Invitrogen

VEGF Monoclonal Antibody (VG1)

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (6)
Published Figures (16)

VEGF Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 22

VEGF Antibody (MA1-16629) in ICC/IF

Immunofluorescence analysis of VEGF was performed using DU 145 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with VEGF Monoclonal Antibody (VG1) (Product # MA1-16629) at 1:200 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32766), (1:2000 diluti... View More

VEGF Antibody in Immunohistochemistry (Paraffin) (IHC (P))

VEGF Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Product Details

MA1-16629

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 16 publications 16 publications

Immunohistochemistry (IHC)

View 51 publications 51 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:100

View 5 publications 5 publications

Immunohistochemistry (Frozen) (IHC (F))

1:20-1:100

Immunocytochemistry (ICC/IF)

1:10-1:500

View 3 publications 3 publications

Flow Cytometry (Flow)

Assay-Dependent

ELISA (ELISA)

Assay-Dependent

Product Specifications

Species Reactivity

Dog, Human, Mouse, Pig, Rat

Published species

Camelid, Human, Mouse, Rabbit, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

VG1

Immunogen

Recombinant VEGF protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2212682

Product Specific Information

For IHC, incubate for a period of 30-60 minutes at room temperature.

High temperature treatment of formalin-fixed tissue sections using 1mM EDTA, pH 8.0 must be performed prior to the immunostaining.

Target Information

VEGF (vascular endothelial growth factor) which is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis, and vascular permeability. The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. Studies have shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis. Elevated levels of VEGF is linked to POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) also known as Crow-Fukase syndrome which affects multiple organs in the body.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Morphogenetic events influencing corneal maturation, development, and transparency: Light and electron microscopic study.

Microscopy research and technique

Ibrahim N,Hifny A,Elhanbaly R,El-Desoky SMM,Gaber W

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Immunohistochemistry

Mon May 01 00:00:00 EDT 2023

Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy.

Theranostics

Reddy SK,Ballal AR,Shailaja S,Seetharam RN,Raghu CH,Sankhe R,Pai K,Tender T,Mathew M,Aroor A,Shetty AK,Adiga S,Devi V,Muttigi MS,Upadhya D

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Wed May 10 00:00:00 EDT 2023

Human umbilical cord mesenchymal stem cells-derived exosomal circDLGAP4 promotes angiogenesis after cerebral ischemia-reperfusion injury by regulating miR-320/KLF5 axis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Feng J,He W,Xia J,Huang Q,Yang J,Gu WP,Zhang N,Liu YH

MA1-16629 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to find that exosomal circDLGAP4 negatively regulated miR-320 in HBMECs, which directly bound to KLF5. In addition, the downregulation of miR-320 could reverse the regulatory effect of exosomal shcircDLGAL5 in H/R-treated HBMECs by upregulating KLF5.

Wed Mar 01 00:00:00 EST 2023

l-Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia.

British journal of pharmacology

Man AWC,Zhou Y,Lam UDP,Reifenberg G,Werner A,Habermeier A,Closs EI,Daiber A,Münzel T,Xia N,Li H

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Wed Jun 01 00:00:00 EDT 2022

Characterization of the primo vascular system in rabbit vagina.

Microscopy research and technique

Mustafa FEA,Abdelhafez EA,Abd-Elhafeez HH

MA1-16629 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to characterize primo node as observed on the lymph vessel of rabbit vagina.

Tue Feb 01 00:00:00 EST 2022

Influence of genistein and diadizine on regularity of estrous cycle in cyclic female Wistar rat: interaction with estradiol receptors and vascular endothelial growth factor.

Open veterinary journal

Elsayed DH,Helmy SA,Dessouki AA,El-Nahla AM,Abdelrazek HMA,El-Hak HNG

MA1-16629 was used in Immunohistochemistry-paraffin to investigate the interactions of isoflavones with estrogen receptors alpha (ERα), beta (ERβ), and vascular endothelial growth factor (VEGF) expressions in ovarian and uterine tissues during different stages of the estrous cycle of regular cyclic female Wistar rats.

Tue Jan 03 00:00:00 EST 2023

Characterization of giant neuroendocrine cells in the pregnant New Zealand white rabbit vagina demonstrated by histological, histochemical, and immunohistochemical methods.

Microscopy research and technique

Mustafa FEA

MA1-16629 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to detect the presence of giant neuroendocrine cells in the vagina of the pregnant rabbit.

Sat Oct 01 00:00:00 EDT 2022

The RNA Methyltransferase METTL3 Promotes Endothelial Progenitor Cell Angiogenesis in Mandibular Distraction Osteogenesis via the PI3K/AKT Pathway.

