Sep 01 00:00:00 EDT 2020

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice.

PLoS genetics

Wang YY,Ke CC,Chen YL,Lin YH,Yu IS,Ku WC,O'Bryan MK,Lin YH

Tue Sep 01 00:00:00 EDT 2020

Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway.

Oxidative medicine and cellular longevity

Zhao F,Feng LX,Liu Q,Wang HS,Tang CY,Cheng W,Deng YH,Wu X,Yan P,Duan XJ,Peng JC,Duan SB

Mon Jan 04 00:00:00 EST 2021

Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway.

Oxidative medicine and cellular longevity

Zhao F,Feng LX,Liu Q,Wang HS,Tang CY,Cheng W,Deng YH,Wu X,Yan P,Duan XJ,Peng JC,Duan SB

Mon Jan 04 00:00:00 EST 2021

Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway.

Oxidative medicine and cellular longevity

Zhao F,Feng LX,Liu Q,Wang HS,Tang CY,Cheng W,Deng YH,Wu X,Yan P,Duan XJ,Peng JC,Duan SB

Mon Jan 04 00:00:00 EST 2021

Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway.

Oxidative medicine and cellular longevity

Zhao F,Feng LX,Liu Q,Wang HS,Tang CY,Cheng W,Deng YH,Wu X,Yan P,Duan XJ,Peng JC,Duan SB

Mon Jan 04 00:00:00 EST 2021

A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy.

Neuropharmacology

Chen JL,Wang XX,Chen L,Tang J,Xia YF,Qian K,Qin ZH,Waeber C,Sheng R

Tue Dec 15 00:00:00 EST 2020

Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.

Biochemical pharmacology

Gao Y,Li J,Li J,Hu C,Zhang L,Yan J,Li L,Zhang L

Wed Jul 01 00:00:00 EDT 2020

The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress.

The Journal of biological chemistry

Lee H,Smith SB,Sheu SS,Yoon Y

Fri May 08 00:00:00 EDT 2020

PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis.

Autophagy

Yan C,Gong L,Chen L,Xu M,Abou-Hamdan H,Tang M,Désaubry L,Song Z

Sun Mar 01 00:00:00 EST 2020

PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis.

Autophagy

Yan C,Gong L,Chen L,Xu M,Abou-Hamdan H,Tang M,Désaubry L,Song Z

Sun Mar 01 00:00:00 EST 2020

The Mitochondrial Fission Regulator DRP1 Controls Post-Transcriptional Regulation of TNF-α.

Frontiers in cellular and infection microbiology

Gao F,Reynolds MB,Passalacqua KD,Sexton JZ,Abuaita BH,O'Riordan MXD

Thu Jun 17 00:00:00 EDT 2021

The Mitochondrial Fission Regulator DRP1 Controls Post-Transcriptional Regulation of TNF-α.

Frontiers in cellular and infection microbiology

Gao F,Reynolds MB,Passalacqua KD,Sexton JZ,Abuaita BH,O'Riordan MXD

Thu Jun 17 00:00:00 EDT 2021

Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly.

Nature communications

Zhang S,Reljić B,Liang C,Kerouanton B,Francisco JC,Peh JH,Mary C,Jagannathan NS,Olexiouk V,Tang C,Fidelito G,Nama S,Cheng RK,Wee CL,Wang LC,Duek Roggli P,Sampath P,Lane L,Petretto E,Sobota RM,Jesuthasan S,Tucker-Kellogg L,Reversade B,Menschaert G,Sun L,Stroud DA,Ho L

Wed Mar 11 00:00:00 EDT 2020

Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly.

Nature communications

Wed Mar 11 00:00:00 EDT 2020

Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.

Biomolecules

Tokuyama T,Hirai A,Shiiba I,Ito N,Matsuno K,Takeda K,Saito K,Mii K,Matsushita N,Fukuda T,Inatome R,Yanagi S

Fri Mar 13 00:00:00 EDT 2020

Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients.

Biomolecules

Tokuyama T,Hirai A,Shiiba I,Ito N,Matsuno K,Takeda K,Saito K,Mii K,Matsushita N,Fukuda T,Inatome R,Yanagi S

Fri Mar 13 00:00:00 EDT 2020

Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs.

Cell reports

Cabukusta B,Berlin I,van Elsland DM,Forkink I,Spits M,de Jong AWM,Akkermans JJLL,Wijdeven RHM,Janssen GMC,van Veelen PA,Neefjes J

Tue Dec 08 00:00:00 EST 2020

Methylene blue post-treatment improves hypoxia-ischemic recovery in a neonatal rat model.

Neurochemistry international

Zhang G,Lu Y,Yang L,Dong Y,Wen J,Xu J,Zhang Q

Thu Oct 01 00:00:00 EDT 2020

Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes.

Frontiers in neuroscience

Contino S,Suelves N,Vrancx C,Vadukul DM,Payen VL,Stanga S,Bertrand L,Kienlen-Campard P

Wed Feb 10 00:00:00 EST 2021

Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes.

Frontiers in neuroscience

Contino S,Suelves N,Vrancx C,Vadukul DM,Payen VL,Stanga S,Bertrand L,Kienlen-Campard P

Wed Feb 10 00:00:00 EST 2021

Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.

Acta pharmacologica Sinica

Zhang ZL,Wang NN,Ma QL,Chen Y,Yao L,Zhang L,Li QS,Shi MH,Wang HF,Ying Z

Wed Jan 01 00:00:00 EST 2020

Mitophagy in the Hippocampus Is Excessive Activated After Cardiac Arrest and Cardiopulmonary Resuscitation.

Neurochemical research

Huang Y,Gao X,Zhou X,Xie B,Zhang Y,Zhu J,Zhu S

Sat Feb 01 00:00:00 EST 2020

Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca²⁺ efflux and Reactive Oxygen Species (ROS) homeostasis.

