Product References
Muscle fibre transition and transcriptional changes of horse skeletal muscles during traditional Mongolian endurance training.
Equine veterinary journal
Bou T,Ding W,Ren X,Liu H,Gong W,Jia Z,Zhang X,Dugarjaviin M,Bai D
Mon Jan 01 00:00:00 EST 2024
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Gut pathogens
Tian Z,Khan AI,Rehman AU,Deng T,Ma C,Wang L
Mon Jan 09 00:00:00 EST 2023
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao L,Sun Y,Zhang X,Ma D,Xie A,Wang E,Cheng L,Liu S
Thu Jun 01 00:00:00 EDT 2023
An enzyme-instructed self-assembly system induces tumor acidosis via sequential-dual effect for cancer selective therapy.
Acta biomaterialia
Zhang H,Wang Z,Gao T,Wang Z,Ren C,Liu J
Sat Jul 01 00:00:00 EDT 2023
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Toxics
Liang C,Jiang Q,Liu Z,Yang J,Zhang J,Zhang S,Xin W
Thu May 11 00:00:00 EDT 2023
Therapeutic role of Artemether in the prevention of hepatic steatosis through miR-34a-5p/PPARα pathway.
Drug development research
Chen L,Yu S,Hong S,Lin X,Zhu X,Cao X,Li Y,Xiao H
Sat Apr 01 00:00:00 EDT 2023
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
ACS applied materials & interfaces
Yi T,Qian J,Ye Y,Zhang H,Jin X,Wang M,Yang Z,Zhang W,Wen L,Zhang Y
Wed Jan 11 00:00:00 EST 2023
The Mechanosensitive Ion Channel PIEZO1 in Intestinal Epithelial Cells Mediates Inflammation through the NOD-Like Receptor 3 Pathway in Crohn's Disease.
Inflammatory bowel diseases
Liu Q,Wang D,Yang X,Ma F,Han W,Hu J,Mei Q
Thu Jan 05 00:00:00 EST 2023
Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication.
Viruses
Ramnani B,Powell S,Shetty AG,Manivannan P,Hibbard BR,Leaman DW,Malathi K
Tue Feb 07 00:00:00 EST 2023
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Experimental dermatology
Tian Y,Ma J,Wang M,Yi X,Guo S,Wang H,Zhang H,Wang H,Yang Y,Zhang B,Du J,Shi Q,Gao T,Li C,Guo W
Sun Oct 01 00:00:00 EDT 2023
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
Oxidative medicine and cellular longevity
Gao R,Wu Y,Yang Q,Chen L,Chen J,Wang B,Liu Z,Jin J,Li J,Wu G
Wed Feb 15 00:00:00 EST 2023
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
BMC complementary medicine and therapies
Cui Y,Zhang F,Xu W,Li Z,Zou J,Gao P,Hu J
Fri Jun 02 00:00:00 EDT 2023
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Acta histochemica
Wang F,Yi J,Chen Y,Bai X,Lu C,Feng S,Zhou X
Tue Aug 01 00:00:00 EDT 2023
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Journal of medical virology
Jia X,Zhang M,Wang H,Cheng C,Li Q,Li Y,Kong L,Lan X,Wang Y,Liang X,Yuan S,Wang Y,Xu A
Wed Mar 01 00:00:00 EST 2023
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Molecular medicine reports
Xiao S,Zhou Y,Gao H,Yang D
Sun Jan 01 00:00:00 EST 2023
Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus.
Biomedicines
Huang S,Tan YQ,Zhou G
Mon Mar 20 00:00:00 EDT 2023
Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.
Journal of innate immunity
He F,Qiu Y,Wu X,Xia Y,Yang L,Wu C,Li P,Zhang R,Fang R,Li N,Peng Y
Tue Dec 26 00:00:00 EST 2023
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
Autophagy
Wang SM,Wu HE,Yasui Y,Geva M,Hayden M,Maurice T,Cozzolino M,Su TP
Sun Jan 01 00:00:00 EST 2023
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Cellular signalling
Chen J,Liu F,Wu J,Yang Y,He J,Wu F,Yang K,Li J,Jiang Z,Jiang Z
Thu Jun 01 00:00:00 EDT 2023
NONO regulates B-cell development and B-cell receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Y,Cui D,Huang M,Zheng Y,Zheng B,Chen L,Chen Q
Sat Apr 01 00:00:00 EDT 2023
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Journal of virology
Tang N,Chen P,Zhao C,Liu P,Tan L,Song C,Qiu X,Liao Y,Liu X,Luo T,Sun Y,Ding C
Thu Mar 30 00:00:00 EDT 2023
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration.
The American journal of Chinese medicine
Yang CG,Mao XL,Wu JF,An X,Cao JJ,Zhang XY,Li M,Zhang FF
Fri Mar 31 00:00:00 EDT 2023
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Cell biology international
Bin Y,Deng W,Hu H,Zeng Q,Chen J,Xu Y,Dai Y,Liao A,Xiao W
Wed Mar 01 00:00:00 EST 2023
RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.
Antiviral research
Yao Y,Sun H,Chen Y,Tian L,Huang D,Liu C,Zhou Y,Wang Y,Wen Z,Yang B,Chen X,Pei R
Sun Jan 01 00:00:00 EST 2023
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
Acta diabetologica
Wang X,Yu S,Liu W,Lv P,Zhao L,Wang Y,Fu C,Meng L,Yang Q,Wang X,Huang Y,Zuo Z,Liu X
Mon May 01 00:00:00 EDT 2023
Identification and characterization of novel carboxyl ester lipase gene variants in patients with different subtypes of diabetes.
BMJ open diabetes research & care
Wu H,Shu M,Liu C,Zhao W,Li Q,Song Y,Zhang T,Chen X,Shi Y,Shi P,Fang L,Wang R,Xu C
Sun Jan 01 00:00:00 EST 2023
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.
Biological research
Qin Y,Zhou Y,Wang K,Gu J,Xiong Z,Zhang W,Chen Y
Fri Apr 21 00:00:00 EDT 2023
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors.
Emerging microbes & infections
Xia S,Wang L,Jiao F,Yu X,Xu W,Huang Z,Li X,Wang Q,Zhu Y,Man Q,Jiang S,Lu L
Fri Dec 01 00:00:00 EST 2023
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang L,Sun L,Wang L,Wang J,Wang D,Jiang J,Zhang J,Zhou Q
Sat Apr 01 00:00:00 EDT 2023
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
International journal of molecular sciences
Lai K,Song C,Gao M,Deng Y,Lu Z,Li N,Geng Q
Tue Mar 07 00:00:00 EST 2023
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Bioengineering & translational medicine
Zhu Z,Li X,Wang X,Zuo X,Ma Y,Gao X,Liang Z,Zhang Z,Song Z,Ding T,Ju C,Li P,Li K,Zhang J,Quan H,Wang Z,Hu X
Mon May 01 00:00:00 EDT 2023
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Journal of experimental & clinical cancer research : CR
Wei W,Zhang ZY,Shi B,Cai Y,Zhang HS,Sun CL,Fei YF,Zhong W,Zhang S,Wang C,He B,Jiang GM,Wang H
Tue Jun 20 00:00:00 EDT 2023
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
ACS omega
Feng C,Liu Y,Zhang BY,Zhang H,Shan FY,Li TQ,Zhao ZN,Wang XX,Zhang XY
Tue Jun 13 00:00:00 EDT 2023
Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.
BMC oral health
Su W,Li J,Jiang L,Lei L,Li H
Wed Feb 15 00:00:00 EST 2023
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li T,Zhang L,Lu T,Zhu T,Feng C,Gao N,Liu F,Yu J,Chen K,Zhong J,Tang Q,Zhang Q,Deng X,Ren J,Zeng J,Zhou H,Zhu J
Sat Apr 01 00:00:00 EDT 2023
The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression.
Microbiology spectrum
Tao Q,Zhu L,Xu L,Yang Y,Zhang Y,Liu Z,Xu T,Wen J,Deng L,Zhou Y,Xu Z
Tue Mar 28 00:00:00 EDT 2023
High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation.
Journal of affective disorders
Zou L,Tian Y,Wang Y,Chen D,Lu X,Zeng Z,Chen Z,Lin C,Liang Y
Fri Apr 14 00:00:00 EDT 2023
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells.
Cell death & disease
Li Q,Kong F,Cong R,Ma J,Wang C,Ma X
Fri Mar 03 00:00:00 EST 2023
Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.
Communications biology
Xiong Y,Cheng Q,Li Y,Han Y,Sun X,Liu L
Sat Apr 15 00:00:00 EDT 2023
Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway.
International journal of biological macromolecules
Zou YF,Li CY,Fu YP,JiZe XP,Zhao YZ,Peng X,Wang JY,Yin ZQ,Li YP,Song X,Li LX,Zhao XH,Feng B,Huang C,Ye G,Tang HQ,Chen J,Li R,Chen XF,Tian ML
Sat Jul 01 00:00:00 EDT 2023
The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.
Scientific reports
Watanabe N,Bando H,Murakoshi F,Sakurai R,Kabir MHB,Fukuda Y,Kato K
Thu Jan 19 00:00:00 EST 2023
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
BMC complementary medicine and therapies
Cai W,Sun B,Song C,Liu F,Wu Z,Liu Z
Fri Apr 14 00:00:00 EDT 2023
Repetitive Transcranial Magnetic Stimulation Improves Depression-like Behavior in Rats by Promoting Neural Stem Cell Proliferation and Differentiation.
Neuroscience
Jiang C,Zheng S,Chen T,Li W,Zhang C,Gu S,Ren H,Song J,Zhang Z
Tue Aug 01 00:00:00 EDT 2023
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Oxidative medicine and cellular longevity
Wan H,Cai Y,Xiao L,Ling Y,Ge L,Mo S,Xie Q,Peng S,Zhou B,Zeng X,Chen X
Tue Jan 23 00:00:00 EST 2024
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Life sciences
Ge Y,Hu D,Xi Y,Wang H,Xia T,Chen J,Pu X,Xiao H
Sat Jul 15 00:00:00 EDT 2023
Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules.
International immunopharmacology
Wu Y,Song X,Li P,Wang Z,Zhao Z,Zhang T
Mon May 01 00:00:00 EDT 2023
Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in vitro.
Theriogenology
Bai H,Kawahara M,Takahashi M
Wed Mar 01 00:00:00 EST 2023
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
The International journal of neuroscience
Wu GM,Du CP,Xu Y
Fri Dec 01 00:00:00 EST 2023
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
Bioscience trends
Wang Z,Shen J,Chen C,Wen T,Li C
Mon May 15 00:00:00 EDT 2023
Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide.
Evidence-based complementary and alternative medicine : eCAM
Zhang X,Zhang W,Chen X,Cai Y
Sat Feb 04 00:00:00 EST 2023
Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
Journal of medical virology
Tu W,Liu J,Qian F,Zhu L,Li M,Zheng H,Zhu C
Wed Mar 01 00:00:00 EST 2023
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Stem cell reviews and reports
Liu D,Li X,Zeng B,Zhao Q,Chen H,Zhang Y,Chen Y,Wang J,Xing HR
Sun Jan 01 00:00:00 EST 2023
CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.
International journal of molecular sciences
Pang B,Araki A,Zhou L,Takebayashi H,Harada T,Kadota K
Fri Mar 10 00:00:00 EST 2023
Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis.
Molecular medicine (Cambridge, Mass.)
Feng Y,Lu J,Peng X,Ge Y,Zhang R,Li H
Wed Jan 18 00:00:00 EST 2023
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li T,Bai H,Yang L,Hao W,Wei S,Yan P
Tue Dec 20 00:00:00 EST 2022
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Oncology reports
Ye S,Li S,Qin L,Zheng W,Liu B,Li X,Ren Z,Zhao H,Hu X,Ye N,Li G
Wed Mar 01 00:00:00 EST 2023
Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling.
Translational oncology
Geng H,Feng C,Sun Z,Fan X,Xie Y,Gu J,Fan L,Liu G,Li C,Thorne RF,Zhang XD,Li X,Liu X
Sun Jan 01 00:00:00 EST 2023
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
iScience
Li Y,Zhang L,Mao M,He L,Wang T,Pan Y,Zhao X,Li Z,Mu X,Qian Y,Qiu J
Fri May 19 00:00:00 EDT 2023
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
International journal of biological macromolecules
Yu WQ,Wang XL,Ji HH,Miao M,Zhang BH,Li H,Zhang ZY,Ji CF,Guo SD
Thu Jun 01 00:00:00 EDT 2023
10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling.
Drug design, development and therapy
Liang Y,Wu G,Luo T,Xie H,Zuo Q,Huang P,Li H,Chen L,Lu H,Chen Q
Wed Feb 01 00:00:00 EST 2023
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhang L,Zhang X,Che D,Zeng L,Zhang Y,Nan K,Zhang X,Zhang H,Guo Z
Sun Jan 01 00:00:00 EST 2023
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
Experimental and therapeutic medicine
Zeng X,Deng X,Ni Y,Bi H,Jiang M,Wang D,Dong P,Xiao Y,Jiang M
Sat Apr 01 00:00:00 EDT 2023
Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology.
Journal of orthopaedic surgery and research
Zhu F,Li W,Wang L,Dai B,Liu Z,Wu H,Deng T
Mon Jan 09 00:00:00 EST 2023
Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.
Frontiers in endocrinology
Hu R,Huang Y,Song Y,Wu X,Song K,Huang G,Zhang M,Dong H
Tue Apr 04 00:00:00 EDT 2023
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
iScience
Xue T,Zhao S,Zhang H,Tang T,Zheng L,Jing J,Ge X,Ma R,Ma J,Ren X,Jueraitetibaike K,Guo Z,Chen L,Yao B
Fri Mar 17 00:00:00 EDT 2023
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.
Science China. Life sciences
Zhang M,Zhang B,Wang X,Song J,Tong M,Dong Z,Xu J,Liu M,Jiang Y,Wang N,Wang Y,Du Z,Liu Y,Zhang R,Xu C
Sat Apr 01 00:00:00 EDT 2023
Elevated nuclear TDP-43 induces constitutive exon skipping.
bioRxiv : the preprint server for biology
Carmen-Orozco RP,Tsao W,Ye Y,Sinha IR,Chang K,Trinh V,Chung W,Bowden K,Troncoso JC,Blackshaw S,Hayes LR,Sun S,Wong PC,Ling JP
Fri May 12 00:00:00 EDT 2023
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Discover. Oncology
Wang C,Liu T,Wang J,Cheng C,Zhang Z,Zhang J,Huang H,Li Y
Sat Jun 03 00:00:00 EDT 2023
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Current research in food science
Gao H,Yin C,Li C,Li Y,Shi D,Fan X,Yao F,Wu W,Li J
Sun Jun 04 00:00:00 EDT 2023
Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.
Neuromolecular medicine
Qi Y,Zhang Z,Li Y,Zhao G,Huang J,Zhang Y,Xue J,Tang X
Fri Sep 01 00:00:00 EDT 2023
Microglia activation mediates circadian rhythm disruption-induced cognitive impairment in mice.
Journal of neuroimmunology
Meng D,Yang M,Zhang H,Zhang L,Song H,Liu Y,Zeng Y,Yang B,Wang X,Chen Y,Liu R
Thu Jun 15 00:00:00 EDT 2023
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Journal of proteome research
Gao X,Lian Q,Guan B,Liu QY,Meng M,Chen Y,Jin J,Li H,Liu X,Sun Z,Liu L,He QY,Zhang G
Fri Apr 07 00:00:00 EDT 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 EDT 2023
N6-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Cell death and differentiation
Gao Z,Li C,Sun H,Bian Y,Cui Z,Wang N,Wang Z,Yang Y,Liu Z,He Z,Li B,Li F,Li Z,Wang L,Zhang D,Yang L,Xu Z,Li X,Xu H
Wed Feb 01 00:00:00 EST 2023
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.
Experimental & molecular medicine
Yan B,Li X,Peng M,Zuo Y,Wang Y,Liu P,Ren W,Jin X
Thu Jun 01 00:00:00 EDT 2023
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Placenta
Yuan D,Guo T,Qian H,Jin C,Ge H,Zhao Y,Zhu D,Lin M,Wang H,Yu H
Sun Jan 01 00:00:00 EST 2023
miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice.
Neuroscience bulletin
Ke X,Deng M,Wu Z,Yu H,Yu D,Li H,Lu Y,Shu K,Pei L
Wed Feb 01 00:00:00 EST 2023
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhao Z,Du JF,Wang QL,Qiu FN,Chen XY,Liu FJ,Li P,Jiang Y,Li HJ
Thu Jun 01 00:00:00 EDT 2023
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhao Z,Du JF,Wang QL,Qiu FN,Chen XY,Liu FJ,Li P,Jiang Y,Li HJ
Thu Jun 01 00:00:00 EDT 2023
Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou N,Wang Y,Zhang Z,Feng W,Liu T,Cao Y,Zhang J,Zhang B,Zheng X,Li K
Thu Jun 01 00:00:00 EDT 2023
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Cell death & disease
Wang Y,Wang Y,Liu W,Ding L,Zhang X,Wang B,Tong Z,Yue X,Li C,Xu L,Wu Z,Liang X,Ma C,Gao L
Mon Feb 20 00:00:00 EST 2023
Ponicidin Induces Apoptosis of Murine Melanoma by Inhibiting the NF-κB Signaling Pathway.
Biological & pharmaceutical bulletin
Wang L,Lou X,Wang D,Lu K,Zhang S,Cheng B
Fri Jun 02 00:00:00 EDT 2023
Potential targets and mechanisms of photobiomodulation for spinal cord injury.
Neural regeneration research
Ju C,Ma YG,Zuo XS,Wang XK,Song ZW,Zhang ZH,Zhu ZJ,Li X,Liang ZW,Ding T,Wang Z,Hu XY
Tue Aug 01 00:00:00 EDT 2023
Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer.
International journal of biological sciences
Chen YM,Xu W,Liu Y,Zhang JH,Yang YY,Wang ZW,Sun DJ,Li H,Liu B,Chen LX
Wed May 24 00:00:00 EDT 2023
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.
The Journal of clinical investigation
Huang C,Zhao S,Yang Y,Guo T,Ke H,Mi X,Qin Y,Chen ZJ,Zhao S
Wed Mar 01 00:00:00 EST 2023
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5.
The Journal of biological chemistry
Choi EB,Vodnala M,Saini P,Anugula S,Zerbato M,Ho JJ,Wang J,Ho Sui SJ,Yoon J,Roels M,Inouye C,Fong YW
Wed Mar 01 00:00:00 EST 2023
CircRNA-02191 regulating unsaturated fatty acid synthesis by adsorbing miR-145 to enhance CD36 expression in bovine mammary gland.
International journal of biological macromolecules
Chen Z,Wang Y,Wang K,Zhang Z,Han M,Li G,Zhang B,Yang Y,Loor JJ,Yang Z,Zhong F,Dai R,Wang M
Mon Jul 31 00:00:00 EDT 2023
In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody.
Journal of cancer research and clinical oncology
Zhu M,Zhang J,Yang M,Zhang H,Xu T,Kan F,Zhang X,Zhang S,Yin Y,Yu F
Fri Sep 01 00:00:00 EDT 2023
Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma.
Molecular biology reports
Yousefi Z,Sharifzadeh S,Zare F,Eskandari N
Wed Feb 01 00:00:00 EST 2023
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.
Chinese medicine
An Y,Dai H,Duan Y,Cheng L,Shi L,He C,Wang C,Lv Y,Li H,Zhang H,Huang Y,Fu W,Sun W,Zhao B
Fri May 05 00:00:00 EDT 2023
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.
International immunopharmacology
Ren M,Chen J,Xu H,Li W,Wang T,Chi Z,Lin Y,Zhang A,Chen G,Wang X,Sun X,Liang G,Wang J,Luo W
Sat Jul 01 00:00:00 EDT 2023
Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lin Z,Huang K,Guo H,Jia M,Sun Q,Chen X,Wu J,Yao Q,Zhang P,Vakal S,Zou Z,Gao H,Ci L,Chen J,Guo W
Mon May 01 00:00:00 EDT 2023
SARS-CoV-2 Omicron XBB subvariants exhibit enhanced fusogenicity and substantial immune evasion in elderly population, but high sensitivity to pan-coronavirus fusion inhibitors.
Journal of medical virology
Xia S,Jiao F,Wang L,Yu X,Lu T,Fu Y,Huang Z,Li X,Huang J,Wang Q,Man Q,Xiong L,Jiang S,Lu L
Wed Mar 01 00:00:00 EST 2023
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2.
Neurochemical research
Yang J,Guo Q,Wang L,Yu S
Wed Feb 01 00:00:00 EST 2023
Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility.
Cell and tissue research
Mirshahvaladi S,Topraggaleh TR,Bucak MN,Rahimizadeh P,Shahverdi A
Thu Jun 01 00:00:00 EDT 2023
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Journal of periodontology
Huang X,Wang X,Ma L,Wang H,Peng Y,Liu H,Xiao J,Cao Z
Wed Feb 01 00:00:00 EST 2023
Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.
Microbiology spectrum
Yu J,Liu T,Guo Q,Wang Z,Chen Y,Dong Y
Tue Jan 31 00:00:00 EST 2023
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang W,Zuo J,Liu M,Su Y,Guo B,Hou J,Xing Q,Peng Y,Fang L,Cao Y,Shan J,Sun R,Zhao J,Wang J
Sun Jan 01 00:00:00 EST 2023
cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway.
Journal of immunology (Baltimore, Md. : 1950)
Shen X,Sun C,Cheng Y,Ma D,Sun Y,Lin Y,Zhao Y,Yang M,Jing W,Cui X,Han L
Sat Apr 15 00:00:00 EDT 2023
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Journal of ethnopharmacology
Wang Y,Zhang J,Zhang B,Lu M,Ma J,Liu Z,Huang J,Ma J,Yang X,Wang F,Tang X
Fri Sep 15 00:00:00 EDT 2023
Nutrient-dependent regulation of β-cell proinsulin content.
The Journal of biological chemistry
Xu X,Arunagiri A,Alam M,Haataja L,Evans CR,Zhao I,Castro-Gutierrez R,Russ HA,Demangel C,Qi L,Tsai B,Liu M,Arvan P
Sat Jul 01 00:00:00 EDT 2023
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.
Oxidative medicine and cellular longevity
Li R,Liu R,Chen L,Wang G,Qin L,Yu Z,Wan Z
Wed Feb 01 00:00:00 EST 2023
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Journal of applied oral science : revista FOB
Chen Y,Liu Y,Li H,Huna R,Tan X,Li N,Zhang Y,Jiao X,Liu M
Fri Feb 10 00:00:00 EST 2023
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Molecular medicine (Cambridge, Mass.)
Chen Y,Liu X,Li L,He X,Zheng F,Zhang Y,Gao H,Jin Z,Wu D,Wang Q,Tao H,Zhao Y,Liu W,Zou L
Mon Feb 06 00:00:00 EST 2023
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Journal of extracellular vesicles
Chen Y,Ou Z,Pang M,Tao Z,Zheng X,Huang Z,Wen D,Li Q,Zhou R,Chen P,Situ B,Sheng C,Huang Y,Yue X,Zheng L,Huang L
Mon May 01 00:00:00 EDT 2023
Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents.
The Journal of organic chemistry
Fang H,Li Y,Zhang L,Yan ZH,Ma K,Peng C,Huang W,Zhan G
Fri Jun 02 00:00:00 EDT 2023
PSKH1 affects proliferation and invasion of osteosarcoma cells via the p38/MAPK signaling pathway.
Oncology letters
Zhu X,Jiang C,Wang Z,Zhu X,Yuan F,Yang Y
Sat Apr 01 00:00:00 EDT 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 EST 2023
Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
International journal of biological sciences
Chen H,Ye C,Wu C,Zhang J,Xu L,Wang X,Xu C,Zhang J,Guo Y,Yao Q
Tue May 09 00:00:00 EDT 2023
Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase.
British journal of pharmacology
Kong W,Sun X,Yu S,Liu P,Zheng X,Zhang J,Zhu L,Jiang T,Jin M,Gao J,Fan X,Liu X,Liu L
Sat Jul 01 00:00:00 EDT 2023
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Brain sciences
Li X,Zhou R,Peng H,Peng J,Li Q,Mei M
Fri Feb 03 00:00:00 EST 2023
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Biochemical and biophysical research communications
Jiang Z,Sun H,Miao J,Sheng Q,Xu J,Gao Z,Zhang X,Song Y,Chen K
Sun Jan 15 00:00:00 EST 2023
Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis.
Molecular medicine reports
Yang ZJ,Liu R,Han XJ,Qiu CL,Dong GL,Liu ZQ,Liu LH,Luo Y,Jiang LP
Sat Apr 01 00:00:00 EDT 2023
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
Cell research
Lin Z,Zhao S,Li X,Miao Z,Cao J,Chen Y,Shi Z,Zhang J,Wang D,Chen S,Wang L,Gu A,Chen F,Yang T,Sun K,Han Y,Xie L,Chen H,Ji Y
Sat Jul 01 00:00:00 EDT 2023
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
Neural regeneration research
Li ZY,Zhou AF,Li G,Zhou LY,Pu PM,Zhu K,Zheng Z,Wang YJ,Liang QQ,Yao M,Cui XJ
Wed Mar 01 00:00:00 EST 2023
Qingre Huazhuo Jiangsuan Decoction promotes autophagy by inhibiting PI3K/AKT/mTOR signaling pathway to relieve acute gouty arthritis.
Journal of ethnopharmacology
Liu P,Xu Y,Ye J,Tan J,Hou J,Wang Y,Li J,Cui W,Wang S,Zhao Q
Fri Feb 10 00:00:00 EST 2023
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
International journal of molecular sciences
Ma M,Luan X,Zheng H,Wang X,Wang S,Shen T,Ren D
Thu Jan 05 00:00:00 EST 2023
ARID1B blocks methionine-stimulated mTOR activation to inhibit milk fat and protein synthesis in and proliferation of mouse mammary epithelial cells.
The Journal of nutritional biochemistry
Lin G,Qi H,Guo X,Wang W,Zhang M,Gao X
Sat Apr 01 00:00:00 EDT 2023
Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.
Frontiers in microbiology
Li F,Fu X,Luo X,Lin Q,Liang H,Niu Y,Liu L,Li N
Tue Apr 18 00:00:00 EDT 2023
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.
Cell death & disease
Ren L,Meng L,Gao J,Lu M,Guo C,Li Y,Rong Z,Ye Y
Fri Jan 20 00:00:00 EST 2023
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
International journal of molecular sciences
Yang A,Yan S,Yin Y,Chen C,Tang X,Ran M,Chen B
Fri Mar 24 00:00:00 EDT 2023
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.
Journal of agricultural and food chemistry
Zhang H,Chen F,Xu S,Zhang W,Li R,Yao Q,Zhao Y,Zhu Z,Chen L
Wed Feb 08 00:00:00 EST 2023
Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway.
Molecular and cellular biochemistry
Chen Q,Che C,Yang S,Ding P,Si M,Yang G
Wed Feb 01 00:00:00 EST 2023
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
Journal of extracellular vesicles
Wang X,Xu F,Kou H,Zheng Y,Yang J,Xu Z,Fang Y,Sun W,Zhu S,Jiang Q,Wei X,Xu Y
Sat Jul 01 00:00:00 EDT 2023
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.
Journal of neuroinflammation
Wang Y,Sun J,Zhu K,Wang D,Zhao X,Zhang H,Wu S,Wang Y,Wang J
Sat Mar 25 00:00:00 EDT 2023
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Translational oncology
Hua Q,Lu Y,Wang D,Da J,Peng W,Sun G,Gu K,Wang H,Zhu Y
Wed Feb 01 00:00:00 EST 2023
Metabolism-related lncRNAs signature to predict the prognosis of colon adenocarcinoma.
Cancer medicine
Sun Y,Liu B,Xiao B,Jiang X,Xiang JJ,Xie J,Hu XM
Wed Mar 01 00:00:00 EST 2023
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Journal of cellular and molecular medicine
Wang Y,Gan Y,Dong Y,Zhou J,Zhu E,Yuan H,Li X,Wang B
Sat Apr 01 00:00:00 EDT 2023
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Frontiers in immunology
Guo J,Zhou M,Zhao M,Li S,Fang Z,Li A,Zhang M
Tue May 02 00:00:00 EDT 2023
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Autophagy
Zheng W,Chen Q,Liu H,Zeng L,Zhou Y,Liu X,Bai Y,Zhang J,Pan Y,Shao C
Wed Mar 01 00:00:00 EST 2023
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Journal of periodontal research
Ding X,Hou Y,Liu X,Li X,Liu X,Deng Y,Cao N,Yu W
Wed Feb 01 00:00:00 EST 2023
A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice.
Cell reports
Sanford JD,Jin A,Grois GA,Zhang Y
Tue Jan 31 00:00:00 EST 2023
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Molecular carcinogenesis
Wu W,Chen X,Liu X,Bao HJ,Li QH,Xian JY,Lu BF,Zhao Y,Chen S
Sat Apr 01 00:00:00 EDT 2023
Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.
Phytotherapy research : PTR
Yang Y,Chen R,Che Y,Yao X,Fang M,Wang Y,Zhou D,Li N,Hou Y
Fri Sep 01 00:00:00 EDT 2023
Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker.
Computational and mathematical methods in medicine
Zou K,Gao P,Xu X,Zhang W,Zeng Z
Mon Jan 30 00:00:00 EST 2023
KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.
Cell death & disease
Li J,Yu D,He C,Yu Q,Huo Z,Zhang Y,Zhang S
Sat Jul 01 00:00:00 EDT 2023
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Journal of translational medicine
Lin Z,Lv Z,Liu X,Huang K
Mon Apr 10 00:00:00 EDT 2023
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Journal of chemical neuroanatomy
Wu B,Gan A,Wang R,Lin F,Yan T,Jia Y
Sat Jul 01 00:00:00 EDT 2023
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ye Z,Xiong Y,Peng W,Wei W,Huang L,Yue J,Zhang C,Lin G,Huang F,Zhang L,Zheng S,Yue J
Wed Feb 01 00:00:00 EST 2023
EFEMP1 is a potential biomarker of choroid thickness change in myopia.
Frontiers in neuroscience
Shi WQ,Wan T,Li B,Li T,Zhou XD
Fri Mar 10 00:00:00 EST 2023
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
The American journal of pathology
Chen X,Song QL,Wang JY,Ji R,Li ZH,Cao ML,Mu XF,Guo DY,Zhang Y,Yang J
Tue Aug 01 00:00:00 EDT 2023
Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.
Journal of inorganic biochemistry
Liu J,Wu Y,Yang G,Liu Z,Liu X
Wed Feb 01 00:00:00 EST 2023
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Cell & bioscience
Gu G,Zhu B,Ren J,Song X,Fan B,Ding H,Shang J,Wu H,Li J,Wang H,Li J,Wei Z,Feng S
Sat Feb 04 00:00:00 EST 2023
Taurochenodeoxycholic acid inhibits intestinal epithelial cell proliferation and induces apoptosis independent of the farnesoid X receptor.
Food & function
Liu Y,Niu K,Wang R,Liang X,Lin C,Wu X,Zhai Z
Tue Jun 06 00:00:00 EDT 2023
A Prevascularized Sinus Tract on the Liver Surface for Islet Transplantation.
Transplantation
Li F,Lv Y,Li X,Yang Z,Guo T,Zhang J
Sun Jan 01 00:00:00 EST 2023
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
The Journal of clinical investigation
Zheng C,Wei Y,Zhang P,Xu L,Zhang Z,Lin K,Hou J,Lv X,Ding Y,Chiu Y,Jain A,Islam N,Malovannaya A,Wu Y,Ding F,Xu H,Sun M,Chen X,Chen Y
Wed Mar 01 00:00:00 EST 2023
Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO3 Stimulation.
Oxidative medicine and cellular longevity
Zhang S,Qiu Y,Feng Y,Zhang Y,Li Y,Wang B,Wei H,Chen X,Shen L,Li W,Zheng L,Zhang Y
Tue Jan 31 00:00:00 EST 2023
ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.
Cell biology international
Guo X,Qi H,Lin G,Yu J,Zhang M,Gao X
Thu Jun 01 00:00:00 EDT 2023
Cannabinoid type 2 receptor activation inhibits MPP+-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
Molecular biology reports
Wang M,Liu M,Ma Z
Mon May 01 00:00:00 EDT 2023
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Journal of ethnopharmacology
Fang X,Zhang X,Zhang Y,Zhang X,Shan M,Guan S,Qiu Z,Zhu D,Luo H
Wed Mar 01 00:00:00 EST 2023
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
British journal of haematology
Zhang J,Shi F,Liu X,Wu X,Hu C,Guo J,Yang Q,Xia J,He Y,An G,Qiu L,Feng X,Zhou W
Mon May 01 00:00:00 EDT 2023
Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
International journal of molecular sciences
Liu H,Ma H,Zeng X,Wu C,Acharya S,Sudan SK,Zhang X
Mon Jun 12 00:00:00 EDT 2023
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Neuroscience bulletin
Zhang Y,Zhao X,Guo C,Zhang Y,Zeng F,Yin Q,Li Z,Shao L,Zhou D,Liu L
Fri Sep 01 00:00:00 EDT 2023
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
Zhang X,Wu Q,Zheng W,Liu C,Huang L,Zuo X,Xiao W,Han X,Ye H,Wang W,Yang L,Zhu Y
Wed Mar 01 00:00:00 EST 2023
Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.
Theranostics
Li X,Chen X,Gong S,Zhao J,Yao C,Zhu H,Xiao R,Qin Y,Li R,Sun N,Li X,Dong F,Zhao T,Pan Y,Yang J
Tue Apr 18 00:00:00 EDT 2023
Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.
Nutrients
Zhang Y,Zhu Z,Sun L,Yin W,Liang Y,Chen H,Bi Y,Zhai W,Yin Y,Zhang W
Tue Apr 11 00:00:00 EDT 2023
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Dalton transactions (Cambridge, England : 2003)
Zheng H,Hu C,Quan Y,Ye X,Shi X,Guo Z,Wang X
Tue Jun 06 00:00:00 EDT 2023
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
International journal of radiation oncology, biology, physics
Wen R,Zhou L,Jiang S,Fan H,Zheng K,Yu Y,Gao X,Hao L,Lou Z,Yu G,Yang F,Zhang W
Fri Sep 01 00:00:00 EDT 2023
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Journal of cellular biochemistry
Yu X,Teng Q,Bao K,Chudhary M,Qi H,Zhou W,Che H,Liu J,Ren X,Kong L
Wed Mar 01 00:00:00 EST 2023
Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug.
Journal of nanobiotechnology
Song J,Cheng M,Xie Y,Li K,Zang X
Thu Mar 16 00:00:00 EDT 2023
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
The journal of gene medicine
Shao Q,Jiang C,Zhang Q,Liu J,Jin B,Zhao M,Xia Y
Fri Sep 01 00:00:00 EDT 2023
Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma.
Disease markers
Tan J,Shen P,Yang X,Cai W,Liao H
Tue Mar 07 00:00:00 EST 2023
Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Niu XQ,Li DD,Bao YJ,Yang Q,Liu YK,Lu F,Yan JZ,Yin XH,Li C
Sun Jan 01 00:00:00 EST 2023
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wu M,Jin Q,Xu X,Fan J,Chen W,Miao M,Gu R,Zhang S,Guo Y,Huang S,Zhang Y,Zhang A,Jia Z
Fri Sep 01 00:00:00 EDT 2023
Structure of Semliki Forest virus in complex with its receptor VLDLR.
Cell
Cao D,Ma B,Cao Z,Zhang X,Xiang Y
Thu May 11 00:00:00 EDT 2023
Profiling the metabolome of uterine fluid for early detection of ovarian cancer.
Cell reports. Medicine
Wang P,Ma J,Li W,Wang Q,Xiao Y,Jiang Y,Gu X,Wu Y,Dong S,Guo H,Li M
Tue Jun 20 00:00:00 EDT 2023
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Scientific reports
Hu A,Liu J,Wang Y,Zhang M,Guo Y,Qin Y,Liu T,Men Y,Chen Q,Liu T
Fri Jan 13 00:00:00 EST 2023
Orai1 is an Entotic Ca2+ Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lee AR,Park CY
Mon May 01 00:00:00 EDT 2023
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
Acta biomaterialia
Sun L,Liu Y,Yang N,Ye X,Liu Z,Wu J,Zhou M,Zhong W,Cao M,Zhang J,Mequanint K,Xing M,Liao W
Wed Mar 01 00:00:00 EST 2023
d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice.
International immunopharmacology
Jiang Q,Wei B,You M,Zhou X
Mon May 01 00:00:00 EDT 2023
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Molecular medicine reports
Luo Y,Chen P,Yang L,Duan X
Sun Jan 01 00:00:00 EST 2023
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Nephrology (Carlton, Vic.)
Liu Z,Xiang H,Deng Q,Fu W,Li Y,Yu Z,Qiu Y,Mei Z,Xu L
Thu Jun 01 00:00:00 EDT 2023
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Nature communications
Wu J,Bu D,Wang H,Shen D,Chong D,Zhang T,Tao W,Zhao M,Zhao Y,Fang L,Li P,Xue B,Li CJ
Fri Mar 24 00:00:00 EDT 2023
ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy.
Science advances
Gong X,Wang Y,Tang Y,Wang Y,Zhang M,Li M,Zhang Y,Pan L
Wed Mar 01 00:00:00 EST 2023
C9ORF72 suppresses JAK-STAT mediated inflammation.
iScience
Pang W,Hu F
Fri May 19 00:00:00 EDT 2023
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
World journal of surgical oncology
Cheng X,Jia X,Wang C,Zhou S,Chen J,Chen L,Chen J
Tue Mar 28 00:00:00 EDT 2023
Reciprocal FGF19-GLI2 signaling induces epithelial-to-mesenchymal transition to promote lung squamous cell carcinoma metastasis.
Cellular oncology (Dordrecht)
Zhang Y,Wu T,Wang Y,Chen Z,Chen J,Lu S,Xia W
Sat Apr 01 00:00:00 EDT 2023
SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.
Journal of medical virology
Deng J,Zheng Y,Zheng SN,Nan ML,Han L,Zhang J,Jin Y,Pan JA,Gao C,Wang PH
Wed Mar 01 00:00:00 EST 2023
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Developmental cell
Geng J,Khaket TP,Pan J,Li W,Zhang Y,Ping Y,Cobos Sillero MI,Lu B
Mon Apr 10 00:00:00 EDT 2023
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.
Aging and disease
Lin X,Xiang QY,Li S,Song WL,Wang YJ,Ni YQ,Zhao Y,Li C,Wang Y,Li HH,Liang Z,Zhan JK,Liu YS
Wed Feb 01 00:00:00 EST 2023
Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI).
Molecular neurobiology
Zhan Z,Pan L,Zhu Y,Wang Y,Zhao Q,Liu Y,Li S,Wang H,Yang C,Yu L,Yin Y,Tan B
Wed Feb 01 00:00:00 EST 2023
BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.
Frontiers in cellular and infection microbiology
Li J,Lin H,Fan T,Huang L,Zhang X,Tai Y,Fang Y,Li Q,Zhao R,Wang P,Zhou L,Wan L,Wu Y,Zhong H,Wei C,Yang X
Mon Mar 27 00:00:00 EDT 2023
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Materials today. Bio
Wu F,Wang P,Wei X,Yang Y,Al Mamun A,Zhang X,Zhu Y,Mo T,Zhang H,Jiang C,Hu J,Xiao J
Wed Feb 01 00:00:00 EST 2023
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Cell cycle (Georgetown, Tex.)
Qi D,Chen P,Bao H,Zhang L,Sun K,Song S,Li T
Sat Apr 01 00:00:00 EDT 2023
Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice.
British journal of pharmacology
Li W,Xu H,Shao J,Chen J,Lin Y,Zheng Z,Wang Y,Luo W,Liang G
Thu Jun 01 00:00:00 EDT 2023
Low expression of SEMA4D as a potential predictive molecular marker of poor survival in patients with melanoma combined with liver cancer.
Oncology letters
Liu X,Zhang C,Yang WH,Li SC,Wang RF,Zhang YB,Zhang ZL
Sat Apr 01 00:00:00 EDT 2023
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Frontiers in immunology
Wen P,Wang R,Xing Y,Ouyang W,Yuan Y,Zhang S,Liu Y,Peng Z
Wed Mar 01 00:00:00 EST 2023
Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection.
Viruses
Niu Z,Zhang S,Xu S,Wang J,Wang S,Hu X,Zhang L,Ren L,Zhang J,Liu X,Zhou Y,Yang L,Song Z
Thu Apr 13 00:00:00 EDT 2023
Landscape of pathogenic mutations in premature ovarian insufficiency.
Nature medicine
Ke H,Tang S,Guo T,Hou D,Jiao X,Li S,Luo W,Xu B,Zhao S,Li G,Zhang X,Xu S,Wang L,Wu Y,Wang J,Zhang F,Qin Y,Jin L,Chen ZJ
Wed Feb 01 00:00:00 EST 2023
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
International journal of molecular sciences
Hou J,Wu H,Xu B,Shang J,Xu X,Li G,Zhang H,Zhang W,Deng Y,Hong X,Hu T,Zhang M,Zhan Y
Thu Feb 09 00:00:00 EST 2023
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
European journal of nuclear medicine and molecular imaging
Peng Z,Lu C,Shi G,Yin L,Liang X,Song G,Tian J,Du Y
Sat Apr 01 00:00:00 EDT 2023
Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.
Nature metabolism
Cheng H,Qiu Y,Xu Y,Chen L,Ma K,Tao M,Frankiw L,Yin H,Xie E,Pan X,Du J,Wang Z,Zhu W,Chen L,Zhang L,Li G
Wed Feb 01 00:00:00 EST 2023
Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.
Cell reports
Wu Z,Cao Z,Yao H,Yan X,Xu W,Zhang M,Jiao Z,Zhang Z,Chen J,Liu Y,Zhang M,Wang D
Tue Jul 25 00:00:00 EDT 2023
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
PLoS pathogens
Dai F,Guo M,Shao Y,Li C
Mon May 01 00:00:00 EDT 2023
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Toxicology and applied pharmacology
Song A,Ding T,Wei N,Yang J,Ma M,Zheng S,Jin H
Tue Aug 01 00:00:00 EDT 2023
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Toxins
Yang Y,Zheng S,Chu H,Du C,Chen M,Emran MY,Chen J,Yang F,Tian L
Sat Apr 01 00:00:00 EDT 2023
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Li Y,Liu B,Chen L,Lyu F,Zhang P,He Q,Cheng L,Liu C,Song Y,Xing Y
Sat Apr 01 00:00:00 EDT 2023
Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.
Functional & integrative genomics
Ma A,Sun Y,Ogbodu RO,Xiao L,Deng H,Zhou H
Tue Mar 28 00:00:00 EDT 2023
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
European journal of medicinal chemistry
Lin H,Han H,Yang M,Wen Z,Chen Q,Ma Y,Wang X,Wang C,Yin T,Wang X,Lu G,Chen H,Qi J,Yang Y
Sun Mar 05 00:00:00 EST 2023
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
The journal of gene medicine
Yao B,Cai Y,Wan L,Deng J,Zhao L,Wang W,Han Z
Thu Jun 01 00:00:00 EDT 2023
Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.
International journal of molecular sciences
Maurer J,Walles T,Wiese-Rischke C
Sat Feb 18 00:00:00 EST 2023
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea.
Chinese medicine
Li X,Yu X,Gao Y,Zhao W,Wang Y,Yu F,Fu C,Gao H,Cheng M,Li B
Wed May 24 00:00:00 EDT 2023
Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.
European journal of pharmacology
Cao H,Yang D,Nie K,Lin R,Peng L,Zhou X,Zhang M,Zeng Y,Liu L,Huang W
Sat Aug 05 00:00:00 EDT 2023
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma.
Journal of inflammation research
Li B,Liu J,Xu L,Xu Q,Liu Z,Liu T
Sun Apr 30 00:00:00 EDT 2023
Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.
International journal of molecular sciences
Rong Z,Li F,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Feb 03 00:00:00 EST 2023
Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.
International immunopharmacology
Wu Q,Chen X,Qiao C,Cao X,Du Q,Yuan Y,Zuo Y,Miao Y,Zheng Z,Zhang T,Zang L,Yang X,Shi W,Xie Z,Xu Y,Wu D,Wen C,Zheng H
Sun Jan 01 00:00:00 EST 2023
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Neuroscience
Hou JY,Zhou XL,Wang XY,Liang J,Xue Q
Tue Feb 21 00:00:00 EST 2023
Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
Cancer cell international
Nishikubo K,Ohgaki R,Liu X,Okanishi H,Xu M,Endou H,Kanai Y
Thu Jun 15 00:00:00 EDT 2023
Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway.
Toxicology
Li J,Wang W,Yuan Y,Cui X,Bian H,Wen H,Zhang X,Yu H,Wu H
Wed Mar 01 00:00:00 EST 2023
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Yun WJ,Xue H,Yang N,Xiao LJ,Sun HZ,Zheng HC
Sun Oct 01 00:00:00 EDT 2023
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas.
ACS nano
Pang HH,Huang CY,Chen PY,Li NS,Hsu YP,Wu JK,Fan HF,Wei KC,Yang HW
Tue Jun 13 00:00:00 EDT 2023
Heme oxygenase-1 protects against PM2.5 induced endothelial dysfunction through inhibition of HIF1α.
Environmental toxicology and pharmacology
Xu H,Wen Q,Xu X,Yu D,Liu Z,Zhang C,Zhang X,Ma J,Zhao H,Song L
Sun Jan 01 00:00:00 EST 2023
Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy.
Stem cells international
Zheng S,Zhang K,Zhang Y,He J,Ouyang Y,Lang R,Ao C,Jiang Y,Xiao H,Li Y,Li M,Li C,Wu D
Sat Apr 15 00:00:00 EDT 2023
Novel insights into the mediating roles of cluster of differentiation 36 in transmembrane transport and tissue partition of per- and polyfluoroalkyl substances in mice.
Journal of hazardous materials
Jia Y,Zhu Y,Wang R,Ye Q,Xu D,Zhang W,Zhang Y,Shan G,Zhu L
Sun Jan 15 00:00:00 EST 2023
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Microbiology spectrum
Lin L,Yang J,Zhang D,Lv Q,Wang F,Liu P,Wang M,Shi C,Huang X,Liang W,Tan C,Wang X,Chen H,Wilson BA,Wu B,Peng Z
Tue Mar 14 00:00:00 EDT 2023
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis.
Frontiers in immunology
Deng YX,Liu K,Qiu QX,Tang ZY,Que RM,Li DK,Gu XR,Zhou GL,Wu YF,Zhou LY,Yin WJ,Zuo XC
Tue Apr 18 00:00:00 EDT 2023
Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release.
Communications biology
Dong H,Han X,Hao M,Yang Q,Lyu Q,Tang D,Shen Z,Wang K,Kuang H,Cao G,Peng M,Shao M
Thu Feb 16 00:00:00 EST 2023
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Virologica Sinica
Zang L,Gu J,Yang X,Yuan Y,Guo H,Zhou W,Ma J,Chen Y,Wu Y,Zheng H,Shi W
Wed Feb 01 00:00:00 EST 2023
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Frontiers in immunology
Zhang H,Cao H,Luo H,Zhang N,Wang Z,Dai Z,Wu W,Liu G,Xie Z,Cheng Q,Cheng Y
Tue Feb 14 00:00:00 EST 2023
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
BMC cancer
Wang H,Cui H,Yang X,Peng L
Mon Mar 20 00:00:00 EDT 2023
Intermittent Fasting Alleviates Non-Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High-Fat and High-Cholesterol Diet Fed Mice.
Molecular nutrition & food research
Lin X,Zhu X,Xin Y,Zhang P,Xiao Y,He T,Guo H
Sat Jul 01 00:00:00 EDT 2023
DnaJC7 specifically regulates tau seeding.
bioRxiv : the preprint server for biology
Perez VA,Sanders DW,Mendoza-Oliva A,Stopschinski BE,Mullapudi V,White CL,Joachimiak LA,Diamond MI
Thu Mar 16 00:00:00 EDT 2023
An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
Science immunology
Ma S,Han J,Li Z,Xiao S,Zhang J,Yan J,Tang T,Barr T,Kraft AS,Caligiuri MA,Yu J
Fri Mar 17 00:00:00 EDT 2023
Tissue-resident CXCR4+ macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
International journal of cancer
Liao Z,Ye L,Li T,Jin X,Lin X,Fei Q,Zhang H,Shi S,Yu X,Jin K,Wu W
Thu Jun 01 00:00:00 EDT 2023
Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes.
Journal of ethnopharmacology
Lai Z,Li C,Ma H,Hua S,Liu Z,Huang S,Liu K,Li J,Feng Z,Cai Y,Zou Y,Tang Y,Jiang X
Tue May 23 00:00:00 EDT 2023
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
Disease models & mechanisms
Jiang XY,Guan FF,Ma JX,Dong W,Qi XL,Zhang X,Chen W,Gao S,Gao X,Pan S,Wang JZ,Ma YW,Zhang LF,Lu D
Mon May 01 00:00:00 EDT 2023
Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.
Blood
Yu Y,Woloshun RR,Lee JK,Ebea PO,Zhu S,Nemeth E,Garrick LM,Garrick MD,Collins JF
Thu Jul 13 00:00:00 EDT 2023
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
PLoS pathogens
Dong XD,Li Y,Li Y,Sun C,Liu SX,Duan H,Cui R,Zhong Q,Mou YG,Wen L,Yang B,Zeng MS,Luo MH,Zhang H
Mon May 01 00:00:00 EDT 2023
Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation.
Journal of nanobiotechnology
Zhang F,He X,Dong K,Yang L,Ma B,Liu Y,Liu Z,Chen B,Zhu R,Cheng L
Wed Mar 15 00:00:00 EDT 2023
ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD.
Molecular oncology
Qian Y,Zhang X,Mao S,Wei W,Lin X,Ling Q,Ye W,Li F,Pan J,Zhou Y,Zhao Y,Huang X,Huang J,Tong H,Sun J,Jin J
Sat Jul 01 00:00:00 EDT 2023
Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching.
Frontiers in cardiovascular medicine
Rong Z,Li F,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Feb 24 00:00:00 EST 2023
Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P2 hydrolysis in the plasma membrane.
The Journal of biological chemistry
Chen H,Lu C,Tan Y,Weber-Boyvat M,Zheng J,Xu M,Xiao J,Liu S,Tang Z,Lai C,Li M,Olkkonen VM,Yan D,Zhong W
Thu Jun 01 00:00:00 EDT 2023
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Environmental toxicology
Wang Y,Guo Y,Liu H,Du X,Shi L,Wang W,Zhang S
Thu Jun 01 00:00:00 EDT 2023
Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-[Formula: see text]B Signaling Pathway.
The American journal of Chinese medicine
Yang X,Han J,Huan Z,Xu C,Wang Q,Ge X
Mon Jun 19 00:00:00 EDT 2023
Dendrobium mixture ameliorates type 2 diabetes mellitus with non-alcoholic fatty liver disease through PPAR gamma: An integrated study of bioinformatics analysis and experimental verification.
Frontiers in pharmacology
Zhuang S,Zhang J,Lin X,Wang X,Yu W,Shi H
Tue Mar 07 00:00:00 EST 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Upregulation of PIK3IP1 monitors the anti-cancer activity of PI3Kα inhibitors in gastric cancer cells.
Biochemical pharmacology
Ma XB,Wang Y,Jia YJ,Liu YJ,Tian YQ,Liu Y,Hou GQ,Xu YC,Liu HM
Sun Jan 01 00:00:00 EST 2023
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Shock (Augusta, Ga.)
Deng M,He J,Hao C,Guo Y,Si H,Deng X,Zhang C,Li S,Yao S,Ren W,Yao W
Thu Jun 01 00:00:00 EDT 2023
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Environmental pollution (Barking, Essex : 1987)
Zheng Z,Halifu A,Ma J,Liu L,Fu Q,Yi B,Du E,Tian D,Xu Y,Zhang Z,Zhu J
Tue Aug 01 00:00:00 EDT 2023
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma.
Cell death discovery
Yang J,Li S,He J,Xu Q,Xie M,Yang C,Wang H,Zhang Y,Wan Q,Xiang M
Fri Apr 28 00:00:00 EDT 2023
Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Lin YK,Zhang F,Lei WJ,Gan XW,Li MD,Pan F,Wang WS,Sun K
Sat Apr 01 00:00:00 EDT 2023
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.
Cellular signalling
Hefni E,Menon D,Ma T,Asiedu EB,Sultan A,Meiller T,Schneider A,Sodhi A,Montaner S
Tue Aug 01 00:00:00 EDT 2023
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53flox/+LSL-KrasG12D/+Pdx-1-Cre murine models.
Cancer letters
Qiu J,Feng M,Yang G,Cao Z,Liu Y,You L,Zhang T
Wed Feb 01 00:00:00 EST 2023
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Life science alliance
Wang TX,Duan KL,Huang ZX,Xue ZA,Liang JY,Dang Y,Zhang A,Xiong Y,Ding C,Guan KL,Yuan HX
Sun Jan 01 00:00:00 EST 2023
Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b.
International journal of biological macromolecules
Song X,Chen Y,Chen X,Zhao X,Zou Y,Li L,Zhou X,Li M,Zhang D,Ye G,Jia R,Yin Z
Mon Jul 31 00:00:00 EDT 2023
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
Brain research
Gao S,Zhang L,Wang X,Li R,Han L,Xiong X,Jiang Q,Cheng D,Xiao X,Li H,Yang J
Tue Aug 01 00:00:00 EDT 2023
Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.
International journal of molecular sciences
Wacker M,Ball A,Beer HD,Schmitz I,Borucki K,Azizzadeh F,Scherner M,Awad G,Wippermann J,Veluswamy P
Thu Apr 13 00:00:00 EDT 2023
Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
JCI insight
Zhang X,Young C,Liao XH,Refetoff S,Torres M,Tomer Y,Stefan-Lifshitz M,Zhang H,Larkin D,Fang D,Qi L,Arvan P
Thu Jun 22 00:00:00 EDT 2023
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Redox biology
Wang Z,Tan C,Duan C,Wu J,Zhou D,Hou L,Qian W,Han C,Hou X
Sat Apr 01 00:00:00 EDT 2023
All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion.
International journal of molecular sciences
Kitakaze T,Tatsumi R,Yamaguchi M,Nakatsuji A,Harada N,Yamaji R
Sat May 20 00:00:00 EDT 2023
Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.
Journal of cancer research and clinical oncology
Liu HY,Wang FH,Liang JM,Xiang YY,Liu SH,Zhang SW,Zhu CM,He YL,Zhang CH
Sat Jul 01 00:00:00 EDT 2023
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Foods (Basel, Switzerland)
Zhao L,Miao Y,Shan B,Zhao C,Peng C,Gong J
Thu Mar 30 00:00:00 EDT 2023
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Neurochemical research
Li B,Lu Y,Wang R,Xu T,Lei X,Jin H,Gao X,Xie Y,Liu X,Zeng J
Wed Feb 01 00:00:00 EST 2023
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos.
Neural regeneration research
He BQ,Li AC,Hou YX,Li H,Zhang XY,Hao HF,Song HH,Cai RX,Wang YJ,Zhou Y,Wang YJ
Fri Sep 01 00:00:00 EDT 2023
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Neural regeneration research
Wen S,Zou ZR,Cheng S,Guo H,Hu HS,Zeng FZ,Mei XF
Thu Jun 01 00:00:00 EDT 2023
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
Cellular and molecular gastroenterology and hepatology
Xu C,Cheng S,Chen K,Song Q,Liu C,Fan C,Zhang R,Zhu Q,Wu Z,Wang Y,Fan J,Zheng H,Lu L,Chen T,Zhao H,Jiao Y,Qu C
Thu Jan 26 00:00:00 EST 2023
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
Molecular neurobiology
Gao YZ,Wu XM,Zhou ZQ,Liu PM,Yang JJ,Ji MH
Thu Jun 01 00:00:00 EDT 2023
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
Human cell
Yin L,Zhang Q,Xie S,Cheng Z,Li R,Zhu H,Yu Q,Yuan H,Wang C,Peng H,Zhang G
Sat Jul 01 00:00:00 EDT 2023
LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.
Biochemical and biophysical research communications
Xiao H,Yan A,Li M,Wang L,Xiang J
Sun Jan 22 00:00:00 EST 2023
Combinatorial expression of ebony and tan generates body color variation from nymph through adult stages in the cricket, Gryllus bimaculatus.
PloS one
Inoue S,Watanabe T,Hamaguchi T,Ishimaru Y,Miyawaki K,Nikawa T,Takahashi A,Noji S,Mito T
Mon May 22 00:00:00 EDT 2023
Pirfenidone suppressed triple-negative breast cancer metastasis by inhibiting the activity of the TGF-β/SMAD pathway.
Journal of cellular and molecular medicine
Luo D,Zeng X,Zhang S,Li D,Cheng Z,Wang Y,Long J,Hu Z,Long S,Zhou J,Zhang S,Zeng Z
Wed Feb 01 00:00:00 EST 2023
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Kidney international
Li J,Sun X,Yang N,Ni J,Xie H,Guo H,Wang X,Zhou L,Liu J,Chen S,Wang X,Zhang Y,Yu C,Zhang W,Lu L
Sun Jan 01 00:00:00 EST 2023
Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.
BMC complementary medicine and therapies
Qiu W,Wu Q,Zhang K,Da X,Tang K,Yuan N,Deng L,Wu M,Zhang Y,Quan J,Ma Q,Li X,Chen J
Wed Apr 12 00:00:00 EDT 2023
Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia.
Biochemical pharmacology
Ou ZY,Wang K,Shen WW,Deng G,Xu YY,Wang LF,Zai ZY,Ling YA,Zhang T,Peng XQ,Chen FH
Sat Apr 01 00:00:00 EDT 2023
Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.
Life sciences
Liu A,Li R,Zaaboul F,He M,Li X,Shi J,Liu Y,Xu YJ
Sat Jul 15 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.
Neurobiology of aging
Wang X,Hu M,Xie Q,Geng C,Jin C,Ren W,Fan J,Ma T,Hu B
Sun Jan 01 00:00:00 EST 2023
All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein.
Journal of virology
Frolov I,Agback T,Palchevska O,Dominguez F,Lomzov A,Agback P,Frolova EI
Thu Mar 30 00:00:00 EDT 2023
JMJD8 regulates neuropathic pain by affecting spinal cord astrocyte differentiation.
Neuroscience letters
Li Y,Zhang Y,Zhou Z,Yi L,Ji F,Zhang K,Zhang Y,Xu H
Thu Jul 13 00:00:00 EDT 2023
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Cell death and differentiation
Wang Y,Wang C
Sun Jan 01 00:00:00 EST 2023
Guanylate-binding protein 1 restricts avian coronavirus infectious bronchitis virus-infected HD11 cells.
Poultry science
Ma P,Gu K,Wen R,Li C,Zhou C,Zhao Y,Li H,Lei C,Yang X,Wang H
Wed Mar 01 00:00:00 EST 2023
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Life sciences
Lin JP,Huang MH,Sun ZT,Chen L,Lei YH,Huang YQ,Qi M,Fan SR,Chen SG,Chung CW,Chan MC,Liu JS,Hu M,Chen MF,Ye WC,Chen YY,Deng LJ
Sat Jul 01 00:00:00 EDT 2023
Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.
Human molecular genetics
Dang X,Zhang L,Franco A,Dorn Ii GW
Mon Mar 20 00:00:00 EDT 2023
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Cell death & disease
Yang C,Jin X,Liu X,Wu G,Yang W,Pang B,Jiang J,Liao D,Zhang Y
Fri Jan 20 00:00:00 EST 2023
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Nature communications
Ghate NB,Kim S,Shin Y,Kim J,Doche M,Valena S,Situ A,Kim S,Rhie SK,Lenz HJ,Ulmer TS,Mumenthaler SM,An W
Mon Apr 17 00:00:00 EDT 2023
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation.
Molecular and cellular neurosciences
Qin Y,Guo X,Song W,Liang Z,Wang Y,Feng D,Yang Y,Li M,Gao M
Wed Mar 01 00:00:00 EST 2023
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
The Journal of physiology
Chae SA,Du M,Son JS,Zhu MJ
Thu Jun 01 00:00:00 EDT 2023
NSUN2-mediated M5c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
Emerging microbes & infections
Wang H,Feng J,Zeng C,Liu J,Fu Z,Wang D,Wang Y,Zhang L,Li J,Jiang A,He M,Cao Y,Yan K,Tang H,Guo D,Xu K,Zhou X,Zhou L,Lan K,Zhou Y,Chen Y
Fri Dec 01 00:00:00 EST 2023
Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder.
Neural regeneration research
Li XH,Zhu HC,Cui XM,Wang W,Yang L,Wang LB,Hu NW,Duan DX
Tue Aug 01 00:00:00 EDT 2023
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
iScience
Zhang C,Liu Z,Wang X,Zhang B,Cui L,Hu Q,Hu B,Cao K,Shan W,Shi H,Wang R
Fri Jun 16 00:00:00 EDT 2023
Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltration.
Cancer cell international
Yan T,Yang H,Meng Y,Li H,Jiang Q,Liu J,Xu C,Xue Y,Xu J,Song Y,Chu X,Wang L,Chen X,Che F
Mon May 29 00:00:00 EDT 2023
A novel cuproptosis-related gene signature to predict prognosis in Glioma.
BMC cancer
Zhang M,Liu X,Wang D,Ruan X,Wang P,Liu L,Xue Y
Mon Mar 13 00:00:00 EDT 2023
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Bioengineering & translational medicine
Liang X,Zhang Y,Lin F,Li M,Li X,Chen Y,Liu J,Meng Q,Ma X,Wang E,Wei L,He Z,Fan H,Zhou X,Ding Y,Liu Z
Sun Jan 01 00:00:00 EST 2023
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Bioengineering & translational medicine
Liang X,Zhang Y,Lin F,Li M,Li X,Chen Y,Liu J,Meng Q,Ma X,Wang E,Wei L,He Z,Fan H,Zhou X,Ding Y,Liu Z
Sun Jan 01 00:00:00 EST 2023
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
The EMBO journal
Yi J,Wang L,Hu GS,Zhang YY,Du J,Ding JC,Ji X,Shen HF,Huang HH,Ye F,Liu W
Mon May 15 00:00:00 EDT 2023
MiR-133a/CD47 axis is a novel prognostic biomarker to promote triple negative breast cancer progression.
Pathology, research and practice
Yan H,Huang W,Chen C,Zhang X,Zhu K,Yuan J
Sat Apr 01 00:00:00 EDT 2023
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.
EMBO reports
Zhang Y,Cao X,Gao Z,Ma X,Wang Q,Xu X,Cai X,Zhang Y,Zhang Z,Wei G,Wen B
Thu Aug 03 00:00:00 EDT 2023
Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Journal of virology
Liu C,Zhao K,Chen Y,Yao Y,Tang J,Wang J,Xu C,Yang Q,Zheng Y,Yuan Y,Sun H,Zhang Y,Zhou Y,Chen J,Wang Y,Wu C,Pei R,Chen X
Wed May 31 00:00:00 EDT 2023
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy.
Cancer gene therapy
Liang X,Wang Z,Dai Z,Zhang H,Zhang J,Luo P,Liu Z,Liu Z,Yang K,Cheng Q,Zhang M
Wed Mar 01 00:00:00 EST 2023
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Environmental toxicology
Zhuge R,Li Z,He C,Ma W,Yan J,Xue Q,Wang R,Liu Y,Lu R,Du H,Yin F,Guo L
Wed Feb 01 00:00:00 EST 2023
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Advanced healthcare materials
Mo W,Liu S,Zhao X,Wei F,Li Y,Sheng X,Cao W,Ding M,Zhang W,Chen X,Meng L,Yao S,Diao W,Wei H,Guo H
Tue Aug 01 00:00:00 EDT 2023
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Sexual medicine
Tan XH,Gu YY,Song WP,Nan TG,Song WD,Fang D,Yuan YM,Xin ZC,Li XS,Guan RL
Wed Feb 01 00:00:00 EST 2023
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
International immunopharmacology
Shi X,Wu Y,Ni H,Li M,Qi B,Xu Y
Wed Feb 01 00:00:00 EST 2023
The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice.
Pharmaceutics
An Z,Zhang Y,Yu X,Xia J,Yin Y,Li G,Lu J,Fan X,Xu Y
Fri May 05 00:00:00 EDT 2023
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Stem cell research & therapy
Li H,Wei J,Zhang Z,Li J,Ma Y,Zhang P,Lin J
Thu Apr 13 00:00:00 EDT 2023
VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.
Neurochemical research
Zhang X,Sang X,Chen Y,Yu H,Sun Y,Liang X,Zheng X,Wang X,Yang H,Bi J,Zhang L,Wang P
Sun Oct 01 00:00:00 EDT 2023
Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder.
Journal of ethnopharmacology
Tian X,Ou G,Hu S,Wang C,Han F,Gao L
Thu Apr 06 00:00:00 EDT 2023
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
International journal of molecular sciences
Huang H,Yan J,Lan X,Guo Y,Sun M,Zhao Y,Zhang F,Sun J,Lu S
Tue Jan 03 00:00:00 EST 2023
Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway.
Frontiers in neuroscience
Wei W,Yao JX,Zhang TT,Wen JY,Zhang Z,Luo YM,Cao Y,Li H
Tue May 23 00:00:00 EDT 2023
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Food & function
Yu X,Zhang Y,Pei K,Tan J,Tian H,Xu T,Liu F,Peng N,Huang Y,Huang X,Huang X,Wu J,Liu Q,Zeng L,Hua W,Huang X
Thu May 11 00:00:00 EDT 2023
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
Cell
He K,Wan T,Wang D,Hu J,Zhou T,Tao W,Wei Z,Lu Q,Zhou R,Tian Z,Flavell RA,Zhu S
Thu Jul 06 00:00:00 EDT 2023
APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.
Cell death & disease
Zong C,Zhang Z,Gao L,He J,Wang Y,Li Q,Liu X,Yang J,Chen D,Huang R,Zheng G,Jin X,Wei W,Jia R,Shen J
Sat Jun 03 00:00:00 EDT 2023
Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.
Environmental science & technology
Zhang L,Shen L,Huang Y,Cui S,Zhao Q,Zhang C,Zhuang S,Jiang G
Tue Jul 11 00:00:00 EDT 2023
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Chiu CH,Wang LC
Tue Aug 01 00:00:00 EDT 2023
Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.
Redox biology
Li C,Chen X,Zhang S,Liang C,Ma X,Zhang R,Yan H
Thu Jun 01 00:00:00 EDT 2023
c-kit+VEGFR-2+ Mesenchymal Stem Cells Differentiate into Cardiovascular Cells and Repair Infarcted Myocardium after Transplantation.
Stem cell reviews and reports
Zhou P,Yu SN,Zhang HF,Wang YL,Tao P,Tan YZ,Wang HJ
Sun Jan 01 00:00:00 EST 2023
FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo.
Oncology letters
Zhao K,Gao J,Shi J,Shi C,Pang C,Li J,Guo W,Zhang S
Sun Jan 01 00:00:00 EST 2023
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.
The Journal of cell biology
Parker SS,Ly KT,Grant AD,Sweetland J,Wang AM,Parker JD,Roman MR,Saboda K,Roe DJ,Padi M,Wolgemuth CW,Langlais P,Mouneimne G
Mon May 01 00:00:00 EDT 2023
Proteome profiling of the prefrontal cortex of Fmr1 knockout mouse reveals enhancement of complement and coagulation cascades.
Journal of proteomics
Gao MM,Shi H,Yan HJ,Long YS
Wed Mar 15 00:00:00 EDT 2023
Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.
Arteriosclerosis, thrombosis, and vascular biology
Tian H,Yang X,Zhao J,Liu X,Liu X,Cai Y,Wehbe A,Ding Y,Yu S,Wei L,Liu L
Sat Jul 01 00:00:00 EDT 2023
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
NPJ breast cancer
Yang Z,Feng J,Jing J,Huang Y,Ye WW,Lei L,Wang XJ,Cao WM
Tue May 09 00:00:00 EDT 2023
CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activation.
Journal of geriatric cardiology : JGC
Zang GY,Yin Q,Shao C,Sun Z,Zhang LL,Xu Y,Li LH,Wang ZQ
Tue Mar 28 00:00:00 EDT 2023
Exosomal circCLIP1 regulates PM2.5-induced airway obstruction via targeting SEPT10 in vitro.
Ecotoxicology and environmental safety
Zhu H,Tang X,Zhang H,Zhou M,Liu H,Chu H,Zhang Z
Sat Apr 01 00:00:00 EDT 2023
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
The New phytologist
Park SH,Jeong JS,Huang CH,Park BS,Chua NH
Wed Feb 01 00:00:00 EST 2023
Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells.
The Journal of toxicological sciences
Kamimura M,Sasaki A,Otani Y,Nakamura Y,Nakamura T,Kuramochi K,Imai T,Kubo N,Okamoto S
Fri Jan 06 00:00:00 EST 2023
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Communications biology
Hu J,Jiang W,Zuo J,Shi D,Chen X,Yang X,Zhang W,Ma L,Liu Z,Xing Q
Tue Jan 17 00:00:00 EST 2023
CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response.
Cell transplantation
Cao L,Ma X,Zhang J,Yang M,He Z,Yang C,Li S,Rong P,Wang W
Wed Jan 18 00:00:00 EST 2023
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Frontiers in bioscience (Landmark edition)
Xiong D,Hu W,Han X,Cai Y
Thu May 25 00:00:00 EDT 2023
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
iScience
Ji X,Chu L,Su D,Sun J,Song P,Sun S,Wang Y,Mu Q,Liu Y,Wan Q
Fri May 19 00:00:00 EDT 2023
Protective Effect of Lonicera japonica on PM2.5-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway.
Antioxidants (Basel, Switzerland)
Lee HL,Kim JM,Go MJ,Kim TY,Joo SG,Kim JH,Lee HS,Kim HJ,Heo HJ
Thu Apr 20 00:00:00 EDT 2023
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Biochemical pharmacology
Fang T,Jiao Z,You Y,Cao J,Wang C,Liu J,Zhao W
Sat Apr 01 00:00:00 EDT 2023
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Neoplasma
Zhang H,Mao Y,Zou X,Niu J,Jiang J,Chen X,Zhu M,Yang X,Dong T
Wed Feb 01 00:00:00 EST 2023
Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo.
Oral diseases
Qiao S,Li B,Cai Q,Li Z,Yin Z,He J,Li Y,Meng W
Wed Nov 01 00:00:00 EDT 2023
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
Scientific reports
Huang PH,Duan XB,Tang ZZ,Zou ZX,Song WM,Gao G,Li D,Nie FQ,Yan X,Fu YX,Guo R,Xu YY
Fri Jan 13 00:00:00 EST 2023
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Pharmaceutical biology
Ding J,Lu B,Liu L,Zhong Z,Wang N,Li B,Sheng W,He Q
Fri Dec 01 00:00:00 EST 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury.
Respiratory research
Rao X,Zhou D,Deng H,Chen Y,Wang J,Zhou X,Jie X,Xu Y,Wu Z,Wang G,Dong X,Zhang S,Meng R,Wu C,Xing S,Fan K,Wu G,Zhou R
Tue Jan 24 00:00:00 EST 2023
Xuanhuang Runtong Tablets Relieve Slow Transit Constipation in Mice by Regulating TLR5/IL-17A Signaling Mediated by Gut Microbes.
Evidence-based complementary and alternative medicine : eCAM
Liang X,Wan D,Cai Y,Yue W,Wang X,Zhou H,Zhou R,Du Q,Xiao J,Zhang S
Thu Feb 02 00:00:00 EST 2023
Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.
PloS one
Kam JH,Shinhmar H,Powner MB,Hayes MJ,Aboelnour A,Jeffery G
Thu May 04 00:00:00 EDT 2023
LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p.
Cytokine
Hu C,Li S,Fu X,Zhao X,Peng J
Wed Feb 01 00:00:00 EST 2023
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Food & function
Zhou S,Liu J,Sun Y,Xu P,Liu JL,Sun S,Zhu B,Wu H
Mon Mar 20 00:00:00 EDT 2023
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
Veterinary microbiology
Xu D,Hu G,Luo J,Cheng J,Wu D,Cheng L,Huang X,Fu S,Liu J
Mon May 01 00:00:00 EDT 2023
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
European journal of pharmacology
Zhang ML,Wang M,Chen J,Liu YJ,Yu YJ,Liu LM,Zheng XH,Xiao YC,Zhang JM,Zhu MX,Yue X,Zhao Y,Niu W,Li ZC
Sun Mar 05 00:00:00 EST 2023
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway.
Journal of orthopaedic translation
Li C,Qin T,Jin Y,Hu J,Yuan F,Cao Y,Duan C
Wed Mar 01 00:00:00 EST 2023
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Scientific reports
Liu C,Lu J,Yuan T,Xie L,Zhang L
Fri Apr 14 00:00:00 EDT 2023
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Life science alliance
Si Z,Yang G,Wang X,Yu Z,Pang Q,Zhang S,Qian L,Ruan Y,Huang J,Yu L
Wed Mar 01 00:00:00 EST 2023
Themis suppresses the effector function of CD8+ T cells in acute viral infection.
Cellular & molecular immunology
Tang J,Jia X,Li J,Dong J,Wang J,Li W,Zhu Y,Hu Y,Hou B,Lin C,Cong Y,Ren T,Yan C,Yang H,Lai Q,Zheng H,Bao Y,Gautam N,Wang HR,Xu B,Chen XL,Li Q,Gascoigne NRJ,Fu G
Mon May 01 00:00:00 EDT 2023
Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.
Microbiology spectrum
Ning B,Shen J,Liu F,Zhang H,Jiang X
Thu Jun 15 00:00:00 EDT 2023
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Cell death & disease
Zou X,Ma L,Zhang Y,Zhang Q,Xu C,Zhang D,Chu Y,Zhang J,Li M,Zhang H,Wang J,Peng C,Wei G,Wu Y,Hou Z,Jia H
Wed Jun 28 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.
Cellular & molecular biology letters
Ju C,Ma Y,Zuo X,Wang X,Song Z,Zhang Z,Zhu Z,Li X,Liang Z,Ding T,Hu X,Wang Z
Thu Jan 19 00:00:00 EST 2023
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
Oncogene
Wang Y,Peng M,Zhong Y,Xiong W,Zhu L,Jin X
Wed Mar 01 00:00:00 EST 2023
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Acta biochimica et biophysica Sinica
Li W,Tao C,Mao M,Zhu K
Fri May 26 00:00:00 EDT 2023
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
World journal of gastrointestinal surgery
Zheng Z,Cao F,Ding YX,Lu JD,Fu YQ,Liu L,Guo YL,Liu S,Sun HC,Cui YQ,Li F
Thu Apr 27 00:00:00 EDT 2023
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
Journal of Cancer
Liu L,Li L,Zu W,Jing J,Liu G,Sun T,Xie Q
Mon Jun 19 00:00:00 EDT 2023
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zoological research
Zhang MF,Wan SC,Chen WB,Yang DH,Liu WQ,Li BL,Aierken A,Du XM,Li YX,Wu WP,Yang XC,Wei YD,Li N,Peng S,Li XL,Li GP,Hua JL
Thu May 18 00:00:00 EDT 2023
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Journal of agricultural and food chemistry
Liu D,Tian Q,Liu K,Ren F,Liu G,Zhou J,Yuan L,Fang Z,Zou B,Wang S
Wed Feb 08 00:00:00 EST 2023
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
International immunopharmacology
Li S,Liu H,Qian Y,Jiang L,Liu S,Liu Y,Liu C,Gu X
Sun Jan 01 00:00:00 EST 2023
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
American journal of cancer research
Han MT,Pei H,Sun QQ,Wang CL,Li P,Xie YY,Cao LJ,Zhang XX,Sun ZL
Sun May 14 00:00:00 EDT 2023
The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury.
Journal of chemical neuroanatomy
Cai Z,Zhang Z,Zhang L,Tan R,Wang Y,Sun M,Hu X,Ge Q,An J,Lu H
Fri Sep 01 00:00:00 EDT 2023
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
Hepatobiliary & pancreatic diseases international : HBPD INT
He RZ,Zheng JH,Yao HF,Xu DP,Yang MW,Liu DJ,Sun YW,Huo YM
Sat Apr 01 00:00:00 EDT 2023
HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation.
Cellular & molecular immunology
Wang Z,Yan C,Du Q,Huang Y,Li X,Zeng D,Mao R,Gurram RK,Cheng S,Gu W,Zhu L,Fan W,Ma L,Ling Z,Qiu J,Li D,Liu E,Zhang Y,Fang Y,Zhu J,Sun B
Sat Apr 01 00:00:00 EDT 2023
CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.
Proceedings of the National Academy of Sciences of the United States of America
Hu L,Zhao C,Liu M,Liu S,Ye J,Wang K,Shi J,Tian W,He X
Tue Mar 14 00:00:00 EDT 2023
TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.
Cancers
Wu Z,Lin C,Zhang F,Lu Z,Wang Y,Liu Y,Zhou Z,Li L,Song L
Thu Apr 13 00:00:00 EDT 2023
Disruption of the ADAM17/NF-κB feedback loop in astrocytes ameliorates HIV-1 Tat-induced inflammatory response and neuronal death.
Journal of neurovirology
Qiu X,Wang J,Zhang W,Duan C,Chen T,Zhang D,Su J,Gao L
Thu Jun 01 00:00:00 EDT 2023
CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang C,Wang ZQ,Zhang ZC,Lou G,Jin WL
Mon May 01 00:00:00 EDT 2023
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Environmental pollution (Barking, Essex : 1987)
Cui M,He Q,Wang Z,Yu Y,Gao H,Liu Z,Peng H,Wang H,Zhang X,Li D,Chen L,Xing X,Xiao Y,Chen W,Wang Q
Tue Aug 01 00:00:00 EDT 2023
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
International journal of biological sciences
Zhong C,Long Z,Yang T,Wang S,Zhong W,Hu F,Teoh JY,Lu J,Mao X
Tue Apr 18 00:00:00 EDT 2023
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
International immunopharmacology
Teng S,Zhu Z,Wu C,He Y,Zhou S
Thu Jun 01 00:00:00 EDT 2023
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Immunology
Gou Y,Wang H,Wang T,Wang H,Wang B,Jiao N,Yu Y,Cao Y,Wang H,Zhang Z
Wed Mar 01 00:00:00 EST 2023
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Frontiers in cardiovascular medicine
Tan Z,Chen P,Zheng Y,Pan Y,Wang B,Zhao Y
Fri Feb 24 00:00:00 EST 2023
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
The Journal of nutrition
Wang G,Qin S,Geng H,Zheng Y,Li R,Xia C,Chen L,Yao J,Deng L
Sat Jul 01 00:00:00 EDT 2023
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
Cell death and differentiation
Qin J,Huang T,Wang Z,Zhang X,Wang J,Dang Q,Cui D,Wang X,Zhai Y,Zhao L,Lu G,Shao C,Li S,Liu H,Liu Z
Sun Jan 01 00:00:00 EST 2023
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Cells
Kang SM,Seo S,Song EJ,Kweon O,Jo AH,Park S,Woo TG,Kim BH,Oh GT,Park BJ
Mon Apr 24 00:00:00 EDT 2023
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
Ecotoxicology and environmental safety
Huang J,Zou L,Bao M,Feng Q,Xia W,Zhu C
Sun Jan 01 00:00:00 EST 2023
1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Gan S,Fu L,Xu Y,Wang S,Zhang G,Pan D,Tao L,Shen X
Tue Aug 01 00:00:00 EDT 2023
N protein of PEDV plays chess game with host proteins by selective autophagy.
Autophagy
Zhai X,Kong N,Zhang Y,Song Y,Qin W,Yang X,Ye C,Ye M,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Zhang G,Tong G,Shan T
Tue Aug 01 00:00:00 EDT 2023
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.
Viruses
Wang H,Peng W,Wang J,Zhang C,Zhao W,Ran Y,Yang X,Chen J,Li H
Thu Apr 20 00:00:00 EDT 2023
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Journal of cellular and molecular medicine
Xie Y,Mei X,Shi W
Sat Apr 01 00:00:00 EDT 2023
Triptolide injection reduces Alzheimer's disease-like pathology in mice.
Synapse (New York, N.Y.)
Mao R,Xu S,Sun G,Yu Y,Zuo Z,Wang Y,Yang K,Zhang Z,Yang W
Mon May 01 00:00:00 EDT 2023
Sestrin2 contributes to BRAF inhibitor resistance via reducing redox vulnerability of melanoma cells.
Journal of dermatological science
Guo S,Yue Q,Wang S,Wang H,Ye Z,Zhang W,Shi Q,Gao T,Li C,Zhu G
Wed Feb 01 00:00:00 EST 2023
Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.
Immunopharmacology and immunotoxicology
Shao R,Lou X,Xue J,Yang Y,Ning D,Chen G,Jiang L
Thu Jun 01 00:00:00 EDT 2023
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Heliyon
Li Z,Xiang J,Mei S,Wu Y,Xu Y
Sat Apr 01 00:00:00 EDT 2023
PFC@O2 Targets HIF-1α to Reverse the Immunosuppressive TME in OSCC.
Journal of clinical medicine
Lan Z,Zou KL,Cui H,Chen H,Zhao YY,Yu GT
Tue Jan 10 00:00:00 EST 2023
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Clinical science (London, England : 1979)
Xing J,Qiao G,Luo X,Liu S,Chen S,Ye G,Zhang C,Yi J
Fri Mar 31 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Biological trace element research
Wang W,Zhang A
Mon May 01 00:00:00 EDT 2023
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.
Nature communications
Xiao F,Jiang H,Li Z,Jiang X,Chen S,Niu Y,Yin H,Shu Y,Peng B,Lu W,Li X,Li Z,Lan S,Xu X,Guo F
Tue May 02 00:00:00 EDT 2023
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Immunology
Ding L,Liang Y,Wang Y,Tong Z,Liu W,Tan S,Zhang J,Wang Y,Wu Z,Liang X,Ma C,Gao L
Sun Jan 01 00:00:00 EST 2023
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Cellular and molecular gastroenterology and hepatology
Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L
Thu Jan 26 00:00:00 EST 2023
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
The EMBO journal
Yao P,Zhang Z,Liu H,Jiang P,Li W,Du W
Mon Apr 17 00:00:00 EDT 2023
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
Journal of medical virology
Gao L,Gao Y,Han K,Wang Z,Meng F,Liu J,Zhao X,Shao Y,Shen J,Sun W,Liu Y,Xu H,Du X,Li J,Qin FX
Wed Mar 01 00:00:00 EST 2023
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Science advances
Jia M,Yue X,Sun W,Zhou Q,Chang C,Gong W,Feng J,Li X,Zhan R,Mo K,Zhang L,Qian Y,Sun Y,Wang A,Zou Y,Chen W,Li Y,Huang L,Yang Y,Zhao Y,Cheng X
Fri Jun 02 00:00:00 EDT 2023
Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.
Frontiers in microbiology
Li JH,Liu JL,Li XW,Liu Y,Yang JZ,Chen LJ,Zhang KK,Xie XL,Wang Q
Tue Apr 25 00:00:00 EDT 2023
Segregation of pathways leading to pexophagy.
Life science alliance
Barone FG,Urbé S,Clague MJ
Mon May 01 00:00:00 EDT 2023
Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.
Journal of assisted reproduction and genetics
Zhou M,Guo J,Li S,Li A,Fang Z,Zhao M,Zhang M,Wang X
Sat Jul 01 00:00:00 EDT 2023
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Behavioural brain research
Xiao Y,Guan T,Yang X,Xu J,Zhang J,Qi Q,Teng Z,Dong Y,Gao Y,Li M,Meng N,Lv P
Tue Mar 28 00:00:00 EDT 2023
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
Biochimica et biophysica acta. Molecular basis of disease
Bai Y,Shi JH,Liu Q,Yang DJ,Yan ZP,Zhang JK,Tang HW,Guo WZ,Jin Y,Zhang SJ
Thu Jun 01 00:00:00 EDT 2023
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
International journal of biological macromolecules
Xu Q,Zhang P,Han X,Ren H,Yu W,Hao W,Luo B,Khan MI,Chen N
Fri Jun 30 00:00:00 EDT 2023
E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer.
Annals of translational medicine
Gao H,Zhou F,Li R,Yuan J,Ye L
Tue Feb 28 00:00:00 EST 2023
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.
Cell reports
Wen L,Yang X,Wu Z,Fu S,Zhan Y,Chen Z,Bi D,Shen Y
Tue Apr 25 00:00:00 EDT 2023
Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer.
British journal of cancer
Ren J,Yu H,Li W,Jin X,Yan B
Sun Jan 01 00:00:00 EST 2023
Selective HDAC6 inhibitor TubA offers neuroprotection after intracerebral hemorrhage via inhibiting neuronal apoptosis.
PeerJ
Peng C,Gong X,Hu Z,Chen C,Jiang Z
Fri May 19 00:00:00 EDT 2023
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
International immunopharmacology
Shen PC,Huang SH,Liu ZM,Lu CC,Chou SH,Tien YC
Sat Jul 01 00:00:00 EDT 2023
A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis.
Acta biomaterialia
Guo ZX,Zhang Z,Yan JF,Xu HQ,Wang SY,Ye T,Han XX,Wang WR,Wang Y,Gao JL,Niu LN,Chang J,Jiao K
Wed Feb 01 00:00:00 EST 2023
Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.
Cellular signalling
Chen J,Liu W
Wed Mar 01 00:00:00 EST 2023
Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.
Animal biotechnology
Wu Y,Zhang W,Wang Y,Lu Q,Zhou J,Chen Z,Yang Z,Loor JJ
Fri Dec 01 00:00:00 EST 2023
Chromatin remodeler BRM is a key mediator of leucine-stimulated mTOR gene transcription in mouse mammary epithelial cells.
Biochemical and biophysical research communications
Ke C,Zhao S,Wang L,Zhang M,Gao X
Sun Feb 05 00:00:00 EST 2023
The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Cell death & disease
Li H,Jiang Y,Hu J,Xu J,Chen L,Zhang G,Zhao J,Zong S,Guo Z,Li X,Zhao X,Jing Z
Fri Jan 13 00:00:00 EST 2023
Molecular weight-dependent hyaluronic acid permeability and tight junction modulation in human buccal TR146 cell monolayers.
International journal of biological macromolecules
Park HY,Kweon DK,Kim JK
Wed Feb 01 00:00:00 EST 2023
NSUN2-mediated m5 C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
Clinical and translational medicine
Zuo S,Li L,Wen X,Gu X,Zhuang A,Li R,Ye F,Ge S,Fan X,Fan J,Chai P,Lu L
Mon May 01 00:00:00 EDT 2023
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Nature communications
Wang T,Zhou Y,Zhou Z,Zhang P,Yan R,Sun L,Ma W,Zhang T,Shen S,Liu H,Lu H,Ye L,Feng J,Chen Z,Zhong X,Wu G,Cai Y,Jia W,Gao P,Zhang H
Sat Mar 18 00:00:00 EDT 2023
Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome.
CNS neuroscience & therapeutics
He H,Zhang H,Chen H,He F,Yin F,Stauber T,Zou X,Peng J
Fri Dec 01 00:00:00 EST 2023
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin.
Journal of translational medicine
Zhang L,Liu J,Deng M,Chen X,Jiang L,Zhang J,Tao L,Yu W,Qiu Y
Thu Feb 02 00:00:00 EST 2023
A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis.
bioRxiv : the preprint server for biology
Luo G,Kumar H,Alridge K,Rieger S,Jiang E,Chan ER,Soliman A,Mahdi H,Letterio JJ
Thu Jun 29 00:00:00 EDT 2023
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Molecular nutrition & food research
Zhao F,Ma T,Zhang X,Zhao Q,Zhu K,Cao J,Liu Z,Shen X,Li C
Sat Apr 01 00:00:00 EDT 2023
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
Nature communications
Li L,Jiang D,Liu H,Guo C,Zhao R,Zhang Q,Xu C,Qin Z,Feng J,Liu Y,Wang H,Chen W,Zhang X,Li B,Bai L,Tian S,Tan S,Yu Z,Chen L,Huang J,Zhao JY,Hou Y,Ding C
Wed Mar 29 00:00:00 EDT 2023
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.
Antioxidants & redox signaling
Liu Y,Wang Y,Lin Z,Kang R,Tang D,Liu J
Sat Jul 01 00:00:00 EDT 2023
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
The Journal of cell biology
Gok MO,Connor OM,Wang X,Menezes CJ,Llamas CB,Mishra P,Friedman JR
Mon Apr 03 00:00:00 EDT 2023
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
Endocrinology
Hu S,Sun Z,Li B,Zhao H,Wang Y,Yao G,Li X,Bian X,Li TC,Vankelecom H,Sun Y
Mon Jan 09 00:00:00 EST 2023
Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration.
Molecular neurobiology
Zhang Y,Shen Y,Zhao L,Zhao Q,Zhao L,Yi S
Fri Sep 01 00:00:00 EDT 2023
The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharide.
Journal of animal science and biotechnology
Zheng W,Zhao Z,Yang Y,Ding L,Yao W
Sun Jun 11 00:00:00 EDT 2023
MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.
Cancer research and treatment
Yang Y,Qiu R,Weng Q,Xu Z,Song J,Zhao S,Meng M,Zhang D,Kong C,Wang H,Xu M,Zhao Z,Ji J
Sat Jul 01 00:00:00 EDT 2023
Phenylalanine diminishes M1 macrophage inflammation.
Science China. Life sciences
Zhang Q,Chen S,Guo Y,He F,Fu J,Ren W
Fri Dec 01 00:00:00 EST 2023
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.
Gut pathogens
Zhang J,Ning J,Fu W,Shi Y,Zhang J,Ding S
Mon Feb 13 00:00:00 EST 2023
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy.
Advanced materials (Deerfield Beach, Fla.)
Wu Y,Chang X,Yang G,Chen L,Wu Q,Gao J,Tian R,Mu W,Gooding JJ,Chen X,Sun S
Wed Mar 01 00:00:00 EST 2023
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Environment international
Ma N,Ma D,Liu X,Zhao L,Ma L,Ma D,Dong S
Mon May 01 00:00:00 EDT 2023
Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.
Molecular medicine (Cambridge, Mass.)
Ko HS,Laiman V,Tsao PN,Chen CM,Chuang HC
Mon Jan 30 00:00:00 EST 2023
Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis.
Biomaterials
Qi L,Han H,Han MM,Sun Y,Xing L,Jiang HL,Pandol SJ,Li L
Sun Jan 01 00:00:00 EST 2023
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.
European journal of histochemistry : EJH
Wang Z,Jian G,Chen T,Chen Y,Li J,Wang N
Wed Mar 01 00:00:00 EST 2023
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Orthopaedic surgery
Yao B,Cai Y,Wang W,Deng J,Zhao L,Han Z,Wan L
Wed Mar 01 00:00:00 EST 2023
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hu Y,Wen Q,Cai Y,Liu Y,Ma W,Li Q,Song F,Guo Y,Zhu L,Ge J,Zeng Q,Wang J,Yin C,Zheng G,Ge M
Sun Jan 01 00:00:00 EST 2023
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Molecular biotechnology
Jia Z,Yang M,Zhao Y,Li X,Yang C,Qiao L,Li H,Du J,Lin J,Guan L
Wed Feb 01 00:00:00 EST 2023
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Clinical and experimental medicine
Yang L,Zhao Q,Chen T,Liu W,Qiu X,Chen J,Huang S,Huang R,Dong L
Wed Nov 01 00:00:00 EDT 2023
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
Cell reports
Sun L,Zhang X,Wu S,Liu Y,Guerrero-Juarez CF,Liu W,Huang J,Yao Q,Yin M,Li J,Ramos R,Liao Y,Wu R,Xia T,Zhang X,Yang Y,Li F,Heng S,Zhang W,Yang M,Tzeng CM,Ji C,Plikus MV,Gallo RL,Zhang LJ
Tue Jun 27 00:00:00 EDT 2023
BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model.
Life sciences
Li G,Jiang X,Liang X,Hou Y,Zang J,Zhu B,Jia C,Niu K,Liu X,Xu X,Jiang R,Wang B
Sun Jan 15 00:00:00 EST 2023
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells.
Amino acids
Xu M,Zhou Y,Fan S,Zhang M,Gao X
Wed Feb 01 00:00:00 EST 2023
Combination of hyperlipidemia and 17β-Estradiol induces TMJOA-like pathological changes in rats.
Oral diseases
Zhao Y,Gan YH
Wed Nov 01 00:00:00 EDT 2023
LncRNA LINC00534 regulates cell proliferation and migration via the miR-494-3p/PTEN axis in HTR-8/SVneo cells.