Frontiers in cell and developmental biology

Jiang W,Zhu P,Huang F,Zhao Z,Zhang T,An X,Liao F,Guo L,Liu Y,Zhou N,Huang X

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Fri Nov 19 00:00:00 EST 2021

Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.

Molecular cancer therapeutics

Wang Y,Pandey RN,Roychoudhury K,Milewski D,Kalin TV,Szabo S,Pressey JG,Hegde RS

MA1-16629 was used in Immunohistochemistry to investigate molecular and cellular mechanisms through which EYA3 might promote Ewing sarcoma tumor growth and to determine whether the EYA3 tyrosine phosphatase activity represents a viable therapeutic target.

Sat May 01 00:00:00 EDT 2021

Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.

Molecular cancer therapeutics

Wang Y,Pandey RN,Roychoudhury K,Milewski D,Kalin TV,Szabo S,Pressey JG,Hegde RS

Sat May 01 00:00:00 EDT 2021

An Injectable Fibrin Scaffold Rich in Growth Factors for Skin Repair.

BioMed research international

Shao Z,Lyu C,Teng L,Xie X,Sun J,Zou D,Lu J

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Immunohistochemistry

Tue May 25 00:00:00 EDT 2021

Physiological Effects of Intermittent Passive Exposure to Hypobaric Hypoxia and Cold in Rats.

Frontiers in physiology

Santocildes G,Viscor G,Pagès T,Ramos-Romero S,Torres JL,Torrella JR

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Sat Jun 19 00:00:00 EDT 2021

Physiological Effects of Intermittent Passive Exposure to Hypobaric Hypoxia and Cold in Rats.

Frontiers in physiology

Santocildes G,Viscor G,Pagès T,Ramos-Romero S,Torres JL,Torrella JR

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Sat Jun 19 00:00:00 EDT 2021

MicroRNA-205 mediates endothelial progenitor functions in distraction osteogenesis by targeting the transcription regulator NOTCH2.

Stem cell research & therapy

Jiang W,Zhu P,Zhang T,Liao F,Yu Y,Liu Y,Shen H,Zhao Z,Huang X,Zhou N

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Western Blot

Wed Feb 03 00:00:00 EST 2021

Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis.

Frontiers in pharmacology

Zhang Q,Long J,Li N,Ma X,Zheng L

MA1-16629 was used in Western Blot to suggest that the overexpression of circ_CLASP2 protected HUVEC from HG-induced dysfunction at least partly through the regulation of the miR-140-5p/FBXW7 axis.

Tue Mar 30 00:00:00 EDT 2021

Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis.

Frontiers in pharmacology

Zhang Q,Long J,Li N,Ma X,Zheng L

MA1-16629 was used in Western Blot to suggest that the overexpression of circ_CLASP2 protected HUVEC from HG-induced dysfunction at least partly through the regulation of the miR-140-5p/FBXW7 axis.

Tue Mar 30 00:00:00 EDT 2021

Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas.

Journal of bone oncology

Schoedel K,Miller V,Osei-Hwedieh D,Watters R,Duensing A,John I,Chandran U,Chang A,Soman V,Weiss K

MA1-16629 was used in Immunohistochemistry to study the expression of angiogenesis markers as future treatment targets for dedifferentiated chondrosarcomas.

Sun Aug 01 00:00:00 EDT 2021

Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas.

Journal of bone oncology

Schoedel K,Miller V,Osei-Hwedieh D,Watters R,Duensing A,John I,Chandran U,Chang A,Soman V,Weiss K

MA1-16629 was used in Immunohistochemistry to study the expression of angiogenesis markers as future treatment targets for dedifferentiated chondrosarcomas.

Sun Aug 01 00:00:00 EDT 2021

Effect of soy isoflavones on implantation losses in Wistar rat: implication of progesterone receptors, vascular endothelial growth factor and estradiol receptors alpha.

Iranian journal of veterinary research

Elsayed DH,Abdelrazek HMA,Eltamany DA,Ebaid HM,El-Nahla AM

MA1-16629 was used in Immunohistochemistry to study the implantation losses caused by soy isoflavones.

Thu Apr 14 00:00:00 EDT 2022

Effect of vitamin B₁₂ supplementation on retinal lesions in diabetic rats.

Molecular vision

Reddy SS,Prabhakar YK,Kumar CU,Reddy PY,Reddy GB

MA1-16629 was used in Western Blotting to investigate the impact of dietary supplementation of vitamin B12 on retinal changes in diabetic rats.

Mon May 10 00:00:00 EDT 2021

Effect of vitamin B₁₂ supplementation on retinal lesions in diabetic rats.