Neurobiology of disease

Cherubini M,Lopez-Molina L,Gines S

Sun Mar 01 00:00:00 EST 2020

Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.

Journal of proteome research

Meng K,Lu S,Yan X,Sun Y,Gao J,Wang Y,Yin X,Sun Z,He QY

Fri Mar 06 00:00:00 EST 2020

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

Science (New York, N.Y.)

Gordon DE,Hiatt J,Bouhaddou M,Rezelj VV,Ulferts S,Braberg H,Jureka AS,Obernier K,Guo JZ,Batra J,Kaake RM,Weckstein AR,Owens TW,Gupta M,Pourmal S,Titus EW,Cakir M,Soucheray M,McGregor M,Cakir Z,Jang G,O'Meara MJ,Tummino TA,Zhang Z,Foussard H,Rojc A,Zhou Y,Kuchenov D,Hüttenhain R,Xu J,Eckhardt M,Swaney DL,Fabius JM,Ummadi M,Tutuncuoglu B,Rathore U,Modak M,Haas P,Haas KM,Naing ZZC,Pulido EH,Shi Y,Barrio-Hernandez I,Memon D,Petsalaki E,Dunham A,Marrero MC,Burke D,Koh C,Vallet T,Silvas JA,Azumaya CM,Billesbølle C,Brilot AF,Campbell MG,Diallo A,Dickinson MS,Diwanji D,Herrera N,Hoppe N,Kratochvil HT,Liu Y,Merz GE,Moritz M,Nguyen HC,Nowotny C,Puchades C,Rizo AN,Schulze-Gahmen U,Smith AM,Sun M,Young ID,Zhao J,Asarnow D,Biel J,Bowen A,Braxton JR,Chen J,Chio CM,Chio US,Deshpande I,Doan L,Faust B,Flores S,Jin M,Kim K,Lam VL,Li F,Li J,Li YL,Li Y,Liu X,Lo M,Lopez KE,Melo AA,Moss FR,Nguyen P,Paulino J,Pawar KI,Peters JK,Pospiech TH,Safari M,Sangwan S,Schaefer K,Thomas PV,Thwin AC,Trenker R,Tse E,Tsui TKM,Wang F,Whitis N,Yu Z,Zhang K,Zhang Y,Zhou F,Saltzberg D,Hodder AJ,Shun-Shion AS,Williams DM,White KM,Rosales R,Kehrer T,Miorin L,Moreno E,Patel AH,Rihn S,Khalid MM,Vallejo-Gracia A,Fozouni P,Simoneau CR,Roth TL,Wu D,Karim MA,Ghoussaini M,Dunham I,Berardi F,Weigang S,Chazal M,Park J,Logue J,McGrath M,Weston S,Haupt R,Hastie CJ,Elliott M,Brown F,Burness KA,Reid E,Dorward M,Johnson C,Wilkinson SG,Geyer A,Giesel DM,Baillie C,Raggett S,Leech H,Toth R,Goodman N,Keough KC,Lind AL,Klesh RJ,Hemphill KR,Carlson-Stevermer J,Oki J,Holden K,Maures T,Pollard KS,Sali A,Agard DA,Cheng Y,Fraser JS,Frost A,Jura N,Kortemme T,Manglik A,Southworth DR,Stroud RM,Alessi DR,Davies P,Frieman MB,Ideker T,Abate C,Jouvenet N,Kochs G,Shoichet B,Ott M,Palmarini M,Shokat KM,García-Sastre A,Rassen JA,Grosse R,Rosenberg OS,Verba KA,Basler CF,Vignuzzi M,Peden AA,Beltrao P,Krogan NJ

Fri Dec 04 00:00:00 EST 2020

Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease.

Experimental cell research

Xiong X,Li S,Han TL,Zhou F,Zhang X,Tian M,Tang L,Li Y

Sun Nov 01 00:00:00 EDT 2020

Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease.

Experimental cell research

Xiong X,Li S,Han TL,Zhou F,Zhang X,Tian M,Tang L,Li Y

Sun Nov 01 00:00:00 EDT 2020

Human CLPB forms ATP-dependent complexes in the mitochondrial intermembrane space.

The international journal of biochemistry & cell biology

Thevarajan I,Zolkiewski M,Zolkiewska A

Thu Oct 01 00:00:00 EDT 2020

Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission.

Frontiers in pharmacology

Song N,Zhu H,Xu R,Liu J,Fang Y,Zhang J,Ding J,Hu G,Lu M

Mon Apr 17 00:00:00 EDT 2023

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Cell metabolism

Zhong X,Cui P,Cai Y,Wang L,He X,Long P,Lu K,Yan R,Zhang Y,Pan X,Zhao X,Li W,Zhang H,Zhou Q,Gao P

Tue Apr 02 00:00:00 EDT 2019

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Cell metabolism

Zhong X,Cui P,Cai Y,Wang L,He X,Long P,Lu K,Yan R,Zhang Y,Pan X,Zhao X,Li W,Zhang H,Zhou Q,Gao P

Tue Apr 02 00:00:00 EDT 2019

β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 mice.

EMBO molecular medicine

Hidalgo-Gutiérrez A,Barriocanal-Casado E,Bakkali M,Díaz-Casado ME,Sánchez-Maldonado L,Romero M,Sayed RK,Prehn C,Escames G,Duarte J,Acuña-Castroviejo D,López LC

Tue Jan 01 00:00:00 EST 2019

β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 mice.

EMBO molecular medicine

Hidalgo-Gutiérrez A,Barriocanal-Casado E,Bakkali M,Díaz-Casado ME,Sánchez-Maldonado L,Romero M,Sayed RK,Prehn C,Escames G,Duarte J,Acuña-Castroviejo D,López LC

Tue Jan 01 00:00:00 EST 2019

Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations.