Journal of clinical laboratory analysis
Song X,Zhang X,Xia Q,Li C,Zhang Y,Huang Y,Meng L,Wang C,Li J,Long W
Sun Jan 01 00:00:00 EST 2023
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Molecular neurobiology
Chen J,Zhu T,Yu D,Yan B,Zhang Y,Jin J,Yang Z,Zhang B,Hao X,Chen Z,Yan C,Yu J
Fri Sep 01 00:00:00 EDT 2023
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Genomics
Cai X,Zhu S
Mon May 01 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
rTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.
Brain and behavior
Liu Y,Liu X,Sun P,Li J,Nie M,Gong J,He A,Zhao M,Yang C,Wang Z
Sat Jul 01 00:00:00 EDT 2023
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Redox biology
Ji X,Hong J,Yang W,Yao M,Wang J,Jiang G,Wang Y,Li C,Lin J,Mou H,Li C,Li S,Chen Y,Shi M,Wang W,Lu F,Wu H,Zhao X,Qi Y,Yan S
Mon May 01 00:00:00 EDT 2023
Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution.
Gene therapy
Zhang R,Liu J,Xue G,Yang J,Li D,Tian T,Zhang X,Gao K,Pan Z
Wed Feb 01 00:00:00 EST 2023
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Marine life science & technology
Chen J,Xu L,Zhang XQ,Liu X,Zhang ZX,Zhu QM,Liu JY,Iqbal MO,Ding N,Shao CL,Wei MY,Gu YC
Mon May 01 00:00:00 EDT 2023
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.
Nature metabolism
Yang Z,Yan C,Ma J,Peng P,Ren X,Cai S,Shen X,Wu Y,Zhang S,Wang X,Qiu S,Zhou J,Fan J,Huang H,Gao Q
Sun Jan 01 00:00:00 EST 2023
High-frequency repetitive transcranial magnetic stimulation protects against cerebral ischemia/reperfusion injury in rats: Involving the mitigation of ferroptosis and inflammation.
Brain and behavior
Zhou GJ,Liu DN,Huang XR,Wu Q,Feng WB,Zeng YH,Liu HY,Yu J,Xiao ZJ,Zhou J
Mon May 01 00:00:00 EDT 2023
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
The Journal of pharmacy and pharmacology
Zhang X,Yang X,Zhang S,Wang J,Wang M,Ma T,Wan M,Lv X,Yan T,Jia Y
Fri Apr 07 00:00:00 EDT 2023
Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer.
Journal of traditional and complementary medicine
Huang W,Wen F,Ruan S,Gu P,Gu S,Song S,Zhou J,Li Y,Liu J,Shu P
Mon May 01 00:00:00 EDT 2023
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit.
Journal of molecular biology
Kozai D,Numoto N,Nishikawa K,Kamegawa A,Kawasaki S,Hiroaki Y,Irie K,Oshima A,Hanzawa H,Shimada K,Kitano Y,Fujiyoshi Y
Mon May 15 00:00:00 EDT 2023
mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Li X,Du ZJ,Xu JN,Liang ZM,Lin S,Chen H,Li SJ,Li XW,Yang JM,Gao TM
Sat Jul 01 00:00:00 EDT 2023
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.
Amino acids
Zhang Y,Han H,Qian Y,Wang Q,Jiang M
Sat Jul 01 00:00:00 EDT 2023
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
bioRxiv : the preprint server for biology
Zhang Q,Wan M,Mao Y
Tue Jan 24 00:00:00 EST 2023
Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.
Nature communications
Jia M,Wang Y,Wang J,Qin D,Wang M,Chai L,Fu Y,Zhao C,Gao C,Jia J,Zhao W
Tue Feb 07 00:00:00 EST 2023
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Cell chemical biology
Miao L,Yan C,Chen Y,Zhou W,Zhou X,Qiao Q,Xu Z
Thu Mar 16 00:00:00 EDT 2023
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.
Hepatology communications
Huang S,Wu B,He Y,Qiu R,Yang T,Wang S,Lei Y,Li H,Zheng F
Wed Mar 01 00:00:00 EST 2023
STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhu L,Wang Z,Sun X,Yu J,Li T,Zhao H,Ji Y,Peng B,Du M
Wed Feb 01 00:00:00 EST 2023
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Biomedicines
Lai KC,Regmi P,Liu CJ,Lo JF,Lee TC
Tue Mar 14 00:00:00 EDT 2023
African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.
Frontiers in microbiology
Chen Q,Li L,Guo S,Liu Z,Liu L,Tan C,Chen H,Wang X
Tue Apr 25 00:00:00 EDT 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Genes
Zhang H,Xie L,Zhang N,Qi X,Lu T,Xing J,Akhtar MF,Li L,Liu G
Sun Apr 30 00:00:00 EDT 2023
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
Frontiers in pharmacology
Zhao S,Sun Y,Wu X,Yang Y,Fan K,Hu K,Qin Y,Li K,Lin L,Chen K,Ma Y,Zhu M,Liu G,Zhang L
Fri Apr 28 00:00:00 EDT 2023
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
iScience
Ding L,Zhang Y,Wang Y,Wang Y,Tong Z,Li P,Chen C,Wang B,Yue X,Li C,Wu Z,Liang X,Ma C,Gao L
Fri Jun 16 00:00:00 EDT 2023
QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.
Evidence-based complementary and alternative medicine : eCAM
Yuan LS,Du H,Ren QY,Yang RL,Liu SW,Liu SY,Shi KF,Wang B,Meng XF,Li TX,Zhang N
Sat Feb 11 00:00:00 EST 2023
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wu J,Li J,Wu Y,Yang M,Chen Y,Wang N,Wang J,Yuan Z,Yi J,Yang C
Sat Jul 01 00:00:00 EDT 2023
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Oxidative medicine and cellular longevity
Chen Y,Zhang H,Li Y,Wang T
Mon Feb 06 00:00:00 EST 2023
Cofilin promotes tau pathology in Alzheimer's disease.
Cell reports
Yan M,Tang L,Dai L,Lei C,Xiong M,Zhang X,He M,Tian Y,Xiong J,Ke W,Zhang Z,Zhang C,Deng X,Zhang Z
Tue Feb 28 00:00:00 EST 2023
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.
Experimental animals
Xi J,Pan Y,Jin C,Liu J,Cheng J,Xu B
Wed May 17 00:00:00 EDT 2023
Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.
Rejuvenation research
Ma HH,Wen JR,Fang H,Su S,Wan C,Zhang C,Lu FM,Fan LL,Wu GL,Zhou ZY,Qiao LJ,Zhang SJ,Cai YF
Sat Apr 01 00:00:00 EDT 2023
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Behavioural brain research
Wang H,Pan MB,Jiang ST,Wang YC,Zhu Y,Zhang QC,Dong YF
Wed Feb 15 00:00:00 EST 2023
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
Journal of immunology (Baltimore, Md. : 1950)
Li L,Chen SN,Wang KL,Li N,Pang AN,Liu LH,Li B,Hou J,Wang S,Nie P
Mon May 15 00:00:00 EDT 2023
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.
Journal of translational medicine
Bai S,Zhao Y,Chen W,Peng W,Wang Y,Xiong S,Li Y,Yang Y,Chen S,Cheng B,Wang R
Fri Mar 31 00:00:00 EDT 2023
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Journal of neurochemistry
Li R,Zhang X,Gu L,Yuan Y,Luo X,Shen W,Xie Z
Mon May 01 00:00:00 EDT 2023
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Journal of ethnopharmacology
Wang SJ,Ye W,Li WY,Tian W,Zhang M,Sun Y,Feng YD,Liu CX,Liu SY,Cao W,Meng JR,Li XQ
Wed Mar 01 00:00:00 EST 2023
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Journal of hazardous materials
Mo Q,Kulyar MF,Quan C,Ding Y,Zhang Y,Zhang L,Pan H,Li J
Wed Feb 15 00:00:00 EST 2023
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Nutrients
Yan J,Ren C,Dong Y,Wali JA,Song H,Zhang Y,Zhang H,Kou G,Raubenheimer D,Cui Z
Tue Jan 03 00:00:00 EST 2023
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Molecular biology reports
Wei Y,Tan W,Qin H,Jin M,Yu H,Cheng J,Feng H
Sun Jan 01 00:00:00 EST 2023
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Journal of ethnopharmacology
Fu S,Song X,Tang X,Qian X,Du Z,Hu Y,Xu X,Zhang M
Mon Apr 24 00:00:00 EDT 2023
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
Food & function
Xu W,Song X,Qu Q,Gong Z,Xiao W
Tue Feb 21 00:00:00 EST 2023
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Autophagy
Liu Y,Zhang H,Liu Y,Zhang S,Su P,Wang L,Li Y,Liang Y,Wang X,Zhao W,Chen B,Luo D,Zhang N,Yang Q
Fri Sep 01 00:00:00 EDT 2023
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Cell & bioscience
Lai F,Wang H,Zhao X,Yang K,Cai L,Hu M,Lin L,Xia X,Li W,Cheng H,Zhou R
Thu Apr 06 00:00:00 EDT 2023
Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing.
Advanced materials (Deerfield Beach, Fla.)
Luo R,Liang Y,Yang J,Feng H,Chen Y,Jiang X,Zhang Z,Liu J,Bai Y,Xue J,Chao S,Xi Y,Liu X,Wang E,Luo D,Li Z,Zhang J
Sat Apr 01 00:00:00 EDT 2023
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Cancer research
Sun Y,Zhu L,Liu P,Zhang H,Guo F,Jin X
Thu Jun 15 00:00:00 EDT 2023
Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.
Nutrients
Zhang X,Zhang P,Liu Y,Liu Z,Xu Q,Zhang Y,Liu L,Yang X,Li L,Xue C
Mon Mar 06 00:00:00 EST 2023
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Aging and disease
Zhang Z,Li Y,Shi J,Zhu L,Dai Y,Fu P,Liu S,Hong M,Zhang J,Wang J,Jiang C
Thu Jun 01 00:00:00 EDT 2023
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Neurochemical research
Chen B,Wu J,Hu S,Liu Q,Yang H,You Y
Mon May 01 00:00:00 EDT 2023
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Translational research : the journal of laboratory and clinical medicine
Zhou J,Lu Y,Lin Y,Li C,Liu J,Jiang Z,Chen K
Tue Aug 01 00:00:00 EDT 2023
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Journal of cancer research and clinical oncology
Shen C,Yue X,Dai L,Wang J,Li J,Fang Q,Zhi Y,Shi C,Li W
Wed Feb 01 00:00:00 EST 2023
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Heliyon
Liu B,Su H
Wed Feb 01 00:00:00 EST 2023
Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.
Food & function
Cai D,Li X,Xu Q,Li H,Liu R,Chen J,Jiang X,Sun J,Lai C,Bai W
Tue Feb 21 00:00:00 EST 2023
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
Nature communications
Yan S,Zhou X,Wu C,Gao Y,Qian Y,Hou J,Xie R,Han B,Chen Z,Wei S,Gao X
Mon Mar 13 00:00:00 EDT 2023
Flavonoids dimers from the fruits of Psoralea corylifolia and their cytotoxicity against MCF-7 cells.
Bioorganic chemistry
Xu QX,Wang ZJ,He ZC,Xu J,Xu W,Yang XW
Sun Jan 01 00:00:00 EST 2023
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Toxicology and applied pharmacology
Qi Y,Hu M,Qiu Y,Zhang L,Yan Y,Feng Y,Feng C,Hou X,Wang Z,Zhang D,Zhao J
Sat Apr 15 00:00:00 EDT 2023
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
Aging
Peng S,Yu Y,Li J,Jiang D,Xu G,Wu L,Hu J
Fri Mar 17 00:00:00 EDT 2023
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.
Biochemical and biophysical research communications
Li R,Qin J,Wang Z,Lv F,Guo J,Zhu H,Huang Y
Sun Jan 01 00:00:00 EST 2023
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
iScience
Wang J,Li T,Zhou Y,Wang X,Carvalho V,Ni C,Li W,Wang Q,Chen Y,Shang Z,Qiu S,Sun Z
Fri Jun 16 00:00:00 EDT 2023
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
BMC molecular and cell biology
Chen J,Lei C,Zhang H,Huang X,Yang Y,Liu J,Jia Y,Shi H,Zhang Y,Zhang J,Du J
Fri Mar 03 00:00:00 EST 2023
STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment.
Mediators of inflammation
Li Y,Liu Y,Wang K,Xue D,Huang Y,Tan Z,Chen Y
Tue May 16 00:00:00 EDT 2023
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Frontiers in pharmacology
Ma P,Huang N,Tang J,Zhou Z,Xu J,Chen Y,Zhang M,Huang Q,Cheng Y
Sat Mar 04 00:00:00 EST 2023
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Journal of ethnopharmacology
Zhang Y,Wang S,Dai X,Liu T,Liu Y,Shi H,Yin J,Xu T,Zhang Y,Zhao D,Sukhorukov V,Orekhov AN,Gao S,Wang L,Zhang D
Thu Aug 10 00:00:00 EDT 2023
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Journal of orthopaedic translation
Chen D,Jiang X,Zou H
Wed Mar 01 00:00:00 EST 2023
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
The American journal of Chinese medicine
Hao Z,Zhang Z,Zhao Y,Wang D
Fri Mar 31 00:00:00 EDT 2023
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Wang S,Zhou L,Ji N,Sun C,Sun L,Sun J,Du Y,Zhang N,Li Y,Liu W,Lu W
Sat Jul 01 00:00:00 EDT 2023
Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.
Journal of the American Society of Nephrology : JASN
Peng J,Wang Y,Han X,Zhang C,Chen X,Jin Y,Yang Z,An Y,Zhang J,Liu Z,Chen Y,Gao E,Zhang Y,Xu F,Zheng C,Zhou Q,Liu Z
Wed Feb 01 00:00:00 EST 2023
Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum.
Journal of natural products
Qi Y,Wang Z,Zhang J,Tang S,Zhu H,Jiang B,Li X,Wang J,Sun Z,Zhao M,Zhu H,Yan P
Fri May 26 00:00:00 EDT 2023
Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus.
International immunopharmacology
Wang J,Yang J,Xia W,Zhang M,Tang H,Wang K,Zhou C,Qian L,Fan Y
Thu Jun 01 00:00:00 EDT 2023
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Cancer gene therapy
Fu J,Liu G,Zhang X,Lei X,Liu Q,Qian K,Tong Q,Qin W,Li Z,Cao Z,Zhang J,Liu C,Wang Z,Liu Z,Liang XM,Yamamoto H,Xu X
Mon May 01 00:00:00 EDT 2023
Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Ben H,Luo C,Cheng J,Zeng CH,Zhou Y,Jeon IH,Sun Y
Sat Jul 01 00:00:00 EDT 2023
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
International journal of biological macromolecules
Chen HX,Wang XC,Hou HT,Wang J,Yang Q,Chen YL,Chen HZ,He GW
Sat Jul 01 00:00:00 EDT 2023
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
International journal of molecular sciences
Li L,Lv L,Xu JC,He Q,Chang N,Cui YY,Tao ZC,Zhu T,Qian LT
Wed Mar 15 00:00:00 EDT 2023
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Neural regeneration research
Cui YR,Bu ZQ,Yu HY,Yan LL,Feng J
Sat Jul 01 00:00:00 EDT 2023
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Biochemical and biophysical research communications
Wu F,Tu C,Zhang K,Che H,Lin Q,Li Z,Zhou Q,Tang B,Yang Y,Chen M,Shao C
Sun Jan 15 00:00:00 EST 2023
RBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition.
Cancer research
Bao Y,Zhang S,Zhang X,Pan Y,Yan Y,Wang N,Ren Y,Zuo J,Zong WX,Wang Z,Wang Y
Tue May 02 00:00:00 EDT 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
Sat Apr 01 00:00:00 EDT 2023
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
Cell biology international
Lu B,Nie XH,Yin R,Ding P,Su ZZ,Qiu S,Qian YF
Sat Apr 01 00:00:00 EDT 2023
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Cellular oncology (Dordrecht)
Huang S,Zhang NQ,Xu CJ,Huang WQ,Li DX,Li J,Yao LL,Sundquist K,Sundquist J,Jiang SH,Xing X,Hu LP,Zhang ZG,Ji J,Zhang XL
Tue Aug 01 00:00:00 EDT 2023
Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration.
Evidence-based complementary and alternative medicine : eCAM
Yang Y,Wang Y,Liu X,Deng Y,Lu J,Jiang F,Nie F,Peng J,Peng Q,Qin Y
Tue Feb 14 00:00:00 EST 2023
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Integrative medicine research
Weng H,Wang Q,Ye R,Bai Y,Yang H,Xu G,Wang Q
Thu Jun 01 00:00:00 EDT 2023
A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.
Phenomics (Cham, Switzerland)
Lu Q,Du Y,Zhang Y,Chen Y,Li H,He W,Tang Y,Zhao Z,Zhang Y,Wu J,Zhu X,Lu Y
Thu Jun 01 00:00:00 EDT 2023
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Cancer gene therapy
Gong W,Guo Y,Yuan H,Chai R,Wan Z,Zheng B,Hu X,Chen B,Gao S,Dai Q,Yu P,Tu S
Thu Jun 01 00:00:00 EDT 2023
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Cell biology and toxicology
Liu L,Wang J,Zhang J,Huang C,Yang Z,Cao Y
Wed Feb 01 00:00:00 EST 2023
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Colloids and surfaces. B, Biointerfaces
Chen C,Chen Y,Lan YJ,Tian MN,Zhang YM,Lei ZY,Fan DL
Wed Feb 01 00:00:00 EST 2023
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Theranostics
Tao G,Liu F,Jin Z,Liu B,Wang H,Li D,Tang W,Chen Y,He Q,Qin S
Wed May 24 00:00:00 EDT 2023
Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.
International journal of hematology
Imai Y,Nagaya S,Araiso Y,Meguro-Horike M,Togashi T,Ohmori K,Makita Y,Sato E,Yujiri T,Nagamori Y,Horike SI,Watanabe A,Morishita E
Sat Apr 01 00:00:00 EDT 2023
Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
Wu X,Wu Q,Wang Y,Liu Y,Li Z,Liu Q,Huang Z,Li M,Zhang B,Zhan Q
Sun Apr 30 00:00:00 EDT 2023
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Molecular therapy : the journal of the American Society of Gene Therapy
Liu JL,Zhang L,Huang Y,Li XH,Liu YF,Zhang SM,Zhao YE,Chen XJ,Liu Y,He LY,Dong Z,Liu FY,Sun L,Xiao L
Wed May 03 00:00:00 EDT 2023
Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy.
Research square
Zack SR,Nikolaienko R,Cook B,Melki R,Zima AV,Campbell EM
Fri Jan 27 00:00:00 EST 2023
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
The Journal of investigative dermatology
Kang T,Zhang C,Lei H,Luo R,Liu M,Wang S,Zhang X,Duan Q,Xiao S,Zheng Y
Thu Jun 01 00:00:00 EDT 2023
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Journal of neuroinflammation
Huang C,Sun L,Xiao C,You W,Sun L,Wang S,Zhang Z,Liu S
Fri Feb 17 00:00:00 EST 2023
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
The FEBS journal
Zhang X,Li S,Ren X,Xiang P,Zhang Y,Wang T,Qin Q,Sun F,Liu J,Gao L,Ma C,Yue X,Yang X,Han S,Liang X
Wed Feb 01 00:00:00 EST 2023
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
Nutrients
Kuo HN,LaRussa Z,Xu FM,West K,Consitt L,Davidson WS,Liu M,Coschigano KT,Shi H,Lo CC
Fri May 26 00:00:00 EDT 2023
Caffeine can alleviate non-alcoholic fatty liver disease by augmenting LDLR expression via targeting EGFR.
Food & function
Huang YW,Wang LT,Zhang M,Nie Y,Yang JB,Meng WL,Wang XJ,Sheng J
Mon Apr 03 00:00:00 EDT 2023
MAVS-Based Reporter Systems for Real-Time Imaging of EV71 Infection and Antiviral Testing.
Viruses
Li X,Yang E,Li X,Fan T,Guo S,Yang H,Wu B,Wang H
Wed Apr 26 00:00:00 EDT 2023
Identification of hub genes and pathways in lung metastatic colorectal cancer.
BMC cancer
Dai W,Guo C,Wang Y,Li Y,Xie R,Wu J,Yao B,Xie D,He L,Li Y,Huang H,Wang Y,Liu S
Thu Apr 06 00:00:00 EDT 2023
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Antiviral research
Zheng J,Deng Y,Wei Z,Zou H,Wen X,Cai J,Zhang S,Jia B,Lu M,Lu K,Lin Y
Mon May 01 00:00:00 EDT 2023
Rs15285, a functional polymorphism located in lipoprotein lipase, predicts the risk and prognosis of gastric cancer.
Applied microbiology and biotechnology
Shen K,Zhou X,Hu L,Xiao J,Cheng Q,Wang Y,Liu K,Fan H,Xu Z,Yang L
Mon May 01 00:00:00 EDT 2023
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Heliyon
Gao L,Tong S,Liu J,Cai J,Ye Z,Zhou L,Song P,Li Z,Lei P,Wei H,Hua Q,Tian D,Cai Q
Thu Jun 01 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
miR-100-5p Regulates Skeletal Muscle Myogenesis through the Trib2/mTOR/S6K Signaling Pathway.
International journal of molecular sciences
Wang K,Liufu S,Yu Z,Xu X,Ai N,Li X,Liu X,Chen B,Zhang Y,Ma H,Yin Y
Wed May 17 00:00:00 EDT 2023
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Laboratory investigation; a journal of technical methods and pathology
Cai MN,Chen DM,Xiao LX,Li SS,Liao CH,Li J,Huang ZX,Wang JL,Gu YR,Gu L,Huang YH,Lian YF
Sat Jul 01 00:00:00 EDT 2023
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
EMBO molecular medicine
Southwell N,Primiano G,Nadkarni V,Attarwala N,Beattie E,Miller D,Alam S,Liparulo I,Shurubor YI,Valentino ML,Carelli V,Servidei S,Gross SS,Manfredi G,Chen Q,D'Aurelio M
Mon Jul 10 00:00:00 EDT 2023
PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy.
Biomaterials
Wang L,Fu B,Hou DY,Lv YL,Yang G,Li C,Shen JC,Kong B,Zheng LB,Qiu Y,Wang HL,Liu C,Zhang JJ,Bai SY,Li LL,Wang H,Xu WH
Mon May 01 00:00:00 EDT 2023
Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development.
Cellular & molecular biology letters
Wang H,Liang W,Wang X,Zhan Y,Wang W,Yang L,Zhu Y
Mon Jun 26 00:00:00 EDT 2023
A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.
Molecular neurobiology
Guo D,Huang F,Xue R,Ma Y,Xiao L,Lou H,Pan S
Wed Mar 01 00:00:00 EST 2023
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
International immunopharmacology
Zhang H,Zhang X,Ling C,Liu C,Hua S,Xiong Z,Zhao H,Feng Q,Feng Z,Tang J,Hong X
Sat Apr 01 00:00:00 EDT 2023
Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.
Journal of cellular and molecular medicine
Wang J,Zhang J,Ma Q,Zhang S,Ma F,Su W,Zhang T,Xie X,Di C
Sat Apr 01 00:00:00 EDT 2023
Interleukin-1 increases cyclooxygenase-2 expression and prostaglandin E2 production in human granulosa-lutein cell via nuclear factor kappa B/P65 and extracellular signal-regulated kinase 1/2 signaling pathways.
Molecular and cellular endocrinology
Wan S,Chen Q,Xiang Y,Sang Y,Tang M,Song Y,Feng G,Ye B,Bai L,Zhu Y
Mon May 01 00:00:00 EDT 2023
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
ACS chemical neuroscience
Zhang Z,Guo L,Yang F,Peng S,Wang D,Lai X,Su B,Xie H
Wed May 17 00:00:00 EDT 2023
Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.
International immunopharmacology
Chen J,Luo W,Hu C,Ren M,Xu H,Xu X,Li W,Chen Y,Shao J,Xiao Z,Lv X,Liang G
Mon May 01 00:00:00 EDT 2023
Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release.
Molecular metabolism
Greenwood MP,Greenwood M,Bárez-López S,Hawkins JW,Short K,Tatovic D,Murphy D
Sat Apr 01 00:00:00 EDT 2023
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang L,Wo C,Yuan Y,Cao H,Tan W,Zhou X,Wang D,Chen R,Shi M,Zhang F,Xiao Y,Liu L,Zhou Y,Zhang T,Wang Y,Guo B
Wed Mar 01 00:00:00 EST 2023
Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro.
International journal of molecular sciences
Wang C,Liu C,Liang C,Qu X,Zou X,Du S,Zhang Q,Wang L
Tue Mar 28 00:00:00 EDT 2023
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.
Cell death and differentiation
Zhu Y,Zhang H,Mao H,Zhong S,Huang Y,Chen S,Yan K,Zhao Z,Hao X,Zhang Y,Yao H,Huang X,Wang M,Zhang W,Li J,Meng G,Qin X,Ye Z,Shen J,Song Y,Xu Y,Yang Z,Wang L,Zhang Y,Wen L
Sun Jan 01 00:00:00 EST 2023
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Cellular oncology (Dordrecht)
Wang S,Liu X,Zhou T,Li J,Lin Y,Zhou A,Huang J,Zhao J,Cai J,Cai X,Huang Y,Li X
Wed Feb 01 00:00:00 EST 2023
Paeoniflorin-6'-O-benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β-arrestin 2 on ERK1/2-NF-κB.
Phytotherapy research : PTR
Jiang M,Tang C,Yang M,Li Y,Wang W,Wang C,Wei W,Chen J
Wed Feb 01 00:00:00 EST 2023
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
International journal of molecular sciences
Gao Z,Shao D,Zhao C,Liu H,Zhao X,Wei Q,Ma B
Tue May 16 00:00:00 EDT 2023
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Metallomics : integrated biometal science
Abdurahman A,Li Y,Jia SZ,Xu XW,Lin SJ,Ouyang P,Jun He Z,Zhang ZH,Liu Q,Xu Y,Song GL
Mon Apr 03 00:00:00 EDT 2023
Identification of miR-30c-5p as a tumor suppressor by targeting the m6 A reader HNRNPA2B1 in ovarian cancer.
Cancer medicine
Wu Q,Li G,Gong L,Cai J,Chen L,Xu X,Liu X,Zhao J,Zeng Y,Gao R,Yu L,Wang Z
Wed Feb 01 00:00:00 EST 2023
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
Molecular neurobiology
Chen HL,Yang L,Zhang XL,Jia QY,Duan ZD,Li JJ,Zheng LY,Liu TT,Qi Z,Yuan Y,Wu CY
Tue Aug 01 00:00:00 EDT 2023
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
Journal of ethnopharmacology
Zhang PP,Zhuo BY,Duan ZW,Li X,Huang SL,Cao Q,Zhao T,Wei SL,Hu XH,Zhang Y
Thu Aug 10 00:00:00 EDT 2023
Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice.
BMC genomics
Liang Y,Song C,Li J,Li T,Zhang C,Zou Y
Thu Feb 09 00:00:00 EST 2023
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
Cell biology international
Qin D,Lei Y,Xie W,Zheng Q,Peng Z,Liu Y,Dai B,Ma T,Wei P,Gao C,Guo X,Gao J,Zhao J,Du J,Zeng Q,Zhang Z,Dong X,Shen H
Wed Mar 01 00:00:00 EST 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Cell reports
Fei X,Huang J,Li F,Wang Y,Shao Z,Dong L,Wu Y,Li B,Zhang X,Lv B,Zhao Y,Weng Q,Chen K,Zhang M,Yang S,Zhang C,Zhang M,Li W,Ying S,Sun Q,Chen Z,Shen H
Tue Jun 27 00:00:00 EDT 2023
The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.
Acta biochimica et biophysica Sinica
Lu Y,Huang P,Li Y,Liu W,Li J,Zhao R,Feng H,Shi C,Cao G
Wed May 24 00:00:00 EDT 2023
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Journal of the American Chemical Society
Jin Y,Fan J,Wang R,Wang X,Li N,You Q,Jiang Z
Wed Apr 05 00:00:00 EDT 2023
CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.
Genes to cells : devoted to molecular & cellular mechanisms
Yamasaki A,Maruyama-Takahashi K,Nishida K,Okazaki S,Okita K,Akiyama Y,Suzuki H,Endo Y,Masuko K,Masuko T,Tomioka Y
Mon May 01 00:00:00 EDT 2023
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.
International journal of molecular sciences
He Z,Chang T,Chen Y,Wang H,Dai L,Zeng H
Tue Mar 28 00:00:00 EDT 2023
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
Pharmacological research
Gu L,Jin X,Liang H,Yang C,Zhang Y
Thu Jun 01 00:00:00 EDT 2023
Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.
Stem cell reviews and reports
Sun J,Xu G
Tue Aug 01 00:00:00 EDT 2023
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Neural plasticity
Meng P,Zhang X,Li D,Yang H,Lin X,Zhao H,Li P,Wang Y,Wang X,Ge J
Wed Jan 18 00:00:00 EST 2023
Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Chang CM,Cheng KH,Wei TY,Lu MP,Chen YC,Lu YT
Mon May 01 00:00:00 EDT 2023
MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.
Pediatric pulmonology
Wang J,Zhang A,Huang F,Xu J,Zhao M
Mon May 01 00:00:00 EDT 2023
Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.
Biochemical and biophysical research communications
Zeng R,Zeng Y,Wang Q,Li X,Liu J,Li B,Zhang G,Hu S
Sun Apr 23 00:00:00 EDT 2023
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Journal of ethnopharmacology
Qi J,Luo Q,Zhang Q,Wu M,Zhang L,Qin L,Xue Q,Nie X
Mon Jun 12 00:00:00 EDT 2023
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
BioFactors (Oxford, England)
Xu W,Ding J,Li B,Sun T,You X,He Q,Sheng W
Wed Mar 01 00:00:00 EST 2023
Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway.
Cellular signalling
Zhan XJ,Wang R,Kuang XR,Zhou JY,Hu XL
Thu Jun 01 00:00:00 EDT 2023
Identification of immune signatures in Parkinson's disease based on co-expression networks.
Frontiers in genetics
Dong X,Li Y,Li Q,Li W,Wu G
Sat Feb 04 00:00:00 EST 2023
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Neuron
Festa BP,Siddiqi FH,Jimenez-Sanchez M,Won H,Rob M,Djajadikerta A,Stamatakou E,Rubinsztein DC
Wed Jul 05 00:00:00 EDT 2023
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours.
Journal of mammary gland biology and neoplasia
Seitz J,Bilsland A,Puget C,Baasner I,Klopfleisch R,Stein T
Tue Jul 04 00:00:00 EDT 2023
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
British journal of pharmacology
Dong T,Fan X,Zheng N,Yan K,Hou T,Peng L,Ci X
Sun Oct 01 00:00:00 EDT 2023
Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.
International immunopharmacology
Lu H,Gong H,Du J,Gao W,Xu J,Cai X,Yang Y,Xiao H
Thu Jun 01 00:00:00 EDT 2023
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
European journal of immunology
Duan Z,Ma L,Jin J,Ma L,Ye L,Wu J,Luo Y
Tue Aug 01 00:00:00 EDT 2023
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
Journal of applied toxicology : JAT
Zhao J,Song G,Weng F,Li Y,Zou B,Jin J,Yan D,Sun X,Liu C,Qiu FR
Sat Jul 01 00:00:00 EDT 2023
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression.
Journal of ethnopharmacology
Liu EY,Yang CL,Tsai JC,Cheng HY,Peng WH
Mon Jun 12 00:00:00 EDT 2023
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2.
Journal of medicinal chemistry
Zhang Y,Yang H,Li B,Li J,Li H,Shi Q,Li B,Wang Z,Zheng J,Zhang Y,Dong H,Huang X,Wang Y
Thu Jun 08 00:00:00 EDT 2023
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
European journal of pharmacology
Otkur W,Wang J,Hou T,Liu F,Yang R,Li Y,Xiang K,Pei S,Qi H,Lin H,Zhou H,Zhang X,Piao HL,Liang X
Thu Jun 15 00:00:00 EDT 2023
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.
Journal of ethnopharmacology
Zhu Y,Han Q,Wang L,Wang B,Chen J,Cai B,Wu C,Zhu X,Liu F,Han D,Dong H,Jia Y,Liu Y
Mon Jan 30 00:00:00 EST 2023
Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.
Clinical and experimental hypertension (New York, N.Y. : 1993)
Li W,Li SG,Li L,Yang LJ,Li ZS,Li X,Ye AY,Xiong Y,Zhang Y,Xiong YY
Sun Dec 31 00:00:00 EST 2023
MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.
Toxicology
Liu M,Yu Z,Zhao Z,Yang F,Zhou M,Wang C,Tian X,Zhang B,Liang G,Liu X,Shao J
Thu Jun 01 00:00:00 EDT 2023
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
The clinical respiratory journal
Yang JJ,Yang YJ,Gu YL,Tong L,Liu YF,Zhang JG
Tue Aug 01 00:00:00 EDT 2023
The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.
Reproductive biology
Huang X,Liu X,Zhang X,Yang Y,Gao H,Gao J,Bao H,Zhao L,Yang G,Zhang Y,Liu D
Fri Sep 01 00:00:00 EDT 2023
Characterization of dominant-negative growth hormone receptor variants reveals a potential therapeutic target for short stature.
European journal of endocrinology
Andrews A,Cottrell E,Maharaj A,Ladha T,Williams J,Schilbach K,Kaisinger LR,Perry JRB,Metherell LA,McCormick PJ,Storr HL
Tue Apr 04 00:00:00 EDT 2023
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Science immunology
Hao Q,Zhan C,Lian C,Luo S,Cao W,Wang B,Xie X,Ye X,Gui T,Voena C,Pighi C,Wang Y,Tian Y,Wang X,Dai P,Cai Y,Liu X,Ouyang S,Sun S,Hu Q,Liu J,Ye Y,Zhao J,Lu A,Wang JY,Huang C,Su B,Meng FL,Chiarle R,Pan-Hammarström Q,Yeap LS
Fri Mar 31 00:00:00 EDT 2023
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Nutrients
Xie Z,Zhang G,Liu R,Wang Y,Tsapieva AN,Zhang L,Han J
Tue Apr 04 00:00:00 EDT 2023
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Journal of experimental & clinical cancer research : CR
Liu Y,Xu Q,Deng F,Zheng Z,Luo J,Wang P,Zhou J,Lu X,Zhang L,Chen Z,Zhang Q,Chen Q,Zuo D
Wed Feb 01 00:00:00 EST 2023
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Journal of orthopaedic translation
Chen Y,Liu Y,Jiang K,Wen Z,Cao X,Wu S
Wed Mar 01 00:00:00 EST 2023
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Zhou F,Gao H,Shang L,Li J,Zhang M,Wang S,Li R,Ye L,Yang S
Mon Jun 19 00:00:00 EDT 2023
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Frontiers in immunology
Luo M,Chen Y,Pan X,Chen H,Fan L,Wen Y
Tue Jun 13 00:00:00 EDT 2023
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
Cell death & disease
Zhang S,Tong X,Liu S,Huang J,Zhang L,Zhang T,Wang D,Fan H
Fri Jun 30 00:00:00 EDT 2023
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function.
Acta pharmacologica Sinica
Sun JX,Zhu KY,Wang YM,Wang DJ,Zhang MZ,Sarlus H,Benito-Cuesta I,Zhao XQ,Zou ZF,Zhong QY,Feng Y,Wu S,Wang YQ,Harris RA,Wang J
Sat Apr 01 00:00:00 EDT 2023
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Advanced healthcare materials
Sun T,Li J,Zeng C,Luo C,Luo X,Li H
Sun Jan 01 00:00:00 EST 2023
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
American journal of physiology. Cell physiology
Zhao J,Yang S,Lv C,Liu Y
Mon May 01 00:00:00 EDT 2023
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
Oxidative medicine and cellular longevity
Yang YJ,Wang Y,Deng Y,Liu XQ,Lu J,Peng J,Li J,Zhou YS,Zhu HA,Li B,Qin YH,Peng QH
Wed Jan 18 00:00:00 EST 2023
YY1 (Yin-Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression.
Psychiatry and clinical neurosciences
Lu J,Jin K,Jiao J,Liu R,Mou T,Chen B,Zhang Z,Jiang C,Zhao H,Wang Z,Zhou R,Huang M
Wed Mar 01 00:00:00 EST 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 EDT 2023
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis.
Arteriosclerosis, thrombosis, and vascular biology
Li S,Wang W,Lin L,Yang L,Cai Y,Yang X,Zhang T,Xiao C,Yan H,Gao N,Zhao J
Wed Feb 01 00:00:00 EST 2023
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Advanced biology
Ruan Z,Chi J,Kong Y,Li C,Ruan X,Zhou X,Chen Y,Li Y,Luo Z
Sat Jul 01 00:00:00 EDT 2023
Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m6A-dependent manner.
Clinical immunology (Orlando, Fla.)
Xiang S,Wang Y,Lei D,Luo Y,Peng D,Zong K,Liu Y,Huang Z,Mo S,Pu X,Zheng J,Wu Z
Thu Jun 01 00:00:00 EDT 2023
Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.
Nutrients
Chen K,Wang J,Guo L,Wang J,Yang L,Hu T,Zhao Y,Wang X,Zhu Y
Thu Feb 23 00:00:00 EST 2023
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
Translational lung cancer research
Wang S,Huang Z,Liu Y,Sun H,Zhou Y,Shi J
Fri Mar 31 00:00:00 EDT 2023
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
European journal of pharmacology
Yang Y,Jin Y,Yin L,Liu P,Zhu L,Gao H
Sun Mar 05 00:00:00 EST 2023
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
Journal of cancer research and clinical oncology
Liu F,Wei X,Chen Z,Chen Y,Hu P,Jin Y
Fri Sep 01 00:00:00 EDT 2023
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Molecular medicine reports
Gu C,Gao F,Zhang S,Kang L,Zhang W,Feng X,Liu J,Tian Y,Wei Q,Du Y,Xing Y,Liu Q,Liu S
Wed Feb 01 00:00:00 EST 2023
Pemetrexed induces ROS generation and cellular senescence by attenuating TS-mediated thymidylate metabolism to reverse gefitinib resistance in NSCLC.
Journal of cellular and molecular medicine
Chen Y,Zhang C,Jin S,Li J,Dai J,Zhang Z,Guo R
Sat Jul 01 00:00:00 EDT 2023
Liraglutide abrogates nephrotoxic effects of chemotherapies.
Pharmacological research
Xu C,Lu C,Wang Z,Hu X,Li S,Xie Y,Qiu Y,Cao R,Li Y,Yang J
Wed Mar 01 00:00:00 EST 2023
Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells.
International journal of molecular sciences
Wang X,Wang X,Zhang J,Shan Q,Zhu Y,Xu C,Wang J
Mon Mar 20 00:00:00 EDT 2023
PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.
Journal of virology
Zhai X,Kong N,Wang C,Qin W,Dong S,Zhai H,Yang X,Ye C,Ye M,Li G,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Tong G,Shan T
Tue Jan 31 00:00:00 EST 2023
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Journal of liposome research
Ding H,Wang K,He LQ,Yang XY,Huang HH,Liu WL,Xiao C,Du ZX,Yu L,Zhang W
Thu Jun 01 00:00:00 EDT 2023
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
The Journal of toxicological sciences
Luo J,Liu J,Mou Y,Luo F,Liao Q,Liao Y
Fri Jun 02 00:00:00 EDT 2023
Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect.
PLoS pathogens
Zhang L,Liu W,Wu N,Wang H,Zhang Z,Liu Y,Wang X
Sun Jan 01 00:00:00 EST 2023
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter.
Life science alliance
Akino S,Yasujima T,Yamashiro T,Yuasa H
Wed Feb 01 00:00:00 EST 2023
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
International journal of biological sciences
Zhou H,Zhang Q,Huang W,Zhou S,Wang Y,Zeng X,Wang H,Xie W,Kong H
Tue Apr 18 00:00:00 EDT 2023
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
Clinical and experimental pharmacology & physiology
Zhou X,Liu C,Xia D
Sat Jul 01 00:00:00 EDT 2023
Dickkopf-1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Zheng T,Zhang Y,Zhao Y,Liu F,Dai S,Liu X,Zhang M
Tue Aug 01 00:00:00 EDT 2023
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Metabolites
Yang Y,Zhang Z,Li W,Li L,Zhou Y,Du W
Mon Apr 10 00:00:00 EDT 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 EST 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 EST 2023
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Cell & bioscience
Sui L,Zhao Y,Wang W,Chi H,Tian T,Wu P,Zhang J,Zhao Y,Wei ZK,Hou Z,Zhou G,Wang G,Wang Z,Liu Q
Fri Jan 13 00:00:00 EST 2023
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.
Aging
Shi X,Wu Y,Tang L,Ni H,Xu Y
Tue Mar 28 00:00:00 EDT 2023
Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments.
Frontiers in pharmacology
Xu X,Yu Y,Yang L,Wang B,Fan Y,Ruan B,Zhang X,Dai H,Mei W,Jie W,Zheng S
Tue Mar 21 00:00:00 EDT 2023
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Scientific reports
Jiang Z,Zhang A,Wei W,Li S
Wed May 24 00:00:00 EDT 2023
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Blood
Cheng Q,Wang D,Lai X,Liu Y,Zuo Y,Zhang W,Lei L,Chen J,Liu H,Wang Y,Liu H,Zheng H,Wu D,Xu Y
Thu Mar 23 00:00:00 EDT 2023
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
Chinese medicine
Wu R,Xi Z,Liu M,Ren H,Dai R,Jiang X,Nik Nabil WN,Wang Y,Feng J,Chai Q,Dong Q,Xu H
Sun May 28 00:00:00 EDT 2023
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio)
Haoran S,Zhishan J,Yan M,Ruilin M,Jianjian C,Zejun Y,Jianwen Z,Hui G,Yin Z
Fri Sep 15 00:00:00 EDT 2023
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
European journal of medicinal chemistry
Chen J,Zhao T,He F,Zhong Y,Wang S,Tang Z,Qiu Y,Wu Z,Fang M
Mon Jun 05 00:00:00 EDT 2023
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Autophagy
Cai W,Hu M,Li C,Wu R,Lu D,Xie C,Zhang W,Li T,Shen S,Huang H,Qiu W,Liu Q,Lu Y,Lu Z
Sat Apr 01 00:00:00 EDT 2023
Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy.
Molecular therapy : the journal of the American Society of Gene Therapy
Wu N,Li F,Yang W,Du WW,Awan FM,Zhang C,Lyu J,Misir S,Zeng K,Eshaghi E,Yang BB
Wed Jun 07 00:00:00 EDT 2023
N6-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Translational cancer research
Zheng X,Li S,Yu J,Dai C,Yan S,Chen G,Sun C
Fri Apr 28 00:00:00 EDT 2023
Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency.
iScience
Liu LZ,Liu L,Shi ZH,Bian XL,Si ZR,Wang QQ,Xiang Y,Zhang Y
Fri May 19 00:00:00 EDT 2023
USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail.
Journal of cancer research and clinical oncology
Wei C,Zhao X,Zhang H,Wang L
Fri Sep 01 00:00:00 EDT 2023
The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.
Cell death and differentiation
Wang S,Wang T,Zhang X,Cheng S,Chen C,Yang G,Wang F,Wang R,Zhang Q,Yang D,Zhang Y,Liu S,Qin H,Liu Q,Liu H
Sat Jul 01 00:00:00 EDT 2023
Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation.
Journal of integrative neuroscience
Zhang H,Sun C,He B,Zhang X,Hao H,Hou Y,Li A,Wang Y,Wang Y
Fri Feb 10 00:00:00 EST 2023
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Experimental hematology & oncology
Chen Y,Yang P,Wang J,Gao S,Xiao S,Zhang W,Zhu M,Wang Y,Ke X,Jing H
Tue Mar 07 00:00:00 EST 2023
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Cell reports
Jiang X,Liu K,Jiang H,Yin H,Wang ED,Cheng H,Yuan F,Xiao F,Wang F,Lu W,Peng B,Shu Y,Li X,Chen S,Guo F
Tue Jan 31 00:00:00 EST 2023
Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.
Nature communications
Wang M,Li P,Li Z,da Silva BS,Zheng W,Xiang Z,He Y,Xu T,Cordeiro C,Deng L,Dai Y,Ye M,Lin Z,Zhou J,Zhou X,Ye F,Cunha RA,Chen J,Guo W
Wed Apr 05 00:00:00 EDT 2023
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Psychopharmacology
Liao D,Shangguan D,Wu Y,Chen Y,Liu N,Tang J,Yao D,Shi Y
Mon May 01 00:00:00 EDT 2023
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
International journal of biological macromolecules
Ding Q,Ding C,Liu X,Zheng Y,Zhao Y,Zhang S,Sun S,Peng Z,Liu W
Fri Jun 30 00:00:00 EDT 2023
Exosomal lncRNA HOTAIR induces PDL1+ B cells to impede anti-tumor immunity in colorectal cancer.
Biochemical and biophysical research communications
Xie Z,Xia J,Jiao M,Zhao P,Wang Z,Lin S,Xing Y,Li Y,Lu Z,Zhong Z,Miao C,Zhou P,Qian J,Wang L,Zhang D,Gu J,Chu Y,Liu R
Sun Feb 12 00:00:00 EST 2023
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Life sciences
Wen T,Duan Y,Gao D,Zhang X,Zhang X,Liang L,Yang Z,Zhang P,Zhang J,Sun J,Feng Y,Zheng Q,Han H,Yan X
Tue Aug 01 00:00:00 EDT 2023
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Ecotoxicology and environmental safety
Zhang B,Li H,Wang Y,Li Y,Zhou Z,Hou X,Zhang X,Liu T
Wed Feb 01 00:00:00 EST 2023
Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn.
Stem cells (Dayton, Ohio)
Chen M,Chen X,Li X,Wang J,Wu J,Wang Q,Huang Y,Li Z,Wang L
Thu Jun 15 00:00:00 EDT 2023
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Zhuang MQ,Jiang XL,Liu WD,Xie QH,Wang P,Dong LW,Hu HP,Zhou HB,Zhou YB
Tue Aug 01 00:00:00 EDT 2023
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Cell reports
Fan G,Wang F,Chen Y,Zheng Q,Xiong J,Lv Q,Wu K,Xiong J,Wei L,Li D,Zhang J,Zhang W,Li F
Tue Jan 31 00:00:00 EST 2023
Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway.
Oxidative medicine and cellular longevity
Wang Y,Liang Z,Song W,Qin Y,Todd N,Gao M
Mon Feb 27 00:00:00 EST 2023
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu Y,Mi Y,Wang Y,Meng Q,Xu L,Liu Y,Zhou D,Wang Y,Liang D,Li W,Li N,Hou Y
Mon May 01 00:00:00 EDT 2023
Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.
Acta pharmacologica Sinica
Xu HW,Li WF,Hong SS,Shao JJ,Chen JH,Chattipakorn N,Wu D,Luo W,Liang G
Thu Jun 01 00:00:00 EDT 2023
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Developmental cell
Yi J,Wang L,Du J,Wang M,Shen H,Liu Z,Qin Y,Liu J,Hu G,Xiao R,Ding J,Chen X,Wang H,Huang H,Ouyang G,Liu W
Mon May 08 00:00:00 EDT 2023
FTO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Nature communications
Li B,Xi W,Bai Y,Liu X,Zhang Y,Li L,Bian L,Liu C,Tang Y,Shen L,Yang L,Gu X,Xie J,Zhou Z,Wang Y,Yu X,Wang J,Chao J,Han B,Yao H
Mon Jan 30 00:00:00 EST 2023
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.
Journal of virology
Wang C,Wang T,Hu R,Duan L,Hou Q,Han Y,Dai J,Wang W,Ren S,Liu H,Wang X,Xiao S,Li N,Wang J,Yang Z
Thu Mar 30 00:00:00 EDT 2023
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Acta pharmacologica Sinica
Zhu XX,Wang X,Jiao SY,Liu Y,Shi L,Xu Q,Wang JJ,Chen YE,Zhang Q,Song YT,Wei M,Yu BQ,Fielitz J,Gonzalez FJ,Du J,Qu AJ
Wed Nov 01 00:00:00 EDT 2023
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells.
Nature immunology
Ma S,Sun B,Duan S,Han J,Barr T,Zhang J,Bissonnette MB,Kortylewski M,He C,Chen J,Caligiuri MA,Yu J
Wed Feb 01 00:00:00 EST 2023
COPS3 inhibition promotes cell proliferation blockage and anoikis via regulating PFKFB3 in osteosarcoma cancer cells.
European journal of pharmacology
Zhang F,Li Q,Zhang Y,Li N,Rao M,Li S,Ai Z,Yan S,Tian Z
Sat Jul 15 00:00:00 EDT 2023
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.
The EMBO journal
Elcocks H,Brazel AJ,McCarron KR,Kaulich M,Husnjak K,Mortiboys H,Clague MJ,Urbé S
Mon Jul 03 00:00:00 EDT 2023
TLR2-mediated NF-κB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells.
Veterinary research communications
Xu M,Jin X,Zhang C,Liao H,Wang P,Zhou Y,Song Y,Xia L,Wang L
Thu Jun 01 00:00:00 EDT 2023
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.
Biological trace element research
Wu Y,Shi H,Xu Y,Wen R,Gong M,Hong G,Xu S
Sat Apr 01 00:00:00 EDT 2023
Characterization and mechanisms of radioresistant lung squamous cell carcinoma cell lines.
Thoracic cancer
Pan L,Wu Q,Wang Y,Ma S,Zhang S
Mon May 01 00:00:00 EDT 2023
Hesperidin enhances intestinal barrier function in Caco-2 cell monolayers via AMPK-mediated tight junction-related proteins.
FEBS open bio
Park HY,Yu JH
Wed Mar 01 00:00:00 EST 2023
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
Cellular and molecular life sciences : CMLS
Hu Y,Qi C,Shi J,Tan W,Zhao Z,Xu Y,Wu H,Zhang Z
Thu Mar 23 00:00:00 EDT 2023
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
The journal of gene medicine
Song W,Li Z,Yang K,Gao Z,Zhou Q,Li P
Fri Sep 01 00:00:00 EDT 2023
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Frontiers in immunology
Ding S,Cheng Y,Azad MAK,Dong H,He J,Huang P,Kong X
Tue Mar 07 00:00:00 EST 2023
Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.
Nature communications
Kuang C,Xia M,An G,Liu C,Hu C,Zhang J,Liu Z,Meng B,Su P,Xia J,Guo J,Zhu Y,Liu X,Wu X,Shen Y,Feng X,He Y,Li J,Qiu L,Zhou J,Zhou W
Thu Apr 13 00:00:00 EDT 2023
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
International journal of oral science
Yuan G,Yang S,Yang S
Thu Feb 16 00:00:00 EST 2023
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
The FEBS journal
Wei Y,Xiao G,Xu H,Sun X,Shi Y,Wang F,Kang J,Peng J,Zhou F
Sat Jul 01 00:00:00 EDT 2023
SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.
Virologica Sinica
Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J
Tue Aug 01 00:00:00 EDT 2023
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
Journal of nanobiotechnology
Zhu TT,Wang H,Gu HW,Ju LS,Wu XM,Pan WT,Zhao MM,Yang JJ,Liu PM
Fri Feb 10 00:00:00 EST 2023
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Carcinogenesis
Liu Z,Luo P,Cao K,Hu Q,Hu B,Cui L,Wang X,Shi H,Zhang B,Wang R
Sat Jun 24 00:00:00 EDT 2023
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Acta neuropathologica communications
Cheng K,Wang Y,He Y,Tian Y,Li J,Chen C,Xu X,Wu Z,Yu H,Chen X,Wu Y,Song W,Dong Z,Xu H,Xie P
Mon Apr 03 00:00:00 EDT 2023
Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach.
Journal of gastrointestinal oncology
Shu J,Luo P,Zhang G,Gao Y
Sat Apr 29 00:00:00 EDT 2023
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
The FEBS journal
Kuang H,Sun X,Liu Y,Tang M,Wei Y,Shi Y,Li R,Xiao G,Kang J,Wang F,Peng J,Xu H,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
The Journal of clinical investigation
Yan J,Chen Y,Patel AJ,Warda S,Lee CJ,Nixon BG,Wong EW,Miranda-Román MA,Yang N,Wang Y,Pachai MR,Sher J,Giff E,Tang F,Khurana E,Singer S,Liu Y,Galbo PM,Maag JL,Koche RP,Zheng D,Antonescu CR,Deng L,Li MO,Chen Y,Chi P
Thu Sep 01 00:00:00 EDT 2022
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Neuron
LaForce GR,Farr JS,Liu J,Akesson C,Gumus E,Pinkard O,Miranda HC,Johnson K,Sweet TJ,Ji P,Lin A,Coller J,Philippidou P,Wagner EJ,Schaffer AE
Wed Apr 20 00:00:00 EDT 2022
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Neuron
LaForce GR,Farr JS,Liu J,Akesson C,Gumus E,Pinkard O,Miranda HC,Johnson K,Sweet TJ,Ji P,Lin A,Coller J,Philippidou P,Wagner EJ,Schaffer AE
Wed Apr 20 00:00:00 EDT 2022
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Journal of molecular cell biology
Zheng J,Suo L,Zhou Y,Jia L,Li J,Kuang Y,Cui D,Zhang X,Wu Q
Fri Jan 21 00:00:00 EST 2022
Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models.
Oxidative medicine and cellular longevity
Bao C,He Q,Wang H,Sun Y,Xu Y,Pan Y,Hu Y,Zheng S,Liang S,Luo A,Nahar T,Chen J,Tang H,Han Y
Tue Jun 28 00:00:00 EDT 2022
HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.
Stem cell reviews and reports
Mi X,Jiao W,Yang Y,Qin Y,Chen ZJ,Zhao S
Wed Jun 01 00:00:00 EDT 2022
HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.
Cancer science
Song Q,Wen J,Li W,Xue J,Zhang Y,Liu H,Han J,Ning T,Lu Z
Fri Apr 01 00:00:00 EDT 2022
The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP.
Frontiers in cell and developmental biology
Yue W,Ma J,Xiao Y,Wang P,Gu X,Xie B,Li M
Sat Jul 16 00:00:00 EDT 2022
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Journal of oncology
Yi J,Peng F,Zhao J,Gong X
Tue Feb 08 00:00:00 EST 2022
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Journal of diabetes research
Yu Q,Lin J,Ma Q,Li Y,Wang Q,Chen H,Liu Y,Liu B
Tue May 03 00:00:00 EDT 2022
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
International wound journal
Jiang M,Yakupu A,Guan H,Dong J,Liu Y,Song F,Tang J,Tian M,Niu Y,Lu S
Sat Jan 01 00:00:00 EST 2022
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Theranostics
Liu G,Wang Q,Deng L,Huang X,Yang G,Cheng Q,Guo T,Guo L,Niu C,Yang X,Dong J,Zhang J
Thu Apr 21 00:00:00 EDT 2022
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Journal of applied microbiology
Yong W,Zhao Y,Jiang X,Li P
Tue Feb 01 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
Tue Dec 27 00:00:00 EST 2022
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
European journal of immunology
Christgen S,Place DE,Zheng M,Briard B,Yamamoto M,Kanneganti TD
Tue Feb 01 00:00:00 EST 2022
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Neoplasma
Wang R,Hua L,Ma P,Song Y,Min J,Guo Y,Yang C,Li J,Su H
Thu Sep 01 00:00:00 EDT 2022
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
Antioxidants (Basel, Switzerland)
Sun X,Dong S,Kato H,Kong J,Ito Y,Hirofuji Y,Sato H,Kato TA,Sakai Y,Ohga S,Fukumoto S,Masuda K
Wed Jul 13 00:00:00 EDT 2022
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
PeerJ
Yang Y,Hong S,Lu Y,Wang Q,Wang S,Xun Y
Wed Jan 18 00:00:00 EST 2023
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wuniqiemu T,Teng F,Qin J,Lv Y,Nabijan M,Luo Q,Zhou Y,Cui J,Yi L,Tang W,Zhu X,Wang S,Abduwaki M,Nurahmat M,Wei Y,Dong JC
Thu Sep 01 00:00:00 EDT 2022
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Frontiers in microbiology
Qian Y,Yang Y,Qing W,Li C,Kong M,Kang Z,Zuo Y,Wu J,Yu M,Yang Z
Tue Dec 27 00:00:00 EST 2022
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Free radical biology & medicine
Yu W,Chen C,Zhuang W,Wang W,Liu W,Zhao H,Lv J,Xie D,Wang Q,He F,Xu C,Chen B,Yamamoto T,Koyama H,Cheng J
Sat Jan 01 00:00:00 EST 2022
SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma.
Carcinogenesis
Huang L,Li L,Cheng B,Xing T
Sat Oct 22 00:00:00 EDT 2022
3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress.
Journal of enzyme inhibition and medicinal chemistry
Li Y,Pan Y,Wang L,Wang X,Chu H,Li Y,Mu Y,Sun J
Thu Dec 01 00:00:00 EST 2022
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.
Lung
Shahraki AH,Tian R,Zhang C,Fregien NL,Bejarano P,Mirsaeidi M
Mon Aug 01 00:00:00 EDT 2022
Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice.
The Journal of biological chemistry
Harada N,Kubo K,Onishi T,Kitakaze T,Goto T,Inui H,Yamaji R
Thu Dec 01 00:00:00 EST 2022
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.
Journal of cell science
Iadevaia V,Burke JM,Eke L,Moller-Levet C,Parker R,Locker N
Tue Feb 15 00:00:00 EST 2022
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Phytotherapy research : PTR
Wang L,Wang X,Kong L,Li Y,Huang K,Wu J,Wang C,Sun H,Sun P,Gu J,Luo H,Liu K,Meng Q
Tue Feb 01 00:00:00 EST 2022
RAB27A promotes the proliferation and invasion of colorectal cancer cells.
Scientific reports
Li Q,Zhao H,Dong W,Guan N,Hu Y,Zeng Z,Zhang H,Zhang F,Li Q,Yang J,Xiao W
Sat Nov 12 00:00:00 EST 2022
Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice.
Drug development and industrial pharmacy
Jia S,Jin L,Cheng X,Wu J,Yao X,Shao J,Zhang C,Cen D,Cheng B,Wang J,Chen L,Yao X
Wed Jun 01 00:00:00 EDT 2022
A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology.
Frontiers in pharmacology
Zhao ZH,Xu M,Fu C,Huang Y,Wang TH,Zuo ZF,Liu XZ
Sat Jul 16 00:00:00 EDT 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
International journal of biological sciences
Li J,Yang T,Wang Q,Li Y,Wu H,Zhang M,Qi H,Zhang H,Li J
Tue Jul 12 00:00:00 EDT 2022
Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes.
Nutrients
Tan C,Hong G,Wang Z,Duan C,Hou L,Wu J,Qian W,Han C,Hou X
Sat Nov 12 00:00:00 EST 2022
KLF16 inhibits PEDV replication by activating the type I IFN signaling pathway.
Veterinary microbiology
Dong S,Kong N,Shen H,Li Y,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Tue Nov 01 00:00:00 EDT 2022
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Journal of ethnopharmacology
Li JJ,Wang CM,Wang YJ,Yang Q,Cai WY,Li YJ,Song M,Zang YL,Cui XH,Li Q,Chen Y,Weng XG,Zhu XX
Sun Apr 24 00:00:00 EDT 2022
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Carcinogenesis
Liu Y,Pan L,Li Y,Deng Y,Han X,Fu H,Wang T
Thu May 19 00:00:00 EDT 2022
Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia.
International journal of molecular sciences
Zou W,Zhang J,Zhang K,Peng Z,Xin R,Wang L,Li J
Mon Sep 19 00:00:00 EDT 2022
Paclitaxel-based supramolecular hydrogel loaded with mifepristone for the inhibition of breast cancer metastasis.
Cancer science
Zhao CC,Zhang CG,Sun X,Guo Q,Liu J,Liu Y,Hao YN,Feng G,Yang L,Liu H,Liu J
Tue Feb 01 00:00:00 EST 2022
High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.
European heart journal open
Yang Y,Zeng Q,Gao J,Yang B,Zhou J,Li K,Li L,Wang A,Li X,Liu Z,Luo Q,Zhao Z,Liu B,Xue J,Jiang X,Konerman MC,Zheng L,Xiong C
Thu Sep 01 00:00:00 EDT 2022
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhu D,Wang Z,Zhang G,Ma C,Qiu X,Wang Y,Liu M,Guo X,Chen H,Deng Q,Kang X
Fri Jul 01 00:00:00 EDT 2022
Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.
Frontiers in pharmacology
Guo Z,Duan J,Chen Y,Cai W,Yang C,Yang Z,Liu X,Xu F
Tue Aug 02 00:00:00 EDT 2022
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Experimental neurology
Chen YL,Tong L,Chen Y,Fu CH,Peng JB,Ji LL
Wed Jun 01 00:00:00 EDT 2022
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
Biomedicines
Li T,Liu H,Jiang D,Yang K,Shen J,Feng H,Wang S,Zhang Y,Wang Y,Tang TS
Tue May 17 00:00:00 EDT 2022
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Anatomical record (Hoboken, N.J. : 2007)
Hu JH,Fan P,Zhang LR,Chen CY,Xu J,Huang J,Lu WT,Zhu SJ,Qiu GP,Xu SY,Ran JH,Gan SW
Tue Feb 01 00:00:00 EST 2022
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Oxidative medicine and cellular longevity
Huang Q,Peng M,Gu Y,Wu J,Zhan Y,Deng Z,Chen S,Yang R,Chen J,Xie J
Fri Dec 30 00:00:00 EST 2022
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Journal of agricultural and food chemistry
Xu D,Zhuang L,Gao S,Ma H,Cheng J,Liu J,Liu D,Fu S,Hu G
Wed Nov 23 00:00:00 EST 2022
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Brain sciences
Xin Y,Wang J,Chu T,Zhou Y,Liu C,Xu A
Sat Dec 17 00:00:00 EST 2022
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.
Journal of cellular and molecular medicine
Yang F,Liu XQ,He JZ,Xian SP,Yang PF,Mai ZY,Li M,Liu Y,Zhang XD
Fri Apr 01 00:00:00 EDT 2022
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Journal of immunology research
Lin D,Zhang M,Luo C,Wei P,Cui K,Chen Z
Tue Jun 28 00:00:00 EDT 2022
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
Current medical science
Jie L,Hong RT,Zhang YJ,Sha LL,Chen W,Ren XF
Wed Jun 01 00:00:00 EDT 2022
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.
Cell metabolism
Pan RY,He L,Zhang J,Liu X,Liao Y,Gao J,Liao Y,Yan Y,Li Q,Zhou X,Cheng J,Xing Q,Guan F,Zhang J,Sun L,Yuan Z
Tue Apr 05 00:00:00 EDT 2022
Post-Injury Buprenorphine Administration Is Associated with Long-Term Region-Specific Glial Alterations in Rats.
Pharmaceutics
Ryu J,Jeizan P,Ahmed S,Ehsan S,Jose J,Regan S,Gorse K,Kelliher C,Lafrenaye A
Wed Sep 28 00:00:00 EDT 2022
Circ_0060731 mediated miR-21-5p-PDCD4/ESR1 pathway to induce apoptosis of placental trophoblasts in intrahepatic cholestasis of pregnancy.
Tissue & cell
Feng F,Lei L,Liao J,Huang X,Shao Y
Wed Jun 01 00:00:00 EDT 2022
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Molecular medicine (Cambridge, Mass.)
Xiao J,Zeng W,Zhang P,Zhou Y,Fang Q
Tue Sep 06 00:00:00 EDT 2022
Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis.
International journal of general medicine
Wang C,Chen Z,Yang X,Zhang W,Zhou J,Zhang H,Ding X,Ye J,Wu H,Wu Y,Zheng Y,Song X
Fri Mar 11 00:00:00 EST 2022
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
Journal of virology
Cao J,Liu S,Liu M,Wang S,Bi Z,Fan W,Shi Z,Song S,Yan L
Wed Aug 10 00:00:00 EDT 2022
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Frontiers in pharmacology
Bao N,Cheng L,Wang Y,Peng Z,Wang Z,Chen S
Sat Dec 10 00:00:00 EST 2022
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Frontiers in endocrinology
Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M
Tue Jan 17 00:00:00 EST 2023
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
International journal of molecular sciences
Wu Z,Zhou G,Wang H,Yao P
Mon Apr 18 00:00:00 EDT 2022
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Food & function
Ru M,Wang W,Zhai Z,Wang R,Li Y,Liang J,Kothari D,Niu K,Wu X
Mon Jul 18 00:00:00 EDT 2022
Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.
Molecular medicine (Cambridge, Mass.)
Wang B,Gao J,Zhao Z,Zhong X,Cui H,Hou H,Zhang Y,Zheng J,Di J,Liu Y
Wed Sep 07 00:00:00 EDT 2022
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
International immunopharmacology
Yi N,Mi Y,Xu X,Li N,Chen B,Yan K,Tan K,Zhang B,Wang L,Kuang G,Lu M
Thu Dec 01 00:00:00 EST 2022
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Food & function
Wang N,Feng BN,Hu B,Cheng YL,Guo YH,Qian H
Mon Feb 21 00:00:00 EST 2022
Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.
Molecular therapy. Methods & clinical development
Chandler RJ,Di Pasquale G,Sloan JL,McCoy S,Hubbard BT,Kilts TM,Manoli I,Chiorini JA,Venditti CP
Thu Dec 08 00:00:00 EST 2022
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Science advances
Zuo Y,He J,Liu S,Xu Y,Liu J,Qiao C,Zang L,Sun W,Yuan Y,Zhang H,Chen X,Jin L,Miao Y,Huang F,Ren T,Wang J,Qian F,Zhu C,Zhang W,Liu Y,Xu G,Ma F,Zheng H
Fri Apr 08 00:00:00 EDT 2022
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hao M,Ding C,Peng X,Chen H,Dong L,Zhang Y,Chen X,Liu W,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response.
Frontiers in immunology
Zhang H,Lu D,Zhang Y,Zhao G,Raheem A,Chen Y,Chen X,Hu C,Chen H,Yang L,Guo A
Wed Sep 28 00:00:00 EDT 2022
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.
PLoS biology
Porman AM,Roberts JT,Duncan ED,Chrupcala ML,Levine AA,Kennedy MA,Williams MM,Richer JK,Johnson AM
Tue Nov 01 00:00:00 EDT 2022
Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice.
Evidence-based complementary and alternative medicine : eCAM
Liu M,Jia H,He Y,Huan Y,Kong Z,Xu N,Cao X,Duan Y,Li Z,Yang L,Wei WP,Wang L,Li L
Sat Jul 16 00:00:00 EDT 2022
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Stem cell research & therapy
Bai F,Duan J,Yang D,Lai X,Zhu X,He X,Hu A
Thu Sep 08 00:00:00 EDT 2022
Construction and validation of a prognostic model with RNA binding protein-related mRNAs for the HBV-related hepatocellular carcinoma patients.
Frontiers in oncology
Xu S,Liu H,Tian R,Xie J,Chen S,Luo J,Zhu H,Wang Y,Li Z
Tue Oct 11 00:00:00 EDT 2022
Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs.
Frontiers in nutrition
Li Y,Bao X,Yang F,Tian J,Su W,Yin J,Yao K,Li T,Yin Y
Sat Jul 16 00:00:00 EDT 2022
M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice.
Theranostics
Li Y,Liu Z,Song Y,Pan JJ,Jiang Y,Shi X,Liu C,Ma Y,Luo L,Mamtilahun M,Shi Z,Khan H,Xie Q,Wang Y,Tang Y,Zhang Z,Yang GY
Tue May 17 00:00:00 EDT 2022
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Cell death discovery
Yu T,Liu Y,Xue J,Sun X,Zhu D,Ma L,Guo Y,Jin T,Cao H,Chen Y,Zhu T,Li X,Liang H,Du Z,Shan H
Sat Jul 09 00:00:00 EDT 2022
Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis.
Frontiers in cell and developmental biology
Thalla DG,Rajwar AC,Laurent AM,Becher JE,Kainka L,Lautenschläger F
Fri Aug 05 00:00:00 EDT 2022
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Frontiers in immunology
Chen Y,He J,Chen R,Wang Z,Dai Z,Liang X,Wu W,Luo P,Zhang J,Peng Y,Zhang N,Liu Z,Zhang L,Zhang H,Cheng Q
Fri Aug 26 00:00:00 EDT 2022
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
ACS nano
Rong R,Zhou X,Liang G,Li H,You M,Liang Z,Zeng Z,Xiao H,Ji D,Xia X
Tue Dec 27 00:00:00 EST 2022
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Developmental and comparative immunology
Yu G,Yu H,Yang Q,Wang J,Fan H,Liu G,Wang L,Bello BK,Zhao P,Zhang H,Dong J
Tue Feb 01 00:00:00 EST 2022
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Acta pharmacologica Sinica
Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ
Tue Feb 01 00:00:00 EST 2022
27-hydroxycholesterol linked high cholesterol diet to lung adenocarcinoma metastasis.
Oncogene
Li X,Chen H,Zhang L,Chen L,Wei W,Gao S,Xue Q,Li Y,Wang B,Li J,Gao Y,Lin Y
Sun May 01 00:00:00 EDT 2022
Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.
Biochemical pharmacology
Song YC,Liu CT,Lee HJ,Yen HR
Tue Mar 01 00:00:00 EST 2022
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Journal of virology
Dong S,Kong N,Zhang Y,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed May 25 00:00:00 EDT 2022
Dabie bandavirus Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry.
Journal of virology
Liu H,Liu S,Liu Z,Gao X,Xu L,Huang M,Su Y,Wang Z,Wang T
Wed Jul 27 00:00:00 EDT 2022
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
Li X,Chen H,Zhang Z,Duan J,Hua R,Li X,Yang L,Cheng J,Li Q
Thu Dec 01 00:00:00 EST 2022
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Nutrients
Shi JZ,Zheng XM,Zhou YF,Yun LY,Luo DM,Hao JJ,Liu PF,Zhang WK,Xu JK,Yan Y,Xie XM,He YY,Pang XB
Wed Aug 03 00:00:00 EDT 2022
Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.
Molecular biology reports
Ma Y,Fan P,Zhao R,Zhang Y,Wang X,Cui W
Sun May 01 00:00:00 EDT 2022
Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension.
Frontiers in endocrinology
Ma H,Wang K,Lai B,Zhang X,Lv Y,Li R
Mon Jan 02 00:00:00 EST 2023
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Cancer letters
Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y
Tue Nov 01 00:00:00 EDT 2022
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
BMC molecular and cell biology
Zhu Z,Zhao Z,Chen X,Chu Z,He Y,Tan Y,Zhou J,Tang C
Thu Sep 29 00:00:00 EDT 2022
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Neurochemical research
Liu H,He S,Wang J,Li C,Liao Y,Zou Q,Chen R
Wed Jun 01 00:00:00 EDT 2022
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Bioorganic chemistry
Li T,Chen Y,Tan P,Shi H,Huang Z,Cai T,Cheng Y,Du Y,Fu W
Sun May 01 00:00:00 EDT 2022
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
Acta pharmacologica Sinica
He JY,Hong Q,Chen BX,Cui SY,Liu R,Cai GY,Guo J,Chen XM
Tue Feb 01 00:00:00 EST 2022
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Cell death & disease
Wang R,Wen P,Yang G,Feng Y,Mi Y,Wang X,Zhu S,Chen YQ
Tue Jul 19 00:00:00 EDT 2022
Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.
Nature structural & molecular biology
Tartour K,Andriani F,Folco EG,Letkova D,Schneider R,Saidi I,Sato T,Welz PS,Benitah SA,Allier C,Padmanabhan K
Wed Jun 01 00:00:00 EDT 2022
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Frontiers in nutrition
Dai YJ,Liu WB,Abasubong KP,Zhang DD,Li XF,Xiao K,Wang X,Jiang GZ
Sat Jul 16 00:00:00 EDT 2022
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Toxicology
Tang L,Yu J,Zhuge S,Chen H,Zhang L,Jiang G
Mon Aug 01 00:00:00 EDT 2022
Umbilical Cord Mesenchymal Stem Cells Ameliorate Kidney Injury in MRL/Ipr Mice Through the TGF-β1 Pathway.
Frontiers in cell and developmental biology
Huang C,Meng M,Li S,Liu S,Li L,Su Y,Gao H,He S,Zhao Y,Zhang M,Hou Z,Wang W,Wang X
Sat Jul 16 00:00:00 EDT 2022
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Phytotherapy research : PTR
Cheng L,Shi L,He C,Wang C,Lv Y,Li H,An Y,Dai H,Duan Y,Zhang H,Huang Y,Fu W,Meng Y,Zhao B
Wed Jun 01 00:00:00 EDT 2022
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Molecules (Basel, Switzerland)
Luo JF,Zhou H,Lio CK
Thu Sep 22 00:00:00 EDT 2022
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Biological trace element research
Jiang N,Xu W,Zhang Z,Jin H,Yang Y,Zhang J,Xu H
Tue Feb 01 00:00:00 EST 2022
Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.
Veterinary research
Wen Y,Chen Z,Tian Y,Yang M,Dong Q,Yang Y,Ding H
Thu Aug 04 00:00:00 EDT 2022
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
Aging
Xiao Y,Xiang JW,Gao Q,Bai YY,Huang ZX,Hu XH,Wang L,Li DW
Wed Aug 10 00:00:00 EDT 2022
Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li B,Chen X,Qiu W,Zhao R,Duan J,Zhang S,Pan Z,Zhao S,Guo Q,Qi Y,Wang W,Deng L,Ni S,Sang Y,Xue H,Liu H,Li G
Wed Jun 01 00:00:00 EDT 2022
Effect of Xiongmatang Extract on Behavioral and TRPV1-CGRP/CGRP-R Pathway in Rats With Migraine.
Frontiers in pharmacology
Liu D,Chang L,Wang J,Zhu Q,Jiang N,Azhar M,Ahmed A,Zeng G
Fri Apr 01 00:00:00 EDT 2022
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Cell death & disease
Zhang T,Wang Y,Yu H,Zhang T,Guo L,Xu J,Wei X,Wang N,Wu Y,Wang X,Huang L
Thu Jan 20 00:00:00 EST 2022
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Cell death & disease
Zhang T,Wang Y,Yu H,Zhang T,Guo L,Xu J,Wei X,Wang N,Wu Y,Wang X,Huang L
Thu Jan 20 00:00:00 EST 2022
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Food & function
Zeng X,Ren D,Li D,Du H,Yang X
Mon Oct 17 00:00:00 EDT 2022
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Molecular therapy. Nucleic acids
Zeng L,Jiang H,Ashraf GM,Liu J,Wang L,Zhao K,Liu M,Li Z,Liu R
Tue Mar 08 00:00:00 EST 2022
Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification.
Journal of the American Society of Nephrology : JASN
Miyazaki-Anzai S,Keenan AL,Blaine J,Miyazaki M
Mon Aug 01 00:00:00 EDT 2022
Fabrication of SA/Gel/C scaffold with 3D bioprinting to generate micro-nano porosity structure for skin wound healing: a detailed animal in vivo study.
Cell regeneration (London, England)
Niu C,Wang L,Ji D,Ren M,Ke D,Fu Q,Zhang K,Yang X
Sun May 01 00:00:00 EDT 2022
CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1.
Journal of agricultural and food chemistry
Cheng J,Xu D,Chen L,Guo W,Hu G,Liu J,Fu S
Wed Sep 14 00:00:00 EDT 2022
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
American journal of respiratory and critical care medicine
Cui H,Xie N,Banerjee S,Dey T,Liu RM,Antony VB,Sanders YY,Adams TS,Gomez JL,Thannickal VJ,Kaminski N,Liu G
Mon Aug 15 00:00:00 EDT 2022
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Nature metabolism
Liu Q,Zhu F,Liu X,Lu Y,Yao K,Tian N,Tong L,Figge DA,Wang X,Han Y,Li Y,Zhu Y,Hu L,Ji Y,Xu N,Li D,Gu X,Liang R,Gan G,Wu L,Zhang P,Xu T,Hu H,Hu Z,Xu H,Ye D,Yang H,Li B,Tong X
Sun May 01 00:00:00 EDT 2022
GDF15 negatively regulates RGS16 to impair hepatic lipid metabolism in male mice offspring conceived by in vitro fertilization.
American journal of translational research
Liu J,Zhu Y,Zhu D,Shi Y,Lu L,Li W,Li L,Zhou X,Zhang P,Yang H,Li M,Wang B,Sun M
Sat Nov 19 00:00:00 EST 2022
Transcriptome Analysis of Protection by Dendrobium Nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice.
Biomedicines
Huang X,Yang S,Sun J,Li X,Zhou SY,Shi JS,Liu J,Wu Q
Thu Nov 03 00:00:00 EDT 2022
PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages.
Cancer letters
Xu Y,Lu J,Tang Y,Xie W,Zhang H,Wang B,Zhang S,Hou W,Zou C,Jiang P,Zhang W
Thu Mar 31 00:00:00 EDT 2022
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Journal of oncology
Chen X,Zhang L,Geng J,Chen Z,Cui X
Sat Jul 16 00:00:00 EDT 2022
Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1-Adiponectin Axis.
Frontiers in endocrinology
Ye T,Zhang J,Wu D,Shi J,Kuang Z,Ma Y,Xu Q,Chen B,Kan C,Sun X,Han F
Wed Jul 06 00:00:00 EDT 2022
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hu Q,Zuo T,Deng L,Chen S,Yu W,Liu S,Liu J,Wang X,Fan X,Dong Z
Wed Jul 20 00:00:00 EDT 2022
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
International journal of molecular sciences
Cheng M,Yu H,Kong Q,Wang B,Shen L,Dong D,Sun L
Tue Jan 25 00:00:00 EST 2022
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Frontiers in pharmacology
Shen B,Zhang R,Yang G,Peng Y,Nie Q,Yu H,Dong W,Chen B,Song C,Tian Y,Qin L,Shu J,Hong S,Li L
Sat Sep 24 00:00:00 EDT 2022
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Pharmaceutical biology
Xia Y,Lu YW,Hao RJ,Yu GR
Thu Dec 01 00:00:00 EST 2022
Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhai Y,Sun J,Sun C,Zhao H,Li X,Yao J,Su J,Xu X,Xu X,Hu J,Daglia M,Han B,Kai G
Tue Nov 01 00:00:00 EDT 2022
Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.
Journal of pharmacological sciences
Takaba M,Iwaki T,Arakawa T,Ono T,Maekawa Y,Umemura K
Fri Jul 01 00:00:00 EDT 2022
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Molecular metabolism
Chen X,Liu Q,Chen Y,Wang L,Yang R,Zhang W,Pan X,Zhang S,Chen C,Wu T,Xia J,Cheng B,Chen X,Ren X
Tue Nov 01 00:00:00 EDT 2022
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Acta pharmacologica Sinica
Chen YQ,Song HY,Zhou ZY,Ma J,Luo ZY,Zhou Y,Wang JY,Liu S,Han XH
Wed Jun 01 00:00:00 EDT 2022
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Advanced healthcare materials
Guo S,Yao M,Zhang D,He Y,Chang R,Ren Y,Guan F
Tue Feb 01 00:00:00 EST 2022
Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.
Evidence-based complementary and alternative medicine : eCAM
Hou J,Wang L,Wang C,Ma R,Wang Z,Xiao H,Zeng D,Ling L,Wang Y
Sat Oct 22 00:00:00 EDT 2022
Glucosamine delays the progression of osteoporosis in senile mice by promoting osteoblast autophagy.
Nutrition & metabolism
Su W,Lv C,Huang L,Zheng X,Yang S
Tue Nov 08 00:00:00 EST 2022
Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.
Heliyon
Ding X,Yang X,Zhao Y,Wang Y,Fei J,Niu Z,Dong X,Wang X,Liu B,Li H,Hao X,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Anti-cancer drugs
Tan X,Song X,Fan B,Li M,Zhang A,Pei L
Sat Oct 01 00:00:00 EDT 2022
Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.
Cancer cell international
Zhou J,Wang C,Liu Y,Cui D,Wang Z,Jiang Y,Gao L
Thu Nov 17 00:00:00 EST 2022
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Neuropharmacology
Qiu J,Chen Y,Zhuo J,Zhang L,Liu J,Wang B,Sun D,Yu S,Lou H
Fri Apr 01 00:00:00 EDT 2022
XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway.
International journal of molecular medicine
Jiang H,Jiang Q,He Y,Li X,Xu Y,Liu X
Tue Mar 01 00:00:00 EST 2022
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
Journal of Zhejiang University. Science. B
Yu M,Zhao Q,Li J,Xu F,Zhang Z,Liu Y,Dai L,Zhang B,Zhang J,Zhang J
Mon Sep 19 00:00:00 EDT 2022
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Ecotoxicology and environmental safety
Zhao H,Zhu Y,Zhao Y,Wang T,Li H,Yang J,Cheng X,Wang J,Wang J
Thu Dec 01 00:00:00 EST 2022
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
Brain research bulletin
Yu Z,Liu Y,Li Y,Zhang J,Peng J,Gong J,Xia Y,Wang L
Tue Feb 01 00:00:00 EST 2022
Construction of Attenuated Strains for Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) via Reverse Genetic System.
Viruses
Lei Y,Xiong Y,Tao D,Wang T,Chen T,Du X,Cao G,Tu J,Dai J
Sat Aug 06 00:00:00 EDT 2022
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Journal of ethnopharmacology
Li Y,Fu Y,Sun J,Shen J,Liu F,Ning B,Lu Z,Wei L,Jiang X
Mon Jan 10 00:00:00 EST 2022
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
International immunopharmacology
Li T,Bai J,Du Y,Tan P,Zheng T,Chen Y,Cheng Y,Cai T,Huang M,Fu W,Wen J
Fri Jul 01 00:00:00 EDT 2022
Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.
In vitro cellular & developmental biology. Animal
Wang R,Yang Z,Liang L,Feng X,Che B,Zhang X,Zheng Q,Yan X,Han H
Tue Feb 01 00:00:00 EST 2022
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Virus research
Wang Y,He J,Mo M,Cai Q,Wu W,Yuan M,Yang K
Sat Jan 15 00:00:00 EST 2022
Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype.
Frontiers in neuroscience
Sun Y,Jin MF,Li L,Liu Y,Wang D,Ni H
Wed Apr 13 00:00:00 EDT 2022
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Food science & nutrition
Cui J,Zong W,Zhao N,Yuan R
Mon Aug 01 00:00:00 EDT 2022
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis.
European journal of histochemistry : EJH
Li J,Kang J,Liu W,Liu J,Pan G,Mao A,Zhang Q,Lu J,Ding J,Li H
Tue Oct 25 00:00:00 EDT 2022
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Autophagy
Han T,Wang P,Wang Y,Xun W,Lei J,Wang T,Lu Z,Gan M,Zhang W,Yu B,Wang JB
Wed Jun 01 00:00:00 EDT 2022
YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.
Journal of experimental & clinical cancer research : CR
Li W,Ye K,Li X,Liu X,Peng M,Chen F,Xiong W,Wang Y,Zhu L
Wed Aug 17 00:00:00 EDT 2022
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Virus research
Chen X,Li Z,Wang S,Tong G,Chen K,Zhao Y
Sun Oct 02 00:00:00 EDT 2022
Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo.
Bioelectromagnetics
Zhou J,Wang J,Qu M,Huang X,Yin L,Liao Y,Huang F,Ning P,Zhong P,Zeng Y
Sat Oct 01 00:00:00 EDT 2022
In Vivo Visualization of RNAi Efficiency Using a Pumilio/FBF Protein-Based Reporter.
Analytical chemistry
Shi X,Hu C,Jiang Y,Lei Z,Zhang C,Zhang B,Wang F
Tue Nov 08 00:00:00 EST 2022
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis.
Nature communications
Wu M,Zhang X,Zhang W,Chiou YS,Qian W,Liu X,Zhang M,Yan H,Li S,Li T,Han X,Qian P,Liu S,Pan Y,Lobie PE,Zhu T
Wed Mar 16 00:00:00 EDT 2022
Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/RORγT expression and reversing Treg/Th17 cell imbalance.
International immunopharmacology
Wang C,Huang CF,Li M
Tue Feb 01 00:00:00 EST 2022
Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis.
International journal of molecular sciences
Wan Y,Liu Z,Wu A,Khan AH,Zhu Y,Ding S,Li X,Zhao Y,Dai X,Zhou J,Liu J,Li Y,Gong X,Liu M,Tian XL
Mon Mar 07 00:00:00 EST 2022
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Cell biochemistry and biophysics
Bandela M,Suryadevara V,Fu P,Reddy SP,Bikkavilli K,Huang LS,Dhavamani S,Subbaiah PV,Singla S,Dudek SM,Ware LB,Ramchandran R,Natarajan V
Tue Mar 01 00:00:00 EST 2022
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Frontiers in pharmacology
Zhang MX,Huang XY,Song Y,Xu WL,Li YL,Li C
Thu Feb 02 00:00:00 EST 2023
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.
Journal for immunotherapy of cancer
Zhao S,Wang Y,Yang N,Mu M,Wu Z,Li H,Tang X,Zhong K,Zhang Z,Huang C,Cao T,Zheng M,Wang G,Nie C,Yang H,Guo G,Zhou L,Zheng X,Tong A
Wed Jun 01 00:00:00 EDT 2022
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Frontiers in pharmacology
Lou K,Sun P,Zhang C,Jiang Q,Pang S
Tue Nov 29 00:00:00 EST 2022
NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.
Scientific reports
Li C,Meng J,Zhang T
Fri Jun 10 00:00:00 EDT 2022
LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells.
Carcinogenesis
Zhang Z,Liu T,Cheng C,Wang J,Wang C,Huang H,Li Y
Sat Dec 31 00:00:00 EST 2022
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Science advances
Miao H,Wu F,Li Y,Qin C,Zhao Y,Xie M,Dai H,Yao H,Cai H,Wang Q,Song X,Li L
Fri Dec 23 00:00:00 EST 2022
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Journal of nanobiotechnology
Su L,Sun Z,Qi F,Su H,Qian L,Li J,Zuo L,Huang J,Yu Z,Li J,Chen Z,Zhang S
Wed Jul 20 00:00:00 EDT 2022
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology
Li X,Chu Y,Ma R,Dou M,Li S,Song Y,Lv Y,Zhu L
Thu Dec 15 00:00:00 EST 2022
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Reproductive biology
Xia J,Wu S,Wu G,Yang J
Thu Sep 01 00:00:00 EDT 2022
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
Canadian journal of physiology and pharmacology
Liu H,Ru NY,Cai Y,Lyu Q,Guo CH,Zhou Y,Li SH,Cheng JH,Chang JR,Ma J,Su XL
Fri Apr 01 00:00:00 EDT 2022
Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway.
Journal of ethnopharmacology
Mu W,Ao J,Li Y,Zhang J,Duan C
Wed Oct 05 00:00:00 EDT 2022
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Theranostics
Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T
Thu Mar 10 00:00:00 EST 2022
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
Frontiers in oncology
Zhang Y,Cheng J,Zhong C,Xia Q,Li Y,Chen P,Fan X,Mao Q,Lin H,Hong D
Sat Jul 16 00:00:00 EDT 2022
Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.
Frontiers in pharmacology
Zhu W,Wang Y,Liu C,Wu Y,Li Y,Wang Y
Fri Nov 25 00:00:00 EST 2022
Prefrontal GABAA(δ)R Promotes Fear Extinction through Enabling the Plastic Regulation of Neuronal Intrinsic Excitability.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Pan HQ,Liu XX,He Y,Zhou J,Liao CZ,You WJ,Jiang SY,Qin X,Chen WB,Fei EK,Zhang WH,Pan BX
Wed Jul 20 00:00:00 EDT 2022
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
International journal of biological macromolecules
Wang Y,Wang Q,Duan L,Li X,Yang W,Huang T,Kong M,Guan F,Ma S
Thu Dec 01 00:00:00 EST 2022
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.
Nature cell biology
Huang D,Wang Y,Thompson JW,Yin T,Alexander PB,Qin D,Mudgal P,Wu H,Liang Y,Tan L,Pan C,Yuan L,Wan Y,Li QJ,Wang XF
Tue Feb 01 00:00:00 EST 2022
Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.
Cell death & disease
Xie Q,Zhang M,Mao X,Xu M,Liu S,Shang D,Xu Y,Chen R,Guan Y,Huang X,Zent R,Pozzi A,Hao CM
Thu Dec 15 00:00:00 EST 2022
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Frontiers in pharmacology
Zhu Z,Wang X,Song Z,Zuo X,Ma Y,Zhang Z,Ju C,Liang Z,Li K,Hu X,Wang Z
Fri Sep 30 00:00:00 EDT 2022
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
Journal of medicinal chemistry
Pan S,Zhang L,Luo X,Nan J,Yang W,Bin H,Li Y,Huang Q,Wang T,Pan Z,Mu B,Wang F,Tian C,Liu Y,Li L,Yang S
Thu Feb 10 00:00:00 EST 2022
Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation.
The Journal of biological chemistry
Huang K,Jia Z,Li H,Peng Y,Chen X,Luo N,Song T,Wang Y,Shi X,Kuang S,Yang G
Sat Oct 01 00:00:00 EDT 2022
Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis.
The journal of physiological sciences : JPS
Jiang C,Li H,Liu F,Shi L,Liu J,Li Y
Thu May 12 00:00:00 EDT 2022
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Scientific reports
Sun L,Yuan H,Zhao G
Tue Nov 22 00:00:00 EST 2022
Luteolin ameliorates hypoxia-induced pulmonary hypertension via regulating HIF-2α-Arg-NO axis and PI3K-AKT-eNOS-NO signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ji L,Su S,Xin M,Zhang Z,Nan X,Li Z,Lu D
Thu Sep 01 00:00:00 EDT 2022
Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells.
Journal of gastrointestinal oncology
He Y,Li Y,Liang T,Mo S,Liao Y,Chen Z,Zhao S,Ran Q,Han C,Hoa PTT
Wed Jun 01 00:00:00 EDT 2022
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
International journal of molecular sciences
Usman M,Li Y,Ke Y,Chhetri G,Islam MA,Wang Z,Li X
Thu Apr 28 00:00:00 EDT 2022
An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.
Cell reports
Li Y,Wei JY,Liu H,Wang KJ,Jin SN,Su ZK,Wang HJ,Shi JX,Li B,Shang DS,Fang WG,Qin XX,Zhao WD,Chen YH
Tue Apr 12 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Nature communications
Lim RG,Al-Dalahmah O,Wu J,Gold MP,Reidling JC,Tang G,Adam M,Dansu DK,Park HJ,Casaccia P,Miramontes R,Reyes-Ortiz AM,Lau A,Hickman RA,Khan F,Paryani F,Tang A,Ofori K,Miyoshi E,Michael N,McClure N,Flowers XE,Vonsattel JP,Davidson S,Menon V,Swarup V,Fraenkel E,Goldman JE,Thompson LM
Wed Dec 21 00:00:00 EST 2022
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
Cell reports
Wang Y,Wang Y,Ding L,Ren X,Wang B,Wang L,Zhao S,Yue X,Wu Z,Li C,Liang X,Ma C,Gao L
Tue Nov 29 00:00:00 EST 2022
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.
Cancer & metabolism
Okanishi H,Ohgaki R,Xu M,Endou H,Kanai Y
Thu Nov 10 00:00:00 EST 2022
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
Bioengineered
Cao W,Lei S,Zeng Z,Xiao C,Sun B,Xie P,Li Y,Luo D,Yu W
Sun May 01 00:00:00 EDT 2022
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy
Wang X,Zheng S,Yang F,Zhang W,Zhao D,Xue X,Lin Q,He Y,Hu G,Hu Y
Wed Mar 02 00:00:00 EST 2022
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Guan J,Guan B,Shang H,Peng J,Yang H,Lin J
Sat Oct 01 00:00:00 EDT 2022
Role of SLC39A6 in the development and progression of liver cancer.
Oncology letters
Wan Z,Wang X
Tue Mar 01 00:00:00 EST 2022
An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups.
Frontiers in pharmacology
Lin H,Yang M,Li C,Lin B,Deng X,He H,Zhou R
Tue Mar 08 00:00:00 EST 2022
Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice.
Frontiers in aging neuroscience
Xue Z,Shui M,Lin X,Sun Y,Liu J,Wei C,Wu A,Li T
Tue Apr 05 00:00:00 EDT 2022
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Brain research bulletin
Zhou Y,Peng L,Li Y,Zhao Y
Sat Jan 01 00:00:00 EST 2022
Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cao L,Zhou S,Qiu X,Qiu S
Thu Sep 01 00:00:00 EDT 2022
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Experimental cell research
Liu Y,Li Q,Geng L,Zhou X,Zhou X,Dong Y,Zhang Y
Sat Oct 01 00:00:00 EDT 2022
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Frontiers in pharmacology
Wu X,Zhao K,Fang X,Lu F,Cheng P,Song X,Zhang W,Yao C,Zhu J,Chen H
Tue Apr 05 00:00:00 EDT 2022
Sleeve gastrectomy suppresses hepatic de novo cholesterogenesis and improves hepatic cholesterol accumulation in obese rats with type 2 diabetes mellitus.