Molecular vision

Reddy SS,Prabhakar YK,Kumar CU,Reddy PY,Reddy GB

MA1-16629 was used in Western Blotting to investigate the impact of dietary supplementation of vitamin B12 on retinal changes in diabetic rats.

Mon May 10 00:00:00 EDT 2021

An updated investigation on the dromedary camel cerebellum (Camelus dromedarius) with special insight into the distribution of calcium-binding proteins.

Scientific reports

Attaai AH,Noreldin AE,Abdel-Maksoud FM,Hussein MT

MA1-16629 was used in Immunohistochemistry (Paraffin) to display a complete map for the neurochemical organization of CaBP expression and distribution by different cells in the camel cerebellum.

Thu Dec 03 00:00:00 EST 2020

An updated investigation on the dromedary camel cerebellum (Camelus dromedarius) with special insight into the distribution of calcium-binding proteins.

Scientific reports

Attaai AH,Noreldin AE,Abdel-Maksoud FM,Hussein MT

MA1-16629 was used in Immunohistochemistry (Paraffin) to display a complete map for the neurochemical organization of CaBP expression and distribution by different cells in the camel cerebellum.

Thu Dec 03 00:00:00 EST 2020

Contractile Activity Is Necessary to Trigger Intermittent Hypobaric Hypoxia-Induced Fiber Size and Vascular Adaptations in Skeletal Muscle.

Frontiers in physiology

Rizo-Roca D,Bonet JB,Ínal B,Ríos-Kristjánsson JG,Pagès T,Viscor G,Torrella JR

MA1-16629 was used in Western Blotting to study the effects of intermittent hypobaric hypoxia on different myofiber morphofunctional parameters and investigate whether contractile activity is required to elicit hypoxia-induced adaptations in trained rats.

Wed Sep 30 00:00:00 EDT 2020

Contractile Activity Is Necessary to Trigger Intermittent Hypobaric Hypoxia-Induced Fiber Size and Vascular Adaptations in Skeletal Muscle.

Frontiers in physiology

Rizo-Roca D,Bonet JB,Ínal B,Ríos-Kristjánsson JG,Pagès T,Viscor G,Torrella JR

Wed Sep 30 00:00:00 EDT 2020

Topical Loperamide-Encapsulated Liposomal Gel Increases the Severity of Inflammation and Accelerates Disease Progression in the Adjuvant-Induced Model of Experimental Rheumatoid Arthritis.

Frontiers in pharmacology

Hua S,Dias TH,Pepperall DG,Yang Y

Published figure using VEGF monoclonal antibody (Product # MA1-16629) in Immunohistochemistry

Wed Sep 30 00:00:00 EDT 2020

The Eyes Absent Proteins in Developmental and Pathological Angiogenesis.

The American journal of pathology

Wang Y,Tadjuidje E,Pandey RN,Stefater JA,Smith LE,Lang RA,Hegde RS

MA1-16629 was used in immunocytochemistry to study proteins absent in the eyes during pathological and developmental angiogenesis

Tue Mar 01 00:00:00 EST 2016

Comparative study of membranes induced by PMMA or silicone in rats, and influence of external radiotherapy.

Acta biomaterialia

de Monès E,Schlaubitz S,Oliveira H,d'Elbée JM,Bareille R,Bourget C,Couraud L,Fricain JC

MA1-16629 was used in western blot to investigate the benefits of replacing a PMMA spacer with a semi-flexible medical grade silicone spacer for long bone defect reconstruction

Mon Jun 01 00:00:00 EDT 2015

Gastric cancer in young vs old Romanian patients: immunoprofile with emphasis on maspin and mena protein reactivity.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Gurzu S,Kadar Z,Sugimura H,Bara T,Bara T,Halmaciu I,Jung I

MA1-16629 was used in immunohistochemistry - paraffin section to use Romanian patients with gastric carcinomas and compare the demographic, clinical, and immunohistochemical aspects of each cancer

Sun Mar 01 00:00:00 EST 2015

Oxygen-induced retinopathy in mice with retinal photoreceptor cell degeneration.

Life sciences

Zhang Q,Zhang ZM

MA1-16629 was used in western blot to study retinal neovascularization during oxygen-induced retinopathy in mice with photoreceptor cell degeneration

Fri Apr 25 00:00:00 EDT 2014

Thymic epithelial tumors express vascular endothelial growth factors and their receptors as potential targets of antiangiogenic therapy: a tissue micro array-based multicenter study.