Autophagy

Li H,Ham A,Ma TC,Kuo SH,Kanter E,Kim D,Ko HS,Quan Y,Sardi SP,Li A,Arancio O,Kang UJ,Sulzer D,Tang G

Tue Jan 01 00:00:00 EST 2019

Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations.

Autophagy

Li H,Ham A,Ma TC,Kuo SH,Kanter E,Kim D,Ko HS,Quan Y,Sardi SP,Li A,Arancio O,Kang UJ,Sulzer D,Tang G

Tue Jan 01 00:00:00 EST 2019

Mitochondria modulate programmed neuritic retraction.

Proceedings of the National Academy of Sciences of the United States of America

Baranov SV,Baranova OV,Yablonska S,Suofu Y,Vazquez AL,Kozai TDY,Cui XT,Ferrando LM,Larkin TM,Tyurina YY,Kagan VE,Carlisle DL,Kristal BS,Friedlander RM

Tue Jan 08 00:00:00 EST 2019

Mitochondria modulate programmed neuritic retraction.

Proceedings of the National Academy of Sciences of the United States of America

Baranov SV,Baranova OV,Yablonska S,Suofu Y,Vazquez AL,Kozai TDY,Cui XT,Ferrando LM,Larkin TM,Tyurina YY,Kagan VE,Carlisle DL,Kristal BS,Friedlander RM

Tue Jan 08 00:00:00 EST 2019

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

The Journal of cell biology

Richter F,Dennerlein S,Nikolov M,Jans DC,Naumenko N,Aich A,MacVicar T,Linden A,Jakobs S,Urlaub H,Langer T,Rehling P

Mon Feb 04 00:00:00 EST 2019

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

The Journal of cell biology

Richter F,Dennerlein S,Nikolov M,Jans DC,Naumenko N,Aich A,MacVicar T,Linden A,Jakobs S,Urlaub H,Langer T,Rehling P

Mon Feb 04 00:00:00 EST 2019

Photobiomodulation for Global Cerebral Ischemia: Targeting Mitochondrial Dynamics and Functions.

Molecular neurobiology

Wang R,Dong Y,Lu Y,Zhang W,Brann DW,Zhang Q

Fri Mar 01 00:00:00 EST 2019

Photobiomodulation for Global Cerebral Ischemia: Targeting Mitochondrial Dynamics and Functions.

Molecular neurobiology

Wang R,Dong Y,Lu Y,Zhang W,Brann DW,Zhang Q

Fri Mar 01 00:00:00 EST 2019

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.

Biochemical pharmacology

Módis K,Ramanujam VS,Govar AA,Lopez E,Anderson KE,Wang R,Szabo C

Fri Nov 01 00:00:00 EDT 2019

MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress.

Life science alliance

Nagashima S,Takeda K,Ohno N,Ishido S,Aoki M,Saitoh Y,Takada T,Tokuyama T,Sugiura A,Fukuda T,Matsushita N,Inatome R,Yanagi S

Thu Aug 01 00:00:00 EDT 2019

Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.

Journal of agricultural and food chemistry

Wang W,Wang M,Ruan Y,Tan J,Wang H,Yang T,Li J,Zhou Q

Wed Sep 11 00:00:00 EDT 2019

Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.

EBioMedicine

Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D

Tue Jan 01 00:00:00 EST 2019

Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.

EBioMedicine

Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D

Tue Jan 01 00:00:00 EST 2019

Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.

Nature communications

Li SZ,Shu QP,Song Y,Zhang HH,Liu Y,Jin BX,Liuyu TZ,Li C,Huang XC,Du RL,Song W,Zhong B,Zhang XD

Fri Jul 19 00:00:00 EDT 2019

Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.

Nature communications

Li SZ,Shu QP,Song Y,Zhang HH,Liu Y,Jin BX,Liuyu TZ,Li C,Huang XC,Du RL,Song W,Zhong B,Zhang XD

Fri Jul 19 00:00:00 EDT 2019

Mitochondrial localization of PABPN1 in oculopharyngeal muscular dystrophy.

Laboratory investigation; a journal of technical methods and pathology

Doki T,Yamashita S,Wei FY,Hara K,Yamamoto T,Zhang Z,Zhang X,Tawara N,Hino H,Uyama E,Kurashige T,Maruyama H,Tomizawa K,Ando Y

Fri Nov 01 00:00:00 EDT 2019

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation.

Neuron

Smith GA,Lin TH,Sheehan AE,Van der Goes van Naters W,Neukomm LJ,Graves HK,Bis-Brewer DM,Züchner S,Freeman MR

Wed Jul 03 00:00:00 EDT 2019

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.

International journal of molecular sciences

Shah SZA,Zhao D,Taglialatela G,Hussain T,Dong H,Sabir N,Mangi MH,Wu W,Lai M,Zhang X,Duan Y,Wang L,Zhou X,Yang L

Wed Mar 06 00:00:00 EST 2019

Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.

Cells

Sabir N,Hussain T,Liao Y,Wang J,Song Y,Shahid M,Cheng G,Mangi MH,Yao J,Yang L,Zhao D,Zhou X

Sun May 05 00:00:00 EDT 2019

The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice.

Frontiers in immunology

Pandey R,Bakay M,Hain HS,Strenkowski B,Yermakova A,Kushner JA,Orange JS,Hakonarson H

Mon Jan 06 00:00:00 EST 2020

Seneca Valley Virus 2C and 3C^pro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.

Frontiers in microbiology

Liu T,Li X,Wu M,Qin L,Chen H,Qian P

Thu Oct 01 00:00:00 EDT 2020

Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production.

Autophagy

Wang R,Zhu Y,Lin X,Ren C,Zhao J,Wang F,Gao X,Xiao R,Zhao L,Chen H,Jin M,Ma W,Zhou H

Mon Jul 01 00:00:00 EDT 2019

SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells.