Nutrition (Burbank, Los Angeles County, Calif.)
Chen F,Liu B
Tue Feb 01 00:00:00 EST 2022
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance.
Open biology
Wang W,Li H,Huang M,Wang X,Li W,Qian X,Jing L
Sat Oct 01 00:00:00 EDT 2022
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway.
Journal of cellular and molecular medicine
Chen P,Zhou J,Ruan A,Zeng L,Liu J,Wang Q
Tue Feb 01 00:00:00 EST 2022
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Brain : a journal of neurology
Li S,Li J,Liu J,Wang J,Li X,Huo Y,Li Y,Liu Y,Li M,Xiao X,Luo XJ
Mon Apr 18 00:00:00 EDT 2022
CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma.
Cell communication and signaling : CCS
Yan X,Kang D,Lin Y,Qi S,Jiang C
Mon Jan 03 00:00:00 EST 2022
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
PPARγ Alleviates Sepsis-Induced Liver Injury by Inhibiting Hepatocyte Pyroptosis via Inhibition of the ROS/TXNIP/NLRP3 Signaling Pathway.
Oxidative medicine and cellular longevity
Li Z,Liu T,Feng Y,Tong Y,Jia Y,Wang C,Cui R,Qu K,Liu C,Zhang J
Fri Mar 18 00:00:00 EDT 2022
High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma.
Cancer medicine
Qin X,Ni Z,Jiang J,Liu X,Dong X,Li M,Miao K,Rao S,Zhang W,Cai K
Sat Oct 01 00:00:00 EDT 2022
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Journal of virology
Dong S,Kong N,Wang C,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed Jul 13 00:00:00 EDT 2022
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Journal of virology
Dong S,Kong N,Wang C,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed Jul 13 00:00:00 EDT 2022
Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate.
Nature metabolism
Zhao M,Yao P,Mao Y,Wu J,Wang W,Geng C,Cheng J,Du W,Jiang P
Tue Feb 01 00:00:00 EST 2022
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Environmental toxicology and pharmacology
Xu Q,Zhou L,Ri H,Li X,Zhang X,Qi W,Ye L
Tue Nov 01 00:00:00 EDT 2022
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Cell & bioscience
Si M,Song Y,Wang X,Wang D,Liu X,Qu X,Song Z,Yu X
Sun Oct 09 00:00:00 EDT 2022
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Cellular signalling
Shen J,Meng Y,Wang K,Gao M,Du J,Wang J,Li Z,Zuo D,Wu Y
Fri Apr 01 00:00:00 EDT 2022
Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis.
Biochemical and biophysical research communications
Li L,Hu G,Xie R,Yang J,Shi X,Jia Z,Qu X,Wang M,Wu Y
Sat Jun 25 00:00:00 EDT 2022
Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways.
Frontiers in pharmacology
Wang RR,Yuan TY,Chen D,Chen YC,Sun SC,Wang SB,Kong LL,Fang LH,Du GH
Sat Jul 16 00:00:00 EDT 2022
Spatial Training Attenuates Long-Term Alzheimer's Disease-Related Pathogenic Processes in APP/PS1 Mice.
Journal of Alzheimer's disease : JAD
Zhao Y,Bao J,Liu W,Gong X,Liang Z,Li W,Wu M,Xiao Y,Sun B,Wang X,Wang JZ,Wang J,Shu X
Thu Mar 03 00:00:00 EST 2022
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Cell death & disease
Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G
Thu Oct 06 00:00:00 EDT 2022
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Stem cell research & therapy
Zhang Y,Le X,Zheng S,Zhang K,He J,Liu M,Tu C,Rao W,Du H,Ouyang Y,Li C,Wu D
Wed Apr 27 00:00:00 EDT 2022
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
Molecular cell
Shi Z,Ge X,Li M,Yin J,Wang X,Zhang J,Chen D,Li X,Wang X,Ji J,You Y,Qian X
Thu Oct 20 00:00:00 EDT 2022
Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS.
International journal of molecular sciences
Hua Y,Han A,Yu T,Hou Y,Ding Y,Nie H
Fri May 06 00:00:00 EDT 2022
Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.
Electromagnetic biology and medicine
Liu J,Huang X,Zhou J,Li L,Xiao H,Qu M,Sun Z
Sun Jan 02 00:00:00 EST 2022
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
International journal of molecular sciences
Tiong TY,Weng PW,Wang CH,Setiawan SA,Yadav VK,Pikatan NW,Fong IH,Yeh CT,Hsu CH,Kuo KT
Thu Jun 30 00:00:00 EDT 2022
Ckip-1 Mediates P. gingivalis-Suppressed Cementoblast Mineralization.
Journal of dental research
Huang X,Ma L,Wang X,Wang H,Peng Y,Gao X,Huang H,Chen Y,Zhang Y,Cao Z
Sun May 01 00:00:00 EDT 2022
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Acta pharmacologica Sinica
Zhang B,Liu ZY,Wu R,Zhang CM,Cao K,Shan WG,Liu Z,Ji M,Tian ZL,Sethi G,Shi HL,Wang RH
Mon Aug 01 00:00:00 EDT 2022
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway.
World journal of gastrointestinal oncology
Teng YJ,Deng Z,Ouyang ZG,Zhou Q,Mei S,Fan XX,Wu YR,Long HP,Fang LY,Yin DL,Zhang BY,Guo YM,Zhu WH,Huang Z,Zheng P,Ning DM,Tian XF
Fri Apr 15 00:00:00 EDT 2022
Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.
Oxidative medicine and cellular longevity
Zhang Y,Xing CJ,Liu X,Li YH,Jia J,Feng JG,Yang CJ,Chen Y,Zhou J
Thu May 19 00:00:00 EDT 2022
PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.
International journal of molecular sciences
Sun M,Yan Q,Qiao Y,Zhao H,Wang Y,Shan C,Zhang S
Sun Sep 25 00:00:00 EDT 2022
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Proceedings of the National Academy of Sciences of the United States of America
Gao P,Liu Y,Wang H,Chai Y,Weng W,Zhang Y,Zhou L,Ge X,Guo X,Han J,Yang H
Tue Jul 19 00:00:00 EDT 2022
COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model.
American journal of physiology. Cell physiology
Tanaka K,Kuramoto K,Nakagawa T,Nomura Y,Ozawa K,Hosoi T
Thu Dec 01 00:00:00 EST 2022
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Cancer research
Xie B,Pu Y,Yang F,Chen W,Yue W,Ma J,Zhang N,Jiang Y,Wu J,Lin Y,Liang X,Wang C,Zou P,Li M
Mon Jul 18 00:00:00 EDT 2022
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
Clinical science (London, England : 1979)
Gao S,Yang Q,Liu Z,Kong W,Chen J,Li X,Peng Y,Bao M,Bian X,Zhang Y,Jiang Q,Li Z,Zhang Y,Yan F,Ye J
Wed Nov 30 00:00:00 EST 2022
Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.
Bioengineering & translational medicine
Hu F,Deng C,Zhou Y,Liu Y,Zhang T,Zhang P,Zhao Z,Miao H,Zheng W,Zhang W,Wang M,Ma X
Sun May 01 00:00:00 EDT 2022
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Molecular therapy. Nucleic acids
Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R
Tue Jun 14 00:00:00 EDT 2022
Characterization of Mitochondrial Alterations in Aicardi-Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes.
International journal of molecular sciences
Dragoni F,Garau J,Sproviero D,Orcesi S,Varesio C,De Siervi S,Gagliardi S,Cereda C,Pansarasa O
Mon Nov 21 00:00:00 EST 2022
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Journal of cellular and molecular medicine
Li M,Wang C,Yu Z,Lan Q,Xu S,Ye Z,Li R,Ying L,Zhang X,Zhou Z
Mon Aug 01 00:00:00 EDT 2022
Curcumin attenuates isoniazid-induced hepatotoxicity by upregulating the SIRT1/PGC-1α/NRF1 pathway.
Journal of applied toxicology : JAT
Li Y,Luo WW,Cheng X,Xiang HR,He B,Zhang QZ,Peng WX
Fri Jul 01 00:00:00 EDT 2022
Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.
Physiological reports
Ke Y,Proctor JL,Zhang C,Medina J,Miller CHT,Kim J,Grissom TE,Birukova AA,Fiskum GM,Birukov KG
Fri Jul 01 00:00:00 EDT 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
m6A modifications regulate intestinal immunity and rotavirus infection.
eLife
Wang A,Tao W,Tong J,Gao J,Wang J,Hou G,Qian C,Zhang G,Li R,Wang D,Ren X,Zhang K,Ding S,Flavell RA,Li H,Pan W,Zhu S
Mon Jan 31 00:00:00 EST 2022
Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1.
Neurochemical research
Wu X,Liu C,Wang J,Guan Y,Song L,Chen R,Gong M
Sat Oct 01 00:00:00 EDT 2022
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death
Liu S,Qiao X,Wu S,Gai Y,Su Y,Edwards H,Wang Y,Lin H,Taub JW,Wang G,Ge Y
Thu Dec 01 00:00:00 EST 2022
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Critical care (London, England)
Zhang L,Zhang Y,Qin X,Jiang X,Zhang J,Mao L,Jiang Z,Jiang Y,Liu G,Qiu J,Chen C,Qiu F,Zou Z
Thu Jun 09 00:00:00 EDT 2022
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Journal of virology
Gao C,Yu Y,Wen C,Li Z,Ding H,Qi X,Cardona CJ,Xing Z
Wed Jul 13 00:00:00 EDT 2022
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Journal of virology
Gao C,Yu Y,Wen C,Li Z,Ding H,Qi X,Cardona CJ,Xing Z
Wed Jul 13 00:00:00 EDT 2022
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Cell death & disease
Tang X,Liang Y,Sun G,He Q,Hou Z,Jiang X,Gao P,Qu H
Tue Oct 04 00:00:00 EDT 2022
C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens.
Communications biology
Ju S,Chen H,Wang S,Lin J,Ma Y,Aroian RV,Peng D,Sun M
Thu Jun 30 00:00:00 EDT 2022
Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.
Molecular medicine reports
Bai B,Li H,Han L,Mei Y,Hu C,Mei Q,Xu J,Liu X
Fri Apr 01 00:00:00 EDT 2022
Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer.
Science advances
Qin L,Wang L,Zhang J,Zhou H,Yang Z,Wang Y,Cai W,Wen F,Jiang X,Zhang T,Ye H,Long B,Qin J,Shi W,Guan X,Yu Z,Yang J,Wang Q,Jiao Z
Fri May 27 00:00:00 EDT 2022
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Molecular carcinogenesis
Fang J,Ma Y,Li Y,Li J,Zhang X,Han X,Ma S,Guan F
Tue Nov 01 00:00:00 EDT 2022
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Cell biology and toxicology
Xie C,Zhu J,Huang C,Yang X,Wang X,Meng Y,Geng S,Wu J,Shen H,Hu Z,Meng Z,Li X,Zhong C
Fri Apr 01 00:00:00 EDT 2022
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Journal of controlled release : official journal of the Controlled Release Society
Zheng Z,Guo Z,Zhong F,Wang B,Liu L,Ma W,Yu CY,Wei H
Fri Jul 01 00:00:00 EDT 2022
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Bioengineering & translational medicine
Mou Y,Wu GR,Wang Q,Pan T,Zhang L,Xu Y,Xiong W,Zhou Q,Wang Y
Sun May 01 00:00:00 EDT 2022
Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2.
Journal of applied microbiology
Mi J,Xie C,Zeng L,Zhu Z,Chen N,He Q,Xu X,Xie H,Zhou J,Li L,Liao J
Mon Aug 01 00:00:00 EDT 2022
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Pharmaceuticals (Basel, Switzerland)
Liu T,Gao H,Zhang Y,Wang S,Lu M,Dai X,Liu Y,Shi H,Xu T,Yin J,Gao S,Wang L,Zhang D
Mon Nov 21 00:00:00 EST 2022
Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis.
Frontiers in pharmacology
Liao C,Wang D,Qin S,Zhang Y,Chen J,Xu R,Xu F,Zhang P
Sat Jul 16 00:00:00 EDT 2022
TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.
Neuroscience
Huang R,Gao Y,Chen J,Duan Q,He P,Zhang J,Huang H,Zhang Q,Ma G,Zhang Y,Nie K,Wang L
Tue May 10 00:00:00 EDT 2022
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
Antiviral research
Liu J,Yao L,Huang S,Wang B,Li L,Li L,Gu W,Xiao S,Liu G
Wed Jun 01 00:00:00 EDT 2022
Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling pathway.
Molecular biology reports
Wang Y,Liu J,Yu B,Jin Y,Li J,Ma X,Yu J,Niu J,Liang X
Mon Aug 01 00:00:00 EDT 2022
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Scientific reports
Zhu Y,Jiang X,Ding Z,Ming J
Fri Jul 01 00:00:00 EDT 2022
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
British journal of pharmacology
Tingting W,Tianqi F,Xinyu W,Can Z,Xue S,Xuming D,Jianfeng W
Fri Jul 01 00:00:00 EDT 2022
PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.
Proceedings of the National Academy of Sciences of the United States of America
Ma S,Tang T,Wu X,Mansour AG,Lu T,Zhang J,Wang LS,Caligiuri MA,Yu J
Tue Jan 18 00:00:00 EST 2022
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
Journal of medicinal chemistry
Li Y,Zhang L,Yang R,Qiao Z,Wu M,Huang C,Tian C,Luo X,Yang W,Zhang Y,Li L,Yang S
Thu Feb 10 00:00:00 EST 2022
DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting EZH2.
BMC cancer
Chen R,Gan Q,Zhao S,Zhang D,Wang S,Yao L,Yuan M,Cheng J
Tue May 03 00:00:00 EDT 2022
Ultrasound-based radiomics for the evaluation of fetal rat lung maturity: A noninvasive assessment method (Ultrasound-based radiomics in fetal rat lung).
Prenatal diagnosis
Du Y,Jiao J,Cao A,Ji C,Li M,Ji C,Wu Y,Guo Y,Wang Y,Zhou J,Ren Y
Sat Oct 01 00:00:00 EDT 2022
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Cell death & disease
Su H,Liu B,Chen H,Zhang T,Huang T,Liu Y,Wang C,Ma Q,Wang Q,Lv Z,Wang R
Fri Jul 29 00:00:00 EDT 2022
Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation.
Journal of immunology research
Zhu L,Zhou KX,Ma MZ,Yao LL,Zhang YL,Li H,Du C,Yang XM
Fri Jul 01 00:00:00 EDT 2022
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Journal of cellular physiology
Jiang H,Niu Y,He Y,Li X,Xu Y,Liu X
Tue Mar 01 00:00:00 EST 2022
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou X,Wang W,Li Z,Chen L,Wen C,Ruan Q,Xu Z,Liu R,Xu J,Bai Y,Deng J
Sat Jan 01 00:00:00 EST 2022
LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway.
International journal of molecular sciences
Wang Y,Guo Y,Duan C,Li J,Ji S,Yan H,Liu Y,Zhang Y
Wed Oct 12 00:00:00 EDT 2022
Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling.
Frontiers in pharmacology
Ding Z,Zhao J,Wang X,Li W,Chen C,Yong C,Zhu Y,Tian F,Liu L,Yu M,Zhou E,Gu L,Yao C,Gao K
Wed Sep 07 00:00:00 EDT 2022
miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2.
Oxidative medicine and cellular longevity
Yan J,Wu LG,Zhang M,Fang T,Pan W,Zhao JL,Zhou Q
Tue Oct 11 00:00:00 EDT 2022
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
International immunopharmacology
He J,Liu L,Liu X,Chen H,Liu K,Huang N,Wang Y
Thu Dec 01 00:00:00 EST 2022
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Mediators of inflammation
Miao W,Chen M,Chen M,Cui C,Zhu Y,Luo X,Wu B
Mon Sep 12 00:00:00 EDT 2022
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Frontiers in genetics
Ziemann M,Wu W,Deng XL,Du XJ
Sat Jul 16 00:00:00 EDT 2022
Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.
Molecular oncology
Zhang H,Zhang N,Dai Z,Wang Z,Zhang X,Liang X,Zhang L,Feng S,Wu W,Ye W,Zhang J,Luo P,Liu Z,Cheng Q,Liu Z
Thu Dec 01 00:00:00 EST 2022
Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells.
Dose-response : a publication of International Hormesis Society
Yan J,Ma LP,Liu F,Sun B,Tian M,Lu X,Liu HX,Gao L,Liu QJ
Sun May 01 00:00:00 EDT 2022
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Molecular brain
Xu B,Yang R,Yang B,Li L,Chen J,Fu J,Qu X,Huo D,Tan C,Chen H,Peng Z,Wang X
Mon Jan 03 00:00:00 EST 2022
BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.
Dose-response : a publication of International Hormesis Society
He L,Zhou S,Li W,Wang Q,Qi Z,Zhou P,Wang Z,Chen J,Li Y,Lin Z
Fri May 06 00:00:00 EDT 2022
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Open medicine (Warsaw, Poland)
Qian W,Yang L,Ni Y,Yin F,Qin L,Yang Y
Wed Sep 07 00:00:00 EDT 2022
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
The Journal of biological chemistry
Ji R,Shi Q,Cao Y,Zhang J,Zhao C,Zhao H,Sayyed Y,Fu L,Li LY
Wed Jun 01 00:00:00 EDT 2022
Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer.
Frontiers in immunology
Zhang X,Zhang Y,Zhao L,Wang J,Li J,Wang X,Zhang M,Hu X
Tue Dec 27 00:00:00 EST 2022
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Mediators of inflammation
Tang R,Xiao G,Jian Y,Yuan Q,Jiang C,Wang W
Wed Jul 06 00:00:00 EDT 2022
Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.
Frontiers in cardiovascular medicine
Wang M,Alabi A,Gu HM,Gill G,Zhang Z,Jarad S,Xia XD,Shen Y,Wang GQ,Zhang DW
Tue Sep 13 00:00:00 EDT 2022
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Analytical cellular pathology (Amsterdam)
Gong J,Tang Z,Yu Z,Deng Z,Liu Y,Ren N,Wang L,He Z
Mon Apr 04 00:00:00 EDT 2022
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ding Q,Chen K,Liu X,Ding C,Zhao Y,Sun S,Zhang Y,Zhang J,Liu S,Liu W
Mon Aug 01 00:00:00 EDT 2022
Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway.
Frontiers in nutrition
Chen J,Huang Y,Bian X,He Y
Tue Mar 15 00:00:00 EDT 2022
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
Journal of cellular and molecular medicine
Wang J,Peng X,Yang D,Guo M,Xu X,Yin F,Wang Y,Huang J,Zhan L,Qi Z
Sat Jan 01 00:00:00 EST 2022
Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Cannabis and cannabinoid research
Kozakiewicz ML,Zhang J,Leone-Kabler S,Yamaleyeva LM,McDonald AG,Brost BC,Howlett AC
Wed Jun 01 00:00:00 EDT 2022
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway.
Experimental and therapeutic medicine
Hu W,Wu H,Li A,Zheng X,Zhang W,Tian Q,Zhang X
Thu Dec 01 00:00:00 EST 2022
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Biochemical and biophysical research communications
Shangguan Y,Chen Y,Ma Y,Zhao Y,He Y,Li W
Sat Jan 22 00:00:00 EST 2022
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.
Prostaglandins & other lipid mediators
Wang M,Su Y,Hou C,Ren K,Liu X,Zhao S,Wang Y,Liu X
Thu Dec 01 00:00:00 EST 2022
Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers.
Aging
Gao M,Zhang H,Gao Z,Sun Y,Xu G,Wei F,Wang J,Gao D
Sun Nov 27 00:00:00 EST 2022
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Wu GB,Du HB,Zhai JY,Sun S,Cui JL,Zhang Y,Zhao ZA,Wu JL,Johnson AK,Xue B,Zhao ZG,Zhang GS
Tue Mar 08 00:00:00 EST 2022
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Nucleic acids research
Wang Q,Xiao F,Su H,Liu H,Xu J,Tang H,Qin S,Fang Z,Lu Z,Wu J,Weng X,Zhou X
Fri Aug 12 00:00:00 EDT 2022
G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis.
Veterinary microbiology
Liu W,Yang Y,Zeng Z,Tian Y,Wu Q,Zhou M,Fu ZF,Zhao L
Tue Feb 01 00:00:00 EST 2022
Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.
Nucleic acids research
Hsu HT,Murata A,Dohno C,Nakatani K,Chang K
Fri May 20 00:00:00 EDT 2022
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Brain and behavior
Liu H,He S,Li C,Wang J,Zou Q,Liao Y,Chen R
Thu Dec 01 00:00:00 EST 2022
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Disease markers
Zhang J,Liu Z,Dong Y
Wed Jul 13 00:00:00 EDT 2022
Mechanosensitive Piezo1 channels mediate renal fibrosis.
JCI insight
Zhao X,Kong Y,Liang B,Xu J,Lin Y,Zhou N,Li J,Jiang B,Cheng J,Li C,Wang W
Fri Apr 08 00:00:00 EDT 2022
Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome.
Endocrine
Qiao G,Xing J,Luo X,Zhang C,Yi J
Thu Dec 01 00:00:00 EST 2022
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
Chemical biology & drug design
Liu L,Geng X,Zhang J,Li S,Gao J
Sat Oct 01 00:00:00 EDT 2022
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Clinical cancer research : an official journal of the American Association for Cancer Research
Hiatt JB,Sandborg H,Garrison SM,Arnold HU,Liao SY,Norton JP,Friesen TJ,Wu F,Sutherland KD,Rienhoff HY,Martins R,Houghton AM,Srivastava S,MacPherson D
Fri Oct 14 00:00:00 EDT 2022
Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation.
Frontiers in oncology
Xu X,Qi J,Yang J,Pan T,Han H,Yang M,Han Y
Sat Jul 16 00:00:00 EDT 2022
Themis is indispensable for IL-2 and IL-15 signaling in T cells.
Science signaling
Liu Y,Cong Y,Niu Y,Yuan Y,Tan F,Lai Q,Hu Y,Hou B,Li J,Lin C,Zheng H,Dong J,Tang J,Chen Q,Brzostek J,Zhang X,Chen XL,Wang HR,Gascoigne NRJ,Xu B,Lin SH,Fu G
Tue Feb 15 00:00:00 EST 2022
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Nature communications
Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW
Mon Nov 28 00:00:00 EST 2022
AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells.
Frontiers in cell and developmental biology
Lin CH,Kuo JC,Li D,Koenig AB,Pan A,Yan P,Bai XF,Lee RJ,Ghoshal K
Tue Jul 26 00:00:00 EDT 2022
Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.
Frontiers in medicine
Ye Z,Wang P,Feng G,Wang Q,Liu C,Lu J,Chen J,Liu P
Thu Feb 02 00:00:00 EST 2023
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
Molecular neurobiology
Zhou B,Zheng Y,Li X,Dong H,Yu J,Zou Y,Zhu M,Yu Y,Fang X,Zhou M,Zhang W,Yuan Y,Wang Z,Deng J,Hong D
Thu Dec 01 00:00:00 EST 2022
Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.
Pharmacological reports : PR
Fujii T,Kamishikiryo J,Morita T
Wed Jun 01 00:00:00 EDT 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
Neuropeptide Y promotes hepatic apolipoprotein A1 synthesis and secretion through neuropeptide Y Y5 receptor.
Peptides
Liu B,Chen F
Mon Aug 01 00:00:00 EDT 2022
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Molecular biology reports
Su Q,Wu Q,Chen K,Wang J,Sarwar A,Zhang Y
Tue Feb 01 00:00:00 EST 2022
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Wang J,Liu Z,Li W,Yu J,Zhang D
Sat Jan 01 00:00:00 EST 2022
TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats.
Vascular pharmacology
Zhao C,Hu L,He X,Li L,Yin M,Tettey AT,Wang Y,Shen J,Tang S,Wu C,Li Q,Wang Z,Li X
Mon Aug 01 00:00:00 EDT 2022
A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ42.
Journal of agricultural and food chemistry
Li S,Jin C,Gao P,Zhou W,Xiao R,Zhang Z,Liao W,Ding K
Wed Aug 17 00:00:00 EDT 2022
Wogonoside attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis through SOCS1/P53/SLC7A11 pathway.
Phytotherapy research : PTR
Liu G,Wei C,Yuan S,Zhang Z,Li J,Zhang L,Wang G,Fang L
Tue Nov 01 00:00:00 EDT 2022
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
Environmental microbiology
Yan Y,Tang J,Yuan Q,Liu H,Huang J,Hsiang T,Bao C,Zheng L
Tue Mar 01 00:00:00 EST 2022
Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.
Journal of Alzheimer's disease : JAD
Abdelhamid M,Zhou C,Ohno K,Kuhara T,Taslima F,Abdullah M,Jung CG,Michikawa M
Thu Mar 03 00:00:00 EST 2022
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Archives of oral biology
Zhang ZY,Sun YY,Wang HC,Fu WN,Sun CF
Sat Jan 01 00:00:00 EST 2022
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
ACS applied materials & interfaces
Li Y,Yang L,Hu F,Xu J,Ye J,Liu S,Wang L,Zhuo M,Ran B,Zhang H,Ye J,Xiao J
Wed Jun 08 00:00:00 EDT 2022
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Ecotoxicology and environmental safety
Liu C,Wu M,Qu J,Huang X,Zeng Q,Ha M
Wed Jun 15 00:00:00 EDT 2022
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Frontiers in immunology
Zhang M,Wu L,Deng Y,Peng F,Wang T,Zhao Y,Chen P,Liu J,Cai G,Wang L,Wu J,Chen X
Tue May 24 00:00:00 EDT 2022
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Frontiers in cardiovascular medicine
Song Q,Chen P,Wu SJ,Chen Y,Zhang Y
Mon May 02 00:00:00 EDT 2022
Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing.
Molecular genetics and metabolism
Venturoni LE,Chandler RJ,Liao J,Hoffmann V,Ramesh N,Gordo S,Chau N,Venditti CP
Wed Oct 26 00:00:00 EDT 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.
Evidence-based complementary and alternative medicine : eCAM
Su JC,Cheng C,Wang CY,Zhang Y,He YT,Guo ZW,Liu XY,Liu WM,Zhang YJ,Xu SW,Zhang XY,Liu ZB,Zhang XF
Thu Oct 06 00:00:00 EDT 2022
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.
International journal of molecular sciences
Fu J,Yu S,Zhao X,Zhang C,Shen L,Liu Y,Yu H
Fri Dec 16 00:00:00 EST 2022
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.
Frontiers in aging neuroscience
Zou K,Islam S,Sun Y,Gao Y,Nakamura T,Komano H,Tomita T,Michikawa M
Sat Jul 16 00:00:00 EDT 2022
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Frontiers in cell and developmental biology
Li C,Lin H,He H,Ma M,Jiang W,Zhou R
Tue Mar 08 00:00:00 EST 2022
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.
Neural regeneration research
Deng LD,Qi L,Suo Q,Wu SJ,Mamtilahun M,Shi RB,Liu Z,Sun JF,Tang YH,Zhang ZJ,Yang GY,Wang JX
Thu Sep 01 00:00:00 EDT 2022
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Journal of periodontology
Yu Y,Jiang L,Li J,Lei L,Li H
Fri Jul 01 00:00:00 EDT 2022
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Clinical and translational medicine
Liao W,Xu N,Zhang H,Liao W,Wang Y,Wang S,Zhang S,Jiang Y,Xie W,Zhang Y
Tue Feb 01 00:00:00 EST 2022
Morphological changes of macrophages and their potential contribution to tendon healing.
Colloids and surfaces. B, Biointerfaces
Yang QQ,Zhang L,Zhou YL,Tang JB
Sat Jan 01 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.
Food & function
Yang D,Yin R,Lei Q,Zhu J,Nan S,Ma N,Zhu H,Chen J,Han L,Ding M,Ding Y
Mon Jun 20 00:00:00 EDT 2022
Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.
Poultry science
Peng S,Fang C,He H,Song X,Zhao X,Zou Y,Li L,Jia R,Yin Z
Tue Mar 01 00:00:00 EST 2022
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
The Journal of cell biology
Li M,Feng F,Feng H,Hu P,Xue Y,Xu T,Song E
Mon Oct 03 00:00:00 EDT 2022
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor.
EBioMedicine
Zhang T,Guo Z,Huo X,Gong Y,Li C,Huang J,Wang Y,Feng H,Ma X,Jiang C,Yin Q,Xue L
Tue Mar 01 00:00:00 EST 2022
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Journal of Alzheimer's disease : JAD
Gao Z,Zhang R,Jiang L,Zhou H,Wang Q,Ma Y,Zhang D,Qin Y,Tian P,Zhang N,Shi Z,Xu S
Thu Mar 03 00:00:00 EST 2022
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Journal of oncology
Xu J,Li Y,Li Z,Shao W,Song J,Wei J
Tue Jan 25 00:00:00 EST 2022
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.
European journal of pharmacology
Zhang S,Pan C,Shang Q,Wang W,Hu T,Liu P,Chen S,Wang J,Fang Q
Tue Feb 15 00:00:00 EST 2022
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Acta pharmacologica Sinica
Yang WX,Liu Y,Zhang SM,Wang HF,Liu YF,Liu JL,Li XH,Zeng MR,Han YZ,Liu FY,Sun L,Xiao L
Tue Mar 01 00:00:00 EST 2022
Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.
Frontiers in cellular neuroscience
Xu B,Chen J,Fu J,Yang R,Yang B,Huo D,Tan C,Chen H,Wang X
Tue Mar 01 00:00:00 EST 2022
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
Food & function
Liu J,Jiang J,Qiu J,Wang L,Zhuo J,Wang B,Sun D,Yu S,Lou H
Tue Jan 04 00:00:00 EST 2022
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
Oncology letters
Zhang XW,Wu LY,Liu HR,Huang Y,Qi Q,Zhong R,Zhu L,Gao CF,Zhou L,Yu J,Wu HG
Thu Dec 01 00:00:00 EST 2022
Recovery Infectious Enterovirus 71 by Bac-to-Bac Expression System in vitro and in vivo.
Frontiers in microbiology
Lu B,Tang Q,Wang Q,Liu X,Peng H,Zhu B,Xie L,Li Z,Wang H,Zheng Z,Wang L,Li B
Fri Apr 01 00:00:00 EDT 2022
UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu H,Wang LL,Xu QH,Wang J,Zhang YJ,Luo J,Liao AH
Fri Apr 01 00:00:00 EDT 2022
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H2O2-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
Molecules (Basel, Switzerland)
Su J,Zhang X,Kan Q,Chu X
Sat Apr 30 00:00:00 EDT 2022
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Nature communications
Diao X,Ye F,Zhang M,Ren X,Tian X,Lu J,Sun X,Hou Z,Chen X,Li F,Zhuang J,Ding H,Peng C,Rastinejad F,Luo C,Wu D
Mon May 09 00:00:00 EDT 2022
Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice.
Food research international (Ottawa, Ont.)
Wang Y,Liu T,Xie Y,Li N,Liu Y,Wen J,Zhang M,Feng W,Huang J,Guo Y,Kabbas Junior T,Wang D,Granato D
Thu Dec 01 00:00:00 EST 2022
A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.
The FEBS journal
Ye Z,Ren C,Wang Q,Wang Y
Thu Sep 01 00:00:00 EDT 2022
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Frontiers in bioscience (Landmark edition)
Chen Y,Fang Y,Li L,Luo H,Cao T,Tu B
Thu Sep 29 00:00:00 EDT 2022
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Journal of medical virology
Han L,Zheng Y,Deng J,Nan ML,Xiao Y,Zhuang MW,Zhang J,Wang W,Gao C,Wang PH
Tue Nov 01 00:00:00 EDT 2022
Auxin and abscisic acid antagonistically regulate ascorbic acid production via the SlMAPK8-SlARF4-SlMYB11 module in tomato.
The Plant cell
Xu X,Zhang Q,Gao X,Wu G,Wu M,Yuan Y,Zheng X,Gong Z,Hu X,Gong M,Qi T,Li H,Luo Z,Li Z,Deng W
Thu Oct 27 00:00:00 EDT 2022
The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer.
Clinical Medicine Insights. Oncology
Liu T,Tang W,Chen Y,Liu Y,Xu D,Jiang Y,Zhou S,Qin X,Ren L,Chang W,Xu J
Fri Jul 29 00:00:00 EDT 2022
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Frontiers in pharmacology
Wang T,Lu Z,Qu XH,Xiong ZY,Wu YT,Luo Y,Zhang ZY,Han XJ,Xie CF
Sat Sep 24 00:00:00 EDT 2022
Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption.
Nutrients
Yu J,Liu T,Gao Z,Liu R,Wang Z,Chen Y,Cao J,Dong Y
Sat Jul 30 00:00:00 EDT 2022
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
International journal of radiation oncology, biology, physics
Chen G,Kong P,Yang M,Hu W,Prise KM,Yu KN,Cui S,Qin F,Meng G,Almahi WA,Nie L,Han W
Fri Apr 01 00:00:00 EDT 2022
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Physiological research
Liu X,Zhang K,Wang L,Geng B,Liu Z,Yi Q,Xia Y
Fri Dec 16 00:00:00 EST 2022
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Autophagy
Gong Y,Tang N,Liu P,Sun Y,Lu S,Liu W,Tan L,Song C,Qiu X,Liao Y,Yu S,Liu X,Lin SH,Ding C
Fri Jul 01 00:00:00 EDT 2022
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
International journal of biological sciences
Wang T,Lu Z,Han T,Wang Y,Gan M,Wang JB
Mon Jul 25 00:00:00 EDT 2022
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
The American journal of Chinese medicine
Zhou Y,Xiang S,Zheng H,Hou Y,Wang Y,Li CC,Wu Q,Shi J,Chen X
Fri Aug 12 00:00:00 EDT 2022
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
Journal of cellular and molecular medicine
He R,Yuan X,Lv X,Liu Q,Tao L,Meng J
Sat Jan 01 00:00:00 EST 2022
FGF15 Protects Septic Mice by Inhibiting Inflammation and Modulating Treg Responses.
Journal of inflammation research
Li X,Zhu Z,Xia Z,Xu B
Wed Mar 22 00:00:00 EDT 2023
Correlation Analysis of Umbilical Cord Blood Metabolic Phenotype and Inflammation in Patients with Gestational Diabetes Mellitus Complicated with Overweight and Obesity.
Evidence-based complementary and alternative medicine : eCAM
Chen Q,Li W,Deng Y,Li Y,Huang L,Zhao L,Li H
Sat Jul 16 00:00:00 EDT 2022
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Journal of cellular physiology
Dai Z,Wang K,Gao Y
Sat Jan 01 00:00:00 EST 2022
Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.
Advanced biology
Li Z,Li K,Sun Y,Jiang X,Liu J,Li J,Fang L,Li G,Guan Q,Xu C
Tue Nov 01 00:00:00 EDT 2022
USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses.
Frontiers in immunology
Zhang N,Wang F,Zhang G,Zhang Q,Liu Y,Wang Q,Elsharkawy MS,Zheng M,Wen J,Zhao G,Li Q
Tue Aug 30 00:00:00 EDT 2022
IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.
Stem cells (Dayton, Ohio)
Zhang Y,Zhang H,Xiao Z,Yuan G,Yang G
Tue Nov 29 00:00:00 EST 2022
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Phytotherapy research : PTR
Wu XY,Wang T,Hu HX,Zhang K,Zhao Y,Zhao BB,Lou HX,Wang XN,Shen T
Fri Apr 01 00:00:00 EDT 2022
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Cell proliferation
Yuan S,Wei C,Liu G,Zhang L,Li J,Li L,Cai S,Fang L
Sat Jan 01 00:00:00 EST 2022
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.
Cell
Fu A,Yao B,Dong T,Chen Y,Yao J,Liu Y,Li H,Bai H,Liu X,Zhang Y,Wang C,Guo Y,Li N,Cai S
Thu Apr 14 00:00:00 EDT 2022
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Drug metabolism and pharmacokinetics
Shinoda Y,Yamashiro T,Hosooka A,Yasujima T,Yuasa H
Fri Apr 01 00:00:00 EDT 2022
Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection.
Experimental and therapeutic medicine
Peng Y,Chen Y,Ma J,Zhou W,Wang Y,Wang Y,Zheng H,Shi W
Sat Jan 01 00:00:00 EST 2022
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Cell biology and toxicology
Wang H,Ai J,Shopit A,Niu M,Ahmed N,Tesfaldet T,Tang Z,Li X,Jamalat Y,Chu P,Peng J,Ma X,Qaed E,Han G,Zhang W,Wang J,Tang Z
Wed Jun 01 00:00:00 EDT 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Cell death & disease
Zhen Y,Yuan Z,Zhang J,Chen Y,Fu Y,Liu Y,Fu L,Zhang L,Zhou XL
Tue Apr 19 00:00:00 EDT 2022
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Zhou H,Zhang J,Yan Z,Qu M,Zhang G,Han J,Wang F,Sun K,Wang L,Yang X
Tue Mar 01 00:00:00 EST 2022
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Cells
Wu S,Edwards H,Wang D,Liu S,Qiao X,Carter J,Wang Y,Taub JW,Wang G,Ge Y
Sat Sep 03 00:00:00 EDT 2022
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Signal transduction and targeted therapy
Zheng Y,Deng J,Han L,Zhuang MW,Xu Y,Zhang J,Nan ML,Xiao Y,Zhan P,Liu X,Gao C,Wang PH
Mon Jan 24 00:00:00 EST 2022
Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth.
Journal of fish biology
Wu P,Chen L,Cheng J,Pan Y,Zhu X,Chu W,Zhang J
Fri Jul 01 00:00:00 EDT 2022
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles.
Biosafety and health
Wang S,Liu L,Wang C,Wang Z,Duan X,Chen G,Zhou H,Shao H
Tue Feb 01 00:00:00 EST 2022
Actin nucleator formins regulate the tension-buffering function of caveolin-1.
Journal of molecular cell biology
Shi X,Tang D,Xing Y,Zhao S,Fan C,Zhong J,Cui Y,Shi K,Jiu Y
Sat Jan 29 00:00:00 EST 2022
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Journal of virology
Pei J,Yuan Y,Tian D,Huang F,Zhang C,Wang C,Zhou M,Chen H,Fu Z,Zhao L
Wed Feb 23 00:00:00 EST 2022
Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment.
International journal of molecular sciences
Wang X,Li W,Jiang H,Ma C,Huang M,Wei X,Wang W,Jing L
Thu Jun 09 00:00:00 EDT 2022
Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.
Frontiers in pharmacology
Tang TL,Yang Y,Guo L,Xia S,Zhang B,Yan M
Fri Nov 18 00:00:00 EST 2022
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.
International journal of medical sciences
Yu M,Wu X,Wang J,He M,Han H,Hu S,Xu J,Yang M,Tan Q,Wang Y,Wang H,Xie W,Kong H
Thu May 19 00:00:00 EDT 2022
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.
Cell death & disease
Xiao J,Zhang L,Yi H,Zou L,Mo J,Xue F,Zheng J,Huang Y,Lu H,Wu H,Xue P,Zhang X,He L,Li Z,Pang S,Qiao G,Duan Q,Zhu F
Tue Sep 27 00:00:00 EDT 2022
The ubiquitin-26S proteasome system and autophagy relay proteome homeostasis regulation during silique development.
The Plant journal : for cell and molecular biology
Yu P,Hua Z
Thu Sep 01 00:00:00 EDT 2022
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Cellular oncology (Dordrecht)
Wang S,Wang T,Yang Q,Cheng S,Liu F,Yang G,Wang F,Wang R,Yang D,Zhou M,Duan C,Zhang Y,Liu H,Dai Z,Tian K,Liu S
Sat Oct 01 00:00:00 EDT 2022
Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.
International journal of molecular sciences
Ding X,Chen Y,Zhou L,Wu R,Jian T,Lyu H,Liu Y,Chen J
Sat Jul 02 00:00:00 EDT 2022
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
BMC pulmonary medicine
Li MY,Qin YQ,Tian YG,Li KC,Oliver BG,Liu XF,Zhao P,Li JS
Tue Nov 22 00:00:00 EST 2022
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Ma X,Zhang Y,Gou D,Ma J,Du J,Wang C,Li S,Cui H
Tue Jul 26 00:00:00 EDT 2022
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
International journal of molecular sciences
Xu L,Su B,Mo L,Zhao C,Zhao Z,Li H,Hu Z,Li J
Fri Apr 01 00:00:00 EDT 2022
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
Environmental pollution (Barking, Essex : 1987)
Qi M,Wang N,Xiao Y,Deng Y,Zha A,Tan B,Wang J,Yin Y,Liao P
Sat Jan 15 00:00:00 EST 2022
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway.
Frontiers in pharmacology
Dong M,Zeng J,Yang C,Qiu Y,Wang X
Sat Feb 26 00:00:00 EST 2022
The Effects of Intraoperative Hypothermia on Postoperative Cognitive Function in the Rat Hippocampus and Its Possible Mechanisms.
Brain sciences
Xu G,Li T,Huang Y
Wed Jan 12 00:00:00 EST 2022
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway.
Frontiers in pharmacology
Qi S,Zhang X,Fu Z,Pi A,Shi F,Fan Y,Zhang J,Xiao T,Shang D,Lin M,Gao N,Chang J,Gao Y
Tue Aug 09 00:00:00 EDT 2022
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Oxidative medicine and cellular longevity
Xia B,Zhu R,Zhang H,Chen B,Liu Y,Dai X,Ye Z,Zhao D,Mo F,Gao S,Wang XD,Bromme D,Wang L,Wang X,Zhang D
Thu Mar 17 00:00:00 EDT 2022
Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.
Advances in redox research
Boos JR,Jandrain HN,Hagiuda E,Taguchi AT,Hasegawa K,Fedun BL,Taylor SJ,Elad SM,Faber SE,Kumasaka T,Iwasaki T,Geldenhuys WJ
Thu Dec 01 00:00:00 EST 2022
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Behavioural brain research
Yang SQ,Tang YY,Zeng D,Tian Q,Wei HJ,Wang CY,Zhang P,Chen YJ,Zou W,Tang XQ
Mon Jan 24 00:00:00 EST 2022
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Bioengineered
Xiang J,Zhang C,Di T,Chen L,Zhao W,Wei L,Zhou S,Wu X,Wang G,Zhang Y
Tue Feb 01 00:00:00 EST 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
International journal of endocrinology
Hu H,Luo Z,Liu X,Huang L,Lu X,Ding R,Duan C,He Y
Thu Dec 22 00:00:00 EST 2022
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Journal of ethnopharmacology
Ren X,Xing Y,He L,Xiu Z,Yang L,Han A,Jia Q,Dong Y
Tue May 10 00:00:00 EDT 2022
Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.
NanoImpact
Pei Z,Ning J,Zhang N,Zhang X,Zhang H,Zhang R
Fri Apr 01 00:00:00 EDT 2022
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Chinese medicine
Huang W,Wen F,Gu P,Liu J,Xia Y,Li Y,Zhou J,Song S,Ruan S,Gu S,Chen X,Shu P
Tue Aug 09 00:00:00 EDT 2022
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
International immunopharmacology
Liang R,Yuan Y,Bai Y,Liu X,Chen J,Jiang D,Meng D,Chen G,Li B,Zhou L,Guo W
Thu Sep 01 00:00:00 EDT 2022
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Respiratory research
Dai Z,Liu X,Zeng H,Chen Y
Sat Dec 17 00:00:00 EST 2022
Spinal 5-HT2A receptor is involved in electroacupuncture inhibition of chronic pain.
Molecular pain
Yuan XC,Wang YY,Tian LX,Yan XJ,Guo YX,Zhao YL,Baba SS,Jia H,Wang HS,Li M,Huo FQ
Tue Apr 12 00:00:00 EDT 2022
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Nature communications
Song K,Yang X,An G,Xia X,Zhao J,Xu X,Wan C,Liu T,Zheng Y,Ren S,Wang M,Chang G,Cronin SJF,Penninger JM,Jing T,Ou X,Rao S,Liu Z,Zhao XY
Mon Nov 28 00:00:00 EST 2022
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Free radical biology & medicine
Peng X,Su S,Zeng J,Xie K,Yang X,Xian G,Xiao Z,Zhu P,Zheng S,Xu D,Zeng Q
Mon Aug 01 00:00:00 EDT 2022
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Disease markers
Wen Y,Li Y,Yang B,Guo X,Lin L,Liang J,Zhang K,Li X,Jiang Z,Wang Y,Li Y,Wu X,Fan X,Li F,Yuan W
Mon Nov 28 00:00:00 EST 2022
miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2.
American journal of cancer research
Jiang P,Mao L,Lei X,Luo C,Zhang Y,Zhong X,Yin Z,Xu X,Li D,Zheng Q
Tue Aug 16 00:00:00 EDT 2022
Lactobacillus plantarum RS-09 Induces M1-Type Macrophage Immunity Against Salmonella Typhimurium Challenge via the TLR2/NF-κB Signalling Pathway.
Frontiers in pharmacology
Zhao C,Chen H,Liang H,Zhao X,Tang W,Wei M,Li Y,Zhang J,Yu X,Chen G,Zhu H,Jiang L,Zhang X
Mon Jun 20 00:00:00 EDT 2022
CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.
Biochemical and biophysical research communications
Hao S,Yang C,Song P,Shi H,Zou Y,Chen M,Wu X,Yin Y,Yu Z,Zhu W,Li M
Sat Sep 03 00:00:00 EDT 2022
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Food & function
Zhong X,Wu Q,Wang Z,Zhang M,Zheng S,Shi F,Chen Y,Che Y,Yuan S,Xing K
Mon Jul 18 00:00:00 EDT 2022
High expression of PTGES3 is an independent predictive poor prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.
International immunopharmacology
Gao P,Zou K,Xiao L,Zhou H,Xu X,Zeng Z,Zhang W
Thu Sep 01 00:00:00 EDT 2022
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Food & function
Lu H,Yin H,Qu L,Ma X,Fu R,Fan D
Mon Apr 04 00:00:00 EDT 2022
Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability.
Molecular neurobiology
Yang B,Xu B,Yang R,Fu J,Li L,Huo D,Chen J,Yang X,Tan C,Chen H,Wang X
Tue Mar 01 00:00:00 EST 2022
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Experimental eye research
Wu J,Wang J,Wang L,Huang Y
Sat Jan 01 00:00:00 EST 2022
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Experimental eye research
Wu J,Wang J,Wang L,Huang Y
Sat Jan 01 00:00:00 EST 2022
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
ACS nano
Li Y,Cen Y,Fang Y,Tang S,Li S,Ren Y,Zhang H,Lu W,Xu J
Tue Aug 23 00:00:00 EDT 2022
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Cell chemical biology
Wang P,Zhang T,Wang X,Xiao H,Li H,Zhou LL,Yang T,Wei B,Zhu Z,Zhou L,Yang S,Lu X,Zhang Y,Huang Y,Gan J,Yang CG
Thu Sep 15 00:00:00 EDT 2022
Melatonin Alleviates Oxidative Stress Induced by H2O2 in Porcine Trophectoderm Cells.
Antioxidants (Basel, Switzerland)
Fu Y,Chen Y,Jin Z,Gao H,Song G,Wang Q,Xu K
Wed May 25 00:00:00 EDT 2022
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Food & function
Yan S,Chen J,Zhu L,Guo T,Qin D,Hu Z,Han S,Wang J,Matias FB,Wen L,Luo F,Lin Q
Wed Apr 20 00:00:00 EDT 2022
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Frontiers in medicine
Pei Z,Wu M,Yu H,Long G,Gui Z,Li X,Chen H,Jia Z,Xia W
Tue May 03 00:00:00 EDT 2022
miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway.
Diabetes, metabolic syndrome and obesity : targets and therapy
Jiang Y,Wei L,Zhang H,Chen Y,Gao P,Zhang J,Zhou X,Zhu S,Du Y,Fang C,Li J,Feng L,He M,Wang S,Yu J
Tue Nov 08 00:00:00 EST 2022
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Cell chemical biology
Wolff DW,Deng Z,Bianchi-Smiraglia A,Foley CE,Han Z,Wang X,Shen S,Rosenberg MM,Moparthy S,Yun DH,Chen J,Baker BK,Roll MV,Magiera AJ,Li J,Hurley E,Feltri ML,Cox AO,Lee J,Furdui CM,Liu L,Bshara W,LaConte LEW,Kandel ES,Pasquale EB,Qu J,Hedstrom L,Nikiforov MA
Thu Jun 16 00:00:00 EDT 2022
High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.
Scientific reports
Liu Q,Bai Y,Shi X,Guo D,Wang Y,Wang Y,Guo WZ,Zhang S
Wed Oct 19 00:00:00 EDT 2022
Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair.
Frontiers in bioengineering and biotechnology
Zhu H,Xu J,Zhao M,Luo H,Lin M,Luo Y,Li Y,He H,Wu J
Tue Sep 20 00:00:00 EDT 2022
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress.
Frontiers in immunology
Lei L,Ji M,Yang J,Chen S,Gu H,Yang JJ
Fri Aug 26 00:00:00 EDT 2022
Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.
Clinical, cosmetic and investigational dermatology
Li L,Lu H,Zhang Y,Li Q,Shi S,Liu Y
Fri Dec 02 00:00:00 EST 2022
Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice.
Nutrients
Abdelhamid M,Zhou C,Jung CG,Michikawa M
Sun Jun 19 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Mitochondrial Transplantation Promotes Remyelination and Long-Term Locomotion Recovery following Cerebral Ischemia.
Mediators of inflammation
Chen T,Zhu Y,Jia J,Meng H,Xu C,Xian P,Li Z,Tang Z,Wu Y,Liu Y
Wed Sep 28 00:00:00 EDT 2022
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Aging
Wang S,Duan J,Liao J,Wang Y,Xiao X,Li L,Liu Y,Gu H,Yang P,Fu D,Du J,Li X,Shao M
Tue Aug 30 00:00:00 EDT 2022
Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice.
Current issues in molecular biology
Li W,Wang Z,Cao J,Dong Y,Chen Y
Tue Jan 25 00:00:00 EST 2022
Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.
Theranostics
He F,Li WN,Li XX,Yue KY,Duan JL,Ruan B,Liu JJ,Song P,Yue ZS,Tao KS,Wang L
Thu Apr 21 00:00:00 EDT 2022
DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation.
Neurobiology of stress
Chen X,He JL,Liu XT,Zhao N,Geng F,Zhu MM,Liu GP,Ren QG
Thu Sep 01 00:00:00 EDT 2022
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
Frontiers in pharmacology
He W,Xi Q,Cui H,Zhang P,Huang R,Wang T,Wang D
Tue Nov 22 00:00:00 EST 2022
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.
Biomolecules
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Wang LC
Fri Jan 21 00:00:00 EST 2022
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Frontiers in oncology
Zu F,Chen H,Liu Q,Zang H,Li Z,Tan X
Wed Feb 16 00:00:00 EST 2022
Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
Frontiers in cardiovascular medicine
Osuru HP,Lavallee M,Thiele RH
Sat Aug 06 00:00:00 EDT 2022
Effect of Qingyangshen glycosides on social defeat mice model.
Journal of ethnopharmacology
Liu D,Wang J,Chang L,Zhu Q,Jiang N,Azhar M,Zeng G
Fri Jul 15 00:00:00 EDT 2022
Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication.
Frontiers in microbiology
Yang X,Chen J,Lu Z,Huang S,Zhang S,Cai J,Zhou Y,Cao G,Yu J,Qin Z,Zhao W,Zhang B,Zhu L
Wed Oct 19 00:00:00 EDT 2022
Integrative proteomics and m6A microarray analyses of the signatures induced by METTL3 reveals prognostically significant in gastric cancer by affecting cellular metabolism.
Frontiers in oncology
Peng G,Chen S,Zheng N,Tang Y,Su X,Wang J,Dong R,Wu D,Hu M,Zhao Y,Liu M,Wu H
Tue Dec 06 00:00:00 EST 2022
ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells.
DNA and cell biology
Jiang F,Shen Q,Zhang F,Fu J,Hu L,Wang J,Zhou H,Chen J,Wang Y
Wed Jun 01 00:00:00 EDT 2022
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
International journal of biological sciences
Miao J,Zhao C,Tang K,Xiong X,Wu F,Xue W,Duan B,Zhang H,Jing X,Li W,Sun Y,Hou N,Huang C
Thu Apr 14 00:00:00 EDT 2022
COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.
Current issues in molecular biology
Zhang H,Yan T,Zhong A,Guo L,Lu R
Thu Sep 01 00:00:00 EDT 2022
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Molecular pharmaceutics
Yang X,Shang P,Ji J,Malichewe C,Yao Z,Liao J,Du D,Sun C,Wang L,Tang YJ,Guo X
Mon Jan 03 00:00:00 EST 2022
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Frontiers in cellular neuroscience
Rong ZJ,Cai HH,Wang H,Liu GH,Zhang ZW,Chen M,Huang YL
Tue May 24 00:00:00 EDT 2022
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Food & function
Huang P,Luo FJ,Ma YC,Wang SX,Huang J,Qin DD,Xue FF,Liu BY,Wu Q,Wang XL,Liu GQ
Tue Aug 30 00:00:00 EDT 2022
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
EMBO reports
Yuan Y,Miao Y,Ren T,Huang F,Qian L,Chen X,Zuo Y,Zhang HG,He J,Qiao C,Du Q,Wu Q,Zhang W,Zhu C,Xu Y,Wu D,Shi W,Jiang J,Xu G,Zheng H
Wed Jan 05 00:00:00 EST 2022
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
International immunopharmacology
Yang L,Chen H,Hu Q,Liu L,Yuan Y,Zhang C,Tang J,Shen X
Sat Oct 01 00:00:00 EDT 2022
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
Cell proliferation
Chen L,Liu Z,Tang H,Zhou Z,Chen J,Ma Z,Deng M,Li X,Wu Y,Zheng L,Zhou L,Zheng X,Liu Z
Thu Dec 01 00:00:00 EST 2022
Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.
Nucleic acids research
Wu S,Ge Y,Lin K,Liu Q,Zhou H,Hu Q,Zhao Y,He W,Ju Z
Fri Apr 22 00:00:00 EDT 2022
Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation.
Oxidative medicine and cellular longevity
Cao M,Ma R,Li H,Cui J,Zhang C,Zhao J
Mon Apr 04 00:00:00 EDT 2022
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Journal of clinical laboratory analysis
Yao J,Wu J,Jia S,Shao J,Zhang X,Xu Z,Zhang H,Li H,Yao X
Thu Dec 01 00:00:00 EST 2022
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Oncogene
Liu Y,Ouyang L,Mao C,Chen Y,Li T,Liu N,Wang Z,Lai W,Zhou Y,Cao Y,Liu S,Liang Y,Wang M,Liu S,Chen L,Shi Y,Xiao D,Tao Y
Fri Jul 01 00:00:00 EDT 2022
The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Han D,Wang L,Long L,Su P,Luo D,Zhang H,Li Z,Chen B,Zhao W,Zhang N,Wang X,Liang Y,Li Y,Hu G,Yang Q
Thu Sep 01 00:00:00 EDT 2022
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Molecular and cellular endocrinology
Du X,Osoro EK,Chen Q,Yan X,Gao D,Wu L,Ren J,Feng L,Wu N,Lu K,Yang X,Zhong B,Han Y,Zhang F,Li D,Lan X,Lu S
Tue Apr 05 00:00:00 EDT 2022
Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.
Frontiers in oncology
Yan Z,Da Q,Li Z,Lin Q,Yi J,Su Y,Yu G,Ren Q,Liu X,Lin Z,Qu J,Yin W,Liu J
Tue Mar 01 00:00:00 EST 2022
Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.
Journal of neurochemistry
Meng D,Yang M,Hu L,Liu T,Zhang H,Sun X,Wang X,Chen Y,Jin Y,Liu R
Thu Dec 01 00:00:00 EST 2022
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
Cancer letters
He R,Shi J,Xu D,Yang J,Shen Y,Jiang YS,Tao L,Yang M,Fu X,Yang JY,Liu D,Huo Y,Shen X,Lu P,Niu N,Sun YW,Xue J,Liu W
Sun Jul 10 00:00:00 EDT 2022
Oridonin Delays Aging Through the AKT Signaling Pathway.
Frontiers in pharmacology
An Y,Zhu J,Wang X,Sun X,Luo C,Zhang Y,Ye Y,Li X,Abulizi A,Huang Z,Zhang H,Yang B,Xie Z
Sat Jul 16 00:00:00 EDT 2022
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
BMC cancer
Song J,Ruze R,Chen Y,Xu R,Yin X,Wang C,Xu Q,Zhao Y
Tue Aug 16 00:00:00 EDT 2022
Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
Cancer immunology research
Lou Y,Song M,Han M,Zhong J,Tian X,Ren Y,Song Y,Duan L,Zhao P,Song X,Zhang W,Chen YH,Wang H
Tue Mar 01 00:00:00 EST 2022
SORTING NEXIN2 proteins mediate stomatal movement and the response to drought stress by modulating trafficking and protein levels of the ABA exporter ABCG25.
The Plant journal : for cell and molecular biology
Liang C,Li C,Wu J,Zhao M,Chen D,Liu C,Chu J,Zhang W,Hwang I,Wang M
Wed Jun 01 00:00:00 EDT 2022
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Frontiers in oncology
Wen X,Chen S,Chen X,Qiu H,Wang W,Zhang N,Liu W,Wang T,Ding X,Zhang L
Wed Oct 19 00:00:00 EDT 2022
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
Gut microbes
Ghazisaeedi F,Meens J,Hansche B,Maurischat S,Schwerk P,Goethe R,Wieler LH,Fulde M,Tedin K
Fri Aug 05 00:00:00 EDT 2022
LMOD1, an oncogene associated with Lauren classification, regulates the metastasis of gastric cancer cells through the FAK-AKT/mTOR pathway.
BMC cancer
Tan Y,Chen Q,Pan S,An W,Xu H,Xing Y,Zhang J
Sat Apr 30 00:00:00 EDT 2022
The function and mechanism of dopamine in the activation of CD4+ T cell.
Immunopharmacology and immunotoxicology
Shao Y,Dong Y,Wang W,Chen Z,Hao C,Yang Y,Zhang J
Wed Jun 01 00:00:00 EDT 2022
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Nutrition and cancer
Cui L,Li Z,Xu F,Tian Y,Chen T,Li J,Guo Y,Lyu Q
Tue Apr 26 00:00:00 EDT 2022
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Oxidative medicine and cellular longevity
Gao S,Zhou L,Lu J,Fang Y,Wu H,Xu W,Pan Y,Wang J,Wang X,Zhang J,Shao A
Tue Apr 05 00:00:00 EDT 2022
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Frontiers in molecular biosciences
Lyu L,Cai Y,Zhang G,Jing Z,Liang J,Zhang R,Dang X,Zhang C
Sat Oct 29 00:00:00 EDT 2022
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
Gut
Sun X,He X,Zhang Y,Hosaka K,Andersson P,Wu J,Wu J,Jing X,Du Q,Hui X,Ding B,Guo Z,Hong A,Liu X,Wang Y,Ji Q,Beyaert R,Yang Y,Li Q,Cao Y
Sat Jan 01 00:00:00 EST 2022
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
iScience
Ding DX,Wang Y,Yan W,Fu WN
Fri Mar 18 00:00:00 EDT 2022
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
Cell communication and signaling : CCS
Duan M,Chen H,Yin L,Zhu X,Novák P,Lv Y,Zhao G,Yin K
Sat May 07 00:00:00 EDT 2022
Down-regulation of NR2B receptors contributes to the analgesic and antianxiety effects of enriched environment mediated by endocannabinoid system in the inflammatory pain mice.
Behavioural brain research
Jiang S,Zheng C,Wen G,Bu B,Zhao S,Xu X
Fri Oct 28 00:00:00 EDT 2022
The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Nature immunology
Concepcion AR,Wagner LE,Zhu J,Tao AY,Yang J,Khodadadi-Jamayran A,Wang YH,Liu M,Rose RE,Jones DR,Coetzee WA,Yule DI,Feske S
Tue Feb 01 00:00:00 EST 2022
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Stem cell research & therapy
Tan J,Xu T,Gou Y,Wang H,Liang Z,Cao Y,Wang H,Yu Y,Jiao N,Zhang Z
Fri Jul 15 00:00:00 EDT 2022
LPS Activated Macrophages Induced Hepatocyte Pyroptosis via P2X7R Activation of NLRP3 in Mice.
Iranian journal of immunology : IJI
Luo L,Fang Y,Yuan Q,Liao J,Zhang Z
Tue Mar 01 00:00:00 EST 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos.
Cell proliferation
Zhang S,Gong X,Zhou Y,Ma Q,Cai Q,Yang G,Guo X,Chen Y,Xu M,Zhu Y,Zeng Y,Zeng F
Wed Jun 01 00:00:00 EDT 2022
Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.
Bioorganic chemistry
Wei B,Zhang J,Li NN,Yang LH,Xu XL,Shi YY,Liu SH,Chen YJ
Fri Jul 01 00:00:00 EDT 2022
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
Journal of cellular and molecular medicine
Nishikubo K,Ohgaki R,Okanishi H,Okuda S,Xu M,Endou H,Kanai Y
Sat Oct 01 00:00:00 EDT 2022
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Cell death & disease
Zhu X,Chen Z,Wang L,Ou Q,Feng Z,Xiao H,Shen Q,Li Y,Jin C,Xu JY,Gao F,Wang J,Zhang J,Zhang J,Xu Z,Xu GT,Lu L,Tian H
Mon Sep 12 00:00:00 EDT 2022
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling.
Glycoconjugate journal
Liao W,Hu X,Du Z,Wang P,Ding K
Thu Dec 01 00:00:00 EST 2022
NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry.
Science China. Life sciences
Li G,Su B,Fu P,Bai Y,Ding G,Li D,Wang J,Yang G,Chu B
Tue Feb 01 00:00:00 EST 2022
Cortisol Stimulates Local Progesterone Withdrawal Through Induction of AKR1C1 in Human Amnion Fibroblasts at Parturition.
Endocrinology
Lu JW,Lei WJ,Ling LJ,Wang LY,Lin YK,Zhang F,Li MD,Pan F,Wang WS,Sun K
Tue Oct 11 00:00:00 EDT 2022
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Disease markers
Liu X,Wang M,Kan Q,Lin Y,Jiang Z
Wed Aug 23 00:00:00 EDT 2023
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Redox biology
Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y
Fri Jul 01 00:00:00 EDT 2022
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
Cellular signalling
Hou W,Lu L,Li X,Sun M,Zhu M,Miao C
Fri Apr 01 00:00:00 EDT 2022
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
Oxidative medicine and cellular longevity
Liang G,Zeng M,Gao M,Xing W,Jin X,Wang Q,Deng L,Ou H,He Z
Tue Mar 08 00:00:00 EST 2022
Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation.
Oxidative medicine and cellular longevity
Li Y,Pan D,Wang X,Huo Z,Wu X,Li J,Cao J,Xu H,Du L,Xu B
Fri Apr 29 00:00:00 EDT 2022
iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Liu H,Wang H,Chen S,Liu S,Tian X,Dong Z,Xu L
Sun May 01 00:00:00 EDT 2022
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Journal of cardiovascular translational research
Cheng L,Wang H,Maboh R,Mao G,Wu X,Chen H
Sat Oct 01 00:00:00 EDT 2022
Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.
ACS nano
Wu F,Du Y,Yang J,Shao B,Mi Z,Yao Y,Cui Y,He F,Zhang Y,Yang P
Tue Mar 22 00:00:00 EDT 2022
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Cell communication and signaling : CCS
Yao R,Zhang M,Zhou J,Liu L,Zhang Y,Gao J,Xu K
Thu May 26 00:00:00 EDT 2022
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H2S in Diabetes.
Aging and disease
Xi Y,Wen X,Zhang Y,Jiao L,Bai S,Shi S,Chang G,Wu R,Sun F,Hao J,Li H
Wed Jun 01 00:00:00 EDT 2022
Polystyrene Microplastics Postpone APAP-Induced Liver Injury through Impeding Macrophage Polarization.
Toxics
Liu J,Zhang L,Xu F,Meng S,Li H,Song Y
Fri Dec 16 00:00:00 EST 2022
Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts.
Animals : an open access journal from MDPI
Liu Y,Ding H,Yang Y,Liu Y,Cao X,Feng T
Sat Oct 08 00:00:00 EDT 2022
Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.
Frontiers in immunology
Zheng Y,Fan L,Xia S,Yang Q,Zhang Z,Chen H,Zeng H,Fu X,Peng Y,Xu C,Yu K,Liu F,Cao S
Tue Oct 04 00:00:00 EDT 2022
Exogenous Linoleic Acid Intervention Alters Hepatic Glucose Metabolism in an Avian Embryo Model.
Frontiers in physiology
Zhang X,Wu Q,Zheng W,Liu C,Huang L,Zuo X,Xiao W,Han X,Ye H,Wang W,Zhu Y,Yang L
Fri Mar 11 00:00:00 EST 2022
Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.
Immunology
Zhu Y,Zhang X,Xie S,Bao W,Chen J,Wu Q,Lai X,Liu L,Xiong S,Peng Y
Thu Dec 01 00:00:00 EST 2022
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
Journal of ethnopharmacology
Chen T,Su S,Yang Z,Zhang D,Li Z,Lu D
Fri Oct 28 00:00:00 EDT 2022
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Carbohydrate polymers
Li Z,Meng Z,Zhao Z
Tue Feb 01 00:00:00 EST 2022
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Toxicology letters
Liu K,Zhao X,Guo M,Zhu J,Li D,Ding J,Han X,Wu J
Fri Apr 01 00:00:00 EDT 2022
Schizosaccharomyces pombe Fzo1 is subjected to the ubiquitin-proteasome-mediated degradation during the stationary phase.
International microbiology : the official journal of the Spanish Society for Microbiology
Ahmad F,Zhang Y,Yin H,Luo Y,Huang Y
Sun May 01 00:00:00 EDT 2022
USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer.
Acta biochimica et biophysica Sinica
Liu Y,Xu J,Wang Y,Gan M,Hu Q,Wang J,Han T
Fri Nov 25 00:00:00 EST 2022
Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats.
Frontiers in bioengineering and biotechnology
Zhang Y,Wang Z,Zong C,Gu X,Fan S,Xu L,Cai B,Lu S
Thu Feb 02 00:00:00 EST 2023
Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells.
Cellular & molecular biology letters
Zhao JZ,Li QY,Lin JJ,Yang LY,Du MY,Wang Y,Liu KX,Jiang ZA,Li HH,Wang SF,Sun B,Mu SQ,Li B,Liu K,Gong M,Sun SG
Wed Jun 15 00:00:00 EDT 2022
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
Journal of nanobiotechnology
Bae KH,Lai F,Mong J,Niibori-Nambu A,Chan KH,Her Z,Osato M,Tan MH,Chen Q,Kurisawa M
Wed Nov 16 00:00:00 EST 2022
Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.
International immunopharmacology
Liu Y,Chen S,Yu L,Deng Y,Li D,Yu X,Chen D,Lu Y,Liu S,Chen R
Fri Jul 01 00:00:00 EDT 2022
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang W,Rong G,Gu J,Fan C,Guo T,Jiang T,Deng W,Xie J,Su Z,Yu Q,Mai J,Zheng R,Chen X,Tang X,Zhang J
Tue Mar 01 00:00:00 EST 2022
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
ACS chemical biology
Lyu Z,Sycks MM,Espinoza MF,Nguyen KK,Montoya MR,Galapate CM,Mei L,Genereux JC
Fri Jul 15 00:00:00 EDT 2022
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Transplant immunology
Xu Z,Sun X,Ding B,Zi M,Ma Y
Sat Oct 01 00:00:00 EDT 2022
Regulation of chromatin accessibility by hypoxia and HIF.
The Biochemical journal
Batie M,Frost J,Shakir D,Rocha S
Thu Mar 31 00:00:00 EDT 2022
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
iScience
Li F,Rong Z,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Oct 21 00:00:00 EDT 2022
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Toxicology letters
Gu W,Wang L,Deng G,Gu X,Tang Z,Li S,Jin W,Yang J,Guo X,Li Q
Tue Mar 01 00:00:00 EST 2022
miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2.
Experimental and therapeutic medicine
Zhang H,Wang Y,Wu K,Liu R,Wang H,Yao Y,Kvietys P,Rui T
Thu Dec 01 00:00:00 EST 2022
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
EBioMedicine
Xu S,Yang X,Chen Q,Liu Z,Chen Y,Yao X,Xiao A,Tian J,Xie L,Zhou M,Hu Z,Zhu F,Xu X,Hou F,Nie J
Thu Dec 01 00:00:00 EST 2022
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Journal of agricultural and food chemistry
Hu S,Luo L,Bian X,Liu RH,Zhao S,Chen Y,Sun K,Jiang J,Liu Z,Zeng L
Wed May 11 00:00:00 EDT 2022
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
The Science of the total environment
Zhou J,Zeng L,Zhang Y,Wang M,Li Y,Jia Y,Wu L,Su P
Tue Nov 15 00:00:00 EST 2022
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Hu W,Wang Z,Zhang H,Mahaman YAR,Huang F,Meng D,Zhou Y,Wang S,Jiang N,Xiong J,Westermarck J,Lu Y,Wang J,Wang X,Shentu Y,Liu R
Tue Mar 01 00:00:00 EST 2022
Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9.
Frontiers in oncology
Han P,Cao P,Yue J,Kong K,Hu S,Deng Y,Li L,Li F,Zhao B
Sat Jul 16 00:00:00 EDT 2022
LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.
Stem cell research & therapy
Gao H,Dong H,Zheng J,Jiang X,Gong M,Hu L,He J,Wang Y
Sat Jan 29 00:00:00 EST 2022
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
International journal of chronic obstructive pulmonary disease
Liu J,Zhang Z,Yang Y,Di T,Wu Y,Bian T
Fri Apr 08 00:00:00 EDT 2022
Methionine deprivation inhibits glioma growth through downregulation of CTSL.
American journal of cancer research
Qian F,Xu H,Zhang Y,Li L,Yu R
Wed Dec 21 00:00:00 EST 2022
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Brain research
Yu D,Zhao XY,Meng QP,Teng D,Deng K,Lin N
Thu Dec 01 00:00:00 EST 2022
Pathogenic variants in TSC2 might cause premature ovarian insufficiency through activated mTOR induced hyperactivation of primordial follicles.
Fertility and sterility
Xu B,Li Z,Li S,Ke H,Zhang Q,Qin Y,Guo T
Thu Dec 01 00:00:00 EST 2022
Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Qian LL,Ji JJ,Jiang Y,Guo JQ,Wu Y,Yang Z,Ma GS,Yao YY
Sun May 01 00:00:00 EDT 2022
Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells.
Journal of gastrointestinal oncology
Geng D,Wu H
Wed Jun 01 00:00:00 EDT 2022
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Journal of ethnopharmacology
He M,Li L,Wei X,Geng D,Jiang H,Xiangxiang G,Zhang Y,Du H
Mon Jan 10 00:00:00 EST 2022
A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ.
Journal of ginseng research
Chen L,Li R,Chen F,Zhang H,Zhu Z,Xu S,Cheng Y,Zhao Y
Thu Sep 01 00:00:00 EDT 2022
Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.
Oxidative medicine and cellular longevity
Hou W,Liu G,Ren X,Liu X,He L,Huang H
Thu Mar 24 00:00:00 EDT 2022
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Genetics research
Lin L,Wang X,Zhao W,Chen Y
Mon Nov 07 00:00:00 EST 2022
FBXL6 depletion restrains clear cell renal cell carcinoma progression.
Translational oncology
Yu Y,Yao W,Wang T,Xue W,Meng Y,Cai L,Jian W,Yu Y,Zhang C
Thu Dec 01 00:00:00 EST 2022
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Frontiers in medicine
Schlichtner S,Yasinska IM,Ruggiero S,Berger SM,Aliu N,Prunk M,Kos J,Meyer NH,Gibbs BF,Fasler-Kan E,Sumbayev VV
Tue Mar 01 00:00:00 EST 2022
Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nature communications
Chen ZP,Xu D,Wang L,Mao YX,Li Y,Cheng MT,Zhou CZ,Hou WT,Chen Y
Wed Jun 08 00:00:00 EDT 2022
The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.
Frontiers in cell and developmental biology
Xiao Z,Liu S,Li Z,Cui J,Wang H,Wang Z,Ren Q,Xia L,Wang Z,Li Y
Tue Jul 26 00:00:00 EDT 2022
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Molecules (Basel, Switzerland)
Li Y,Zhang E,Yang H,Chen Y,Tao L,Xu Y,Chen T,Shen X
Sat Sep 24 00:00:00 EDT 2022
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
British journal of pharmacology
Hu J,Gu W,Ma N,Fan X,Ci X
Mon Aug 01 00:00:00 EDT 2022
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Cell death & disease
Wang D,Wang X,Song Y,Si M,Sun Y,Liu X,Cui S,Qu X,Yu X
Wed Apr 20 00:00:00 EDT 2022
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
Oncology letters
Xu C,Yang HL,Yang YK,Pan L,Chen HY
Sat Jan 01 00:00:00 EST 2022
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Translational oncology
Lin Z,Yang S,Zhou Y,Hou Z,Li L,Meng M,Ge C,Zeng B,Lai J,Gao H,Zhao Y,Xie Y,He S,Tang W,Li R,Tan J,Wang W
Tue Feb 01 00:00:00 EST 2022
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Frontiers in pharmacology
Li Z,Geng J,Xie B,He J,Wang J,Peng L,Hu Y,Dai H,Wang C
Sat Apr 02 00:00:00 EDT 2022
Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis.
Mediators of inflammation
Zhang Y,Yao Z,Xiao Y,Zhang X,Liu J
Tue May 03 00:00:00 EDT 2022
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Bioorganic & medicinal chemistry
Mao PT,He WB,Mai X,Feng LH,Li N,Liao YJ,Zhu CS,Li J,Chen T,Liu SH,Zhang QM,He L
Tue Feb 15 00:00:00 EST 2022
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
Cell reports
Wang Y,Karki R,Mall R,Sharma BR,Kalathur RC,Lee S,Kancharana B,So M,Combs KL,Kanneganti TD
Tue Oct 04 00:00:00 EDT 2022
LPS induces pulmonary microvascular endothelial cell barrier dysfunction by upregulating ceramide production.
Cellular signalling
Jiang J,Ouyang H,Zhou Q,Tang S,Fang P,Xie G,Yang J,Sun G
Fri Apr 01 00:00:00 EDT 2022
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
The Journal of clinical investigation
Li W,Feng W,Su X,Luo D,Li Z,Zhou Y,Zhu Y,Zhang M,Chen J,Liu B,Huang H
Tue Jan 04 00:00:00 EST 2022
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu J,Tong Y,Shen Z,Li Y,Cheng C,Au R,Xu F,Liu Y,Zhu L,Shen H
Sat Oct 01 00:00:00 EDT 2022
Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.
Human molecular genetics
Wang J,Bai J,OuYang S,Wang H,Jin Y,Peng X,Ge X,Jiao H,Zou J,He C,Xiao P,Song F,Qu Y
Thu May 19 00:00:00 EDT 2022
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Life sciences
Liu M,Chen MY,An L,Ma SQ,Mei J,Huang WH,Zhang W
Tue Nov 01 00:00:00 EDT 2022
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Materials today. Bio
Tan C,Fan H,Ding J,Han C,Guan Y,Zhu F,Wu H,Liu Y,Zhang W,Hou X,Tan S,Tang Q
Tue Mar 01 00:00:00 EST 2022
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Cellular signalling
Liu C,Shen L,Xu L,Zhu A,Huang Y
Sat Jan 01 00:00:00 EST 2022
Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate Cancer.
Frontiers in oncology
Wan S,He Y,Zhang B,Yang Z,Du FM,Zhang CP,Fu YQ,Mi J
Sat Jul 16 00:00:00 EDT 2022
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
EMBO reports
Lin Y,Lv X,Sun C,Sun Y,Yang M,Ma D,Jing W,Zhao Y,Cheng Y,Xuan H,Han L
Mon Nov 07 00:00:00 EST 2022
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Journal of medicinal chemistry
Zhang S,Chen X,Wu C,Xu H,Xie X,Feng M,Hu S,Bai H,Gao F,Tong L,Ding J,Liu H,Xie Z,Wang J
Thu Jun 09 00:00:00 EDT 2022
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma.
International journal of biological sciences
Wu Q,Zhang H,Yang D,Min Q,Wang Y,Zhang W,Zhan Q
Mon Aug 22 00:00:00 EDT 2022
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
Cell death and differentiation
Wang Y,Zheng L,Shang W,Yang Z,Li T,Liu F,Shao W,Lv L,Chai L,Qu L,Xu Q,Du J,Liang X,Zeng J,Jia J
Tue Nov 01 00:00:00 EDT 2022
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
The American journal of pathology
Barajas JM,Lin CH,Sun HL,Alencastro F,Zhu AC,Aljuhani M,Navari L,Yilmaz SA,Yu L,Corps K,He C,Duncan AW,Ghoshal K
Sat Jan 01 00:00:00 EST 2022
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Frontiers in nutrition
He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L
Sat Jul 16 00:00:00 EDT 2022
Inhibition of noncaspase proteases, calpain and proteasome, via ALLN and Bortezomib contributes to cell death through low degradation of pro-/anti-apoptotic proteins and apoptosis induction.
Medical oncology (Northwood, London, England)
Hamidi R,Ataei F,Hosseinkhani S
Sat Jun 18 00:00:00 EDT 2022
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
Nutrients
Wang H,Zhang K,Chen X,Han M,Lu J,Zhang Y
Thu Oct 20 00:00:00 EDT 2022
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Oncology letters
Yang B,Huang S,Chen H,Li R,Hou S,Zhao J,Li Y
Sat Jan 01 00:00:00 EST 2022
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Immunological investigations
Li X,Chen C,Zhang L,Cheng X,Geng H,Ji Q,Li C,Chen H,Körner H,Liu X
Sun May 01 00:00:00 EDT 2022
Circ007071 Inhibits Unsaturated Fatty Acid Synthesis by Interacting with miR-103-5p to Enhance PPARγ Expression in the Dairy Goat Mammary Gland.
Journal of agricultural and food chemistry
Chen Z,Lu Q,Zhang X,Zhang Z,Cao X,Wang K,Lu X,Yang Z,Loor JJ,Jiao P
Wed Oct 26 00:00:00 EDT 2022
Sodium-glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.
Frontiers in cardiovascular medicine
Zhan X,Cheng L,Huo N,Yu L,Liu C,Liu T,Li G,Fu H
Sat Sep 24 00:00:00 EDT 2022
Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xia QS,Wu F,Wu WB,Dong H,Huang ZY,Xu L,Lu FE,Gong J
Wed Jun 01 00:00:00 EDT 2022
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Microvascular research
Xu S,Xia X,Liu Y,Chen F,Gu R,Bian X,Xu X,Jia C,Lu S,Gu Y,Bai H,Zhang H
Sun May 01 00:00:00 EDT 2022
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
JCI insight
Sha L,Li G,Zhang X,Lin Y,Qiu Y,Deng Y,Zhu W,Xu Q
Mon Aug 08 00:00:00 EDT 2022
Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression.
Adipocyte
Ge Z,Shang Y,Wang W,Yang J,Chen SZ
Thu Dec 01 00:00:00 EST 2022
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Cell death & disease
Liu H,Wang J,Ding Y,Shi X,Ren H
Sat May 21 00:00:00 EDT 2022
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Biochemical and biophysical research communications
Zhang B,Ma Y,Niu H,Liu Z
Sat Jun 04 00:00:00 EDT 2022
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Molecular immunology
Liu L,Yuan Y,Zhou Y,Yao L,Li J,Chen F
Thu Dec 01 00:00:00 EST 2022
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Epileptic disorders : international epilepsy journal with videotape
Wen F,Zhan Q,Zou T,Tan ZG,Xiang J
Sat Oct 01 00:00:00 EDT 2022
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication.
iScience
Lai X,Yu Y,Xian W,Ye F,Ju X,Luo Y,Dong H,Zhou YH,Tan W,Zhuang H,Li T,Liu X,Ding Q,Xiang K
Fri Apr 15 00:00:00 EDT 2022
IL-1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome.
Veterinary microbiology
Chen D,Xu S,Jiang R,Guo Y,Yang X,Zhang Y,Zhou L,Ge X,Han J,Guo X,Yang H
Sat Oct 01 00:00:00 EDT 2022
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
Science immunology
Karki R,Lee S,Mall R,Pandian N,Wang Y,Sharma BR,Malireddi RS,Yang D,Trifkovic S,Steele JA,Connelly JP,Vishwanath G,Sasikala M,Reddy DN,Vogel P,Pruett-Miller SM,Webby R,Jonsson CB,Kanneganti TD
Fri Aug 26 00:00:00 EDT 2022
Anti-Inflammatory Effects and Molecular Mechanisms of Shenmai Injection in Treating Acute Pancreatitis: Network Pharmacology Analysis and Experimental Verification.
Drug design, development and therapy
He Y,Hu C,Liu S,Xu M,Liang G,Du D,Liu T,Cai F,Chen Z,Tan Q,Deng L,Xia Q
Wed Aug 10 00:00:00 EDT 2022
Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB-R signaling.
Drug development research
Chang L,Kong A,Guo Y,Zhang J,Sun Y,Chen P,Wang X
Thu Sep 01 00:00:00 EDT 2022
Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte-mediated glutamate clearance in the dCA1.
Addiction biology
He T,Li N,Shi P,Xu X,Nie J,Lu X,Yu P,Fan Y,Ge F,Guan X
Sat Jan 01 00:00:00 EST 2022
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Molecular immunology
Yu R,Hou C,Peng Y,Zhu X,Shi C,Huang D,Miao Y,Li Q
Thu Dec 01 00:00:00 EST 2022
Combined exposure of lead and high-fat diet enhanced cognitive decline via interacting with CREB-BDNF signaling in male rats.
Environmental pollution (Barking, Essex : 1987)
Liu R,Bai L,Liu M,Wang R,Wu Y,Li Q,Ba Y,Zhang H,Zhou G,Yu F,Huang H
Fri Jul 01 00:00:00 EDT 2022
Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization.
Cancer cell international
Li H,Yan X,Ou S
Fri Sep 02 00:00:00 EDT 2022
Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization.
Cancer cell international
Li H,Yan X,Ou S
Fri Sep 02 00:00:00 EDT 2022
Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
International immunopharmacology
Lu Y,Zhong W,Liu Y,Chen W,Zhang J,Zeng Z,Huang H,Qiao Y,Wan X,Meng X,Cai S,Dong H
Tue Mar 01 00:00:00 EST 2022
MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3-phospho-BAD pathway.
Cell death discovery
Guan X,Meng X,Zhu K,Kai J,Liu Y,Ma Q,Tong Y,Zheng H,Xie S,Ma X,Wang Y,Lu R,Guo L
Sat Feb 26 00:00:00 EST 2022
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Materials today. Bio
Li J,Luo G,Zhang C,Long S,Guo L,Yang G,Wang F,Zhang L,Shi L,Fu Y,Zhang Y
Tue Mar 01 00:00:00 EST 2022
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice.
Neural regeneration research
Gong QY,Cai L,Jing Y,Wang W,Yang DX,Chen SW,Tian HL
Thu Sep 01 00:00:00 EDT 2022
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
Chemico-biological interactions
Jiang S,Jiang T,Huang H,Chen X,Li L,Wang Z,Fei J,Liu C,Liu Z,Cheng Y
Wed Jan 05 00:00:00 EST 2022
Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3.
Viruses
Gao H,Xiang Z,Ge X,Zhou L,Han J,Guo X,Chen Y,Zhang Y,Yang H
Thu Apr 21 00:00:00 EDT 2022
Highly efficient A-to-G base editing by ABE8.17 in rabbits.
Molecular therapy. Nucleic acids
Zhao D,Qian Y,Li J,Li Z,Lai L
Tue Mar 08 00:00:00 EST 2022
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Frontiers in molecular neuroscience
Lu Y,Li B,Xu A,Liang X,Xu T,Jin H,Xie Y,Wang R,Liu X,Gao X,Han Y,Zeng J
Tue Aug 16 00:00:00 EDT 2022
Ban-xia-xie-xin-tang ameliorates hepatic steatosis by regulating Cidea and Cidec expression in HFD-fed mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xia QS,Gao Y,Wen-Bin W,Wu F,Dong H,Xu LJ,Fang K,Hu ML,Yuan F,Lu FE,Gong J
Sat Oct 01 00:00:00 EDT 2022
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Reproductive toxicology (Elmsford, N.Y.)
Gu X,Liu H,Luo W,Wang X,Wang H,Li L
Thu Dec 01 00:00:00 EST 2022
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.
European journal of pharmacology
Zheng X,Pan Y,Yang G,Liu Y,Zou J,Zhao H,Yin G,Wu Y,Li X,Wei Z,Yu S,Zhao Y,Wang A,Chen W,Lu Y
Thu Sep 15 00:00:00 EDT 2022
EGFR Activation Impairs Antiviral Activity of Interferon Signaling in Brain Microvascular Endothelial Cells During Japanese Encephalitis Virus Infection.
Frontiers in microbiology
Zhang YG,Chen HW,Zhang HX,Wang K,Su J,Chen YR,Wang XR,Fu ZF,Cui M
Tue Jul 19 00:00:00 EDT 2022
Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B-Lamin B1 Interaction in Alcoholic Fatty Liver Disease.
Frontiers in pharmacology
Qi X,Zheng S,Ma M,Lian N,Wang H,Chen L,Song A,Lu C,Zheng S,Jin H
Sat Jul 16 00:00:00 EDT 2022
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
International journal of biological macromolecules
Zhang D,Chang R,Ren Y,He Y,Guo S,Guan F,Yao M
Mon Oct 31 00:00:00 EDT 2022
Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis.
Lasers in medical science
Dos Anjos LMJ,Quirino-Teixeira AC,Hottz ED,da Fonseca AS,Gameiro J,de Paoli F
Thu Dec 01 00:00:00 EST 2022
SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells.
Medical oncology (Northwood, London, England)
Tang L,Peng L,Liu H,Xiao T,Gu W,Yang H,Wang H,Chen P
Thu Sep 29 00:00:00 EDT 2022
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Evidence-based complementary and alternative medicine : eCAM
Hu Z,Wen T,Hu K,Wang R,Su X,Ouyang W,Zhou J,Wen Y
Sat Jul 16 00:00:00 EDT 2022
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Frontiers in pharmacology
Zhang R,Xie L,Wu F,Xu J,Lu L,Cao L,Li L,Meng W,Zhang H,Shao C,Li X,Chen D
Tue Mar 29 00:00:00 EDT 2022
GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.
Cells
Zhang B,Chen Y,Bao L,Luo W
Sat Aug 20 00:00:00 EDT 2022
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Liu T,Zhang Z,Wang C,Huang H,Li Y
Fri Apr 01 00:00:00 EDT 2022
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Frontiers in immunology
Deng S,Chen X,Lei Q,Lu W
Fri Apr 08 00:00:00 EDT 2022
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
EBioMedicine
Hou Z,Ding Q,Li Y,Zhao Z,Yan F,Li Y,Wang X,Xu J,Chen W,Wu G,Ruan X,Zhao L
Mon Aug 01 00:00:00 EDT 2022
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
iScience
Tian H,Chen Z,Zhu X,Ou Q,Wang Z,Wu B,Xu JY,Jin C,Gao F,Wang J,Zhang J,Zhang J,Lu L,Xu GT
Fri Oct 21 00:00:00 EDT 2022
E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury.
International journal of molecular sciences
Gao Y,Xiao X,Luo J,Wang J,Peng Q,Zhao J,Jiang N,Zhao Y
Mon Nov 07 00:00:00 EST 2022
C1632 suppresses the migration and proliferation of non-small-cell lung cancer cells involving LIN28 and FGFR1 pathway.
Journal of cellular and molecular medicine
Chen JY,Chen YJ,Liu L,Jin XX,Shen Z,Chen WB,Yang T,Xu SB,Wang GB,Cheng YN,Cheng DZ,Liu ZG,Zheng XH
Sat Jan 01 00:00:00 EST 2022
Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis.
Antioxidants (Basel, Switzerland)
Li M,Hu W,Wang R,Li Z,Yu Y,Zhuo Y,Zhang Y,Wang Z,Qiu Y,Chen K,Ding Q,Qi W,Zhu M,Zhu Y
Thu Apr 07 00:00:00 EDT 2022
Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.
Veterinary research
Wang X,Liu M,Geng N,Du Y,Li Z,Gao X,Han B,Liu J,Liu Y
Sat Feb 05 00:00:00 EST 2022
Effects of Excessive Activation of N-methyl-D-aspartic Acid Receptors in Neonatal Cardiac Mitochondrial Dysfunction Induced by Intrauterine Hypoxia.
Frontiers in cardiovascular medicine
Liu Y,Luo Z,Liao Z,Wang M,Zhou Y,Luo S,Ding Y,Liu T,Cao C,Yue S
Sat Jul 16 00:00:00 EDT 2022
Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis.
Frontiers in pharmacology
Kang L,Li D,Jiang X,Zhang Y,Pan M,Hu Y,Si L,Zhang Y,Huang J
Sat Jul 16 00:00:00 EDT 2022
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Oncogene
Wang C,Long Q,Fu Q,Xu Q,Fu D,Li Y,Gao L,Guo J,Zhang X,Lam EW,Campisi J,Sun Y
Tue Nov 01 00:00:00 EDT 2022
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
The Kaohsiung journal of medical sciences
Zhou B,Lei JH,Wang Q,Qu TF,Cha LC,Zhan HX,Liu SL,Hu X,Sun CD,Guo WD,Qiu FB,Cao JY
Tue Nov 01 00:00:00 EDT 2022
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Frontiers in endocrinology
Zhan Z,Li A,Zhang W,Wu X,He J,Li Z,Li Y,Sun J,Zhang H
Tue Dec 27 00:00:00 EST 2022
EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.
Cell death & disease
Song S,Yu Z,You Y,Liu C,Xie X,Lv H,Xiao F,Zhu Q,Qin C
Fri Apr 15 00:00:00 EDT 2022
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Experimental cell research
Duan SF,Zhang MM,Zhang X,Liu W,Zhang SH,Yang B,Dong Q,Han JG,Yu HL,Li T,Ji XY,Wu DD,Zhang XJ
Tue Nov 01 00:00:00 EDT 2022
Preparation of curcumin-loaded cochleates: characterisation, stability and antioxidant properties.
Food & function
Chen L,Yue B,Liu Z,Luo Y,Ni L,Shen W,Zhou Z,Ge X
Mon Oct 31 00:00:00 EDT 2022
Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.
Frontiers in pharmacology
Cheng Z,Luo X,Zhu Z,Huang Y,Yan X
Sat Jul 16 00:00:00 EDT 2022
Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer.
Cell death discovery
Zhang Z,Xue ST,Gao Y,Li Y,Zhou Z,Wang J,Li Z,Liu Z
Thu Jun 09 00:00:00 EDT 2022
Protective Effect of Ginsenosides from Stems and Leaves of Panax ginseng against Scopolamine-Induced Memory Damage via Multiple Molecular Mechanisms.
The American journal of Chinese medicine
Wang Y,Zhang JJ,Hou JG,Li X,Liu W,Zhang JT,Zheng SW,Su FY,Li W
Thu Jun 23 00:00:00 EDT 2022
Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Journal of ethnopharmacology
Jiang H,Xu F,Zeng L,Li C,Chen Y,Wang L,Li Z,Liu R
Sun Jan 30 00:00:00 EST 2022
Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.
Frontiers in pharmacology
Yang S,Cao S,Li C,Zhang J,Liu C,Qiu F,Kang N
Tue Jul 26 00:00:00 EDT 2022
Sema3A accelerates bone formation during distraction osteogenesis in mice.
Connective tissue research
Zhang N,Hua Y,Li Y,Pan J
Fri Jul 01 00:00:00 EDT 2022
Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer's Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation.
Molecular neurobiology
Zhou C,Jung CG,Kim MJ,Watanabe A,Abdelhamid M,Taslima F,Michikawa M
Thu Sep 01 00:00:00 EDT 2022
The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice.
Cellular and molecular gastroenterology and hepatology
Mao XT,Zou WB,Cao Y,Wang YC,Deng SJ,Cooper DN,Férec C,Li ZS,Chen JM,Liao Z
Mon Jun 20 00:00:00 EDT 2022
Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism.
Pharmacological reports : PR
Sato I,Yamamoto S,Kakimoto M,Fujii M,Honma K,Kumazaki S,Matsui M,Nakayama H,Kirihara S,Ran S,Usui S,Shinohata R,Kitamori K,Hirohata S,Watanabe S
Mon Aug 01 00:00:00 EDT 2022
Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.