Lung cancer (Amsterdam, Netherlands)

Lattanzio R,La Sorda R,Facciolo F,Sioletic S,Lauriola L,Martucci R,Gallo E,Palmieri G,Evoli A,Alessandrini G,Ruco L,Rendina EA,Truini M,Chiarle R,Barreca A,Pich A,Ascani S,Remotti D,Tunesi G,Granone P,Ratto GB,Puma F,Pescarmona E,Piantelli M,Marino M,Carlini S,Cerasoli V,Corzani F,Melis E,Filippetti M,Canalini P,Palestro G,Lalle M,Ruffini E,Ceribelli A,Rinaldi M

MA1-16629 was used in immunohistochemistry to study the immunohistochemical expression of VEGF and VEGFR isoforms in patients with thymic epithelial tumors

Fri Aug 01 00:00:00 EDT 2014

The effect of lipoic acid on wound healing in a full thickness uterine injury model in rats.

Journal of molecular histology

Micili SC,Goker A,Sayin O,Akokay P,Ergur BU

MA1-16629 was used in immunohistochemistry to use a rat full thickness uterine injury model to study the beneficial effects of lipoic acid on wound healing

Sat Jun 01 00:00:00 EDT 2013

Paraneoplastic symptoms: cachexia, polycythemia, and hypercalcemia are, respectively, related to vascular endothelial growth factor (VEGF) expression in renal clear cell carcinoma.

Urologic oncology

Ding GX,Feng CC,Song NH,Fang ZJ,Xia GW,Jiang HW,Hua LX,Ding Q

MA1-16629 was used in immunohistochemistry to study the relationship between expression of VEGF and the development of paraneoplastic symptoms in patients with renal clear cell carcinoma

Fri Nov 01 00:00:00 EDT 2013

The efficacy of bevacizumab, sorafenib, and retinoic acid on rat endometriosis model.

Reproductive sciences (Thousand Oaks, Calif.)

Ozer H,Boztosun A,Açmaz G,Atilgan R,Akkar OB,Kosar MI

MA1-16629 was used in immunohistochemistry to compare the therapeutic effects of bevacizumab, sorafenib and nicotinic acid in a rat model of endometriosis

Tue Jan 01 00:00:00 EST 2013

Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits.

PloS one

Karimian E,Tamm C,Chagin AS,Samuelsson K,Kjartansdóttir KR,Ohlsson C,Sävendahl L

MA1-16629 was used in immunohistochemistry to study the potential mechanisms involved in the delayed growth plate fusion and increased longitudonal bome growth observed in female rabbits treated with resveratrol

Thu Apr 24 00:00:00 EDT 2014

Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review.

PloS one

Gurzu S,Ciortea D,Munteanu T,Kezdi-Zaharia I,Jung I

MA1-16629 was used in immunohistochemistry to develop a hypothesis of Kaposi sarcoma histogenesis based on a case and literature review

Tue Apr 01 00:00:00 EDT 2014

The relevance of the intrinsic subtype to the clinicopathological features and biomarkers in Japanese breast cancer patients.

World journal of surgical oncology

Tamaki M,Kamio T,Kameoka S,Kojimahara N,Nishikawa T

MA1-16629 was used in immunohistochemistry to study the effect of breast cancer intrinsic subtype on cliniopathological and biomarker profiles in Japanese patients

Mon Nov 18 00:00:00 EST 2013

The impact of KRAS mutations on VEGF-A production and tumour vascular network.

BMC cancer

Figueras A,Arbos MA,Quiles MT,Viñals F,Germà JR,Capellà G

MA1-16629 was used in western blot to study the differential effects on the production of VEGF-A and tumor vasculature development of codon 12 and codon 13 KRAS mutations

Mon Mar 18 00:00:00 EDT 2013

Temporal and pharmacological characterization of angiostatin release and generation by human platelets: implications for endothelial cell migration.

PloS one

Radziwon-Balicka A,Moncada de la Rosa C,Zielnik B,Doroszko A,Jurasz P

MA1-16629 was used in immunocytochemistry to study the production and release of angiostatin by human platelets

Tue Sep 24 00:00:00 EDT 2013

Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.

Scientific reports

Qiu SQ,Wei XL,Huang WH,Wu MY,Qin YS,Li YK,Zhang GJ

MA1-16629 was used in immunohistochemistry - paraffin section to report the clinicopathological features of 9 breast malignant fibrous histiocytoma patients

Fri Feb 14 00:00:00 EST 2014

Paraneoplastic hormones: parathyroid hormone-related protein (PTHrP) and erythropoietin (EPO) are related to vascular endothelial growth factor (VEGF) expression in clear cell renal cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Feng CC,Ding GX,Song NH,Li X,Wu Z,Jiang HW,Ding Q

MA1-16629 was used in immunohistochemistry to study the expression of PTHrP, EPO and VEGF in clear cell renal cell carcinoma and their relationships with tumor grade

Sun Dec 01 00:00:00 EST 2013

Biological and demographic profile of meningiomas in a cohort of Egyptian patients: impact on tumor recurrence.