Drug metabolism and disposition: the biological fate of chemicals

Hossain MI,Marcus JM,Lee JH,Garcia PL,Gagné JP,Poirier GG,Falany CN,Andrabi SA

Sun Sep 01 00:00:00 EDT 2019

SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells.

Drug metabolism and disposition: the biological fate of chemicals

Hossain MI,Marcus JM,Lee JH,Garcia PL,Gagné JP,Poirier GG,Falany CN,Andrabi SA

Sun Sep 01 00:00:00 EDT 2019

Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo.

eLife

Yambire KF,Rostosky C,Watanabe T,Pacheu-Grau D,Torres-Odio S,Sanchez-Guerrero A,Senderovich O,Meyron-Holtz EG,Milosevic I,Frahm J,West AP,Raimundo N

Tue Dec 03 00:00:00 EST 2019

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.

PLoS genetics

Wang P,Deng J,Dong J,Liu J,Bigio EH,Mesulam M,Wang T,Sun L,Wang L,Lee AY,McGee WA,Chen X,Fushimi K,Zhu L,Wu JY

Wed May 01 00:00:00 EDT 2019

IP₃ receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer.

Nature communications

Bartok A,Weaver D,Golenár T,Nichtova Z,Katona M,Bánsághi S,Alzayady KJ,Thomas VK,Ando H,Mikoshiba K,Joseph SK,Yule DI,Csordás G,Hajnóczky G

Mon Aug 19 00:00:00 EDT 2019

Hydrogen sulfide perturbs mitochondrial bioenergetics and triggers metabolic reprogramming in colon cells.

The Journal of biological chemistry

Libiad M,Vitvitsky V,Bostelaar T,Bak DW,Lee HJ,Sakamoto N,Fearon E,Lyssiotis CA,Weerapana E,Banerjee R

Fri Aug 09 00:00:00 EDT 2019

Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.

Frontiers in immunology

Liao Y,Hussain T,Liu C,Cui Y,Wang J,Yao J,Chen H,Song Y,Sabir N,Hussain M,Zhao D,Zhou X

Tue Jul 21 00:00:00 EDT 2020

Parkin-Dependent Mitophagy is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats.

Cells

He Q,Li Z,Meng C,Wu J,Zhao Y,Zhao J

Wed Aug 14 00:00:00 EDT 2019

Photobiomodulation preconditioning prevents cognitive impairment in a neonatal rat model of hypoxia-ischemia.

Journal of biophotonics

Yang L,Dong Y,Wu C,Li Y,Guo Y,Yang B,Zong X,Hamblin MR,Liu TC,Zhang Q

Sat Jun 01 00:00:00 EDT 2019

Rapid affinity purification of intracellular organelles using a twin strep tag.

Journal of cell science

Xiong J,He J,Xie WP,Hinojosa E,Ambati CSR,Putluri N,Kim HE,Zhu MX,Du G

Fri Dec 13 00:00:00 EST 2019

Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack.

Antiviral research

Martinez-Arroyo O,Gruevska A,Victor VM,González-Polo RA,Yakhine-Diop SMS,Fuentes JM,Esplugues JV,Blas-Garcia A,Apostolova N

Thu Aug 01 00:00:00 EDT 2019

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20.

The Journal of biological chemistry

Zhang C,Wang R,Liu Z,Bunker E,Lee S,Giuntini M,Chapnick D,Liu X

Fri May 03 00:00:00 EDT 2019

Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells.

JCI insight

Zhou Q,Li H,Li Y,Tan M,Fan S,Cao C,Meng F,Zhu L,Zhao L,Guan MX,Jin H,Sun Y

Thu Feb 21 00:00:00 EST 2019

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

Nature

Yoneshiro T,Wang Q,Tajima K,Matsushita M,Maki H,Igarashi K,Dai Z,White PJ,McGarrah RW,Ilkayeva OR,Deleye Y,Oguri Y,Kuroda M,Ikeda K,Li H,Ueno A,Ohishi M,Ishikawa T,Kim K,Chen Y,Sponton CH,Pradhan RN,Majd H,Greiner VJ,Yoneshiro M,Brown Z,Chondronikola M,Takahashi H,Goto T,Kawada T,Sidossis L,Szoka FC,McManus MT,Saito M,Soga T,Kajimura S

Thu Aug 01 00:00:00 EDT 2019

MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.

The EMBO journal

Takeda K,Nagashima S,Shiiba I,Uda A,Tokuyama T,Ito N,Fukuda T,Matsushita N,Ishido S,Iwawaki T,Uehara T,Inatome R,Yanagi S

Thu Aug 01 00:00:00 EDT 2019

Inhibition of lysine-specific demethylase LSD1 induces senescence in Glioblastoma cells through a HIF-1α-dependent pathway.

Biochimica et biophysica acta. Gene regulatory mechanisms

Saccà CD,Gorini F,Ambrosio S,Amente S,Faicchia D,Matarese G,Lania L,Majello B

Wed May 01 00:00:00 EDT 2019

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P₂ and extended synaptotagmins.

Science China. Life sciences

Xiao J,Luo J,Hu A,Xiao T,Li M,Kong Z,Jiang L,Zhou Z,Liao Y,Xie C,Chu B,Miao H,Li B,Shi X,Song BL

Sun Sep 01 00:00:00 EDT 2019

The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.

Cell reports

Wang K,Ma H,Liu H,Ye W,Li Z,Cheng L,Zhang L,Lei Y,Shen L,Zhang F

Tue May 14 00:00:00 EDT 2019

Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.

Cell research

Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC

Wed Aug 01 00:00:00 EDT 2018

Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.

Cell research

Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC

Wed Aug 01 00:00:00 EDT 2018

Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.

Nucleic acids research

Zhang Q,Zhang L,Chen D,He X,Yao S,Zhang Z,Chen Y,Guan MX

Fri Nov 16 00:00:00 EST 2018

Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.