Frontiers of medicine
Yang Y,Li G,Wang Y,Sun Y,Xu C,Wei Z,Zhang S,Gao L,Liu S,Zhao J
Thu Dec 01 00:00:00 EST 2022
Novel phosphanegold(I) thiolate complexes suppress de novo lipid synthesis in human lung cancer.
European journal of medicinal chemistry
Luo M,Ma X,Jiang W,Zhang J,Liu W,Wei S,Liu H
Tue Mar 15 00:00:00 EDT 2022
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Journal of immunology research
Zhang M,Wang XL,Shi H,Meng LQ,Quan HF,Yan L,Yang HF,Peng XD
Thu Nov 10 00:00:00 EST 2022
HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
Journal of neurovirology
Zhou X,Zhou S,Tao J,Gao Y,Meng G,Cao D,Gao L
Thu Dec 01 00:00:00 EST 2022
Large Yellow Tea Extract Ameliorates Metabolic Syndrome by Suppressing Lipogenesis through SIRT6/SREBP1 Pathway and Modulating Microbiota in Leptin Receptor Knockout Rats.
Foods (Basel, Switzerland)
Wu G,Sun X,Cheng H,Xu S,Li D,Xie Z
Wed Jun 01 00:00:00 EDT 2022
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.
Atherosclerosis plus
Wang Z,Li G,Li M,Hu L,Hao Z,Li Q,Sun C
Thu Dec 01 00:00:00 EST 2022
Sufentanil Alleviates Sepsis-Induced Myocardial Injury and Stress Response in Rats through the ERK/GSK-3β Signaling Axis.
Evidence-based complementary and alternative medicine : eCAM
Zang H,Shao G,Lou Y
Fri Aug 11 00:00:00 EDT 2023
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Ecotoxicology and environmental safety
Wu J,Yang C,Yang M,Liang Z,Wu Y,Kong X,Fan H,Wang S,Ning C,Xiao W,Jin Y,Yi J,Yuan Z
Wed Jun 01 00:00:00 EDT 2022
CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy
Ma Y,Kang B,Li S,Xie G,Bi J,Li F,An G,Liu B,Li J,Shen Y,Xu X,Yang H,Yang Y,Gu Y,Wu N
Wed Nov 02 00:00:00 EDT 2022
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.
Molecular therapy oncolytics
Wang M,Liu K,Bu H,Cong H,Dong G,Xu N,Li C,Zhao Y,Jiang F,Zhang Y,Yuan B,Li R,Jiang J
Thu Sep 15 00:00:00 EDT 2022
7-O-(2- (Propylamino)-2-oxoethyl) hesperetin attenuates inflammation and protects against alcoholic liver injury by NLRP12.
International immunopharmacology
Niu XN,Zhang YL,Cheng M,Yin NN,Wu YY,Shi W,Yang YL,Zhu L,Huang C,Li J
Thu Sep 01 00:00:00 EDT 2022
SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma.
International journal of molecular sciences
Huang CY,Chen LJ,Chen G,Chao TI,Wang CY
Wed Sep 21 00:00:00 EDT 2022
Androgen receptor splicing variant 7 (ARv7) promotes DNA damage response in prostate cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Luo H,Liu Y,Li Y,Zhang C,Yu B,Shao C
Thu Sep 01 00:00:00 EDT 2022
UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.
Cell cycle (Georgetown, Tex.)
Huang W,Huang H,Xiao Y,Wang L,Zhang T,Fang X,Xia X
Fri Apr 01 00:00:00 EDT 2022
M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.
Neural regeneration research
Yu SS,Li ZY,Xu XZ,Yao F,Luo Y,Liu YC,Cheng L,Zheng MG,Jing JH
Sun May 01 00:00:00 EDT 2022
The NS4A Protein of Classical Swine Fever Virus Suppresses RNA Silencing in Mammalian Cells.
Journal of virology
Qian Q,Xu R,Wang Y,Ma L
Wed Aug 10 00:00:00 EDT 2022
MicroRNA-124 attenuates PTSD-like behaviors and reduces the level of inflammatory cytokines by downregulating the expression of TRAF6 in the hippocampus of rats following single-prolonged stress.
Experimental neurology
Chen Y,An Q,Yang ST,Chen YL,Tong L,Ji LL
Sat Oct 01 00:00:00 EDT 2022
Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways.
Frontiers in pharmacology
Shi YL,Zhang YP,Luo H,Xu F,Gao JM,Shi JS,Gong QH
Wed Feb 16 00:00:00 EST 2022
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Scientific reports
Ding K,Li D,Zhang R,Zuo M
Tue Aug 30 00:00:00 EDT 2022
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Chinese medicine
Qi W,Li X,Ren Y,Liu X,Fu H,Wang X,Li X,Xiong J,Zheng Q,Cai D,Liang F
Tue May 17 00:00:00 EDT 2022
PGC-1α attenuates TNF-α-induced inflammatory responses in OCCM-30 cells.
Journal of periodontal research
Fu Y,Du M,Cao Z,He H
Sat Oct 01 00:00:00 EDT 2022
20(S)-Protopanaxadiol decreases atherosclerosis in ApoE KO mice by increasing the levels of LDLR and inhibiting its binding with PCSK9.
Food & function
Huang YW,Zhang M,Wang LT,Nie Y,Yang JB,Meng WL,Wang XJ,Sheng J
Mon Jul 04 00:00:00 EDT 2022
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
International journal of nanomedicine
Fu Y,Yuan P,Zheng Y,Wei Y,Gao L,Ruan Y,Chen Y,Li P,Feng W,Zheng X
Tue Apr 12 00:00:00 EDT 2022
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Free radical biology & medicine
Li T,Geng Z,Zhang J,Xu L,Zhu X
Sun Nov 20 00:00:00 EST 2022
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Nature communications
Zhang J,Gan Y,Li H,Yin J,He X,Lin L,Xu S,Fang Z,Kim BW,Gao L,Ding L,Zhang E,Ma X,Li J,Li L,Xu Y,Horne D,Xu R,Yu H,Gu Y,Huang W
Fri May 20 00:00:00 EDT 2022
MDM2-mediated ubiquitination of LKB1 contributes to the development of diabetic cataract.
Experimental cell research
Li X,Sun X,Li L,Luo Y,Chi Y,Zheng G
Mon Aug 01 00:00:00 EDT 2022
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Nature communications
Zhang W,Yang X,Li Y,Yu L,Zhang B,Zhang J,Cho WJ,Venkatarangan V,Chen L,Burugula BB,Bui S,Wang Y,Duan C,Kitzman JO,Li M
Mon Sep 12 00:00:00 EDT 2022
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
Nature communications
Li Y,Zhang L,Wang Y,Zou J,Yang R,Luo X,Wu C,Yang W,Tian C,Xu H,Wang F,Yang X,Li L,Yang S
Sat Nov 12 00:00:00 EST 2022
MxB inhibits long interspersed element type 1 retrotransposition.
PLoS genetics
Huang Y,Xu F,Mei S,Liu X,Zhao F,Wei L,Fan Z,Hu Y,Wang L,Ai B,Cen S,Liang C,Guo F
Tue Feb 01 00:00:00 EST 2022
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Aging
Zuo L,Zhu Y,Han J,Liu H
Thu Feb 24 00:00:00 EST 2022
SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers.
Frontiers in immunology
Ji W,Niu X,Yu Y,Li Z,Gu L,Lu S
Tue Nov 22 00:00:00 EST 2022
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
Cell reports
Yang D,Liu H,Cai Y,Lu K,Zhong X,Xing S,Song W,Zhang Y,Ye L,Zhu X,Wang T,Zhang P,Li ST,Feng J,Jia W,Zhang H,Gao P
Tue Nov 22 00:00:00 EST 2022
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.
Journal of oncology
Hu Y,Zai H,Jiang W,Ou Z,Yao Y,Zhu Q
Sat Mar 19 00:00:00 EDT 2022
Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.
Frontiers in immunology
Chen R,Zhang H,Wu W,Li S,Wang Z,Dai Z,Liu Z,Zhang J,Luo P,Xia Z,Cheng Q
Fri Apr 15 00:00:00 EDT 2022
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.
International journal of biological sciences
Liu Y,Tian H,Hu Y,Cao Y,Song H,Lan S,Dai Z,Chen W,Zhang Y,Shao Z,Liu Y,Tong W
Tue Jul 19 00:00:00 EDT 2022
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.
International journal of biological sciences
Liu Y,Tian H,Hu Y,Cao Y,Song H,Lan S,Dai Z,Chen W,Zhang Y,Shao Z,Liu Y,Tong W
Tue Jul 19 00:00:00 EDT 2022
Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis.
Frontiers in pharmacology
Hong M,Wu Y,Zhang H,Gu J,Chen J,Guan Y,Qin X,Li Y,Cao J
Tue Sep 13 00:00:00 EDT 2022
High-Calcium Microenvironment during the Development of Kidney Calculi Can Promote Phenotypic Transformation of NRK-52E Cells by Inhibiting the Expression of Stromal Interaction Molecule-1.
BioMed research international
Li LS,Zhu YP,Xia QD,Wang SG,He D
Fri Apr 08 00:00:00 EDT 2022
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
PloS one
Sun J,Zhang W
Wed May 04 00:00:00 EDT 2022
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Oxidative medicine and cellular longevity
Han GJ,Min XZ,Ma SS,Ding C,Wang XQ
Tue Dec 20 00:00:00 EST 2022
TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang N,Huang R,Zhang J,Xu D,Li T,Sun Z,Su L,Peng Z
Fri Apr 01 00:00:00 EDT 2022
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
International journal of molecular sciences
Xu Z,Hao X,Li M,Luo H
Sun Aug 28 00:00:00 EDT 2022
LncRNA LINC00152 promotes oral squamous cell carcinoma growth via enhancing Upstream Transcription Factor 1 mediated Mitochondrial Ribosomal Protein L52 transcription.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Zou X,Hu X,He F,Zhang M,Kong X,Rui S,Liu Y,Wang L,Zheng X,Liu J,Li Z,Luo H
Sun May 01 00:00:00 EDT 2022
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Frontiers in pharmacology
Chai Y,Cai Y,Fu Y,Wang Y,Zhang Y,Zhang X,Zhu L,Miao M,Yan T
Sat Jul 16 00:00:00 EDT 2022
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.
Journal of experimental & clinical cancer research : CR
Zhang J,Li Y,Liu H,Zhang J,Wang J,Xia J,Zhang Y,Yu X,Ma J,Huang M,Wang J,Wang L,Li Q,Cui R,Yang W,Xu Y,Feng W
Sat Jan 15 00:00:00 EST 2022
Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.
Nature communications
Xu D,Ma R,Ju Y,Song X,Niu B,Hong W,Wang R,Yang Q,Zhao Z,Zhang Y,Zheng Y,Bai Q,Lv M,Sun N,Li X
Sat Jul 30 00:00:00 EDT 2022
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Journal of neuroinflammation
Chen B,Qin G,Xiao J,Deng X,Lin A,Liu H
Wed Jul 13 00:00:00 EDT 2022
Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.
iScience
Zhang H,Zhang N,Wu W,Wang Z,Dai Z,Liang X,Zhang L,Peng Y,Luo P,Zhang J,Liu Z,Cheng Q,Liu Z
Fri Sep 16 00:00:00 EDT 2022
Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.
International journal of biological sciences
Wang J,Yang P,Yu T,Gao M,Liu D,Zhang J,Lu C,Chen X,Zhang X,Liu Y
Tue Nov 29 00:00:00 EST 2022
CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice.
Journal of translational medicine
Ren M,Pan J,Yu X,Chang K,Yuan X,Zhang C
Tue Oct 04 00:00:00 EDT 2022
An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.
Acta pharmacologica Sinica
Hu XX,Zhang AJ,Pan WW,Xin QL,Chen JY,Zhang LL,Chang Y,Wu YJ,Wei W
Tue Feb 01 00:00:00 EST 2022
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages.
Archives of pharmacal research
Lee S,Pham DV,Park PH
Sat Jan 01 00:00:00 EST 2022
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Biochemical pharmacology
Gu H,Li Y,Cui X,Cao H,Hou Z,Ti Y,Liu D,Gao J,Wang Y,Wen P
Sat Jan 01 00:00:00 EST 2022
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Journal of periodontal research
Cai J,Liu J,Yan J,Lu X,Wang X,Li S,Mustafa K,Wang H,Xue Y,Mustafa M,Kantarci A,Xing Z
Sat Oct 01 00:00:00 EDT 2022
GDNF Promotes Astrocyte Abnormal Proliferation and Migration Through the GFRα1/RET/MAPK/pCREB/LOXL2 Signaling Axis.
Molecular neurobiology
Wang M,Han X,Zha W,Wang X,Liu L,Li Z,Shi Y,Kan X,Wang G,Gao D,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Metabolomics Analysis of the Prefrontal Cortex in a Rat Chronic Unpredictable Mild Stress Model of Depression.
Frontiers in psychiatry
Duan L,Fan R,Li T,Yang Z,Hu E,Yu Z,Tian J,Luo W,Zhang C
Tue Apr 05 00:00:00 EDT 2022
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang YF,Chang YY,Zhang XM,Gao MT,Zhang QL,Li X,Zhang L,Yao WF
Sun May 01 00:00:00 EDT 2022
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Frontiers in immunology
Zong F,Li S,Wang Y,Xiao N,Deng M,Zhang Z,Su D,Gao B,Zhou D,Hu L,Yang H
Mon Oct 10 00:00:00 EDT 2022
Temporal Dynamics of the Ruminant Type I IFN-Induced Antiviral State against Homologous Parainfluenza Virus 3 Challenge In Vitro.
Viruses
Sun M,Hao F,Li W,Cheng Z,Zhang W,Yang L,Mao L,Liu M
Wed May 11 00:00:00 EDT 2022
HBO1 catalyzes lysine benzoylation in mammalian cells.
iScience
Tan D,Wei W,Han Z,Ren X,Yan C,Qi S,Song X,Zheng YG,Wong J,Huang H
Fri Nov 18 00:00:00 EST 2022
OPN5 Regulating Mechanism of Follicle Development Through the TSH-DIO2/DIO3 Pathway in Mountain Ducks Under Different Photoperiods.
Frontiers in physiology
Liufu S,Pan J,Sun J,Shen X,Jiang D,Ouyang H,Xu D,Tian Y,Huang Y
Sat Jul 16 00:00:00 EDT 2022
Deubiquitination of BES1 by UBP12/UBP13 promotes brassinosteroid signaling and plant growth.
Plant communications
Park SH,Jeong JS,Zhou Y,Binte Mustafa NF,Chua NH
Mon Sep 12 00:00:00 EDT 2022
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
BMC neuroscience
Yang RC,Huang K,Zhang HP,Li L,Tan C,Chen HC,Jin ML,Wang XR
Wed Jul 06 00:00:00 EDT 2022
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
Oxidative medicine and cellular longevity
Zuo X,Wei X,Ju C,Wang X,Zhang Z,Ma Y,Zhu Z,Li X,Song Z,Luo L,Hu X,Wang Z
Mon Dec 05 00:00:00 EST 2022
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Biochemical and biophysical research communications
Wang W,Yu S,Li W,Hu H,Zou G
Sat Dec 31 00:00:00 EST 2022
Electroacupuncture Preconditioning Alleviates Lipopolysaccharides-Induced Acute Lung Injury by Downregulating LC3-II/I and Beclin 1 Expression.
Evidence-based complementary and alternative medicine : eCAM
Sun G,Zeng Y,Luo F,Zhang L,Tan J,Tong J,Yang L,Liu D,Liu L,Zhou J
Wed Nov 02 00:00:00 EDT 2022
Targeting BCAT1 Combined with α-Ketoglutarate Triggers Metabolic Synthetic Lethality in Glioblastoma.
Cancer research
Zhang B,Peng H,Zhou M,Bao L,Wang C,Cai F,Zhang H,Wang JE,Niu Y,Chen Y,Wang Y,Hatanpaa KJ,Copland JA,DeBerardinis RJ,Wang Y,Luo W
Tue Jul 05 00:00:00 EDT 2022
Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction.
Gene
Sahashi D,Kubo Y,Ishii M,Ikeda A,Yamasaki C,Komatsu M,Shiozaki K
Sat Aug 20 00:00:00 EDT 2022
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Journal of plastic surgery and hand surgery
Dong X,Zhang M,Chen Y,Li C,Wang Y,Jin X
Fri Apr 01 00:00:00 EDT 2022
TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.
Leukemia & lymphoma
Man J,Wang H,Qian X,Chen L,Ma Y,Qian M,Zhai X
Sat Oct 01 00:00:00 EDT 2022
Coxsackievirus Group B3 Has Oncolytic Activity against Colon Cancer through Gasdermin E-Mediated Pyroptosis.
Cancers
Zhang Y,Xu T,Tian H,Wu J,Yu X,Zeng L,Liu F,Liu Q,Huang X
Thu Dec 15 00:00:00 EST 2022
Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.
Journal of orthopaedic surgery (Hong Kong)
Zhang C,Li Z,Li L,Li S,Yang L,Chen L,Zhang X,Yang S,Guo Y
Tue Nov 01 00:00:00 EDT 2022
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Biology direct
Peng T,Liu M,Hu L,Guo D,Wang D,Qi B,Ren G,Hu C,Zhang F,Chun HJ,Song L,Hu J,Li Y
Wed Nov 16 00:00:00 EST 2022
Microbial and metabolic profiles of bronchopulmonary dysplasia and therapeutic effects of potential probiotics Limosilactobacillus reuteri and Bifidobacterium bifidum.
Journal of applied microbiology
Li Y,He L,Zhao Q,Bo T
Mon Aug 01 00:00:00 EDT 2022
Bisacodyl Limits Chikungunya Virus Replication In Vitro and Is Broadly Antiviral.
Antimicrobial agents and chemotherapy
LoMascolo NJ,Cruz-Pulido YE,Mounce BC
Tue Jun 21 00:00:00 EDT 2022
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Cytotechnology
Liu Y,Lai S,He J,Wan J,Fu F,Jinlong Y
Wed Jun 01 00:00:00 EDT 2022
Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation.
Ecotoxicology and environmental safety
Yang Y,Liu Y,Zhang AL,Tang SF,Ming Q,Ao CY,Liu Y,Li CZ,Yu C,Zhao H,Chen L,Li J
Sun May 01 00:00:00 EDT 2022
Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis regulation.
Aging
Ren X,Wang X,Yan Y,Chen X,Cai Y,Liang Q,Peng B,Xu Z,He Q,Kang F,Li J,Zhang W,Hong Q,Peng J,Xiao M
Tue Jan 25 00:00:00 EST 2022
Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.
Journal of nanobiotechnology
Zhao N,Gui X,Fang Q,Zhang R,Zhu W,Zhang H,Li Q,Zhou Y,Zhao J,Cui X,Gao G,Tang H,Shen N,Chen T,Song H,Shen W
Sat Apr 02 00:00:00 EDT 2022
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Journal of virology
Cui M,Zhao Q,Wang J,Si Y,Cheng S,Ding W
Wed Feb 09 00:00:00 EST 2022
A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
Drug delivery
He S,Zhao C,Tao H,Sheng W,Gao R,Liu X,Zhen Y
Thu Dec 01 00:00:00 EST 2022
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Journal of ethnopharmacology
Zhou GQ,Chen G,Yang J,Qin WY,Ping J
Sun Jan 30 00:00:00 EST 2022
Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction.
Nature communications
Cheng J,Zhang S,Li C,Li K,Jia X,Wei Q,Qi H,Zhang J
Tue Nov 22 00:00:00 EST 2022
Arsenic exposure increases susceptibility to Ptpn11-induced malignancy in mouse embryonic fibroblasts through mitochondrial hypermetabolism.
American journal of translational research
Yang F,Tan Z,Dai Y,Wang X,Huang Z,Kan C,Wang S
Sat Aug 13 00:00:00 EDT 2022
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.
Molecular therapy. Nucleic acids
Hu M,Zheng Y,Liao J,Wen L,Cheng J,Huang J,Huang B,Lin L,Long Y,Wu Y,Ye X,Fu Y,Qi H,Baker PN,Tong C
Tue Dec 13 00:00:00 EST 2022
Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway.
Cell communication and signaling : CCS
Pan J,Sheng S,Ye L,Xu X,Ma Y,Feng X,Qiu L,Fan Z,Wang Y,Xia X,Zheng JC
Wed Jan 12 00:00:00 EST 2022
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Journal of medicinal chemistry
Wang A,Luo X,Wang Y,Meng X,Lu Z,Yang Y
Thu Sep 22 00:00:00 EDT 2022
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Biochimica et biophysica acta. Molecular cell research
Li J,Sun Y,Yan R,Wu X,Zou H,Meng Y
Sun May 01 00:00:00 EDT 2022
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Life sciences
Xu M,Ren L,Fan J,Huang L,Zhou L,Li X,Ye X
Tue Feb 01 00:00:00 EST 2022
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Biomedicines
Ho ML,Hsu CJ,Wu CW,Chang LH,Chen JW,Chen CH,Huang KC,Chang JK,Wu SC,Shao PL
Thu Jul 21 00:00:00 EDT 2022
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.
Microbiome
Wang L,Liu Q,Chen Y,Zheng X,Wang C,Qi Y,Dong Y,Xiao Y,Chen C,Chen T,Huang Q,Zhai Z,Long C,Yang H,Li J,Wang L,Zhang G,Liao P,Liu YX,Huang P,Huang J,Wang Q,Chu H,Yin J,Yin Y
Wed Jun 01 00:00:00 EDT 2022
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Technology in cancer research & treatment
Zhang H,Yin X,Zhang X,Zhou M,Xu W,Wei Z,Song C,Han S,Han W
Mon Aug 08 00:00:00 EDT 2022
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Molecules (Basel, Switzerland)
Zhou M,Dai Y,Ma Y,Yan Y,Hua M,Gao Q,Geng X,Zhou Q
Tue Jun 14 00:00:00 EDT 2022
A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model.
Frontiers in pharmacology
Fan X,Li X,Liu H,Xu F,Ji X,Chen Y,Li C
Sat Jul 23 00:00:00 EDT 2022
Differential expression of long non-coding RNAs in the hippocampus of mice exposed to PM2.5 in Dalian, China.
Environmental science and pollution research international
Li J,Zhang L,Wang J,Jia R,Zhang X,Li X,Fu Y,Song L
Tue Feb 01 00:00:00 EST 2022
Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection.
Journal of inflammation research
Wang F,Yang Y,Li Z,Wang Y,Zhang Z,Zhang W,Mu Y,Yang J,Yu L,Wang M
Sat Mar 19 00:00:00 EDT 2022
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Bone
He Y,Wang W,Xu X,Yang B,Yu X,Wu Y,Wang J
Sat Jan 01 00:00:00 EST 2022
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.
Cancers
Lee Y,Wu Z,Yang S,Schreiner SM,Gonzalez-Smith LD,Rhie SK
Tue Oct 11 00:00:00 EDT 2022
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
International journal of biological sciences
Wu X,Wei S,Chen M,Li J,Wei Y,Zhang J,Dong W
Mon Aug 22 00:00:00 EDT 2022
Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase.
Bioorganic & medicinal chemistry
Wang H,Li C,Liu X,Ma M
Sun May 01 00:00:00 EDT 2022
Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.
Translational oncology
Tan W,Zhang J,Liu L,Liang M,Li J,Deng Z,Zheng Z,Deng Y,Liu C,Li Y,Xie G,Zhang J,Zou F,Chen X
Thu Dec 01 00:00:00 EST 2022
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
Hypertension research : official journal of the Japanese Society of Hypertension
He Y,Su H,Li N,Zhang Y,Zhang P,Zhang Y,Ye Y,Zhang Y,Tang J,Xu Z
Fri Jul 01 00:00:00 EDT 2022
TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway.
Reproductive biology and endocrinology : RB&E
Fu H,Tan W,Chen Z,Ye Z,Duan Y,Huang J,Qi H,Liu X
Thu Sep 22 00:00:00 EDT 2022
Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.
Cells
Zrimšek M,Kuchaříková H,Draganić K,Dobrovolná P,Heiss Spornberger V,Winkelmayer L,Hassler MR,Lochmanová G,Zdráhal Z,Egger G
Tue Aug 02 00:00:00 EDT 2022
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Biochemical genetics
Li X,Jiang X,Lu J,Lin Y,Jiang L,Li Y,Wan F,Wang C
Thu Dec 01 00:00:00 EST 2022
Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.
Nucleic acids research
Qin S,Yuan Y,Huang X,Tan Z,Hu X,Liu H,Pu Y,Ding YQ,Su Z,He C
Fri Sep 09 00:00:00 EDT 2022
Expression profiles of exosomal tRNA-derived fragments and their biological functions in lipomas.
Frontiers in cell and developmental biology
Zhou Y,Tao D,Shao Z,Wang X,Xu J,Li Y,Li K
Tue Aug 30 00:00:00 EDT 2022
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.
Journal of colloid and interface science
Chen J,Qiu M,Zhang S,Li B,Li D,Huang X,Qian Z,Zhao J,Wang Z,Tang D
Sat Jan 01 00:00:00 EST 2022
The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis.
Frontiers in genetics
Ye X,Fu Q,Xiao H
Sat Jul 16 00:00:00 EDT 2022
Linagliptin ameliorates pulmonary fibrosis in systemic sclerosis mouse model via inhibition of endothelial-to-mesenchymal transition.
Molecular and cellular biochemistry
Pei B,Zhang N,Pang T,Sun G
Fri Apr 01 00:00:00 EDT 2022
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Pharmaceutical biology
He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X
Thu Dec 01 00:00:00 EST 2022
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
The Journal of investigative dermatology
Padhi A,Srivastava A,Ramesh A,Ehrström M,Simon M,Sonkoly E,Eidsmo L,Bergman P,Lysell J
Tue Feb 01 00:00:00 EST 2022
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.
Experimental eye research
Zhang MY,Zhu L,Bao X,Xie TH,Cai J,Zou J,Wang W,Gu S,Li Y,Li HY,Yao Y,Wei TT
Fri Jul 01 00:00:00 EDT 2022
Deleterious variants in TAF7L cause human oligoasthenoteratozoospermia and its impairing histone to protamine exchange inducing reduced in vitro fertilization.
Frontiers in endocrinology
Bai H,Sha Y,Tan Y,Li P,Zhang Y,Xu J,Xu S,Ji Z,Wang X,Chen W,Zhang J,Yao C,Li Z,Zhi E
Thu Feb 02 00:00:00 EST 2023
The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway.
World journal of gastroenterology
Liu JJ,Xu Y,Chen S,Hao CF,Liang J,Li ZL
Sun Aug 28 00:00:00 EDT 2022
Polysaccharides From the Aerial Parts of Tetrastigma Hemsleyanum Diels et Gilg Induce Bidirectional Immunity and Ameliorate LPS-Induced Acute Respiratory Distress Syndrome in Mice.
Frontiers in pharmacology
Lu J,Zhu B,Zhou F,Ding X,Qian C,Ding Z,Ye X
Tue Apr 05 00:00:00 EDT 2022
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
Cell death & disease
Wan S,Sun Y,Fu J,Song H,Xiao Z,Yang Q,Wang S,Yu G,Feng P,Lv W,Luo L,Guan Z,Liu F,Zhou Q,Yin Z,Yang M
Tue Oct 11 00:00:00 EDT 2022
The double-edged sword role of TGF-β signaling pathway between intrauterine inflammation and cranial neural crest development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li H,Long D,Lv G,Cheng X,Wang G,Yang X
Sat Jan 01 00:00:00 EST 2022
Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages.
International journal of molecular sciences
Ohya S,Matsui M,Kajikuri J,Kito H,Endo K
Wed Aug 03 00:00:00 EDT 2022
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
Pathology, research and practice
Zhang T,Zheng J,Qiao L,Zhao W
Sat Jan 01 00:00:00 EST 2022
Agrimoniin sensitizes pancreatic cancer to apoptosis through ROS-mediated energy metabolism dysfunction.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhu X,Zhang Y,Wang Y,Zhang H,Wang X,Tang H,Huang H,Zhou Z,Chen B,Sun L
Tue Feb 01 00:00:00 EST 2022
Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages.
BMC complementary medicine and therapies
He C,Wang Y,Wen Y,Li T,Hu E,Zeng S,Xiong X
Wed Jul 13 00:00:00 EDT 2022
Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.
BMC cancer
Wang X,Wang Y,Xie F,Song ZT,Zhang ZQ,Zhao Y,Wang SD,Hu H,Zhang YS,Qian LJ
Sat Feb 26 00:00:00 EST 2022
Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway.
Frontiers in pharmacology
Wang Y,Li Y,Wang L,Chen B,Zhu M,Ma C,Mu C,Tao A,Li S,Luo L,Ma P,Ji S,Lan T
Sat Jul 16 00:00:00 EDT 2022
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhan L,Pu J,Zheng J,Hang S,Pang L,Dai M,Ji C
Fri Apr 01 00:00:00 EDT 2022
METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.
Nature communications
Li Y,He X,Lu X,Gong Z,Li Q,Zhang L,Yang R,Wu C,Huang J,Ding J,He Y,Liu W,Chen C,Cao B,Zhou D,Shi Y,Chen J,Wang C,Zhang S,Zhang J,Ye J,You H
Wed Oct 26 00:00:00 EDT 2022
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Frontiers in cellular neuroscience
Liang W,Han B,Hai Y,Liu Y,Liu X,Yang J,Sun D,Yin P
Sat Jul 16 00:00:00 EDT 2022
Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells.
Animals : an open access journal from MDPI
Yi Y,Gao K,Lin P,Chen H,Zhou D,Tang K,Wang A,Jin Y
Mon Aug 29 00:00:00 EDT 2022
Hippocampal Mitochondrial Abnormalities Induced the Dendritic Complexity Reduction and Cognitive Decline in a Rat Model of Spinal Cord Injury.
Oxidative medicine and cellular longevity
Hu X,Wu L,Wen Y,Liu J,Li H,Zhang Y,Wang Z,Ding J,Zeng Z,Xia H
Thu May 19 00:00:00 EDT 2022
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Molecular neurodegeneration
Sudwarts A,Ramesha S,Gao T,Ponnusamy M,Wang S,Hansen M,Kozlova A,Bitarafan S,Kumar P,Beaulieu-Abdelahad D,Zhang X,Collier L,Szekeres C,Wood LB,Duan J,Thinakaran G,Rangaraju S
Sat May 07 00:00:00 EDT 2022
Developmental differences of in vitro cultured murine bone marrow- and fetal liver-derived megakaryocytes.
Platelets
Bertović I,Bura A,Jurak Begonja A
Thu Aug 18 00:00:00 EDT 2022
RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome.
Virulence
Zhang L,Lin J,Weng M,Wen Y,Zhang Y,Deng W
Thu Dec 01 00:00:00 EST 2022
The Antitumor Effect and Mechanism of Total Flavonoids From Coreopsis Tinctoria Nutt (Snow Chrysanthemum) on Lung Cancer Using Network Pharmacology and Molecular Docking.
Frontiers in pharmacology
Wufuer Y,Yang X,Guo L,Aximujiang K,Zhong L,Yunusi K,Wu G
Fri Apr 01 00:00:00 EDT 2022
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Journal of neuroinflammation
Kou L,Chi X,Sun Y,Han C,Wan F,Hu J,Yin S,Wu J,Li Y,Zhou Q,Zou W,Xiong N,Huang J,Xia Y,Wang T
Mon Jun 06 00:00:00 EDT 2022
Structure and transport mechanism of the human cholesterol transporter ABCG1.
Cell reports
Xu D,Li Y,Yang F,Sun CR,Pan J,Wang L,Chen ZP,Fang SC,Yao X,Hou WT,Zhou CZ,Chen Y
Tue Jan 25 00:00:00 EST 2022
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Experimental biology and medicine (Maywood, N.J.)
Jia Q,Yang R,Mehmood S,Li Y
Thu Sep 01 00:00:00 EDT 2022
Lithium attenuates blood-brain barrier damage and brain edema following intracerebral hemorrhage via an endothelial Wnt/β-catenin signaling-dependent mechanism in mice.
CNS neuroscience & therapeutics
Song D,Ji YB,Huang XW,Ma YZ,Fang C,Qiu LH,Tan XX,Chen YM,Wang SN,Chang J,Guo F
Wed Jun 01 00:00:00 EDT 2022
MiR-29b-1-5p regulates the proliferation and differentiation of chicken primary myoblasts and analysis of its effective targets.
Poultry science
Li Y,Zhai B,Yuan P,Fan S,Jin W,Li W,Sun G,Tian Y,Liu X,Kang X,Li G
Tue Feb 01 00:00:00 EST 2022
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Genes & nutrition
Peng M,Fan S,Li J,Zhou X,Liao Q,Tang F,Liu W
Mon Feb 14 00:00:00 EST 2022
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis.
Oncogene
Hua Z,Wei R,Guo M,Lin Z,Yu X,Li X,Gu C,Yang Y
Tue Mar 01 00:00:00 EST 2022
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.
Free radical biology & medicine
Shao C,Zhu J,Ma X,Siedlak SL,Cohen ML,Lerner A,Wang W
Tue Mar 01 00:00:00 EST 2022
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
Respiratory research
Zhan Y,Chen J,Wu J,Gu Y,Huang Q,Deng Z,Chen S,Wu X,Lv Y,Zeng Z,Xie J
Thu May 12 00:00:00 EDT 2022
SETD8 cooperates with MZF1 to participate in hyperglycemia-induced endothelial inflammation via elevation of WNT5A levels in diabetic nephropathy.
Cellular & molecular biology letters
Wang F,Hou W,Li X,Lu L,Huang T,Zhu M,Miao C
Sat Mar 26 00:00:00 EDT 2022
Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.
Frontiers in microbiology
Ruan Z,Liang Y,Chen Z,Yin J,Li C,Pan P,Zhang Q,Wu J,Luo Z
Tue Oct 25 00:00:00 EDT 2022
Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease.
Cardiovascular diabetology
You M,Liu Y,Wang B,Li L,Zhang H,He H,Zhou Q,Cao T,Wang L,Zhao Z,Zhu Z,Gao P,Yan Z
Tue Feb 15 00:00:00 EST 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.
Human molecular genetics
Kee TR,Wehinger JL,Gonzalez PE,Nguyen E,McGill Percy KC,Khan SA,Chaput D,Wang X,Liu T,Kang DE,Woo JA
Mon Nov 28 00:00:00 EST 2022
Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method.
Cellular and molecular life sciences : CMLS
Wang Y,Pandian N,Han JH,Sundaram B,Lee S,Karki R,Guy CS,Kanneganti TD
Wed Sep 28 00:00:00 EDT 2022
Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Communications biology
Baek Y,Woo TG,Ahn J,Lee D,Kwon Y,Park BJ,Ha NC
Wed Oct 12 00:00:00 EDT 2022
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis.
Cells
Qi H,Deng F,Wang Y,Zhang H,Kanwar YS,Dai Y
Wed Dec 21 00:00:00 EST 2022
SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells.
BMC biology
Yang Y,Qiu R,Zhao S,Shen L,Tang B,Weng Q,Xu Z,Zheng L,Chen W,Shu G,Wang Y,Zhao Z,Chen M,Ji J
Tue Dec 27 00:00:00 EST 2022
Epigenetic modifications inhibit the expression of MARVELD1 and in turn tumorigenesis by regulating the Wnt/β-catenin pathway in pan-cancer.
Journal of Cancer
Zhang J,Li Q,Sun Q,Wang B,Cui Y,Lou C,Yao Y,Zhang Y
Tue Jan 04 00:00:00 EST 2022
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1.
The FEBS journal
Chang YW,Song ZH,Chen CC
Fri Apr 01 00:00:00 EDT 2022
Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis.
Canadian journal of gastroenterology & hepatology
Peng H,Ye T,Deng L,Yang X,Jiang Z,Guo J
Thu Jan 12 00:00:00 EST 2023
Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.
International journal of biological sciences
Zhi S,Congcong Z,Zhiling G,Yihan Q,Yijing X,Guanjie L,Fang W,Xuehua S,Hongjie L,Xiaoni K,Yueqiu G
Thu Jun 02 00:00:00 EDT 2022
circSKIL promotes osteoblastic differentiation of periodontal ligament cells by sponging miR-532-5p to activate Notch signaling.
Journal of periodontal research
Zhong X,Wang H
Thu Dec 01 00:00:00 EST 2022
Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Luo J,Li L,Zhu Z,Chang B,Deng F,Wang D,Lu X,Zuo D,Chen Q,Zhou J
Sat Oct 01 00:00:00 EDT 2022
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Frontiers in pharmacology
Zhou J,Wang Y,Zhang L,Chen Q,Zhu X,Jiang P,Jiang N,Zhao W,Li B
Sat Jul 16 00:00:00 EDT 2022
Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon.
International journal of molecular sciences
Wang N,Li R,Feng B,Cheng Y,Guo Y,Qian H
Sat Feb 12 00:00:00 EST 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
GABA regulates IL-1β production in macrophages.
Cell reports
Fu J,Han Z,Wu Z,Xia Y,Yang G,Yin Y,Ren W
Tue Dec 06 00:00:00 EST 2022
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.
Nature communications
Xia J,Zhang J,Wu X,Du W,Zhu Y,Liu X,Liu Z,Meng B,Guo J,Yang Q,Wang Y,Wang Q,Feng X,Xie G,Shen Y,He Y,Xiang J,Wu M,An G,Qiu L,Jia W,Zhou W
Mon Jul 11 00:00:00 EDT 2022
R158Q and G212S, novel pathogenic compound heterozygous variants in SLC12A3 of Gitelman syndrome.
Frontiers of medicine
Li Z,Wu H,Wei S,Liu M,Shi Y,Li M,Wang N,Fang L,Xiang B,Gao L,Xu C,Zhao J
Thu Dec 01 00:00:00 EST 2022
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Journal of hazardous materials
Li S,Ma Y,Ye S,Hu D,Xiao F
Wed Jan 05 00:00:00 EST 2022
Early Aerobic Exercise Promotes Neurological Function Recovery of Rats after Cerebral Ischemia/Reperfusion by Upregulating the Expression of Heat Shock Protein A5.
Current medical science
Peng ZF,Zhang NB,Meng J,Zhang JH
Fri Apr 01 00:00:00 EDT 2022
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.
Pathology oncology research : POR
Chai Y,Jiao S,Peng X,Gan Q,Chen L,Hu X,Hao L,Zhang S,Tao Q
Tue Apr 05 00:00:00 EDT 2022
Melatonin Engineered Adipose-Derived Biomimetic Nanovesicles Regulate Mitochondrial Functions and Promote Myocardial Repair in Myocardial Infarction.
Frontiers in cardiovascular medicine
Zhang Y,Yang N,Huang X,Zhu Y,Gao S,Liu Z,Cao F,Wang Y
Wed Apr 13 00:00:00 EDT 2022
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16.
Cell death & disease
Zhao H,Zhao T,Yang J,Huang Q,Wu H,Pan Y,Wang H,Qian Y
Thu Jan 20 00:00:00 EST 2022
NF-κB-coupled IL17 mediates inflammatory signaling and intestinal inflammation in Artemia sinica.
Fish & shellfish immunology
Wang Z,Sun X,Wang W,Zheng M,Zhang D,Yin H
Thu Sep 01 00:00:00 EDT 2022
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
iScience
Zhou R,Tian K,Huang J,Duan W,Fu H,Feng Y,Wang H,Jiang Y,Li Y,Wang R,Hu J,Ma H,Qi Z,Ji X
Fri Sep 16 00:00:00 EDT 2022
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Frontiers in immunology
Shi B,Hao Y,Li W,Dong H,Xu M,Gao P
Thu May 19 00:00:00 EDT 2022
β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression.
Journal of neuroinflammation
Liu Y,Song N,Yao H,Jiang S,Wang Y,Zheng Y,Zhou Y,Ding J,Hu G,Lu M
Sat Oct 01 00:00:00 EDT 2022
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Cell death & disease
Lou Y,Tian X,Sun C,Song M,Han M,Zhao Y,Song Y,Song X,Zhang W,Chen YH,Wang H
Wed Apr 06 00:00:00 EDT 2022
Spindle pole body component 24 homolog potentiates tumor progression via regulation of SRY-box transcription factor 2 in clear cell renal cell carcinoma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sun C,Wei J,Long Z,Zhao W,Huangfu Q,Xie Q,Wang B,Wen J
Tue Feb 01 00:00:00 EST 2022
Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells.
BioMed research international
Zheng X,Wang P,Jia M,Li Q,Zhang A,Zhou Q
Fri Apr 08 00:00:00 EDT 2022
Enhanced Intracellular Reactive Oxygen Species by Photodynamic Therapy Effectively Promotes Chemoresistant Cell Death.
International journal of biological sciences
Xu X,Wang C,Zhang P,Gao X,Guan W,Wang F,Li X,Yuan J,Dou H,Xu G
Mon Mar 28 00:00:00 EDT 2022
BRAT1 links Integrator and defective RNA processing with neurodegeneration.
Nature communications
Cihlarova Z,Kubovciak J,Sobol M,Krejcikova K,Sachova J,Kolar M,Stanek D,Barinka C,Yoon G,Caldecott KW,Hanzlikova H
Fri Aug 26 00:00:00 EDT 2022
Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy.
Frontiers in pharmacology
Cao X,Liang Y,Liu R,Zao X,Zhang J,Chen G,Liu R,Chen H,He Y,Zhang J,Ye Y
Tue Mar 29 00:00:00 EDT 2022
TCQA, A Natural Caffeoylquinic Acid Derivative Attenuates H2O2-Induced Neuronal Apoptosis by Suppressing Phosphorylation of MAPKs Signaling Pathway.
Planta medica
Yang Y,Ding Y,Gao H,Jiang X,Zhao Q
Sat Oct 01 00:00:00 EDT 2022
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement.
Cell reports
Ruan GX,Li Y,Chen W,Huang H,Zhang R,Chen C,Lam KP,Xu S,Ou X
Tue Feb 08 00:00:00 EST 2022
MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang L,Wang L,Hu XB,Hou M,Xiao Y,Xiang JW,Xie J,Chen ZG,Yang TH,Nie Q,Fu JL,Wang Y,Zheng SY,Liu YF,Gan YW,Gao Q,Bai YY,Wang JM,Qi RL,Zou M,Ke Q,Zhu XF,Gong L,Liu Y,Li DW
Sun May 01 00:00:00 EDT 2022
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Journal of periodontal research
Shimizu Y,Takeda-Kawaguchi T,Kuroda I,Hotta Y,Kawasaki H,Hariyama T,Shibata T,Akao Y,Kunisada T,Tatsumi J,Tezuka KI
Sat Jan 01 00:00:00 EST 2022
Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.
Fitoterapia
Li C,Ru YJ,Lin QY,Gao GC,Yang YD,Zhang XQ,Gao JL,Liu SH,Zheng CW,Wang L,Zheng YX,Wu JM
Sat Oct 01 00:00:00 EDT 2022
Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR-144-3p/IGF2R axis.
Drug development research
Yuan D,Guo T,Qian H,Ge H,Zhao Y,Huang A,Wang X,Cao X,Zhu D,He C,Yu H
Thu Sep 01 00:00:00 EDT 2022
Guanxinning tablet inhibits the interaction between leukocyte integrin Mac-1 and platelet GPIbα for antithrombosis without increased bleeding risk.
Chinese journal of natural medicines
Yang QQ,Fang MS,Tu J,Ma QX,Shen LY,Xu YY,Chen J,Chen ML
Mon Aug 01 00:00:00 EDT 2022
Dopamine 1 receptors inhibit apoptosis via activating CSE/H2 S pathway in high glucose-induced vascular endothelial cells.
Cell biology international
Li H,Wu R,Xi Y,Li H,Chang G,Sun F,Wei C,Jiao L,Wen X,Zhang G,Zaid A,Hao J
Fri Jul 01 00:00:00 EDT 2022
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.
iScience
Chen X,Sheng L,Ma J,Qi D,Li X,Wang Z,Wu Z,Wong L,Huang JH,Wu E,Ma Q,Zhang D
Fri Jan 21 00:00:00 EST 2022
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Bioengineered
Yao D,Lin S,Chen S,Wang Z
Fri Apr 01 00:00:00 EDT 2022
Acadesine alleviates acute pancreatitis-related lung injury by mediating the barrier protective function of pulmonary microvascular endothelial cells.
International immunopharmacology
Zhu X,Duan F,Zhang Y,Wang X,Wang Y,Chen J,Zhang L,Wu M,Pan Z,Chen B
Sat Oct 01 00:00:00 EDT 2022
PM2.5 Synergizes With Pseudomonas aeruginosa to Suppress Alveolar Macrophage Function in Mice Through the mTOR Pathway.
Frontiers in pharmacology
Zhang J,Liu C,Zhao G,Li M,Ma D,Meng Q,Tang W,Huang Q,Shi P,Li Y,Jiang L,Yu X,Zhu H,Chen G,Zhang X
Sat Jul 16 00:00:00 EDT 2022
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Cellular & molecular biology letters
Liang Z,Liu L,Gao R,Che C,Yang G
Sun Oct 09 00:00:00 EDT 2022
MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma.
Iranian journal of basic medical sciences
Zhao C,Liu J,Xu Y,Guo J,Wang L,Chen L,Xu L,Dong G,Zheng W,Li Z,Cai H,Li S
Sat Oct 01 00:00:00 EDT 2022
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Molecular & cellular proteomics : MCP
Kaokhum N,Pinto-Fernández A,Wilkinson M,Kessler BM,Ismail HM
Thu Dec 01 00:00:00 EST 2022
Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.
International journal of molecular sciences
Simbulan-Rosenthal CM,Haribabu Y,Vakili S,Kuo LW,Clark H,Dougherty R,Alobaidi R,Carney B,Sykora P,Rosenthal DS
Sun Feb 20 00:00:00 EST 2022
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Pharmacological research
Shen Y,Yang R,Zhao J,Chen M,Chen S,Ji B,Chen H,Liu D,Li L,Du G
Tue Feb 01 00:00:00 EST 2022
Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin.
Pharmacological reports : PR
Chuang HW,Wei IH,Li CT,Huang CC
Fri Apr 01 00:00:00 EDT 2022
Elevation of N-acetyltransferase 10 in hippocampal neurons mediates depression- and anxiety-like behaviors.
Brain research bulletin
Guo XF,Wang XH,Fu YL,Meng Q,Huang BY,Yang R,Guo Y,Du YR,Wang X,Gao Y,Song L,Gong M,Wang S,Li YD,Shi HS,Shi Y
Fri Jul 01 00:00:00 EDT 2022
Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione.
Fish & shellfish immunology
Deng H,Li Y,Li J,Shen W,Chen Q,Weng S,He J,Xu X
Mon Aug 01 00:00:00 EDT 2022
KLF2 mediates the suppressive effect of BDNF on diabetic intimal calcification by inhibiting HK1 induced endothelial-to-mesenchymal transition.
Cellular signalling
Wang FF,Zhang JL,Ji Y,Yan XJ,Sun L,Zhu Y,Jin H
Wed Jun 01 00:00:00 EDT 2022
Tanshinone IIA inhibits cell growth by suppressing SIX1-induced aerobic glycolysis in non-small cell lung cancer cells.
Oncology letters
Qi H,Chen Z,Qin Y,Wang X,Zhang Z,Li Y
Wed Jun 01 00:00:00 EDT 2022
Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.
Viruses
Ma P,Gu K,Li H,Zhao Y,Li C,Wen R,Zhou C,Lei C,Yang X,Wang H
Sat May 14 00:00:00 EDT 2022
The Slack Channel Regulates Anxiety-Like Behaviors via Basolateral Amygdala Glutamatergic Projections to Ventral Hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhang Q,Gao SH,Shen ZS,Wang Y,Hu SW,Duan GB,Liu Y,Zhong DY,Liu J,Sun MH,Zhang X,Cao TY,Cao JL,Tang QY,Zhang Z
Wed Apr 06 00:00:00 EDT 2022
Anti-tumor activity of polysaccharides extracted from Pinus massoniana pollen in colorectal cancer- in vitro and in vivo studies.
Food & function
Shang H,Niu X,Cui W,Sha Z,Wang C,Huang T,Guo P,Wang X,Gao P,Zhang S,Wei K,Zhu R
Mon Jun 06 00:00:00 EDT 2022
Involvement of PI3K/Akt signaling pathway in promoting osteogenesis on titanium implant surfaces modified with novel non-thermal atmospheric plasma.
Frontiers in bioengineering and biotechnology
Zheng Z,He Y,Long L,Gan S,Chen S,Zhang M,Xu J,Fu R,Liao Y,Zhu Z,Wang H,Chen W
Tue Oct 04 00:00:00 EDT 2022
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
The Journal of nutritional biochemistry
Qi L,Jiang J,Yu G,Zhang X,Qi X,Zhang J,Zhang L,Wang T
Wed Jun 01 00:00:00 EDT 2022
β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway.
Gene
Nie Q,Peng WW,Wang Y,Zhong L,Zhang X,Zeng L
Fri Apr 15 00:00:00 EDT 2022
FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.
Cell death & disease
Cai K,Chen S,Zhu C,Li L,Yu C,He Z,Sun C
Sat Sep 03 00:00:00 EDT 2022
Gallic acid induces T-helper-1-like Treg cells and strengthens immune checkpoint blockade efficacy.
Journal for immunotherapy of cancer
Deng B,Yang B,Chen J,Wang S,Zhang W,Guo Y,Han Y,Li H,Dang Y,Yuan Y,Dai X,Zang Y,Li Y,Li B
Fri Jul 01 00:00:00 EDT 2022
Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.
Bulletin of experimental biology and medicine
Wu Q,Qu M,Zhong P,Zeng Y,Wang J,Zhang Q,Wang T,Liu D,Yang L,Zhou J,Wang T
Tue Feb 01 00:00:00 EST 2022
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Bioactive materials
Chen J,Zhu H,Zhu Y,Zhao C,Wang S,Zheng Y,Xie Z,Jin Y,Song H,Yang L,Zhang J,Dai J,Hu Z,Wang H
Tue Mar 01 00:00:00 EST 2022
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p.
Toxicology in vitro : an international journal published in association with BIBRA
Han W,Tao X,Weng T,Chen L
Tue Mar 01 00:00:00 EST 2022
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang Y,Yang Z,Gu J,Zhang Y,Wang X,Teng Z,Wang D,Gao L,Li W,Yeh S,Han Z
Tue Feb 01 00:00:00 EST 2022
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.
Molecular medicine (Cambridge, Mass.)
Zhou J,Lu Y,Jia Y,Lu J,Jiang Z,Chen K
Mon Jan 03 00:00:00 EST 2022
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Journal of inflammation research
Hao M,Ding C,Sun S,Peng X,Liu W
Wed Sep 07 00:00:00 EDT 2022
DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways.
Neuroscience
Wang T,Xue Y,Li Y,Gao S,Peng L,Zhao Y,Yu S
Thu Nov 10 00:00:00 EST 2022
Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis.
Frontiers in pharmacology
Chang Z,Zhang Y,Lin M,Wen S,Lai H,Zhan Y,Zhu X,Huang Z,Zhang X,Liu Z
Tue Oct 25 00:00:00 EDT 2022
High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.
Brain research bulletin
Yan J,Zhang F,Niu L,Wang X,Lu X,Ma C,Zhang C,Song J,Zhang Z
Wed Jun 01 00:00:00 EDT 2022
Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53.
Journal of Zhejiang University. Science. B
Li M,Su Y,Gao X,Yu J,Wang Z,Wang X
Tue Mar 15 00:00:00 EDT 2022
Vaccarin alleviates endothelial inflammatory injury in diabetes by mediating miR-570-3p/HDAC1 pathway.
Frontiers in pharmacology
Li T,Yu X,Zhu X,Wen Y,Zhu M,Cai W,Hou B,Xu F,Qiu L
Tue Sep 20 00:00:00 EDT 2022
The c.612A>G mutation of MC4R affects constitutive activity and signaling in domestic goats.
Animal genetics
Yan Y,Chi S,Liu G,Huang Y,Pan D,Jiang X
Sat Oct 01 00:00:00 EDT 2022
Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.
BMC pulmonary medicine
Tang Y,Tan S,Li M,Tang Y,Xu X,Zhang Q,Fu Q,Tang M,He J,Zhang Y,Zheng Z,Peng J,Zhu T,Xie W
Tue Apr 12 00:00:00 EDT 2022
Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism.
Frontiers in molecular neuroscience
Qi C,Chen A,Mao H,Hu E,Ge J,Ma G,Ren K,Xue Q,Wang W,Wu S
Fri Apr 29 00:00:00 EDT 2022
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao AN,Yang Z,Wang DD,Shi B,Zhang H,Bai Y,Yan BW,Zhang Y,Wen JK,Wang XL,Qu CB
Tue Nov 01 00:00:00 EDT 2022
Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats.
BMC musculoskeletal disorders
Wu Q,Zhong P,Ning P,Tan L,Huang X,Peng T,Yin L,Luo F,Qu M,Zhou J
Tue Dec 13 00:00:00 EST 2022
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Oxidative medicine and cellular longevity
Xu C,Ni S,Xu N,Yin G,Yu Y,Zhou B,Zhao G,Wang L,Zhu R,Jiang S,Wang Y
Mon Dec 12 00:00:00 EST 2022
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Physiological research
Sokouti H,Mohajeri D,Nourazar MA
Wed Aug 31 00:00:00 EDT 2022
Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer.
BMC cancer
Tang Y,Luo J,Zhou Y,Zang H,Yang Y,Liu S,Zheng H,Ma J,Fan S,Wen Q
Fri May 20 00:00:00 EDT 2022
Exploring the Effective Components and Mechanism of Action of Japanese Ardisia in the Treatment of Autoimmune Hepatitis Based on Network Pharmacology and Experimental Verification.
Pharmaceuticals (Basel, Switzerland)
Fu T,Chen Y,Li J,Zhu P,He H,Zhang W,Yung KKL,Wu W
Thu Nov 24 00:00:00 EST 2022
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.
Microbiology spectrum
Wang T,Liu B,Zhang C,Fang T,Ding Y,Song G,Zhang S,Shi L,Deng X,Wang J
Wed Aug 31 00:00:00 EDT 2022
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease.
Molecular and cellular neurosciences
Schneider JS,Singh G,Williams CK,Singh V
Sun May 01 00:00:00 EDT 2022
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fu Y,Yuan P,Zheng Y,Gao L,Wei Y,Chen Y,Li P,Ruan Y,Zheng X,Feng W
Wed Jun 01 00:00:00 EDT 2022
Extracellular Vesicles-Encapsulated miR-153-3p Potentiate the Survival and Invasion of Lung Adenocarcinoma.
Molecules and cells
Cao H,Zhang P,Yu H,Xi J
Thu Jun 30 00:00:00 EDT 2022
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
Metabolism: clinical and experimental
Luo Q,Liang W,Zhang Z,Zhu Z,Chen Z,Hu J,Yang K,Chi Q,Ding G
Thu Sep 01 00:00:00 EDT 2022
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Toxins
Shi J,Wang Y,Xu W,Cai G,Zou H,Yuan Y,Gu J,Liu Z,Bian J
Wed May 25 00:00:00 EDT 2022
Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells.
Molecules (Basel, Switzerland)
Wang M,Xiang Y,Wang R,Zhang L,Zhang H,Chen H,Luan X,Chen L
Fri Nov 11 00:00:00 EST 2022
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.
EMBO reports
Wang D,Xiu J,Zhao J,Luo J
Tue Apr 05 00:00:00 EDT 2022
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
Molecular cell
Zhou Q,Hao B,Cao X,Gao L,Yu Z,Zhao Y,Zhu M,Zhong G,Chi F,Dai X,Mao J,Zhu Y,Rong P,Chen L,Bai X,Ye C,Chen S,Liang T,Li L,Feng XH,Tan M,Zhao B
Thu Dec 15 00:00:00 EST 2022
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Redox biology
Zhang Y,Li Y,Zhou L,Yuan X,Wang Y,Deng Q,Deng Z,Xu S,Wang Q,Xie H,Li J
Thu Sep 01 00:00:00 EDT 2022
High expression of HOXA4 in patients with glioma indicates unfavorable clinical outcomes.
Cell cycle (Georgetown, Tex.)
Yu Z,Liu Z,Lian X,Cheng X,Liu B,Zhang B,Wang H,Wang J,Li A,Ren Z,Pang B,Qian R,Gao Y
Tue Nov 01 00:00:00 EDT 2022
A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection.
Biomaterials research
Liu J,Zhu H,Pei Y,Zhang H,Zhou J,Jing Z
Mon Apr 25 00:00:00 EDT 2022
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Cell communication and signaling : CCS
Zhou F,Liu Y,Ai W,Wang Y,Gan M,Jiang Q,Han T,Wang JB
Tue Aug 30 00:00:00 EDT 2022
In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration.
Platelets
Widyaningrum R,Wu YW,Delila L,Lee DY,Wang TJ,Burnouf T
Thu Nov 17 00:00:00 EST 2022
Co-delivery of EGCG and lycopene via a pickering double emulsion induced synergistic hypolipidemic effect.
Food & function
Wang Q,Wang L,Tian W,Song M,Cao Y,Xiao J
Mon Mar 21 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Pharmaceutical biology
Yang Y,Ren ZZ,Wei WJ,He ZL,Deng YL,Wang Z,Fan YC,Zhou J,Jiang LH
Thu Dec 01 00:00:00 EST 2022
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration.
Journal of physiology and biochemistry
Ding R,Li G,Yao Y,Zhang L,Zhang X,Li J,Shen T,Gao Y,Wu T,Kong S,Huang M,Li Y
Tue Feb 01 00:00:00 EST 2022
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Biochimica et biophysica acta. Molecular cell research
Wang J,Ouyang X,Zhou Z,Mao S,Niu X,Li H,Xu W,Song Y,Cao J,Lai B
Sat Jan 01 00:00:00 EST 2022
Advanced glycation end products induce Aβ1-42 deposition and cognitive decline through H19/miR-15b/BACE1 axis in diabetic encephalopathy.
Brain research bulletin
Jiang L,Yuan N,Zhao N,Tian P,Zhang D,Qin Y,Shi Z,Gao Z,Zhang N,Zhou H,Zhang R,Xu S
Sat Oct 01 00:00:00 EDT 2022
Immunoproteasome modulates NLRP3 inflammasome-mediated neuroinflammation under cerebral ischaemia and reperfusion conditions.
Journal of cellular and molecular medicine
Chen X,Wang Y,Yao N,Lin Z
Sat Jan 01 00:00:00 EST 2022
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Ma M,Fan AY,Liu Z,Yang LQ,Huang JM,Pang ZY,Yin F
Sat Jul 16 00:00:00 EDT 2022
Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF.
BioMed research international
Liu Z,Xu Z,Wang X,Zhang Y,Wu Y,Jiang D,Jia R
Tue Dec 06 00:00:00 EST 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Biochemical and biophysical research communications
Wang KX,Yan C,Yang X,Zhu PY,Cui WW,Ye C,Hu K,Lan T,Huang LY,Wang W,Ma P,Qi SH,Gu B,Luo L
Sat Jun 18 00:00:00 EDT 2022
Effects of Pereskia aculeate Miller Petroleum Ether Extract on Complete Freund's Adjuvant-Induced Rheumatoid Arthritis in Rats and its Potential Molecular Mechanisms.
Frontiers in pharmacology
Chen Y,Liu K,Qin Y,Chen S,Guan G,Huang Y,Chen Y,Mo Z
Sat Jul 16 00:00:00 EDT 2022
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
World journal of gastroenterology
Zhang JJ,Cao CX,Wan LL,Zhang W,Liu ZJ,Wang JL,Guo Q,Tang H
Sat May 07 00:00:00 EDT 2022
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Journal of virology
Shi J,Li Z,Xu R,Zhang J,Zhou Q,Gao R,Lu H,Lan Y,Zhao K,He H,Gao F,He W
Wed Jan 12 00:00:00 EST 2022
Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.
Cell reports
Chen W,Li Y,Ruan GX,Huang H,Zhang R,Wang J,Ouyang Y,Li Y,Xu S,Ou X
Tue Nov 22 00:00:00 EST 2022
RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions.
Molecular cancer research : MCR
Cho JH,Park S,Kim S,Kang SM,Woo TG,Yoon MH,Lee H,Jeong M,Park YH,Kim H,Han YT,Suh YG,Kim BH,Kwon Y,Yun H,Park BJ
Tue Mar 01 00:00:00 EST 2022
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
American journal of cancer research
Lin H,Gao Y,Sun K,Zhang Q,Li Y,Chen M,Jin F
Tue Sep 20 00:00:00 EDT 2022
Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang L,Zhao Q,Cang H,Wang Z,Hu X,Pan R,Yang Y,Chen Y
Wed Jun 01 00:00:00 EDT 2022
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Journal of oncology
Ma L,Shen T,Peng H,Wu J,Wang W,Gao X
Mon May 02 00:00:00 EDT 2022
Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors.
Cancers
Verdura S,Encinar JA,Teixidor E,Segura-Carretero A,Micol V,Cuyàs E,Bosch-Barrera J,Menendez JA
Sun Dec 11 00:00:00 EST 2022
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Free radical biology & medicine
Li Y,Jiang Y,Zhou W,Wu Y,Zhang S,Ding G,Zhang Y,Zhang A,Huang S,Jia Z,You R
Tue Mar 01 00:00:00 EST 2022
CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.
EMBO reports
Hu WT,Liuyang ZY,Tian Y,Liang JW,Zhang XL,Zhang HL,Wang G,Huo Y,Shentu YP,Wang JZ,Wang XC,Lu YM,Westermarck J,Man HY,Liu R
Tue Dec 06 00:00:00 EST 2022
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Stem cell research & therapy
Zhou J,Yang J,Dong Y,Shi Y,Zhu E,Yuan H,Li X,Wang B
Tue Jun 28 00:00:00 EDT 2022
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Dong S,Liang S,Cheng Z,Zhang X,Luo L,Li L,Zhang W,Li S,Xu Q,Zhong M,Zhu J,Zhang G,Hu S
Sat Jan 08 00:00:00 EST 2022
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Phytotherapy research : PTR
Wang L,Cheng L,Ma L,Ahmad Farooqi A,Qiao G,Zhang Y,Ye H,Liu M,Huang J,Yang X,Lin X,Cao S
Sat Jan 01 00:00:00 EST 2022
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Biochimica et biophysica acta. Molecular cell research
Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L
Tue Feb 01 00:00:00 EST 2022
Extracellular HSP90α promotes cellular senescence by modulating TGF-β signaling in pulmonary fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhong W,Chen W,Liu Y,Zhang J,Lu Y,Wan X,Qiao Y,Huang H,Zeng Z,Li W,Meng X,Zhao H,Zou M,Cai S,Dong H
Mon Aug 01 00:00:00 EDT 2022
Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathway.
Pharmaceutical biology
Huang X,Yu H,Xie C,Zhou YL,Chen MM,Shi HL,Tang WF,Dong JC,Luo QL
Thu Dec 01 00:00:00 EST 2022
Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages.
Journal of inflammation research
Peng K,Deng N,Meng Y,He Q,Meng H,Luo T,Wei Y,Kang Y,Zhou X,Shen F
Tue Sep 06 00:00:00 EDT 2022
PRSS2 overexpression relates to poor prognosis and promotes proliferation, migration and invasion in gastric cancer.
Tissue & cell
Chen Y,Wang B,Zhao Z,Li M,Wang F
Thu Dec 01 00:00:00 EST 2022
β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.
Cell reports
Zheng Y,Sun W,Shan C,Li B,Liu J,Xing H,Xu Q,Cui B,Zhu W,Chen J,Liu L,Yang T,Sun N,Li X
Tue Dec 20 00:00:00 EST 2022
Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.
NPJ science of food
Harada N,Okuyama M,Teraoka Y,Arahori Y,Shinmori Y,Horiuchi H,Luis PB,Joseph AI,Kitakaze T,Matsumura S,Hira T,Yamamoto N,Iuni T,Goshima N,Schneider C,Inui H,Yamaji R
Fri Jan 14 00:00:00 EST 2022
Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.
Stem cell research & therapy
Yi Y,Wu M,Zhou X,Xiong M,Tan Y,Yu H,Liu Z,Wu Y,Zhang Q
Mon Mar 21 00:00:00 EDT 2022
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Biological trace element research
Xiong Y,Li J,He S
Tue Feb 01 00:00:00 EST 2022
Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB).
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xiao F,Deng J,Jiao F,Hu X,Jiang H,Yuan F,Chen S,Niu Y,Jiang X,Guo F
Sat Oct 01 00:00:00 EDT 2022
Gandouling Mitigates CuSO4-Induced Heart Injury in Rats.
Animals : an open access journal from MDPI
Fang S,Yang W,Zhang K,Peng C
Sat Oct 08 00:00:00 EDT 2022
Porphyromonas gingivalis lipopolysaccharide affects the angiogenic function of endothelial progenitor cells via Akt/FoxO1 signaling.
Journal of periodontal research
Deng H,Gong Y,Chen Y,Zhang G,Chen H,Cheng T,Jin L,Wang Y
Mon Aug 01 00:00:00 EDT 2022
7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis.
Biochemical and biophysical research communications
Zhang W,Xue H,Zhou C,Zheng Z,Xing M,Chu H,Li P,Zhang N,Dang Y,Xu X
Sat Sep 24 00:00:00 EDT 2022
miR-199-5p regulates spermiogenesis at the posttranscriptional level via targeting Tekt1 in allotriploid crucian carp.
Journal of animal science and biotechnology
Li S,Wang Q,Huang L,Fan S,Li T,Shu Y,Zhang C,Zhou Y,Liu Q,Luo K,Tao M,Liu S
Wed Apr 13 00:00:00 EDT 2022
Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung.
Frontiers in immunology
Miura Y,Ohkubo H,Nakano A,Bourke JE,Kanazawa S
Tue Nov 22 00:00:00 EST 2022
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
European journal of medicinal chemistry
Luo D,Guo Z,Zhao X,Wu L,Liu X,Zhang Y,Zhang Y,Deng Z,Qu X,Cui S,Wan S
Wed Jan 05 00:00:00 EST 2022
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis.
Cell discovery
Kuang W,Jin H,Yang F,Chen X,Liu J,Li T,Chang Y,Liu M,Xu Z,Huo C,Yan X,Yang Y,Liu W,Shu Q,Xie S,Zhou T
Fri Mar 11 00:00:00 EST 2022
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
Viruses
Zhao N,Wang F,Kong Z,Shang Y
Sat Jul 02 00:00:00 EDT 2022
Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine.
Immunity
Xiong Z,Zhu X,Geng J,Xu Y,Wu R,Li C,Fan D,Qin X,Du Y,Tian Y,Fan Z
Tue Apr 12 00:00:00 EDT 2022
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Frontiers in oncology
Wang Y,He H,Chen J,Song Z,Pan X,Lan T,Wang G
Tue Aug 02 00:00:00 EDT 2022
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
International immunopharmacology
Liang S,Zhou Z,Zhou Z,Liang J,Lin W,Zhang C,Zhou C,Zhao H,Meng X,Zou F,Yu C,Cai S
Thu Dec 01 00:00:00 EST 2022
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
International journal of molecular sciences
Lan T,Zhang K,Lin F,He Q,Wu S,Xu Z,Zhang Y,Quan F
Wed Aug 03 00:00:00 EDT 2022
Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts.
Veterinary research
Pan Y,Cai W,Cheng A,Wang M,Chen S,Huang J,Yang Q,Wu Y,Sun D,Mao S,Zhu D,Liu M,Zhao X,Zhang S,Gao Q,Ou X,Tian B,Yin Z,Jia R
Thu Jul 07 00:00:00 EDT 2022
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Transplantation
Wang Z,Liu D,Yan Q,Liu F,Zhan M,Qi S,Fang Q,Yao L,Wang W,Zhang R,Du J,Chen L
Fri Jul 01 00:00:00 EDT 2022
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
International journal of biological sciences
Chen K,Wang Q,Liu X,Wang F,Yang Y,Tian X
Fri Apr 15 00:00:00 EDT 2022
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice.
European journal of histochemistry : EJH
Yan F,Zhu H,He Y,Wu Q,Duan X
Fri Nov 11 00:00:00 EST 2022
Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.
Phytotherapy research : PTR
Yan K,Hu J,Hou T,Ci X,Peng L
Sun May 01 00:00:00 EDT 2022
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
American journal of translational research
Yu X,Kang W,Zhang J,Chen C,Liu Y
Wed Oct 19 00:00:00 EDT 2022
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
American journal of translational research
Yu X,Kang W,Zhang J,Chen C,Liu Y
Wed Oct 19 00:00:00 EDT 2022
Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine.
Molecules (Basel, Switzerland)
Zhao J,Zhao Z,Hou W,Jiang Y,Liu G,Ren X,Liu K,Liu H,Chen K,Huang H
Sun Aug 14 00:00:00 EDT 2022
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Current protocols
Bryant JD,Lei Y,VanPortfliet JJ,Winters AD,West AP
Tue Feb 01 00:00:00 EST 2022
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics.
Frontiers in immunology
Lv L,Zhang T,Jia H,Zhang Y,Ahsan A,Zhao X,Chen T,Shen Z,Shen N
Fri Dec 23 00:00:00 EST 2022
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
International journal of molecular sciences
Liu X,Shi Q,Choudhry N,Zhang T,Liu H,Zhang S,Zhang J,Yang D
Tue Oct 11 00:00:00 EDT 2022
Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.
Frontiers in pharmacology
Tan Z,Si Y,Yu Y,Ding J,Huang L,Xu Y,Zhang H,Lu Y,Wang C,Yu B,Yuan L
Sat Jul 16 00:00:00 EDT 2022
Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
Frontiers in cell and developmental biology
Li J,Dang X,Franco A,Dorn GW
Wed Sep 21 00:00:00 EDT 2022
Anti-inflammatory, antioxidant and anti-virulence roles of atractylodin in attenuating Listeria monocytogenes infection.
Frontiers in immunology
Xu L,Zhou Y,Xu J,Xu X,Lu G,Lv Q,Wei L,Deng X,Shen X,Feng H,Wang J
Mon Nov 21 00:00:00 EST 2022
High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth.
BMC medicine
Wang Z,Wang M,Zhang M,Xu K,Zhang X,Xie Y,Zhang Y,Chang C,Li X,Sun A,He F
Tue Aug 09 00:00:00 EDT 2022
Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1-FGL1-MYH9 axis.
Frontiers in immunology
Tang XY,Xiong YL,Zhao YB,Yang J,Shi AP,Zheng KF,Liu YJ,Shu C,Jiang T,Ma N,Zhao JB
Mon Oct 24 00:00:00 EDT 2022
3D-Printed β-Tricalcium Phosphate Scaffolds Promote Osteogenic Differentiation of Bone Marrow-Deprived Mesenchymal Stem Cells in an N6-methyladenosine-Dependent Manner.
International journal of bioprinting
Jiao X,Sun X,Li W,Chu W,Zhang Y,Li Y,Wang Z,Zhou X,Ma J,Xu C,Dai K,Wang J,Gan Y
Sat Jul 16 00:00:00 EDT 2022
GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.
The Journal of biological chemistry
Ahat E,Bui S,Zhang J,da Veiga Leprevost F,Sharkey L,Reid W,Nesvizhskii AI,Paulson HL,Wang Y
Mon Aug 01 00:00:00 EDT 2022
Interferon-Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection.
Viruses
Pang Z,Hao P,Qu Q,Li L,Jiang Y,Xiao S,Jin N,Li C
Sun Oct 30 00:00:00 EDT 2022
Stearic Acid Activates the PI3K-mTOR-4EBP1/S6K and mTOR-SREBP-1 Signaling Axes through FATP4-CDK1 To Promote Milk Synthesis in Primary Bovine Mammary Epithelial Cells.
Journal of agricultural and food chemistry
Li F,Hu G,Long X,Cao Y,Li Q,Guo W,Wang J,Liu J,Fu S
Wed Apr 06 00:00:00 EDT 2022
Identification of ferroptosis-related genes for the prediction of prognosis and chemotherapy benefit of gastric cancer.
European review for medical and pharmacological sciences
Zheng JJ,Wang JP
Thu Sep 01 00:00:00 EDT 2022
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Journal of Zhejiang University. Science. B
Lu J,Fu S,Dai J,Hu J,Li S,Ji H,Wang Z,Yu J,Bao J,Xu B,Guo J,Yang H
Wed Jun 15 00:00:00 EDT 2022
Sleeve gastrectomy attenuated diabetes-related cognitive decline in diabetic rats.
Frontiers in endocrinology
Ding H,Liu C,Zhang S,Li B,Xu Q,Shi B,Li S,Dong S,Ma X,Zhang Y,Zhong M,Zhang G
Tue Nov 22 00:00:00 EST 2022
Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Gastrodia elata Blume in the treatment of ischemic stroke.
Experimental and therapeutic medicine
Luo Y,Chen P,Yang L,Duan X
Thu Dec 01 00:00:00 EST 2022
Astragalus polysaccharide alleviated the inhibition of CSFV C-strain replication caused by PRRSV via the TLRs/NF‑κB/TNF-α pathways.
Virus research
Chen D,Kang H,Tuo T,Wang L,Xia Y,Zhang Y,Zhou L,Ge X,Han J,Guo X,Yang H
Sun Oct 02 00:00:00 EDT 2022
Entacapone alleviates acute kidney injury by inhibiting ferroptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang J,Sun X,Huang N,Li P,He J,Jiang L,Zhang X,Han S,Xin H
Fri Jul 01 00:00:00 EDT 2022
Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway.
Oncogenesis
Lu L,Zha Z,Zhang P,Wang P,Liu X,Fang X,Weng C,Li B,Mao H,Wang L,Guan M,Wu Y,Xu Z,Liu Z,Liu G
Fri Apr 29 00:00:00 EDT 2022
Folic Acid-Modified Fluorescent-Magnetic Nanoparticles for Efficient Isolation and Identification of Circulating Tumor Cells in Ovarian Cancer.
Biosensors
Pan Y,Wang Z,Ma J,Zhou T,Wu Z,Ding P,Sun N,Liu L,Pei R,Zhu W
Mon Mar 21 00:00:00 EDT 2022
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Brain research
Zhang N,Shentu Y,Zhu M,Wang H,Yin X,Du C,Xue F,Fan J,Gong Y,Fan X
Thu Dec 15 00:00:00 EST 2022
Tea Tree Oil Mediates Antioxidant Factors Relish and Nrf2-Autophagy Axis Regulating the Lipid Metabolism of Macrobrachium rosenbergii.
Antioxidants (Basel, Switzerland)
Liu M,Zheng X,Sun C,Zhou Q,Liu B,Xu P
Wed Nov 16 00:00:00 EST 2022
AKAP9 Upregulation Predicts Unfavorable Prognosis in Pediatric Acute Myeloid Leukemia and Promotes Stemness Properties via the Wnt/β-Catenin Pathway.
Cancer management and research
Wu S,Shen D,Zhao L
Sat Apr 30 00:00:00 EDT 2022
Schisandra chinensis (Turcz.) Baill. Protects against DSS-induced colitis in mice: Involvement of TLR4/NF-κB/NLRP3 inflammasome pathway and gut microbiota.
Journal of ethnopharmacology
Bian Z,Qin Y,Li L,Su L,Fei C,Li Y,Hu M,Chen X,Zhang W,Mao C,Yuan X,Lu T,Ji D
Tue Nov 15 00:00:00 EST 2022
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Cell death discovery
Song L,Zhang L,Zhou Y,Shao X,Xu Y,Pei D,Wang Q
Thu Apr 21 00:00:00 EDT 2022
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis: An in vitro and in vivo experiment.
Journal of ethnopharmacology
Shi Q,Huang L,Duan J,Kuang G,Lu M,Tan X
Wed Aug 10 00:00:00 EDT 2022
Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection.
Viruses
Ma X,Li C,Xia Q,Zhang Y,Yang Y,Wahaab A,Liu K,Li Z,Li B,Qiu Y,Wei J,Ma Z
Tue Mar 29 00:00:00 EDT 2022
Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells.
Lipids
Kuwabara N,Ohta-Shimizu M,Fuwa F,Tomitsuka E,Sato S,Nakagawa S
Tue Nov 01 00:00:00 EDT 2022
METTL3-mediated m6A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy.
Molecular therapy : the journal of the American Society of Gene Therapy
Jiang L,Liu X,Hu X,Gao L,Zeng H,Wang X,Huang Y,Zhu W,Wang J,Wen J,Meng X,Wu Y
Wed Apr 06 00:00:00 EDT 2022
CAPRIN2 upregulation by LINC00941 promotes nasopharyngeal carcinoma ferroptosis resistance and metastatic colonization through HMGCR.
Frontiers in oncology
Qiu L,Zhou R,Zhou L,Yang S,Wu J
Tue Oct 25 00:00:00 EDT 2022
Skin epithelial cells change their mechanics and proliferation upon snail-mediated EMT signalling.
Soft matter
Hosseini K,Trus P,Frenzel A,Werner C,Fischer-Friedrich E
Wed Mar 30 00:00:00 EDT 2022
SIRT4 Expression Ameliorates the Detrimental Effect of Heat Stress via AMPK/mTOR Signaling Pathway in BMECs.
International journal of molecular sciences
Ding Q,Wang Y,Xia SW,Zhao F,Zhong JF,Wang HL,Chen KL
Tue Nov 01 00:00:00 EDT 2022
Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.
Journal of applied toxicology : JAT
Wang Y,Liu YP,Sun ZB,Deng WH,Yuan XY,Lei YD,Cai Y,Huang L,Zhang ZH
Thu Sep 01 00:00:00 EDT 2022
Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis.
International journal of biological sciences
Li H,Wang X,Mu H,Mei Q,Liu Y,Min Z,Zhang L,Su P,Xiang W
Fri Apr 15 00:00:00 EDT 2022
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Neurobiology of disease
Shen SY,Yu R,Li W,Liang LF,Han QQ,Huang HJ,Li B,Xu SF,Wu GC,Zhang YQ,Yu J
Fri Jul 01 00:00:00 EDT 2022
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Cancer cell international
Li W,Huang BS,Xiong YY,Yang LJ,Wu LX
Tue Jan 18 00:00:00 EST 2022
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Journal of cellular and molecular medicine
Zhou Y,Liu Y,Xu G,Liu L,Li H,Li Y,Yin J,Wang X,Yu Z
Mon Aug 01 00:00:00 EDT 2022
Natural Compound Library Screening Identifies Oroxin A for the Treatment of Myocardial Ischemia/Reperfusion Injury.
Frontiers in pharmacology
Cheng X,Huang T,Wang C,Hao S,Shu L,Wang S,Cheng G,Zhang Q,Huang J,Chen C
Sat Jul 16 00:00:00 EDT 2022
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Bioengineered
Wang C,Tang Z,Zhang Z,Liu T,Zhang J,Huang H,Li Y
Tue Mar 01 00:00:00 EST 2022
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
The Journal of biological chemistry
Wang J,Dong Y,Ma H,Wu L,Zhen X,Tang L,Jin J,Han S,Zhang P,Peng J
Sat Jan 01 00:00:00 EST 2022
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling.
European journal of pharmacology
Xiao X,Zhang Y,Tian S,Wang X,Zhang Q,Zhang L,Yu X,Ma C,Zheng X,Li Y,Zhang J,Qu L
Thu Sep 15 00:00:00 EDT 2022
miR-520d-3p/MIG-7 axis regulates vasculogenic mimicry formation and metastasis in osteosarcoma.
Neoplasma
Yao N,Zhou J,Song J,Jiang Y,Zhang J
Fri Jul 01 00:00:00 EDT 2022
TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.
Eye and vision (London, England)
Shen H,Gong Q,Zhang J,Wang H,Qiu Q,Zhang J,Luo D
Mon Sep 05 00:00:00 EDT 2022
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis.
Journal of molecular medicine (Berlin, Germany)
Zhao X,Zhao D,Geng B,Yaobin W,Xia Y
Tue Nov 01 00:00:00 EDT 2022
The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.
Oncogenesis
Ma X,Ma X,Zhu L,Zhao Y,Chen M,Li T,Lin Y,Ma D,Sun C,Han L
Wed Jul 20 00:00:00 EDT 2022
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Cell death & disease
Yi L,Hu Y,Wu Z,Li Y,Kong M,Kang Z,Zuoyuan B,Yang Z
Mon Jul 11 00:00:00 EDT 2022
Identification of FEZ2 as a potential oncogene in pancreatic ductal adenocarcinoma.
PeerJ
Yang C,Wang X,Qiu C,Zheng Z,Lin K,Tu M,Zhang K,Jiang K,Gao W
Tue Jul 18 00:00:00 EDT 2023
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
Evidence-based complementary and alternative medicine : eCAM
Ding P,Guo Y,Wang C,Chen J,Guo C,Liu H,Shi Q
Sat Jul 16 00:00:00 EDT 2022
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway.
JCI insight
Feng X,Xiao Y,He J,Yang M,Guo Q,Su T,Huang Y,Yi J,Li CJ,Luo XH,Liu XW,Zhou HY
Tue Mar 22 00:00:00 EDT 2022
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
Cell death & disease
Zhang W,Gong M,Zhang W,Mo J,Zhang S,Zhu Z,Wang X,Zhang B,Qian W,Wu Z,Ma Q,Wang Z
Wed Jul 20 00:00:00 EDT 2022
Vitamin D3 Suppresses Human Cytomegalovirus-Induced Vascular Endothelial Apoptosis via Rectification of Paradoxical m6A Modification of Mitochondrial Calcium Uniporter mRNA, Which Is Regulated by METTL3 and YTHDF3.
Frontiers in microbiology
Zhu W,Zhang H,Wang S
Sat Apr 02 00:00:00 EDT 2022
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao J,Chen J,Zhu W,Qi XM,Wu YG
Thu Sep 01 00:00:00 EDT 2022
Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.
Pharmacological research
Xie Y,Hu X,Li S,Qiu Y,Cao R,Xu C,Lu C,Wang Z,Yang J
Fri Apr 01 00:00:00 EDT 2022
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Evidence-based complementary and alternative medicine : eCAM
Zhan L,Liu H,Zheng J,Meng J,Fu D,Pang L,Ji C
Sat Jul 16 00:00:00 EDT 2022
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Cells
Fu HY,Xu JM,Ai X,Dang FT,Tan X,Yu HY,Feng J,Yang WX,Ma HT,Tu RF,Gupta AK,Manandhar LK,Bao WM,Tang YM
Sat Nov 26 00:00:00 EST 2022
Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway.
Frontiers in pharmacology
Liu F,Liu Y,Peng Q,Wang G,Tan Q,Ou Z,Xu Q,Liu C,Zuo D,Zhao J
Tue Sep 13 00:00:00 EDT 2022
Cellular protein HSC70 promotes fowl adenovirus serotype 4 replication in LMH cells via interacting with viral 100K protein.
Poultry science
Gao S,Chen H,Zhang X,Zhao J,Wang Z
Fri Jul 01 00:00:00 EDT 2022
Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Tsukahara T
Thu Sep 01 00:00:00 EDT 2022
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
European journal of pharmacology
Shi Y,Zhao L,Wang J,Liu S,Zhang Y,Qin Q
Thu Dec 15 00:00:00 EST 2022
The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang N,Tang S,Zhang J,Pei B,Pang T,Sun G
Tue Nov 01 00:00:00 EDT 2022
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
EMBO reports
Song P,Yang W,Lou KF,Dong H,Zhang H,Wang B,Chen D
Mon Nov 07 00:00:00 EST 2022
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis.
Cellular immunology
Fang H,Huang Y,Luo Y,Tang J,Yu M,Zhang Y,Zhong M
Sat Jan 01 00:00:00 EST 2022
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Journal of ethnopharmacology
Shen Y,Yang F,Peng H,Zhang G,Zhu F,Xu H,Shi L
Mon Jan 10 00:00:00 EST 2022
Prognostic and therapeutic implication of m6A methylation in Crohn disease.
Medicine
He Y,Hu Y,Yuan M,Xu W,Du Y,Liu J
Fri Dec 23 00:00:00 EST 2022
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Bioengineered
Liu W,Feng Y,Wang X,Ding J,Li H,Guan H,Chen Z
Fri Apr 01 00:00:00 EDT 2022
Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer.
Cancer management and research
Li S,Feng J,Weng H,Zhao F,Cui G,Fu W,Lin X,Hu H
Fri Sep 30 00:00:00 EDT 2022
AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity.
Molecules (Basel, Switzerland)
Hung CY,Chang CH,Lin TJ,Yi HH,Tsai NZ,Chen YR,Chen YT
Fri Feb 04 00:00:00 EST 2022
Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Frontiers in oncology
Zuo S,Wang H,Li L,Pan H,Lu L
Tue Mar 22 00:00:00 EDT 2022
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Xie M,Mak JWY,Yu H,Cheng CTY,Chan HCH,Chan TT,Lau LHS,Wong MTL,Ko WH,Jiang L,Yao X
Mon Jul 25 00:00:00 EDT 2022
PINK1/Parkin-Mediated Mitophagy Partially Protects against Inorganic Arsenic-Induced Hepatic Macrophage Polarization in Acute Arsenic-Exposed Mice.
Molecules (Basel, Switzerland)
Qu G,Liu Z,Zhang J,Guo Y,Li H,Qu R,Su W,Zhang H,Zhang L,Xu H,Shen F,Jiang S,Liu H,Li J
Tue Dec 13 00:00:00 EST 2022
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
Cancers
Zhang M,Shi Z,Zhang S,Li X,To SKY,Peng Y,Liu J,Chen S,Hu H,Wong AST,Zeng JZ
Tue Dec 20 00:00:00 EST 2022
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Journal of ethnopharmacology
Zhao CZ,Jiang W,Zhu YY,Wang CZ,Zhong WH,Wu G,Chen J,Zhu MN,Wu QL,Du XL,Luo YY,Li M,Wang HL,Zhao H,Ma QG,Zhong GY,Wei RR
Fri Mar 25 00:00:00 EDT 2022
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
International immunopharmacology
Li Y,Mao M,Zhu L,Sun Q,Tong J,Zhou Z
Fri Jul 01 00:00:00 EDT 2022
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yang D,Wu X,Wang W,Zhou Y,Wang Z
Sat Jan 01 00:00:00 EST 2022
MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1.
Frontiers in cellular neuroscience
Zhang YF,Li XX,Cao XL,Ji CC,Gao XY,Gao D,Han H,Yu F,Zheng MH
Sat Jul 16 00:00:00 EDT 2022
The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice.
iScience
Wu X,Yang D,Zhou Y,Li S,Wang Z
Fri Jul 15 00:00:00 EDT 2022
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Development (Cambridge, England)
Kong X,Shu X,Wang J,Liu D,Ni Y,Zhao W,Wang L,Gao Z,Chen J,Yang B,Guo X,Wang Z
Thu Dec 15 00:00:00 EST 2022
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Cell death & disease
Li Q,Chu Y,Li S,Yu L,Deng H,Liao C,Liao X,Yang C,Qi M,Cheng J,Chen G,Huang L
Wed Oct 26 00:00:00 EDT 2022
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma.
Heliyon
Peng H,Hou M,Wu Z,Wang J,Zhou M,Zhuang X,Xing J,Tao Q,Huang L,Zhou F,Zhang S,Feng Q,Hou Y,Yu Q
Tue Nov 01 00:00:00 EDT 2022
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Frontiers in oncology
Yuan H,Chen B,Chai R,Gong W,Wan Z,Zheng B,Hu X,Guo Y,Gao S,Dai Q,Yu P,Tu S
Tue Oct 25 00:00:00 EDT 2022
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Materials today. Bio
Wang L,Zhang D,Ren Y,Guo S,Li J,Ma S,Yao M,Guan F
Sat Jan 01 00:00:00 EST 2022
Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish.
Frontiers in pharmacology
Kawabe M,Nishida T,Horita C,Ikeda A,Takahashi R,Inui A,Shiozaki K
Tue Aug 30 00:00:00 EDT 2022
SARS-CoV-2 triggers Golgi fragmentation via down-regulation of GRASP55 to facilitate viral trafficking.
bioRxiv : the preprint server for biology
Zhang J,Kennedy A,Xing L,Bui S,Reid W,Joppich J,Ahat E,Rose M,Tang Q,Tai AW,Wang Y
Wed Mar 09 00:00:00 EST 2022
Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer's Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway.
Oxidative medicine and cellular longevity
Yin Z,Gao D,Du K,Han C,Liu Y,Wang Y,Gao X
Mon Apr 04 00:00:00 EDT 2022
Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Frontiers in immunology
Wang Q,Sun Z,Cao S,Lin X,Wu M,Li Y,Yin J,Zhou W,Huang S,Zhang A,Zhang Y,Xia W,Jia Z
Tue Jul 19 00:00:00 EDT 2022
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.
Journal of medicinal chemistry
Liu Y,Li Q,Gu M,Lu D,Xiong X,Zhang Z,Pan Y,Liao Y,Ding Q,Gong W,Chen DS,Guan M,Wu J,Tian Z,Deng H,Gu L,Hong X,Xiao Y
Thu Feb 10 00:00:00 EST 2022
miR-381-3p Cooperated With Hes1 to Regulate the Proliferation and Differentiation of Retinal Progenitor Cells.
Frontiers in cell and developmental biology
Wang J,Sun N,Ju Y,Ni N,Tang Z,Zhang D,Dai X,Chen M,Wang Y,Gu P,Ji J
Wed Mar 16 00:00:00 EDT 2022
¿yclooxygenase-2 Inhibitor Parecoxib Reduces LPS-Induced Activation of BV2 Microglia Cells.
Bulletin of experimental biology and medicine
Li X,Zhou JX,Qu YD,Kuang X
Thu Dec 01 00:00:00 EST 2022
Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.
International journal of molecular sciences
Zhang J,Yao P,Han W,Luo Y,Li Y,Yang Y,Xia H,Chen Z,Chen Q,Wang H,Yang L,Li H,Hu C,Huang H,Peng Z,Tan X,Li M,Yang J
Mon May 30 00:00:00 EDT 2022
2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation.
Biochemical pharmacology
Sun X,Fan T,Sun G,Zhou Y,Huang Y,Zhang N,Zhao L,Zhong R,Peng Y
Sun May 01 00:00:00 EDT 2022
Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.
Food & function
Liu J,Sun M,Xia Y,Cui X,Jiang J
Mon Jun 20 00:00:00 EDT 2022
A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells.
Brain research bulletin
Zhang Y,Wu Q,Ren Y,Zhang Y,Feng L
Sun May 01 00:00:00 EDT 2022
Inhibition of RNF182 mediated by Bap promotes non-small cell lung cancer progression.
Frontiers in oncology
Liu Y,Ouyang L,Mao C,Chen Y,Liu N,Chen L,Shi Y,Xiao D,Liu S,Tao Y
Wed Feb 01 00:00:00 EST 2023
MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response.
Journal of inflammation research
Yang L,Sun L,Cao Y,Wang Q,Song A,Zhu R,Liu W,Lu S
Tue Jul 26 00:00:00 EDT 2022
Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling.
Cellular and molecular life sciences : CMLS
Chen M,Shan L,Gan Y,Tian L,Zhou J,Zhu E,Yuan H,Li X,Wang B
Sun Jan 30 00:00:00 EST 2022
The role of reelin in the pathological mechanism of depression from clinical to rodents.
Psychiatry research
Jin K,Zhang S,Jiang C,Liu R,Chen B,Zhao H,Zhang Q,Shen Z,Xu P,Hu X,Jiao J,Lu J,Huang M
Tue Nov 01 00:00:00 EDT 2022
High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p.
Frontiers in oncology
Chen H,Zeng B,Li X,Zhao Q,Liu D,Chen Y,Zhang Y,Wang J,Xing HR
Sun Nov 05 00:00:00 EDT 2023
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration.
Epigenetics
Luo G,Xu W,Chen X,Wang S,Wang J,Dong F,Hu DN,Reinach PS,Yan D
Mon Aug 01 00:00:00 EDT 2022
Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation.
Experimental & molecular medicine
Chen S,Lei L,Li Z,Chen F,Huang Y,Jiang G,Guo X,Zhao Z,Liu H,Wang H,Liu C,Zheng Z,Wang J
Fri Apr 01 00:00:00 EDT 2022
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Journal of agricultural and food chemistry
Wang J,Zhang G,Yang Y,Zhang X,Shi K,Zhang X,Yan T,Jia Y
Wed Nov 09 00:00:00 EST 2022
NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway.
Genes & genomics
Zhang X,Chen Y,Wang X,Zhang Z,Wang J,Shen Y,Hu Y,Wu X
Tue Nov 01 00:00:00 EDT 2022
Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling.
BMC women's health
Yang X,Wang K,Lang J,Guo D,Gao H,Qiu Y,Jin X,Zhang M,Shi J,Ma Q,Ma Q,Wen Z
Sat Oct 08 00:00:00 EDT 2022
Hippocampal AMPA receptors mediate the impairment of spatial learning and memory in prenatally stressed offspring rats.