TheScientificWorldJournal

Abdelzaher E,El Deeb NM,Gowil AG,Yehya A

MA1-16629 was used in immunohistochemistry to study the relationship between meningioma biological and demographic profiles and disease recurrence in Egyptian patients

Mon Jun 16 00:00:00 EDT 2014

The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets.

Thrombosis research

Nylander M,Osman A,Ramström S,Aklint E,Larsson A,Lindahl TL

MA1-16629 was used in immunocytochemistry to study the production and secretion of PAI-1 by human platelets and the roles played by the the PAR1 and PAR4 thrombin receptors

Sun Apr 01 00:00:00 EDT 2012

Prediction of the shrinking rate of uterine leiomyoma nodules using needle biopsy specimens.

Fertility and sterility

Kasai M,Ichimura T,Kawamura N,Sumikura T,Matsuda M,Asano C,Sumi T,Ishiko O

MA1-16629 was used in immunohistochemistry to study the relationship between the shrinking of uterine leiomyoma nodules and the expression of ER, PR and VEGF following menopause or pharmacological treatment

Wed Aug 01 00:00:00 EDT 2012

Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers.

International journal of cancer

Yadav VR,Prasad S,Sung B,Gelovani JG,Guha S,Krishnan S,Aggarwal BB

MA1-16629 was used in immunohistochemistry to study the mechanisms underlying the inhibitory effects of boswellic acid on human colorectal cancer growth and metasatsis in an orthotopic murine model

Tue May 01 00:00:00 EDT 2012

Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model.

Pharmaceutical research

Shukla S,MacLennan GT,Fu P,Gupta S

MA1-16629 was used in western blot to study the effects of the plant flavone apigenin on IGF-1 signaling, angiogenesis, and metastasis in a murine prostate cancer model

Fri Jun 01 00:00:00 EDT 2012

Lipoxin A4 inhibits the development of endometriosis in mice: the role of anti-inflammation and anti-angiogenesis.

American journal of reproductive immunology (New York, N.Y. : 1989)

Xu Z,Zhao F,Lin F,Chen J,Huang Y

MA1-16629 was used in immunohistochemistry to study the anti-inflammatory and anti-angiogenic mechanisms by which lipoxin A4 inhibits endometriosis in a murine model

Fri Jun 01 00:00:00 EDT 2012

Bronchial carcinoid tumors metastatic to the sella turcica and review of the literature.

Pituitary

Moshkin O,Rotondo F,Scheithauer BW,Soares M,Coire C,Smyth HS,Goth M,Horvath E,Kovacs K

MA1-16629 was used in immunohistochemistry to report on a case of bronchial carcinoid tumors metastatic to the sella turcica

Fri Jun 01 00:00:00 EDT 2012

Immunohistochemical study of the angiogenetic network of VEGF, HIF1α, VEGFR-2 and endothelial nitric oxide synthase (eNOS) in human breast cancer.

Pathology oncology research : POR

Kafousi M,Vrekoussis T,Tsentelierou E,Pavlakis K,Navrozoglou I,Dousias V,Sanidas E,Tsiftsis D,Georgoulias V,Stathopoulos EN

MA1-16629 was used in immunohistochemistry to study the expression of VEGF, VEGFR-2, HIF1-alpha and eNOS in invasive ductal carcinoma

Sun Jan 01 00:00:00 EST 2012

Pulmonary artery sarcoma with angiosarcoma phenotype mimicking pleomorphic malignant fibrous histiocytoma: a case report.

Diagnostic pathology

Bohn OL,de León EA,Lezama O,Rios-Luna NP,Sánchez-Sosa S,Llombart-Bosch A

MA1-16629 was used in immunohistochemistry to report on a case of pulmonary artery sarcoma

Wed Nov 07 00:00:00 EST 2012

VEGFR1 expression is related to lymph node metastasis and serum VEGF may be a marker of progression in the follow-up of patients with differentiated thyroid carcinoma.

European journal of endocrinology

Karaca Z,Tanriverdi F,Unluhizarci K,Ozturk F,Gokahmetoglu S,Elbuken G,Cakir I,Bayram F,Kelestimur F

MA1-16629 was used in immunohistochemistry to investigate the roles of VEGFR1 and VEGF during lymph node metastasis and differentiated thyroid carcinoma

Tue Feb 01 00:00:00 EST 2011

Effect of phototherapy on growth factor levels in neonatal rat skin.