Nucleic acids research

Zhang Q,Zhang L,Chen D,He X,Yao S,Zhang Z,Chen Y,Guan MX

Fri Nov 16 00:00:00 EST 2018

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria.

Journal of innate immunity

Gao X,Chen D,Hu X,Zhou Y,Wang Y,Wu C,Chen J,Wang Y,Pei R,Chen X

Tue Oct 08 00:00:00 EDT 2019

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria.

Journal of innate immunity

Gao X,Chen D,Hu X,Zhou Y,Wang Y,Wu C,Chen J,Wang Y,Pei R,Chen X

Tue Oct 08 00:00:00 EDT 2019

Generation and Characterization of SULT4A1 Mutant Mouse Models.

Drug metabolism and disposition: the biological fate of chemicals

Garcia PL,Hossain MI,Andrabi SA,Falany CN

Mon Jan 01 00:00:00 EST 2018

Generation and Characterization of SULT4A1 Mutant Mouse Models.

Drug metabolism and disposition: the biological fate of chemicals

Garcia PL,Hossain MI,Andrabi SA,Falany CN

Mon Jan 01 00:00:00 EST 2018

Photobiomodulation Therapy Attenuates Hypoxic-Ischemic Injury in a Neonatal Rat Model.

Journal of molecular neuroscience : MN

Tucker LD,Lu Y,Dong Y,Yang L,Li Y,Zhao N,Zhang Q

Wed Aug 01 00:00:00 EDT 2018

Photobiomodulation Therapy Attenuates Hypoxic-Ischemic Injury in a Neonatal Rat Model.

Journal of molecular neuroscience : MN

Tucker LD,Lu Y,Dong Y,Yang L,Li Y,Zhao N,Zhang Q

Wed Aug 01 00:00:00 EDT 2018

CLEC16A regulates splenocyte and NK cell function in part through MEK signaling.

PloS one

Pandey R,Bakay M,Hain HS,Strenkowski B,Elsaqa BZB,Roizen JD,Kushner JA,Orange JS,Hakonarson H

Thu Feb 28 00:00:00 EST 2019

CLEC16A regulates splenocyte and NK cell function in part through MEK signaling.

PloS one

Pandey R,Bakay M,Hain HS,Strenkowski B,Elsaqa BZB,Roizen JD,Kushner JA,Orange JS,Hakonarson H

Thu Feb 28 00:00:00 EST 2019

Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.

Frontiers in molecular neuroscience

Zhang J,Liu L,Xue Y,Ma Y,Liu X,Li Z,Li Z,Liu Y

Wed Oct 20 00:00:00 EDT 2021

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Parkin Modulates ERRα/eNOS Signaling Pathway in Endothelial Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Xia W,Yin J,Zhang S,Guo C,Li Y,Zhang Y,Zhang A,Jia Z,Chen H

Tue Oct 16 00:00:00 EDT 2018

Parkin Modulates ERRα/eNOS Signaling Pathway in Endothelial Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Xia W,Yin J,Zhang S,Guo C,Li Y,Zhang Y,Zhang A,Jia Z,Chen H

Tue Oct 16 00:00:00 EDT 2018

PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.

Cell death & disease

Xiao Y,Zhou Y,Lu Y,Zhou K,Cai W

Wed Feb 07 00:00:00 EST 2018

PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.

Cell death & disease

Xiao Y,Zhou Y,Lu Y,Zhou K,Cai W

Wed Feb 07 00:00:00 EST 2018

Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.

Scientific reports

Yu Z,Ma J,Li X,Liu Y,Li M,Wang L,Zhao M,He H,Zhang Y,Rao Q,Zhao D,Wang Y,Fan L,Li P,Liu Y,Liu F,Zhang F,Ye J,Yan Q,Guo S,Wang Z

Mon Jul 02 00:00:00 EDT 2018

Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.

Scientific reports

Yu Z,Ma J,Li X,Liu Y,Li M,Wang L,Zhao M,He H,Zhang Y,Rao Q,Zhao D,Wang Y,Fan L,Li P,Liu Y,Liu F,Zhang F,Ye J,Yan Q,Guo S,Wang Z

Mon Jul 02 00:00:00 EDT 2018

Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.

Scientific reports

Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J

Mon Feb 19 00:00:00 EST 2018

Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.

Scientific reports

Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J

Mon Feb 19 00:00:00 EST 2018

Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.

Scientific reports

Rodríguez-Hidalgo M,Luna-Sánchez M,Hidalgo-Gutiérrez A,Barriocanal-Casado E,Mascaraque C,Acuña-Castroviejo D,Rivera M,Escames G,López LC

Tue Sep 18 00:00:00 EDT 2018

Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.

Scientific reports

Rodríguez-Hidalgo M,Luna-Sánchez M,Hidalgo-Gutiérrez A,Barriocanal-Casado E,Mascaraque C,Acuña-Castroviejo D,Rivera M,Escames G,López LC

Tue Sep 18 00:00:00 EDT 2018

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 EDT 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 EDT 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 EDT 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 EDT 2017

Autophagy protects auditory hair cells against neomycin-induced damage.

Autophagy

He Z,Guo L,Shu Y,Fang Q,Zhou H,Liu Y,Liu D,Lu L,Zhang X,Ding X,Liu D,Tang M,Kong W,Sha S,Li H,Gao X,Chai R

Tue Jun 04 00:00:00 EDT 2019

Autophagy protects auditory hair cells against neomycin-induced damage.

Autophagy

He Z,Guo L,Shu Y,Fang Q,Zhou H,Liu Y,Liu D,Lu L,Zhang X,Ding X,Liu D,Tang M,Kong W,Sha S,Li H,Gao X,Chai R

Tue Jun 04 00:00:00 EDT 2019

Autophagy protects auditory hair cells against neomycin-induced damage.