Journal of psychiatric research
Yao D,Mu Y,Lu Y,Li L,Shao S,Zhou J,Li J,Chen S,Zhang D,Zhang Y,Zhu Z,Li H
Fri Jul 01 00:00:00 EDT 2022
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Cellular signalling
Li X,Zhu M,Zhao G,Zhou A,Min L,Liu S,Zhang N,Zhu S,Guo Q,Zhang S,Li P
Sun May 01 00:00:00 EDT 2022
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Cancers
Xie Y,Shi Z,Qian Y,Jiang C,Liu W,Liu B,Jiang B
Sat Jul 23 00:00:00 EDT 2022
The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.
Cellular and molecular life sciences : CMLS
Wang LN,Wang L,Cheng G,Dai M,Yu Y,Teng G,Zhao J,Xu D
Mon Jan 31 00:00:00 EST 2022
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells.
Molecular brain
Liang J,Shen Y,Wang Y,Huang Y,Wang J,Zhu Q,Tong G,Yu K,Cao W,Wang Q,Li Y,Zhao Y
Mon Jun 20 00:00:00 EDT 2022
LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
Journal of experimental & clinical cancer research : CR
Li D,Shen L,Zhang X,Chen Z,Huang P,Huang C,Qin S
Fri Dec 02 00:00:00 EST 2022
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
International immunopharmacology
Han Y,Xian Y,Gao X,Qiang P,Hao J,Yang F,Shimosawa T,Chang Y,Xu Q
Thu Dec 01 00:00:00 EST 2022
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Peptides
Hu S,He L,Chen B,You Y
Sat Oct 01 00:00:00 EDT 2022
Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway.
Cardiovascular toxicology
Li Q,Zuo Z,Pan Y,Zhang Q,Xu L,Jiang B
Thu Sep 01 00:00:00 EDT 2022
PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis.
Cell structure and function
Ryu K,Yoshida A,Funato Y,Yamazaki D,Miki H
Thu Dec 15 00:00:00 EST 2022
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
Biochemical and biophysical research communications
Shi C,Pei M,Wang Y,Chen Q,Cao P,Zhang L,Guo J,Deng W,Wang L,Li X,Gong Z
Sat Feb 26 00:00:00 EST 2022
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Journal of ethnopharmacology
Xi P,Niu Y,Zhang Y,Li W,Gao F,Gu W,Kui F,Liu Z,Lu L,Du G
Tue Jun 28 00:00:00 EDT 2022
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Experimental hematology
Liu F,Zhao Q,Su Y,Lv J,Gai Y,Liu S,Lin H,Wang Y,Wang G
Sat Jan 01 00:00:00 EST 2022
Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.
Journal of inorganic biochemistry
Wu Y,Liu J,Shao M,Zhang P,Song S,Yang G,Liu X,Liu Z
Mon Aug 01 00:00:00 EDT 2022
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Cell and tissue research
Bian Y,Shi C,Song S,Mu L,Wu M,Qiu D,Dong J,Zhang W,Yuan C,Wang D,Zhou Z,Dong X,Shi Y
Sat Oct 01 00:00:00 EDT 2022
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification.
BMC complementary medicine and therapies
Lu S,Meng Z,Tan Y,Wu C,Huang Z,Huang J,Fu C,Stalin A,Guo S,Liu X,You L,Li X,Zhang J,Zhou W,Zhang X,Wang M,Wu J
Wed Mar 02 00:00:00 EST 2022
Enterobacter cloacae: a villain in CaOx stone disease?
Urolithiasis
Yang Y,Hong S,Xu J,Li C,Wang S,Xun Y
Fri Apr 01 00:00:00 EDT 2022
Identification of the effect and mechanism of Yiyi Fuzi Baijiang powder against colorectal cancer using network pharmacology and experimental validation.
Frontiers in pharmacology
Xiang B,Geng R,Zhang Z,Ji X,Zou J,Chen L,Liu J
Fri Nov 11 00:00:00 EST 2022
Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis.
Oxidative medicine and cellular longevity
Chen M,Liu M,Luo Y,Cao J,Zeng F,Yang L,Yang J,Tao T,Jiang Y
Fri Mar 04 00:00:00 EST 2022
Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway.
Molecular medicine reports
Sun F,Geng H,Sun Y,Feng W,Tian T,Ye L,Lei M
Fri Apr 01 00:00:00 EDT 2022
Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide/cigarette smoke-induced mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang HH,Zhou XJ,Zhong YS,Ji LT,Yu WY,Fang J,Ying HZ,Li CY
Wed Jun 01 00:00:00 EDT 2022
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.
Frontiers in molecular biosciences
Akiyama Y,Lyons SM,Fay MM,Tomioka Y,Abe T,Anderson PJ,Ivanov P
Fri Dec 16 00:00:00 EST 2022
Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop.
Nutrients
Tang H,Zheng Z,Wang H,Wang L,Zhao G,Wang P
Mon Apr 04 00:00:00 EDT 2022
Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.
Frontiers in immunology
Hu H,Fu M,Li C,Zhang B,Li Y,Hu Q,Zhang M
Tue Oct 11 00:00:00 EDT 2022
Dishevelled-Associated Activator of Morphogenesis 2 (DAAM2) Predicts the Immuno-Hot Phenotype in Pancreatic Adenocarcinoma.
Frontiers in molecular biosciences
Zhang Q,Pan J,Nie H,Wang H,An F,Zhan Q
Wed Mar 16 00:00:00 EDT 2022
RTCB Complex Regulates Stress-Induced tRNA Cleavage.
International journal of molecular sciences
Akiyama Y,Takenaka Y,Kasahara T,Abe T,Tomioka Y,Ivanov P
Fri Oct 28 00:00:00 EDT 2022
Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2.
Cancers
Cao F,Yang D,Tang F,Lu C,He X,Chen S,Yang Z,Gong S,Sun L,Enomoto A,Takahashi M,Weng L
Sat Nov 19 00:00:00 EST 2022
Manganese-Based Prussian Blue Nanocatalysts Suppress Non-Small Cell Lung Cancer Growth and Metastasis via Photothermal and Chemodynamic Therapy.
Frontiers in bioengineering and biotechnology
Fang D,Liu Z,Jin H,Huang X,Shi Y,Ben S
Sat Jul 16 00:00:00 EDT 2022
Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.
European journal of pharmacology
Peng Z,Wangmu T,Li L,Han G,Huang D,Yi P
Thu May 05 00:00:00 EDT 2022
MEF2D-NR4A1-FAM134B2-mediated reticulophagy contributes to amino acid homeostasis.
Autophagy
Shiozaki Y,Miyazaki-Anzai S,Keenan AL,Miyazaki M
Sun May 01 00:00:00 EDT 2022
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
CNS neuroscience & therapeutics
Zhang H,Wang Y,Zhao Y,Liu T,Wang Z,Zhang N,Dai Z,Wu W,Cao H,Feng S,Zhang L,Cheng Q,Liu Z
Tue Nov 01 00:00:00 EDT 2022
Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism.
Journal of proteomics
Wu YY,Yang C,Yan HJ,Lu P,Zhang L,Feng WC,Long YS
Sun Oct 30 00:00:00 EDT 2022
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Evidence-based complementary and alternative medicine : eCAM
Zhang Y,Wang D,Wu K,Shao X,Diao H,Wang Z,Sun M,Huang X,Li Y,Tang X,Yan M,Guo J
Sat Jul 16 00:00:00 EDT 2022
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Nature communications
Yang R,Yang C,Ma L,Zhao Y,Guo Z,Niu J,Chu Q,Ma Y,Li B
Thu Nov 17 00:00:00 EST 2022
Trilobatin promotes angiogenesis after cerebral ischemia-reperfusion injury via SIRT7/VEGFA signaling pathway in rats.
Phytotherapy research : PTR
Huang F,Luo L,Wu Y,Xia D,Xu F,Gao J,Shi J,Gong Q
Fri Jul 01 00:00:00 EDT 2022
Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.
Biochemical and biophysical research communications
Li J,Jiang R,Hou Y,Lin A
Sat Aug 27 00:00:00 EDT 2022
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Medical oncology (Northwood, London, England)
Gao L,Ye Z,Liu JH,Yang JA,Li Y,Cai JY,Wang YX,Tong SA,Deng G,Zhang S,Chen QX
Sun May 15 00:00:00 EDT 2022
Melatonin Maintains Homeostasis and Potentiates the Anti-inflammatory Response in Staphylococcus aureus-Induced Mastitis through microRNA-16b/YAP1.
Journal of agricultural and food chemistry
Chen Z,Wang K,Guo J,Zhou J,Loor JJ,Yang Z,Yang Y
Wed Dec 07 00:00:00 EST 2022
Molecular Mechanisms Underlying the Effects of Bimin Kang Mixture on Allergic Rhinitis: Network Pharmacology and RNA Sequencing Analysis.
BioMed research international
Qi LJ,Wang RZ,Gao S,Chen XJ,Zhang X,Zhang YP
Tue Nov 08 00:00:00 EST 2022
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nature communications
Wei B,Zhang T,Wang P,Pan Y,Li J,Chen W,Zhang M,Ji Q,Wu W,Lan L,Gan J,Yang CG
Mon Nov 14 00:00:00 EST 2022
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Journal of neuroinflammation
Chen J,Chang Y,Zhu J,Peng Y,Li Z,Zhang K,Zhang Y,Lin C,Lin Z,Pan S,Huang K
Thu Sep 01 00:00:00 EDT 2022
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
Frontiers in pharmacology
You X,Wu Y,Li Q,Sheng W,Zhou Q,Fu W
Tue Jul 19 00:00:00 EDT 2022
Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy.
Heliyon
Saraswat A,Vemana HP,Dukhande VV,Patel K
Sat Jan 01 00:00:00 EST 2022
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Frontiers in cellular and infection microbiology
Corliss L,Holliday M,Lennemann NJ
Mon Nov 21 00:00:00 EST 2022
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Diabetes
Niu Y,Jiang H,Yin H,Wang F,Hu R,Hu X,Peng B,Shu Y,Li Z,Chen S,Guo F
Sun May 01 00:00:00 EDT 2022
Propofol Augments Paclitaxel-Induced Cervical Cancer Cell Ferroptosis In Vitro.
Frontiers in pharmacology
Zhao MY,Liu P,Sun C,Pei LJ,Huang YG
Sat Jul 16 00:00:00 EDT 2022
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions.
Regenerative therapy
Morita K,Nakamura A,Machida M,Kawasaki T,Nakanishi R,Ichida J,Iwata T,Umezawa A,Akutsu H
Thu Dec 01 00:00:00 EST 2022
Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.
Molecular therapy. Nucleic acids
Zhang Y,Xi X,Yu H,Yang L,Lin J,Yang W,Liu J,Fan X,Xu Y
Tue Sep 13 00:00:00 EDT 2022
Exploring Active Ingredients, Beneficial Effects, and Potential Mechanism of Allium tenuissimum L. Flower for Treating T2DM Mice Based on Network Pharmacology and Gut Microbiota.
Nutrients
Zhang SS,Hou YF,Liu SJ,Guo S,Ho CT,Bai NS
Sun Sep 25 00:00:00 EDT 2022
Inhibition of progesterone receptor membrane component-1 exacerbates neonatal hypoxic-ischemic cerebral damage in male mice.
Experimental neurology
Sun X,Hu Y,Zhou H,Wang S,Zhou C,Lin L,Zhu T,Ge J,Han J,Zhou Y,Jin G,Wang Y,Zu J,Shi H,Yang X,Zan K,Wang J,Hua F
Sat Jan 01 00:00:00 EST 2022
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Frontiers in oncology
Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P
Sat May 07 00:00:00 EDT 2022
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Proceedings of the National Academy of Sciences of the United States of America
Yu J,Liufu T,Zheng Y,Xu J,Meng L,Zhang W,Yuan Y,Hong D,Charlet-Berguerand N,Wang Z,Deng J
Tue Oct 11 00:00:00 EDT 2022
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
International immunopharmacology
Huo K,Ma KG,Guo QY,Duan P,Xu J
Fri Jul 01 00:00:00 EDT 2022
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Cell death & disease
Li J,Lai M,Zhang X,Li Z,Yang D,Zhao M,Wang D,Sun Z,Ehsan S,Li W,Gao H,Zhao D,Yang L
Fri Feb 18 00:00:00 EST 2022
Flavonoid extract of saffron by-product alleviates hyperuricemia via inhibiting xanthine oxidase and modulating gut microbiota.
Phytotherapy research : PTR
Chen N,Wang R,Li H,Wang W,Wang L,Yin X,Yao R,Yang B
Thu Dec 01 00:00:00 EST 2022
Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jin H,Jiang N,Xu W,Zhang Z,Yang Y,Zhang J,Xu H
Thu Sep 01 00:00:00 EDT 2022
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
Cellular and molecular gastroenterology and hepatology
Chen S,Wu H,Wang Z,Jia M,Guo J,Jin J,Li X,Meng D,Lin L,He AR,Zhou P,Zhi X
Mon Apr 04 00:00:00 EDT 2022
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
Journal of virology
Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X
Wed Sep 14 00:00:00 EDT 2022
Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.
Life science alliance
Rusilowicz-Jones EV,Barone FG,Lopes FM,Stephen E,Mortiboys H,Urbé S,Clague MJ
Tue Feb 01 00:00:00 EST 2022
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Chinese medicine
Pan B,Xia Y,Gao Z,Zhao G,Wang L,Fang S,Liu L,Yan S
Wed Mar 09 00:00:00 EST 2022
Stain-Free total-protein normalization enhances the reproducibility of Western blot data.
Analytical biochemistry
Maloy A,Alexander S,Andreas A,Nyunoya T,Chandra D
Sat Oct 01 00:00:00 EDT 2022
PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.
Journal of experimental & clinical cancer research : CR
Wang L,Li S,Luo H,Lu Q,Yu S
Fri Oct 14 00:00:00 EDT 2022
Effects of Capsaicin on the Hypoglycemic Regulation of Metformin and Gut Microbiota Profiles in Type 2 Diabetic Rats.
The American journal of Chinese medicine
Kang ZQ,Hu JL,Chen MY,Mao Y,Xie LF,Yang N,Liu T,Zhang W,Huang WH
Thu Apr 28 00:00:00 EDT 2022
MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5.
Toxicon : official journal of the International Society on Toxinology
Zhao N,Yu H,Xi Y,Dong M,Wang Y,Sun C,Zhang J,Xu N,Liu W
Wed Jun 01 00:00:00 EDT 2022
Asperosaponin VI protects mice from sepsis by regulating Hippo and Rho signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Pang C,Wen C,Liang Y,Luo H,Wei L,Liu H,Qin T,Tan H,He C,Liu Y,Chen Y,Zeng S,Zhou C
Sun May 01 00:00:00 EDT 2022
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Gong Z,Da W,Tian Y,Zhao R,Qiu S,Wu Q,Wen K,Shen L,Zhou R,Tao L,Zhu Y
Tue Feb 01 00:00:00 EST 2022
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Cell cycle (Georgetown, Tex.)
Wen C,Lin L,Zou R,Lin F,Liu Y
Tue Feb 01 00:00:00 EST 2022
SARS-CoV-2 productively infects human brain microvascular endothelial cells.
Journal of neuroinflammation
Yang RC,Huang K,Zhang HP,Li L,Zhang YF,Tan C,Chen HC,Jin ML,Wang XR
Wed Jun 15 00:00:00 EDT 2022
Monochromatic Light Pollution Exacerbates High-Fat Diet-Induced Adipocytic Hypertrophy in Mice.
Cells
Guan Q,Li Y,Wang Z,Cao J,Dong Y,Ren F,Chen Y
Mon Nov 28 00:00:00 EST 2022
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
Precision clinical medicine
Luo P,Chen J,Zhang Q,Xia F,Wang C,Bai Y,Tang H,Liu D,Gu L,Du Q,Xiao W,Yang C,Wang J
Thu Dec 01 00:00:00 EST 2022
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Inflammation
Chen Q,Lu H,Duan C,Zhu X,Zhang Y,Li M,Zhang D
Tue Feb 01 00:00:00 EST 2022
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
Cell communication and signaling : CCS
Zhang Y,Zhang C,Li J,Jiang M,Guo S,Yang G,Zhang L,Wang F,Yi S,Wang J,Fu Y,Zhang Y
Fri Jun 17 00:00:00 EDT 2022
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
The Tohoku journal of experimental medicine
Xie T,Yang R,Zhang X,Shen X,Yu L,Liao J,Bao T,Fang Q
Wed Dec 14 00:00:00 EST 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 EST 2022
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Veterinary sciences
Li Z,Hu J,Wang X,Du Y,Yin J,Gao J,Han B,Cui S,Liu Y,Liu J
Tue Jul 26 00:00:00 EDT 2022
Fucosylated Chondroitin Sulfate against Parkinson's Disease through Inhibiting Inflammation Induced by Gut Dysbiosis.
Journal of agricultural and food chemistry
Liu Y,Liu X,Ye Q,Wang Y,Zhang J,Lin S,Wang G,Yang X,Zhang J,Chen S,Wu N
Wed Oct 26 00:00:00 EDT 2022
Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research.
Frontiers in neurology
Liu W,Zhang Q,Xing H,Gao G,Liu J,Huang Y,Yang H
Tue Mar 08 00:00:00 EST 2022
Prognostic and functional role of hyaluronan-binding protein 1 in pancreatic ductal adenocarcinoma.
Oncology letters
Adachi Y,Sato N,Oba T,Amaike T,Kudo Y,Kohi S,Nakayama T,Hirata K
Fri Jul 01 00:00:00 EDT 2022
FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy.
Frontiers in oncology
Zhang Y,Wu T,Li F,Cheng Y,Han Q,Lu X,Lu S,Xia W
Sat Jul 16 00:00:00 EDT 2022
Heterozygous FMN2 missense variant found in a family case of premature ovarian insufficiency.
Journal of ovarian research
Li J,Peng T,Wang L,Long P,Quan R,Tan H,Zeng M,Wu X,Yang J,Xiao H,Shi X
Mon Feb 28 00:00:00 EST 2022
N6-methyladenosine RNA demethylase ALKBH5 is testis-specifically downregulated in hybrid male sterile dzo and is a target gene of bta-miR-200a.
Theriogenology
Chen H,Zhang J,Yan Y,Zhu C,Wang L,Fu S,Zuo F,Zhang GW
Fri Jul 15 00:00:00 EDT 2022
Expression of POT1-AS1 in GC Tissue, Its Effect on Biological Behavior of Gastric Cancer, and Its Significance on Prognosis of Gastric Cancer.
Computational and mathematical methods in medicine
Jiang L,Yang L,Dai Y,Yang G,Pan S
Tue Aug 09 00:00:00 EDT 2022
Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway.
Frontiers in pharmacology
Yang X,Yao L,Yuan M,Zhang X,Jakubowska MA,Ferdek PE,Dai L,Yang J,Jin T,Deng L,Fu X,Du D,Liu T,Criddle DN,Sutton R,Huang W,Xia Q
Sat Jul 16 00:00:00 EDT 2022
Lithocarpus polystachyus (Sweet Tea) water extract promotes human hepatocytes HL7702 proliferation through activation of HGF/AKT/ERK signaling pathway.
Chinese herbal medicines
Lei M,Chen N,Xu Y,Gong Q,Gao J
Sat Oct 01 00:00:00 EDT 2022
Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness.
Clinical and translational medicine
Wang L,Zhao L,Lin Z,Yu D,Jin M,Zhou P,Ren J,Cheng J,Yang K,Wu G,Zhang T,Zhang D
Sun May 01 00:00:00 EDT 2022
COP1 Acts as a Ubiquitin Ligase for PCDH9 Ubiquitination and Degradation in Human Glioma.
Molecular neurobiology
Zhou K,Wang L,Sun Z,Liu Y,Zhu Y,Liu Z,Zhang B,Shi H
Fri Apr 01 00:00:00 EDT 2022
lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.
BioMed research international
Ma Y,Yu L,Yan W,Qiu L,Zhang J,Jia X
Mon Jan 31 00:00:00 EST 2022
Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production.
Cells
Cornell D,Miwa S,Georgiou M,Anderson SJ,Honkanen-Scott M,Shaw JAM,Arden C
Fri Jul 29 00:00:00 EDT 2022
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.
Journal of translational medicine
Wang Z,Wang MM,Geng Y,Ye CY,Zang YS
Mon Sep 05 00:00:00 EDT 2022
Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication.
Antioxidants (Basel, Switzerland)
Liang X,Li Y,Chu P,Wang Q,Wang H,Liao L,Yang C,Zhu Z,Wang Y,He L
Thu Sep 29 00:00:00 EDT 2022
HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation.
Oxidative medicine and cellular longevity
Chang Y,Wu Y,Jiang X,Zhu J,Wang C,Ma R,Li G
Mon Aug 15 00:00:00 EDT 2022
Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment.
NPJ precision oncology
Shi X,Li Z,Yao R,Cheng Q,Li W,Wu R,Xie Z,Zhu Y,Qiu X,Yang S,Zhou T,Hu J,Zhang Y,Wu T,Zhao Y,Zhang Y,Wu J,Wang H,Jiang X,Chen L
Thu Aug 18 00:00:00 EDT 2022
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.
Cell research
Hu CL,Chen BY,Li Z,Yang T,Xu CH,Yang R,Yu PC,Zhao J,Liu T,Liu N,Shan B,Zhang Q,Song J,Fei MY,Zong LJ,Zhang JY,Wu JC,Chen SB,Wang Y,Chang B,Hou D,Liu P,Jiang Y,Li X,Chen X,Deng CH,Ren YY,Wang R,Jin J,Xue K,Zhang Y,Du M,Shi J,Wu LY,Chang CK,Shen S,Chen Z,Chen SJ,Liu X,Sun XJ,Zheng M,Wang L
Thu Dec 01 00:00:00 EST 2022
Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway.
Brain research bulletin
Yao H,Zhao J,Song X
Thu Sep 01 00:00:00 EDT 2022
The lncRNA KIF9-AS1 Accelerates Hepatocellular Carcinoma Growth by Recruiting DNMT1 to Promote RAI2 DNA Methylation.
Journal of oncology
Yu Y,Lu X,Yan Y,Wang Y,Meng J,Tian S,Mu J
Tue Oct 25 00:00:00 EDT 2022
LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.
Acta pharmaceutica Sinica. B
Sun J,Jin T,Niu Z,Guo J,Guo Y,Yang R,Wang Q,Gao H,Zhang Y,Li T,He W,Li Z,Ma W,Su W,Li L,Fan X,Shan H,Liang H
Thu Sep 01 00:00:00 EDT 2022
LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24.
Molecular therapy. Nucleic acids
Lv T,Jin Y,Miao Y,Xu T,Jia F,Feng H,Zhang X
Tue Mar 08 00:00:00 EST 2022
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Oxidative medicine and cellular longevity
Song J,Sheng J,Lei J,Gan W,Yang Y
Wed Oct 05 00:00:00 EDT 2022
Allyl methyl trisulfide protected against LPS-induced acute lung injury in mice via inhibition of the NF-κB and MAPK pathways.
Frontiers in pharmacology
Wang S,Liu J,Dong J,Fan Z,Wang F,Wu P,Li X,Kou R,Chen F
Fri Aug 26 00:00:00 EDT 2022
Long non-coding RNA NEAT1 promotes angiogenesis in hepatoma carcinoma via the miR-125a-5p/VEGF pathway.
Open life sciences
Guo J,Yuan Q,Fang Y,Liao J,Zhang Z
Tue Oct 11 00:00:00 EDT 2022
Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model.
Cancer letters
Wang SC,Yu CY,Wu YC,Chang YC,Chen SL,Sung WW
Fri Apr 01 00:00:00 EDT 2022
Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.
Phytotherapy research : PTR
Ding Y,Wang L,Liu B,Ren G,Okubo R,Yu J,Zhang C
Sat Oct 01 00:00:00 EDT 2022
Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.
Frontiers in pharmacology
Zhang T,Liu M,Liu Q,Xiao GG
Wed Jan 11 00:00:00 EST 2023
Retrospective analysis of the efficacy of adjuvant cytokine-induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery.
Clinical & translational immunology
Li X,Zhou H,Huang W,Wang X,Meng M,Hou Z,Liao L,Tang W,Xie Y,Wang R,Yu H,Wang L,Zhu H,Wang W,Tan J,Li R
Sat Apr 30 00:00:00 EDT 2022
PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Zhang Z,Huang Y,Xu N,Wang J,Yao T,Xu Y,Qiao D,Gao J,Shen S,Ma J
Tue Apr 05 00:00:00 EDT 2022
FumDSB can alleviate the inflammatory response induced by fumonisin B1 in growing pigs.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Liu Q,Huang L,Cui Z,Qiao B,Li F,Wang C
Thu Sep 01 00:00:00 EDT 2022
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Molecules (Basel, Switzerland)
Peng J,Cai Z,Wang Q,Zhou J,Xu J,Pan D,Chen T,Zhang G,Tao L,Chen Y,Shen X
Sat Jun 04 00:00:00 EDT 2022
Paeoniflorin ameliorates diabetic liver injury by targeting the TXNIP-mediated NLRP3 inflammasome in db/db mice.
International immunopharmacology
Wang A,Gong Y,Pei Z,Jiang L,Xia L,Wu Y
Mon Aug 01 00:00:00 EDT 2022
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Cell death & disease
Yi L,Shang XJ,Lv L,Wang Y,Zhang J,Quan C,Shi Y,Liu Y,Zhang L
Sat Nov 05 00:00:00 EDT 2022
Inducement of ER Stress by PAD Inhibitor BB-Cl-Amidine to Effectively Kill AML Cells.
Current medical science
Sun YN,Ma YN,Jia XQ,Yao Q,Chen JP,Li H
Sat Oct 01 00:00:00 EDT 2022
Capnocytophaga gingivalis is a potential tumor promotor in oral cancer.
Oral diseases
Zhu W,Shen W,Wang J,Xu Y,Zhai R,Zhang J,Wang M,Wang M,Liu L
Mon Sep 12 00:00:00 EDT 2022
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.
Frontiers in pharmacology
Gao T,Xu J,Xiao Y,Li J,Hu W,Su X,Shen X,Yu W,Chen Z,Huang B,Li H,Wang X
Tue Sep 20 00:00:00 EDT 2022
The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.
Biochimica et biophysica acta. Molecular basis of disease
Wang G,Duan J,Pu G,Ye C,Li Y,Xiu W,Xu J,Liu B,Zhu Y,Wang C
Mon Aug 01 00:00:00 EDT 2022
Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.
Frontiers in neurology
He CF,Xue WJ,Xu XD,Wang JT,Wang XR,Feng Y,Zhou HG,Guo JC
Sat Jul 16 00:00:00 EDT 2022
PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway.
International journal of biological macromolecules
Chen H,Zhong J,Li J,Zeng Z,Yu Q,Yan C
Sat Jan 01 00:00:00 EST 2022
Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.
Mechanisms of ageing and development
Jiang N,Xing B,Peng R,Shang J,Wu B,Xiao P,Lin S,Xu X,Lu H
Fri Jul 01 00:00:00 EDT 2022
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma.
Cellular and molecular gastroenterology and hepatology
Zhu GQ,Wang Y,Wang B,Liu WR,Dong SS,Chen EB,Cai JL,Wan JL,Du JX,Song LN,Chen SP,Yu L,Zhou ZJ,Wang Z,Zhou J,Shi YH,Fan J,Dai Z
Mon Apr 18 00:00:00 EDT 2022
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Frontiers in oncology
Kang X,Huo Y,Jia S,He F,Li H,Zhou Q,Chang N,Liu D,Li R,Hu Y,Zhang P,Xu A
Tue Jul 26 00:00:00 EDT 2022
De novo pyrimidine synthesis fuels glycolysis and confers chemoresistance in gastric cancer.
Cancer letters
He D,Chen M,Chang L,Gu J,Liu F,Gao X,Ruan Y
Mon Nov 28 00:00:00 EST 2022
Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
Journal of medicinal chemistry
Li N,Yang H,Liu K,Zhou L,Huang Y,Cao D,Li Y,Sun Y,Yu A,Du Z,Yu F,Zhang Y,Wang B,Geng M,Li J,Xiong B,Xu S,Huang X,Liu T
Thu Jul 14 00:00:00 EDT 2022
Proteomic Analysis of Vero Cells Infected with Pseudorabies Virus.
Viruses
Yang X,Xu S,Chen D,Jiang R,Kang H,Ge X,Zhou L,Han J,Zhang Y,Guo X,Yang H
Mon Apr 04 00:00:00 EDT 2022
ATG4B hinders porcine epidemic diarrhea virus replication through interacting with TRAF3 and activating type-I IFN signaling.
Veterinary microbiology
Dong S,Kong N,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Li Y,Tong G,Shan T
Sat Oct 01 00:00:00 EDT 2022
VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis.
Metabolism: clinical and experimental
Jia X,Bai X,Yang X,Wang L,Lu Y,Zhu L,Zhao Y,Cheng W,Shu M,Mei Q,Jin S
Sat Oct 01 00:00:00 EDT 2022
Neuregulin-1β increases glucose uptake and promotes GLUT4 translocation in palmitate-treated C2C12 myotubes by activating PI3K/AKT signaling pathway.
Frontiers in pharmacology
Yu M,Wu S,Gong C,Chen L
Thu Feb 02 00:00:00 EST 2023
A Dual-Action Molecule Suppresses S. aureus Infection as an Inhibitor Targeting Hla Pore Formation and TLR2 Signaling.
Advanced biology
Wang T,Jiang F,Su J,Chu X,Cao Y,Lv H,Deng X,Wang J
Sat Oct 01 00:00:00 EDT 2022
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Frontiers in microbiology
Xu M,Liu Y,Mayinuer T,Lin Y,Wang Y,Gao J,Wang D,Kastelic JP,Han B
Sat Aug 13 00:00:00 EDT 2022
Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.
Nutrition and cancer
Khedr OMS,El-Sonbaty SM,Moawed FSM,Kandil EI,Abdel-Maksoud BE
Wed Apr 13 00:00:00 EDT 2022
Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.
Cancer science
Funasaki S,Mehanna S,Ma W,Nishizawa H,Kamikubo Y,Sugiyama H,Ikeda S,Motoshima T,Hasumi H,Linehan WM,Schmidt LS,Ricketts C,Suda T,Oike Y,Kamba T,Baba M
Fri Jul 01 00:00:00 EDT 2022
Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Acute Respiratory Distress Syndrome Mouse Model.
Pathogens (Basel, Switzerland)
Wu X,Ma C,Ma Q,Zhuang P,Deng G
Mon May 02 00:00:00 EDT 2022
TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection.
Virus research
Zhao P,Jing H,Dong W,Duan E,Ke W,Tao R,Li Y,Cao S,Wang H,Zhang Y,Sun Y,Wang J
Sat Apr 02 00:00:00 EDT 2022
Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.
Food & function
Luo L,Li R,Wang G,Chen J,Chen L,Qin LQ,Yu Z,Wan Z
Wed Apr 20 00:00:00 EDT 2022
Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function.
Nature communications
Erdogmus S,Concepcion AR,Yamashita M,Sidhu I,Tao AY,Li W,Rocha PP,Huang B,Garippa R,Lee B,Lee A,Hell JW,Lewis RS,Prakriya M,Feske S
Tue Apr 19 00:00:00 EDT 2022
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
Cell reports
Zhou X,Liu J,Zheng Y,Zhang Z,Wu Y,Yang W,Liu J,Huang Y,Yi Y,Zhao Z,Xiao H,Mo X,Wang J
Tue May 03 00:00:00 EDT 2022
The histone modification reader ZCWPW1 promotes double-strand break repair by regulating cross-talk of histone modifications and chromatin accessibility at meiotic hotspots.
Genome biology
Yuan S,Huang T,Bao Z,Wang S,Wu X,Liu J,Liu H,Chen ZJ
Tue Sep 06 00:00:00 EDT 2022
Inhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis.
Genetics research
Feng Y,Wang C,Wang G
Fri Nov 18 00:00:00 EST 2022
Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain.
Scientific reports
Zhang B,Peng X,Sun X,Guo Y,Li T
Wed Oct 26 00:00:00 EDT 2022
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
International journal of molecular sciences
Zou Y,Wang X,Xu J,Wang S,Li S,Zhu Y,Wang J
Mon Oct 31 00:00:00 EDT 2022
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Folia histochemica et cytobiologica
Xiong W,Huang XL,Li CY,Wang XL,Lan HW,Wang TT,Chen ZL,Yang QP,Hu AL,Xia YF,Zhu FR,Zhou ZZ
Mon Jan 02 00:00:00 EST 2023
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Bioorganic chemistry
Gong X,He Y,Yang D,Yang S,Li J,Zhao H,Chen Q,Ren Q,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway.
Nutrients
Li J,Fan Y,Zhang Y,Liu Y,Yu Y,Ma M
Fri Jun 10 00:00:00 EDT 2022
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Journal of molecular neuroscience : MN
Peng X,Wang J,Peng J,Jiang H,Le K
Sat Jan 01 00:00:00 EST 2022
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Cell death & disease
Qin T,Xiao Y,Qian W,Wang X,Gong M,Wang Q,An R,Han L,Duan W,Ma Q,Wang Z
Thu Apr 21 00:00:00 EDT 2022
High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice.
International immunopharmacology
Wang L,Ji T,Yuan Y,Fu H,Wang Y,Tian S,Hu J,Wang L,Wang Z
Mon Aug 01 00:00:00 EDT 2022
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation.
Biochemical and biophysical research communications
Zhang Y,Xie Y,Cheng Z,Xi K,Huang X,Kuang F,Wang W,Liu T,Guo B,Wu S
Sat Dec 03 00:00:00 EST 2022
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Oxidative medicine and cellular longevity
Yang CJ,Li X,Feng XQ,Chen Y,Feng JG,Jia J,Wei JC,Zhou J
Tue Aug 30 00:00:00 EDT 2022
Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway.
Psychopharmacology
Shen B,Zhang D,Zeng X,Guan L,Yang G,Liu L,Huang J,Li Y,Hong S,Li L
Sun May 01 00:00:00 EDT 2022
Effect of muscone on anti-apoptotic ability of muskrat prostate primary cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Zhang Y,Zhao X,Man X,Ma Y,Zhang W,Wang Y,Lei X,Bai S
Sat Oct 01 00:00:00 EDT 2022
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Metabolites
Zhang X,Li X,Xiong G,Yun F,Feng Y,Ni Q,Wu N,Yang L,Yi Z,Zhang Q,Yang Z,Kuang Y,Sai B,Zhu Y
Thu Nov 17 00:00:00 EST 2022
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Science advances
Gao S,Li X,Jiang Q,Liang Q,Zhang F,Li S,Zhang R,Luan J,Zhu J,Gu X,Xiao T,Huang H,Chen S,Ning W,Yang G,Yang C,Zhou H
Fri Sep 23 00:00:00 EDT 2022
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Laboratory investigation; a journal of technical methods and pathology
Lin W,Zhang X,Zhang C,Li L,Zhang J,Xie P,Zhan Y,An W
Sat Oct 01 00:00:00 EDT 2022
P-Coumaric Acid Reverses Depression-Like Behavior and Memory Deficit Via Inhibiting AGE-RAGE-Mediated Neuroinflammation.
Cells
Yu XD,Zhang D,Xiao CL,Zhou Y,Li X,Wang L,He Z,Reilly J,Xiao ZY,Shu X
Tue May 10 00:00:00 EDT 2022
SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation.
International journal of molecular sciences
Xie Q,Hua X,Huang C,Liao X,Tian Z,Xu J,Zhao Y,Jiang G,Huang H,Huang C
Wed Oct 19 00:00:00 EDT 2022
Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke.
Journal of nanobiotechnology
Wang C,Yang X,Jiang Y,Qi L,Zhuge D,Xu T,Guo Y,Deng M,Zhang W,Tian D,Yin Q,Li L,Zhang Z,Wang Y,Yang GY,Chen Y,Tang Y
Tue May 31 00:00:00 EDT 2022
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
International immunopharmacology
Yang L,Zhu J,Yang L,Gan Y,Hu D,Zhao J,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.
CNS neuroscience & therapeutics
Dong R,Lv P,Han Y,Jiang L,Wang Z,Peng L,Ma Z,Xia T,Zhang B,Gu X
Thu Dec 01 00:00:00 EST 2022
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Molecules (Basel, Switzerland)
Liu J,Li B,Liu J,Qiu F,Diao Y,Lei Y,Liu J,Zhang W
Tue Aug 16 00:00:00 EDT 2022
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Oxidative medicine and cellular longevity
Wu H,Wang Y,Chen X,Yao Y,Zhao W,Fang L,Sun X,Wang N,Jiang J,Gao L,Zhao J,Xu C
Fri Jul 15 00:00:00 EDT 2022
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations.
Oxidative medicine and cellular longevity
Wu H,Wang Y,Chen X,Yao Y,Zhao W,Fang L,Sun X,Wang N,Jiang J,Gao L,Zhao J,Xu C
Fri Jul 15 00:00:00 EDT 2022
Host Zinc-finger CCHC-type containing protein 3 inhibits pseudorabies virus proliferation by regulating type I interferon signaling.
Gene
Chen X,Shan T,Sun D,Zhai H,Dong S,Kong N,Zheng H,Tong W,Tong G
Wed Jun 15 00:00:00 EDT 2022
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
Carbohydrate polymers
Yang X,Huang L,Yi X,Huang S,Duan B,Yu A
Mon Aug 01 00:00:00 EDT 2022
NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
International journal of molecular sciences
Li X,Li Y,Li F,Chen Q,Zhao Z,Liu X,Zhang N,Li H
Tue Mar 22 00:00:00 EDT 2022
NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
International journal of molecular sciences
Li X,Li Y,Li F,Chen Q,Zhao Z,Liu X,Zhang N,Li H
Tue Mar 22 00:00:00 EDT 2022
NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
International journal of molecular sciences
Li X,Li Y,Li F,Chen Q,Zhao Z,Liu X,Zhang N,Li H
Tue Mar 22 00:00:00 EDT 2022
NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy.
International journal of molecular sciences
Li X,Li Y,Li F,Chen Q,Zhao Z,Liu X,Zhang N,Li H
Tue Mar 22 00:00:00 EDT 2022
Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).
Biochemical and biophysical research communications
Liu Y,Shi WD,Xie QQ,Wang JG,Gu CC,Ji ZH,Xiao J,Liu WQ
Sat May 14 00:00:00 EDT 2022
Intermittent fasting protects against Alzheimer's disease in mice by altering metabolism through remodeling of the gut microbiota.
Nature aging
Pan RY,Zhang J,Wang J,Wang Y,Li Z,Liao Y,Liao Y,Zhang C,Liu Z,Song L,Yu J,Yuan Z
Tue Nov 01 00:00:00 EDT 2022
Carrier-Free Delivery of Ultrasmall π-Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics.
Small (Weinheim an der Bergstrasse, Germany)
Zheng R,Zhao Q,Qing W,Li S,Liu Z,Li Q,Huang Y
Sat Jan 01 00:00:00 EST 2022
Atg6 promotes organismal health by suppression of cell stress and inflammation.
Cell death and differentiation
Shen JL,Doherty J,Allen E,Fortier TM,Baehrecke EH
Tue Nov 01 00:00:00 EDT 2022
Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy In Vivo and In Vitro.
Evidence-based complementary and alternative medicine : eCAM
Su Y,Kang Y,Yi J,Lin Q,Zhang C,Lin Z,Yan Z,Qu J,Liu J
Sun Nov 05 00:00:00 EDT 2023
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.
Biological & pharmaceutical bulletin
Cheng L,Wang T,Gao Z,Wu W,Cao Y,Wang L,Zhang Q
Tue May 03 00:00:00 EDT 2022
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Cell death & disease
Yao H,Ren D,Wang Y,Wu L,Wu Y,Wang W,Li Q,Liu L
Fri Sep 02 00:00:00 EDT 2022
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
Genes
Li J,Lan M,Peng J,Xiong Q,Xu Y,Yang Y,Zhou Y,Liu J,Zeng Z,Yang X,Zhang Z,Zhang P,Zhu Q,Wu W
Sat Apr 30 00:00:00 EDT 2022
KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer.
Cancer communications (London, England)
Liu C,Zheng S,Wang Z,Wang S,Wang X,Yang L,Xu H,Cao Z,Feng X,Xue Q,Wang Y,Sun N,He J
Thu Sep 01 00:00:00 EDT 2022
Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor types.
Frontiers in oncology
Hu A,Wang Y,Tian J,Chen Z,Chen R,Han X,Chen Y,Liu T,Chen Q
Thu Dec 22 00:00:00 EST 2022
TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells.
Scientific reports
Liu J,Shu G,Wu A,Zhang X,Zhou Z,Alvero AB,Mor G,Yin G
Mon Sep 19 00:00:00 EDT 2022
Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.
Experimental eye research
Yang J,Li Y,Gao W,Feng Y,He X,Ni H,Song X,Fan J
Wed Jun 01 00:00:00 EDT 2022
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
ACS chemical neuroscience
Qu D,Ye Z,Zhang W,Dai B,Chen G,Wang L,Shao X,Xiang A,Lu Z,Shi J
Wed Nov 02 00:00:00 EDT 2022
Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis.
JCI insight
Feng SY,Lei J,Li YX,Shi WG,Wang RR,Yap AU,Wang YX,Fu KY
Tue Nov 08 00:00:00 EST 2022
PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress.
Antioxidants (Basel, Switzerland)
Liu X,Xu M,Yu Y,Chen Y,Weng X,Zhu L
Sun Sep 18 00:00:00 EDT 2022
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis.
Molecular medicine reports
Wei W,Lin C,Hu R,Huang J,Chen X,Zhou L,Wei J,Deng YB,Wang CF
Tue Nov 01 00:00:00 EDT 2022
Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine.
Biomedicines
Wooten DJ,Sinha I,Sinha R
Tue Jan 11 00:00:00 EST 2022
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Toxicology research
Deng W,Sun Z,Chen S,Li G,Liu X,Huang L,Zhang Z
Mon Aug 01 00:00:00 EDT 2022
Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Shen P,Zhang T,Chen G,Zhang B,Huang A,Duan L,Zhu D,Chen J,Wang J,Duan Y
Sun May 01 00:00:00 EDT 2022
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ma Z,Xue X,Bai J,Cai Y,Jin X,Jia K,Ding M,Lyu X,Li X
Tue Nov 01 00:00:00 EDT 2022
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.
Nucleic acids research
Yang M,Wang C,Zhou M,Bao L,Wang Y,Kumar A,Xing C,Luo W,Wang Y
Fri Jun 24 00:00:00 EDT 2022
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
International journal of biological sciences
Dong L,Jiang H,Chen K,Xie J,An Q,Deng F,Sun Z,Liu Y,Zhou J,Zhang L,Lu X,Wang M,Chen Z,Zou X,Zuo D
Fri Apr 15 00:00:00 EDT 2022
Nuclear ribonucleoprotein RALY targets virus nucleocapsid protein and induces autophagy to restrict porcine epidemic diarrhea virus replication.
The Journal of biological chemistry
Qin W,Kong N,Zhang Y,Dong S,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Yu H,Zhang W,Tong G,Lan D,Tong W,Shan T
Mon Aug 01 00:00:00 EDT 2022
Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response.
Frontiers in immunology
Dou Y,Xie Y,Zhang L,Liu S,Xu D,Wei Y,Li Y,Zhang XL
Tue May 24 00:00:00 EDT 2022
Identification of pyroptosis-related lncRNA signature and AC005253.1 as a pyroptosis-related oncogene in prostate cancer.
Frontiers in oncology
Yu J,Tang R,Li J
Wed Oct 19 00:00:00 EDT 2022
DEXMEDETOMIDINE PREVENTS PDIA3 DECREASE BY ACTIVATING α2-ADRENERGIC RECEPTOR TO ALLEVIATE INTESTINAL I/R IN MICE.
Shock (Augusta, Ga.)
Zhan Y,Chen Z,Qiu Y,Deng Q,Huang W,Wen S,Shen J
Thu Dec 01 00:00:00 EST 2022
Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.
Frontiers in pharmacology
Ni YH,Deng HF,Zhou L,Huang CS,Wang NN,Yue LX,Li GF,Yu HJ,Zhou W,Gao Y
Tue Jul 26 00:00:00 EDT 2022
Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
International journal of molecular sciences
Liao TC,Huang JP,Tsai YT,Shih WC,Juan CC,Hsieh PS,Hung LM,Yu CL
Thu Oct 27 00:00:00 EDT 2022
Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion.
Stem cell research & therapy
Hu X,Pan J,Li Y,Jiang Y,Zheng H,Shi R,Zhang Q,Liu C,Tian H,Zhang Z,Tang Y,Yang GY,Wang Y
Thu Jan 20 00:00:00 EST 2022
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.
Toxins
Cheng D,Deng B,Tong Q,Gao S,Xiao B,Zhu M,Ren Z,Wang L,Sun M
Sun Apr 10 00:00:00 EDT 2022
CircRNA-001241 mediates sorafenib resistance of hepatocellular carcinoma cells by sponging miR-21-5p and regulating TIMP3 expression.
Gastroenterologia y hepatologia
Yang Q,Wu G
Thu Dec 01 00:00:00 EST 2022
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses.
Oncogene
Tu J,Fang Y,Han D,Tan X,Xu Z,Jiang H,Wang X,Hong W,Wei W
Fri Apr 01 00:00:00 EDT 2022
Interleukin-17A Contributed to the Damage of Blood-CNS Barriers During Streptococcus suis Meningitis.
Molecular neurobiology
Xu L,Lu X,Xiao P,Liu R,Xia K,Wu M,Jin M,Zhang A
Fri Apr 01 00:00:00 EDT 2022
Essential role of MESP1-RING1A complex in cardiac differentiation.
Developmental cell
Liang Q,Wang S,Zhou X,Li Y,Xing S,Sha Y,Yang F,Huang W,Liu N,Li Z,Chen Y,Xu Y,Zhu P,Lan F,Sun N
Mon Nov 21 00:00:00 EST 2022
PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis.
Scientific reports
Zhou M,Sun X,Wang C,Wang F,Fang C,Hu Z
Fri Jul 08 00:00:00 EDT 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 EDT 2022
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Cell reports
Wang W,Wu S,Cen Z,Zhang Y,Chen Y,Huang Y,Cillo AR,Prokopec JS,Quarato G,Vignali DAA,Stewart-Ornstein J,Li S,Lu B,Gong YN
Tue Nov 01 00:00:00 EDT 2022
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Journal of cellular physiology
Guo J,Nie J,Chen Z,Wang X,Hu H,Xu J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Oct 01 00:00:00 EDT 2022
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.
iScience
Magusto J,Beaupère C,Afonso MB,Auclair M,Delaunay JL,Soret PA,Courtois G,Aït-Slimane T,Housset C,Jéru I,Fève B,Ratziu V,Rodrigues CMP,Gautheron J
Fri Oct 21 00:00:00 EDT 2022
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Frontiers in oncology
Jiang X,Guo S,Xu M,Ma B,Liu R,Xu Y,Zhang Y
Wed Apr 13 00:00:00 EDT 2022
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Frontiers in pharmacology
Pan B,Xia Y,Fang S,Ai J,Wang K,Zhang J,Du C,Chen Y,Liu L,Yan S
Wed Nov 02 00:00:00 EDT 2022
MCPIP1 promotes cell proliferation, migration and angiogenesis of glioma via VEGFA-mediated ERK pathway.
Experimental cell research
Wang R,Sun S,Wang Z,Xu X,Jiang T,Liu H,Li X,Ren Z
Thu Sep 01 00:00:00 EDT 2022
Physiological and transcriptomic analyses reveal the toxicological mechanism and risk assessment of environmentally-relevant waterborne tetracycline exposure on the gills of tilapia (Oreochromis niloticus).
The Science of the total environment
Xu YC,Liu GH,Xu YH,Zhao T,Zheng H,Tan XY
Tue Feb 01 00:00:00 EST 2022
Characterization and function of mandarin fish c-Myc during viral infection process.
Fish & shellfish immunology
Ye C,Li N,Niu Y,Lin Q,Luo X,Liang H,Liu L,Fu X
Sat Jan 01 00:00:00 EST 2022
Early environmental enrichment for autism spectrum disorder Fmr1 mice models has positive behavioral and molecular effects.
Experimental neurology
Chen YS,Zhang SM,Yue CX,Xiang P,Li JQ,Wei Z,Xu L,Zeng Y
Wed Jun 01 00:00:00 EDT 2022
FTO promotes liver inflammation by suppressing m6A mRNA methylation of IL-17RA.
Frontiers in oncology
Gan X,Dai Z,Ge C,Yin H,Wang Y,Tan J,Sun S,Zhou W,Yuan S,Yang F
Fri Sep 30 00:00:00 EDT 2022
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.
International immunopharmacology
Li WQ,Qin ZS,Chen S,Cheng D,Yang SC,Choi YMM,Chu B,Zhou WH,Zhang ZJ
Thu Sep 01 00:00:00 EDT 2022
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.
Bioactive materials
Li Y,Yang L,Hou Y,Zhang Z,Chen M,Wang M,Liu J,Wang J,Zhao Z,Xie C,Lu X
Thu Dec 01 00:00:00 EST 2022
Cryo-EM structure of mouse TRPML2 in lipid nanodiscs.
The Journal of biological chemistry
Song X,Li J,Tian M,Zhu H,Hu X,Zhang Y,Cao Y,Ye H,McCormick PJ,Zeng B,Fu Y,Duan J,Zhang J
Tue Feb 01 00:00:00 EST 2022
Construction and osteogenic effects of 3D-printed porous titanium alloy loaded with VEGF/BMP-2 shell-core microspheres in a sustained-release system.
Frontiers in bioengineering and biotechnology
Liu Z,Xu Z,Wang X,Zhang Y,Wu Y,Jiang D,Jia R
Tue Nov 08 00:00:00 EST 2022
B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury.
The international journal of biochemistry & cell biology
Li GX,Jiang XH,Zang JN,Zhu BZ,Jia CC,Niu KW,Liu X,Jiang R,Wang B
Tue Nov 01 00:00:00 EDT 2022
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Frontiers in pharmacology
Liu M,Peng Y,Che Y,Zhou M,Bai Y,Tang W,Huang S,Zhang B,Deng S,Wang C,Yu Z
Tue Sep 13 00:00:00 EDT 2022
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Cancer cell international
Zhang Y,Sun M,Gao L,Liang X,Ma C,Lu J,Yue X
Sat Feb 12 00:00:00 EST 2022
EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway.
Glia
Liu C,Han S,Zheng J,Wang H,Li S,Li J
Sat Oct 01 00:00:00 EDT 2022
Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice.
Blood advances
Woloshun RR,Yu Y,Xu X,Lee JK,Zhu S,Shine JS,Ebea P,Stevens BR,Vidyasagar S,Collins JF
Tue May 24 00:00:00 EDT 2022
Small immune effectors coordinate peptidoglycan-derived immunity to regulate intestinal bacteria in shrimp.
PLoS pathogens
Liu PP,Wei Z,Cheng ZH,Wang XW
Tue Nov 01 00:00:00 EDT 2022
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
European journal of pharmacology
Hu P,Xu Y,Jiang Y,Huang J,Liu Y,Wang D,Tao T,Sun Z,Liu Y
Fri Aug 05 00:00:00 EDT 2022
The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.
Cellular oncology (Dordrecht)
Liu G,Yang ZF,Sun J,Sun BY,Zhou PY,Zhou C,Guan RY,Wang ZT,Yi Y,Qiu SJ
Thu Dec 01 00:00:00 EST 2022
Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associated protein 1 activity.
Experimental animals
Han N,Su Y,Guo M,Yu L
Fri Aug 05 00:00:00 EDT 2022
Human chorion-derived mesenchymal stem cells suppress JAK2/STAT3 signaling and induce apoptosis of cholangiocarcinoma cell lines.
Scientific reports
Jantalika T,Manochantr S,Kheolamai P,Tantikanlayaporn D,Saijuntha W,Pinlaor S,Chairoungdua A,Paraoan L,Tantrawatpan C
Tue Jul 05 00:00:00 EDT 2022
RNA 2'-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.
Frontiers in immunology
Li P,Liu Y,Song R,Zhao L,Yang J,Lu F,Cao X
Tue Apr 26 00:00:00 EDT 2022
DDIT3/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPKα-SIRT1 pathway.
Biochimica et biophysica acta. Molecular cell research
Yu X,Xu X,Dong W,Yang C,Luo Y,He Y,Jiang C,Wu Y,Wang J
Mon Aug 01 00:00:00 EDT 2022
Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders.
Frontiers in neuroscience
Shui M,Sun Y,Lin D,Xue Z,Liu J,Wu A,Wei C
Sat Apr 02 00:00:00 EDT 2022
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
Frontiers in oncology
Han T,Tong J,Wang M,Gan Y,Gao B,Chen J,Liu Y,Hao Q,Zhou X
Sat Jul 16 00:00:00 EDT 2022
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.
Cellular oncology (Dordrecht)
Sun J,Wang X,Shen Q,Wang M,Chen S,Zhang X,Huang Y,Zhang Z,Li W,Yuan Y,Huang Z
Thu Dec 01 00:00:00 EST 2022
Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.
Frontiers in pharmacology
Liu J,Zhang L,Wang Z,Chen S,Feng S,He Y,Zhang S
Sat Jul 16 00:00:00 EDT 2022
Role of notch signaling pathway in Muc5ac secretion induced by atmospheric PM2.5 in rats.
Ecotoxicology and environmental safety
Liu Y,Zhou L,Wu H,Wang Y,Zhang B
Sat Jan 01 00:00:00 EST 2022
The tyrosine phosphorylation of GRK2 is responsible for activated D2R-mediated insulin resistance.
Biochemical and biophysical research communications
Gao Z,Min X,Kim KM,Liu H,Hu L,Wu C,Zhang X
Sat Nov 05 00:00:00 EDT 2022
Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nature communications
Ji W,Peng Q,Fang X,Li Z,Li Y,Xu C,Zhao S,Li J,Chen R,Mo G,Wei Z,Xu Y,Li B,Zhang S
Fri Mar 18 00:00:00 EDT 2022
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
PPAR research
Qi S,Yan Q,Wang Z,Liu D,Zhan M,Du J,Chen L
Fri Apr 01 00:00:00 EDT 2022
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Environmental toxicology
Jin X,Yu W,Ye P
Fri Apr 01 00:00:00 EDT 2022
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Biomaterials science
Wang X,Tang X,Li N,Sun Y,Yu R,Zhang J,Li D,Yang B,Sun H
Tue Dec 20 00:00:00 EST 2022
Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.
Virulence
Yu J,Zhang W,Huo W,Meng X,Zhong T,Su Y,Liu Y,Liu J,Wang Z,Song F,Zhang S,Li Z,Yu X,Yu X,Hua S
Thu Dec 01 00:00:00 EST 2022
Modular assembly of the principal microtubule nucleator γ-TuRC.
Nature communications
Würtz M,Zupa E,Atorino ES,Neuner A,Böhler A,Rahadian AS,Vermeulen BJA,Tonon G,Eustermann S,Schiebel E,Pfeffer S
Tue Jan 25 00:00:00 EST 2022
Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Journal of inflammation research
Li B,Yang X,Zhang P,Guo J,Rong K,Wang X,Cao X,Zhou T,Zhao J
Sat Oct 15 00:00:00 EDT 2022
Identification of RPS7 as the Biomarker of Ferroptosis in Acute Kidney Injury.
BioMed research international
Zhang H,Liu X,Zhou L,Deng Z,Wang Y
Tue Oct 25 00:00:00 EDT 2022
Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice.
Journal of Cancer
Wang F,Cai K,Xiao Q,He L,Xie L,Liu Z
Tue Jan 04 00:00:00 EST 2022
Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Hu J,Cheng Y,Chen P,Huang Z,Yang L
Wed Jun 01 00:00:00 EDT 2022
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
PLoS genetics
Yamada S,Mizukoshi T,Tokunaga A,Sakakibara SI
Sat Oct 01 00:00:00 EDT 2022
Anti-Tumor Role of CAMK2B in Remodeling the Stromal Microenvironment and Inhibiting Proliferation in Papillary Renal Cell Carcinoma.
Frontiers in oncology
Jia Q,Liao X,Zhang Y,Xu B,Song Y,Bian G,Fu X
Tue Feb 08 00:00:00 EST 2022
ZIP1+ fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn2+ transfer.
Nature communications
Ni C,Lou X,Yao X,Wang L,Wan J,Duan X,Liang J,Zhang K,Yang Y,Zhang L,Sun C,Li Z,Wang M,Zhu L,Lv D,Qin Z
Fri Oct 07 00:00:00 EDT 2022
LincRNA-p21 Upregulates Nuclear Orphan Receptor Nr4a2 and Aggravates Myocardial Ischemia/Reperfusion Injury via Targeting MiR-466i-5p.
International heart journal
Zhai X,Liu R,Li J,Wang F,Liu L,Wei S,Bian Y,Pang J,Xue M,Qin D,Wang S,Xu T,Xu F,Cao S,Yuan Q,Chen Y
Tue Oct 04 00:00:00 EDT 2022
The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN.
Inflammopharmacology
Bu Y,Wu H,Deng R,Wang Y
Wed Jun 01 00:00:00 EDT 2022
Ligature induced periodontitis in rats causes gut dysbiosis leading to hepatic injury through SCD1/AMPK signalling pathway.
Life sciences
Xing T,Liu Y,Cheng H,Bai M,Chen J,Ji H,He M,Chen K
Sat Jan 01 00:00:00 EST 2022
The Construction and Immunogenicity Analyses of Recombinant Pseudorabies Virus With NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus-Like Particles Co-expression.
Frontiers in microbiology
Zhao J,Zhu L,Xu L,Li F,Deng H,Huang Y,Gu S,Sun X,Zhou Y,Xu Z
Tue Mar 22 00:00:00 EDT 2022
USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α.
Journal of cellular physiology
Huang W,Liu X,Zhang Y,Deng M,Li G,Chen G,Yu L,Jin L,Liu T,Wang Y,Chen Y
Fri Apr 01 00:00:00 EDT 2022
Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.
Cytokine
MacMullan MA,Wang P,Graham NA
Thu Sep 01 00:00:00 EDT 2022
Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Toxicology letters
Zhong Y,Zhang ZH,Wang JY,Xing Y,Ri MH,Jin HL,Zuo HX,Li MY,Ma J,Jin X
Tue Mar 01 00:00:00 EST 2022
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop.
International journal of biological sciences
Zhou C,He X,Tong C,Li H,Xie C,Wu Y,Wang L,Yan X,Luo D,Tang Y,Cheng Z,Xiong X
Fri Apr 15 00:00:00 EDT 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 EDT 2022
Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells.
Cell cycle (Georgetown, Tex.)
Huang M,Hua X,Xu J,Tian Z,Wang J,Chen H,Wang X,Shu P,Ye H,Shu J,Huang C
Sun May 15 00:00:00 EDT 2022
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Frontiers in oncology
Li L,Chen C,Xiang Q,Fan S,Xiao T,Chen Y,Zheng D
Wed Apr 13 00:00:00 EDT 2022
Molecular Mechanisms Underlying the Inhibition of Proliferation and Differentiation by Florfenicol in P19 Stem Cells: Transcriptome Analysis.
Frontiers in pharmacology
Hu D,Zhang B,Suo Y,Li Z,Wan Z,Zhao W,Chen L,Yin Z,Ning H,Ge Y,Li W
Sat Apr 23 00:00:00 EDT 2022
Circular RNA circASPM promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-130b-3p/E2F1 axis.
Journal of Cancer
Hou D,Wang Z,Li H,Liu J,Liu Y,Jiang Y,Lou M
Tue Apr 05 00:00:00 EDT 2022
All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice.
Virology journal
Niu X,Wang H,Zhao L,Lian P,Bai Y,Li J,Qiao J
Tue Jun 28 00:00:00 EDT 2022
Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection.
Frontiers in cardiovascular medicine
Yang H,Yang F,Luo M,Chen Q,Liu X,Zhang Y,Zhu G,Chen W,Li T,Shu C,Zhou Z
Mon May 02 00:00:00 EDT 2022
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation.
Cell death & disease
Su H,Meng C,Xu J,Su Z,Xiao C,Yang D
Fri Oct 21 00:00:00 EDT 2022
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Journal of ethnopharmacology
Xu LT,Wang T,Fang KL,Zhao Y,Wang XN,Ren DM,Shen T
Sun Jan 30 00:00:00 EST 2022
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Carbohydrate polymers
Li L,Xu W,Luo Y,Lao C,Tong X,Du J,Huang B,Li D,Chen J,Ye H,Cong F,Guo X,Li J
Thu Dec 01 00:00:00 EST 2022
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Nature cancer
Zhang T,Sun L,Hao Y,Suo C,Shen S,Wei H,Ma W,Zhang P,Wang T,Gu X,Li ST,Chen Z,Yan R,Zhang Y,Cai Y,Zhou R,Jia W,Huang F,Gao P,Zhang H
Sat Jan 01 00:00:00 EST 2022
Rare variants in GABRG2 associated with sleep-related hypermotor epilepsy.
Journal of neurology
Jiang YL,Song CG,Zhou HM,Feng B,Zhao JJ,Liu Y,Man YL,Han J,Liu SB,Jiang W
Thu Sep 01 00:00:00 EDT 2022
Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.
Dose-response : a publication of International Hormesis Society
Liu HX,Lu X,Zhao H,Li S,Gao L,Tian M,Liu QJ
Mon May 02 00:00:00 EDT 2022
The transcription factor TOX is involved in the regulation of T-cell exhaustion in neuroblastoma.
Immunology letters
Pei M,Chai W,Wang X,Duan Y,Wang H,Xi Y,Mou W,Wang W,Chen X,Zhang H,Li Q,Song W,Wang H,Ma X,Gui J
Mon Aug 01 00:00:00 EDT 2022
Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.
Cells
Huang J,Chen B,Wang H,Hu S,Yu X,Reilly J,He Z,You Y,Shu X
Tue Nov 22 00:00:00 EST 2022
Sulfate oligosaccharide of Gracilaria lemaneiformis modulates type 1 immunity by restraining T cell activation.
Carbohydrate polymers
Liu Q,Zhou Y,Ma L,Gu F,Liao K,Liu Y,Zhang Y,Liu H,Hong Y,Cao M,Liu WH,Liu C,Liu G
Fri Jul 15 00:00:00 EDT 2022
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Cells
He D,Liu Y,Li J,Wang H,Ye B,He Y,Li Z,Gao X,Fu S,Liu D
Mon Sep 19 00:00:00 EDT 2022
Quercetin Administration Following Hypoxia-Induced Neonatal Brain Damage Attenuates Later-Life Seizure Susceptibility and Anxiety-Related Behavior: Modulating Inflammatory Response.
Frontiers in pediatrics
Wu Y,Wei H,Li P,Zhao H,Li R,Yang F
Mon May 02 00:00:00 EDT 2022
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response.
Pharmaceutical biology
Shen Q,Chen Q,Liu Y,Xue X,Shen X,He Q,Wang G,Han F
Thu Dec 01 00:00:00 EST 2022
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Journal of cellular and molecular medicine
Xiao H,Peng L,Jiang D,Liu Y,Zhu L,Li Z,Geng J,Xie B,Huang X,Wang J,Dai H,Wang C
Tue Nov 01 00:00:00 EDT 2022
Divergence of Tbx4 hindlimb enhancer HLEA underlies the hindlimb loss during cetacean evolution.
Genomics
Liang N,Deme L,Kong Q,Sun L,Cao Y,Wu T,Huang X,Xu S,Yang G
Tue Mar 01 00:00:00 EST 2022
Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish.
Glycoconjugate journal
Ikeda A,Yamasaki C,Kubo Y,Doi Y,Komamizu M,Komatsu M,Shiozaki K
Mon Aug 01 00:00:00 EDT 2022
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain.
Journal of neuroinflammation
Peng Z,Peng S,Lin K,Zhao B,Wei L,Tuo Q,Liao D,Yuan T,Shi Z
Thu Jul 14 00:00:00 EDT 2022
Andrographolide suppresses breast cancer progression by modulating tumor-associated macrophage polarization through the Wnt/β-catenin pathway.
Phytotherapy research : PTR
Li L,Yang LL,Yang SL,Wang RQ,Gao H,Lin ZY,Zhao YY,Tang WW,Han R,Wang WJ,Liu P,Hou ZL,Meng MY,Liao LW
Thu Dec 01 00:00:00 EST 2022
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
Pharmaceutical research
Yadav A,Alnakhli A,Vemana HP,Bhutkar S,Muth A,Dukhande VV
Tue Nov 01 00:00:00 EDT 2022
Nonstructural Protein 1 of Variant PEDV Plays a Key Role in Escaping Replication Restriction by Complement C3.
Journal of virology
Fan B,Peng Q,Song S,Shi D,Zhang X,Guo W,Li Y,Zhou J,Zhu X,Zhao Y,Guo R,He K,Fan H,Ding S,Li B
Wed Sep 28 00:00:00 EDT 2022
Diallyl trisulfide sensitizes radiation therapy on glioblastoma through directly targeting thioredoxin 1.
Free radical biology & medicine
Tian Y,Ge Z,Xu M,Ge X,Zhao M,Ding F,Yin J,Wang X,You Y,Shi Z,Qian X
Sat Aug 20 00:00:00 EDT 2022
Elucidating the Potential Mechanisms Underlying Distraction Spinal Cord Injury-Associated Neuroinflammation and Apoptosis.
Frontiers in cell and developmental biology
Han B,Liang W,Hai Y,Liu Y,Chen Y,Ding H,Yang J,Yin P
Fri Mar 11 00:00:00 EST 2022
Overexpression of Lin28a induces a primary ovarian insufficiency phenotype via facilitation of primordial follicle activation in mice.
Molecular and cellular endocrinology
Chen J,Liu W,Lee KF,Liu K,Wong BPC,Shu-Biu Yeung W
Sat Jan 01 00:00:00 EST 2022
Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity.
Nature cancer
Tian L,Xu B,Chen Y,Li Z,Wang J,Zhang J,Ma R,Cao S,Hu W,Chiocca EA,Kaur B,Caligiuri MA,Yu J
Tue Nov 01 00:00:00 EDT 2022
Mesenchymal stem cell-exosome-mediated matrix metalloproteinase 1 participates in oral leukoplakia and carcinogenesis by inducing angiogenesis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Li S,Han Y,Lu M,Liu Z,Jin J,Guo Q,Wang Y,Liu H
Mon Aug 01 00:00:00 EDT 2022
Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.
Annals of the New York Academy of Sciences
Jia S,Zhang Q,Wang Y,Wei X,Gu H,Liu D,Ma W,He Y,Luo W,Yuan Z
Sat Oct 01 00:00:00 EDT 2022
Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.
Frontiers in cardiovascular medicine
Cui WW,Ye C,Wang KX,Yang X,Zhu PY,Hu K,Lan T,Huang LY,Wang W,Gu B,Yan C,Ma P,Qi SH,Luo L
Sat May 07 00:00:00 EDT 2022
Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis.
eLife
Li T,Cheng Q,Wang S,Ma C
Thu Sep 29 00:00:00 EDT 2022
Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway.
Frontiers in pharmacology
Zhang N,Guan C,Liu Z,Li C,Yang C,Xu L,Niu M,Zhao L,Zhou B,Che L,Wang Y,Xu Y
Tue Oct 25 00:00:00 EDT 2022
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Frontiers in cell and developmental biology
Sun S,Han Y,Zhang C,Liu H,Wang B,Cao S,Yuan Q,Wei S,Chen Y
Wed Mar 16 00:00:00 EDT 2022
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Investigative ophthalmology & visual science
Wu W,Su Y,Hu C,Tao H,Jiang Y,Zhu G,Zhu J,Zhai Y,Qu J,Zhou X,Zhao F
Fri Jul 08 00:00:00 EDT 2022
Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model.
Experimental and therapeutic medicine
Ruan Y,Ding Y,Li X,Zhang C,Wang M,Liu M,Wang L,Xing J,Hu L,Zhao X,Ding Z,Dong J,Liu Y
Sun May 01 00:00:00 EDT 2022
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.
Nature communications
Gruszczyk J,Grandvuillemin L,Lai-Kee-Him J,Paloni M,Savva CG,Germain P,Grimaldi M,Boulahtouf A,Kwong HS,Bous J,Ancelin A,Bechara C,Barducci A,Balaguer P,Bourguet W
Wed Nov 16 00:00:00 EST 2022
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Cancers
Zheng Y,Dai M,Dong Y,Yu H,Liu T,Feng X,Yu B,Zhang H,Wu J,Kong W,Yu X,Wu H
Thu Jul 14 00:00:00 EDT 2022
Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study.
Toxins
Saha P,Upright M,Bose D,Roy S,Trivedi A,More M,Scott GI,Brooks BW,Chatterjee S
Thu Dec 01 00:00:00 EST 2022
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xu W,Du X,Li J,Zhang Z,Ma X,Luo D,Xiao M,Sun Q
Sun May 01 00:00:00 EDT 2022
Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients.
Frontiers in genetics
Jiao M,Sun W,Li L,Li C,Zhou J,Li Q,Duan L
Wed Oct 19 00:00:00 EDT 2022
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Reproductive biology and endocrinology : RB&E
Wang P,Zhang S,Lin S,Lv Z
Fri Aug 12 00:00:00 EDT 2022
Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells.
Microbiology spectrum
Ye C,Liu S,Li N,Zuo S,Niu Y,Lin Q,Liang H,Luo X,Fu X
Wed Apr 27 00:00:00 EDT 2022
Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Journal of molecular medicine (Berlin, Germany)
Wang Y,Ma L,Jia S,Liu D,Gu H,Wei X,Ma W,Luo W,Bai Y,Wang W,Yuan Z
Thu Sep 01 00:00:00 EDT 2022
(-)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration.
Frontiers in medicine
Peng M,Zhou X,Yao F,Li H,Song W,Xiong S,Xia X
Sat Jul 16 00:00:00 EDT 2022
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Photodermatology, photoimmunology & photomedicine
Wang J,Wang Q,Chen P,Li Q,Li Z,Xu M,Zeng K,Li C
Fri Jul 01 00:00:00 EDT 2022
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
Cell death & disease
Zhao Y,Song J,Dong W,Liu X,Yang C,Wang D,Xue Y,Ruan X,Liu L,Wang P,Zhang M,Liu Y
Mon Sep 05 00:00:00 EDT 2022
Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli.
Frontiers in cellular and infection microbiology
Yao R,Mao X,Xu Y,Qiu X,Zhou L,Wang Y,Pang B,Chen M,Cao S,Bao L,Bao Y,Guo S,Hu L,Zhang H,Cui X
Fri Dec 16 00:00:00 EST 2022
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway.
Acta pharmacologica Sinica
Zhan LF,Zhang Q,Zhao L,Dong X,Pei XY,Peng LL,Zhang XW,Meng B,Shang WD,Pan ZW,Xu CQ,Lu YJ,Zhang MY
Wed Jun 01 00:00:00 EDT 2022
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis.
JCI insight
Lane BM,Chryst-Stangl M,Wu G,Shalaby M,El Desoky S,Middleton CC,Huggins K,Sood A,Ochoa A,Malone AF,Vancini R,Miller SE,Hall G,Kim SY,Howell DN,Kari JA,Gbadegesin R
Tue Jan 25 00:00:00 EST 2022
PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer.
Cancers
Wang T,Tang T,Jiang Y,He T,Qi L,Chang H,Qiao Y,Sun M,Shan C,Zhu X,Liu J,Wang J
Mon Jul 11 00:00:00 EDT 2022
A novel oncogenic seRNA promotes nasopharyngeal carcinoma metastasis.
Cell death & disease
Tan Y,Jiang C,Jia Q,Wang J,Huang G,Tang F
Sat Apr 23 00:00:00 EDT 2022
Expression and significance of let-7a and tumor necrosis factor-alpha in placenta of severe preeclampsia.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Zhou T,Wang W,Qi T,Ma S,Lu W
Thu Dec 01 00:00:00 EST 2022
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Antioxidants (Basel, Switzerland)
Zhang ZH,Cao XC,Peng JY,Huang SL,Chen C,Jia SZ,Ni JZ,Song GL
Sun Apr 24 00:00:00 EDT 2022
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Journal of ethnopharmacology
Xie CF,Feng KL,Wang JN,Luo R,Fang CK,Zhang Y,Shen CP,Zhong C
Wed Aug 10 00:00:00 EDT 2022
PEDF inhibits non‑small cell lung cancer proliferation by suppressing autophagy through downregulation of AMPK‑ULK1 signaling.
Oncology reports
Miao H,Hui H,Li H,Lin Y,Li D,Luo M,Jiang B,Zhang Y
Thu Dec 01 00:00:00 EST 2022
Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia-Reperfusion Injury via the PERK-ATF4-CHOP Pathway.
International journal of molecular sciences
Wu Y,Fan X,Chen S,Deng L,Jiang L,Yang S,Dong Z
Thu Dec 29 00:00:00 EST 2022
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.
Journal of translational medicine
Li X,Lu L,Hou W,Wang F,Huang T,Meng Z,Zhu M
Tue Mar 29 00:00:00 EDT 2022
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Investigative ophthalmology & visual science
Mu N,Wang H,Chen D,Wang F,Ji L,Zhang C,Li M,Lu P
Mon Jan 03 00:00:00 EST 2022
Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway.
Bioengineered
Wang P,Huang Y,Xia X,Han J,Zhang L,Zhao W
Tue Feb 01 00:00:00 EST 2022
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
The European respiratory journal
Song S,Fu Z,Guan R,Zhao J,Yang P,Li Y,Yin H,Lai Y,Gong G,Zhao S,Yu J,Peng X,He Y,Luo Y,Zhong N,Su J
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis.
Cell reports
Bajaj R,Rodriguez BL,Russell WK,Warner AN,Diao L,Wang J,Raso MG,Lu W,Khan K,Solis LS,Batra H,Tang X,Fradette JF,Kundu ST,Gibbons DL
Tue Sep 27 00:00:00 EDT 2022
Genome-Wide Analysis of Circular RNAs Reveals circCHRNG Regulates Sheep Myoblast Proliferation via miR-133/SRF and MEF2A Axis.
International journal of molecular sciences
Liu Y,Chen Q,Bao J,Pu Y,Han J,Zhao H,Ma Y,Zhao Q
Fri Dec 16 00:00:00 EST 2022
Microglial activation in the motor cortex mediated NLRP3-related neuroinflammation and neuronal damage following spinal cord injury.
Frontiers in cellular neuroscience
Hu X,Zhang Y,Wang L,Ding J,Li M,Li H,Wu L,Zeng Z,Xia H
Tue Nov 08 00:00:00 EST 2022
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
iScience
Dong X,Jiang D,Wang L,Zhao J,Yu L,Huang Y,Wu X,Zhu Y,Zhao Y,Zhao Q,Zhang G,Li X
Fri Apr 15 00:00:00 EDT 2022
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling.
Fish & shellfish immunology
Li S,Wang Y,Yu D,Zhang Y,Wang X,Shi M,Xiao Y,Li X,Xiao H,Chen L,Xiong X
Sat Oct 01 00:00:00 EDT 2022
Ginsenoside compound K acts via LRP1 to alleviate Amyloid β42-induced neuroinflammation in microglia by suppressing NF-κB.
Biochemical and biophysical research communications
Jiao H,Jia J
Sat Jan 29 00:00:00 EST 2022
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Cell
Karki R,Sharma BR,Tuladhar S,Williams EP,Zalduondo L,Samir P,Zheng M,Sundaram B,Banoth B,Malireddi RKS,Schreiner P,Neale G,Vogel P,Webby R,Jonsson CB,Kanneganti TD
Thu Jan 07 00:00:00 EST 2021
MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.
Gastroenterology
Lu Y,Li Y,Liu Q,Tian N,Du P,Zhu F,Han Y,Liu X,Liu X,Peng X,Wang X,Wu Y,Tong L,Li Y,Zhu Y,Wu L,Zhang P,Xu Y,Chen H,Li B,Tong X
Sun Aug 01 00:00:00 EDT 2021
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.
The Journal of experimental medicine
Ma S,Yan J,Barr T,Zhang J,Chen Z,Wang LS,Sun JC,Chen J,Caligiuri MA,Yu J
Mon Aug 02 00:00:00 EDT 2021
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
The Journal of experimental medicine
Ma L,Yu L,Jiang BC,Wang J,Guo X,Huang Y,Ren J,Sun N,Gao DS,Ding H,Lu J,Zhou H,Zou L,Gao Y,Wang L,Sun K,Ming Y,Meng Z,Tao YX,Yan M
Mon Dec 06 00:00:00 EST 2021
Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner.
Arthritis & rheumatology (Hoboken, N.J.)
Biswas C,Chu N,Burn TN,Kreiger PA,Behrens EM
Sat May 01 00:00:00 EDT 2021
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition.
Developmental cell
Price CJ,Stavish D,Gokhale PJ,Stevenson BA,Sargeant S,Lacey J,Rodriguez TA,Barbaric I
Mon Sep 13 00:00:00 EDT 2021
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics.
Neuro-oncology
Wang W,Marín-Ramos NI,He H,Zeng S,Cho HY,Swenson SD,Zheng L,Epstein AL,Schönthal AH,Hofman FM,Chen L,Chen TC
Sat Jan 30 00:00:00 EST 2021
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Hao F,Tian M,Zhang X,Jin X,Jiang Y,Sun X,Wang Y,Peng P,Liu J,Xia C,Feng Y,Wei M
Tue Jun 01 00:00:00 EDT 2021
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Cell death and differentiation
Chen X,Guan Y,Zhang Y,Jia Y,Li W,Guo C,Li Y,Wang X,Shi Y,Wang Q,Zhu F,Li Y,Zhang L
Thu Apr 01 00:00:00 EDT 2021
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.
EMBO reports
Xia TL,Li X,Wang X,Zhu YJ,Zhang H,Cheng W,Chen ML,Ye Y,Li Y,Zhang A,Dai DL,Zhu QY,Yuan L,Zheng J,Huang H,Chen SQ,Xiao ZW,Wang HB,Roy G,Zhong Q,Lin D,Zeng YX,Wang J,Zhao B,Gewurz BE,Chen J,Zuo Z,Zeng MS
Wed Apr 07 00:00:00 EDT 2021
D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Cell proliferation
Zhou X,Zheng Y,Sun W,Zhang Z,Liu J,Yang W,Yuan W,Yi Y,Wang J,Liu J
Mon Nov 01 00:00:00 EDT 2021
The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.
International journal of cancer
Roider T,Wang X,Hüttl K,Müller-Tidow C,Klapper W,Rosenwald A,Stewart JP,de Castro DG,Dreger P,Hermine O,Kluin-Nelemans HC,Grabe N,Dreyling M,Pott C,Ott G,Hoster E,Dietrich S
Fri Jan 01 00:00:00 EST 2021
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Oxidative medicine and cellular longevity
Su X,Yang Y,Guo C,Zhang R,Sun S,Wang Y,Qiao Q,Fu Y,Pang Q
Wed Jan 05 00:00:00 EST 2022
Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway.
Frontiers in cell and developmental biology
Wang J,Sun X,Wang X,Cui S,Liu R,Liu J,Fu B,Gong M,Wang C,Shi Y,Chen Q,Cai G,Chen X
Mon Sep 05 00:00:00 EDT 2022
Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis.
Frontiers in cell and developmental biology
Pang B,Zhu Z,Xiao C,Luo Y,Fang H,Bai Y,Sun Z,Ma J,Dang E,Wang G
Tue Feb 01 00:00:00 EST 2022
Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination.
Frontiers in cell and developmental biology
Sun X,Bai J,Xu J,Xi X,Gu M,Zhu C,Xue H,Chen C,Dong J
Tue Dec 21 00:00:00 EST 2021
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
Journal of leukocyte biology
Sun X,Liu M,Bai J,Xu J,Zhu C,Dong J,Chen C
Wed Dec 01 00:00:00 EST 2021
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Archives of pharmacal research
Zhang Q,Shang MM,Ling QF,Wu XP,Liu CY
Sun Aug 01 00:00:00 EDT 2021
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
Archives of pharmacal research
Zhang Q,Shang MM,Ling QF,Wu XP,Liu CY
Sun Aug 01 00:00:00 EDT 2021
Phospholipid Phosphatase 4 as a Driver of Malignant Glioma and Pancreatic Adenocarcinoma.
Frontiers in oncology
Tian W,Wang P,Wang Z,Qi H,Dong J,Wang H
Sat Feb 19 00:00:00 EST 2022
Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death.
Frontiers in oncology
Liu WJ,Pan PY,Sun Y,Wang JB,Zhou H,Xie X,Duan ZY,Dong HY,Chen WN,Zhang LD,Wang C
Tue Feb 08 00:00:00 EST 2022
NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.
Frontiers in oncology
Yan Z,Qu J,Li Z,Yi J,Su Y,Lin Q,Yu G,Lin Z,Yin W,Lu F,Liu J
Sat Jul 24 00:00:00 EDT 2021
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Burns & trauma
Zhang J,Yang P,Liu D,Gao M,Wang J,Yu T,Zhang X,Liu Y
Wed Apr 27 00:00:00 EDT 2022
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model.
Journal of Zhejiang University. Science. B
Zhou X,Li JQ,Wei LJ,He MZ,Jia J,Zhang JY,Wang SS,Feng L
Fri Nov 19 00:00:00 EST 2021
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Journal of immunology (Baltimore, Md. : 1950)
Torres-Odio S,Lei Y,Gispert S,Maletzko A,Key J,Menissy SS,Wittig I,Auburger G,West AP
Thu Apr 15 00:00:00 EDT 2021
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Wang W,Qin Y,Song H,Wang L,Jia M,Zhao C,Gong M,Zhao W
Tue Jun 01 00:00:00 EDT 2021
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Chen L,Bai J,Peng D,Gao Y,Cai X,Zhang J,Tang S,Niu L,Sun Y,Lou F,Zhou H,Yin Q,Wang Z,Sun L,Du X,Xu Z,Wang H,Li Q,Wang H
Mon Mar 01 00:00:00 EST 2021
NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.
Journal of cellular and molecular medicine
Hu B,Zhou S,Hu X,Zhang H,Lan X,Li M,Wang Y,Hu Q
Sun May 16 00:00:00 EDT 2021
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Journal of cellular and molecular medicine
Hu J,Wang J,Li C,Shang Y
Tue Jun 01 00:00:00 EDT 2021
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.
Journal of cell science
Yazlovitskaya EM,Plosa E,Bock F,Viquez OM,Mernaugh G,Gewin LS,De Arcangelis A,Georges-Labouesse E,Sonnenberg A,Blackwell TS,Pozzi A,Zent R
Wed Dec 15 00:00:00 EST 2021
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Biochimica et biophysica acta. Molecular cell research
Alavi MV
Mon Nov 01 00:00:00 EDT 2021
UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer.
Mediators of inflammation
Zhang R,Yang Y,Huang H,Li T,Ye L,Lin L,Wei Y
Thu Mar 31 00:00:00 EDT 2022
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Journal of oncology
Zhu Q,Yuan J,He Y,Hu Y
Wed Apr 27 00:00:00 EDT 2022
LncRNA TMEM220-AS1 suppresses hepatocellular carcinoma cell proliferation and invasion by regulating the TMEM220/β-catenin axis.
Journal of Cancer
Liu Y,Liu R,Zhao J,Zeng Z,Shi Z,Lu Q,Guo J,Li L,Yao Y,Liu X,Xu Q
Fri Oct 22 00:00:00 EDT 2021
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Saudi journal of biological sciences
Jiang W,Wan L,Chen P,Lu W
Wed Sep 01 00:00:00 EDT 2021
LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.
Annals of translational medicine
Pan S,Liu R,Wu X,Ma K,Luo W,Nie K,Zhang C,Meng X,Tong T,Chen X,Wang X,Deng M
Sat May 01 00:00:00 EDT 2021
Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway.
Molecular medicine reports
Zhao W,Wang Q
Wed Dec 01 00:00:00 EST 2021
Identification of KIF4A as a pan-cancer diagnostic and prognostic biomarker via bioinformatics analysis and validation in osteosarcoma cell lines.
PeerJ
Pan J,Lei X,Mao X
Sat Apr 23 00:00:00 EDT 2022
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Experimental and therapeutic medicine
Zhang L,Cao H,Tao H,Yang J,Gong W,Hu Q
Thu Jul 01 00:00:00 EDT 2021
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Cancer communications (London, England)
Wang JZ,Zhu W,Han J,Yang X,Zhou R,Lu HC,Yu H,Yuan WB,Li PC,Tao J,Lu Q,Wei JF,Yang H
Thu Jul 01 00:00:00 EDT 2021
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Cell death & disease
Li Y,Zhang N,Ma C,Xu W,Jin G,Zheng Y,Zhang L,Liu B,Gao C,Liu S
Tue Oct 26 00:00:00 EDT 2021
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner.
Molecular medicine reports
Wang WJ,Jiang X,Gao CC,Chen ZW
Wed Sep 01 00:00:00 EDT 2021
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Oxidative medicine and cellular longevity
Luo R,Li S,Li G,Lu S,Zhang W,Liu H,Lei J,Ma L,Ke W,Liao Z,Wang B,Song Y,Wang K,Zhang Y,Yang C
Wed Jan 05 00:00:00 EST 2022
Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXL.
Oncology letters
Pang X,Wang Y,Miao B,Fei S,Chen W
Mon Mar 01 00:00:00 EST 2021
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway.
Molecular medicine reports
Li A,Li S,Zhang C,Fang Z,Sun Y,Peng Y,Wang X,Zhang M
Wed Dec 01 00:00:00 EST 2021
A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
eLife
Hwang T,Parker SS,Hill SM,Ilunga MW,Grant RA,Mouneimne G,Keating AE
Thu Dec 02 00:00:00 EST 2021
Aerobic Exercise Improves Mitochondrial Function in Sarcopenia Mice Through Sestrin2 in an AMPKα2-Dependent Manner.
The journals of gerontology. Series A, Biological sciences and medical sciences
Liu S,Yu C,Xie L,Niu Y,Fu L
Mon Jun 14 00:00:00 EDT 2021
Autophagy promotes invadopodia formation in human ovarian cancer cells via the p62-extracellular signal-regulated kinase 1/2 pathway.
Experimental and therapeutic medicine
Zhou Z,Zhao J,Liu Y,Yan X,Sun H,Xia M,Su J
Wed Sep 01 00:00:00 EDT 2021
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Cancer letters
Zhang N,Hua X,Tu H,Li J,Zhang Z,Max C
Mon Nov 01 00:00:00 EDT 2021
Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li Y,Liu F,Zhang J,Liu X,Xiao P,Bai H,Chen S,Wang D,Sung SHP,Kwok RTK,Shen J,Zhu K,Tang BZ
Sat May 01 00:00:00 EDT 2021
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression.
Cell death & disease
Chu J,Tao L,Yao T,Chen Z,Lu X,Gao L,Fang L,Chen J,He G,Shen S,Zhang D
Thu Jan 21 00:00:00 EST 2021
LncIHAT Is Induced by Hypoxia-Inducible Factor 1 and Promotes Breast Cancer Progression.
Molecular cancer research : MCR
Chen L,Bao L,Niu Y,Wang JE,Kumar A,Xing C,Wang Y,Luo W
Thu Apr 01 00:00:00 EDT 2021
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Experimental eye research
Wu J,Wu T,Zheng S,Huang Y,Wang L
Wed Sep 01 00:00:00 EDT 2021
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways.
Frontiers in cellular and infection microbiology
Zhang W,Li Z,Yang H,Wang G,Liu G,Wang Y,Bello BK,Zhao P,Liang W,Dong J
Mon Oct 18 00:00:00 EDT 2021
CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway.
Journal of translational medicine
Wang Q,Xu J,Xiong Z,Xu T,Liu J,Liu Y,Chen J,Shi J,Shou Y,Yue C,Liu D,Liang H,Yang H,Yang X,Zhang X
Sat Oct 09 00:00:00 EDT 2021
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Journal of cellular and molecular medicine
Ma L,Li C,Lian S,Xu B,Lv H,Liu Y,Lu J,Ji H,Li S,Guo J,Yang H
Sun Aug 01 00:00:00 EDT 2021
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling.
Free radical biology & medicine
Wang Z,Wang L,Jiang R,Li C,Chen X,Xiao H,Hou J,Hu L,Huang C,Wang Y
Fri Oct 01 00:00:00 EDT 2021
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation.
Cancer medicine
Chu Q,Wang L,Zhang J,Wang W,Wang Y
Tue Jun 01 00:00:00 EDT 2021
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway.
BMC complementary medicine and therapies
Nie F,Yan J,Ling Y,Liu Z,Fu C,Li X,Qin Y
Sat Apr 10 00:00:00 EDT 2021
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Acta cirurgica brasileira
Xu J,Zhan T,Zheng W,Huang YK,Chen K,Zhang XH,Ren P,Huang X
Fri Jan 29 00:00:00 EST 2021
CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway.
Experimental and therapeutic medicine
Luo Y,Zheng D,Mou T,Pu J,Huang Z,Chen W,Zhang Y,Wu Z
Wed Dec 01 00:00:00 EST 2021
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
Genes
Su Z,Yang Y,Wang S,Zhao S,Zhao H,Li X,Niu Y,Qiu G,Wu Z,Wu N,Zhang TJ
Fri Nov 12 00:00:00 EST 2021
Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming.
Journal of Alzheimer's disease : JAD
Li W,Wang S,Zhang H,Li B,Xu L,Li Y,Kong C,Jiao H,Wang Y,Pang Y,Qin W,Jia L,Jia J
Tue Nov 23 00:00:00 EST 2021
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Cellular & molecular biology letters
Zhao M,Wang S,Zuo A,Zhang J,Wen W,Jiang W,Chen H,Liang D,Sun J,Wang M
Fri Sep 03 00:00:00 EDT 2021
Comparative Efficacy of Haizao Yuhu Decoction Composed of Different Varieties of Glycyrrhiza in Goiter Rats.
Evidence-based complementary and alternative medicine : eCAM
Chen F,Li N,Xiu L,Liu H,Chen S,He C,Fan A,Yu X,Wang X,Ge C,Huo M,He J,Zhong G
Wed Sep 29 00:00:00 EDT 2021
Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Bai ZM,Li XF,Yang Y,Yang YF,Lv DR,Tang LL
Wed Sep 01 00:00:00 EDT 2021
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
Cell death and differentiation
Zhang D,Ni N,Wang Y,Tang Z,Gao H,Ju Y,Sun N,He X,Gu P,Fan X
Fri Jan 01 00:00:00 EST 2021
Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sugiyama K,Kuroiwa M,Shuto T,Ohnishi YN,Kawahara Y,Miyamoto Y,Fukuda T,Nishi A
Wed Jul 28 00:00:00 EDT 2021
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
Placenta
Chen J,Liu J,Gao S,Qiu Y,Wang Y,Zhang Y,Gao L,Qi G,Wu Y,Lash GE,Li P
Fri Jan 01 00:00:00 EST 2021
Evaluation of Stable LifeAct-mRuby2- and LAMP1-NeonGreen Expressing A549 Cell Lines for Investigation of Aspergillus fumigatus Interaction with Pulmonary Cells.
International journal of molecular sciences
Schiefermeier-Mach N,Moresco V,Geley S,Heinrich L,Lechner L,Oberhauser H,Perkhofer S
Mon May 31 00:00:00 EDT 2021
β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer.
Frontiers in pharmacology
Hu J,Chen C,Lu R,Zhang Y,Wang Y,Hu Q,Li W,Wang S,Jing O,Yi H,Zhang W,Chen L,Huang W,Luo J,McLeod HL,Xu R,He Y
Tue Nov 02 00:00:00 EDT 2021
Deleterious impact of nerve growth factor precursor (proNGF) on bladder urothelial and smooth muscle cells.
Cellular signalling
Mossa AH,Abdaem J,Cammisotto P,Campeau L
Sat May 01 00:00:00 EDT 2021
Purification, structural characterization, and PCSK9 secretion inhibitory effect of the novel alkali-extracted polysaccharide from Cordyceps militaris.
International journal of biological macromolecules
Wang J,Wang Y,Yang X,Lin P,Liu N,Li X,Zhang B,Guo S
Sat May 15 00:00:00 EDT 2021
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Journal of neuroinflammation
Gao C,Jia W,Xu W,Wu Q,Wu J
Sat May 22 00:00:00 EDT 2021
Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Molecular human reproduction
Esfandyari S,Winston NJ,Fierro MA,Scoccia H,Stocco C
Sat May 29 00:00:00 EDT 2021
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Frontiers in oncology
Xia X,Zhang H,Xia P,Zhu Y,Liu J,Xu K,Yuan Y
Tue Apr 26 00:00:00 EDT 2022
Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.
Journal of ethnopharmacology
Zhang XJ,Shang K,Pu YK,Wang Q,Wang TT,Zou Y,Wang YM,Xu YJ,Li XL,Zhang RH,Xiao WL
Tue Oct 05 00:00:00 EDT 2021
Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy.