Journal of pediatric surgery

Soyer T,Ayva S,Aliefendioğlu D,Aktuna Z,Aslan MK,Senyücel MF,Cakmak M

MA1-16629 was used in immunohistochemistry to study the effects of phototherapy on the levels of growth factors involved in wound healing in neonatal rat skin

Tue Nov 01 00:00:00 EDT 2011

Immunolocalization of VEGF, VEGF receptors, EGF-R and Ki-67 in leiomyoma, cellular leiomyoma and leiomyosarcoma.

Acta histochemica

Sanci M,Dikis C,Inan S,Turkoz E,Dicle N,Ispahi C

MA1-16629 was used in immunohistochemistry to study the role of VEGF, VEGF receptors, EGF receptor and Ki-67 in leiomyosarcoma

Sun May 01 00:00:00 EDT 2011

The effect of antivascular endothelial growth factor on the development of adhesion formation in laparotomized rats: experimental study.

Gastroenterology research and practice

Basbug M,Bulbuller N,Camci C,Ayten R,Aygen E,Ozercan IH,Arikanoglu Z,Akbulut S

MA1-16629 was used in immunohistochemistry to study the effect of an anti-VEGF monoclonal antibody on the formation of adhesions in the rat cecal abrasion model

Thu Nov 10 00:00:00 EST 2011

Angiogenesis in the progression of breast ductal proliferations.

International journal of surgical pathology

Carpenter PM,Chen WP,Mendez A,McLaren CE,Su MY

MA1-16629 was used in immunohistochemistry to study the role of angiogenesis in the progression of breast ductal carcinomas

Wed Jun 01 00:00:00 EDT 2011

Serum and pulmonary vascular endothelial growth factor/receptors and haemodynamic measurements in cyanotic congenital heart disease with decreased pulmonary blood flow.

Cardiology in the young

Tolunay I,Tunaoglu S,Akyürek N,Halid V,Olgunturk R,Kula S

MA1-16629 was used in immunohistochemistry to study levels of VEGF and VEGFR in the serum and lungs of patients with cyanotic congenital heart disease

Thu Dec 01 00:00:00 EST 2011

Vascular endothelial growth factor (VEGF) enhances gastric carcinoma invasiveness via integrin alpha(v)beta6.

Cancer letters

Zhao R,Liu XQ,Wu XP,Liu YF,Zhang ZY,Yang GY,Guo S,Niu J,Wang JY,Xu KS

MA1-16629 was used in immunohistochemistry to investigate the effect of vascular endothelial growth factor on gastric carcinoma invasiveness and its mechanism

Thu Jan 28 00:00:00 EST 2010

Influence of 670 nm low-level laser therapy on mast cells and vascular response of cutaneous injuries.

Journal of photochemistry and photobiology. B, Biology

Pereira MC,de Pinho CB,Medrado AR,Andrade Zde A,Reis SR

MA1-16629 was used in immunohistochemistry to study the effect laser therapy on the inflammatory and vascular responses of cutaneous wounds

Mon Mar 08 00:00:00 EST 2010

Prevention of ovarian hyperstimulation syndrome in a rat model: efficacy comparison between cabergoline and meloxicam.

Acta obstetricia et gynecologica Scandinavica

Saylan A,Arioz DT,Koken T,Dilek H,Saylan F,Yilmazer M

MA1-16629 was used in immunohistochemistry to compare the effectiveness between cabergoline and meloxicam in the prevention of ovarian hyperstimulation syndrome

Sat May 01 00:00:00 EDT 2010

Anti-human vascular endothelial growth factor (VEGF) antibody selection for immunohistochemical staining of proliferating blood vessels.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

van der Loos CM,Meijer-Jorna LB,Broekmans ME,Ploegmakers HP,Teeling P,de Boer OJ,van der Wal AC

MA1-16629 was used in immunohistochemistry to evaluate suitable vascular endothelial growth factor antibodies for the detection of proliferating blood vessels

Mon Feb 01 00:00:00 EST 2010

Vascular endothelial growth factor: a possible mediator of endothelial activation in acute respiratory distress syndrome.

Minerva anestesiologica

Azamfirei L,Gurzu S,Solomon R,Copotoiu R,Copotoiu S,Jung I,Tilinca M,Branzaniuc K,Corneci D,Szederjesi J,Kovacs J

MA1-16629 was used in immunohistochemistry to study the potential role of VEGF in mediating endothelial activation in acute respiratory distress syndrome

Sun Aug 01 00:00:00 EDT 2010

Molecular biomarkers for advanced renal cell carcinoma: implications for prognosis and therapy.

Urologic oncology

Kim HS,Kim WS,Park SH,Jung CW,Choi HY,Lee HM,Jeon SS,Ha H,Hwang IG,Lee S,Lim HY

MA1-16629 was used in immunohistochemistry to identify reliable predictive biomarkers for patients with metastatic renal cell carcinomas

Mon Jun 14 00:00:00 EDT 2010

Maspin, VEGF and p53 expression in small biopsies of primary advanced lung cancer and relationship with clinicopathologic parameters.