Autophagy

He Z,Guo L,Shu Y,Fang Q,Zhou H,Liu Y,Liu D,Lu L,Zhang X,Ding X,Liu D,Tang M,Kong W,Sha S,Li H,Gao X,Chai R

Tue Jun 04 00:00:00 EDT 2019

Autophagy protects auditory hair cells against neomycin-induced damage.

Autophagy

He Z,Guo L,Shu Y,Fang Q,Zhou H,Liu Y,Liu D,Lu L,Zhang X,Ding X,Liu D,Tang M,Kong W,Sha S,Li H,Gao X,Chai R

Tue Jun 04 00:00:00 EDT 2019

Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress.

British journal of pharmacology

Polo M,Alegre F,Moragrega AB,Gibellini L,Marti-Rodrigo A,Blas-Garcia A,Esplugues JV,Apostolova N

Fri Dec 01 00:00:00 EST 2017

Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress.

British journal of pharmacology

Polo M,Alegre F,Moragrega AB,Gibellini L,Marti-Rodrigo A,Blas-Garcia A,Esplugues JV,Apostolova N

Fri Dec 01 00:00:00 EST 2017

Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.

Antioxidants & redox signaling

Liu G,Park SH,Imbesi M,Nathan WJ,Zou X,Zhu Y,Jiang H,Parisiadou L,Gius D

Sat May 20 00:00:00 EDT 2017

Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.

Antioxidants & redox signaling

Liu G,Park SH,Imbesi M,Nathan WJ,Zou X,Zhu Y,Jiang H,Parisiadou L,Gius D

Sat May 20 00:00:00 EDT 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.

Frontiers in physiology

Contino S,Porporato PE,Bird M,Marinangeli C,Opsomer R,Sonveaux P,Bontemps F,Dewachter I,Octave JN,Bertrand L,Stanga S,Kienlen-Campard P

Wed Sep 30 00:00:00 EDT 2020

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.

Frontiers in physiology

Contino S,Porporato PE,Bird M,Marinangeli C,Opsomer R,Sonveaux P,Bontemps F,Dewachter I,Octave JN,Bertrand L,Stanga S,Kienlen-Campard P

Wed Sep 30 00:00:00 EDT 2020

A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis.

Scientific reports

Zhang J,Liu X,Liang X,Lu Y,Zhu L,Fu R,Ji Y,Fan W,Chen J,Lin B,Yuan Y,Jiang P,Zhou X,Guan MX

Tue Jul 18 00:00:00 EDT 2017

A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis.

Scientific reports

Zhang J,Liu X,Liang X,Lu Y,Zhu L,Fu R,Ji Y,Fan W,Chen J,Lin B,Yuan Y,Jiang P,Zhou X,Guan MX

Tue Jul 18 00:00:00 EDT 2017

Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.

Cell death & disease

Sun S,Liu J,Zhao M,Han Y,Chen P,Mo Q,Wang B,Chen G,Fang Y,Tian Y,Zhou J,Ma D,Gao Q,Wu P

Thu Jun 08 00:00:00 EDT 2017

Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.

Cell death & disease

Sun S,Liu J,Zhao M,Han Y,Chen P,Mo Q,Wang B,Chen G,Fang Y,Tian Y,Zhou J,Ma D,Gao Q,Wu P

Thu Jun 08 00:00:00 EDT 2017

The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity.

Molecular neurodegeneration

Ando M,Fiesel FC,Hudec R,Caulfield TR,Ogaki K,Górka-Skoczylas P,Koziorowski D,Friedman A,Chen L,Dawson VL,Dawson TM,Bu G,Ross OA,Wszolek ZK,Springer W

Mon Apr 24 00:00:00 EDT 2017

The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity.

Molecular neurodegeneration

Ando M,Fiesel FC,Hudec R,Caulfield TR,Ogaki K,Górka-Skoczylas P,Koziorowski D,Friedman A,Chen L,Dawson VL,Dawson TM,Bu G,Ross OA,Wszolek ZK,Springer W

Mon Apr 24 00:00:00 EDT 2017

Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.

Oncotarget

Zeng HL,Yang Q,Du H,Li H,Shen Y,Liu T,Chen X,Kamal GM,Guan Q,Cheng L,Wang J,Xu F

Fri Nov 24 00:00:00 EST 2017

Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.

Oncotarget

Zeng HL,Yang Q,Du H,Li H,Shen Y,Liu T,Chen X,Kamal GM,Guan Q,Cheng L,Wang J,Xu F

Fri Nov 24 00:00:00 EST 2017

Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.

Autophagy

Gao J,Li M,Qin S,Zhang T,Jiang S,Hu Y,Deng Y,Zhang C,You D,Li H,Mu D,Zhang Z,Jiang C

Mon Dec 26 00:00:00 EST 2016

Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.

Autophagy

Gao J,Li M,Qin S,Zhang T,Jiang S,Hu Y,Deng Y,Zhang C,You D,Li H,Mu D,Zhang Z,Jiang C

Mon Dec 26 00:00:00 EST 2016

Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.

Cell death and differentiation

Li H,Ruan Y,Zhang K,Jian F,Hu C,Miao L,Gong L,Sun L,Zhang X,Chen S,Chen H,Liu D,Song Z

Tue Mar 01 00:00:00 EST 2016

Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.

Cell death and differentiation

Li H,Ruan Y,Zhang K,Jian F,Hu C,Miao L,Gong L,Sun L,Zhang X,Chen S,Chen H,Liu D,Song Z

Tue Mar 01 00:00:00 EST 2016

Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture.

The international journal of biochemistry & cell biology

Mot AI,Liddell JR,White AR,Crouch PJ

Sat Oct 01 00:00:00 EDT 2016

Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture.

The international journal of biochemistry & cell biology

Mot AI,Liddell JR,White AR,Crouch PJ

Sat Oct 01 00:00:00 EDT 2016

PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration.