Chemico-biological interactions
Pei L,He L
Wed Aug 25 00:00:00 EDT 2021
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Molecules (Basel, Switzerland)
Dai Y,Sun X,Li B,Ma H,Wu P,Zhang Y,Zhu M,Li HM,Qin M,Wu CZ
Sun Mar 14 00:00:00 EST 2021
Mel1b and Mel1c melatonin receptors mediate green light-induced secretion of growth hormone in chick adenohypophysis cells via the AC/PKA and ERK1/2 signalling pathways.
Journal of photochemistry and photobiology. B, Biology
Liu X,Wang L,Wang Z,Dong Y,Chen Y,Cao J
Wed Dec 01 00:00:00 EST 2021
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
BMC cancer
Su X,Yang Y,Yang Q,Pang B,Sun S,Wang Y,Qiao Q,Guo C,Liu H,Pang Q
Fri Nov 05 00:00:00 EDT 2021
Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2.
Brain research
Guan Y,Wang J,Wu X,Song L,Wang Y,Gong M,Li B
Wed Dec 01 00:00:00 EST 2021
2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells.
Aging
Tan T,Fu X,Qu J,Zhang M,Chen H,Wang Y,Wang B,Li J,Liu J,Liu P
Sun Sep 12 00:00:00 EDT 2021
Myosin 1b promotes migration, invasion and glycolysis in cervical cancer via ERK/HIF-1α pathway.
American journal of translational research
Wen LJ,Hu XL,Li CY,Liu J,Li ZY,Li YZ,Zhou JY
Tue Dec 28 00:00:00 EST 2021
Plumbagin, a Biomolecule with (Anti)Osteoclastic Properties.
International journal of molecular sciences
Sultanli S,Ghumnani S,Ashma R,Kubatzky KF
Tue Mar 09 00:00:00 EST 2021
Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling.
Biomedicines
Chinnapaka S,Yang KS,Flowers Q,Faisal M,Nerone WV,Rubin JP,Ejaz A
Sat Nov 27 00:00:00 EST 2021
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Frontiers in pharmacology
Gong S,Ma H,Zheng F,Huang J,Zhang Y,Yu B,Li F,Kou J
Wed Dec 15 00:00:00 EST 2021
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
World journal of gastroenterology
Wang RT,Miao RC,Zhang X,Yang GH,Mu YP,Zhang ZY,Qu K,Liu C
Sun Feb 28 00:00:00 EST 2021
Overexpression of ICAT Inhibits the Progression of Colorectal Cancer by Binding with β-Catenin in the Cytoplasm.
Technology in cancer research & treatment
Hu J,Wang Z,Chen J,Yu Z,Zhang J,Li W,Lin M,Yang X,Liu H
Thu Feb 10 00:00:00 EST 2022
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Biochemical pharmacology
Li M,Chen X,Wang X,Wei X,Wang D,Liu X,Xu L,Batu W,Li Y,Guo B,Zhang L
Fri Oct 01 00:00:00 EDT 2021
The expression of IFN-β is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Virus research
Yang Z,Zheng H,Li H,Chen Y,Hou D,Fan Q,Song J,Guo L,Liu L
Fri Oct 15 00:00:00 EDT 2021
The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.
Life (Basel, Switzerland)
Liu FC,Yu HP,Liao CC,Chou AH,Lee HC
Fri Oct 15 00:00:00 EDT 2021
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
International journal of molecular sciences
Chen F,Jiao XF,Meng F,Wang YS,Ding ZM,Miao YL,Xiong JJ,Huo LJ
Mon May 03 00:00:00 EDT 2021
SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages.
International journal of biological sciences
Li S,Han S,Jin K,Yu T,Chen H,Zhou X,Tan Z,Zhang G
Mon Dec 20 00:00:00 EST 2021
Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma.
Frontiers in molecular biosciences
Li C,Zhang W,Fang T,Li N,Wang Y,He L,He H
Tue Dec 21 00:00:00 EST 2021
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Evidence-based complementary and alternative medicine : eCAM
Yang K,Wu K,Feng J,Yutian L,Zhu X,Xu D
Mon Apr 25 00:00:00 EDT 2022
Exosomes in ovarian cancer ascites promote epithelial-mesenchymal transition of ovarian cancer cells by delivery of miR-6780b-5p.
Cell death & disease
Cai J,Gong L,Li G,Guo J,Yi X,Wang Z
Wed Feb 24 00:00:00 EST 2021
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Free radical biology & medicine
Liao Y,Xu J,Qin B,Shi J,Qin C,Xie F,Ou S,Tang J,Wang W,Wu F,Bai L
Fri Aug 20 00:00:00 EDT 2021
The deubiquitylase USP9X controls ribosomal stalling.
The Journal of cell biology
Clancy A,Heride C,Pinto-Fernández A,Elcocks H,Kallinos A,Kayser-Bricker KJ,Wang W,Smith V,Davis S,Fessler S,McKinnon C,Katz M,Hammonds T,Jones NP,O'Connell J,Follows B,Mischke S,Caravella JA,Ioannidis S,Dinsmore C,Kim S,Behrens A,Komander D,Kessler BM,Urbé S,Clague MJ
Mon Mar 01 00:00:00 EST 2021
The deubiquitylase USP9X controls ribosomal stalling.
The Journal of cell biology
Clancy A,Heride C,Pinto-Fernández A,Elcocks H,Kallinos A,Kayser-Bricker KJ,Wang W,Smith V,Davis S,Fessler S,McKinnon C,Katz M,Hammonds T,Jones NP,O'Connell J,Follows B,Mischke S,Caravella JA,Ioannidis S,Dinsmore C,Kim S,Behrens A,Komander D,Kessler BM,Urbé S,Clague MJ
Mon Mar 01 00:00:00 EST 2021
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Frontiers in pharmacology
Chen W,Zhang J,Zhong W,Liu Y,Lu Y,Zeng Z,Huang H,Wan X,Meng X,Zou F,Cai S,Dong H
Tue Oct 05 00:00:00 EDT 2021
Neuropathy-associated histidyl-tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish.
The FEBS journal
Mullen P,Abbott JA,Wellman T,Aktar M,Fjeld C,Demeler B,Ebert AM,Francklyn CS
Fri Jan 01 00:00:00 EST 2021
Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
The Journal of biological chemistry
Zheng M,Karki R,Kancharana B,Berns H,Pruett-Miller SM,Kanneganti TD
Wed Dec 01 00:00:00 EST 2021
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Journal of experimental & clinical cancer research : CR
Wang Y,Zhang J,Li YJ,Yu NN,Liu WT,Liang JZ,Xu WW,Sun ZH,Li B,He QY
Fri Sep 24 00:00:00 EDT 2021
Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop.
Pharmacological research
Gu C,She X,Zhou C,Su T,He S,Meng C,Gu Q,Luo D,Zheng Z,Qiu Q
Wed Dec 01 00:00:00 EST 2021
REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Kim SM,Zhang S,Park J,Sung HJ,Tran TT,Chung C,Han IO
Fri Oct 01 00:00:00 EDT 2021
NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis.
Journal of periodontal research
Guo W,Zhao Y,Li H,Lei L
Tue Jun 01 00:00:00 EDT 2021
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
Environmental pollution (Barking, Essex : 1987)
Liu J,Li X,Zhou G,Zhang Y,Sang Y,Wang J,Li Y,Ge W,Sun Z,Zhou X
Wed Sep 01 00:00:00 EDT 2021
Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain.
Frontiers in pharmacology
Wang X,Zhang B,Li X,Liu X,Wang S,Xie Y,Pi J,Yang Z,Li J,Jia Q,Zhang Y
Tue Jan 04 00:00:00 EST 2022
Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis.
Cell death discovery
Feng YH,Li LF,Zhang Q,Zhang JH,Huang Y,Lv YL,Jia JZ,Zhang D,Hu JY,Huang YS
Thu Aug 12 00:00:00 EDT 2021
Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
Aging
Peng HH,Wu CY,Hsiao YC,Martel J,Ke PY,Chiu CY,Liau JC,Chang IT,Su YH,Ko YF,Young JD,Ojcius DM
Thu May 20 00:00:00 EDT 2021
Topotecan induces hepatocellular injury via ASCT2 mediated oxidative stress.
Gastroenterologia y hepatologia
Zhou G,Qin M,Zhang X,Yang J,Yu H
Fri Jan 01 00:00:00 EST 2021
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Stem cell research & therapy
Xun J,Li C,Liu M,Mei Y,Zhou Q,Wu B,Xie F,Liu Y,Dai R
Tue Jul 27 00:00:00 EDT 2021
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-¿B2 Signaling Pathway.
OncoTargets and therapy
Yuan J,Zhang Q,Wu S,Yan S,Zhao R,Sun Y,Tian X,Zhou K
Thu Apr 21 00:00:00 EDT 2022
Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Brain research bulletin
Zhang B,Han X,Gao Q,Liu J,Li S,Zha W,Wang X,Guo X,Gao D
Mon Feb 01 00:00:00 EST 2021
FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.
Cell biology international
Tang Y,Jiang L,Zhao X,Hu D,Zhao G,Luo S,Du X,Tang W
Wed Dec 01 00:00:00 EST 2021
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
Cell
Shen C,Li R,Negro R,Cheng J,Vora SM,Fu TM,Wang A,He K,Andreeva L,Gao P,Tian Z,Flavell RA,Zhu S,Wu H
Thu Nov 11 00:00:00 EST 2021
Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD.
Life sciences
Li H,Dun Y,Zhang W,You B,Liu Y,Fu S,Qiu L,Cheng J,Ripley-Gonzalez JW,Liu S
Sat May 15 00:00:00 EDT 2021
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Mediators of inflammation
Wang L,Li S,Qi L,Ling L
Thu Mar 31 00:00:00 EDT 2022
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Canadian journal of physiology and pharmacology
Ding F,Yang S
Wed Sep 01 00:00:00 EDT 2021
Binding of Benzo[a]pyrene Alters the Bioreactivity of Fine Biochar Particles toward Macrophages Leading to Deregulated Macrophagic Defense and Autophagy.
ACS nano
Ma J,Liu X,Yang Y,Qiu J,Dong Z,Ren Q,Zuo YY,Xia T,Chen W,Liu S
Tue Jun 22 00:00:00 EDT 2021
The imbalance of PGD2-DPs pathway is involved in the type 2 diabetes brain injury by regulating autophagy.
International journal of biological sciences
Yang Y,Xiang P,Chen Q,Luo Y,Wang H,Li H,Yang L,Hu C,Zhang J,Li Y,Xia H,Chen Z,Yang J
Fri Feb 18 00:00:00 EST 2022
AIF3 splicing switch triggers neurodegeneration.
Molecular neurodegeneration
Liu S,Zhou M,Ruan Z,Wang Y,Chang C,Sasaki M,Rajaram V,Lemoff A,Nambiar K,Wang JE,Hatanpaa KJ,Luo W,Dawson TM,Dawson VL,Wang Y
Wed Apr 14 00:00:00 EDT 2021
Chemical conjugation of FITC to track silica nanoparticles in vivo and in vitro: An emerging method to assess the reproductive toxicity of industrial nanomaterials.
Environment international
Li J,Tian J,Yin H,Peng Y,Liu S,Yao S,Zhang L
Thu Jul 01 00:00:00 EDT 2021
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Cell metabolism
Liu Y,Liang G,Xu H,Dong W,Dong Z,Qiu Z,Zhang Z,Li F,Huang Y,Li Y,Wu J,Yin S,Zhang Y,Guo P,Liu J,Xi JJ,Jiang P,Han D,Yang CG,Xu MM
Tue Jun 01 00:00:00 EDT 2021
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Cell death & disease
Chen T,Guo Y,Wang J,Ai L,Ma L,He W,Li Z,Yu X,Li J,Fan X,Gu Y,Liang H
Thu Jun 10 00:00:00 EDT 2021
[Effect of astragaloside IV on the expression of NOD-like receptor protein 3 inflammasome in neonatal rats with hypoxic-ischemic brain damage].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Li N,Mu YP,Liu CY,Wang Y,Li XF,Wang XW
Thu Apr 01 00:00:00 EDT 2021
TRIM21 negatively regulates Corynebacterium pseudotuberculosis-induced inflammation and is critical for the survival of C. pseudotuberculosis infected C57BL6 mice.
Veterinary microbiology
Tan J,Yi W,Wang Z,Ye C,Tian S,Li X,Zou A,Zhao X,Yuan Y,Wang X,Hu S,Zhou Z
Fri Oct 01 00:00:00 EDT 2021
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Balkan medical journal
Yuan K,Sun Y,Ji Y
Sat May 01 00:00:00 EDT 2021
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Molecular medicine (Cambridge, Mass.)
Zhou B,Zhou Y,Liu Y,Zhang H,Mao H,Peng M,Xu A,Li Z,Wang H,Tan H,Ren H,Zhou X,Long Y
Fri Aug 06 00:00:00 EDT 2021
MiR-100-5p regulates cardiac hypertrophy through activation of autophagy by targeting mTOR.
Human cell
Zeng J,Wang L,Zhao J,Zheng Z,Peng J,Zhang W,Wen T,Nie J,Ding L,Yi D
Wed Sep 01 00:00:00 EDT 2021
Improved BMP2-CPC-stimulated osteogenesis in vitro and in vivo via modulation of macrophage polarization.
Materials science & engineering. C, Materials for biological applications
Shen H,Shi J,Zhi Y,Yang X,Yuan Y,Si J,Shen SGF
Fri Jan 01 00:00:00 EST 2021
Disruption of Circadian Clocks Promotes Progression of Alzheimer's Disease in Diabetic Mice.
Molecular neurobiology
Huang J,Peng X,Fan R,Dong K,Shi X,Zhang S,Yu X,Yang Y
Wed Sep 01 00:00:00 EDT 2021
SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function.
Molecular neurobiology
Xu X,Cui Y,Li C,Wang Y,Cheng J,Chen S,Sun J,Ren J,Yao X,Gao J,Huang X,Wan Q,Wang Q
Fri Oct 01 00:00:00 EDT 2021
Targeting of glioma stem-like cells with a parthenolide derivative ACT001 through inhibition of AEBP1/PI3K/AKT signaling.
Theranostics
Hou Y,Sun B,Liu W,Yu B,Shi Q,Luo F,Bai Y,Feng H
Wed Aug 04 00:00:00 EDT 2021
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Proceedings of the National Academy of Sciences of the United States of America
Li G,Wu J,Li L,Jiang P
Tue Jul 13 00:00:00 EDT 2021
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.
Frontiers in oncology
Wang J,Li H,Wang L,Zhang J,Li M,Qiao L,Zhang J,Liu L,Zhang C,Gao J,Li W
Tue Sep 07 00:00:00 EDT 2021
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
International journal of biological sciences
Sun N,Meng F,Zhao J,Li X,Li R,Han J,Chen X,Cheng W,Yang X,Kou Y,Zheng K,Yang J,Ikezoe T
Thu Mar 24 00:00:00 EDT 2022
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Journal of medicinal chemistry
Xu C,Xiao Z,Wang J,Lai H,Zhang T,Guan Z,Xia M,Chen M,Ren L,He Y,Gao Y,Zhao C
Thu Sep 23 00:00:00 EDT 2021
Effects of Bacillus subtilis on jejunal integrity, redox status, and microbial composition of intrauterine growth restriction suckling piglets.
Journal of animal science
Yun Y,Ji S,Yu G,Jia P,Niu Y,Zhang H,Zhang X,Wang T,Zhang L
Fri Oct 01 00:00:00 EDT 2021
Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways.
Frontiers in pharmacology
Yang X,An X,Wang C,Gao F,Lin Y,Chen W,Deng Q,Xu D,Li S,Zhang P,Sun B,Hou Y,Wu J
Fri Nov 05 00:00:00 EDT 2021
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.
Frontiers in oncology
Tai YK,Chan KKW,Fong CHH,Ramanan S,Yap JLY,Yin JN,Yip YS,Tan WR,Koh APF,Tan NS,Chan CW,Huang RYJ,Li JZ,Fröhlich J,Franco-Obregón A
Sat Jul 16 00:00:00 EDT 2022
Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts.
International journal of biological sciences
Zhang Y,Liu Z,Wang K,Lu S,Fan S,Xu L,Cai B
Wed Mar 30 00:00:00 EDT 2022
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cai B,Liu M,Li J,Xu D,Li J
Thu Apr 01 00:00:00 EDT 2021
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Frontiers in medicine
Wang S,Zuo A,Jiang W,Xie J,Lin H,Sun W,Zhao M,Xia J,Shao J,Zhao X,Liang D,Yang A,Sun J,Wang M
Wed Feb 23 00:00:00 EST 2022
TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease.
Cell death & disease
Carlisle RE,Mohammed-Ali Z,Lu C,Yousof T,Tat V,Nademi S,MacDonald ME,Austin RC,Dickhout JG
Fri Oct 08 00:00:00 EDT 2021
Comparison of content-toxicity-activity of six ingenane-type diterpenoids between Euphorbia kansui before and after stir-fried with vinegar by using UFLC-MS/MS, zebrafish embryos and HT-29 cells.
Journal of pharmaceutical and biomedical analysis
Zhou SK,Zhang Y,Ju YH,Zhang Q,Luo D,Cao YD,Yao WF,Tang YP,Zhang L
Sat Feb 20 00:00:00 EST 2021
Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.
Arteriosclerosis, thrombosis, and vascular biology
Jiang Y,Liu H,Yu H,Zhou Y,Zhang J,Xin W,Li Y,He S,Ma C,Zheng X,Zhang L,Zhao X,Wu B,Jiang C,Zhu D
Wed May 05 00:00:00 EDT 2021
GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice.
Neurobiology of aging
Hu B,Geng C,Guo F,Liu Y,Zong YC,Hou XY
Wed Dec 01 00:00:00 EST 2021
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Frontiers in oncology
Qian XL,Zhou F,Xu S,Jiang J,Chen ZP,Wang SK,Zuo Y,Ni C
Sun May 23 00:00:00 EDT 2021
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Frontiers in immunology
Sui L,Zhao Y,Wang W,Wu P,Wang Z,Yu Y,Hou Z,Tan G,Liu Q
Tue Jun 15 00:00:00 EDT 2021
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling.
International immunopharmacology
Shentu Y,Li Y,Xie S,Jiang H,Sun S,Lin R,Chen C,Bai Y,Zhang Y,Zheng C,Zhou Y
Thu Apr 01 00:00:00 EDT 2021
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
Journal of chemical neuroanatomy
Zhang Y,Zhou L,Lian H,Zhang Y,Tong S,Wang Z
Mon Nov 01 00:00:00 EDT 2021
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
Hepatobiliary & pancreatic diseases international : HBPD INT
Pu JL,Huang ZT,Luo YH,Mou T,Li TT,Li ZT,Wei XF,Wu ZJ
Sun Aug 01 00:00:00 EDT 2021
Small molecule targeting topoisomerase 3β for cancer therapy.
Pharmacological research
Zhang X,Wang L,Zhang Q,Lyu S,Zhu D,Shen M,Ke X,Qu Y
Wed Dec 01 00:00:00 EST 2021
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells.
World journal of gastroenterology
Cui HY,Rong JS,Chen J,Guo J,Zhu JQ,Ruan M,Zuo RR,Zhang SS,Qi JM,Zhang BH
Tue Sep 28 00:00:00 EDT 2021
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.
Journal of natural medicines
An MF,Wang MY,Shen C,Sun ZR,Zhao YL,Wang XJ,Sheng J
Fri Jan 01 00:00:00 EST 2021
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.
Cellular & molecular immunology
Chen Y,He H,Lin B,Chen Y,Deng X,Jiang W,Zhou R
Tue Jun 01 00:00:00 EDT 2021
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
JCI insight
Devenport SN,Singhal R,Radyk MD,Taranto JG,Kerk SA,Chen B,Goyert JW,Jain C,Das NK,Oravecz-Wilson K,Zhang L,Greenson JK,Chen YE,Soleimanpour SA,Reddy P,Lyssiotis CA,Shah YM
Thu Jun 17 00:00:00 EDT 2021
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
Viruses
Su WQ,Yu XJ,Zhou CM
Thu Dec 09 00:00:00 EST 2021
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
Mon Dec 20 00:00:00 EST 2021
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT1A receptor: Insights from transcriptomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Qiao YL,Zhou JJ,Liang JH,Deng XP,Zhang ZJ,Huang HL,Li S,Dai SF,Liu CQ,Luan ZL,Yu ZL,Sun CP,Ma XC
Fri Jan 01 00:00:00 EST 2021
Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma.
Frontiers in oncology
Fu Y,Ding L,Yang X,Ding Z,Huang X,Zhang L,Chen S,Hu Q,Ni Y
Tue Mar 30 00:00:00 EDT 2021
Stigmasterol inhibits the progression of lung cancer by regulating retinoic acid-related orphan receptor C.
Histology and histopathology
Dong Y,Chen C,Chen C,Zhang C,Zhang L,Zhang Y,Li Y,Dong Z
Wed Dec 01 00:00:00 EST 2021
Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).
Virus research
Tang Z,Luo W,Huang Z,Yuan M,Wu W,Yang K
Fri Jul 02 00:00:00 EDT 2021
β-Conglycinin induces the formation of neutrophil extracellular traps dependent on NADPH oxidase-derived ROS, PAD4, ERK1/2 and p38 signaling pathways in mice.
Food & function
Liu X,Fu Y,Wang J,Wu D,Li S,Wang C,Yang Z,Zhou E
Thu Jan 07 00:00:00 EST 2021
The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.
Journal of experimental & clinical cancer research : CR
Qian W,Chen K,Qin T,Xiao Y,Li J,Yue Y,Zhou C,Ma J,Duan W,Lei J,Han L,Li L,Shen X,Wu Z,Ma Q,Wang Z
Sat Jan 09 00:00:00 EST 2021
Ultrathin 2D Titanium Carbide MXene (Ti3 C2 Tx ) Nanoflakes Activate WNT/HIF-1α-Mediated Metabolism Reprogramming for Periodontal Regeneration.
Advanced healthcare materials
Cui D,Kong N,Ding L,Guo Y,Yang W,Yan F
Mon Nov 01 00:00:00 EDT 2021
Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.
Frontiers in pharmacology
Lin L,An L,Chen H,Feng L,Lu M,Liu Y,Chu C,Shan J,Xie T,Wang X,Wang S
Tue Dec 21 00:00:00 EST 2021
Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice.
mSystems
Shi Z,Lei H,Chen G,Yuan P,Cao Z,Ser HL,Zhu X,Wu F,Liu C,Dong M,Song Y,Guo Y,Chen C,Hu K,Zhu Y,Zeng XA,Zhou J,Lu Y,Patterson AD,Zhang L
Tue Feb 23 00:00:00 EST 2021
SLC39A7 promotes malignant behaviors in glioma via the TNF-α-mediated NF-κB signaling pathway.
Journal of Cancer
Chen L,Zhou J,Li L,Zhao J,Li H,Zheng W,Xu J,Jing Z
Tue Sep 07 00:00:00 EDT 2021
IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.
Frontiers in cellular neuroscience
Chu B,Li M,Cao X,Li R,Jin S,Yang H,Xu L,Wang P,Bi J
Tue Apr 13 00:00:00 EDT 2021
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
Neuroscience bulletin
Wang T,Zhou M,Zhang Q,Zhang C,Peng G
Wed Dec 01 00:00:00 EST 2021
Gastrodin exerts protective effects in reactive TNC1 astrocytes via regulation of the Notch signaling pathway.
Annals of translational medicine
Zhang XLN,Yang XK,Wu CY,Yuan Y
Wed Dec 01 00:00:00 EST 2021
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Journal of agricultural and food chemistry
Sheng K,Xu Y,Kong X,Wang J,Zha X,Wang Y
Wed Dec 15 00:00:00 EST 2021
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.
Aging
Chen TT,Zhou X,Xu YN,Li Y,Wu XY,Xiang Q,Fu LY,Hu XX,Tao L,Shen XC
Wed Mar 10 00:00:00 EST 2021
Purified Vitexin Compound 1 Serves as a Promising Antineoplastic Agent in Ovarian Cancer.
Frontiers in oncology
Ma K,Wang K,Zhou Y,Liu N,Guo W,Qi J,Hu Z,Su S,Tang P,Zhou X
Tue Oct 12 00:00:00 EDT 2021
Spermidine Affects Cardiac Function in Heart Failure Mice by Influencing the Gut Microbiota and Cardiac Galectin-3.
Frontiers in cardiovascular medicine
Chen Y,Guo Z,Li S,Liu Z,Chen P
Tue Dec 21 00:00:00 EST 2021
Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Oncology reports
Murphy A,Roy N,Sun H,Jin C,Costa M
Thu Apr 01 00:00:00 EDT 2021
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Cellular and molecular life sciences : CMLS
Zhang B,Chen Y,Shi X,Zhou M,Bao L,Hatanpaa KJ,Patel T,DeBerardinis RJ,Wang Y,Luo W
Fri Jan 01 00:00:00 EST 2021
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Theranostics
Chen X,Wang C,Sun N,Pan S,Li R,Li X,Zhao J,Tong H,Tang Y,Han J,Qiao J,Qiu H,Wang H,Yang J,Ikezoe T
Mon Aug 16 00:00:00 EDT 2021
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Cell research
Peng F,Xu J,Cui B,Liang Q,Zeng S,He B,Zou H,Li M,Zhao H,Meng Y,Chen J,Liu B,Lv S,Chu P,An F,Wang Z,Huang J,Zhan Y,Liao Y,Lu J,Xu L,Zhang J,Sun Z,Li Z,Wang F,Lam EW,Liu Q
Mon Mar 01 00:00:00 EST 2021
Cinnabar protects serum-nutrient starvation induced apoptosis by improving intracellular oxidative stress and inhibiting the expression of CHOP and PERK.
Biochemistry and biophysics reports
Ma HH,Ding YN,Wang A,Li X,Wang Y,Shi FG,Lu YF
Wed Sep 01 00:00:00 EDT 2021
A novel peptide promotes human trophoblast proliferation and migration through PI3K/Akt/mTOR signaling pathway.
Annals of translational medicine
Ling L,Yuan X,Liu X,Pei W,Li R
Tue Jun 01 00:00:00 EDT 2021
Quadruple-editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS-mutated colorectal cancer cells.
Cancer science
Wang Z,Kang B,Gao Q,Huang L,Di J,Fan Y,Yu J,Jiang B,Gao F,Wang D,Sun H,Gu Y,Li J,Su X
Wed Sep 01 00:00:00 EDT 2021
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Huang L,Zhang H,Zhao D,Hu H,Lu Z
Fri Oct 01 00:00:00 EDT 2021
CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages.
Biochemical and biophysical research communications
Wen S,Arakawa H,Tamai I
Fri Dec 03 00:00:00 EST 2021
Adipose expression of CREB3L3 modulates body weight during obesity.
Scientific reports
McCann MA,Li Y,Muñoz M,Gil V,Qiang G,Cordoba-Chacon J,Blüher M,Duncan S,Liew CW
Wed Sep 29 00:00:00 EDT 2021
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Nature communications
Barroso-Gomila O,Trulsson F,Muratore V,Canosa I,Merino-Cacho L,Cortazar AR,Pérez C,Azkargorta M,Iloro I,Carracedo A,Aransay AM,Elortza F,Mayor U,Vertegaal ACO,Barrio R,Sutherland JD
Thu Nov 18 00:00:00 EST 2021
Effects of transforming growth factor-β1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level.
Biochemical and biophysical research communications
Zhang Y,Zhang H,Yuan G,Yang G
Fri Mar 19 00:00:00 EDT 2021
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Frontiers in cell and developmental biology
Xie C,Zhu J,Yang X,Huang C,Zhou L,Meng Z,Li X,Zhong C
Tue Mar 23 00:00:00 EDT 2021
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis.
JCI insight
Beppu LY,Mooli RGR,Qu X,Marrero GJ,Finley CA,Fooks AN,Mullen ZP,Frias AB,Sipula I,Xie B,Helfrich KE,Watkins SC,Poholek AC,Ramakrishnan SK,Jurczak MJ,D'Cruz LM
Mon Feb 08 00:00:00 EST 2021
Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation.
Evidence-based complementary and alternative medicine : eCAM
Zhu JP,Wu HY,Zi Y,Xia XB,Xie MZ,Yuan ZY
Sat Sep 04 00:00:00 EDT 2021
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
European journal of pharmacology
Lv Y,Ma P,Wang J,Xu Q,Fan J,Yan L,Ma P,Zhou R
Fri Nov 05 00:00:00 EDT 2021
miR-182-5p and miR-96-5p Target PIAS1 and Mediate the Negative Feedback Regulatory Loop between PIAS1 and STAT3 in Endometrial Cancer.
DNA and cell biology
Xiao Y,Huang W,Huang H,Wang L,Wang M,Zhang T,Fang X,Xia X
Thu Apr 01 00:00:00 EDT 2021
Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling.
Frontiers in endocrinology
Cao T,Chen Q,Zhang B,Wu X,Zeng C,Zhang S,Cai H
Mon Feb 14 00:00:00 EST 2022
Exosomal MIF Derived From Nasopharyngeal Carcinoma Promotes Metastasis by Repressing Ferroptosis of Macrophages.
Frontiers in cell and developmental biology
Chen W,Zuo F,Zhang K,Xia T,Lei W,Zhang Z,Bao L,You Y
Wed Jan 19 00:00:00 EST 2022
Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics.
Pharmacological research
Zhuang S,Xia S,Huang P,Wu J,Qu J,Chen R,Sun N,Li D,Wu H,Zhang M,Zhang J,Yuan X,Wang X
Sun Aug 01 00:00:00 EDT 2021
Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway.
Frontiers in medicine
Fang S,Zhang P,Chen X,Liu F,Wang F
Tue Jan 04 00:00:00 EST 2022
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
PeerJ
Lei X,Chen G,Li J,Wen W,Gong J,Fu J
Wed Apr 27 00:00:00 EDT 2022
Perampanel Stimulates Mitochondrial Biogenesis in Neuronal Cells through Activation of the SIRT1/PGC-1α Signaling Pathway.
ACS chemical neuroscience
Jiang Y,Li D,Du Z,Li J,Lu R,Zhou Q,Wang Q,Zhu H
Wed Jan 20 00:00:00 EST 2021
Isorhamnetin Promotes Estrogen Biosynthesis and Proliferation in Porcine Granulosa Cells via the PI3K/Akt Signaling Pathway.
Journal of agricultural and food chemistry
Li X,Chen H,Zhang Z,Xu D,Duan J,Li X,Yang L,Hua R,Cheng J,Li Q
Wed Jun 16 00:00:00 EDT 2021
Extract of Cynomorium songaricum ameliorates mitochondrial ultrastructure impairments and dysfunction in two different in vitro models of Alzheimer's disease.
BMC complementary medicine and therapies
Cheng D,Su L,Wang X,Li X,Li L,Hu M,Lu Y
Mon Aug 09 00:00:00 EDT 2021
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Frontiers in pharmacology
Xu ZQ,Zhang JJ,Kong N,Zhang GY,Ke P,Han T,Su DF,Liu C
Tue May 18 00:00:00 EDT 2021
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Kong L,Dong R,Huang K,Wang X,Wang D,Yue N,Wang C,Sun P,Gu J,Luo H,Liu K,Wu J,Sun H,Meng Q
Wed Sep 01 00:00:00 EDT 2021
Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.
Chinese herbal medicines
Li X,Jiang XW,Chu HX,Zhao QC,Ding HW,Cai CH
Fri Jan 01 00:00:00 EST 2021
Targeting chromosome trisomy for chromosome editing.
Scientific reports
Abe T,Suzuki Y,Ikeya T,Hirota K
Fri Sep 10 00:00:00 EDT 2021
Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF.
PLoS pathogens
Rastogi S,Ellinwood S,Augenstreich J,Mayer-Barber KD,Briken V
Thu Jul 01 00:00:00 EDT 2021
Deficiency of Sirtuin 1 Impedes Endometrial Decidualization in Recurrent Implantation Failure Patients.
Frontiers in cell and developmental biology
Li J,Qi J,Yao G,Zhu Q,Li X,Xu R,Zhu Z,Zhao H,Wang Y,Ding Y,Sun Y
Tue Feb 16 00:00:00 EST 2021
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
Signal transduction and targeted therapy
Kang JW,Zhan Z,Ji G,Sang Y,Zhou D,Li Y,Feng H,Cheng T
Wed Mar 31 00:00:00 EDT 2021
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Frontiers in pharmacology
Zou M,Chen Y,Zheng Z,Sheng S,Jia Y,Wang X,Ren S,Yang Y,Li X,Dong W,Guan M,Zhang Q,Xue Y
Fri Jan 07 00:00:00 EST 2022
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Journal of applied toxicology : JAT
Dai W,He QZ,Zhu BQ,Zeng HC
Mon Nov 01 00:00:00 EDT 2021
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Journal of cellular physiology
Cheng X,He D,Liao C,Lin S,Tang L,Wang YL,Hu J,Li W,Liu Z,Wu Y,Liao Y
Sat May 01 00:00:00 EDT 2021
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Archives of pharmacal research
Zheng X,Liu H,Ma M,Ji J,Zhu F,Sun L
Thu Apr 01 00:00:00 EDT 2021
Perinatal low-dose bisphenol AF exposure impairs synaptic plasticity and cognitive function of adult offspring in a sex-dependent manner.
The Science of the total environment
Zhang C,Wu XC,Li S,Dou LJ,Zhou L,Wang FH,Ma K,Huang D,Pan Y,Gu JJ,Cao JY,Wang H,Hao JH
Mon Sep 20 00:00:00 EDT 2021
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
Cell death & disease
Wang H,Wei W,Zhang ZY,Liu Y,Shi B,Zhong W,Zhang HS,Fang X,Sun CL,Wang JB,Liu LX
Fri Dec 17 00:00:00 EST 2021
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Journal of molecular histology
Guo Z,Yu B,Li X,Yang X,Wang C,Fan L
Sun Aug 01 00:00:00 EDT 2021
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Cell reports
Ulferts R,Marcassa E,Timimi L,Lee LC,Daley A,Montaner B,Turner SD,Florey O,Baillie JK,Beale R
Tue Oct 26 00:00:00 EDT 2021
PKC-β/Alox5 axis activation promotes Bcr-Abl-independent TKI-resistance in chronic myeloid leukemia.
Journal of cellular physiology
Ma D,Liu P,Wang P,Zhou Z,Fang Q,Wang J
Wed Sep 01 00:00:00 EDT 2021
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
Scientific reports
Hirata Y,Takahashi M,Yamada Y,Matsui R,Inoue A,Ashida R,Noguchi T,Matsuzawa A
Fri May 14 00:00:00 EDT 2021
The Anti-Colon Cancer Effects of Essential Oil of Curcuma phaeocaulis Through Tumour Vessel Normalisation.
Frontiers in oncology
Feng Y,Deng L,Guo H,Zhao Y,Peng F,Wang G,Yu C
Thu Apr 28 00:00:00 EDT 2022
Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.
Cellular & molecular immunology
Tartey S,Gurung P,Karki R,Burton A,Hertzog P,Kanneganti TD
Thu Jul 01 00:00:00 EDT 2021
Total Flavonoids of Engelhardia roxburghiana Wall. Leaves Alleviated Foam Cells Formation through AKT/mTOR-Mediated Autophagy in the Progression of Atherosclerosis.
Chemistry & biodiversity
Wei J,Huang L,Li D,He J,Li Y,He F,Fang W,Wei G
Wed Sep 01 00:00:00 EDT 2021
Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway.
FEBS open bio
Wei N,Lu T,Yang L,Dong Y,Liu X
Sun Aug 01 00:00:00 EDT 2021
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Reproductive biology and endocrinology : RB&E
Tang X,Li Q,Li L,Jiang J
Tue Mar 09 00:00:00 EST 2021
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain.
Science advances
Choi EB,Vodnala M,Zerbato M,Wang J,Ho JJ,Inouye C,Ding L,Fong YW
Fri Oct 29 00:00:00 EDT 2021
5-HT7 Receptor Is Involved in Electroacupuncture Inhibition of Chronic Pain in the Spinal Cord.
Frontiers in neuroscience
Yuan XC,Yan XJ,Tian LX,Guo YX,Zhao YL,Baba SS,Wang YY,Liang LL,Jia H,Xu LP,Li L,Lin H,Huo FQ
Tue Oct 05 00:00:00 EDT 2021
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Neurological research
Deng L,Guo Y,Liu J,Chen S,Wang X,Zhao H,Zuo T,Hu Q,Dong Z
Wed Sep 01 00:00:00 EDT 2021
Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.
Canadian journal of physiology and pharmacology
Wang G,Chen S,Shao Z,Li Y,Wang W,Mao L,Li J,Mei X
Sun Aug 01 00:00:00 EDT 2021
Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK).
Journal of endocrinological investigation
Sun WX,Lou K,Chen LJ,Liu SD,Pang SG
Sun Aug 01 00:00:00 EDT 2021
Chitosan Protects Immunosuppressed Mice Against Cryptosporidium parvum Infection Through TLR4/STAT1 Signaling Pathways and Gut Microbiota Modulation.
Frontiers in immunology
Rahman SU,Gong H,Mi R,Huang Y,Han X,Chen Z
Thu Feb 24 00:00:00 EST 2022
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
Frontiers in oncology
Xu TT,Zeng XW,Wang XH,Yang LX,Luo G,Yu T
Sat Sep 11 00:00:00 EDT 2021
Ketamine enhances novel object recognition memory reconsolidation via the BDNF/TrkB pathway in mice.
Physiology & behavior
Fan JF,Tang ZH,Wang SY,Lei S,Zhang B,Tian SW
Wed Dec 01 00:00:00 EST 2021
Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer.
Cancers
Bosch-Barrera J,Verdura S,Ruffinelli JC,Carcereny E,Sais E,Cuyàs E,Palmero R,Lopez-Bonet E,Hernández-Martínez A,Oliveras G,Buxó M,Izquierdo A,Morán T,Nadal E,Menendez JA
Thu Aug 19 00:00:00 EDT 2021
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Frontiers in pharmacology
Yong C,Zhang Z,Huang G,Yang Y,Zhu Y,Qian L,Tian F,Liu L,Wu Q,Xu Z,Chen C,Zhao J,Gao K,Zhou E
Wed Dec 15 00:00:00 EST 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
Piezo2 channel in nodose ganglia neurons is essential in controlling hypertension in a pathway regulated directly by Nedd4-2.
Pharmacological research
Huo L,Gao Y,Zhang D,Wang S,Han Y,Men H,Yang Z,Qin X,Wang R,Kong D,Bai H,Zhang H,Zhang W,Jia Z
Mon Feb 01 00:00:00 EST 2021
C1orf61 promotes hepatocellular carcinoma metastasis and increases the therapeutic response to sorafenib.
Biochimica et biophysica acta. Molecular cell research
Yu Y,Wang Z,Huang Z,Tang X,Huang X,Li W
Thu Jul 01 00:00:00 EDT 2021
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial-Mesenchymal Transition.
OncoTargets and therapy
Gong L,Cai L,Li G,Cai J,Yi X
Wed Apr 20 00:00:00 EDT 2022
Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer.
Scientific reports
Oba T,Sato N,Adachi Y,Amaike T,Kudo Y,Koga A,Kohi S,Hirata K
Tue Sep 14 00:00:00 EDT 2021
Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis.
Cancer management and research
Zhong H,Zeng G,He L
Tue Apr 26 00:00:00 EDT 2022
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin.
Cell death & disease
Xu Z,Zheng J,Chen Z,Guo J,Li X,Wang X,Qu C,Yuan L,Cheng C,Sun X,Yu J
Mon Jun 07 00:00:00 EDT 2021
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Medical oncology (Northwood, London, England)
Yan S,Yuan D,Li Q,Li S,Zhang F
Wed Nov 10 00:00:00 EST 2021
ERα promotes transcription of tumor suppressor gene ApoA-I by establishing H3K27ac-enriched chromatin microenvironment in breast cancer cells.
Journal of Zhejiang University. Science. B
Wang B,Shen Y,Liu T,Tan L
Wed Dec 15 00:00:00 EST 2021
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Molecular medicine (Cambridge, Mass.)
Lu L,Zhong Z,Gu J,Nan K,Zhu M,Miao C
Thu Jul 08 00:00:00 EDT 2021
RNA N6 -methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector.
Molecular plant pathology
Tian S,Wu N,Zhang L,Wang X
Wed Sep 01 00:00:00 EDT 2021
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jia X,Zhu H,Li G,Lan M,Li X,Huang M,Xu W,Wu S
Sat May 01 00:00:00 EDT 2021
PAX5-activated lncRNA ARRDC1-AS1 accelerates the autophagy and progression of DLBCL through sponging miR-2355-5p to regulate ATG5.
Life sciences
Xu H,Yu X,Yang Z,Song Q,Cheng S,He Z,Dai L
Wed Dec 01 00:00:00 EST 2021
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nature metabolism
Zhang X,Li N,Zhang J,Zhang Y,Yang X,Luo Y,Zhang B,Xu Z,Zhu Z,Yang X,Yan Y,Lin B,Wang S,Chen D,Ye C,Ding Y,Lou M,Wu Q,Hou Z,Zhang K,Liang Z,Wei A,Wang B,Wang C,Jiang N,Zhang W,Xiao G,Ma C,Ren Y,Qi X,Han W,Wang C,Rao F
Fri Oct 01 00:00:00 EDT 2021
Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling.
Journal of inflammation research
Yao Y,Li C,Qian F,Zhao Y,Shi X,Hong D,Ai Q,Zhong L
Fri Jun 16 00:00:00 EDT 2023
Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma.
Frontiers in pharmacology
Guo SS,Liang YJ,Liu LT,Chen QY,Wen YF,Liu SL,Sun XS,Tang QN,Li XY,Mai HQ,Tang LQ
Tue Sep 14 00:00:00 EDT 2021
Targeted radioimmunotherapy with the iodine-131-labeled caerin 1.1 peptide for human anaplastic thyroid cancer in nude mice.
Annals of nuclear medicine
Lin R,Ma B,Liu N,Zhang L,He T,Liu X,Chen T,Liu W,Liang Y,Wang T,Ni G,Liu X,Yang N,Zhang J,Yuan J
Thu Jul 01 00:00:00 EDT 2021
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology.
Frontiers in pharmacology
Yi N,Mi Y,Xu X,Li N,Zeng F,Yan K,Tan K,Kuang G,Lu M
Fri Jan 28 00:00:00 EST 2022
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Nature
Lee S,Karki R,Wang Y,Nguyen LN,Kalathur RC,Kanneganti TD
Wed Sep 01 00:00:00 EDT 2021
HOXA5 Is Recognized as a Prognostic-Related Biomarker and Promotes Glioma Progression Through Affecting Cell Cycle.
Frontiers in oncology
Ding F,Chen P,Bie P,Piao W,Cheng Q
Tue Sep 07 00:00:00 EDT 2021
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
Translational pediatrics
Yin Y,Qu L,Zhu D,Wu Y,Zhou X
Tue Jun 01 00:00:00 EDT 2021
Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization.
American journal of translational research
Wang Y,Cui J,Liu M,Shao Y,Dong X
Wed Feb 03 00:00:00 EST 2021
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Journal of receptor and signal transduction research
Ma X,Zhang J,Wu Z,Wang X
Sun Aug 01 00:00:00 EDT 2021
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Nature communications
Shi W,Zhang G,Ma Z,Li L,Liu M,Qin L,Yu Z,Zhao L,Liu Y,Zhang X,Qin J,Ye H,Jiang X,Zhou H,Sun H,Jiao Z
Fri May 14 00:00:00 EDT 2021
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Ecotoxicology and environmental safety
Liu C,Qu J,Wu M,Huang X,Li L
Wed Dec 01 00:00:00 EST 2021
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
Life sciences
He J,Huang Y,Liu J,Ge L,Tang X,Lu M,Hu Z
Fri Jan 15 00:00:00 EST 2021
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
Bioengineered
Zhou J,Wu H,Guo C,Li B,Zhou LL,Liang AB,Fu JF
Wed Dec 01 00:00:00 EST 2021
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Food science & nutrition
Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F
Thu Jul 01 00:00:00 EDT 2021
Redd1 knockdown prevents doxorubicin-induced cardiac senescence.
Aging
Huang P,Bai L,Liu L,Fu J,Wu K,Liu H,Liu Y,Qi B,Qi B
Thu May 06 00:00:00 EDT 2021
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Cell proliferation
Wang Z,Su G,Dai Z,Meng M,Zhang H,Fan F,Liu Z,Zhang L,Weygant N,He F,Fang N,Zhang L,Cheng Q
Mon Mar 01 00:00:00 EST 2021
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Frontiers in genetics
Qiao Y,Chen Y,Tan C,Sun X,Chen X,Chen J
Tue Dec 28 00:00:00 EST 2021
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Oncology letters
Yang F,Yuan WQ,Li J,Luo YQ
Wed Dec 01 00:00:00 EST 2021
A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells.
Scientific reports
Ho KT,Homma K,Takanari J,Bai H,Kawahara M,Nguyen KTK,Takahashi M
Mon Sep 13 00:00:00 EDT 2021
Electroacupuncture Ameliorates Depression-Like Behaviour in Rats by Enhancing Synaptic Plasticity via the GluN2B/CaMKII/CREB Signalling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Zhang K,Liu R,Zhang J,Wei X,Gao Y,Ma W,Li Y,Cai W,Shen W
Thu Apr 28 00:00:00 EDT 2022
Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells.
Antioxidants (Basel, Switzerland)
Zhang YL,Chen GL,Liu Y,Zhuang XC,Guo MQ
Thu Sep 30 00:00:00 EDT 2021
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis.
Human cell
He Y,Ji D,Lu W,Li F,Huang X,Huang R,Chen G
Wed Sep 01 00:00:00 EDT 2021
Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Biochemical and biophysical research communications
Li Y,Zhao J,Wu Y,Xia L
Fri Apr 16 00:00:00 EDT 2021
Ze-Qi-Tang Formula Induces Granulocytic Myeloid-Derived Suppressor Cell Apoptosis via STAT3/S100A9/Bcl-2/Caspase-3 Signaling to Prolong the Survival of Mice with Orthotopic Lung Cancer.
Mediators of inflammation
Xu ZH,Zhu YZ,Su L,Tang XY,Yao C,Jiao XN,Hou YF,Chen X,Wei LY,Wang WT,Wang J,Gong CY,Zhu XD,Zhang F,Zhu SG,Zou CP
Mon Dec 06 00:00:00 EST 2021
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
Biochemical and biophysical research communications
Liu W,Liu J,Xing S,Pan X,Wei S,Zhou M,Li Z,Wang L,Bielicki JK
Fri Jun 04 00:00:00 EDT 2021
LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinoma.
Life sciences
Chen MH,Fu LS,Zhang F,Yang Y,Wu XZ
Wed Sep 01 00:00:00 EDT 2021
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Cell death and differentiation
Bao WD,Pang P,Zhou XT,Hu F,Xiong W,Chen K,Wang J,Wang F,Xie D,Hu YZ,Han ZT,Zhang HH,Wang WX,Nelson PT,Chen JG,Lu Y,Man HY,Liu D,Zhu LQ
Sat May 01 00:00:00 EDT 2021
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway.
Oxidative medicine and cellular longevity
Hu H,Xia N,Lin J,Li D,Zhang C,Ge M,Tian H,Mei X
Thu Jan 06 00:00:00 EST 2022
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Ecotoxicology and environmental safety
Li S,Wang X,Xiao Y,Wang Y,Wan Y,Li X,Li Q,Tang X,Cai D,Ran B,Wu C
Fri Jan 15 00:00:00 EST 2021
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Cell cycle (Georgetown, Tex.)
Wu T,Wang G,Zeng X,Sun Z,Li S,Wang W,Yu B
Wed Sep 01 00:00:00 EDT 2021
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Biochimica et biophysica acta. Molecular cell research
Yang C,Xu X,Dong X,Yang B,Dong W,Luo Y,Liu X,Wu Y,Wang J
Sun Aug 01 00:00:00 EDT 2021
Polysaccharides Extracted From Panax Ginseng C.A. Mey Enhance Complement Component 4 Biosynthesis in Human Hepatocytes.
Frontiers in pharmacology
Liu S,Liu F,Wang T,Liu J,Hu C,Sun L,Wang G
Wed Sep 29 00:00:00 EDT 2021
Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α.
Frontiers in cell and developmental biology
Wang M,Liu H,Zhang X,Zhao W,Lin X,Zhang F,Li D,Xu C,Xie F,Wu Z,Yang Q,Li X
Tue Sep 21 00:00:00 EDT 2021
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Oxidative medicine and cellular longevity
Wu D,Liu Z,Wang Y,Zhang Q,Li J,Zhong P,Xie Z,Ji A,Li Y
Fri May 28 00:00:00 EDT 2021
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice.
Clinical science (London, England : 1979)
Qian LL,Ji JJ,Guo JQ,Wu YP,Ma GS,Yao YY
Fri Feb 12 00:00:00 EST 2021
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Journal of inflammation research
Lin X,Zhan J,Jiang J,Ren Y
Sat Apr 23 00:00:00 EDT 2022
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model.
American journal of physiology. Lung cellular and molecular physiology
Wang T,Du X,Wang Z,Gu Y,Huang Q,Wu J,Zhan Y,Chen J,Xiao C,Xie J
Thu Jul 01 00:00:00 EDT 2021
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion.
Journal of experimental & clinical cancer research : CR
Fang W,Zhou T,Shi H,Yao M,Zhang D,Qian H,Zeng Q,Wang Y,Jin F,Chai C,Chen T
Mon Jan 04 00:00:00 EST 2021
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects.
Cell death & disease
Huang W,Huang T,Liu Y,Fu J,Wei X,Liu D,Ma W,Gu H,Yuan Z
Mon Dec 20 00:00:00 EST 2021
Integrated Analysis of Ferroptosis-Related Biomarker Signatures to Improve the Diagnosis and Prognosis Prediction of Ovarian Cancer.
Frontiers in cell and developmental biology
Wang H,Cheng Q,Chang K,Bao L,Yi X
Tue Jan 25 00:00:00 EST 2022
mTORC1-mediated amino acid signaling is critical for cell fate determination under transplant-induced stress.
FEBS letters
Cheng X,Ge M,Zhu S,Li D,Wang R,Xu Q,Chen Z,Xie S,Liu H
Mon Feb 01 00:00:00 EST 2021
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Biochemical pharmacology
Tan X,Guo W,Peng Z,Gu C,Xiang P,Tu Y,Fei H,Liu X,Lu Y,Li M,Wang H,Luo Y,Yang J
Fri Oct 01 00:00:00 EDT 2021
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Frontiers in neuroscience
Chang Y,Yao Y,Ma R,Wang Z,Hu J,Wu Y,Jiang X,Li L,Li G
Mon Jul 12 00:00:00 EDT 2021
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Scientific reports
Ouyang X,Wang Z,Luo M,Wang M,Liu X,Chen J,Feng J,Jia J,Wang X
Mon Sep 13 00:00:00 EDT 2021
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Free radical biology & medicine
Zeng L,Zhou J,Wang X,Zhang Y,Wang M,Su P
Sat Nov 20 00:00:00 EST 2021
WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells.
Nature communications
Wang L,Liu H,Zhang X,Song E,Wang Y,Xu T,Li Z
Tue Nov 30 00:00:00 EST 2021
Danshensu derivative ADTM ameliorates CCl4‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Pathology, research and practice
Jia S,Chen Q,Wu J,Yao X,Shao J,Cheng X,Zhang C,Cen D,Wang Y,Shen Z,Shan L,Yao X
Wed Dec 01 00:00:00 EST 2021
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Experimental cell research
Zhang F,Zhou X,Zou H,Liu L,Li X,Ruan Y,Xie Y,Shi M,Xiao Y,Wang Y,Zhou Y,Wu Y,Guo B
Mon Nov 01 00:00:00 EDT 2021
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro.
Journal of applied toxicology : JAT
Jiao L,Li S,Zhai J,Wang D,Li H,Chu W,Geng X,Du Y
Mon Nov 01 00:00:00 EDT 2021
Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
Cellular signalling
Zhang N,Wang G,Sun G
Wed Sep 01 00:00:00 EDT 2021
Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Science advances
Tong J,Wang X,Liu Y,Ren X,Wang A,Chen Z,Yao J,Mao K,Liu T,Meng FL,Pan W,Zou Q,Liu J,Zhou Y,Xia Q,Flavell RA,Zhu S,Li HB
Thu Apr 01 00:00:00 EDT 2021
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Cartilage
Shen PC,Chou SH,Lu CC,Huang HT,Chien SH,Huang PJ,Liu ZM,Shih CL,Su SJ,Chen LM,Tien YC
Wed Dec 01 00:00:00 EST 2021
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Ecotoxicology and environmental safety
Zhang Y,Guo S,Wang S,Li X,Hou D,Li H,Wang L,Xu Y,Ma B,Wang H,Jiang X
Wed Sep 01 00:00:00 EDT 2021
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Cellular signalling
Pan D,Yang W,Zeng Y,Li W,Wang K,Zhao L,Li J,Ye Y,Guo Q
Sun Aug 01 00:00:00 EDT 2021
Downregulation of SUN2 promotes metastasis of colon cancer by activating BDNF/TrkB signalling by interacting with SIRT1.
The Journal of pathology
Liu L,Li SW,Yuan W,Tang J,Sang Y
Sun Aug 01 00:00:00 EDT 2021
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zeng J,Tao J,Xia L,Zeng Z,Chen J,Wang Z,Meng J,Liu L
Tue Jun 01 00:00:00 EDT 2021
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Frontiers in oncology
Chen C,Zheng Q,Pan S,Chen W,Huang J,Cao Y,Tu Y,Li Z,Yu C,Jie Z
Sat Jul 24 00:00:00 EDT 2021
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
The Science of the total environment
Yang M,Wang D,Gan S,Wang B,Yu L,Xie Y,Fan L,Ma J,Chen W
Sun Oct 10 00:00:00 EDT 2021
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
International journal of molecular sciences
Khodayari N,Wang RL,Oshins R,Lu Y,Millett M,Aranyos AM,Mostofizadeh S,Scindia Y,Flagg TO,Brantly M
Thu Dec 09 00:00:00 EST 2021
Trophoblast-derived interleukin 9 mediates immune cell conversion and contributes to maternal-fetal tolerance.
Journal of reproductive immunology
Sun Y,Wu S,Zhou Q,Li X
Mon Nov 01 00:00:00 EDT 2021
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
Journal of ethnopharmacology
Tang L,Wang F,Xiao L,Shen M,Xia S,Zhang Z,Zhang F,Zheng S,Tan S
Mon Nov 15 00:00:00 EST 2021
A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Widyaningrum R,Burnouf T,Nebie O,Delila L,Wang TJ
Fri Oct 01 00:00:00 EDT 2021
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
BMC medicine
Xie X,Lv H,Liu C,Su X,Yu Z,Song S,Bian H,Tian M,Qin C,Qi J,Zhu Q
Fri Oct 15 00:00:00 EDT 2021
Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-κB and p38/MAPK signaling pathways in vitro.
International immunopharmacology
Duan C,Ge X,Wang J,Wei Z,Feng WH,Wang J
Thu Apr 01 00:00:00 EDT 2021
LncRNA MAYA promotes iron overload and hepatocyte senescence through inhibition of YAP in non-alcoholic fatty liver disease.
Journal of cellular and molecular medicine
Yuan P,Qi X,Song A,Ma M,Zhang X,Lu C,Bian M,Lian N,He J,Zheng S,Jin H
Sun Aug 01 00:00:00 EDT 2021
CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Journal of cellular and molecular medicine
Chen Z,Chen H,Yang L,Li X,Wang Z
Sun Aug 01 00:00:00 EDT 2021
Injection of Anti-proBDNF Attenuates Hippocampal-Dependent Learning and Memory Dysfunction in Mice With Sepsis-Associated Encephalopathy.
Frontiers in neuroscience
Cui YH,Zhou SF,Liu Y,Wang S,Li F,Dai RP,Hu ZL,Li CQ
Sat Aug 07 00:00:00 EDT 2021
Changes of lipid profiles in human umbilical vein endothelial cells exposed to zirconia nanoparticles with or without the presence of free fatty acids.
Journal of applied toxicology : JAT
Cheng X,Guo H,Xian Y,Xie X
Sat May 01 00:00:00 EDT 2021
A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.
Drug delivery
Liao L,Cen B,Li G,Wei Y,Wang Z,Huang W,He S,Yuan Y,Ji A
Wed Dec 01 00:00:00 EST 2021
Rutaecarpine alleviates acute pancreatitis in mice and AR42J cells by suppressing the MAPK and NF-κB signaling pathways via calcitonin gene-related peptide.
Phytotherapy research : PTR
Huang H,Wang M,Guo Z,Wu D,Wang H,Jia Y,Liu H,Ding J,Peng J
Mon Nov 01 00:00:00 EDT 2021
Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.
Cell death discovery
Liu W,Wang Y,Xie Y,Dai T,Fan M,Li C,Zou Y
Sat Jun 05 00:00:00 EDT 2021
Upregulation of silent information regulator 1 alleviates mitochondrial dysfunction in the trigeminal nucleus caudalis in a rat model of chronic migraine.
Neuroreport
Liang J,Zhou X,Wang J,Fei ZY,Qin GC,Zhang DK,Zhou JY,Chen LX
Wed Jan 13 00:00:00 EST 2021
Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells.
Frontiers in pharmacology
Yang Q,Li Y,Sun R,Li J
Tue May 18 00:00:00 EDT 2021
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Cell calcium
Chen Y,Hu M,Deng F,Wang P,Lin J,Zheng Z,Liu Y,Dong L,Lu X,Chen Z,Zhou J,Zuo D
Wed Dec 01 00:00:00 EST 2021
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
Oxidative medicine and cellular longevity
He J,Liu J,Huang Y,Tang X,Xiao H,Liu Z,Jiang Z,Zeng L,Hu Z,Lu M
Mon Feb 07 00:00:00 EST 2022
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter.
Oncogene
Wu S,Liu B,Zhang Y,Hong R,Liu S,Xiang T,Tao T,Cai J,Wu J,Li M,Guan H
Sat May 01 00:00:00 EDT 2021
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Frontiers in pharmacology
Gao M,Yang J,Gong H,Lin Y,Liu J
Wed Nov 10 00:00:00 EST 2021
Tanshinone I Mitigates Steroid-Induced Osteonecrosis of the Femoral Head and Activates the Nrf2 Signaling Pathway in Rats.
Evidence-based complementary and alternative medicine : eCAM
Xu X,Shen Y,Lv H,Zhao J,Li X,Gao L,Ren S,Zhang X
Fri Feb 04 00:00:00 EST 2022
Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy.
Oxidative medicine and cellular longevity
Wang Y,Hu Y,Wang H,Liu N,Luo L,Zhao C,Zhou D,Tong H,Li P,Zhou Q
Thu Dec 30 00:00:00 EST 2021
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Frontiers in cell and developmental biology
Lin Z,Ni L,Teng C,Zhang Z,Wu L,Jin Y,Lu X,Lin Z
Tue Nov 23 00:00:00 EST 2021
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Journal of agricultural and food chemistry
Liu H,Liang J,Zhong Y,Xiao G,Efferth T,Georgiev MI,Vargas-De-La-Cruz C,Bajpai VK,Caprioli G,Liu J,Lin J,Wu H,Peng L,Li Y,Ma L,Xiao J,Wang Q
Wed Nov 17 00:00:00 EST 2021
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Frontiers in microbiology
Xu Y,Xie L,Tang J,He X,Zhang Z,Chen Y,Zhou J,Gan B,Peng W
Sat Sep 25 00:00:00 EDT 2021
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Nutrients
Lin L,Zeng L,Liu A,Yuan D,Peng Y,Zhang S,Li Y,Chen J,Xiao W,Gong Z
Wed Nov 17 00:00:00 EST 2021
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Frontiers in cardiovascular medicine
Li Q,Xu M,Li Z,Li T,Wang Y,Chen Q,Wang Y,Feng J,Yin X,Lu C
Sat Dec 04 00:00:00 EST 2021
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure.
Toxicology research
Liu Y,Wen C,Zhang Y,Liu Z,He Q,Cui M,Peng H,Wang Y,Zhang X,Li X,Wang Q
Fri Oct 01 00:00:00 EDT 2021
Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.
The European journal of neuroscience
Wu J,Fan Z,Zhao Y,Chen Q,Xiao Q
Thu Apr 01 00:00:00 EDT 2021
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway.
BMC cancer
Wang H,Fu Y
Fri Jul 30 00:00:00 EDT 2021
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis.
Molecular cancer
Rong Z,Shi S,Tan Z,Xu J,Meng Q,Hua J,Liu J,Zhang B,Wang W,Yu X,Liang C
Sat Aug 21 00:00:00 EDT 2021
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Aging cell
Dang R,Yang M,Cui C,Wang C,Zhang W,Geng C,Han W,Jiang P
Fri Oct 01 00:00:00 EDT 2021
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Toxicology
Liu YN,Mu YD,Wang H,Zhang M,Shi YW,Mi G,Peng LX,Chen JH
Wed Dec 01 00:00:00 EST 2021
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Human & experimental toxicology
Liu X,Li M,Zhu J,Huang W,Song J
Thu Jul 01 00:00:00 EDT 2021
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Ecotoxicology and environmental safety
Chen Z,Liang Y,Lu Q,Nazar M,Mao Y,Aboragah A,Yang Z,Loor JJ
Fri Oct 01 00:00:00 EDT 2021
Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.
Frontiers in pharmacology
Wang R,Wang Z,Sun R,Fu R,Sun Y,Zhu M,Geng Y,Gao D,Tian X,Zhao Y,Yao J
Tue Dec 21 00:00:00 EST 2021
Baicalein Delays H2O2-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
ACS chemical neuroscience
Gao L,Zheng WG,Wu XK,Du GH,Qin XM
Wed Jul 07 00:00:00 EDT 2021
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
The Journal of clinical investigation
Singhal R,Mitta SR,Das NK,Kerk SA,Sajjakulnukit P,Solanki S,Andren A,Kumar R,Olive KP,Banerjee R,Lyssiotis CA,Shah YM
Tue Jun 15 00:00:00 EDT 2021
DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
Bone
Yang B,Sun H,Jia M,He Y,Luo Y,Wang T,Wu Y,Wang J
Wed Dec 01 00:00:00 EST 2021
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Neurochemical research
Deng L,Guo Y,Liu J,Wang X,Chen S,Wang Q,Rao J,Wang Y,Zuo T,Hu Q,Zhao X,Dong Z
Thu Jul 01 00:00:00 EDT 2021
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Cell death & disease
Wang Y,Yuan J,Yu X,Liu X,Tan C,Chen Y,Xu T
Tue Oct 12 00:00:00 EDT 2021
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Peng X,Hao M,Zhao Y,Cai Y,Chen X,Chen H,Zhang Y,Dong L,Liu X,Ding C,Liu W,Yang M,Luo Y
Wed Dec 01 00:00:00 EST 2021
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
PloS one
Qiao J,Peng Q,Qian F,You Q,Feng L,Hu S,Liu W,Huang L,Shu X,Sun B
Mon Jan 17 00:00:00 EST 2022
Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li Q,Zhang Y,Yang Y,Huang S,Zou X,Wei C,Liang T,Zhong X
Fri Oct 01 00:00:00 EDT 2021
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma.
Leukemia & lymphoma
Chen Q,Liu S,Zhang K,Yu B,Zhang W,Zhang H,Chen X
Mon Nov 01 00:00:00 EDT 2021
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
BMC cancer
Jiao X,Wang B,Feng C,Song S,Tian B,Zhou C,Gao X,Sun W,Liu P
Wed Jun 30 00:00:00 EDT 2021
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Nature communications
Zhang M,Wang J,Zhang K,Lu G,Liu Y,Ren K,Wang W,Xin D,Xu L,Mao H,Xing J,Gao X,Jin W,Berry K,Mikoshiba K,Wu S,Lu QR,Zhao X
Tue Aug 24 00:00:00 EDT 2021
The COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway.
Scientific reports
Li T,Ling Z,Xie K,Wang Y,Miao Z,Ji X,Li J,Hou W,Tang Q,Yuan X,Li N,Li C,Ding H
Tue Aug 03 00:00:00 EDT 2021
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
International journal of biological sciences
Bai M,Cui M,Li M,Yao X,Wu Y,Zheng L,Sun L,Song Q,Wang S,Liu L,Yu C,Huang Y
Tue Feb 22 00:00:00 EST 2022
An Antioxidant Sesquiterpene Inhibits Osteoclastogenesis Via Blocking IPMK/TRAF6 and Counteracts OVX-Induced Osteoporosis in Mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang S,Ma Q,Xie Z,Shen Y,Zheng B,Jiang C,Yuan P,An Q,Fan S,Jie Z
Wed Sep 01 00:00:00 EDT 2021
Neu1 deficiency induces abnormal emotional behavior in zebrafish.
Scientific reports
Ikeda A,Komamizu M,Hayashi A,Yamasaki C,Okada K,Kawabe M,Komatsu M,Shiozaki K
Tue Jun 29 00:00:00 EDT 2021
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Drug design, development and therapy
Ma L,Wu F,Shao Q,Chen G,Xu L,Lu F
Mon Jan 10 00:00:00 EST 2022
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Journal of experimental & clinical cancer research : CR
Liu S,Chen L,Chen H,Xu K,Peng X,Zhang M
Fri Feb 12 00:00:00 EST 2021
Subicular Caspase-1 Contributes to Pharmacoresistance in Temporal Lobe Epilepsy.
Annals of neurology
Xu C,Zhang S,Gong Y,Nao J,Shen Y,Tan B,Xu S,Cui S,Ruan Y,Wang S,Wang Y,Chen Z
Wed Sep 01 00:00:00 EDT 2021
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Frontiers in oncology
Zhao J,Jiang Y,Chen L,Ma Y,Zhang H,Zhou J,Li H,Jing Z
Fri Aug 20 00:00:00 EDT 2021
Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids.
Virologica Sinica
Chen X,Yang X,Lei C,Qin F,Sun X,Hu J
Fri Oct 01 00:00:00 EDT 2021
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
BMC cancer
Wang F,Wang L,Qu C,Chen L,Geng Y,Cheng C,Yu S,Wang D,Yang L,Meng Z,Chen Z
Mon Apr 12 00:00:00 EDT 2021
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Experimental and molecular pathology
Guo C,Zhou S,Yi W,Yang P,Li O,Liu J,Peng C
Tue Jun 01 00:00:00 EDT 2021
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
Theranostics
Wang Q,Liu J,Hu Y,Pan T,Xu Y,Yu J,Xiong W,Zhou Q,Wang Y
Thu Aug 05 00:00:00 EDT 2021
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
NanoImpact
Liu Y,Hu Q,Huang C,Cao Y
Thu Jul 01 00:00:00 EDT 2021
Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine.
Neuroscience letters
Niu Y,Zeng X,Qin G,Zhang D,Zhou J,Chen L
Tue Jan 19 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Frontiers in cell and developmental biology
Nie Q,Chen H,Zou M,Wang L,Hou M,Xiang JW,Luo Z,Gong XD,Fu JL,Wang Y,Zheng SY,Xiao Y,Gan YW,Gao Q,Bai YY,Wang JM,Zhang L,Tang XC,Hu X,Gong L,Liu Y,Li DW
Fri Jul 02 00:00:00 EDT 2021
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Biochemical and biophysical research communications
Meng Y,Yang L,Wei X,Luo H,Hu Y,Tao X,He J,Zheng X,Xu Q,Luo K,Yu G,Luo Q
Fri Aug 27 00:00:00 EDT 2021
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Biochimica et biophysica acta. Molecular cell research
Yao S,Jiang C,Zhang H,Gao X,Guo Y,Cao Z
Thu Jul 01 00:00:00 EDT 2021
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
International journal of biological sciences
Wang J,Liu R,Mo H,Xiao X,Xu Q,Zhao W
Tue Feb 22 00:00:00 EST 2022
Suppressing Alpha-Hemolysin as Potential Target to Screen of Flavonoids to Combat Bacterial Coinfection.
Molecules (Basel, Switzerland)
He S,Deng Q,Liang B,Yu F,Yu X,Guo D,Liu X,Dong H
Tue Dec 14 00:00:00 EST 2021
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation.
Veterinary research
Wang Q,Chang X,Liu M,Lu Q,Zhu M,Lin H,Fan H
Thu Oct 21 00:00:00 EDT 2021
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
Oxidative medicine and cellular longevity
Li Y,Yuan Y,Li Y,Han D,Liu T,Yang N,Mi X,Hong J,Liu K,Song Y,He J,Zhou Y,Han Y,Shi C,Yu S,Zou P,Guo X,Li Z
Tue Jan 04 00:00:00 EST 2022
Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway.
Molecular medicine reports
Li D,Wang L,Ou J,Wang C,Zhou J,Lu L,Wu Y,Gao J
Fri Oct 01 00:00:00 EDT 2021
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.
Free radical biology & medicine
Jia R,Yang F,Yan P,Ma L,Yang L,Li L
Tue Jun 01 00:00:00 EDT 2021
Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway.
Annals of translational medicine
Bai S,Chen W,Zheng M,Wang X,Peng W,Zhao Y,Wang Y,Xiong S,Cheng B
Wed Sep 01 00:00:00 EDT 2021
Competing endogenous RNA network associated with oxygen-induced retinopathy: Expression of the network and identification of the MALAT1/miR-124-3p/EGR1 regulatory axis.
Experimental cell research
Xia F,Xu Y,Zhang X,Lyu J,Zhao P
Mon Nov 01 00:00:00 EDT 2021
ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
International journal of clinical and experimental pathology
Gao L,Liu H,Xu R,Qiu J,Peng X,Yang Y,Zhang D,Qian J
Tue Aug 10 00:00:00 EDT 2021
Purification, characterization and anti-atherosclerotic effects of the polysaccharides from the fruiting body of Cordyceps militaris.
International journal of biological macromolecules
Yang X,Lin P,Wang J,Liu N,Yin F,Shen N,Guo S
Wed Jun 30 00:00:00 EDT 2021
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Ecotoxicology and environmental safety
Zhao G,Qi L,Wang Y,Li X,Li Q,Tang X,Wang X,Wu C
Fri Oct 01 00:00:00 EDT 2021
MicroRNA ssc-miR-124a exhibits antiviral activity against porcine reproductive and respiratory syndrome virus via suppression of host genes CD163.
Veterinary microbiology
Li N,Huang K,Chen Y,Huang Z,Zhang Y,Leng C,Liu Y,Shi J,Xiao S,Yao L
Fri Oct 01 00:00:00 EDT 2021
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Metabolic brain disease
Kambey PA,Chengcheng M,Xiaoxiao G,Abdulrahman AA,Kanwore K,Nadeem I,Jiao W,Gao D
Thu Apr 01 00:00:00 EDT 2021
Immunization with recombinant Erns-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Veterinary microbiology
Wang SH,Yang GH,Nie JW,Wang J,Wang YX,Du MZ,Guo L,Yang RJ,Zhu YH
Sun Aug 01 00:00:00 EDT 2021
TRIM29 Reverses Oxaliplatin Resistance of P53 Mutant Colon Cancer Cell.
Canadian journal of gastroenterology & hepatology
Lei G,Liu S,Yang X,He C
Wed Aug 18 00:00:00 EDT 2021
Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway.
American journal of translational research
Dong XH,Zhang MZ,Lai CZ,Li CC,Du L,Song GD,Zong XL,Jin XL
Thu Nov 18 00:00:00 EST 2021
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Scientific reports
Zhao Y,Liu X,Zheng Y,Liu W,Ding C
Mon Oct 18 00:00:00 EDT 2021
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
ACS nano
Jiang M,Li X,Zhang J,Lu Y,Shi Y,Zhu C,Liu Y,Qin B,Luo Z,Du Y,Luo L,Peng L,You J
Tue Sep 28 00:00:00 EDT 2021
Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways.
Evidence-based complementary and alternative medicine : eCAM
Liu L,Xu Z,Yu B,Tao L,Cao Y
Tue Jul 27 00:00:00 EDT 2021
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Ecotoxicology and environmental safety
Guo H,Yang Y,Qiao Y,He J,Yao W,Zheng W
Mon Dec 20 00:00:00 EST 2021
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Journal of medical virology
Han L,Zhuang MW,Deng J,Zheng Y,Zhang J,Nan ML,Zhang XJ,Gao C,Wang PH
Wed Sep 01 00:00:00 EDT 2021
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
Experimental cell research
Zhang J,Qiu Q,Wang H,Chen C,Luo D
Fri Oct 15 00:00:00 EDT 2021
Duck Hepatitis A Virus Type 1 Induces eIF2α Phosphorylation-Dependent Cellular Translation Shutoff via PERK/GCN2.
Frontiers in microbiology
Liu Y,Cheng A,Wang M,Mao S,Ou X,Yang Q,Wu Y,Gao Q,Liu M,Zhang S,Huang J,Jia R,Zhu D,Chen S,Zhao X,Yu Y,Liu Y,Zhang L,Tian B,Pan L
Fri Apr 30 00:00:00 EDT 2021
PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Scientific reports
Yue HW,Hong JY,Zhang SX,Jiang LL,Hu HY
Fri Apr 09 00:00:00 EDT 2021
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Toxicology and applied pharmacology
Geng Y,Wang Y,Sun R,Kang X,Zhao H,Zhu M,Sun Y,Hu Y,Wang Z,Tian X,Zhao Y,Yao J
Wed Dec 01 00:00:00 EST 2021
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
International immunopharmacology
Hong W,Zhi FX,Kun TH,Hua FJ,Huan Ling L,Fang F,Wen C,Jie W,Yang LC
Mon Mar 01 00:00:00 EST 2021
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Experimental cell research
Tan M,Meng J,Sun X,Fu X,Wang R
Fri Oct 01 00:00:00 EDT 2021
Peptides derived from viral glycoprotein Gc Inhibit infection of severe fever with thrombocytopenia syndrome virus.
Antiviral research
Gao C,Yu Y,Wen C,Li Z,Sun M,Gao S,Lin S,Wang S,Zou P,Xing Z
Fri Oct 01 00:00:00 EDT 2021
Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Neoplasia (New York, N.Y.)
Ha DP,Tsai YL,Lee AS
Wed Dec 01 00:00:00 EST 2021
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Journal for immunotherapy of cancer
Zhao S,Wang C,Lu P,Lou Y,Liu H,Wang T,Yang S,Bao Z,Han L,Liang X,Ma C,Gao L
Mon Nov 01 00:00:00 EDT 2021
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance.
Ecotoxicology and environmental safety
Zhang J,Qiu T,Jiang L,Wang N,Zhu Y,Yan R,Wang S,Bai J,Shi X,Yang G,Liu X,Yao X,Sun X
Fri Oct 15 00:00:00 EDT 2021
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
American journal of cancer research
Yan S,Li Q,Zhang D,Wang X,Xu Y,Zhang C,Guo D,Bao Y
Tue Jun 08 00:00:00 EDT 2021
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Nano convergence
Dong T,Jiang J,Zhang H,Liu H,Zou X,Niu J,Mao Y,Zhu M,Chen X,Li Z,Chen Y,Shi C,Yang X
Mon Oct 04 00:00:00 EDT 2021
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses.
Oxidative medicine and cellular longevity
Chen Y,Cui L,Wang C,Liu J,Guo J
Tue Jan 11 00:00:00 EST 2022
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Digestive diseases and sciences
Sun RF,Zhao CY,Chen S,Yu W,Zhou MM,Gao CR
Mon Mar 01 00:00:00 EST 2021
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Cancers
Schmitt BM,Boewe AS,Götz C,Philipp SE,Urbschat S,Oertel J,Menger MD,Laschke MW,Ampofo E
Fri Apr 02 00:00:00 EDT 2021
FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes.
International journal of biological sciences
Wang X,Dou N,Wang J,Zhang Y,Li Y,Gao Y
Fri Jan 21 00:00:00 EST 2022
High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury.
Neural regeneration research
Song HH,Song TC,Yang T,Sun CS,He BQ,Li H,Wang YJ,Li Y,Wu H,Hu YM,Wang YJ
Wed Sep 01 00:00:00 EDT 2021
Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.
Aging
Zheng Y,Niu B,Zhang W,Ru X,Gao Y,Li C,Wu X
Mon Oct 25 00:00:00 EDT 2021
miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
Molecular medicine reports
Wei W,Liu C,Yao R,Tan Q,Wang Q,Tian H
Mon Nov 01 00:00:00 EDT 2021
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
EMBO reports
Sun H,Li L,Li W,Yang F,Zhang Z,Liu Z,Du W
Tue Oct 05 00:00:00 EDT 2021
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
EMBO reports
Sun H,Li L,Li W,Yang F,Zhang Z,Liu Z,Du W
Tue Oct 05 00:00:00 EDT 2021
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
EMBO reports
Sun H,Li L,Li W,Yang F,Zhang Z,Liu Z,Du W
Tue Oct 05 00:00:00 EDT 2021
p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
EMBO reports
Sun H,Li L,Li W,Yang F,Zhang Z,Liu Z,Du W
Tue Oct 05 00:00:00 EDT 2021
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
The Journal of biological chemistry
King WT,Axelrod CL,Zunica ERM,Noland RC,Davuluri G,Fujioka H,Tandler B,Pergola K,Hermann GE,Rogers RC,López-Domènech S,Dantas WS,Stadler K,Hoppel CL,Kirwan JP
Fri Oct 01 00:00:00 EDT 2021
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Experimental cell research
Patki M,Saraswat A,Bhutkar S,Dukhande V,Patel K
Sun Aug 15 00:00:00 EDT 2021
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Theranostics
Liu W,Zhan Z,Zhang M,Sun B,Shi Q,Luo F,Zhang M,Zhang W,Hou Y,Xiao X,Li Y,Feng H
Wed Jul 28 00:00:00 EDT 2021
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Science advances
Lei Y,Guerra Martinez C,Torres-Odio S,Bell SL,Birdwell CE,Bryant JD,Tong CW,Watson RO,West LC,West AP
Sat May 01 00:00:00 EDT 2021
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Journal of experimental & clinical cancer research : CR
Chen Z,Wang H,Zhang Z,Xu J,Qi Y,Xue H,Gao Z,Zhao R,Wang S,Zhang S,Qiu W,Guo X,Li G
Thu Jan 07 00:00:00 EST 2021
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Journal of the American Heart Association
Huang Y,Li L,Chen H,Liao Q,Yang X,Yang D,Xia X,Wang H,Wang WE,Chen L,Zeng C
Tue Nov 02 00:00:00 EDT 2021
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
Nature metabolism
Schwartz AJ,Goyert JW,Solanki S,Kerk SA,Chen B,Castillo C,Hsu PP,Do BT,Singhal R,Dame MK,Lee HJ,Spence JR,Lakhal-Littleton S,Vander Heiden MG,Lyssiotis CA,Xue X,Shah YM
Thu Jul 01 00:00:00 EDT 2021
Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis.
Mediators of inflammation
Fu Y,Shen J,Li Y,Liu F,Ning B,Zheng Y,Jiang X
Mon Mar 28 00:00:00 EDT 2022
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Frontiers in endocrinology
Zhang J,Yang P,Liu D,Gao M,Wang J,Wang X,Liu Y,Zhang X
Wed Dec 22 00:00:00 EST 2021
α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular-mitral synaptic transmission.
NPJ Parkinson's disease
Chen F,Liu W,Liu P,Wang Z,Zhou Y,Liu X,Li A
Mon Dec 13 00:00:00 EST 2021
The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
Frontiers in immunology
Wang Z,Mo Y,Tan Y,Wen Z,Dai Z,Zhang H,Zhang X,Feng S,Liang X,Song T,Cheng Q
Mon Feb 28 00:00:00 EST 2022
Synergism of HPV and MNNG repress miR-218 promoting Het-1A cell malignant transformation by targeting GAB2.
Toxicology
Zhang Y,Zheng Y,Pan E,Zhao C,Zhang H,Liu R,Wang S,Pu Y,Yin L
Fri Jan 15 00:00:00 EST 2021
The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Cell death & disease
Jin R,Zhao A,Han S,Zhang D,Sun H,Li M,Su D,Liang X
Wed Oct 13 00:00:00 EDT 2021
H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
Medical oncology (Northwood, London, England)
Chen J,Jin X,Shen Z,Mei Y,Zhu J,Zhang X,Liang G,Zheng X
Wed Apr 21 00:00:00 EDT 2021
LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.
Experimental cell research
Sun X,Wang R,Tan M,Tian X,Meng J
Sun Aug 01 00:00:00 EDT 2021
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Cell
Wang LL,Serrano C,Zhong X,Ma S,Zou Y,Zhang CL
Thu Oct 14 00:00:00 EDT 2021
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Cell death & disease
Chang H,Xu Q,Li J,Li M,Zhang Z,Ma H,Yang X
Wed Jul 21 00:00:00 EDT 2021
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Bioorganic chemistry
Liang Y,Zhang M,Zhou P,Liu M,Li J,Wang Y
Fri Oct 01 00:00:00 EDT 2021
Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.
Pediatric research
Huang F,Zhu P,Wang J,Chen J,Lin W
Fri Jan 01 00:00:00 EST 2021
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Cell death & disease
Yan Y,Zhou Y,Li J,Zheng Z,Hu Y,Li L,Wu W
Thu Oct 07 00:00:00 EDT 2021
DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease.
Journal of cellular and molecular medicine
Dong X,Cong S
Wed Sep 01 00:00:00 EDT 2021
Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.
Environmental science and pollution research international
Tan J,Sun M,Luo Q,Sun H,Wang M,Jiang C,Li S,He Y
Fri Jan 01 00:00:00 EST 2021
Calcitriol Alleviates MPP+- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Frontiers in aging neuroscience
Hu J,Wu J,Wan F,Kou L,Yin S,Sun Y,Li Y,Zhou Q,Wang T
Tue Aug 17 00:00:00 EDT 2021
Chitotriosidase attenuates brain inflammation via HDAC3/NF-κB pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Neuroscience research
Yu X,Yu W,Wu L,Yang W,Lü Y
Mon Nov 01 00:00:00 EDT 2021
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.
Aging
Zeng Y,Huang T,Zuo W,Wang D,Xie Y,Wang X,Xiao Z,Chen Z,Liu Q,Liu N,Xiao Y
Mon Jul 26 00:00:00 EDT 2021
UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.
Journal of ovarian research
Hu W,Li M,Chen Y,Gu X
Fri Sep 17 00:00:00 EDT 2021
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte.
Frontiers in endocrinology
Dai L,Xie Y,Zhang W,Zhong X,Wang M,Jiang H,He Z,Liu X,Zeng H,Wang H
Thu Feb 10 00:00:00 EST 2022
Circ11103 Interacts with miR-128/PPARGC1A to Regulate Milk Fat Metabolism in Dairy Cows.
Journal of agricultural and food chemistry
Chen Z,Lu Q,Liang Y,Cui X,Wang X,Mao Y,Yang Z
Wed Apr 21 00:00:00 EDT 2021
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer.
Frontiers in oncology
Hong Q,Li B,Cai X,Lv Z,Cai S,Zhong Y,Wen B
Tue Aug 31 00:00:00 EDT 2021
Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/AKT signaling pathway.
Bioengineered
Niu Z,Li Y,Xu Y,Jiang W,Tao R,Chen Y,Han Y
Wed Dec 01 00:00:00 EST 2021
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Zhao ZW,Zhang M,Liao LX,Zou J,Wang G,Wan XJ,Zhou L,Li H,Qin YS,Yu XH,Tang CK
Sat May 01 00:00:00 EDT 2021
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Q,Zhang F,Liu S,Jiang Y,Ouyang D
Sun Aug 01 00:00:00 EDT 2021
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Nature cell biology
Gao N,Hu J,He B,Ji Z,Hu X,Huang J,Wei Y,Peng J,Wei Y,Zhou Y,Shen X,Li H,Feng X,Xiao Q,Shi L,Sun Y,Zhou C,Zhou H,Yang H
Fri Jan 01 00:00:00 EST 2021
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li C,Shen Y,Huang L,Liu C,Wang J
Fri Jan 01 00:00:00 EST 2021
Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice.
Redox biology
An D,Zeng Q,Zhang P,Ma Z,Zhang H,Liu Z,Li J,Ren H,Xu D
Fri Oct 01 00:00:00 EDT 2021
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Li R,Li W,He F,Zhang M,Luo H,Tang H
Fri Oct 01 00:00:00 EDT 2021
Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction.
Journal of biochemical and molecular toxicology
Wang J,Wang Y,He S,Wang Z,Deng Q,Liang H
Mon Nov 01 00:00:00 EDT 2021
Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia.
Molecular therapy. Methods & clinical development
May FJ,Head PE,Venturoni LE,Chandler RJ,Venditti CP
Fri Jun 11 00:00:00 EDT 2021
Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein-Barr virus infection.
The Journal of biological chemistry
Dai DL,Li X,Wang L,Xie C,Jin Y,Zeng MS,Zuo Z,Xia TL
Mon Aug 23 00:00:00 EDT 2021
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer.
BioMed research international
Liu S,He L,Sheng C,Su R,Wu X,Sun Y,Xi X
Wed Sep 22 00:00:00 EDT 2021
ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
eLife
Tian M,Hao F,Jin X,Sun X,Jiang Y,Wang Y,Li D,Chang T,Zou Y,Peng P,Xia C,Liu J,Li Y,Wang P,Feng Y,Wei M
Tue Sep 07 00:00:00 EDT 2021
iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis.
Acta biochimica et biophysica Sinica
Yagudin T,Zhao Y,Gao H,Zhang Y,Yang Y,Zhang X,Ma W,Daba TM,Ishmetov V,Kang K,Yang B,Pan Z
Tue Jan 12 00:00:00 EST 2021
LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication.
Journal of experimental & clinical cancer research : CR
Sheng X,Dai H,Du Y,Peng J,Sha R,Yang F,Zhou L,Lin Y,Xu S,Wu Y,Yin W,Lu J
Wed Jun 23 00:00:00 EDT 2021
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
Zhu B,Chen JJ,Feng Y,Yang JL,Huang H,Chung WY,Hu YL,Xue WJ
Mon Nov 08 00:00:00 EST 2021
Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.
Frontiers in oncology
Chen H,Zu F,Zeng T,Chen Z,Wei J,Liu P,Li Z,Zhou L,Wang H,Tan H,Tan X
Sun May 01 00:00:00 EDT 2022
Mutations in GDAP1 Influence Structure and Function of the Trans-Golgi Network.
International journal of molecular sciences
Binięda K,Rzepnikowska W,Kolakowski D,Kaminska J,Szczepankiewicz AA,Nieznańska H,Kochański A,Kabzińska D
Mon Jan 18 00:00:00 EST 2021
Evaluating the protective effects of individual or combined ginsenoside compound K and the downregulation of soluble epoxide hydrolase expression against sodium valproate-induced liver cell damage.
Toxicology and applied pharmacology
Zhou L,Zeng X,Rao T,Tan Z,Zhou G,Ouyang D,Chen L
Thu Jul 01 00:00:00 EDT 2021
The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy.
Cell death & disease
Huang T,Li X,Wang F,Lu L,Hou W,Zhu M,Miao C
Mon Mar 29 00:00:00 EDT 2021
JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
International immunopharmacology
He J,Liu T,Li Y,Mi X,Han D,Yang N,Chen L,Li Y,Hong J,Kuang C,Yuan Y,Cao Y,Han Y,Shi C,Li Z,Guo X
Fri Oct 01 00:00:00 EDT 2021
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway.
Neuroscience
Wu X,Wang J,Song L,Guan Y,Cao C,Cui Y,Zhang Y,Liu C
Fri Oct 01 00:00:00 EDT 2021
An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
International journal of molecular sciences
Yu S,Yan X,Tian R,Xu L,Zhao Y,Sun L,Su J
Tue Apr 13 00:00:00 EDT 2021
NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis.
International journal of biological sciences
Tian J,Xiao Z,Wei J,Shan Y,Zeng D,Tao Y,Fang X,Tang C,Chen X,Li Y
Fri Mar 18 00:00:00 EDT 2022
MiRNA-132/212 regulates tight junction stabilization in blood-brain barrier after stroke.
Cell death discovery
Yan H,Kanki H,Matsumura S,Kawano T,Nishiyama K,Sugiyama S,Takemori H,Mochizuki H,Sasaki T
Wed Dec 08 00:00:00 EST 2021
Down-regulation of A3AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Experimental cell research
Hu S,Guo P,Wang Z,Zhou Z,Wang R,Zhang M,Tao J,Tai Y,Zhou W,Wei W,Wang Q
Mon Feb 15 00:00:00 EST 2021
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Toxicology
Mondal A,Saha P,Bose D,Chatterjee S,Seth RK,Xiao S,Porter DE,Brooks BW,Scott GI,Nagarkatti M,Nagarkatti P,Chatterjee S
Wed Sep 01 00:00:00 EDT 2021
Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB.
Zeitschrift fur Naturforschung. C, Journal of biosciences
Xu W,Kusano J,Chen S,Yamamoto R,Matsuda H,Hara Y,Fujii Y,Hayashi S,Tanaka S,Sugiyama K,Yamada H,Hirano T
Wed Jan 27 00:00:00 EST 2021
Arsenic (III) induces oxidative stress and inflammation in the gills of common carp, which is ameliorated by zinc (II).
Journal of inorganic biochemistry
Lu H,Zhao H,Wang Y,Guo M,Mu M,Liu Y,Nie X,Huang P,Xing M
Wed Dec 01 00:00:00 EST 2021
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Frontiers in cardiovascular medicine
Li Y,Xie KF,Chang YH,Wang C,Chen Y,Wang MJ,Zhu YC
Tue Oct 05 00:00:00 EDT 2021
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Environmental toxicology
Xu H,Liu T,Li W,Yao Q
Tue Jun 01 00:00:00 EDT 2021
Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.
Frontiers in cell and developmental biology
Zeng L,Zhou J,Zhang Y,Wang X,Wang M,Su P
Fri Jan 21 00:00:00 EST 2022
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Journal of molecular neuroscience : MN
Chibaatar E,Le K,Abdoulaye IA,Wu S,Guo Y
Thu Apr 01 00:00:00 EDT 2021
Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Kidney360
Miyazaki-Anzai S,Masuda M,Shiozaki Y,Keenan AL,Chonchol M,Kremoser C,Miyazaki M
Sat May 01 00:00:00 EDT 2021
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Science advances
Cheng J,Dong Y,Ma J,Pan R,Liao Y,Kong X,Li X,Li S,Chen P,Wang L,Yu Y,Yuan Z
Sun Aug 01 00:00:00 EDT 2021
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Biochemical and biophysical research communications
Lu C,Wu B,Liao Z,Xue M,Zou Z,Feng J,Sheng J
Fri Jun 25 00:00:00 EDT 2021
Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Li B,Zhao J,Ma J,Chen W,Zhou C,Wei W,Li S,Li G,Xin G,Zhang Y,Liu J,Wang Y,Ma X
Sat May 01 00:00:00 EDT 2021
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.
Journal of medicinal chemistry
Qin X,Chen H,Tu L,Ma Y,Liu N,Zhang H,Li D,Riedl B,Bierer D,Yin F,Li Z
Thu Sep 23 00:00:00 EDT 2021
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Animals : an open access journal from MDPI
Mohammadi-Aragh MK,Stokes CE,Street JT,Linhoss JE
Mon Jul 26 00:00:00 EDT 2021
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Microorganisms
Chen S,Li Y,Chu B,Yuan L,Liu N,Zhu Y,Wang J
Fri Sep 17 00:00:00 EDT 2021
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke.
Evidence-based complementary and alternative medicine : eCAM
Wang C,Chen H,Ma ST,Mao BB,Chen Y,Xu HN,Yu H
Tue Apr 26 00:00:00 EDT 2022
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Molecular neurobiology
Liu H,Chen B,Guo B,Deng X,Wang B,Dou X
Wed Sep 01 00:00:00 EDT 2021
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
International journal of biological macromolecules
Yang Z,Ouyang T,Aoyagi H,Wang T,Xing X,Zhang Y,Wang Y,Li Y,Aizaki H,Li S,Kong L
Fri Oct 01 00:00:00 EDT 2021
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Clinical & experimental metastasis
Shi X,Huang X,Chen R,Li Y,Xu Y,Zhang W,Zhu Q,Zha X,Wang J
Wed Dec 01 00:00:00 EST 2021
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Clinical & experimental metastasis
Shi X,Huang X,Chen R,Li Y,Xu Y,Zhang W,Zhu Q,Zha X,Wang J
Wed Dec 01 00:00:00 EST 2021
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Frontiers in pharmacology
Li T,Jiang G,Hu X,Yang D,Tan T,Gao Z,Chen Z,Xiang C,Li S,Ouyang Z,Guo X
Tue Dec 07 00:00:00 EST 2021
Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model.