Pathology oncology research : POR

Bircan A,Bircan S,Kapucuoglu N,Songur N,Ozturk O,Akkaya A

MA1-16629 was used in immunohistochemistry to compare expression of Maspin, VEGF, and p53 between carcinomas

Wed Dec 01 00:00:00 EST 2010

Evaluation of relationship between HIF-1alpha immunoreactivity and stage, grade, angiogenic profile and proliferative index in bladder urothelial carcinomas.

International urology and nephrology

Deniz H,Karakök M,Yagci F,Güldür ME

MA1-16629 was used in immunohistochemistry to study the relationship between HIF-1alpha expression and various prognostic parameters in bladder urothelial carcinomas

Mon Mar 01 00:00:00 EST 2010

Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice.

American journal of physiology. Renal physiology

Zhang H,Schin M,Saha J,Burke K,Holzman LB,Filipiak W,Saunders T,Xiang M,Heilig CW,Brosius FC

MA1-16629 was used in western blot to investigate the effect of the overexpression of GLUT1 in podocytes on the mesangial matrix expansion in rodent diabetic nephropathy

Thu Jul 01 00:00:00 EDT 2010

Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Dawson MA,Opat SS,Taouk Y,Donovan M,Zammit M,Monaghan K,Horvath N,Roberts AW,Prince HM,Hertzberg M,McLean CA,Spencer A

MA1-16629 was used in immunohistochemistry - paraffin section to investigate the parameters for the identification of multiple myeloma patients suitable for bortezomib therapy

Thu Jan 15 00:00:00 EST 2009

Bevacizumab and breast cancer: current therapeutic progress and future perspectives.

Expert review of anticancer therapy

Yang SX

MA1-16629 was used in immunohistochemistry to evaluate the efficacy of bevacizumab treatment for breast cancer

Tue Dec 01 00:00:00 EST 2009

The differences between the endothelial area marked with CD31 and CD105 in colorectal carcinomas by computer-assisted morphometrical analysis.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Jung I,Gurzu S,Raica M,Cîmpean AM,Szentirmay Z

MA1-16629 was used in immunohistochemistry to compare the CD31 and CD105 endothelial areas in colorectal carcinomas by computer-assisted morphometrical analysis

Fri Sep 18 00:00:00 EDT 2009

Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Schneider BP,Wang M,Radovich M,Sledge GW,Badve S,Thor A,Flockhart DA,Hancock B,Davidson N,Gralow J,Dickler M,Perez EA,Cobleigh M,Shenkier T,Edgerton S,Miller KD

MA1-16629 was used in immunohistochemistry to investigate the prognostic significance of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms in breast cancer treatment

Wed Oct 01 00:00:00 EDT 2008

Neoangiogenesis and expression of hypoxia-inducible factor 1alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas.

Gynecologic oncology

Ozbudak IH,Karaveli S,Simsek T,Erdogan G,Pestereli E

MA1-16629 was used in immunohistochemistry to study the expression of HIF-1alpha, VEGF and GLUT-1 in endometrioid type endometrium adenocarcinomas

Sat Mar 01 00:00:00 EST 2008

Vitreous fluid of db/db mice exhibits alterations in angiogenic and metabolic factors consistent with early diabetic retinopathy.

Ophthalmic research

Cohen MP,Hud E,Shea E,Shearman CW

MA1-16629 was used in western blot to study whether angiogenic and metabolic factors in vitreous fluid of db/db mice reflect early diabetic retinopathy

Tue Jan 15 00:00:00 EST 2008

Vascular endothelial growth factor expression and vascularity in renal allograft biopsies.

Transplantation proceedings

Sarioğlu S,Celik A,Erşen A,Uçer I,Sağlam F,Camsari T,Gülay H

MA1-16629 was used in immunohistochemistry to investigate the relationship between vascular endothelial growth factor expression and the pathology in renal allograft biopsies

Thu May 01 00:00:00 EDT 2008

The expression of cytoskeleton regulatory protein Mena in colorectal lesions.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Gurzu S,Jung I,Prantner I,Ember I,Pávai Z,Mezei T

MA1-16629 was used in immunohistochemistry to investigate the expression of mammalian actin regulatory protein Ena in colorectal lesions

Thu Dec 11 00:00:00 EST 2008

Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress.

Archives of medical research

Yülek F,Or M,Ozoğul C,Isik AC,Ari N,Stefek M,Bauer V,Karasu C

MA1-16629 was used in immunohistochemistry to investigate the therapeautical benefits of stobadine and vitamin E in diabetes-induced retinal abnormalities

Sun Jul 01 00:00:00 EDT 2007

Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma.