Human molecular genetics

Chen Y,Deng J,Wang P,Yang M,Chen X,Zhu L,Liu J,Lu B,Shen Y,Fushimi K,Xu Q,Wu JY

Thu Dec 01 00:00:00 EST 2016

PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration.

Human molecular genetics

Chen Y,Deng J,Wang P,Yang M,Chen X,Zhu L,Liu J,Lu B,Shen Y,Fushimi K,Xu Q,Wu JY

Thu Dec 01 00:00:00 EST 2016

Cross-Talk Between Mitochondrial Fusion and the Hippo Pathway in Controlling Cell Proliferation During Drosophila Development.

Genetics

Deng Q,Guo T,Zhou X,Xi Y,Yang X,Ge W

Mon Aug 01 00:00:00 EDT 2016

Incorporation of VSV-G produces fusogenic plasma membrane vesicles capable of efficient transfer of bioactive macromolecules and mitochondria.

Biomedical microdevices

Lin HP,Zheng DJ,Li YP,Wang N,Chen SJ,Fu YC,Xu WC,Wei CJ

Wed Jun 01 00:00:00 EDT 2016

Incorporation of VSV-G produces fusogenic plasma membrane vesicles capable of efficient transfer of bioactive macromolecules and mitochondria.

Biomedical microdevices

Lin HP,Zheng DJ,Li YP,Wang N,Chen SJ,Fu YC,Xu WC,Wei CJ

Wed Jun 01 00:00:00 EDT 2016

miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1).

Molecular neurodegeneration

Kim J,Fiesel FC,Belmonte KC,Hudec R,Wang WX,Kim C,Nelson PT,Springer W,Kim J

Tue Jul 26 00:00:00 EDT 2016

miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1).

Molecular neurodegeneration

Kim J,Fiesel FC,Belmonte KC,Hudec R,Wang WX,Kim C,Nelson PT,Springer W,Kim J

Tue Jul 26 00:00:00 EDT 2016

Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis.

Oncotarget

Li S,Wang J,Zhou A,Khan FA,Hu L,Zhang S

Tue Aug 30 00:00:00 EDT 2016

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells.

PloS one

Anand R,Strecker V,Urbach J,Wittig I,Reichert AS

Tue Aug 22 00:00:00 EDT 2017

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells.

PloS one

Anand R,Strecker V,Urbach J,Wittig I,Reichert AS

Tue Aug 22 00:00:00 EDT 2017

Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy.

Scientific reports

Wang YH,Wang JQ,Wang Q,Wang Y,Guo C,Chen Q,Chai T,Tang TS

Tue Apr 26 00:00:00 EDT 2016

Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy.

Scientific reports

Wang YH,Wang JQ,Wang Q,Wang Y,Guo C,Chen Q,Chai T,Tang TS

Tue Apr 26 00:00:00 EDT 2016

Tom70 mediates Sendai virus-induced apoptosis on mitochondria.

Journal of virology

Wei B,Cui Y,Huang Y,Liu H,Li L,Li M,Ruan KC,Zhou Q,Wang C

Wed Apr 01 00:00:00 EDT 2015

Tom70 mediates Sendai virus-induced apoptosis on mitochondria.

Journal of virology

Wei B,Cui Y,Huang Y,Liu H,Li L,Li M,Ruan KC,Zhou Q,Wang C

Wed Apr 01 00:00:00 EDT 2015

Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin.

Human mutation

Fiesel FC,Caulfield TR,Moussaud-Lamodière EL,Ogaki K,Dourado DF,Flores SC,Ross OA,Springer W

Sat Aug 01 00:00:00 EDT 2015

Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin.

Human mutation

Fiesel FC,Caulfield TR,Moussaud-Lamodière EL,Ogaki K,Dourado DF,Flores SC,Ross OA,Springer W

Sat Aug 01 00:00:00 EDT 2015

Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.

Acta biochimica et biophysica Sinica

Gao J,Qin S,Jiang C

Wed Jul 01 00:00:00 EDT 2015

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

PLoS genetics

Deng J,Yang M,Chen Y,Chen X,Liu J,Sun S,Cheng H,Li Y,Bigio EH,Mesulam M,Xu Q,Du S,Fushimi K,Zhu L,Wu JY

Tue Sep 01 00:00:00 EDT 2015

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

PLoS genetics

Deng J,Yang M,Chen Y,Chen X,Liu J,Sun S,Cheng H,Li Y,Bigio EH,Mesulam M,Xu Q,Du S,Fushimi K,Zhu L,Wu JY

Tue Sep 01 00:00:00 EDT 2015

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.

Nature communications

Murakawa T,Yamaguchi O,Hashimoto A,Hikoso S,Takeda T,Oka T,Yasui H,Ueda H,Akazawa Y,Nakayama H,Taneike M,Misaka T,Omiya S,Shah AM,Yamamoto A,Nishida K,Ohsumi Y,Okamoto K,Sakata Y,Otsu K

Mon Jul 06 00:00:00 EDT 2015

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.

Nature communications

Murakawa T,Yamaguchi O,Hashimoto A,Hikoso S,Takeda T,Oka T,Yasui H,Ueda H,Akazawa Y,Nakayama H,Taneike M,Misaka T,Omiya S,Shah AM,Yamamoto A,Nishida K,Ohsumi Y,Okamoto K,Sakata Y,Otsu K

Mon Jul 06 00:00:00 EDT 2015

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.

Nature communications

Murakawa T,Yamaguchi O,Hashimoto A,Hikoso S,Takeda T,Oka T,Yasui H,Ueda H,Akazawa Y,Nakayama H,Taneike M,Misaka T,Omiya S,Shah AM,Yamamoto A,Nishida K,Ohsumi Y,Okamoto K,Sakata Y,Otsu K

Mon Jul 06 00:00:00 EDT 2015

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.