Frontiers in immunology
Jin BY,Li Z,Xia YN,Li LX,Zhao ZX,Li XY,Li Y,Li B,Zhou RC,Fu SC,Li SY,Li YQ
Wed Jan 05 00:00:00 EST 2022
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Ecotoxicology and environmental safety
Yu FF,Zuo J,Fu X,Gao MH,Sun L,Yu SY,Li Z,Zhou GY,Ba Y
Wed Dec 01 00:00:00 EST 2021
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Bioorganic & medicinal chemistry
Zhao T,Yang Y,Yang J,Cui Y,Cao Z,Zuo D,Zhai X
Wed Sep 15 00:00:00 EDT 2021
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR(+/-) hamsters.
Lipids in health and disease
Yu WQ,Yin F,Shen N,Lin P,Xia B,Li YJ,Guo SD
Mon Dec 13 00:00:00 EST 2021
Inhibition of miR-96-5p May Reduce Aβ42/Aβ40 Ratio via Regulating ATP-binding cassette transporter A1.
Journal of Alzheimer's disease : JAD
Zhu M,Jia L,Jia J
Fri Nov 26 00:00:00 EST 2021
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Nature
Wang Q,Li D,Cao G,Shi Q,Zhu J,Zhang M,Cheng H,Wen Q,Xu H,Zhu L,Zhang H,Perry RJ,Spadaro O,Yang Y,He S,Chen Y,Wang B,Li G,Liu Z,Yang C,Wu X,Zhou L,Zhou Q,Ju Z,Lu H,Xin Y,Yang X,Wang C,Liu Y,Shulman GI,Dixit VD,Lu L,Yang H,Flavell RA,Yin Z
Wed Dec 01 00:00:00 EST 2021
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Cancer science
Guo K,Wang P,Zhang L,Zhou Y,Dai X,Yan Y,Chen Y,Wasan HS,Yu J,Ruan S,Sun L
Fri Oct 01 00:00:00 EDT 2021
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Frontiers in cell and developmental biology
Gui Z,Zhao Z,Sun Q,Shao G,Huang J,Zhao W,Kuang Y
Fri Nov 19 00:00:00 EST 2021
TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71.
Virologica Sinica
Wo X,Yuan Y,Xu Y,Chen Y,Wang Y,Zhao S,Lin L,Zhong X,Wang Y,Zhong Z,Zhao W
Mon Feb 01 00:00:00 EST 2021
High Methionine Diet-Induced Alzheimer's Disease like Symptoms Are Accompanied by 5-Methylcytosine Elevated Levels in the Brain.
Behavioural neurology
Pi T,Wei S,Jiang Y,Shi JS
Wed Aug 18 00:00:00 EDT 2021
Diacerein attenuates vascular dysfunction by reducing inflammatory response and insulin resistance in type 2 diabetic rats.
Biochemical and biophysical research communications
He A,Shen J,Xue Y,Li Y,Huang L,Lv D,Luo M
Fri Dec 31 00:00:00 EST 2021
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Li H,Zhao K,Li Y
Tue Mar 09 00:00:00 EST 2021
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Neurochemistry international
Xiao H,Jiang Q,Qiu H,Wu K,Ma X,Yang J,Cheng O
Mon Nov 01 00:00:00 EDT 2021
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Biomedicines
Yu M,Hu X,Yan J,Wang Y,Lu F,Chang J
Fri Sep 17 00:00:00 EDT 2021
GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Evidence-based complementary and alternative medicine : eCAM
Huang H,Chen Z,Li Y,Gong K,Xiao L,Fu H,Yang J,Wang X,Meng Q
Tue Sep 21 00:00:00 EDT 2021
The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ming J,Liu W,Wu H,Li Y,Yang E,Wang Z,Xiao H,Quan R,Hu X
Sun Aug 01 00:00:00 EDT 2021
METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.
Journal of hazardous materials
Yuan Q,Zhu H,Liu H,Wang M,Chu H,Zhang Z
Thu Aug 05 00:00:00 EDT 2021
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dong Z,Qiu T,Zhang J,Sha S,Han X,Kang J,Shi X,Sun X,Jiang L,Yang G,Yao X,Ma Y
Mon Nov 01 00:00:00 EDT 2021
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Frontiers in genetics
Yang L,Li L,Chang P,Wei M,Chen J,Zhu C,Jia J
Sat Nov 13 00:00:00 EST 2021
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Food chemistry
Wang Y,Jin R,Chen J,Cao J,Xiao J,Li X,Sun C
Wed Dec 15 00:00:00 EST 2021
Suppressors of cytokine signaling 1 protein in a regenerative model of the Gekko japonicus spinal cord.
Journal of integrative neuroscience
He B,Wang W,Sun C,Yang T,Li H,Chen X,Liang H,Song H,Wang Y,Wang Y
Thu Sep 30 00:00:00 EDT 2021
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Human cell
Li J,Shao W,Zhao J
Mon Mar 01 00:00:00 EST 2021
miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models.
Genes to cells : devoted to molecular & cellular mechanisms
Wang R,Yao J,Gong F,Chen S,He Y,Hu C,Li C
Wed Sep 01 00:00:00 EDT 2021
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Frontiers in oncology
Tan L,Tang Y,Li H,Li P,Ye Y,Cen J,Gui C,Luo J,Cao J,Wei J
Sat Jun 26 00:00:00 EDT 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 EDT 2021
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Cell proliferation
Chen Y,Sun J,Ju Z,Wang ZQ,Li T
Mon Mar 01 00:00:00 EST 2021
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
The European journal of neuroscience
Huang L,Liu Z,Yuan Y,Shen L,Jiang H,Tang B,Wang J,Lei L
Mon Feb 01 00:00:00 EST 2021
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Yan X,Qu X,Liu B,Zhao Y,Xu L,Yu S,Wang J,Wang L,Su J
Tue Dec 07 00:00:00 EST 2021
ERK1/2 mitogen-activated protein kinase mediates downregulation of intestinal tight junction proteins in heat stress-induced IBD model in pig.
Journal of thermal biology
Yong Y,Li J,Gong D,Yu T,Wu L,Hu C,Liu X,Yu Z,Ma X,Gooneratne R,Abd El-Aty AM,Chen J,Ju X
Fri Oct 01 00:00:00 EDT 2021
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
Animals : an open access journal from MDPI
Yang X,Xing F,Wang L,Zhao W,Fu Y,Tu F,Li B,Fang X,Ren S
Sat Jan 30 00:00:00 EST 2021
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
Parasites & vectors
Yue TT,Zhang N,Li JH,Lu XY,Wang XC,Li X,Zhang HB,Cheng SQ,Wang BB,Gong PT,Zhang XC
Sun Sep 26 00:00:00 EDT 2021
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
Biology direct
Zhang Y,Li S,Li F,Lv C,Yang QK
Mon May 31 00:00:00 EDT 2021
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan S,Liu X,Wang Y,Ren X,Liu Y,Dong Y,Fan Q,Wei J,Ma J,Yu A,Song R,Sui H,Shen M,Fang F,Xia Q,She G
Fri Oct 01 00:00:00 EDT 2021
Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazid.
Nature communications
Jiang Y,Li Y,Liu C,Zhang L,Lv D,Weng Y,Cheng Z,Chen X,Zhan J,Zhang H
Mon Sep 20 00:00:00 EDT 2021
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Acta biomaterialia
Meng X,Wang J,Zhou J,Tian Q,Qie B,Zhou G,Duan W,Zhu Y
Tue Jun 01 00:00:00 EDT 2021
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.
FEBS open bio
Jin Y,Chen Z,Dong J,Wang B,Fan S,Yang X,Cui M
Sat May 01 00:00:00 EDT 2021
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Biochemical and biophysical research communications
Ge W,Chen Y,Guo Y,Zhao D,Mu L,Zhang K,Zhuo W
Fri Sep 17 00:00:00 EDT 2021
Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions.
Cells, tissues, organs
Kurihara M,Mukudai Y,Watanabe H,Asakura M,Abe Y,Houri A,Chikuda J,Shimane T,Shirota T
Mon Jan 17 00:00:00 EST 2022
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Frontiers in pharmacology
Rong Q,Han B,Li Y,Yin H,Li J,Hou Y
Tue Jan 25 00:00:00 EST 2022
Nervous Necrosis Virus Coat Protein Mediates Host Translation Shutoff through Nuclear Translocalization and Degradation of Polyadenylate Binding Protein.
Journal of virology
Cheng CA,Luo JM,Chiang MH,Fang KY,Li CH,Chen CW,Wang YS,Chang CY
Tue Aug 10 00:00:00 EDT 2021
Milk Polar Lipids Supplementation to Obese Rats During Pregnancy and Lactation Benefited Skeletal Outcomes of Male Offspring.
Molecular nutrition & food research
Han L,Du M,Ren F,Mao X
Sun Aug 01 00:00:00 EDT 2021
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
International journal of biological sciences
Chen X,Sun N,Li R,Sang X,Li X,Zhao J,Han J,Yang J,Ikezoe T
Thu Mar 24 00:00:00 EDT 2022
FMR1/circCHAF1A/miR-211-5p/HOXC8 feedback loop regulates proliferation and tumorigenesis via MDM2-dependent p53 signaling in GSCs.
Oncogene
Jiang Y,Wang Z,Ying C,Hu J,Zeng T,Gao L
Tue Jun 01 00:00:00 EDT 2021
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture.
Virulence
Zhao Y,Jiang S,Zhang J,Guan XL,Sun BG,Sun L
Wed Dec 01 00:00:00 EST 2021
Transcriptomic-based toxicological investigations of graphene oxide with modest cytotoxicity to human umbilical vein endothelial cells: changes of Toll-like receptor signaling pathways.
Toxicology research
Luo Y,Wang X,Cao Y
Wed Dec 01 00:00:00 EST 2021
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Cell death & disease
Wan X,Zhu L,Zhao L,Peng L,Xiong J,Yang W,Yuan J,Liang F,Zhang K,Chen K
Fri Mar 19 00:00:00 EDT 2021
Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.
International journal of biological macromolecules
Hou Z,Shi W,Feng J,Wang W,Zheng E,Lin H,Yu C,Li L
Wed Jun 30 00:00:00 EDT 2021
Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Journal of Cancer
Liao X,Zhang Y,Xu B,Ali A,Liu X,Jia Q
Tue Sep 21 00:00:00 EDT 2021
Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.
Frontiers in pharmacology
Hu J,Chen R,An J,Wang Y,Liang M,Huang K
Mon Sep 04 00:00:00 EDT 2023
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
JCI insight
Hu W,Liu Z,Salato V,North PE,Bischoff J,Kumar SN,Fang Z,Rajan S,Hussain MM,Miao QR
Mon Feb 08 00:00:00 EST 2021
Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations.
Cell reports
Gil-Ranedo J,Gallego-García C,Almendral JM
Tue Sep 07 00:00:00 EDT 2021
ITGA5 Predicts Dual-Drug Resistance to Temozolomide and Bevacizumab in Glioma.
Frontiers in oncology
Shi Y,Wu M,Liu Y,Hu L,Wu H,Xie L,Liu Z,Wu A,Chen L,Xu C
Wed Nov 08 00:00:00 EST 2023
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells.
Journal of medicinal chemistry
Cao S,Ma L,Liu Y,Wei M,Yao Y,Li C,Wang R,Liu N,Dong Z,Li X,Li M,Wang X,Yang C,Yang G
Thu Nov 25 00:00:00 EST 2021
Growth Hormone Receptor (Ghr) 6ω Pseudoexon Activation: A Novel Cause Of Severe Growth Hormone Insensitivity (Ghi).
The Journal of clinical endocrinology and metabolism
Cottrell E,Maharaj A,Williams J,Chatterjee S,Cirillo G,Miraglia Del Giudice E,Festa A,Palumbo S,Capalbo D,Salerno M,Pignata C,Savage MO,Schilbach K,Bidlingmaier M,Hwa V,Metherell LA,Grandone A,Storr HL
Wed Jul 28 00:00:00 EDT 2021
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Chang XM,Xiao F,Pan Q,Wang XX,Guo LX
Wed Sep 01 00:00:00 EDT 2021
Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity.
The Journal of clinical endocrinology and metabolism
Cottrell E,Maharaj A,Williams J,Chatterjee S,Cirillo G,Miraglia Del Giudice E,Festa A,Palumbo S,Capalbo D,Salerno M,Pignata C,Savage MO,Schilbach K,Bidlingmaier M,Hwa V,Metherell LA,Grandone A,Storr HL
Wed Jul 28 00:00:00 EDT 2021
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Ecotoxicology and environmental safety
Wang L,Bao S,Liu X,Wang F,Zhang J,Dang P,Wang F,Li B,Lin Y
Mon Nov 01 00:00:00 EDT 2021
A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy.
Frontiers in molecular biosciences
Wang Y,Zhang J,Lin Y,Cheng S,Wang D,Rao M,Jiang Y,Huang X,Chen R,Xie Y,Yin P,Cheng B
Sat Mar 05 00:00:00 EST 2022
The CCAAT-binding complex mediates azole susceptibility of Aspergillus fumigatus by suppressing SrbA expression and cleavage.
MicrobiologyOpen
Zhang C,Gao L,Ren Y,Gu H,Zhang Y,Lu L
Mon Nov 01 00:00:00 EDT 2021
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Microorganisms
Yuan L,Chu B,Chen S,Li Y,Liu N,Zhu Y,Zhou D
Tue Nov 16 00:00:00 EST 2021
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
FEBS open bio
Shi Z,Wu D,Xu H,Yang J,Sun X
Sun Aug 01 00:00:00 EDT 2021
SARS-CoV-2 Host Receptor ACE2 Protein Expression Atlas in Human Gastrointestinal Tract.
Frontiers in cell and developmental biology
An X,Lin W,Liu H,Zhong W,Zhang X,Zhu Y,Wang X,Li J,Sheng Q
Sun Apr 24 00:00:00 EDT 2022
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan L,Peng Y,Wang J,Ma P,Zhao L,Li X
Mon Mar 01 00:00:00 EST 2021
Expression of lncRNA CCAT2 in children with neuroblastoma and its effect on cancer cell growth.
Molecular and cellular biochemistry
Chen M,Zhao M,Hou Y,Zhu B
Thu Apr 01 00:00:00 EDT 2021
MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
Journal of biomedical science
Li TT,Mou J,Pan YJ,Huo FC,Du WQ,Liang J,Wang Y,Zhang LS,Pei DS
Mon Aug 02 00:00:00 EDT 2021
A systematic approach to decode the mechanism of Cornus in the treatment of hepatocellular carcinoma (HCC).
European journal of pharmacology
Shen HY,Li XQ,Fan WQ,Wang YW,Huang F,Wu JQ,Zhang W,Feng XS,Chao X
Fri Oct 15 00:00:00 EDT 2021
Chondrocyte ferroptosis contribute to the progression of osteoarthritis.
Journal of orthopaedic translation
Yao X,Sun K,Yu S,Luo J,Guo J,Lin J,Wang G,Guo Z,Ye Y,Guo F
Mon Mar 01 00:00:00 EST 2021
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Translational lung cancer research
Tian Y,Li P,Xiao Z,Zhou J,Xue X,Jiang N,Peng C,Wu L,Tian H,Popper H,Poh ME,Marcucci F,Zhang C,Zhao X
Mon Feb 01 00:00:00 EST 2021
Kisspeptin-10 Maintains the Activation of the mTOR Signaling Pathway by Inhibiting SIRT6 to Promote the Synthesis of Milk in Bovine Mammary Epithelial Cells.
Journal of agricultural and food chemistry
Cao Y,Hu G,Zhang Q,Ma L,Wang J,Li W,Ge Y,Cheng J,Yang Z,Fu S,Liu J
Wed Apr 14 00:00:00 EDT 2021
In Vivo Inhibition of MicroRNA-326 in a NOD.H-2h4 Mouse Model of Autoimmune Thyroiditis.
Frontiers in immunology
Zhao N,Wang Z,Cui X,Wang S,Fan C,Li Y,Shan Z,Teng W
Fri Jun 25 00:00:00 EDT 2021
H. pylori infection induces CXCL8 expression and promotes gastric cancer progress through downregulating KLF4.
Molecular carcinogenesis
Liu Z,Wu X,Tian Y,Zhang W,Qiao S,Xu W,Liu Y,Wang S
Sun Aug 01 00:00:00 EDT 2021
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway.
BioMed research international
Zhu G,Liu J,Wang Y,Jia N,Wang W,Zhang J,Liang Y,Tian H,Zhang J
Tue Jan 25 00:00:00 EST 2022
Melatonin mediates monochromatic light-induced expression of somatostatin in the hypothalamus and pituitary of chicks.
Poultry science
Qin X,Liu X,Yan X,Long M,Wang Z,Dong Y,Chen Y,Cao J
Sun Aug 01 00:00:00 EDT 2021
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.
Brain research bulletin
Song L,Wu X,Wang J,Guan Y,Zhang Y,Gong M,Wang Y,Li B
Wed Dec 01 00:00:00 EST 2021
MIF promotes neurodegeneration and cell death via its nuclease activity following traumatic brain injury.
Cellular and molecular life sciences : CMLS
Ruan Z,Lu Q,Wang JE,Zhou M,Liu S,Zhang H,Durvasula A,Wang Y,Wang Y,Luo W,Wang Y
Sat Dec 18 00:00:00 EST 2021
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
Toxicology and applied pharmacology
Liu X,Wang Z,Wang X,Yan X,He Q,Liu S,Ye M,Li X,Yuan Z,Wu J,Yi J,Wen L,Li R
Wed Dec 01 00:00:00 EST 2021
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Molecular carcinogenesis
Li Y,Zhu X,Yang M,Wang Y,Li J,Fang J,Guo W,Ma S,Guan F
Thu Jul 01 00:00:00 EDT 2021
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.
PloS one
Nafie E,Lolarga J,Lam B,Guo J,Abdollahzadeh E,Rodriguez S,Glackin C,Liu J
Wed Aug 25 00:00:00 EDT 2021
HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression.
Biochemical and biophysical research communications
Zeng Z,Shi Z,Liu Y,Zhao J,Lu Q,Guo J,Liu X,Huang D,Xu Q
Fri Aug 20 00:00:00 EDT 2021
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Food & function
Yang JJ,Wang YH,Yin J,Leng H,Shen SD
Mon Aug 02 00:00:00 EDT 2021
Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer.
Cancer cell international
Chen J,Wang Z,Gao S,Wu K,Bai F,Zhang Q,Wang H,Ye Q,Xu F,Sun H,Lu Y,Liu Y
Thu Feb 25 00:00:00 EST 2021
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Blood cancer journal
Qiao X,Ma J,Knight T,Su Y,Edwards H,Polin L,Li J,Kushner J,Dzinic SH,White K,Wang J,Lin H,Wang Y,Wang L,Wang G,Taub JW,Ge Y
Mon Jun 07 00:00:00 EDT 2021
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Journal of cellular and molecular medicine
Liu S,Hu J,Shi C,Sun L,Yan W,Song Y
Tue Jun 01 00:00:00 EDT 2021
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice.
International journal of molecular medicine
Wang L,Ding J,Zhu C,Guo B,Yang W,He W,Li X,Wang Y,Li W,Wang F,Sun T
Wed Dec 01 00:00:00 EST 2021
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology in Gulf War Illness by Modulating Bacteriome-Virome Associated Inflammation and Microglia-Neuron Proinflammatory Crosstalk.
Brain sciences
Saha P,Skidmore PT,Holland LA,Mondal A,Bose D,Seth RK,Sullivan K,Janulewicz PA,Horner R,Klimas N,Nagarkatti M,Nagarkatti P,Lim ES,Chatterjee S
Fri Jul 09 00:00:00 EDT 2021
Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo.
Frontiers in pharmacology
Wu Y,You X,Lin Q,Xiong W,Guo Y,Huang Z,Dai X,Chen Z,Mei S,Long Y,Tian X,Zhou Q
Tue Mar 29 00:00:00 EDT 2022
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68.
Virology journal
Si J,Tang X,Xu L,Fu H,Li H,He Y,Bao J,Tang J,Li A,Lu N,Yang C
Sun Nov 07 00:00:00 EDT 2021
Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.
Breast cancer research and treatment
Lin Y,Lin L,Fu F,Wang C,Hu A,Xie J,Jiang M,Wang Z,Yang L,Guo R,Yang P,Shen H
Fri Jan 01 00:00:00 EST 2021
Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Nucleic acids research
Wang H,Shan X,Ren M,Shang M,Zhou C
Thu Dec 02 00:00:00 EST 2021
Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Frontiers in immunology
Renrick AN,Thounaojam MC,de Aquino MTP,Chaudhuri E,Pandhare J,Dash C,Shanker A
Mon Jun 28 00:00:00 EDT 2021
Icariin attenuates renal fibrosis in chronic kidney disease by inhibiting interleukin-1β/transforming growth factor-β-mediated activation of renal fibroblasts.
Phytotherapy research : PTR
Wang M,Wang L,Zhou Y,Feng X,Ye C,Wang C
Mon Nov 01 00:00:00 EDT 2021
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
EMBO reports
Wu G,Suo C,Yang Y,Shen S,Sun L,Li ST,Zhou Y,Yang D,Wang Y,Cai Y,Wang N,Zhang H,Yang YG,Cao J,Gao P
Wed Mar 03 00:00:00 EST 2021
Thioredoxin-1 Rescues MPP+/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4.
Molecular neurobiology
Bai L,Yan F,Deng R,Gu R,Zhang X,Bai J
Thu Jul 01 00:00:00 EDT 2021
Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology.
BioMed research international
Zhan L,Pu J,Hu Y,Xu P,Liang W,Ji C
Wed May 26 00:00:00 EDT 2021
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Biochemical and biophysical research communications
Wang N,Li J,Xin Q,Xu N
Fri Dec 03 00:00:00 EST 2021
Establishment of a specific in vivo Cu(¿) reporting system based on metallothionein screening.
Metallomics : integrated biometal science
Ma M,Qiu B,Jin J,Wang J,Nie Y,Liang Y,Yu Z,Teng CB
Fri Jul 02 00:00:00 EDT 2021
Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells.
In vitro cellular & developmental biology. Animal
Xu H,Zhang T,Hu X,Xie Y,Wu R,Lian S,Wang J
Sun Aug 01 00:00:00 EDT 2021
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
European journal of medicinal chemistry
Wang S,Yang H,Su M,Lian F,Cong Z,Wei R,Zhou Y,Li X,Zheng X,Li C,Fu X,Han X,Shi Q,Li C,Zhang N,Geng M,Liu H,Li J,Huang X,Wang J
Fri Oct 15 00:00:00 EDT 2021
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Molecules (Basel, Switzerland)
Chen C,Lv Q,Li Y,Jin YH
Sun Jun 27 00:00:00 EDT 2021
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
PloS one
Chen C,Huang X,Zhu W,Ding C,Huang P,Li R
Mon Nov 22 00:00:00 EST 2021
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Bioengineered
Yang J,Hu Y,Wang L,Sun X,Yu L,Guo W
Wed Dec 01 00:00:00 EST 2021
The Regulation of Staphylococcus aureus-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells.
Frontiers in veterinary science
Cai M,Fan W,Li X,Sun H,Dai L,Lei D,Dai Y,Liao Y
Sat Jun 19 00:00:00 EDT 2021
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Journal of cellular and molecular medicine
Gao L,Nie X,Gou R,Hu Y,Dong H,Li X,Lin B
Wed Dec 01 00:00:00 EST 2021
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Frontiers in medicine
Gu L,Ren F,Fang X,Yuan L,Liu G,Wang S
Tue Jul 13 00:00:00 EDT 2021
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Cell death discovery
Li D,Wang X,Li G,Dang Y,Zhao S,Qin Y
Sun May 16 00:00:00 EDT 2021
Arsenite induce neurotoxicity of common carp: Involvement of blood brain barrier, apoptosis and autophagy, and subsequently relieved by zinc (Ⅱ) supplementation.
Aquatic toxicology (Amsterdam, Netherlands)
Wang Y,Zhao H,Liu Y,Guo M,Tian Y,Huang P,Xing M
Mon Jan 25 00:00:00 EST 2021
Ex vivo to in vivo extrapolation of syringic acid and ferulic acid as grape juice proxies for endothelium-dependent vasodilation: Redefining vasoprotective resveratrol of the French paradox.
Food chemistry
Huang Y,Xu M,Li J,Chen K,Xia L,Wang W,Ren P,Huang X
Tue Nov 30 00:00:00 EST 2021
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
Cellular and molecular gastroenterology and hepatology
Zhu Y,Zhao H,Lu J,Lin K,Ni J,Wu G,Tang H
Thu Jan 27 00:00:00 EST 2022
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression.
BMC biology
Shen T,Xia W,Min S,Yang Z,Cheng L,Wang W,Zhan Q,Shao F,Zhang X,Wang Z,Zhang Y,Shen G,Zhang H,Wu LL,Yu GY,Kong QP,Wang X
Tue Sep 07 00:00:00 EDT 2021
Identification of genes and pathways leading to metastasis and poor prognosis in melanoma.
Aging
Zhang X,Wang W,Wang Y,Jiang G
Tue Sep 28 00:00:00 EDT 2021
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Veterinary microbiology
Zhang L,Jin M,Song M,Liu S,Wang T,Guo K,Zhang Y
Thu Apr 01 00:00:00 EDT 2021
Thromboxane A2 is involved in the development of hypertension in chronic kidney disease rats.
European journal of pharmacology
Hu J,Yang Z,Chen X,Kuang S,Lian Z,Ke G,Liao R,Ma J,Li S,Zhang L,Li Z,Feng Z,Liang H,Lin T,Dong W,Li R,Li Z,Chen Y,Liang X,Shi W,Deng C,Liu S
Fri Oct 15 00:00:00 EDT 2021
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
European journal of pharmacology
Zhang J,Yan L,Wei P,Zhou R,Hua C,Xiao M,Tu Y,Gu Z,Wei T
Mon Mar 15 00:00:00 EDT 2021
MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression.
Toxicology letters
Chen J,Lai W,Deng Y,Liu M,Dong M,Liu Z,Wang T,Li X,Zhao Z,Yin X,Yang J,Yu R,Liu L
Thu Jul 01 00:00:00 EDT 2021
Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification.
Frontiers in physiology
Wang YM,Tan MY,Zhang RJ,Qiu MY,Fu YS,Xie XJ,Gu HF
Sun May 01 00:00:00 EDT 2022
Bone morphogenetic protein-7 inhibits endothelial-to-mesenchymal transition in primary human umbilical vein endothelial cells and mouse model of systemic sclerosis via Akt/mTOR/p70S6K pathway.
Journal of dermatological science
Shen C,Jiang Y,Li Q,Liu C,Hu F,Li M
Sun Aug 01 00:00:00 EDT 2021
Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis.
Frontiers in cell and developmental biology
Lv Z,Xiong LL,Qin X,Zhang H,Luo X,Peng W,Kilby MD,Saffery R,Baker PN,Qi HB
Sat Dec 18 00:00:00 EST 2021
In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.
Journal of oncology
Li X,An M,Gao Z
Wed Dec 15 00:00:00 EST 2021
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
Frontiers in cell and developmental biology
Guo B,Qi M,Huang S,Zhuo R,Zhang W,Zhang Y,Xu M,Liu M,Guan T,Liu Y
Fri Nov 26 00:00:00 EST 2021
Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons.
Frontiers in cell and developmental biology
Guo B,Qi M,Huang S,Zhuo R,Zhang W,Zhang Y,Xu M,Liu M,Guan T,Liu Y
Fri Nov 26 00:00:00 EST 2021
Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors' Transcription During Oocyte Growth.
Frontiers in cell and developmental biology
Yang W,Ma Y,Jin J,Ren P,Zhou H,Xu S,Zhang Y,Hu Z,Rong Y,Dai Y,Zhang Y,Zhang S
Fri Jun 25 00:00:00 EDT 2021
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Journal of food biochemistry
Xin C,Zhao M,Wang J,Wang Z
Thu Jul 01 00:00:00 EDT 2021
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
Aging
Ding J,Zhang R,Li H,Ji Q,Cheng X,Thorne RF,Hondermarck H,Liu X,Shen C
Tue Apr 06 00:00:00 EDT 2021
Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.
Cell reports
Kunisky AK,Anyaeche VI,Herron RS,Park CY,Hwang HW
Tue Oct 12 00:00:00 EDT 2021
Acquiring high expression of suilysin enable non-epidemic Streptococccus suis to cause streptococcal toxic shock-like syndrome (STSLS) through NLRP3 inflammasome hyperactivation.
Emerging microbes & infections
Xu L,Lin L,Lu X,Xiao P,Liu R,Wu M,Jin M,Zhang A
Wed Dec 01 00:00:00 EST 2021
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Journal of neuroinflammation
Wang M,Feng LR,Li ZL,Ma KG,Chang KW,Chen XL,Yang PB,Ji SF,Ma YB,Han H,Ruganzua JB,Yang WN,Qian YH
Mon Jun 28 00:00:00 EDT 2021
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Environmental science and pollution research international
Jiang L,Qiu T,Yao X,Chen H,Yao K,Sun X,Yang G,Jiang L,Zhang C,Wang N,Zhang H,Liu X
Wed Dec 01 00:00:00 EST 2021
Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult.
Frontiers in immunology
Li J,Sun Z,Luo G,Wang S,Cui H,Yao Z,Xiong H,He Y,Qian Y,Fan C
Mon Sep 27 00:00:00 EDT 2021
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Nature communications
Li WJ,He YH,Yang JJ,Hu GS,Lin YA,Ran T,Peng BL,Xie BL,Huang MF,Gao X,Huang HH,Zhu HH,Ye F,Liu W
Mon Mar 29 00:00:00 EDT 2021
Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD.
International journal of chronic obstructive pulmonary disease
Zhang Z,Fu C,Liu J,Sai X,Qin C,Di T,Yang Y,Wu Y,Bian T
Tue Mar 22 00:00:00 EDT 2022
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Journal of animal science and biotechnology
Chen Y,Zhang H,Chen Y,Jia P,Ji S,Zhang Y,Wang T
Thu Jun 10 00:00:00 EDT 2021
CTR9-mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells.
Journal of clinical laboratory analysis
Xu Y,Chen J,He G,Zhang Y
Wed Sep 01 00:00:00 EDT 2021
Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Biochemical and biophysical research communications
Yang M,Li X,Li H,Zhang X,Liu X,Song Y
Mon Jul 05 00:00:00 EDT 2021
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
Toxicology and applied pharmacology
Wang X,Gong Q,Song C,Fang J,Yang Y,Liang X,Huang X,Liu J
Sat May 01 00:00:00 EDT 2021
Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.
American journal of translational research
Pan Y,Chen Y,Wu C,Ai J,Wang Y,Jia J,Liu L
Sun May 23 00:00:00 EDT 2021
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness.
Journal of translational medicine
Zhang JY,Zhu WW,Wang MY,Zhai RD,Wang Q,Shen WL,Liu LK
Mon Dec 20 00:00:00 EST 2021
circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046.
Frontiers in physiology
Zhang Y,Zhang H,Yuan G,Yang G
Tue Mar 01 00:00:00 EST 2022
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Cell research
Liu M,Zhang W,Li M,Feng J,Kuang W,Chen X,Yang F,Sun Q,Xu Z,Hua J,Yang C,Liu W,Shu Q,Yang Y,Zhou T,Xie S
Mon Nov 01 00:00:00 EDT 2021
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Acta biochimica et biophysica Sinica
Pang B,Zhang J,Zhang X,Yuan J,Shi Y,Qiao L
Tue Mar 02 00:00:00 EST 2021
Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway.
Science China. Life sciences
Feng Y,Cao X,Zhao B,Song C,Pang B,Hu L,Zhang C,Wang J,He J,Wang S
Mon Nov 01 00:00:00 EDT 2021
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
International journal of molecular medicine
Dai W,Wang M,Wang P,Wen J,Wang J,Cha S,Xiao X,He Y,Shu R,Bai D
Mon Feb 01 00:00:00 EST 2021
Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT/mTOR signaling pathway in mice.
Journal of ethnopharmacology
Peng KY,Gu JF,Su SL,Zhu Y,Guo JM,Qian DW,Duan JA
Sun Jan 10 00:00:00 EST 2021
Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells.
Science advances
Sun Y,Lin X,Liu B,Zhang Y,Li W,Zhang S,He F,Tian H,Zhu X,Liu X,Wu J,Cai J,Li M
Fri Dec 24 00:00:00 EST 2021
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.
Journal of ethnopharmacology
Yao H,Zhao J,Zhu L,Xie Y,Zhao N,Yao R,Sun H,Han G
Mon Nov 15 00:00:00 EST 2021
GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer.
International journal of biological sciences
Wang H,Zhang H,Sun Z,Chen W,Miao C
Fri Mar 25 00:00:00 EDT 2022
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
Genome medicine
Guo Y,Wang J,Benedict B,Yang C,van Gemert F,Ma X,Gao D,Wang H,Zhang S,Lieftink C,Beijersbergen RL,Te Riele H,Qiao X,Gao Q,Sun C,Qin W,Bernards R,Wang C
Mon Oct 18 00:00:00 EDT 2021
Yeast Shells Encapsulating Adjuvant AS04 as an Antigen Delivery System for a Novel Vaccine against Toxoplasma Gondii.
ACS applied materials & interfaces
Zhu L,Lei Z,Xia X,Zhang Y,Chen Y,Wang B,Li J,Li G,Yang G,Cao G,Yin Z
Wed Sep 01 00:00:00 EDT 2021
Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma.
International journal of general medicine
Ren X,Wang X,Peng B,Liang Q,Cai Y,Gao K,Hu Y,Xu Z,Yan Y
Thu Apr 28 00:00:00 EDT 2022
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Journal of orthopaedic surgery and research
Liu H,Rui Y,Liu J,Gao F,Jin Y
Wed Nov 03 00:00:00 EDT 2021
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Oxidative medicine and cellular longevity
Peng W,Wan L,Luo Z,Xie Y,Liu Y,Huang T,Lu H,Hu J
Mon Jan 31 00:00:00 EST 2022
Reversine suppresses osteosarcoma cell growth through targeting BMP-Smad1/5/8-mediated angiogenesis.
Microvascular research
Hu L,Li K,Lin L,Qian F,Li P,Zhu L,Cai H,You L,Song J,Kok SHL,Lee KKH,Yang X,Cheng X
Sat May 01 00:00:00 EDT 2021
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Stem cell research & therapy
Zhao Y,Yang X,Li S,Zhang B,Li S,Wang X,Wang Y,Jia C,Chang Y,Wei W
Sat Oct 09 00:00:00 EDT 2021
CDK5 Knockdown inhibits proliferation and induces apoptosis and Cell Cycle Arrest in Human Glioblastoma.
Journal of Cancer
Zhou Y,Wang X,Lv P,Yu H,Jiang X
Tue Jun 08 00:00:00 EDT 2021
HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.
IUBMB life
Jing Y,Gao B,Han Z,Xin S
Wed Sep 01 00:00:00 EDT 2021
The intervention of intestinal Wnt/β-catenin pathway alters inflammation and disease severity of CIA.
Immunologic research
Tan W,Qiu Y,Chen N,Gao J,Liang J,Liu Y,Zhao D
Sun Aug 01 00:00:00 EDT 2021
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma.
Experimental hematology
Yuan J,Zhang Q,Wu S,Yan S,Zhao R,Sun Y,Tian X,Zhou K
Mon Nov 01 00:00:00 EDT 2021
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
Frontiers in oncology
Tian X,Wu L,Jiang M,Zhang Z,Wu R,Miao J,Liu C,Gao S
Sat Jul 16 00:00:00 EDT 2022
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells.
Experimental & molecular medicine
Tran QH,Hoang DH,Song M,Choe W,Kang I,Kim SS,Ha J
Wed Sep 01 00:00:00 EDT 2021
Golgi phosphoprotein 3 promotes the proliferation of gallbladder carcinoma cells via regulation of the NLRP3 inflammasome.
Oncology reports
Zhu Z,Zhu Q,Cai D,Chen L,Xie W,Bai Y,Luo K
Tue Jun 01 00:00:00 EDT 2021
Nonsegmented Negative-Sense RNA Viruses Utilize N6-Methyladenosine (m6A) as a Common Strategy To Evade Host Innate Immunity.
Journal of virology
Lu M,Xue M,Wang HT,Kairis EL,Ahmad S,Wei J,Zhang Z,Liu Q,Zhang Y,Gao Y,Garcin D,Peeples ME,Sharma A,Hur S,He C,Li J
Mon Apr 12 00:00:00 EDT 2021
Identification of a mesenchymal-related signature associated with clinical prognosis in glioma.
Aging
Zhang Z,Chen J,Huo X,Zong G,Huang K,Cheng M,Sun L,Yue X,Bian E,Zhao B
Mon Apr 19 00:00:00 EDT 2021
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline.
Life sciences
Lu P,Yan HJ,Yang C,Feng WC,Hu F,Wu YY,Sun WW,Gao MM,Long YS
Sat May 01 00:00:00 EDT 2021
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
Drug design, development and therapy
Huang JM,Wang CZ,Lu SY,Wang Z,Yan ZQ
Wed Mar 02 00:00:00 EST 2022
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway.
Translational oncology
Liu N,Yan L,Shan F,Wang X,Qu N,Handley MK,Ma M
Thu Apr 01 00:00:00 EDT 2021
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Science advances
Liu C,Ma L,Wang Y,Zhao J,Chen P,Chen X,Wang Y,Hu Y,Liu Y,Jia X,Yang Z,Yin X,Wu J,Wu S,Zheng H,Ma X,Sun X,He Y,Lin L,Fu Y,Liao K,Zhou X,Jiang S,Fu G,Tang J,Han W,Chen XL,Fan W,Hong Y,Han J,Huang X,Li BA,Xiao N,Xiao C,Fu G,Liu WH
Fri Oct 08 00:00:00 EDT 2021
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Food science & nutrition
Chen Y,Liang J,Liang X,Chen J,Wang Y,Cao J,Sun C,Ye J,Chen Q
Thu Apr 01 00:00:00 EDT 2021
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling.
Oncogene
Wang Z,Shi Y,Ying C,Jiang Y,Hu J
Mon Feb 01 00:00:00 EST 2021
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Experimental cell research
Yang D,Ma Y,Zhao P,Ma J,He C
Mon Nov 15 00:00:00 EST 2021
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer.
Bioengineered
Zeng RJ,Xie WJ,Zheng CW,Chen WX,Wang SM,Li Z,Cheng CB,Zou HY,Xu LY,Li EM
Wed Dec 01 00:00:00 EST 2021
PPy@Fe3O4 Nanoparticles Inhibit Tumor Growth and Metastasis Through Chemodynamic and Photothermal Therapy in Non-small Cell Lung Cancer.
Frontiers in chemistry
Fang D,Jin H,Huang X,Shi Y,Liu Z,Ben S
Fri Nov 26 00:00:00 EST 2021
Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes.
Medical science monitor : international medical journal of experimental and clinical research
Sun D,Yang L,Zheng W,Cao H,Wu L,Song H
Fri Jun 11 00:00:00 EDT 2021
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.
Molecular medicine reports
Liu M,Zheng B,Liu P,Zhang J,Chu X,Dong C,Shi J,Liang Y,Chu L,Liu Y,Han X
Tue Jun 01 00:00:00 EDT 2021
Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro.
Viruses
Hulsebosch BM,Mounce BC
Tue Feb 16 00:00:00 EST 2021
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Frontiers in pharmacology
Zhang Y,Fu Y,Jiang T,Liu B,Sun H,Zhang Y,Fan B,Li X,Qin X,Zheng Q
Wed Dec 15 00:00:00 EST 2021
METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.
Molecular medicine (Cambridge, Mass.)
Li M,Deng L,Xu G
Thu Sep 09 00:00:00 EDT 2021
Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses.
Frontiers in neuroscience
Wang C,Chen H,Jiang HH,Mao BB,Yu H
Tue Dec 28 00:00:00 EST 2021
The Ginsenoside Rg1 Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice.
Life (Basel, Switzerland)
Chou CK,Huang YS,Lin PY,Imai K,Chen SM,Lee JA
Mon Sep 27 00:00:00 EDT 2021
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
Clinical science (London, England : 1979)
Jiang H,Ding D,He Y,Li X,Xu Y,Liu X
Fri Nov 12 00:00:00 EST 2021
Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint.
The Journal of biological chemistry
Yu B,Liu Y,Luo H,Fu J,Li Y,Shao C
Mon Aug 02 00:00:00 EDT 2021
Sitagliptin activates the p62-Keap1-Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury.
Cell death & disease
Kong L,Deng J,Zhou X,Cai B,Zhang B,Chen X,Chen Z,Wang W
Mon Oct 11 00:00:00 EDT 2021
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
eLife
Le Vasseur M,Friedman J,Jost M,Xu J,Yamada J,Kampmann M,Horlbeck MA,Salemi MR,Phinney BS,Weissman JS,Nunnari J
Wed May 26 00:00:00 EDT 2021
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Frontiers in immunology
Ma M,Li G,Qi M,Jiang W,Zhou R
Fri Dec 17 00:00:00 EST 2021
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
Scientific reports
Ryu J,Stone P,Lee S,Payne B,Gorse K,Lafrenaye A
Wed Apr 21 00:00:00 EDT 2021
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Frontiers in immunology
Yang M,Huang Q,Li C,Jiang Z,Sun J,Wang Z,Liang R,Li D,Li B,Zhao H
Wed Oct 06 00:00:00 EDT 2021
IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3.
Frontiers in cellular neuroscience
Liu H,Yang X,Yang J,Yuan Y,Wang Y,Zhang R,Xiong H,Xu Y
Sat Jul 10 00:00:00 EDT 2021
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.
Nature communications
Liu W,Xie L,He YH,Wu ZY,Liu LX,Bai XF,Deng DX,Xu XE,Liao LD,Lin W,Heng JH,Xu X,Peng L,Huang QF,Li CY,Zhang ZD,Wang W,Zhang GR,Gao X,Wang SH,Li CQ,Xu LY,Liu W,Li EM
Mon Aug 16 00:00:00 EDT 2021
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Theranostics
Liao Z,Chen Y,Duan C,Zhu K,Huang R,Zhao H,Hintze M,Pu Q,Yuan Z,Lv L,Chen H,Lai B,Feng S,Qi X,Cai D
Thu Aug 05 00:00:00 EDT 2021
FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
NPJ aging and mechanisms of disease
Criado-Marrero M,Gebru NT,Gould LA,Blazier DM,Vidal-Aguiar Y,Smith TM,Abdelmaboud SS,Shelton LB,Wang X,Dahrendorff J,Beaulieu-Abdelahad D,Dickey CA,Blair LJ
Mon May 03 00:00:00 EDT 2021
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Cell reports
Watson AW,Grant AD,Parker SS,Hill S,Whalen MB,Chakrabarti J,Harman MW,Roman MR,Forte BL,Gowan CC,Castro-Portuguez R,Stolze LK,Franck C,Cusanovich DA,Zavros Y,Padi M,Romanoski CE,Mouneimne G
Tue Jun 29 00:00:00 EDT 2021
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Cell death discovery
Ge W,Wang Y,Zheng S,Zhao D,Wang X,Zhang X,Hu Y
Mon Jul 26 00:00:00 EDT 2021
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
Experimental cell research
Hu Y,Cheng Y,Jiang X,Zhang Y,Wang H,Ren H,Xu Y,Jiang J,Wang Q,Su H,Zhang B,Qiu X
Mon Mar 15 00:00:00 EDT 2021
Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production.
Frontiers in cardiovascular medicine
Chang X,Zhao Y,Qin S,Wang H,Wang B,Zhai L,Liu B,Gu HM,Zhang DW
Fri May 26 00:00:00 EDT 2023
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Frontiers in immunology
Li W,Qiao J,You Q,Zong S,Peng Q,Liu Y,Hu S,Liu W,Li S,Shu X,Sun B
Tue Dec 14 00:00:00 EST 2021
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
International journal of biological sciences
Lu L,Li X,Zhong Z,Zhou W,Zhou D,Zhu M,Miao C
Mon Dec 20 00:00:00 EST 2021
Environmental Pollutant Benzo[a]pyrene Upregulated Long Non-coding RNA HZ07 Inhibits Trophoblast Cell Migration by Inactivating PI3K/AKT/MMP2 Signaling Pathway in Recurrent Pregnancy Loss.
Reproductive sciences (Thousand Oaks, Calif.)
Ye Y,Jiang S,Du T,Ding M,Hou M,Mi C,Liang T,Zhong H,Xie J,Xu W,Zhang H,Zhao X
Mon Nov 01 00:00:00 EDT 2021
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen X,Tang H,Liang Y,Wu P,Xie L,Ding Y,Yang P,Long B,Lin J
Wed Dec 01 00:00:00 EST 2021
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Frontiers in cell and developmental biology
Zhu T,Liu B,Wu D,Xu G,Fan Y
Tue Dec 07 00:00:00 EST 2021
Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
Bioengineered
Dong L,Huang J,Zu P,Liu J,Gao X,Du J,Li Y
Wed Dec 01 00:00:00 EST 2021
Small extracellular vesicle-mediated Hsp70 intercellular delivery enhances breast cancer adriamycin resistance.
Free radical biology & medicine
Hu W,Xu Z,Zhu S,Sun W,Wang X,Tan C,Zhang Y,Zhang G,Xu Y,Tang J
Sat Feb 20 00:00:00 EST 2021
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma.
OncoTargets and therapy
Peng X,Sun J,Long Y,Xiao D,Zhou J,Tao Y,Liu S
Thu Apr 21 00:00:00 EDT 2022
Characterization of Pathogenesis and Inflammatory Responses to Experimental Parechovirus Encephalitis.
Frontiers in immunology
Jan MW,Su HL,Chang TH,Tsai KJ
Fri Feb 25 00:00:00 EST 2022
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.
Cell chemical biology
Luo M,Spradlin JN,Boike L,Tong B,Brittain SM,McKenna JM,Tallarico JA,Schirle M,Maimone TJ,Nomura DK
Thu Apr 15 00:00:00 EDT 2021
Protective Effect of Retrograde Reperfusion Against Hepatic Autophagy Impairment in Rat Liver Transplantation.
Transplantation proceedings
Cheng Y,Lan H,Chen Y,Jiang Y,Chen Y
Thu May 06 00:00:00 EDT 2021
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
Biochemical pharmacology
Han S,Wang Z,Liu J,Wang HD,Yuan Q
Tue Jun 01 00:00:00 EDT 2021
ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.
Journal of Cancer
Yang HL,Xu C,Yang YK,Tang WQ,Hong M,Pan L,Chen HY
Sat Feb 19 00:00:00 EST 2022
NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis.
Cancer biology & therapy
Zheng RH,Zhang YB,Qiu FN,Liu ZH,Han Y,Huang R,Zhao Y,Yao P,Qiu Y,Ren J
Mon Feb 01 00:00:00 EST 2021
An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1.
Frontiers in microbiology
Fu M,Liang S,Wu J,Hua Y,Chen H,Zhang Z,Liu J,Li X,Zhang B,Zhao W,Wan C
Tue Jun 15 00:00:00 EDT 2021
Mir-139-5p inhibits glioma cell proliferation and progression by targeting GABRA1.
Journal of translational medicine
Wang L,Liu Y,Yu Z,Gong J,Deng Z,Ren N,Zhong Z,Cai H,Tang Z,Cheng H,Chen S,He Z
Mon May 17 00:00:00 EDT 2021
MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.
Frontiers in cell and developmental biology
Yang F,Kou J,Liu Z,Li W,Du W
Mon Jun 28 00:00:00 EDT 2021
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Journal of cell science
Li W,Liu C,Huang Z,Shi L,Zhong C,Zhou W,Meng P,Li Z,Wang S,Luo F,Yan J,Wu T
Thu Apr 15 00:00:00 EDT 2021
Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions.
The Journal of international medical research
Yu M,Sun L,Ba P,Li L,Chen J,Sun Q
Sun Aug 01 00:00:00 EDT 2021
Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression.
Cancers
Chen WT,Yang HB,Ke TW,Liao WL,Hung SY
Wed Aug 18 00:00:00 EDT 2021
Upregulated Nmnat2 causes neuronal death and increases seizure susceptibility in temporal lobe epilepsy.
Brain research bulletin
Wu H,Meng Q,Zhang Y,Li H,Liu Y,Dong S,Liu B,Zhang H
Mon Feb 01 00:00:00 EST 2021
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
International journal of cardiology
Cui J,Xu G,Bian F
Wed Sep 01 00:00:00 EDT 2021
Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.
Journal of medicinal chemistry
Ojha R,Chen IC,Hsieh CM,Nepali K,Lai RW,Hsu KC,Lin TE,Pan SL,Chen MC,Liou JP
Thu Dec 23 00:00:00 EST 2021
Protocols for Characterization of Cdk5 Kinase Activity.
Current protocols
Terse A,Amin N,Hall B,Bhaskar M,B K B,Utreras E,Pareek TK,Pant H,Kulkarni AB
Fri Oct 01 00:00:00 EDT 2021
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca2+ Signaling Pathway.
Frontiers in pharmacology
Liu L,Zhang Q,Xiao S,Sun Z,Ding S,Chen Y,Wang L,Yin X,Liao F,Jiang LH,Xue M,You Y
Tue Apr 13 00:00:00 EDT 2021
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis.
Mediators of inflammation
Guo X,Xu Y,Tan HL,Wang XJ,Xiao L
Mon Feb 07 00:00:00 EST 2022
Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.
Molecular medicine reports
Zhou N,Yan B,Ma J,Jiang H,Li L,Tang H,Ji F,Yao Z
Wed Sep 01 00:00:00 EDT 2021
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Frontiers in medicine
Yao M,Zhang J,Li Z,Bai X,Ma J,Li Y
Wed Mar 10 00:00:00 EST 2021
Correction: Injectable postoperative enzyme-responsive hydrogels for reversing temozolomide resistance and reducing local recurrence after glioma operation.
Biomaterials science
Zhao Z,Shen J,Zhang L,Wang L,Xu H,Han Y,Jia J,Lu Y,Yu R,Liu H
Tue Feb 23 00:00:00 EST 2021
Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia.
Journal of inflammation research
Lu F,Wang R,Xia L,Nie T,Gao F,Yang S,Huang L,Shao K,Liu J,Yang Q
Sun Apr 24 00:00:00 EDT 2022
Protection against Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Neferine, A Natural Product from Nelumbo nucifera Gaertn.
Cell journal
Min X,Guo Y,Zhou Y,Chen X
Fri Jan 01 00:00:00 EST 2021
TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia.
Cell death & disease
Zhang Y,Hou B,Liang P,Lu X,Wu Y,Zhang X,Fan Y,Liu Y,Chen T,Liu W,Peng B,Yin J,Han S,He X
Tue Dec 14 00:00:00 EST 2021
ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Frontiers in cell and developmental biology
Yu S,Zhang R,Shen Q,Zhu Z,Zhang J,Wu X,Zhao W,Li N,Yang F,Wei H,Hua J
Fri Oct 08 00:00:00 EDT 2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Brain : a journal of neurology
Shireman JM,Atashi F,Lee G,Ali ES,Saathoff MR,Park CH,Savchuk S,Baisiwala S,Miska J,Lesniak MS,James CD,Stupp R,Kumthekar P,Horbinski CM,Ben-Sahra I,Ahmed AU
Fri May 07 00:00:00 EDT 2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
International immunopharmacology
Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q
Mon Nov 01 00:00:00 EDT 2021
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Frontiers in physiology
Xu Q,Li S,Tang W,Yan J,Wei X,Zhou M,Diao H
Tue Oct 26 00:00:00 EDT 2021
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Journal of neuroinflammation
Wang X,Li X,Zuo X,Liang Z,Ding T,Li K,Ma Y,Li P,Zhu Z,Ju C,Zhang Z,Song Z,Quan H,Zhang J,Hu X,Wang Z
Fri Nov 05 00:00:00 EDT 2021
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Frontiers in physiology
Wang F,Sun C,Lv X,Sun M,Si C,Zhen Y,Guo J,Sun W,Ye Z,Wen J,Liu P
Sat Dec 04 00:00:00 EST 2021
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B.
American journal of cancer research
Li J,Yang J,Hua L,Wang R,Li H,Zhang C,Zhang H,Li S,Zhu L,Su H
Tue Feb 02 00:00:00 EST 2021
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling.
Experimental biology and medicine (Maywood, N.J.)
Yu X,Xia J,Cao Y,Tang L,Tang X,Li Z
Fri Jan 01 00:00:00 EST 2021
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.
FEBS open bio
Cheng A,Guo X,Dai X,Wang Z
Tue Jun 01 00:00:00 EDT 2021
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
Laryngoscope investigative otolaryngology
Liu HT,Xia T,You YW,Zhang QC,Ni HS,Liu YF,Liu YR,Xu YQ,You B,Zhang ZX
Fri Oct 01 00:00:00 EDT 2021
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Aging
Lu L,Lu T,Shen J,Lv X,Wei W,Wang H,Xue X
Fri Jun 04 00:00:00 EDT 2021
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Biochimie
Noori AR,Tashakor A,Nikkhah M,Eriksson LA,Hosseinkhani S,Fearnhead HO
Fri Jan 01 00:00:00 EST 2021
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway.
Food & function
Luo M,Zheng LW,Wang YS,Huang JC,Yang ZQ,Yue ZP,Guo B
Mon Sep 20 00:00:00 EDT 2021
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
Biochemical pharmacology
Xia S,Wang Z,Chen L,Zhou Y,Li Y,Wang S,Chen A,Xu X,Shao J,Zhang Z,Tan S,Zhang F,Zheng S
Fri Oct 01 00:00:00 EDT 2021
Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin.
Bioengineered
Wang Y,Cheng Z,Xu J,Lai M,Liu L,Zuo M,Dang L
Wed Dec 01 00:00:00 EST 2021
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
PloS one
Anchoori RK,George L,Tseng SH,Lam B,Polkampally S,Amiano AD,Foran P,Tsingine H,Samanapally H,Carrizo Velasquez F,Das S,Xing D,Bin Salam A,Karanam B,Hung CF,Roden RBS
Thu Nov 18 00:00:00 EST 2021
Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal.
NPJ science of food
Zheng Y,Martin-Morales A,Wang J,Fujishima M,Okumura E,Sato K
Fri Jul 23 00:00:00 EDT 2021
Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.
Journal of ethnopharmacology
Chen B,Wei J,Zhu R,Zhang H,Xia B,Liu Y,Dai X,Ye Z,Tian Y,Li R,Zhao D,Mo F,Orekhov AN,Gao S,Br¿mme D,Wang L,Zhang D
Thu Oct 28 00:00:00 EDT 2021
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.
Free radical research
Oshimo M,Nakashima F,Kai K,Matsui H,Shibata T,Akagawa M
Tue Jun 01 00:00:00 EDT 2021
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
Bioengineered
Liu H,Chi Z,Jin H,Yang W
Wed Dec 01 00:00:00 EST 2021
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro.
BMC biotechnology
Li J,Yu J,Xue W,Huang H,Yan L,Sang F,An S,Zhang J,Wang M,Zhang J,Li H,Cui X,He J,Hu Y
Mon Jun 14 00:00:00 EDT 2021
A subcellular map of the human kinome.
eLife
Zhang H,Cao X,Tang M,Zhong G,Si Y,Li H,Zhu F,Liao Q,Li L,Zhao J,Feng J,Li S,Wang C,Kaulich M,Wang F,Chen L,Li L,Xia Z,Liang T,Lu H,Feng XH,Zhao B
Fri May 14 00:00:00 EDT 2021
TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.
Frontiers in cell and developmental biology
Zhang MY,Zhu L,Zheng X,Xie TH,Wang W,Zou J,Li Y,Li HY,Cai J,Gu S,Yao Y,Wei TT
Tue Feb 01 00:00:00 EST 2022
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
Oxidative medicine and cellular longevity
Ding X,Nie Z,She Z,Bai X,Yang Q,Wang F,Wang F,Geng X
Wed May 19 00:00:00 EDT 2021
CTHRC1 Knockdown Promotes Inflammatory Responses Partially by p38 MAPK Activation in Human Periodontal Ligament Cells.
Inflammation
Guo Y,Jiang C,Yao S,Ma L,Zhang H,Wang X,Xu S,Cao Z
Fri Oct 01 00:00:00 EDT 2021
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Journal of neuroimmunology
Xu X,Xu H,Ren F,Huang L,Xu J,Li F
Tue Jun 15 00:00:00 EDT 2021
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
International journal of endocrinology
Hu X,Li M,Zhang C,Pang S
Wed Apr 20 00:00:00 EDT 2022
Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
Acta pharmaceutica Sinica. B
Zhang S,Zhang J,An Y,Zeng X,Qin Z,Zhao Y,Xu H,Liu B
Sat May 01 00:00:00 EDT 2021
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Experimental eye research
Wang Y,Wu Z,Huang Y,Zhang Y
Fri Oct 01 00:00:00 EDT 2021
Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Metabolism: clinical and experimental
Li Y,Li J,Zhao C,Yang L,Qi X,Wang X,Zhou Q,Shi W
Fri Jan 01 00:00:00 EST 2021
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Carbohydrate polymers
Xu R,Zhang K,Liang J,Gao F,Li J,Guan F
Tue Jun 01 00:00:00 EDT 2021
Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells.
International journal of molecular sciences
Shi T,Iwama H,Fujita K,Kobara H,Nishiyama N,Fujihara S,Goda Y,Yoneyama H,Morishita A,Tani J,Yamada M,Nakahara M,Takuma K,Masaki T
Thu Dec 02 00:00:00 EST 2021
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Cell proliferation
Xu Y,Sang W,Zhong Y,Xue S,Yang M,Wang C,Lu H,Huan R,Mao X,Zhu L,He C,Ma J
Wed Dec 01 00:00:00 EST 2021
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
European journal of medicinal chemistry
Chen W,Chen X,Li D,Wang X,Long G,Jiang Z,You Q,Guo X
Fri Nov 05 00:00:00 EDT 2021
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma.
Molecular medicine reports
Zhan K,Bai Y,Liao S,Chen H,Kuang L,Luo Q,Lv L,Qiu L,Mei Z
Wed Sep 01 00:00:00 EDT 2021
DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
PLoS pathogens
Pan P,Li G,Shen M,Yu Z,Ge W,Lao Z,Fan Y,Chen K,Ding Z,Wang W,Wan P,Shereen MA,Luo Z,Chen X,Zhang Q,Lin L,Wu J
Thu Jul 01 00:00:00 EDT 2021
Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation.
European journal of pharmacology
Sun Z,Li J,Luo G,Liu W,He Y,Wang F,Qian Y,Fan C
Fri Oct 15 00:00:00 EDT 2021
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chinese journal of natural medicines
Chen YD,Cai FY,Mao YZ,Yang YS,Xu K,Liu XF,Fan WW,Chen W,Jiang FQ,Zhang H
Mon Nov 01 00:00:00 EDT 2021
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Neurochemical research
Qi Z,Zhang Y,Yao K,Zhang M,Xu Y,Zhang J,Bai X,Zu H
Thu Jul 01 00:00:00 EDT 2021
Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
Metabolism: clinical and experimental
Wu M,Yang Z,Zhang C,Shi Y,Han W,Song S,Mu L,Du C,Shi Y
Sat May 01 00:00:00 EDT 2021
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression.
Acta pharmacologica Sinica
Xue GL,Li DS,Wang ZY,Liu Y,Yang JM,Li CZ,Li XD,Ma JD,Zhang MM,Lu YJ,Li Y,Yang BF,Pan ZW
Mon Nov 01 00:00:00 EDT 2021
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.
Molecular cell
Pan Q,Zhong S,Wang H,Wang X,Li N,Li Y,Zhang G,Yuan H,Lian Y,Chen Q,Han Y,Guo J,Liu Q,Qiu T,Jiang J,Li Q,Tan M,Yin H,Peng J,Xiao Y,Qin J
Thu Jul 01 00:00:00 EDT 2021
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Journal of agricultural and food chemistry
Luo N,Yang C,Zhu Y,Chen Q,Zhang B
Wed Jan 20 00:00:00 EST 2021
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Journal of Cancer
Yu J,Wang W,Liu B,Gu J,Chen S,Cui Y,Sun G
Tue Jun 08 00:00:00 EDT 2021
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.
Food & function
Liu A,Lin L,Xu W,Gong Z,Liu Z,Xiao W
Mon Jul 05 00:00:00 EDT 2021
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Annals of translational medicine
Guan Y,Li Y,Yang QB,Yu J,Qiao H
Thu Apr 01 00:00:00 EDT 2021
Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
BMC complementary medicine and therapies
Zhang DF,Yang ZC,Chen JQ,Jin XX,Qiu YD,Chen XJ,Shi HY,Liu ZG,Wang MS,Liang G,Zheng XH
Tue Jul 06 00:00:00 EDT 2021
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway.
Frontiers in genetics
Li Y,Wang X,Xu H,Li G,Huo Z,Du L,Zhang K,Shen L,Li H,Xu B
Tue Jun 29 00:00:00 EDT 2021
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Tang C,Luo Y,Li S,Huang B,Xu S,Li L
Fri Jan 01 00:00:00 EST 2021
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
Journal of translational medicine
Li S,Ma J,Zheng A,Song X,Chen S,Jin F
Fri Aug 06 00:00:00 EDT 2021
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Frontiers in chemistry
Shang Y,Wang Q,Li J,Liu H,Zhao Q,Huang X,Dong H,Chen W,Gui R,Nie X
Sat Apr 03 00:00:00 EDT 2021
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lin Z,Miao J,Zhang T,He M,Zhou X,Zhang H,Gao Y,Bai L
Mon Mar 01 00:00:00 EST 2021
Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR‑9.
Oncology reports
Sheng W,Xu W,Ding J,Li L,You X,Wu Y,He Q
Mon Nov 01 00:00:00 EDT 2021
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Clinical science (London, England : 1979)
Wu M,Chen W,Miao M,Jin Q,Zhang S,Bai M,Fan J,Zhang Y,Zhang A,Jia Z,Huang S
Fri Jul 30 00:00:00 EDT 2021
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Nature metabolism
Xu Q,Fu Q,Li Z,Liu H,Wang Y,Lin X,He R,Zhang X,Ju Z,Campisi J,Kirkland JL,Sun Y
Wed Dec 01 00:00:00 EST 2021
Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity.
Journal of virology
Liu X,Liu X,Bai J,Gao Y,Song Z,Nauwynck H,Wang X,Yang Y,Jiang P
Wed Aug 25 00:00:00 EDT 2021
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Clinical science (London, England : 1979)
Cheng L,Chen T,Guo M,Liu P,Qiao X,Wei Y,She J,Li B,Xi W,Zhou J,Yuan Z,Wu Y,Liu J
Fri Jul 30 00:00:00 EDT 2021
Perilipin 4 Protein: an Impending Target for Amyotrophic Lateral Sclerosis.
Molecular neurobiology
Zhu L,Hu F,Li C,Zhang C,Hang R,Xu R
Thu Apr 01 00:00:00 EDT 2021
Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.
Frontiers in veterinary science
Lin Z,Lin Z,Zhao Y,Cheng N,Zhang D,Lin J,Zhang H,Lin D
Tue Jan 04 00:00:00 EST 2022
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Drug design, development and therapy
Li H,Sheng J,Wang J,Gao H,Yu J,Ding G,Ding N,He W,Zha J
Mon Nov 29 00:00:00 EST 2021
Interleukin-37 inhibits inflammation activation and disease severity of PM2.5-induced airway hyperresponsiveness.
Ecotoxicology and environmental safety
Wang M,Hou S,Lu X,Li J,Li R,Yan X
Mon Dec 20 00:00:00 EST 2021
Activation of Adenosine A1 Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
Antioxidants (Basel, Switzerland)
Ruan L,Li G,Zhao W,Meng H,Zheng Q,Wang J
Mon Jul 12 00:00:00 EDT 2021
Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells.
Veterinary microbiology
Xie X,Pang M,Liang S,Lin Y,Zhao Y,Qiu D,Liu J,Dong Y,Liu Y
Tue Jun 01 00:00:00 EDT 2021
Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.
Frontiers in bioengineering and biotechnology
Yu Y,Niu J,Zhang X,Wang X,Song H,Liu Y,Jiao X,Chen F
Sat Jan 29 00:00:00 EST 2022
HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.
BMC medical genomics
Wang FJ,Jing YH,Cheng CS,Cao ZQ,Jiao JY,Chen Z
Tue Jul 27 00:00:00 EDT 2021
Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.
Molecular therapy : the journal of the American Society of Gene Therapy
Liu N,Zhang J,Yin M,Liu H,Zhang X,Li J,Yan B,Guo Y,Zhou J,Tao J,Hu S,Chen X,Peng C
Wed Jul 07 00:00:00 EDT 2021
Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models.
Bioscience, biotechnology, and biochemistry
Wang Y,Guo S,Jia Y,Yu X,Mou R,Li X
Wed Mar 24 00:00:00 EDT 2021
Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Frontiers in pharmacology
Yin Z,Geng X,Zhang Z,Wang Y,Gao X
Wed Sep 29 00:00:00 EDT 2021
Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway.
Drug design, development and therapy
Xiu AY,Ding Q,Li Z,Zhang CQ
Thu Jan 20 00:00:00 EST 2022
Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment.
Pharmaceutics
Chen S,Deng C,Zheng W,Li S,Liu Y,Zhang T,Zhang C,Fu Y,Miao H,Ren F,Ma X
Tue Sep 07 00:00:00 EDT 2021
Maternal folic acid supplementation prevents autistic behaviors in a rat model induced by prenatal exposure to valproic acid.
Food & function
Di Y,Li Z,Li J,Cheng Q,Zheng Q,Zhai C,Kang M,Wei C,Lan J,Fan J,Ren W,Tian Y
Fri May 21 00:00:00 EDT 2021
The miR-145-5p/CD36 pathway mediates PCB2-induced apoptosis in MCF-7 cells.
Genes & genomics
Yuan Y,Xue C,Wu Q,Wang M,Liu J,Zhang L,Xing Q,Liang J,Wu H,Chen Z
Mon Feb 01 00:00:00 EST 2021
Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen X,He X,Guo Y,Liu L,Li H,Tan J,Feng W,Guan H,Cao X,Xiao H,Li Y
Sat May 01 00:00:00 EDT 2021
Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress.
Ecotoxicology and environmental safety
Wang Y,Zhao H,Mu M,Guo M,Xing M
Fri Jan 15 00:00:00 EST 2021
Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption.
ACS applied materials & interfaces
Song G,Dong H,Ma D,Wang H,Ren X,Qu Y,Wu H,Zhu J,Song W,Meng Y,Wang L,Liu T,Shen X,Zhao Y,Zhu C
Wed Oct 06 00:00:00 EDT 2021
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells.
Frontiers in immunology
Teo Hansen Selnø A,Schlichtner S,Yasinska IM,Sakhnevych SS,Fiedler W,Wellbrock J,Berger SM,Klenova E,Gibbs BF,Fasler-Kan E,Sumbayev VV
Thu Oct 21 00:00:00 EDT 2021
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Journal of Cancer
Wang T,Zhang W,Huang W,Hua Z,Li S
Fri Oct 22 00:00:00 EDT 2021
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Molecular oncology
Liu M,Fan Y,Li D,Han B,Meng Y,Chen F,Liu T,Song Z,Han Y,Huang L,Chang Y,Cao P,Nakai A,Tan K
Sun Aug 01 00:00:00 EDT 2021
MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.
Journal of cellular and molecular medicine
Lei W,Li J,Li C,Chen L,Huang F,Xiao D,Zhang J,Zhao J,Li G,Qu T,Zhou H,Liao Y,Chen M
Thu Apr 01 00:00:00 EDT 2021
Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.
PLoS pathogens
Xue M,Zhang Y,Wang H,Kairis EL,Lu M,Ahmad S,Attia Z,Harder O,Zhang Z,Wei J,Chen P,Gao Y,Peeples ME,Sharma A,Boyaka P,He C,Hur S,Niewiesk S,Li J
Wed Dec 01 00:00:00 EST 2021
A living cell-based fluorescent reporter for high-throughput screening of anti-tumor drugs.
Journal of pharmaceutical analysis
Tang N,Li L,Xie F,Lu Y,Zuo Z,Shan H,Zhang Q,Zhang L
Wed Dec 01 00:00:00 EST 2021
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation.
Bioengineered
Hui Z,Dong QQ,Shu HP,Tu YC,Liao QQ,Yao LJ
Wed Dec 01 00:00:00 EST 2021
Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
Neurobiology of aging
Salazar AM,Leisgang AM,Ortiz AA,Murtishaw AS,Kinney JW
Fri Jan 01 00:00:00 EST 2021
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice.
Journal of agricultural and food chemistry
Huang WC,Liu JC,Hsia CW,Fong TH,Hsia CH,Tran OT,Velusamy M,Yang CH,Sheu JR
Wed Apr 28 00:00:00 EDT 2021
Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Journal of agricultural and food chemistry
Zhou G,Hu Y,Wang A,Guo M,Du Y,Gong Y,Ding L,Feng Z,Hou X,Xu K,Yu F,Li Z,Ba Y
Wed Nov 17 00:00:00 EST 2021
Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.
Cell biochemistry and biophysics
Gao R,Li Z,Ai D,Ma J,Chen C,Liu X
Tue Jun 01 00:00:00 EDT 2021
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Life sciences
Tan Y,Li M,Wu G,Lou J,Feng M,Xu J,Zhou J,Zhang P,Yang H,Dong L,Li J,Zhang X,Gao F
Sat May 01 00:00:00 EDT 2021
Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.
Frontiers in neuroscience
Wang X,Zhang Z,Zhu Z,Liang Z,Zuo X,Ju C,Song Z,Li X,Hu X,Wang Z
Sat Nov 20 00:00:00 EST 2021
Unexpected Implication of SRP and AGO2 in Parkinson's Disease: Involvement in Alpha-Synuclein Biogenesis.
Cells
Hernandez SM,Tikhonova EB,Baca KR,Zhao F,Zhu X,Karamyshev AL
Mon Oct 18 00:00:00 EDT 2021
Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang R,Xie Y,Li Q,Ye Y,Shi Y,Zhao X,Wu C,Xu Y,Wang R,Zhang Y,Yang X,Han X,Liu S
Wed Sep 01 00:00:00 EDT 2021
Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
Food research international (Ottawa, Ont.)
Han B,Jiang P,Jiang L,Li X,Ye X
Mon Mar 01 00:00:00 EST 2021
Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo.
International immunopharmacology
Ma Y,Luo L,Liu X,Li H,Zeng Z,He X,Zhan Z,Chen Y
Thu Jul 01 00:00:00 EDT 2021
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Han D,Xu Y,Peng WP,Feng F,Wang Z,Gu C,Zhou X
Fri Mar 12 00:00:00 EST 2021
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Journal of oncology
Wang J,Xiao K,Hou F,Tang L,Luo D,Liu G,Wang Z
Thu Jul 15 00:00:00 EDT 2021
miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition.
Cancer cell international
Huang S,Hua X,Kuang M,Zhu J,Mu H,Tian Z,Zheng X,Xie Q
Thu Apr 29 00:00:00 EDT 2021
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Cell death & disease
Gao L,Liu Y,Du X,Ma S,Ge M,Tang H,Han C,Zhao X,Liu Y,Shao Y,Wu Z,Zhang L,Meng F,Xiao-Feng Qin F
Mon Jul 05 00:00:00 EDT 2021
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway.
Frontiers in cell and developmental biology
Fang S,Luo Y,Zhang Y,Wang H,Liu Q,Li X,Yu T
Tue Jul 20 00:00:00 EDT 2021
p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53.
Cells
Zhang Q,Zhang Y,Zhang J,Zhang D,Li M,Yan H,Zhang H,Song L,Wang J,Hou Z,Yang Y,Zou X
Mon Dec 20 00:00:00 EST 2021
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
Mediators of inflammation
Ni S,Yang B,Xia L,Zhang H
Wed Dec 22 00:00:00 EST 2021
SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia/reperfusion injury.
Free radical research
Wang Y,Wu CJ,Du Y,Liu YQ,Cai JR,Wu XQ,Hu SQ
Wed Dec 01 00:00:00 EST 2021
Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells.
Experimental and therapeutic medicine
Wang D,Bi L,Ran J,Zhang L,Xiao N,Li X
Mon Nov 01 00:00:00 EDT 2021
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Wang Y,Karki R,Zheng M,Kancharana B,Lee S,Kesavardhana S,Hansen BS,Pruett-Miller SM,Kanneganti TD
Mon Nov 15 00:00:00 EST 2021
SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation.
Frontiers in immunology
Liu JW,Chu M,Jiao YJ,Zhou CM,Qi R,Yu XJ
Mon Jun 28 00:00:00 EDT 2021
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Cancer communications (London, England)
Wei H,Ma W,Lu X,Liu H,Lin K,Wang Y,Ye Z,Sun L,Huang Z,Pan T,Zhou Z,Cheng EY,Zhang H,Gao P,Zhong X
Wed Sep 01 00:00:00 EDT 2021
Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
Cancers
Tramonti A,Cuyàs E,Encinar JA,Pietzke M,Paone A,Verdura S,Arbusà A,Martin-Castillo B,Giardina G,Joven J,Vazquez A,Contestabile R,Cutruzzolà F,Menendez JA
Mon Aug 09 00:00:00 EDT 2021
SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
PLoS genetics
Tian Y,Kang Q,Shi X,Wang Y,Zhang N,Ye H,Xu Q,Xu T,Zhang R
Tue Jun 01 00:00:00 EDT 2021
β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota.
Frontiers in nutrition
Yu Y,Cao Y,Huang W,Liu Y,Lu Y,Zhao J
Tue Jun 29 00:00:00 EDT 2021
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway.
European journal of pharmacology
Chen Y,Wang J,Li J,Zhu J,Wang R,Xi Q,Wu H,Shi T,Chen W
Mon Nov 15 00:00:00 EST 2021
An enzyme-responsive Gp1a-hydrogel for skin wound healing.
Journal of biomaterials applications
Zhao C,Dong Y,Liu J,Cai H,Li Z,Sun X,Yin W,Ma J,Liu H,Li S
Fri Oct 01 00:00:00 EDT 2021
The piRNA pathway is essential for generating functional oocytes in golden hamsters.
Nature cell biology
Zhang H,Zhang F,Chen Q,Li M,Lv X,Xiao Y,Zhang Z,Hou L,Lai Y,Zhang Y,Zhang A,Gao S,Fu H,Xiao W,Zhou J,Diao F,Shi A,Su YQ,Zeng W,Wu L,Li J
Wed Sep 01 00:00:00 EDT 2021
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Aging
Lv S,Yuan P,Lu C,Dong J,Li M,Qu F,Zhu Y,Zhang J
Thu Feb 11 00:00:00 EST 2021
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8).
Microbiology spectrum
Zhao N,Ming S,Sun L,Wang B,Li H,Zhang X,Zhao X
Fri Sep 03 00:00:00 EDT 2021
Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs.
ACS applied materials & interfaces
Yang L,He X,Jing G,Wang H,Niu J,Qian Y,Wang S
Wed Oct 20 00:00:00 EDT 2021
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats.
Neurochemical research
Ren Y,Jiang J,Jiang W,Zhou X,Lu W,Wang J,Luo Y
Wed Sep 01 00:00:00 EDT 2021
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Journal of cellular physiology
Qi M,Tan B,Wang J,Liao S,Li J,Cui Z,Shao Y,Ji P,Yin Y
Thu Apr 01 00:00:00 EDT 2021
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Nature communications
Yoo JS,Sasaki M,Cho SX,Kasuga Y,Zhu B,Ouda R,Orba Y,de Figueiredo P,Sawa H,Kobayashi KS
Mon Nov 15 00:00:00 EST 2021
mPEG2k-PCL Polymeric Micelles Influence Pharmacokinetics and Hypoglycemic Efficacy of Metformin through Inhibition of Organic Cation Transporters in Rats.
Molecular pharmaceutics
Zhang Y,Sun M,Jian S,Huang J,Xiao C,Zhang X,Hu R,Si L
Mon Jul 05 00:00:00 EDT 2021
Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction.
International immunopharmacology
Liu X,Jin J,Liu Y,Shen Z,Zhao R,Ou L,Xing T
Thu Jul 01 00:00:00 EDT 2021
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Chemico-biological interactions
Lu Y,Hao R,Hu Y,Wei Y,Xie Y,Shen Y,Rui Q,Yu G
Fri Oct 01 00:00:00 EDT 2021
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Journal of ethnopharmacology
Lin CE,Lin PY,Yang WC,Huang YS,Lin TY,Chen CM,Chen HS,Lee JA,Chen SM
Sun May 23 00:00:00 EDT 2021
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
OncoTargets and therapy
Chen Z,Zhang Y,Wu X,Zhang J,Xu W,Shen C,Zheng B
Fri Apr 22 00:00:00 EDT 2022
Lactobacillus casei relieves liver injury by regulating immunity and suppression of the enterogenic endotoxin-induced inflammatory response in rats cotreated with alcohol and iron.
Food science & nutrition
Li X,Han J,Liu Y,Liang H
Fri Oct 01 00:00:00 EDT 2021
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Journal of cellular physiology
Wang M,Liu H,Zhang X,Zhao W,Li D,Xu C,Wu Z,Xie F,Li X
Wed Sep 01 00:00:00 EDT 2021
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Mediators of inflammation
Liu L,Luo F,Lei K
Fri Jan 07 00:00:00 EST 2022
The long noncoding RNA KTN1-AS1 promotes bladder cancer tumorigenesis via KTN1 cis-activation and the consequent initiation of Rho GTPase-mediated signaling.
Clinical science (London, England : 1979)
Hu X,Xiang L,He D,Zhu R,Fang J,Wang Z,Cao K
Fri Feb 12 00:00:00 EST 2021
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Frontiers in oncology
Zhang Y,Sun Y,Ding L,Shi W,Ding K,Zhu Y
Tue May 18 00:00:00 EDT 2021
Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish.
Science advances
Zhang C,Lu T,Zhang Y,Li J,Tarique I,Wen F,Chen A,Wang J,Zhang Z,Zhang Y,Shi DL,Shao M
Sun Aug 01 00:00:00 EDT 2021
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Food & function
Liu XL,Zhao YC,Zhu HY,Wu M,Zheng YN,Yang M,Cheng ZQ,Ding CB,Liu WC
Mon Nov 29 00:00:00 EST 2021
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Cellular signalling
Xiong X,Xu W,Gong J,Wang L,Dai M,Chen G,Yuan L
Fri Jan 01 00:00:00 EST 2021
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Journal of Zhejiang University. Science. B
Xu A,Lee J,Zhao Y,Wang Y,Li X,Xu P
Thu Jul 15 00:00:00 EDT 2021
Identification of autophagic target RAB13 with small-molecule inhibitor in low-grade glioma via integrated multi-omics approaches coupled with virtual screening of traditional Chinese medicine databases.
Cell proliferation
Su W,Liao M,Tan H,Chen Y,Zhao R,Jin W,Zhu S,Zhang Y,He L,Liu B
Wed Dec 01 00:00:00 EST 2021
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
Cancer cell international
Li G,Wu Q,Gong L,Xu X,Cai J,Xu L,Zeng Y,He X,Wang Z
Tue Oct 26 00:00:00 EDT 2021
Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.
Journal of ethnopharmacology
Zhou F,Song Y,Liu X,Zhang C,Li F,Hu R,Huang Y,Ma W,Song K,Zhang M
Mon Nov 15 00:00:00 EST 2021
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response.
PLoS neglected tropical diseases
Li T,Liu H,Jiang N,Wang Y,Wang Y,Zhang J,Shen Y,Cao J
Mon Nov 01 00:00:00 EDT 2021
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Molecular brain
Wu H,Liu Y,Liu L,Meng Q,Du C,Li K,Dong S,Zhang Y,Li H,Zhang H
Wed Jul 14 00:00:00 EDT 2021
Method used to establish a large animal model of drug-induced acute kidney injury.
Experimental biology and medicine (Maywood, N.J.)
Wang SY,Zhang CY,Cai GY,Chen XM
Thu Apr 01 00:00:00 EDT 2021
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
American journal of translational research
Zhai W,Li Y,Luo Y,Gao W,Liu S,Han J,Geng J
Thu Nov 18 00:00:00 EST 2021
Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy.
Frontiers in pharmacology
Liu C,Li X,Shuai L,Dang X,Peng F,Zhao M,Xiong S,Liu Y,He Q
Tue May 04 00:00:00 EDT 2021
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Journal of biochemical and molecular toxicology
Man S,Wu Z,Sun R,Guan Q,Li Z,Zuo D,Zhang W,Wu Y
Sun Aug 01 00:00:00 EDT 2021
Synapse development is regulated by microglial THIK-1 K+ channels.
Proceedings of the National Academy of Sciences of the United States of America
Izquierdo P,Shiina H,Hirunpattarasilp C,Gillis G,Attwell D
Tue Oct 19 00:00:00 EDT 2021
HIF-1-regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation.
Proceedings of the National Academy of Sciences of the United States of America
Liu X,Xie P,Hao N,Zhang M,Liu Y,Liu P,Semenza GL,He J,Zhang H
Tue Nov 02 00:00:00 EDT 2021
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Stem cells (Dayton, Ohio)
Wu X,Wang X,Shan L,Zhou J,Zhang X,Zhu E,Yuan H,Wang B
Fri Oct 01 00:00:00 EDT 2021
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Experimental cell research
Wang D,Wei X,Chen X,Wang Q,Zhang J,Kalvakolanu DV,Guo B,Zhang L
Fri Oct 01 00:00:00 EDT 2021
Effect of combination therapy with neural stem cell transplantation and teramethylpyrazine in rats following acute spinal cord injury.
Neuroreport
Zhang H,Huang Z,Guo M,Meng L,Piao M,Zhang M,Yu H
Tue Nov 02 00:00:00 EDT 2021
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
International immunopharmacology
Cao Q,Luo J,Xiong Y,Liu Z,Ye Q
Thu Jul 01 00:00:00 EDT 2021
MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells.
Biomolecules
Fan Y,Arbab AAI,Zhang H,Yang Y,Lu X,Han Z,Yang Z
Mon Jan 25 00:00:00 EST 2021
Effect of Babao Dan on angiogenesis of gastric cancer in vitro by regulating VEGFA/VEGFR2 signaling pathway.
Translational cancer research
Guan JH,Cao ZY,Guan B,Wei LH,Peng J,Chen YQ,Sferra TJ,Sankararaman S,Zhan ZX,Lin JM
Mon Feb 01 00:00:00 EST 2021
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Frontiers in pharmacology
Dong M,Zhang X,Yu H,Wang Y,Chang Y,Sun C,Zhang J,Zhao N,Yu K,Sun G,Zhao G,Xu N,Liu W
Wed Nov 10 00:00:00 EST 2021
Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation.
International journal of molecular medicine
Zhao J,Chen J,Li YY,Xia LL,Wu YG
Wed Sep 01 00:00:00 EDT 2021
AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
International journal of biological sciences
Liu X,Hu Z,Qu J,Li J,Gong K,Wang L,Jiang J,Li X,He R,Duan L,Luo W,Xia C,Luo D
Wed Jan 19 00:00:00 EST 2022
PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation.
Cells
Shmakova A,Frost M,Batie M,Kenneth NS,Rocha S
Tue Jun 08 00:00:00 EDT 2021
ADAM15 Participates in Tick-Borne Encephalitis Virus Replication.
Journal of virology
Yang Q,Pei R,Wang Y,Zhou Y,Yang M,Chen X,Chen J
Thu Jan 28 00:00:00 EST 2021
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer.
Cell death & disease
He Y,Gan M,Wang Y,Huang T,Wang J,Han T,Yu B
Fri Apr 30 00:00:00 EDT 2021
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Hepatology (Baltimore, Md.)
Chandler RJ,Venturoni LE,Liao J,Hubbard BT,Schneller JL,Hoffmann V,Gordo S,Zang S,Ko CW,Chau N,Chiang K,Kay MA,Barzel A,Venditti CP
Tue Jun 01 00:00:00 EDT 2021
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Journal of pharmacological sciences
Xianjun F,Xirui X,Jie T,Huiwen M,Shaojun Z,Qiaoyun L,Yunxin L,Xuqun S
Sun Aug 01 00:00:00 EDT 2021
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
Oxidative medicine and cellular longevity
Zhang J,Zhao T,Wang C,Meng Q,Huo X,Wang C,Sun P,Sun H,Ma X,Wu J,Liu K
Tue Sep 07 00:00:00 EDT 2021
Deletion of ribosomal paralogs Rpl39 and Rpl39l compromises cell proliferation via protein synthesis and mitochondrial activity.
The international journal of biochemistry & cell biology
Zou Q,Qi H
Fri Oct 01 00:00:00 EDT 2021
Radiation-Induced Autophagy in Human Pancreatic Cancer Cells is Critically Dependent on G2 Checkpoint Activation: A Mechanism of Radioresistance in Pancreatic Cancer.
International journal of radiation oncology, biology, physics
Suzuki M,Anko M,Ohara M,Matsumoto KI,Hasegawa S
Wed Sep 01 00:00:00 EDT 2021
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood-Brain Barrier Disruption.
ACS infectious diseases
Yang R,Lv Y,Miao L,Zhang H,Qu X,Chen J,Xu B,Yang B,Fu J,Tan C,Chen H,Wang X
Fri Apr 09 00:00:00 EDT 2021
Novel Japanese encephalitis virus NS1-based vaccine: Truncated NS1 fused with E. coli heat labile enterotoxin B subunit.
EBioMedicine
Wan J,Wang T,Xu J,Ouyang T,Wang Q,Zhang Y,Weng S,Li Y,Wang Y,Xin X,Wang X,Li S,Kong L
Sat May 01 00:00:00 EDT 2021
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Frontiers in pharmacology
Liu Y,Zhong W,Zhang J,Chen W,Lu Y,Qiao Y,Zeng Z,Huang H,Cai S,Dong H
Sat Dec 11 00:00:00 EST 2021
Let-7 mediated airway remodelling in chronic obstructive pulmonary disease via the regulation of IL-6.
European journal of clinical investigation
Di T,Yang Y,Fu C,Zhang Z,Qin C,Sai X,Liu J,Hu C,Zheng M,Wu Y,Bian T
Thu Apr 01 00:00:00 EDT 2021
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Annals of translational medicine
Huang Z,Li X,Zhou T,Jiang Y,Shi JH
Wed Dec 01 00:00:00 EST 2021
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Environmental toxicology
Zeng R,Wang C,Wang W,Wang S
Wed Sep 01 00:00:00 EDT 2021
Probiotic-fermented black tartary buckwheat alleviates hyperlipidemia and gut microbiota dysbiosis in rats fed with a high-fat diet.
Food & function
Ren Y,Wu S,Xia Y,Huang J,Ye J,Xuan Z,Li P,Du B
Mon Jul 05 00:00:00 EDT 2021
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Journal of the science of food and agriculture
Liu H,Bai M,Xu K,Zhou J,Zhang X,Yu R,Huang R,Yin Y
Sat Jan 30 00:00:00 EST 2021
Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
International journal of cancer
Qu X,Zhao L,Wang M,Zhang R,Cheng L,Qiu L,Tong X,Cai S,Wei Q,Li Q
Thu Jul 01 00:00:00 EDT 2021
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments.
Frontiers in genetics
Zhou J,Zhang M,Zhang Y,Shi X,Liu L,Yao R
Wed Sep 29 00:00:00 EDT 2021
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.
Mutagenesis
Wang Y,Xia XB,Tang HZ,Cai JR,Shi XK,Ji HX,Yan XN,Xu T
Fri Aug 27 00:00:00 EDT 2021
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Frontiers in cell and developmental biology
Zhou B,Xiao M,Hu H,Pei X,Xue Y,Miao G,Wang J,Li W,Du Y,Zhang P,Wei T
Tue Aug 10 00:00:00 EDT 2021
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
International journal of medical sciences
Han J,Chen X,Xu J,Chu L,Li R,Sun N,Jiang Z,Liu H,Ge X,Zheng J,Yang J,Ikezoe T
Tue Mar 15 00:00:00 EDT 2022
Metformin attenuates H2O2-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway.
Experimental and therapeutic medicine
Yang K,Pei L,Zhou S,Tao L,Zhu Y
Mon Nov 01 00:00:00 EDT 2021
Protein kinase G signaling pathway is involved in sympathetically maintained pain by modulating ATP-sensitive potassium channels.
Regional anesthesia and pain medicine
Li H,Shang M,Liu L,Lin X,Hu J,Han Q,Xing J
Mon Nov 01 00:00:00 EDT 2021
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Environmental toxicology
Dong L,Liu Y,Wang D,Zhu K,Zou Z,Zhang A
Fri Oct 01 00:00:00 EDT 2021
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Frontiers in pharmacology
Jiang SL,Wang ZB,Zhu T,Jiang T,Fei JF,Liu C,Luo C,Cheng Y,Liu ZQ
Tue Sep 14 00:00:00 EDT 2021
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axis.
International immunopharmacology
Zhou Y,Gao Y,Zhang W,Chen Y,Jin M,Yang Z
Fri Oct 01 00:00:00 EDT 2021
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Cell death & disease
Lu D,Song Y,Yu Y,Wang D,Liu B,Chen L,Li X,Li Y,Cheng L,Lv F,Zhang P,Xing Y
Thu Aug 12 00:00:00 EDT 2021
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Oxidative medicine and cellular longevity
Xie MG,Fei YQ,Wang Y,Wang WY,Wang Z
Thu Sep 09 00:00:00 EDT 2021
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Journal of ethnopharmacology
Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F
Tue Aug 10 00:00:00 EDT 2021
IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats.
Frontiers in pharmacology
Wang J,Dai L,Yue X,Shen C,Li T,Long L,Zhi Y,Wang Y,Shen G,Shi C,Liu Y,Fang Q,Li W
Tue May 04 00:00:00 EDT 2021
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production.
Virus research
Shan Y,Tong Z,Jinzhu M,Yu L,Zecai Z,Chenhua W,Wenjing H,Siyu L,Nannan C,Siyu S,Tongtong B,Jiang H,Biaohui B,Xin J,Yulong Z,Zhanbo Z
Wed Sep 01 00:00:00 EDT 2021
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Aging
Cao W,Zeng Z,He Z,Lei S
Fri Feb 26 00:00:00 EST 2021
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats.
Toxicology and applied pharmacology
Yu L,Lu H,Yang X,Li R,Shi J,Yu Y,Ma C,Sun F,Zhang S,Zhang F
Mon Feb 01 00:00:00 EST 2021
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells.
Scientific reports
Meng P,Zhang YF,Zhang W,Chen X,Xu T,Hu S,Liang X,Feng M,Yang X,Ho M
Fri Jan 08 00:00:00 EST 2021
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Scientific reports
Tian S,Cao Y,Wang J,Bi Y,Zhong J,Meng X,Sun W,Yang R,Gan L,Wang X,Li H,Wang R
Tue May 18 00:00:00 EDT 2021
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin.
Oncogene
Cheng C,Pei X,Li SW,Yang J,Li C,Tang J,Hu K,Huang G,Min WP,Sang Y
Thu Apr 01 00:00:00 EDT 2021
The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
The Journal of biological chemistry
Liu X,Li F,Zhang J,Wang L,Wang J,Wen Z,Wang Z,Shuai L,Wang X,Ge J,Zhao D,Bu Z
Tue Aug 24 00:00:00 EDT 2021
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Frontiers in pharmacology
Wang T,Dong J,Yuan X,Wen H,Wu L,Liu J,Sui H,Deng W
Sun May 02 00:00:00 EDT 2021
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis.
The Journal of biological chemistry
Li F,Cai Y,Deng S,Yang L,Liu N,Chang X,Jing L,Zhou Y,Li H
Mon Nov 01 00:00:00 EDT 2021
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers.
PLoS pathogens
Owen RS,Ramarathinam SH,Bailey A,Gastaldello A,Hussey K,Skipp PJ,Purcell AW,Siddle HV
Mon Nov 01 00:00:00 EDT 2021
Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway.
Marine drugs
Pan N,Li ZC,Li ZH,Chen SH,Jiang MH,Yang HY,Liu YS,Hu R,Zeng YW,Dai LH,Liu L,Wang GL
Fri Dec 24 00:00:00 EST 2021
Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways.
Journal of inflammation research
Ye W,Yan Y,Tang Y,Dong X,Chen G,Kang J,Huang L,Xiong Q,Feng Z
Sat Apr 23 00:00:00 EDT 2022
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD.
BMC pulmonary medicine
Yang Y,Di T,Zhang Z,Liu J,Fu C,Wu Y,Bian T
Mon Apr 26 00:00:00 EDT 2021
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.
Biomedical journal
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Chiu CH,Wang LC
Wed Dec 01 00:00:00 EST 2021
SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway.