World journal of gastroenterology

Bangoura G,Liu ZS,Qian Q,Jiang CQ,Yang GF,Jing S

MA1-16629 was used in immunohistochemistry to investigate the role of the HIF-2alpha/EPAS1 in hepatocellular carcinoma

Thu Jun 21 00:00:00 EDT 2007

Angiogenesis in nodal B cell lymphomas: a high throughput study.

Journal of clinical pathology

Tzankov A,Heiss S,Ebner S,Sterlacci W,Schaefer G,Augustin F,Fiegl M,Dirnhofer S

MA1-16629 was used in immunohistochemistry to study angiogenesis in B cell lymphomas

Tue May 01 00:00:00 EDT 2007

Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival.

Oncology

Cabuk D,Basaran G,Celikel C,Dane F,Yumuk PF,Iyikesici MS,Ekenel M,Turhal NS

MA1-16629 was used in immunohistochemistry to evaluate the prognostic markers for early-stage gastric tumors

Wed Jan 02 00:00:00 EST 2008

Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma.

Urology

Phuoc NB,Ehara H,Gotoh T,Nakano M,Yokoi S,Deguchi T,Hirose Y

MA1-16629 was used in immunohistochemistry to identify prognostic markers for clear cell renal cell carcinoma

Tue May 01 00:00:00 EDT 2007

Evaluation of the prognostic role of a panel of biomarkers in stage IB-IIIA non-small cell lung cancer patients.

Anticancer research

Timotheadou E,Skarlos DV,Samantas E,Papadopoulos S,Murray S,Skrickova J,Christodoulou C,Papakostantinou C,Pectasides D,Papakostas P,Kaplanova J,Vrettou E,Karina M,Kosmidis P,Fountzilas G

MA1-16629 was used in immunohistochemistry to investigate the prognostic biomarkers in stage IB-IIIA non-small cell lung cancer

Thu Feb 28 00:00:00 EST 2008

Effects of finasteride on the vascular surface density, number of microvessels and vascular endothelial growth factor expression of the rat prostate.

International urology and nephrology

Canda AE,Mungan MU,Yilmaz O,Yorukoglu K,Tuzel E,Kirkali Z

MA1-16629 was used in immunohistochemistry to study the effects of a 5-alpha reductase inhibitor on vascularity and VEGF expression in the rat prostate

Mon Mar 05 00:00:00 EST 2007

Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: correlations with prognostic parameters.

Journal of experimental & clinical cancer research : CR

Bolat F,Kayaselcuk F,Nursal TZ,Yagmurdur MC,Bal N,Demirhan B

MA1-16629 was used in immunohistochemistry to study the relationship between microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors

Fri Sep 01 00:00:00 EDT 2006

PGE1 analog alprostadil induces VEGF and eNOS expression in endothelial cells.

American journal of physiology. Heart and circulatory physiology

Haider DG,Bucek RA,Giurgea AG,Maurer G,Glogar H,Minar E,Wolzt M,Mehrabi MR,Baghestanian M

MA1-16629 was used in western blot to study the role of the PGE1 analog alprostadil in inducing VEGF and eNOS expression in endothelial cells

Tue Nov 01 00:00:00 EST 2005

Bioinformatics

Protein Aliases: L-VEGF; MGC70609; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor 165b; vascular endothelial growth factor 188; Vascular endothelial growth factor A; Vascular endothelial growth factor A, long form; vascular endothelial growth factor A121; vascular endothelial growth factor A165; Vascular permeability factor; Vasculotropin; VEGF; VEGF-A; VEGF1; VEGFMGC70609; VPF; VPF ant

View more View less

Gene Aliases: MVCD1; VEGF; VEGF-A; VEGF164; VEGFA; VPF

View more View less

UniProt ID: (Human) H3BLW7, (Dog) Q9MYV3, (Pig) P49151, (Rat) P16612, (Mouse) Q00731

View more View less

Entrez Gene ID: (Human) 7422, (Dog) 403802, (Pig) 397157, (Rat) 83785, (Mouse) 22339

View more View less

Function(s)

fibronectin binding cytokine activity platelet-derived growth factor receptor binding vascular endothelial growth factor receptor binding protein binding growth factor activity heparin binding chemoattractant activity identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 1 binding vascular endothelial growth factor receptor 2 binding protein heterodimerization activity receptor agonist activity extracellular matrix binding receptor binding neuropilin binding growth factor

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

VEGF Monoclonal Antibody (VG1)

VEGF Antibody (MA1-16629) in ICC/IF

Product Details

MA1-16629

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!