Nature communications

Murakawa T,Yamaguchi O,Hashimoto A,Hikoso S,Takeda T,Oka T,Yasui H,Ueda H,Akazawa Y,Nakayama H,Taneike M,Misaka T,Omiya S,Shah AM,Yamamoto A,Nishida K,Ohsumi Y,Okamoto K,Sakata Y,Otsu K

Mon Jul 06 00:00:00 EDT 2015

MicroRNA directly enhances mitochondrial translation during muscle differentiation.

Cell

Zhang X,Zuo X,Yang B,Li Z,Xue Y,Zhou Y,Huang J,Zhao X,Zhou J,Yan Y,Zhang H,Guo P,Sun H,Guo L,Zhang Y,Fu XD

Thu Jul 31 00:00:00 EDT 2014

MicroRNA directly enhances mitochondrial translation during muscle differentiation.

Cell

Zhang X,Zuo X,Yang B,Li Z,Xue Y,Zhou Y,Huang J,Zhao X,Zhou J,Yan Y,Zhang H,Guo P,Sun H,Guo L,Zhang Y,Fu XD

Thu Jul 31 00:00:00 EDT 2014

MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection.

PLoS pathogens

Huang Y,Liu H,Li S,Tang Y,Wei B,Yu H,Wang C

Sat Mar 01 00:00:00 EST 2014

MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection.

PLoS pathogens

Huang Y,Liu H,Li S,Tang Y,Wei B,Yu H,Wang C

Sat Mar 01 00:00:00 EST 2014

MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection.

PLoS pathogens

Huang Y,Liu H,Li S,Tang Y,Wei B,Yu H,Wang C

Sat Mar 01 00:00:00 EST 2014

A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.

Journal of cell science

Fiesel FC,Moussaud-Lamodière EL,Ando M,Springer W

Fri Aug 15 00:00:00 EDT 2014

A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently.

Journal of cell science

Fiesel FC,Moussaud-Lamodière EL,Ando M,Springer W

Fri Aug 15 00:00:00 EDT 2014

Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin.

PLoS computational biology

Caulfield TR,Fiesel FC,Moussaud-Lamodière EL,Dourado DF,Flores SC,Springer W

Sat Nov 01 00:00:00 EDT 2014

Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin.

PLoS computational biology

Caulfield TR,Fiesel FC,Moussaud-Lamodière EL,Dourado DF,Flores SC,Springer W

Sat Nov 01 00:00:00 EDT 2014

Mitochondrial abnormalities in temporal lobe of autistic brain.

Neurobiology of disease

Tang G,Gutierrez Rios P,Kuo SH,Akman HO,Rosoklija G,Tanji K,Dwork A,Schon EA,Dimauro S,Goldman J,Sulzer D

Sat Jun 01 00:00:00 EDT 2013

Mitochondrial abnormalities in temporal lobe of autistic brain.

Neurobiology of disease

Tang G,Gutierrez Rios P,Kuo SH,Akman HO,Rosoklija G,Tanji K,Dwork A,Schon EA,Dimauro S,Goldman J,Sulzer D

Sat Jun 01 00:00:00 EDT 2013

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism.

PloS one

Lai D,Tan CL,Gunaratne J,Quek LS,Nei W,Thierry F,Bellanger S

Mon Jul 14 00:00:00 EDT 2014

Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism.

PloS one

Lai D,Tan CL,Gunaratne J,Quek LS,Nei W,Thierry F,Bellanger S

Mon Jul 14 00:00:00 EDT 2014

UXT-V1 facilitates the formation of MAVS antiviral signalosome on mitochondria.

Journal of immunology (Baltimore, Md. : 1950)

Huang Y,Liu H,Ge R,Zhou Y,Lou X,Wang C

Sun Jan 01 00:00:00 EST 2012

UXT-V1 facilitates the formation of MAVS antiviral signalosome on mitochondria.

Journal of immunology (Baltimore, Md. : 1950)

Huang Y,Liu H,Ge R,Zhou Y,Lou X,Wang C

Sun Jan 01 00:00:00 EST 2012

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.

Cell research

Liu XY,Wei B,Shi HX,Shan YF,Wang C

Wed Sep 01 00:00:00 EDT 2010

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.

Cell research

Liu XY,Wei B,Shi HX,Shan YF,Wang C

Wed Sep 01 00:00:00 EDT 2010

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.

Cell research

Liu XY,Wei B,Shi HX,Shan YF,Wang C

Wed Sep 01 00:00:00 EDT 2010

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.

Cell research

Liu XY,Wei B,Shi HX,Shan YF,Wang C

Wed Sep 01 00:00:00 EDT 2010

Bioinformatics

Protein Aliases: Mitochondrial 20 kDa outer membrane protein; Mitochondrial import receptor subunit TOM20 homolog; outer mitochondrial membrane receptor rTOM20; Outer mitochondrial membrane receptor Tom20; translocase of outer mitochondrial membrane 20 homolog type II

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Gene Aliases: 1810060K07Rik; BB284719; Gm19268; KIAA0016; MAS20; mKIAA0016; MOM19; TOM20; TOMM20

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UniProt ID: (Human) Q15388, (Rat) Q62760, (Mouse) Q9DCC8

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Entrez Gene ID: (Human) 9804, (Rat) 266601, (Mouse) 67952

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Function(s)

protein binding protein channel activity P-P-bond-hydrolysis-driven protein transmembrane transporter activity mitochondrion targeting sequence binding unfolded protein binding primary active transporter

Process(es)

protein targeting to mitochondrion tRNA import into mitochondrion macroautophagy protein import into mitochondrial matrix mitochondrial outer membrane translocase complex assembly protein transmembrane transport protein targeting transport intracellular protein transport protein transport

Performance Guarantee

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TOM20 Polyclonal Antibody

TOM20 Antibody (11802-1-AP) in ICC/IF

Product Details

11802-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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