Life sciences
Luo Y,Huang Z,Mou T,Pu J,Li T,Li Z,Yang H,Yan P,Wu Z,Wu Q
Sat May 15 00:00:00 EDT 2021
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Frontiers in oncology
Qin T,Li J,Xiao Y,Wang X,Gong M,Wang Q,Zhu Z,Zhang S,Zhang W,Cao F,Han L,Wang Z,Ma Q,Sha H
Wed Apr 27 00:00:00 EDT 2022
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Frontiers in oncology
Guo W,Ma X,Fu Y,Liu C,Liu Q,Hu F,Miao H,Zhang T,Liu Y,Han MH,You F,Yang Y,Zheng W
Wed Apr 21 00:00:00 EDT 2021
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
Nature communications
Huang X,Pan L,Zuo Z,Li M,Zeng L,Li R,Ye Y,Zhang J,Wu G,Bai R,Zhuang L,Wei L,Zheng Y,Su J,Deng J,Deng S,Zhang S,Zhu S,Che X,Wang C,Wu C,Chen R,Lin D,Zheng J
Tue Jun 22 00:00:00 EDT 2021
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Cell reports
Karki R,Sundaram B,Sharma BR,Lee S,Malireddi RKS,Nguyen LN,Christgen S,Zheng M,Wang Y,Samir P,Neale G,Vogel P,Kanneganti TD
Tue Oct 19 00:00:00 EDT 2021
Hsa-miR-335 enhances cell migration and invasion in lung adenocarcinoma through targeting Copine-1.
MedComm
Wang Y,Zhang J,Zhong LY,Huang SJ,Yu NN,Ouyang L,Niu YL,Chen JX,Lu CH,He QY
Wed Dec 01 00:00:00 EST 2021
Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes.
Frontiers in physiology
Meng TT,Wang W,Meng FL,Wang SY,Wu HH,Chen JM,Zheng Y,Wang GX,Zhang MX,Li Y,Su GH
Tue Jun 29 00:00:00 EDT 2021
Chemical Constituents from the Rhizome of Ligusticum chuanxiong Hort. and Their Nrf2 Inducing Activity.
Chemistry & biodiversity
Zhang K,Fang KL,Wang T,Xu LT,Zhao Y,Wang XN,Xiang L,Shen T
Mon Nov 01 00:00:00 EDT 2021
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
The journal of physiological sciences : JPS
Mao Y,Jiang L
Wed Sep 15 00:00:00 EDT 2021
ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1.
Journal of oncology
Guan X,Guan X,Qin J,Qin L,Shi W,Jiao Z
Fri Dec 17 00:00:00 EST 2021
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Biochemical pharmacology
Sun M,Sheng H,Wu T,Song J,Sun H,Wang Y,Wang J,Li Z,Zhao H,Tan J,Li Y,Chen G,Huang Q,Zhang Y,Lan B,Liu S,Shan C,Zhang S
Fri Oct 01 00:00:00 EDT 2021
Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors.
Cellular and molecular life sciences : CMLS
Tan Y,Zhou X,Gong Y,Gou K,Luo Y,Jia D,Dai L,Zhao Y,Sun Q
Fri Dec 31 00:00:00 EST 2021
Hypericin-mediated photodynamic therapy inhibits growth of colorectal cancer cells via inducing S phase cell cycle arrest and apoptosis.
European journal of pharmacology
Hu J,Song J,Tang Z,Wei S,Chen L,Zhou R
Sat Jun 05 00:00:00 EDT 2021
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Cell death & disease
Chen G,Zeng H,Li X,Liu J,Li Z,Xu R,Ma Y,Liu C,Xue B
Sat Oct 30 00:00:00 EDT 2021
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
The international journal of biochemistry & cell biology
Wang Z,Li Y,Yao J,Yu S,Yu H,Men L,Du J
Wed Dec 01 00:00:00 EST 2021
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
American journal of physiology. Cell physiology
Kang K,Liao X,Li Q,Chen J,Niu Y,Zeng Y,Xia S,Zeng L,Liu S,Gou D
Mon Feb 01 00:00:00 EST 2021
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
The Journal of pharmacology and experimental therapeutics
Wang Q,Li Z,Liu K,Liu J,Chai S,Chen G,Wen S,Ming T,Wang J,Ma Y,Zeng H,Liu C,Xue B
Mon Feb 01 00:00:00 EST 2021
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
In vitro cellular & developmental biology. Animal
Zhang C,Gao J,Zhu S
Wed Dec 01 00:00:00 EST 2021
Systematic identification of autophagy-related proteins in Aedes albopictus.
PloS one
Wang Y,Qiao J,Zhang D,Zhong C,Wang S,Li X,Feng L,Shi S,Wang B,Liu Q
Wed Jun 16 00:00:00 EDT 2021
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Cell biology international
Bai Z,Ding N,Ge J,Wang Y,Wang L,Wu N,Wei Q,Xu S,Liu X,Zhou G
Fri Jan 01 00:00:00 EST 2021
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Aging
Yang RZ,Zheng HL,Xu WN,Zheng XF,Li B,Jiang LS,Jiang SD
Mon Feb 01 00:00:00 EST 2021
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Human & experimental toxicology
Dong Z,Bian L,Wang YL,Sun LM
Wed Sep 01 00:00:00 EDT 2021
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Bone & joint research
Liu ZM,Lu CC,Shen PC,Chou SH,Shih CL,Chen JC,Tien YC
Sun Aug 01 00:00:00 EDT 2021
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Cellular signalling
Peng YF,Lin H,Liu DC,Zhu XY,Huang N,Wei YX,Li L
Sun Aug 01 00:00:00 EDT 2021
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Cell
Truong ME,Bilekova S,Choksi SP,Li W,Bugaj LJ,Xu K,Reiter JF
Thu May 27 00:00:00 EDT 2021
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Neuroreport
Hu J,Chen X,Cheng J,Kong F,Xia H,Wu J
Wed Aug 04 00:00:00 EDT 2021
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Respiratory research
Newton DA,Lottes RG,Ryan RM,Spyropoulos DD,Baatz JE
Thu Oct 28 00:00:00 EDT 2021
Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity.
Journal of virology
Liang W,Zhang Y,Li M,Al-Shaebi F,Li J,Zhang J,Wei L
Mon Jul 12 00:00:00 EDT 2021
Irisin Association with Ki-67, MCM3 and MT-I/II in Squamous Cell Carcinomas of the Larynx.
Biomolecules
Pinkowska A,Nowinska K,Ciesielska U,Podhorska-Okolow M
Thu Dec 30 00:00:00 EST 2021
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Journal of cellular and molecular medicine
Zhang L,Jiang X,Liu N,Li M,Kang J,Chen L,Tang J,Dong S,Lu F,Zhang W
Wed Sep 01 00:00:00 EDT 2021
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.
Frontiers in pharmacology
Zhu X,Li T,Hu E,Duan L,Zhang C,Wang Y,Tang T,Yang Z,Fan R
Fri Feb 04 00:00:00 EST 2022
The Cancer-Testis Long Non-coding RNA PCAT6 Facilitates the Malignant Phenotype of Ovarian Cancer by Sponging miR-143-3p.
Frontiers in cell and developmental biology
Tan X,Shao Y,Teng Y,Liu S,Li W,Xue L,Cao Y,Sun C,Zhang J,Han J,Wu X,Xu H,Xie K
Sat Feb 27 00:00:00 EST 2021
Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.
European journal of pharmacology
Dong R,Wang X,Wang L,Wang C,Huang K,Fu T,Liu K,Wu J,Sun H,Meng Q
Tue Jan 05 00:00:00 EST 2021
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Shu Y,Huang J,Gao M,Gan S,Zhu S,Xu S,Yang Z,Liao Y,Lu W
Tue Jun 01 00:00:00 EDT 2021
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells†.
Biology of reproduction
Murata H,Kunii H,Kusama K,Sakurai T,Bai H,Kawahara M,Takahashi M
Mon Nov 15 00:00:00 EST 2021
BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery.
Frontiers in pharmacology
Xiao W,He Z,Luo W,Feng D,Wang Y,Tang T,Yang A,Luo J
Wed May 26 00:00:00 EDT 2021
Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis.
BioMed research international
Cheng Z,Gao S,Liang X,Lian C,Chen J,Fang C
Tue Oct 19 00:00:00 EDT 2021
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells.
Redox biology
Ye Z,Zhuo Q,Hu Q,Xu X,Zhang Z,Xu W,Liu W,Fan G,Qin Y,Yu X,Ji S
Fri Jan 01 00:00:00 EST 2021
NLRP3 inflammasome signal pathway involves in Vibrio harveyi-induced inflammatory response in murine peritoneal macrophages in vitro.
Acta biochimica et biophysica Sinica
Yu G,Wang J,Zhang W,Yang Q,Liu G,Wang L,Bello BK,Zhang X,Zhang T,Fan H,Zhao P,Liang W,Dong J
Wed Dec 08 00:00:00 EST 2021
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
International immunopharmacology
Schlichtner S,Meyer NH,Yasinska IM,Aliu N,Berger SM,Gibbs BF,Fasler-Kan E,Sumbayev VV
Mon Nov 01 00:00:00 EDT 2021
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
Metabolites
Del Re A,Corpetti C,Pesce M,Seguella L,Steardo L,Palenca I,Rurgo S,De Conno B,Sarnelli G,Esposito G
Thu Sep 02 00:00:00 EDT 2021
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Molecular therapy. Nucleic acids
Li D,Wang X,Dang Y,Zhang X,Zhao S,Lu G,Chan WY,Leung PCK,Qin Y
Fri Mar 05 00:00:00 EST 2021
Dietary hawthorn-leaves flavonoids improves ovarian function and liver lipid metabolism in aged breeder hens.
Poultry science
Dai H,Lv Z,Huang Z,Ye N,Li S,Jiang J,Cheng Y,Shi F
Wed Dec 01 00:00:00 EST 2021
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
Anticancer research
Motomura H,Tamori S,Yatani MA,Namiki A,Onaga C,Ozaki A,Takasawa R,Mano Y,Sato T,Hara Y,Sato K,Xiong Y,Harada Y,Hanawa T,Tanuma SI,Sasaki K,Ohno S,Akimoto K
Wed Dec 01 00:00:00 EST 2021
HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.
Journal of neuroinflammation
Li L,Li Y,He B,Li H,Ji H,Wang Y,Zhu Z,Hu Y,Zhou Y,Yang T,Sun C,Yuan Y,Wang Y
Thu Sep 16 00:00:00 EDT 2021
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Bioactive materials
Sun N,Dou X,Tang Z,Zhang D,Ni N,Wang J,Gao H,Ju Y,Dai X,Zhao C,Gu P,Ji J,Feng C
Thu Apr 01 00:00:00 EDT 2021
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.
Veterinary microbiology
Zhu H,Yan J,Liu X,Li L,Liu W,Wang X,Jiang P,Bai J
Sat May 01 00:00:00 EDT 2021
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
International immunopharmacology
Yu B,Jin XQ,Yu WY,Dong YY,Ying HZ,Yu CH
Wed Dec 01 00:00:00 EST 2021
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
European journal of pharmacology
Wang J,Chen R,Liu C,Wu X,Zhang Y
Fri Oct 15 00:00:00 EDT 2021
A naturally occurring FXR agonist, alisol B 23-acetate, protects against renal ischemia-reperfusion injury.
American journal of physiology. Renal physiology
Luan ZL,Ming WH,Sun XW,Zhang C,Zhou Y,Zheng F,Yang YL,Guan YF,Zhang XY
Mon Nov 01 00:00:00 EDT 2021
IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection.
Clinical & translational immunology
Li J,Cheng L,Jia H,Liu C,Wang S,Liu Y,Shen Y,Wu S,Meng F,Zheng B,Yang C,Jiang W
Thu Apr 28 00:00:00 EDT 2022
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH2 Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma.
International journal of nanomedicine
Wan Z,Li C,Gu J,Qian J,Zhu J,Wang J,Li Y,Jiang J,Chen H,Luo C
Wed Nov 24 00:00:00 EST 2021
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Environmental toxicology
Ren F,Xu X,Xu J,Mei Y,Zhang J,Wang X,Li F
Wed Sep 01 00:00:00 EDT 2021
Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation.
Oxidative medicine and cellular longevity
Zhu JJ,Yu BY,Huang XK,He MZ,Chen BW,Chen TT,Fang HY,Chen SQ,Fu XQ,Li PJ,Lin ZL,Zhu JH
Wed Nov 24 00:00:00 EST 2021
Tetramethylpyrazine Alleviates Behavioral and Psychological Symptoms of Dementia Through Facilitating Hippocampal Synaptic Plasticity in Rats With Chronic Cerebral Hypoperfusion.
Frontiers in neuroscience
Tan Z,Qiu J,Zhang Y,Yang Q,Yin X,Li J,Liu G,Li H,Yang G
Wed May 26 00:00:00 EDT 2021
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Frontiers in cell and developmental biology
Liang X,He M,Zhu B,Zhu Y,He X,Liu D,Wei Q
Wed Sep 08 00:00:00 EDT 2021
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Stem cell research & therapy
Liu J,He J,Ge L,Xiao H,Huang Y,Zeng L,Jiang Z,Lu M,Hu Z
Thu Jul 22 00:00:00 EDT 2021
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Oxidative medicine and cellular longevity
Du Y,Zhong F,Cheng H,Li T,Chen Y,Tan P,Huang M,Liang T,Liu Y,Xia X,Fu W
Thu Feb 17 00:00:00 EST 2022
Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway.
Frontiers in pharmacology
Li L,Yin M,Hu L,Tian X,He X,Zhao C,Li Y,Li Q,Li X
Fri Oct 22 00:00:00 EDT 2021
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Cell death & disease
Wang Y,Lu H,Sun L,Chen X,Wei H,Suo C,Feng J,Yuan M,Shen S,Jia W,Wang Y,Zhang H,Li Z,Zhong X,Gao P
Sat Oct 02 00:00:00 EDT 2021
MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity.
Frontiers in immunology
Liang S,Huang G,Wu T,Peng Y,Liu X,Ji X,Sha W,Wang F,Shen L,Shen H
Fri Feb 04 00:00:00 EST 2022
Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins.
Talanta
Li H,Xing S,Xu J,He Y,Lai Y,Wang Y,Zhang G,Guo S,Deng M,Zeng M,Liu W
Fri Jan 01 00:00:00 EST 2021
The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.
Ecotoxicology and environmental safety
Li S,Ma Y,Liang Y,Liang N,Ye S,Xiao F
Fri May 07 00:00:00 EDT 2021
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Environmental science and pollution research international
Lu J,Liu M,Fan Y,Zheng H,Guan S
Thu Jul 01 00:00:00 EDT 2021
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer.
Theranostics
Wu B,Chang N,Xi H,Xiong J,Zhou Y,Wu Y,Wu S,Wang N,Yi H,Song Y,Chen L,Zhang J
Tue Jul 27 00:00:00 EDT 2021
LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p.
BMC cancer
Zhang J,Lv W,Liu Y,Fu W,Chen B,Ma Q,Gao X
Wed Jun 02 00:00:00 EDT 2021
β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer.
Cell & bioscience
Hu J,Lu R,Zhang Y,Li W,Hu Q,Chen C,Liu Z,Zhang W,Chen L,Xu R,Luo J,McLeod HL,He Y
Mon Sep 20 00:00:00 EDT 2021
Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.
Experimental and therapeutic medicine
Wang Y,Yin CP,Tai YL,Zhao ZJ,Hou ZY,Wang QJ
Mon Mar 01 00:00:00 EST 2021
MiR-362 suppresses cervical cancer progression via directly targeting BAP31 and activating TGFβ/Smad pathway.
Cancer medicine
Yang S,Sun Y,Jiang D,Wang J,Dang E,Li Z,Zhou J,Lu Y,Shi J,Tao L,Wang J,Jin B,Zheng L,Yang K
Fri Jan 01 00:00:00 EST 2021
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Environmental toxicology
Wu B,Yang C,Fang Y,Ding W,Zhang Y
Sat May 01 00:00:00 EDT 2021
Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway.
International journal of medical sciences
Zhang L,Cai Q,Lin S,Chen B,Jia B,Ye R,Weygant N,Chu J,Peng J
Wed Nov 03 00:00:00 EDT 2021
EZH2 regulates expression of FOXC1 by mediating H3K27me3 in breast cancers.
Acta pharmacologica Sinica
Zheng XJ,Li W,Yi J,Liu JY,Ren LW,Zhu XM,Liu SW,Wang JH,Du GH
Thu Jul 01 00:00:00 EDT 2021
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
Frontiers in pharmacology
Chen P,Wen Z,Shi W,Li Z,Chen X,Gao Y,Xu S,Gong Q,Deng J
Tue Oct 26 00:00:00 EDT 2021
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Molecular medicine reports
Huang H,Liu K,Ou H,Qian X,Wan J
Tue Jun 01 00:00:00 EDT 2021
Differential mitochondrial proteomic analysis of A549 cells infected with avian influenza virus subtypes H5 and H9.
Virology journal
Yang Y,Zhang Y,Yang C,Fang F,Wang Y,Chang H,Chen Z,Chen P
Thu Feb 18 00:00:00 EST 2021
Effect of circular RNA, mmu_circ_0000296, on neuronal apoptosis in chronic cerebral ischaemia via the miR-194-5p/Runx3/Sirt1 axis.
Cell death discovery
Huang K,Yang C,Zheng J,Liu X,Liu J,Che D,Xue Y,An P,Wang D,Ruan X,Yu B
Sat May 29 00:00:00 EDT 2021
Fludarabine Inhibits Infection of Zika Virus, SFTS Phlebovirus, and Enterovirus A71.
Viruses
Gao C,Wen C,Li Z,Lin S,Gao S,Ding H,Zou P,Xing Z,Yu Y
Tue Apr 27 00:00:00 EDT 2021
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity.
Journal of agricultural and food chemistry
Jin M,Wei Y,Yu H,Ma X,Yan S,Zhao L,Ding L,Cheng J,Feng H
Wed Nov 10 00:00:00 EST 2021
Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.
Frontiers in pharmacology
Hu W,Wang R,Sun B
Tue Apr 06 00:00:00 EDT 2021
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.
Cell death & disease
Chen Q,Liu Q,Zhang Y,Li S,Yi S
Thu Apr 22 00:00:00 EDT 2021
Proteomic Analysis of the Alterations in Follicular Fluid Proteins During Oocyte Maturation in Humans.
Frontiers in endocrinology
Wang C,Fei X,Zhang H,Zhou W,Cheng Z,Feng Y
Thu Mar 31 00:00:00 EDT 2022
miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.
Journal of cellular physiology
Guo Q,Zhu X,Wei R,Zhao L,Zhang Z,Yin X,Zhang Y,Chu C,Wang B,Li X
Mon Mar 01 00:00:00 EST 2021
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
Oncogene
Liu C,Zhou X,Long Q,Zeng H,Sun Q,Chen Y,Wu D,Liu L
Fri Jan 01 00:00:00 EST 2021
An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco).
Ecotoxicology and environmental safety
Wang Y,Xiao X,Wang F,Yang Z,Yue J,Shi J,Ke F,Xie Z,Fan Y
Fri Jan 01 00:00:00 EST 2021
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells.
Cancer letters
Zheng X,Liu J,Li X,Tian R,Shang K,Dong X,Cao B
Thu Jan 28 00:00:00 EST 2021
Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
Cancers
Shindo H,Harada-Shoji N,Ebata A,Sato M,Soga T,Miyashita M,Tada H,Kawai M,Kosaka S,Onuki K,Usami S,Furumoto S,Hayashi S,Abe T,Suzuki T,Ishida T,Sasano H
Mon Aug 30 00:00:00 EDT 2021
Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy.
Scientific reports
Wang F,Sun H,Zuo B,Shi K,Zhang X,Zhang C,Sun D
Wed Aug 11 00:00:00 EDT 2021
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Nature communications
Hou J,Han L,Zhao Z,Liu H,Zhang L,Ma C,Yi F,Liu B,Zheng Y,Gao C
Thu May 20 00:00:00 EDT 2021
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Aging cell
Xiong L,Ye X,Chen Z,Fu H,Li S,Xu P,Yu J,Wen L,Gao R,Fu Y,Qi H,Kilby MD,Saffery R,Baker PN,Tong C
Fri Oct 01 00:00:00 EDT 2021
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Journal of applied toxicology : JAT
Gu M,Dai Z,Yan X,Ma J,Niu Y,Lan W,Wang X,Xu Q
Sat May 01 00:00:00 EDT 2021
Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma.
The Journal of pharmacy and pharmacology
Xue D,Zhou X,Qiu J
Mon Mar 01 00:00:00 EST 2021
TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis.
Frontiers in oncology
Zhu X,Zhuo Y,Wu S,Chen Y,Ye J,Deng Y,Feng Y,Liu R,Cai S,Zou Z,Wang B,Wu CL,Zeng G,Zhong W
Thu Oct 21 00:00:00 EDT 2021
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Nutrients
Huang Y,Tocmo R,Nauman MC,Haughan MA,Johnson JJ
Fri Sep 10 00:00:00 EDT 2021
TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Nature communications
Qin Y,Li Q,Liang W,Yan R,Tong L,Jia M,Zhao C,Zhao W
Mon Aug 09 00:00:00 EDT 2021
Differential expression of protein disulfide isomerase (PDI) in regulating endometrial receptivity in humans.
Reproductive biology
Fernando SR,Kottawatta KSA,Jiang L,Chen X,Cheng KW,Wong BP,Ng EH,Yeung WS,Lee KF
Tue Jun 01 00:00:00 EDT 2021
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
International journal of medical sciences
Lu L,Zha Z,Zhang P,Li D,Liu G
Wed Mar 09 00:00:00 EST 2022
Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
Wu L,Kang Z,Qiao N,Wang C,Tang Z
Sat May 01 00:00:00 EDT 2021
Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.
Journal of medicinal chemistry
Zhang Z,Guo Z,Xu X,Cao D,Yang H,Li Y,Shi Q,Du Z,Guo X,Wang X,Chen D,Zhang Y,Chen L,Zhou K,Li J,Geng M,Huang X,Xiong B
Thu Nov 25 00:00:00 EST 2021
Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.
ACS applied materials & interfaces
Wu L,Wu LP,Wu J,Sun J,He Z,Rodríguez-Rodríguez C,Saatchi K,Dailey LA,Häfeli UO,Cun D,Yang M
Wed Jan 27 00:00:00 EST 2021
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.
Journal of neuroinflammation
Xu J,Wu S,Wang J,Wang J,Yan Y,Zhu M,Zhang D,Jiang C,Liu T
Thu May 06 00:00:00 EDT 2021
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Nature immunology
Zheng M,Karki R,Williams EP,Yang D,Fitzpatrick E,Vogel P,Jonsson CB,Kanneganti TD
Thu Jul 01 00:00:00 EDT 2021
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.
JCI insight
Min Q,Wang Y,Wu Q,Li X,Teng H,Fan J,Cao Y,Fan P,Zhan Q
Wed Sep 08 00:00:00 EDT 2021
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway.
Redox biology
Jia SZ,Xu XW,Zhang ZH,Chen C,Chen YB,Huang SL,Liu Q,Hoffmann PR,Song GL
Mon Nov 01 00:00:00 EDT 2021
Taohong Siwu-Containing Serum Enhances Angiogenesis in Rat Aortic Endothelial Cells by Regulating the VHL/HIF-1α/VEGF Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Tang Z,Li W,Xie H,Jiang S,Pu Y,Xiong H
Thu Apr 28 00:00:00 EDT 2022
d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.
Biochemical and biophysical research communications
Zhang Z,Zhou X,Liu J,Zheng Y,Wu Y,Yang W,Yi Y,Liu J,Wang J
Fri Oct 08 00:00:00 EDT 2021
Grouper TRAF5 exerts negative regulation on antiviral immune response against iridovirus.
Fish & shellfish immunology
Sun M,Wu S,Zhang X,Zhang L,Kang S,Qin Q,Wei J
Sun Aug 01 00:00:00 EDT 2021
Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.
Journal of virology
Liang J,Ruthel G,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Jaladanki CK,Fan H,Freedman BD,Harty RN
Thu Mar 25 00:00:00 EDT 2021
Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress.
Oxidative medicine and cellular longevity
Ni B,Chen Z,Shu L,Shao Y,Huang Y,Tamrat NE,Wei Z,Shen B
Thu Dec 30 00:00:00 EST 2021
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Biochemical and biophysical research communications
Wu HH,Meng TT,Chen JM,Meng FL,Wang SY,Liu RH,Chen JN,Ning B,Li Y,Su GH
Fri May 14 00:00:00 EDT 2021
Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis.
Frontiers in oncology
Wang Y,Wei Q,Chen Y,Long S,Yao Y,Fu K
Fri Apr 30 00:00:00 EDT 2021
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Metabolism: clinical and experimental
Teng F,Jiang J,Zhang J,Yuan Y,Li K,Zhou B,Zhou X,Liu W,Zhang P,Liu D,Zheng M,Lu Y,Zhang H
Thu Apr 01 00:00:00 EDT 2021
Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer.
International immunopharmacology
Dong X,Yang Q,Gu J,Lv S,Song D,Chen D,Song J,Zhang X,Huang D
Fri Jan 01 00:00:00 EST 2021
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway.
The Journal of cell biology
Shen JL,Fortier TM,Wang R,Baehrecke EH
Mon Nov 01 00:00:00 EDT 2021
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Experimental and therapeutic medicine
Lele W,Lei L,Liting Q
Tue Jun 01 00:00:00 EDT 2021
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Ecotoxicology and environmental safety
Jin H,Hou J,Meng X,Ma T,Wang B,Liu Z,Sha X,Ding J,Han X
Fri Jan 15 00:00:00 EST 2021
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
International journal of molecular sciences
Bian Q,Chen B,Weng B,Chu D,Tang X,Yan S,Yin Y,Ran M
Mon Aug 30 00:00:00 EDT 2021
Identifying SLC27A5 as a potential prognostic marker of hepatocellular carcinoma by weighted gene co-expression network analysis and in vitro assays.
Cancer cell international
Zhang F,Xue M,Jiang X,Yu H,Qiu Y,Yu J,Yang F,Bao Z
Wed Mar 17 00:00:00 EDT 2021
Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury.
PloS one
Carlisle RE,Farooqi S,Zhang MC,Liu S,Lu C,Phan A,Brimble E,Dickhout JG
Wed Jan 05 00:00:00 EST 2022
Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
The Journal of pharmacy and pharmacology
Yang X,Gao M,Miao M,Jiang C,Zhang D,Yin Z,Ni Y,Chen J,Zhang J
Thu Mar 04 00:00:00 EST 2021
Layer-specific strain for assessing the effect of naringin on systolic myocardial dysfunction induced by sepsis and its underlying mechanisms.
The Journal of international medical research
Sun LJ,Qiao W,Xiao YJ,Ren WD
Fri Jan 01 00:00:00 EST 2021
A conserved ubiquitin- and ESCRT-dependent pathway internalizes human lysosomal membrane proteins for degradation.
PLoS biology
Zhang W,Yang X,Chen L,Liu YY,Venkatarangan V,Reist L,Hanson P,Xu H,Wang Y,Li M
Thu Jul 01 00:00:00 EDT 2021
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Life sciences
Zhang L,Zheng Y,Zeng L,Zhang F,Che D,Cao Z,Huang C,Xian L,Zhang X,Zhang H,Guo Z
Mon Nov 15 00:00:00 EST 2021
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
PLoS pathogens
Sarute N,Cheng H,Yan Z,Salas-Briceno K,Richner J,Rong L,Ross SR
Tue Jun 01 00:00:00 EDT 2021
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Frontiers in pharmacology
Xin J,Cheng W,Yu Y,Chen J,Zhang X,Shao S
Wed Feb 16 00:00:00 EST 2022
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.
Cells
Kashyap S,Rabbani M,de Lima I,Kondrachuk O,Patel R,Shafiei MS,Mukker A,Rajakumar A,Gupta MK
Wed Dec 08 00:00:00 EST 2021
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
Journal of hazardous materials
Xia D,Yang L,Li Y,Chen J,Zhang X,Wang H,Zhai S,Jiang X,Meca G,Wang S,Huang L,Zhu S,Fu Y,Ma W,Zhu Y,Ye H,Wang W
Mon Jul 05 00:00:00 EDT 2021
Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ma X,Li X,Di Q,Zhao X,Zhang R,Xiao Y,Sun P,Tang H,Quan J,Xiao W,Chen W
Tue Jun 01 00:00:00 EDT 2021
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
ACS biomaterials science & engineering
Shi M,Wang Y,Zhao X,Zhang J,Hu H,Qiao M,Zhao X,Chen D
Mon Jul 12 00:00:00 EDT 2021
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Frontiers in neurology
Pang J,Wu Y,Peng J,Yang P,Chen L,Jiang Y
Wed Sep 29 00:00:00 EDT 2021
Ceruloplasmin correlates with immune infiltration and serves as a prognostic biomarker in breast cancer.
Aging
Chen F,Han B,Meng Y,Han Y,Liu B,Zhang B,Chang Y,Cao P,Fan Y,Tan K
Thu Aug 19 00:00:00 EDT 2021
β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.
Frontiers in immunology
Koda S,Zhang B,Zhou QY,Xu N,Li J,Liu JX,Liu M,Lv ZY,Wang JL,Shi Y,Gao S,Yu Q,Li XY,Xu YH,Chen JX,Tekengne BOT,Adzika GK,Tang RX,Sun H,Zheng KY,Yan C
Fri Feb 11 00:00:00 EST 2022
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Biochemical and biophysical research communications
Fu X,Wu M,Zhou X
Fri Jun 11 00:00:00 EDT 2021
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish.
Neuropeptides
Kawabe M,Hayashi A,Komatsu M,Inui A,Shiozaki K
Tue Jun 01 00:00:00 EDT 2021
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.
Signal transduction and targeted therapy
Zhang D,Shi R,Xiang W,Kang X,Tang B,Li C,Gao L,Zhang X,Zhang L,Dai R,Miao H
Fri Mar 27 00:00:00 EDT 2020
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.
Cell stem cell
Cai EY,Kufeld MN,Schuster S,Arora S,Larkin M,Germanos AA,Hsieh AC,Beronja S
Thu Aug 06 00:00:00 EDT 2020
Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly.
Neuron
Tsai MH,Muir AM,Wang WJ,Kang YN,Yang KC,Chao NH,Wu MF,Chang YC,Porter BE,Jansen LA,Sebire G,Deconinck N,Fan WL,Su SC,Chung WH,Almanza Fuerte EP,Mehaffey MG,Ng CC,Chan CK,Lim KS,Leventer RJ,Lockhart PJ,Riney K,Damiano JA,Hildebrand MS,Mirzaa GM,Dobyns WB,Berkovic SF,Scheffer IE,Tsai JW,Mefford HC
Wed Apr 22 00:00:00 EDT 2020
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
EMBO molecular medicine
Kahlfuss S,Kaufmann U,Concepcion AR,Noyer L,Raphael D,Vaeth M,Yang J,Pancholi P,Maus M,Muller J,Kozhaya L,Khodadadi-Jamayran A,Sun Z,Shaw P,Unutmaz D,Stathopulos PB,Feist C,Cameron SB,Turvey SE,Feske S
Fri Aug 07 00:00:00 EDT 2020
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Metabolism: clinical and experimental
Mooli RGR,Mukhi D,Watt M,Edmunds L,Xie B,Capooci J,Reslink M,Eze C,Mills A,Stolz DB,Jurczak M,Ramakrishnan SK
Mon Jun 01 00:00:00 EDT 2020
The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.
EMBO reports
Yang D,Wu X,Zhou Y,Wang W,Wang Z
Thu Sep 03 00:00:00 EDT 2020
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
PLoS pathogens
Liu J,Jin L,Chen X,Yuan Y,Zuo Y,Miao Y,Feng Q,Zhang H,Huang F,Guo T,Zhang L,Zhu L,Qian F,Zhu C,Zheng H
Wed Jan 01 00:00:00 EST 2020
Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation.
Frontiers in cell and developmental biology
Hua Y,Wu J,Fu M,Liu J,Li X,Zhang B,Zhao W,Wan C
Tue Jan 12 00:00:00 EST 2021
Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang C,Zhang X,Wang J,Di F,Xue Y,Lin X,Zhang Y,Zhang H,Zhang Z,Gu Y
Sat Aug 01 00:00:00 EDT 2020
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhu Q,Dong H,Bukhari AA,Zhao A,Li M,Sun Y,Zhang X,Cao C,Su D,Liang X
Sun Mar 01 00:00:00 EST 2020
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.
Journal of immunology (Baltimore, Md. : 1950)
Zhang M,Fu M,Li M,Hu H,Gong S,Hu Q
Tue Sep 01 00:00:00 EDT 2020
Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells.
Journal of cellular and molecular medicine
Wang X,Shao X,Gu L,Jiang K,Wang S,Chen J,Fang J,Guo X,Yuan M,Shi J,Ding C,Meng S,Xu Q
Wed Apr 01 00:00:00 EDT 2020
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.
Journal of cell science
Zheng D,Sussman JH,Jeon MP,Parrish ST,MacMullan MA,Delfarah A,Graham NA
Thu Apr 09 00:00:00 EDT 2020
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
Breast cancer research and treatment
Guo S,Zhang C,Mottamal M,Hossain A,Liu J,Wang G
Wed Apr 01 00:00:00 EDT 2020
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
Neuro-degenerative diseases
Zhang M,He Q,Chen G,Li PA
Thu Oct 14 00:00:00 EDT 2021
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Animals : an open access journal from MDPI
Sun N,Zhang Y,Hou Y,Yi Y,Guo J,Zheng X,Sun P,Sun Y,Khan A,Li H
Wed Nov 04 00:00:00 EST 2020
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Journal of food science
Ou S,Fang Y,Tang H,Wu T,Chen L,Jiang M,Zhou L,Xu J,Guo K
Thu Oct 01 00:00:00 EDT 2020
Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
Cell proliferation
Hao Y,Huang Y,Chen J,Li J,Yuan Y,Wang M,Han L,Xin X,Wang H,Lin D,Peng F,Yu F,Zheng C,Shen C
Sat Aug 01 00:00:00 EDT 2020
Molecular mechanism of targeted inhibition of HMGA2 via miRNAlet-7a in proliferation and metastasis of laryngeal squamous cell carcinoma.
Bioscience reports
Ma LJ,Wu J,Zhou E,Yin J,Xiao XP
Fri Jun 26 00:00:00 EDT 2020
Integrative Proteomic Characterization of Human Lung Adenocarcinoma.
Cell
Xu JY,Zhang C,Wang X,Zhai L,Ma Y,Mao Y,Qian K,Sun C,Liu Z,Jiang S,Wang M,Feng L,Zhao L,Liu P,Wang B,Zhao X,Xie H,Yang X,Zhao L,Chang Y,Jia J,Wang X,Zhang Y,Wang Y,Yang Y,Wu Z,Yang L,Liu B,Zhao T,Ren S,Sun A,Zhao Y,Ying W,Wang F,Wang G,Zhang Y,Cheng S,Qin J,Qian X,Wang Y,Li J,He F,Xiao T,Tan M
Thu Jul 09 00:00:00 EDT 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Signal transduction and targeted therapy
Zheng Y,Zhuang MW,Han L,Zhang J,Nan ML,Zhan P,Kang D,Liu X,Gao C,Wang PH
Mon Dec 28 00:00:00 EST 2020
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway.
Cancer management and research
Guo G,Dai S,Chen Q
Thu Apr 14 00:00:00 EDT 2022
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal.
The journal of headache and pain
Niu Y,Zeng X,Zhao L,Zhou Y,Qin G,Zhang D,Fu Q,Zhou J,Chen L
Fri Dec 04 00:00:00 EST 2020
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
International immunopharmacology
Wang M,Zhang J,Zhao H,Wan D,Jiang Z
Wed Apr 01 00:00:00 EDT 2020
Rosamultin Attenuates Acute Hypobaric Hypoxia-Induced Bone Injuries by Regulation of Sclerostin and Its Downstream Signals.
High altitude medicine & biology
Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ
Tue Sep 01 00:00:00 EDT 2020
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Frontiers in neuroscience
Hongna Y,Hongzhao T,Quan L,Delin F,Guijun L,Xiaolin L,Fulin G,Zhongren S
Wed Feb 10 00:00:00 EST 2021
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
British journal of pharmacology
Huo X,Meng Q,Wang C,Wu J,Wang C,Zhu Y,Ma X,Sun H,Liu K
Fri May 01 00:00:00 EDT 2020
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Food & function
Wang J,Xu H,Cheng X,Yang J,Yan Z,Ma H,Zhao Y,Ommati MM,Manthari RK,Wang J
Wed Jan 29 00:00:00 EST 2020
Posttranslational lysine 2-hydroxyisobutyrylation of human sperm tail proteins affects motility.
Human reproduction (Oxford, England)
Cheng YM,Peng Z,Chen HY,Pan TT,Hu XN,Wang F,Luo T
Fri Mar 27 00:00:00 EDT 2020
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Brain research
Li Y,Wu J,Yu S,Zhu J,Zhou Y,Wang P,Li L,Zhao Y
Thu Oct 15 00:00:00 EDT 2020
Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene.
Journal of cellular and molecular medicine
Wang X,Xu X,Jiang G,Zhang C,Liu L,Kang J,Wang J,Owusu L,Zhou L,Zhang L,Li W
Thu Oct 01 00:00:00 EDT 2020
Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs.
Meat science
Cheng K,Yu C,Li Z,Li S,Yan E,Song Z,Zhang H,Zhang L,Wang T
Tue Dec 01 00:00:00 EST 2020
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
EMBO molecular medicine
Li SB,Liu YY,Yuan L,Ji MF,Zhang A,Li HY,Tang LQ,Fang SG,Zhang H,Xing S,Li MZ,Zhong Q,Lin SJ,Liu WL,Huang P,Zeng YX,Zheng YM,Ling ZQ,Sui JH,Zeng MS
Mon Sep 07 00:00:00 EDT 2020
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Frontiers in microbiology
Hu S,Li Z,Lan Y,Guan J,Zhao K,Chu D,Fan G,Guo Y,Gao F,He W
Mon Sep 28 00:00:00 EDT 2020
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Xu X,Zhang X,Wei C,Zheng D,Lu X,Yang Y,Luo A,Zhang K,Duan X,Wang Y
Tue Sep 01 00:00:00 EDT 2020
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Y,Chen Y,Li B,Ding P,Jin D,Hou S,Cai X,Sheng X
Tue Sep 01 00:00:00 EDT 2020
Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis.
Frontiers in cell and developmental biology
Wang G,Wu X,Zhou L,Gao S,Yun D,Liang A,Sun F
Tue Oct 06 00:00:00 EDT 2020
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy.
Journal of inorganic biochemistry
Liu Y,Zhao H,Wang Y,Guo M,Mu M,Xing M
Thu Oct 01 00:00:00 EDT 2020
Increased regulatory T cells and eosinophils characterize atopic dermatitis-like graft-versus-host disease compared with lichen planus-like graft-versus-host disease.
Journal of the American Academy of Dermatology
Li K,Mu Z,Wen G,Zhao Y,Cong X,Zhang J
Tue Sep 01 00:00:00 EDT 2020
FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.
European review for medical and pharmacological sciences
Yao F,Jiang DD,Guo WH,Guo LS,Gao MM,Bai Y,Wang X,Zhang LS
Tue Dec 01 00:00:00 EST 2020
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Journal of agricultural and food chemistry
Ren C,Wang Y,Lin X,Song H,Zhou Q,Xu W,Shi K,Chen J,Song J,Chen F,Zhang S,Guan W
Wed Apr 08 00:00:00 EDT 2020
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Neurochemical research
Liu XF,Tang CX,Zhang L,Tong SY,Wang Y,Abdulrahman AA,Ji GQ,Gao Y,Gao DS,Zhang BL
Tue Dec 01 00:00:00 EST 2020
Zinc exerts its renal protection effect on arsenic-exposed common carp: A signaling network comprising Nrf2, NF-κB and MAPK pathways.
Fish & shellfish immunology
Wang Y,Zhao H,Liu Y,Nie X,Xing M
Tue Sep 01 00:00:00 EDT 2020
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Experimental cell research
Wang Q,Ren H,Xu Y,Jiang J,Wudu M,Liu Z,Su H,Jiang X,Zhang Y,Zhang B,Qiu X
Sat Feb 15 00:00:00 EST 2020
Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
Journal of neurochemistry
Zhou X,Liang J,Wang J,Fei Z,Qin G,Zhang D,Zhou J,Chen L
Sun Nov 01 00:00:00 EDT 2020
Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ni D,Ai Z,Munoz-Sandoval D,Suresh R,Ellis PR,Yuqiong C,Sharp PA,Butterworth PJ,Yu Z,Corpe CP
Sat Aug 01 00:00:00 EDT 2020
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis.
Cancer research
Niu Y,Bao L,Chen Y,Wang C,Luo M,Zhang B,Zhou M,Wang JE,Fang YV,Kumar A,Xing C,Wang Y,Luo W
Sun Mar 01 00:00:00 EST 2020
Downregulation of miR-140-5p affects the pathogenesis of HSCR by targeting EGR2.
Pediatric surgery international
Du G,Wang X,Wu Y,Zhang Y,Liu W,Wu R
Sat Aug 01 00:00:00 EDT 2020
The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples.
Nutrients
Pinto AP,Vieira TS,Marafon BB,Batitucci G,Cabrera EMB,da Rocha AL,Kohama EB,Rodrigues KCC,de Moura LP,Pauli JR,Cintra DE,Ropelle ER,de Freitas EC,da Silva ASR
Fri Feb 28 00:00:00 EST 2020
Indirubin alleviates bleomycin-induced pulmonary fibrosis in mice by suppressing fibroblast to myofibroblast differentiation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang Q,Yu J,Hu Y,Chen X,Zhang L,Pan T,Miao K,Mou Y,Xu Y,Xiong W,Wang Y
Sun Nov 01 00:00:00 EDT 2020
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Yuan C,Yang D,Ma J,Yang J,Xue J,Song F,Liu X
Fri Aug 28 00:00:00 EDT 2020
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.
Nature communications
Atkinson N,Mao Y,Chan KX,McCormick AJ
Wed Dec 09 00:00:00 EST 2020
Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis.
Oncology letters
Tan S,Hou X,Mei L
Thu Oct 01 00:00:00 EDT 2020
Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5.
Connective tissue research
Sun HY,Yang D,Mi J,Yu YQ,Qiu LH
Sun Nov 01 00:00:00 EDT 2020
Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway.
Journal of physiology and biochemistry
Meng X,Ma J,Wang B,Wu X,Liu Z
Fri May 01 00:00:00 EDT 2020
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
International immunopharmacology
Tian M,Ma P,Zhang Y,Mi Y,Fan D
Sat Aug 01 00:00:00 EDT 2020
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Nature
Qian H,Kang X,Hu J,Zhang D,Liang Z,Meng F,Zhang X,Xue Y,Maimon R,Dowdy SF,Devaraj NK,Zhou Z,Mobley WC,Cleveland DW,Fu XD
Mon Jun 01 00:00:00 EDT 2020
Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.
Frontiers in immunology
Li R,Sun N,Chen X,Li X,Zhao J,Cheng W,Hua H,Fukatsu M,Mori H,Takahashi H,Ohkawara H,Fukami M,Okamoto M,Hamazaki Y,Zheng K,Yang J,Ikezoe T
Thu Jul 15 00:00:00 EDT 2021
Innate Effector Systems in Primary Human Macrophages Sensitize Multidrug-Resistant Klebsiella pneumoniae to Antibiotics.
Infection and immunity
Rekha RS,Karadottir H,Ahmed S,Gudmundsson GH,Agerberth B,Bergman P
Tue Jul 21 00:00:00 EDT 2020
NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese encephalitis virus genotype I over genotype III in ducklings.
PLoS pathogens
Li C,Di D,Huang H,Wang X,Xia Q,Ma X,Liu K,Li B,Shao D,Qiu Y,Li Z,Wei J,Ma Z
Tue Sep 01 00:00:00 EDT 2020
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Journal of cellular and molecular medicine
Lan Y,Yan R,Shan W,Chu J,Sun R,Wang R,Zhao Y,Wang Z,Zhang N,Yao J
Sat Aug 01 00:00:00 EDT 2020
Role of Zinc Sulphate in Immune Regulation in Artemisia annua Pollen-challenged P815 Mastocytoma Cells.
Immunological investigations
Yang FX,Hou L,Wen WL,Shen XL,Feng NY,Ma RX,Yin S
Sat Aug 01 00:00:00 EDT 2020
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.
Biology of reproduction
Feng X,Zhang Y,Zhang Y,Yang X,Man D,Lu L,Xu T,Liu Y,Yang C,Li H,Qi L,Su H,Zhou X,Xu Z
Tue Dec 01 00:00:00 EST 2020
Rosmarinic Acid Alleviates Inflammation, Apoptosis, and Oxidative Stress through Regulating miR-155-5p in a Mice Model of Parkinson's Disease.
ACS chemical neuroscience
Lv R,Du L,Zhou F,Yuan X,Liu X,Zhang L
Wed Oct 21 00:00:00 EDT 2020
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability.
Cell host & microbe
Tsai K,Jaguva Vasudevan AA,Martinez Campos C,Emery A,Swanstrom R,Cullen BR
Wed Aug 12 00:00:00 EDT 2020
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Anti-cancer drugs
Miao J,Hou N,Yang W,Jiang Q,Xue W,Wang X,Zhang H,Xiong X,Wang L,Zhao L,Huang C
Wed Jul 01 00:00:00 EDT 2020
Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice.
Theranostics
Zhang J,Zhu S,Jin P,Huang Y,Dai Q,Zhu Q,Wei P,Yang Z,Zhang L,Liu H,Xu G,Chen L,Gu E,Zhang Y,Wen L,Liu X
Tue Jun 01 00:00:00 EDT 2021
Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.
Neuroscience
Cao Y,Zhang H,Lu X,Wang J,Zhang X,Sun S,Bao Z,Tian W,Ning S,Wang L,Cui L
Tue Sep 15 00:00:00 EDT 2020
HEATR1 promotes proliferation in gastric cancer in vitro and in vivo.
Acta biochimica et biophysica Sinica
Zhao J,Zhu Y,Fu Q,Zhu Y,Zhao G
Tue Sep 08 00:00:00 EDT 2020
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Diabetes, metabolic syndrome and obesity : targets and therapy
Ndibalema AR,Kabuye D,Wen S,Li L,Li X,Fan Q
Fri Apr 15 00:00:00 EDT 2022
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Experimental cell research
Song S,Qiu D,Wang Y,Wei J,Wu H,Wu M,Wang S,Zhou X,Shi Y,Duan H
Sun Mar 15 00:00:00 EDT 2020
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Chemico-biological interactions
Bai Z,Liu X,Guan Q,Ding N,Wei Q,Tong B,Zhao M,Zhang W,Ma L
Sun Jan 05 00:00:00 EST 2020
A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.
Frontiers in aging neuroscience
Wang J,Yang C,Wang H,Li D,Li T,Sun Y,Zhao M,Ma J,Hua W,Yang Z
Thu Apr 14 00:00:00 EDT 2022
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats.
RSC advances
Guo S,Wang L,Chen D,Jiang B
Thu Jan 16 00:00:00 EST 2020
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
Chemico-biological interactions
Wang K,Wei H,Zhan J,Liang X,Zhang C,Liu Y,Xu G
Sat Jan 25 00:00:00 EST 2020
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors.
Journal of medicinal chemistry
Yu Y,Han Y,Zhang F,Gao Z,Zhu T,Dong S,Ma M
Thu Mar 26 00:00:00 EDT 2020
Discovery of a first-in-class EZH2 selective degrader.
Nature chemical biology
Ma A,Stratikopoulos E,Park KS,Wei J,Martin TC,Yang X,Schwarz M,Leshchenko V,Rialdi A,Dale B,Lagana A,Guccione E,Parekh S,Parsons R,Jin J
Sat Feb 01 00:00:00 EST 2020
Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma.
Cell biochemistry and function
Li S,Yang H,Li K,Fan G,Deng L,Xu C
Sat Aug 01 00:00:00 EDT 2020
Nobiletin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Promoting Autophagy via the AMPK Pathway.
Molecular neurobiology
Wang H,Guo Y,Qiao Y,Zhang J,Jiang P
Tue Dec 01 00:00:00 EST 2020
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
OncoTargets and therapy
Cui D,Wang K,Liu Y,Gao J,Cui J
Sun Apr 17 00:00:00 EDT 2022
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
The Journal of biological chemistry
Zheng M,Williams EP,Malireddi RKS,Karki R,Banoth B,Burton A,Webby R,Channappanavar R,Jonsson CB,Kanneganti TD
Fri Oct 09 00:00:00 EDT 2020
A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.
Frontiers in pharmacology
Pan B,Wang Y,Wu C,Jia J,Huang C,Fang S,Liu L
Sat Jan 30 00:00:00 EST 2021
Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts.
Molecular medicine reports
Tao L,Zhao S,Tao Z,Wen K,Zhou S,Da W,Zhu Y
Sat Aug 01 00:00:00 EDT 2020
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Oncology letters
Li A,Zhang N,Zhao Z,Chen Y,Zhang L
Sat Aug 01 00:00:00 EDT 2020
Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling.
Frontiers in molecular neuroscience
Sun C,Fu J,Qu Z,Jia L,Li D,Zhen J,Wang W
Tue Feb 16 00:00:00 EST 2021
Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity.
Aging
Verdura S,Cuyàs E,Cortada E,Brunet J,Lopez-Bonet E,Martin-Castillo B,Bosch-Barrera J,Encinar JA,Menendez JA
Sat Jan 04 00:00:00 EST 2020
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu X,Xia M,Wang J,Yu H,Chai J,Zhang Z,Sun Y,Su J,Sun L
Tue Sep 01 00:00:00 EDT 2020
REDD1 overexpression in oral squamous cell carcinoma may predict poor prognosis and correlates with high microvessel density.
Oncology letters
Feng Y,Song K,Shang W,Chen L,Wang C,Pang B,Wang N
Wed Jan 01 00:00:00 EST 2020
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
EMBO reports
Wang Y,Huang Y,Liu J,Zhang J,Xu M,You Z,Peng C,Gong Z,Liu W
Tue Jan 07 00:00:00 EST 2020
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Pharmacological research
Zhou J,Zhao Y,Li Z,Zhu M,Wang Z,Li Y,Xu T,Feng D,Zhang S,Tang F,Yao J
Thu Oct 01 00:00:00 EDT 2020
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Experimental biology and medicine (Maywood, N.J.)
Yang R,Jia Q,Li Y,Mehmood S
Sat Aug 01 00:00:00 EDT 2020
SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity.
Aging
Feng X,Wang Y,Chen W,Xu S,Li L,Geng Y,Shen A,Gao H,Zhang L,Liu S
Wed Mar 04 00:00:00 EST 2020
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Journal of neuroinflammation
Chen M,Yang LL,Hu ZW,Qin C,Zhou LQ,Duan YL,Bosco DB,Wu LJ,Zhan KB,Xu SB,Tian DS
Fri Nov 06 00:00:00 EST 2020
HOTAIR promotes paclitaxel resistance by regulating CHEK1 in ovarian cancer.
Cancer chemotherapy and pharmacology
Jiang J,Wang S,Wang Z,Cai J,Han L,Xie L,Han Q,Wang W,Zhang Y,He X,Yang C
Sat Aug 01 00:00:00 EDT 2020
IGFBP‑rP1‑silencing promotes hypoxia‑induced angiogenic potential of choroidal endothelial cells via the RAF/MEK/ERK signaling pathway.
Molecular medicine reports
Zhu S,Wang H,Zhang Z,Ma M,Zheng Z,Xu X,Sun T
Tue Dec 01 00:00:00 EST 2020
Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation.
Epilepsy & behavior : E&B
Ye Q,Zeng C,Luo C,Wu Y
Sat Feb 01 00:00:00 EST 2020
Programmable prodrug micelle with size-shrinkage and charge-reversal for chemotherapy-improved IDO immunotherapy.
Biomaterials
Dai L,Li X,Yao M,Niu P,Yuan X,Li K,Chen M,Fu Z,Duan X,Liu H,Cai K,Yang H
Fri May 01 00:00:00 EDT 2020
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
Neurochemistry international
Zhang S,Wang S,Shi X,Feng X
Thu Oct 01 00:00:00 EDT 2020
Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.
Carcinogenesis
Yang N,Ying P,Tian J,Wang X,Mei S,Zou D,Peng X,Gong Y,Yang Y,Zhu Y,Ke J,Zhong R,Chang J,Miao X
Fri Jul 10 00:00:00 EDT 2020
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer.
Cancer management and research
Chen X,Yu Q,Pan H,Li P,Wang X,Fu S
Sat Apr 16 00:00:00 EDT 2022
PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b.
Chemosphere
Li J,Quan XJ,Chen G,Hong JW,Wang Q,Xu LL,Wang BH,Yu ZH,Yu HM
Tue Dec 01 00:00:00 EST 2020
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Journal of Cancer
Zhu G,Li X,Li J,Zhou W,Chen Z,Fan Y,Jiang Y,Zhao Y,Sun G,Mao W
Fri Oct 16 00:00:00 EDT 2020
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Chen Z,Li Z,Hu X,Xie F,Kuang S,Zhan B,Gao W,Chen X,Gao S,Li Y,Wang Y,Qian F,Ding C,Gan J,Ji C,Xu XW,Zhou Z,Huang J,He HH,Li J
Wed Jul 01 00:00:00 EDT 2020
Enterovirus A71 Oncolysis of Malignant Gliomas.
Molecular therapy : the journal of the American Society of Gene Therapy
Zhang X,Wang H,Sun Y,Qi M,Li W,Zhang Z,Zhang XE,Cui Z
Wed Jun 03 00:00:00 EDT 2020
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
PPAR research
Xia Y,Li J,Chen K,Feng J,Guo C
Tue Jan 26 00:00:00 EST 2021
Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-β signalling by interacting with STAT1.
Veterinary research
He T,Wang M,Cheng A,Yang Q,Jia R,Wu Y,Huang J,Chen S,Zhao XX,Liu M,Zhu D,Zhang S,Ou X,Mao S,Gao Q,Sun D,Wen X,Tian B,Liu Y,Yu Y,Zhang L,Pan L,Chen X
Wed Nov 11 00:00:00 EST 2020
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Cell cycle (Georgetown, Tex.)
Liu D,Zhang H,Cui M,Chen C,Feng Y
Sat Aug 01 00:00:00 EDT 2020
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Theranostics
Zhang Y,Wang S,Zhang L,Zhou F,Zhu K,Zhu Q,Liu Q,Liu Y,Jiang L,Ning G,Bi Y,Zhou L,Wang X
Mon May 03 00:00:00 EDT 2021
TRIM24 promotes stemness and invasiveness of glioblastoma cells via activating Sox2 expression.
Neuro-oncology
Zhang LH,Yin YH,Chen HZ,Feng SY,Liu JL,Chen L,Fu WL,Sun GC,Yu XG,Xu DG
Fri Dec 18 00:00:00 EST 2020
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
PeerJ
Wu J,Li X,Huang H,Xia X,Zhang M,Fang X
Sun Apr 17 00:00:00 EDT 2022
Targeting HMGB3/hTERT axis for radioresistance in cervical cancer.
Journal of experimental & clinical cancer research : CR
Li Z,Zhang Y,Sui S,Hua Y,Zhao A,Tian X,Wang R,Guo W,Yu W,Zou K,Deng W,He L,Zou L
Fri Nov 13 00:00:00 EST 2020
α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells.
ACS omega
Li Q,Yan XT,Zhao LC,Ren S,He YF,Liu WC,Wang Z,Li XD,Jiang S,Li W
Tue Aug 18 00:00:00 EDT 2020
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
British journal of pharmacology
Sun R,Kang X,Zhao Y,Wang Z,Wang R,Fu R,Li Y,Hu Y,Wang Z,Shan W,Zhou J,Tian X,Yao J
Tue Sep 01 00:00:00 EDT 2020
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice.
Frontiers in pharmacology
Hu J,Zhu Z,Ying H,Yao J,Ma H,Li L,Zhao Y
Sat Feb 06 00:00:00 EST 2021
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
International immunopharmacology
Ma X,Guo Z,Zhang Z,Li X,Wang X,Liu Y,Wang X
Mon Jun 01 00:00:00 EDT 2020
STIM2 knockdown protects against ischemia/reperfusion injury through reducing mitochondrial calcium overload and preserving mitochondrial function.
Life sciences
Tu CC,Wan BY,Zeng Y
Wed Apr 15 00:00:00 EDT 2020
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Cell death discovery
Fang Y,Li F,Qi C,Mao X,Wang F,Zhao Z,Chen JK,Zhang Z,Wu H
Tue Sep 26 00:00:00 EDT 2023
Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo.
International immunopharmacology
Liu N,Ma M,Qu N,Wang R,Chen H,Hu F,Gao S,Shan F
Tue Sep 01 00:00:00 EDT 2020
ALKATI interacts with c-Myc and promotes cancer stem cell-like properties in sarcoma.
Oncogene
Xu BS,Chen HY,Que Y,Xiao W,Zeng MS,Zhang X
Wed Jan 01 00:00:00 EST 2020
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Journal of Alzheimer's disease : JAD
Huang Y,Huang W,Huang Y,Song P,Zhang M,Zhang HT,Pan S,Hu Y
Fri May 07 00:00:00 EDT 2021
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Cell death & disease
Bi Y,Guo S,Xu X,Kong P,Cui H,Yan T,Ma Y,Cheng Y,Chen Y,Liu X,Zhang L,Cheng C,Xu E,Qian Y,Yang J,Song B,Li H,Wang F,Hu X,Liu X,Niu X,Zhai Y,Liu J,Li Y,Cheng X,Cui Y
Mon Apr 27 00:00:00 EDT 2020
Role of ion channels in chronic intermittent hypoxia-induced atrial remodeling in rats.
Life sciences
Zhang K,Ma Z,Song C,Duan X,Yang Y,Li G
Sat Aug 01 00:00:00 EDT 2020
PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells.
Genes
Jiao P,Yuan Y,Zhang M,Sun Y,Wei C,Xie X,Zhang Y,Wang S,Chen Z,Wang X
Thu Feb 13 00:00:00 EST 2020
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Food & function
Chen Z,Xiao J,Liu H,Yao K,Hou X,Cao Y,Liu X
Wed Sep 23 00:00:00 EDT 2020
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Cancer science
Liu B,Xiao J,Dong M,Qiu Z,Jin J
Wed Jul 01 00:00:00 EDT 2020
Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria.
Diabetes, metabolic syndrome and obesity : targets and therapy
Ning J,Xiang Z,Xiong C,Zhou Q,Wang X,Zou H
Fri Apr 15 00:00:00 EDT 2022
Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.
Evidence-based complementary and alternative medicine : eCAM
Lin Y,Tang L,Huang P,Liu T,Zhong J,Xu Q,Li X,Lin Y,Xiao S,Cai J
Mon Sep 28 00:00:00 EDT 2020
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Toxicology in vitro : an international journal published in association with BIBRA
Yang YX,Yu S,Jia BX,Liu N,Wu A
Sat Aug 01 00:00:00 EDT 2020
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Cancer science
Yu YP,Cai LC,Wang XY,Cheng SY,Zhang DM,Jian WG,Wang TD,Yang JK,Yang KB,Zhang C
Fri May 01 00:00:00 EDT 2020
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
American journal of physiology. Heart and circulatory physiology
Liu H,Tang D,Zhou X,Yang X,Chen AF
Tue Dec 01 00:00:00 EST 2020
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
Experimental neurology
Liu X,Hu R,Pei L,Si P,Wang C,Tian X,Wang X,Liu H,Wang B,Xia Z,Xu Y,Song B
Mon Jun 01 00:00:00 EDT 2020
HMGB1-induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang C,Hu J,Wang W,Sun Y,Sun K
Wed Jul 01 00:00:00 EDT 2020
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Nature communications
Zuo Y,Feng Q,Jin L,Huang F,Miao Y,Liu J,Xu Y,Chen X,Zhang H,Guo T,Yuan Y,Zhang L,Wang J,Zheng H
Mon Mar 02 00:00:00 EST 2020
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells.
International journal of molecular sciences
Sakari M,Suzuki T,Yano S,Tsukahara T
Tue Nov 24 00:00:00 EST 2020
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
Toxicology and applied pharmacology
Jiang M,He J,Gu H,Yang Y,Huang Y,Xu X,Liu L
Sat Feb 01 00:00:00 EST 2020
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Neurotoxicity research
Yang GM,Li L,Xue FL,Ma CL,Zeng XF,Zhao YN,Zhang DX,Yu Y,Yan QW,Zhou YQ,Hong SJ,Li LH
Wed Apr 01 00:00:00 EDT 2020
RhoB is regulated by hypoxia and modulates metastasis in breast cancer.
Cancer reports (Hoboken, N.J.)
Ju JA,Godet I,DiGiacomo JW,Gilkes DM
Sat Feb 01 00:00:00 EST 2020
Adenovirus-mediated specific tumor tagging facilitates CAR-T therapy against antigen-mismatched solid tumors.
Cancer letters
Tang X,Li Y,Ma J,Wang X,Zhao W,Hossain MA,Yang Y
Tue Sep 01 00:00:00 EDT 2020
Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia.
Hypertension research : official journal of the Japanese Society of Hypertension
Wei LL,Pan YS,Tang Q,Yang ZJ,Song WQ,Gao YF,Li J,Zhang L,Liu SG
Wed Jan 01 00:00:00 EST 2020
TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neuron injury of Parkinson's disease.
Human molecular genetics
Wu TT,Liu T,Li X,Chen YJ,Chen TJ,Zhu XY,Chen JL,Li Q,Liu Y,Feng Y,Wu YC
Thu May 28 00:00:00 EDT 2020
Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.
Brain research bulletin
Jiang W,Wang X,Wang W,Hua F,Zhang Z,Zhang Z,Xiang J,Yang X
Tue Sep 01 00:00:00 EDT 2020
Quercetin suppresses migration and invasion by targeting miR-146a/GATA6 axis in fibroblast-like synoviocytes of rheumatoid arthritis.
Immunopharmacology and immunotoxicology
Zhao J,Chen B,Peng X,Wang C,Wang K,Han F,Xu J
Mon Jun 01 00:00:00 EDT 2020
Matrix Metalloproteinase 11 as a Novel Tumor Promoter and Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma.
Pancreas
Zhang X,Lu J,Zhou L,You L,Liang Z,Guo J,Zhao Y
Wed Jul 01 00:00:00 EDT 2020
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Toxicology in vitro : an international journal published in association with BIBRA
Liang LY,Wang MM,Liu M,Zhao W,Wang X,Shi L,Zhu MJ,Zhao YL,Liu L,Maurya P,Wang Y
Sat Feb 01 00:00:00 EST 2020
Retinoid X receptor α (RXRα)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells.
Journal of applied toxicology : JAT
Jiang H,Li R,Zhang Z,Chang C,Liu Y,Liu Z,He Q,Wang Q
Wed Apr 01 00:00:00 EDT 2020
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
Life sciences
Li Y,Li J,Hou Y,Huang L,Bian Y,Song G,Qiao C
Wed Apr 15 00:00:00 EDT 2020
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Oxidative medicine and cellular longevity
Wang W,Hu X,Xia Z,Liu Z,Zhong Z,Lu Z,Liu A,Ye S,Cao Q,Wang Y,Zhu F,Ye Q
Wed Dec 16 00:00:00 EST 2020
Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Liu A,Zuo Z,Liu L,Liu L
Thu Oct 01 00:00:00 EDT 2020
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Life sciences
Zhang C,Jia Y,Liu B,Wang G,Zhang Y
Sat Aug 01 00:00:00 EDT 2020
Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway.
International immunopharmacology
Xia M,Liu D,Tang X,Liu Y,Liu H,Liu Y,Chen G,Liu H
Sun Mar 01 00:00:00 EST 2020
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Cancer management and research
Luo W,Han Y,Meng P,Yang Q,Zhao H,Ling J,Wang Y
Tue Apr 19 00:00:00 EDT 2022
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Oncology letters
Niu W,Xu L,Li J,Zhai Y,Sun Z,Shi W,Jiang Y,Ma C,Lin H,Guo Y,Liu Z
Tue Sep 01 00:00:00 EDT 2020
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
BioFactors (Oxford, England)
Lin D,Cui B,Ma J,Ren J
Wed Jan 01 00:00:00 EST 2020
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Mediators of inflammation
Dong Y,Hong W,Tang Z,Gao Y,Wu X,Liu H
Mon Jun 21 00:00:00 EDT 2021
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
Molecular and cellular endocrinology
Su H,Qiao J,Hu J,Li Y,Lin J,Yu Q,Zhen J,Ma Q,Wang Q,Lv Z,Wang R
Tue Dec 01 00:00:00 EST 2020
Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells.
Aging
Wang F,Zhang L,Liu J,Zhang J,Xu G
Tue Jun 09 00:00:00 EDT 2020
α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
American journal of cancer research
Li F,Zhao S,Cui Y,Guo T,Qiang J,Xie Q,Yu W,Guo W,Deng W,Gu C,Wu T
Mon Sep 28 00:00:00 EDT 2020
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity.
Frontiers in pharmacology
Deng HF,Yue LX,Wang NN,Zhou YQ,Zhou W,Liu X,Ni YH,Huang CS,Qiu LZ,Liu H,Tan HL,Tang XL,Wang YG,Ma ZC,Gao Y
Tue Feb 16 00:00:00 EST 2021
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
International journal of biological macromolecules
Wu Z,Cheng Y,Yang Y,Gao Y,Sun X,Wang L,Sun Q,Zhang J,Xu X
Fri May 01 00:00:00 EDT 2020
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Journal of molecular medicine (Berlin, Germany)
Xiao H,Chen H,Jiang R,Zhang L,Wang L,Gan H,Jiang N,Zhao J,Zhai X,Liang P
Tue Sep 01 00:00:00 EDT 2020
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Journal of natural medicines
Li Y,Chen H,Yang Y,Niu M,Wang J,Wu Y,Niu L,Liu H,Bao D
Sun Mar 01 00:00:00 EST 2020
Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets.
Journal of cellular and molecular medicine
Jia N,Liu J,Zhu G,Liang Y,Wang Y,Wang W,Chen Y,Yang J,Zhang W,Zhang J
Tue Dec 01 00:00:00 EST 2020
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis.
BMC complementary medicine and therapies
Wang H,Zhu J,Jiang L,Shan B,Xiao P,Ai J,Li N,Qi F,Niu S
Thu Jun 11 00:00:00 EDT 2020
Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers.
OncoTargets and therapy
Zhao L,Zhang J,Qu X,Yang Y,Gong Z,Yang Y,Wu Z,Guo W
Thu Apr 14 00:00:00 EDT 2022
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Oncology research
Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H
Tue Sep 01 00:00:00 EDT 2020
PAQR3 protects against oxygen-glucose deprivation/reperfusion-induced injury through the ERK signaling pathway in N2A cells.
Journal of molecular histology
Peng W,Mo X,Li L,Lu T,Hu Z
Mon Jun 01 00:00:00 EDT 2020
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Anti-cancer drugs
Gong C,Hu X,Xu Y,Yang J,Zong L,Wang C,Zhu J,Li Z,Lu D
Sat Feb 01 00:00:00 EST 2020
Maternal Methyl-Donor Micronutrient Supplementation During Pregnancy Promotes Skeletal Muscle Differentiation and Maturity in Newborn and Weaning Pigs.
Frontiers in nutrition
He Q,Zou T,Chen J,Jian L,He J,Xia Y,Xie F,Wang Z,You J
Fri Dec 18 00:00:00 EST 2020
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
BioMed research international
Hu T,Zhang Q,Gao L
Mon Nov 02 00:00:00 EST 2020
Identification of octopus peptide and its promotion of β-casein synthesis in a mouse mammary epithelial cell line.
Journal of food biochemistry
Cai B,Wan P,Chen H,Chen X,Sun H,Pan J
Sun Nov 01 00:00:00 EDT 2020
Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients.
Molecular medicine reports
Liu Y,Zhao Y,Tang R,Jiang X,Wang Y,Gu T
Tue Dec 01 00:00:00 EST 2020
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Veterinary sciences
Zou YJ,Xu JJ,Wang X,Zhu YH,Wu Q,Wang JF
Fri Aug 14 00:00:00 EDT 2020
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Journal of experimental & clinical cancer research : CR
Liu JZ,Hu YL,Feng Y,Jiang Y,Guo YB,Liu YF,Chen X,Yang JL,Chen YY,Mao QS,Xue WJ
Tue Jun 30 00:00:00 EDT 2020
The roles of grouper TANK in innate immune defense against iridovirus and nodavirus infections.
Fish & shellfish immunology
Wei J,Li C,Ou J,Zhang X,Liu Z,Qin Q
Tue Sep 01 00:00:00 EDT 2020
Excessive Mg2+ Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Antioxidants & redox signaling
Hashizume O,Funato Y,Yamazaki D,Miki H
Wed Jul 01 00:00:00 EDT 2020
LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.
Human cell
Ma Q,Qi X,Lin X,Li L,Chen L,Hu W
Wed Jan 01 00:00:00 EST 2020
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Journal of hazardous materials
Liu H,Zhang W,Fang Y,Yang H,Tian L,Li K,Lai W,Bian L,Lin B,Liu X,Xi Z
Mon Jun 15 00:00:00 EDT 2020
Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF.
Cell death & disease
Li Y,Liu Z,Tang Y,Feng W,Zhao C,Liao J,Zhang C,Chen H,Ren Y,Dong S,Liu Y,Hu N,Huang W
Wed Jan 29 00:00:00 EST 2020
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Cancer medicine
Guo Y,Fan Y,Pei X
Wed Apr 01 00:00:00 EDT 2020
The knockdown of the sepiapterin reductase gene suppresses the proliferation of breast cancer by inducing ROS-mediated apoptosis.
International journal of clinical and experimental pathology
Zhang X,Chen Y,Wang K,Tang J,Chen Y,Jin G,Liu X
Tue Oct 13 00:00:00 EDT 2020
Oxidative stress is important in the pathogenesis of stress-related mucosal disease.
Experimental and therapeutic medicine
Wang X,Zhao Q,Shi H,Qi F,Shi N,Bai D,Li X,Yuan H,Zuo X
Sun Nov 01 00:00:00 EDT 2020
PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production.
Annals of translational medicine
Tan Y,Shao R,Li J,Huang H,Wang Y,Zhang M,Cao J,Zhang J,Bu J
Sat Feb 01 00:00:00 EST 2020
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Biochemical pharmacology
Liu X,Zhang Y,Wu S,Xu M,Shen Y,Yu M,Fan J,Wei S,Xu C,Huang L,Zhao H,Li X,Ye X
Fri May 01 00:00:00 EDT 2020
Lian Hua Qing Wen Capsules, a Potent Epithelial Protector in Acute Lung Injury Model, Block Proapoptotic Communication Between Macrophages, and Alveolar Epithelial Cells.
Frontiers in pharmacology
Li Q,Ran Q,Sun L,Yin J,Luo T,Liu L,Zhao Z,Yang Q,Li Y,Chen Y,Weng X,Wang Y,Cai W,Zhu X
Thu Oct 22 00:00:00 EDT 2020
Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats.
Oxidative medicine and cellular longevity
Lv WJ,Liu C,Yu LZ,Zhou JH,Li Y,Xiong Y,Guo A,Chao LM,Qu Q,Wei GW,Tang XG,Yin YL,Guo SN
Thu May 13 00:00:00 EDT 2021
Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease.
Stem cell research & therapy
Wang Y,Guo YF,Fu GP,Guan C,Zhang X,Yang DG,Shi YC
Wed Jul 08 00:00:00 EDT 2020
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wang Y,Chen Y,Zhang H,Chen J,Cao J,Chen Q,Li X,Sun C
Tue Dec 01 00:00:00 EST 2020
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair.
Theranostics
Wang L,Zhang F,Duan F,Huang R,Chen X,Ming J,Na J
Tue May 18 00:00:00 EDT 2021
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Redox biology
Wang Y,Chen J,Li S,Zhang X,Guo Z,Hu J,Shao X,Song N,Zhao Y,Li H,Yang G,Xu C,Wei C
Fri May 01 00:00:00 EDT 2020
MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α.
Clinical and experimental pharmacology & physiology
Han N,Xu H,Yu N,Wu Y,Yu L
Wed Jan 01 00:00:00 EST 2020
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Molecular medicine reports
Zhou X,Chen Q,Huang H,Zhang J,Wang J,Chen Y,Peng Y,Zhang H,Zeng J,Feng Z,Xu Z
Tue Dec 01 00:00:00 EST 2020
MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts.
Journal of bone and mineral metabolism
Cao X,Luo D,Li T,Huang Z,Zou W,Wang L,Lian K,Lin D
Wed Jan 01 00:00:00 EST 2020
Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer's disease.
PeerJ
Fang Y,Ou S,Wu T,Zhou L,Tang H,Jiang M,Xu J,Guo K
Fri Apr 15 00:00:00 EDT 2022
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Cell proliferation
Wang X,Liu M,Zhu MJ,Shi L,Liu L,Zhao YL,Cheng L,Gu YJ,Zhou MY,Chen L,Kumar A,Wang Y
Sun Mar 01 00:00:00 EST 2020
Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
Journal of investigative medicine high impact case reports
Moore JA,Hubbi ME,Wang C,Wang Y,Luo W,Hofmann S,Rambally S
Wed Aug 04 00:00:00 EDT 2021
Molecular identification, tissue distribution and in vitro functional analysis of growth hormone and its receptors in red-spotted grouper (Epinephelus akaara).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Yuan X,Lin Y,Qin J,Zhang Y,Yang G,Cai R,Liao Z,Sun C,Li W
Tue Dec 01 00:00:00 EST 2020
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Ecotoxicology and environmental safety
Li S,Shi M,Wan Y,Wang Y,Zhu M,Wang B,Zhan Y,Ran B,Wu C
Tue Sep 15 00:00:00 EDT 2020
S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity.
Virology
Xu Z,Li X,Xue J,Shen L,Zheng W,Yin S,Xu J
Tue Sep 01 00:00:00 EDT 2020
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Journal of experimental & clinical cancer research : CR
Sun Z,Zhang Q,Yuan W,Li X,Chen C,Guo Y,Shao B,Dang Q,Zhou Q,Wang Q,Wang G,Liu J,Kan Q
Fri Nov 20 00:00:00 EST 2020
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
Frontiers in oncology
Liu R,Wu Z,Zhang Y,Miao X,Zou Q,Yuan Y,Li D,Yang Z
Mon Sep 28 00:00:00 EDT 2020
Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice.
Microorganisms
Wang J,Liu T,Mahmmod YS,Yang Z,Tan J,Ren Z,Zhang X,Yang X,Zhang XX,Yuan ZG
Tue Jul 28 00:00:00 EDT 2020
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Ecotoxicology and environmental safety
Li K,Huang M,Xu P,Wang M,Ye S,Wang Q,Zeng S,Chen X,Gao W,Chen J,Zhang Q,Zhong Z,Sun Y,Liu Q
Sun Mar 01 00:00:00 EST 2020
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells.
Ecotoxicology and environmental safety
Li K,Huang M,Xu P,Wang M,Ye S,Wang Q,Zeng S,Chen X,Gao W,Chen J,Zhang Q,Zhong Z,Sun Y,Liu Q
Sun Mar 01 00:00:00 EST 2020
TRIM25 upregulation by Mycobacterium tuberculosis infection promotes intracellular survival of M.tb in RAW264.7 cells.
Microbial pathogenesis
Liu H,Zhu T,Li Q,Xiong X,Wang J,Zhu X,Zhou X,Zhang L,Zhu Y,Peng Y,Chen Y,Hu C,Chen H,Guo A
Sun Nov 01 00:00:00 EDT 2020
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2.
Viruses
Wang Q,Fu S,Zhang J,Yuan Q,Li J,Xia N,Wen YM,Wang Y,Tong S
Tue Sep 01 00:00:00 EDT 2020
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Oxidative medicine and cellular longevity
Qi J,Chen X,Wu Q,Wang J,Zhang H,Mao A,Zhu M,Miao C
Tue Nov 17 00:00:00 EST 2020
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Brain sciences
Morgan SE,Schroten H,Ishikawa H,Zhao N
Sat Aug 08 00:00:00 EDT 2020
Up-regulation of L Antigen Family Member 3 Associates With Aggressive Progression of Breast Cancer.
Frontiers in oncology
Dong X,Lv S,Gu D,Zhang X,Ye Z
Wed Feb 10 00:00:00 EST 2021
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Aging
Zhou F,Xiong X,Li S,Liang J,Zhang X,Tian M,Li X,Gao M,Tang L,Li Y
Wed Jun 24 00:00:00 EDT 2020
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Journal of bacteriology
Luo H,Wu X,Xu Z,Hao X,Wang Y,Li M
Wed Sep 23 00:00:00 EDT 2020
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Biological trace element research
Yang X,Zhao H,Wang Y,Liu J,Guo M,Fei D,Mu M,Xing M
Mon Jun 01 00:00:00 EDT 2020
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1+T cells.
Cellular immunology
Zhuoya W,Nannan Z,Aiping Z,Guoyan W,Menghua D,Jiashen Z,Yanlian X,Xiying L
Mon Jun 01 00:00:00 EDT 2020
Effects of Starvation on Antioxidant-Related Signaling Molecules, Oxidative Stress, and Autophagy in Juvenile Chinese Perch Skeletal Muscle.
Marine biotechnology (New York, N.Y.)
Wu P,Wang A,Cheng J,Chen L,Pan Y,Li H,Zhang Q,Zhang J,Chu W,Zhang J
Sat Feb 01 00:00:00 EST 2020
SRSF10 inhibits the polymerase activity and replication of avian influenza virus by regulating the alternative splicing of chicken ANP32A.
Virus research
Fang A,Bi Z,Ye H,Yan L
Tue Sep 01 00:00:00 EDT 2020
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms.
ACS omega
Zhang C,Tan Y,Feng J,Huang C,Liu B,Fan Z,Xu B,Lu T
Tue Dec 08 00:00:00 EST 2020
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Frontiers in molecular neuroscience
Xu L,Zheng YL,Yin X,Xu SJ,Tian D,Zhang CY,Wang S,Ma JZ
Mon Sep 28 00:00:00 EDT 2020
Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic-induced DNA damage and repair in normal human liver cells.
Journal of applied toxicology : JAT
Zhang AL,Tang SF,Yang Y,Li CZ,Ding XJ,Zhao H,Wang JH,Yang GH,Li J
Tue Dec 01 00:00:00 EST 2020
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Frontiers in oncology
Tang H,Zheng J,Bai X,Yue KL,Liang JH,Li DY,Wang LP,Wang JL,Guo Q
Fri Dec 18 00:00:00 EST 2020
ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain.
Frontiers in endocrinology
Honda SI,Harada N
Fri May 28 00:00:00 EDT 2021
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
BioMed research international
Guo LP,Liu SX,Yang Q,Liu HY,Xu LL,Hao YH,Zhang XQ
Thu Jul 09 00:00:00 EDT 2020
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Cell stress & chaperones
Shi L,Liu BY,Wang X,Zhu MJ,Chen L,Zhou MY,Gu YJ,Cheng L,Wang Y
Tue Sep 01 00:00:00 EDT 2020
SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection.
Molecular immunology
Li L,Wu H,Li Q,Chen J,Xu K,Xu J,Su X
Tue Sep 01 00:00:00 EDT 2020
Angiopoietin-like protein 4 promotes very-low-density lipoprotein assembly and secretion in bovine hepatocytes in vitro.
IUBMB life
Kong Y,Zhao C,Huang Y,Liu Y,Liu S,Guo Y,Li M,Xu T,Zhao B,Wang J
Tue Dec 01 00:00:00 EST 2020
Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.
Oncology reports
Tang X,Li Y,Liu L,Guo R,Zhang P,Zhang Y,Zhang Y,Zhao J,Su J,Sun L,Liu Y
Sat Feb 01 00:00:00 EST 2020
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
Food & function
Xu W,Lin L,Liu A,Zhang T,Zhang S,Li Y,Chen J,Gong Z,Liu Z,Xiao W
Wed Sep 23 00:00:00 EDT 2020
ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer.
International journal of cancer
Liu ZH,Chen ML,Zhang Q,Zhang Y,An X,Luo YL,Liu XM,Liu SX,Liu Q,Yang T,Liu YM,Liu BL,Zhou AJ,Li MZ,Liu YJ,Liu ZX,Zhong Q
Wed Jul 15 00:00:00 EDT 2020
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Chemistry (Weinheim an der Bergstrasse, Germany)
Bian M,Sun Y,Liu Y,Xu Z,Fan R,Liu Z,Liu W
Tue Jun 02 00:00:00 EDT 2020
Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
Experimental and therapeutic medicine
Yu G,Sun X,Li L,Huang L,Liu H,Wang S,Ren Z,Zhang Y
Sun Mar 01 00:00:00 EST 2020
β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.
Aging
Zou K,Li Z,Zhang Y,Mu L,Chen M,Wang R,Deng W,Zou L,Liu J
Wed Dec 09 00:00:00 EST 2020
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
Journal of hepatology
Dai W,Xu L,Yu X,Zhang G,Guo H,Liu H,Song G,Weng S,Dong L,Zhu J,Liu T,Guo C,Shen X
Fri May 01 00:00:00 EDT 2020
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
Journal of cellular and molecular medicine
Chen Y,Cao W,Wang L,Zhong T
Wed Jul 01 00:00:00 EDT 2020
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Cellular and molecular life sciences : CMLS
Qi Q,Wang Y,Wang X,Yang J,Xie Y,Zhou J,Li X,Wang B
Mon Jun 01 00:00:00 EDT 2020
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Behavioural brain research
Liu Q,Guo X,Huang Z,He Q,Zhu D,Zhang S,Peng Z,Che Y,Feng X
Mon Apr 06 00:00:00 EDT 2020
Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer.
Frontiers in oncology
Wei R,Zhong S,Qiao L,Guo M,Shao M,Wang S,Jiang B,Yang Y,Gu C
Thu Oct 01 00:00:00 EDT 2020
Synergistic Neuroprotective Effect of Endogenously-Produced Hydroxytyrosol and Synaptic Vesicle Proteins on Pheochromocytoma Cell Line Against Salsolinol.
Molecules (Basel, Switzerland)
Manzoor R,Rasool A,Ahmed M,Kaleem U,Duru LN,Ma H,Deng Y
Wed Apr 08 00:00:00 EDT 2020
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Frontiers in neuroscience
Ji Y,Li Y,Zhao Z,Li P,Xie Y
Tue Apr 19 00:00:00 EDT 2022
Comparative analysis of two brine shrimps revealed differential expression pattern and functional characterization of CK2α under bacterial stimulation from different geographical distribution.
Fish & shellfish immunology
Wang Z,Hou Q,Wan K,Zhang R,Dong L,Zhang D,Yin H
Wed Apr 01 00:00:00 EDT 2020
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Molecular neurobiology
Yan C,Ma Z,Ma H,Li Q,Zhai Q,Jiang T,Zhang Z,Wang Q
Tue Sep 01 00:00:00 EDT 2020
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
ACS chemical neuroscience
Le K,Wu S,Chibaatar E,Ali AI,Guo Y
Wed Mar 18 00:00:00 EDT 2020
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xu S,Wang Y,Yu M,Wang D,Liang Y,Chen Y,Liao C,Xie Z,Zhao B,Han J,Duan Y,Yang X
Sun Mar 01 00:00:00 EST 2020
Histone Deacetylase SIRT1 Mediates C5b-9-Induced Cell Cycle in Oligodendrocytes.
Frontiers in immunology
Tatomir A,Rao G,Boodhoo D,Vlaicu SI,Beltrand A,Anselmo F,Rus V,Rus H
Thu Mar 25 00:00:00 EDT 2021
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
bioRxiv : the preprint server for biology
Karki R,Sharma BR,Tuladhar S,Williams EP,Zalduondo L,Samir P,Zheng M,Sundaram B,Banoth B,Malireddi RKS,Schreiner P,Neale G,Vogel P,Webby R,Jonsson CB,Kanneganti TD
Fri Nov 13 00:00:00 EST 2020
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Life science alliance
Rusilowicz-Jones EV,Jardine J,Kallinos A,Pinto-Fernandez A,Guenther F,Giurrandino M,Barone FG,McCarron K,Burke CJ,Murad A,Martinez A,Marcassa E,Gersch M,Buckmelter AJ,Kayser-Bricker KJ,Lamoliatte F,Gajbhiye A,Davis S,Scott HC,Murphy E,England K,Mortiboys H,Komander D,Trost M,Kessler BM,Ioannidis S,Ahlijanian MK,Urbé S,Clague MJ
Sat Aug 01 00:00:00 EDT 2020
Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells.
Toxins
Han N,Luo R,Liu J,Guo T,Feng J,Peng X
Thu Oct 29 00:00:00 EDT 2020
Esculetin Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Via Modulation of the AKT/ERK/NF-κB and RORγt/IL-17 Pathways.
Inflammation
Lee HC,Liu FC,Tsai CN,Chou AH,Liao CC,Yu HP
Mon Jun 01 00:00:00 EDT 2020
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Frontiers in pharmacology
Wang W,Long H,Huang W,Zhang T,Xie L,Chen C,Liu J,Xiong D,Hu W
Tue Dec 22 00:00:00 EST 2020
Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.
Frontiers in immunology
Liu Y,Xie P,Jiang D,Liu J,Zhang J,Bian T,Shi J
Thu May 13 00:00:00 EDT 2021
Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells.
European journal of pharmacology
Xu W,Wang X,Chen S,Wu H,Tanaka S,Onda K,Sugiyama K,Yamada H,Hirano T
Sat Aug 15 00:00:00 EDT 2020
Transcription factor RUNX2 regulates epithelial‑mesenchymal transition and progression in renal cell carcinomas.
Oncology reports
Liu B,Liu J,Yu H,Wang C,Kong C
Sat Feb 01 00:00:00 EST 2020
Duck IFIT5 differentially regulates Tembusu virus replication and inhibits virus-triggered innate immune response.
Cytokine
Wu X,Liu K,Jia R,Pan Y,Wang M,Chen S,Liu M,Zhu D,Zhao X,Wu Y,Yang Q,Zhang S,Huang J,Zhang L,Liu Y,Tian B,Pan L,Yu Y,Ur Rehman M,Yin Z,Jing B,Cheng A
Tue Sep 01 00:00:00 EDT 2020
Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition.
Pathology, research and practice
Zhang D,Wu P,Zhang Z,An W,Zhang C,Pan S,Tan Y,Xu H
Sat Aug 01 00:00:00 EDT 2020
Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer.
Oncology reports
Ding Y,Ma M,Li Q,Gao S,Li S,Liu J,Geng C
Mon Jun 01 00:00:00 EDT 2020
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
BMC complementary medicine and therapies
Chen JX,Li HY,Li TT,Fu WC,Du X,Liu CH,Zhang W
Wed Jan 29 00:00:00 EST 2020
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Evidence-based complementary and alternative medicine : eCAM
Zheng P,Tian X,Zhang W,Yang Z,Zhou J,Zheng J,Cui H,Tang T,Luo J,Wang Y
Mon Sep 28 00:00:00 EDT 2020
Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells.
Theranostics
Gao L,Mei S,Zhang S,Qin Q,Li H,Liao Y,Fan H,Liu Z,Zhu H
Thu Apr 08 00:00:00 EDT 2021
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress.
The Journal of endocrinology
Ma X,Gao F,Chen Q,Xuan X,Wang Y,Deng H,Yang F,Yuan L
Tue Sep 01 00:00:00 EDT 2020
Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.
Aging and disease
Guo YT,Lu Y,Jia YY,Qu HN,Qi D,Wang XQ,Song PY,Jin XS,Xu WH,Dong Y,Liang YY,Quan CS
Sat Feb 01 00:00:00 EST 2020
FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.
Biochemical and biophysical research communications
Yao X,Liu D,Zhou L,Xie Y,Li Y
Wed Jan 22 00:00:00 EST 2020
Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production.
BMC musculoskeletal disorders
Zhou L,Song H,Zhang Y,Ren Z,Li M,Fu Q
Wed Feb 19 00:00:00 EST 2020
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Medical science monitor : international medical journal of experimental and clinical research
Li JM,Yang F,Li J,Yuan WQ,Wang H,Luo YQ
Fri Aug 07 00:00:00 EDT 2020
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α.
Veterinary microbiology
Xu S,Chen D,Chen D,Hu Q,Zhou L,Ge X,Han J,Guo X,Yang H
Sat Aug 01 00:00:00 EDT 2020
Annexin A3 upregulates the infiltrated neutrophil-lymphocyte ratio to remodel the immune microenvironment in hepatocellular carcinoma.
International immunopharmacology
Zhu Q,Pan QZ,Zhong AL,Hu H,Zhao JJ,Tang Y,Hu WM,Li M,Weng DS,Chen MY,Ma G,Xia JC
Tue Dec 01 00:00:00 EST 2020
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Molecular medicine reports
Zhou S,Yang J,Wang M,Zheng D,Liu Y
Wed Jan 01 00:00:00 EST 2020
Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice.
Journal of cellular and molecular medicine
Qiu F,Han Y,Shao X,Paulo P,Li W,Zhu M,Tang N,Guo S,Chen Y,Wu H,Zhao D,Liu Y,Chu W
Tue Sep 01 00:00:00 EDT 2020
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
OncoTargets and therapy
Huang G,Chen J,Liu J,Zhang X,Duan H,Fang Q
Sun Apr 17 00:00:00 EDT 2022
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Drug design, development and therapy
Yu M,Peng L,Liu P,Yang M,Zhou H,Ding Y,Wang J,Huang W,Tan Q,Wang Y,Xie W,Kong H,Wang H
Mon Feb 08 00:00:00 EST 2021
TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
Journal of ethnopharmacology
Zhou D,Liu J,Hang Y,Li T,Li P,Guo S,Liu T,Xia Z,Wang Y
Mon Aug 10 00:00:00 EDT 2020
LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1.
Journal of cellular and molecular medicine
Li Y,Yan G,Zhang J,Chen W,Ding T,Yin Y,Li M,Zhu Y,Sun S,Yuan JH,Guo Z
Wed Jan 01 00:00:00 EST 2020
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Scientific reports
Harmouch E,Seitlinger J,Chaddad H,Ubeaud-Sequier G,Barths J,Saidu S,Désaubry L,Grandemange S,Massfelder T,Fuhrmann G,Fioretti F,Dontenwill M,Benkirane-Jessel N,Idoux-Gillet Y
Thu Aug 13 00:00:00 EDT 2020
Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Wang J,Zuo Y,Zhuang K,Luo K,Yan X,Li J,Zhang JH,Liu F
Sun Mar 01 00:00:00 EST 2020
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang D,Sun M,Zhang Y,Chen Z,Zang S,Li G,Li G,Clark AR,Huang J,Si L
Sun Nov 01 00:00:00 EDT 2020
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Journal of cellular physiology
Zhang X,Dang Y,Liu R,Zhao S,Ma J,Qin Y
Sun Nov 01 00:00:00 EDT 2020
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
Biochemistry. Biokhimiia
Chao R,Li D,Yue Z,Huang C,Kou Y,Zhou Q,Gao Y,Hasegawa T,Guo J,Li M
Sun Mar 01 00:00:00 EST 2020
Virus analog decreases estradiol secretion in FSH-treated human ovarian granulosa cells.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Fang Y,Wang B,Lyu S,Zhang K,Cheng Q,Zhu Y
Wed Apr 01 00:00:00 EDT 2020
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
Biochemical and biophysical research communications
Su W,Shi J,Zhao Y,Yan F,Lei L,Li H
Wed Jan 29 00:00:00 EST 2020
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Environmental pollution (Barking, Essex : 1987)
Liu J,Li X,Zhou G,Sang Y,Zhang Y,Zhao Y,Ge W,Sun Z,Zhou X
Thu Oct 01 00:00:00 EDT 2020
Environmental Pollutant Benzo[a]pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast.
BioMed research international
Ye Y,Jiang S,Zhang C,Cheng Y,Zhong H,Du T,Xu W,Azziz R,Zhang H,Zhao X
Wed May 05 00:00:00 EDT 2021
The Potential Effects of Aliskiren on Atrial Remodeling Induced by Chronic Intermittent Hypoxia in Rats.
Drug design, development and therapy
Miao S,Yang Y,Li R,Yin L,Zhang K,Cheng L,Xu X,Wang W,Zhao Z,Li G
Wed Jul 07 00:00:00 EDT 2021
Osthole inhibits cell proliferation by regulating the TGF-β1/Smad/p38 signaling pathways in pulmonary arterial smooth muscle cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yue Y,Li YQ,Fu S,Wu YT,Zhu L,Hua L,Lv JY,Li YL,Yang DL
Wed Jan 01 00:00:00 EST 2020
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
Journal of cellular and molecular medicine
Sun K,Wang X,Fang N,Xu A,Lin Y,Zhao X,Nazarali AJ,Ji S
Wed Jul 01 00:00:00 EDT 2020
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Cancer letters
Guo SS,Liu R,Wen YF,Liu LT,Yuan L,Li YX,Li Y,Hao WW,Peng JY,Chen DN,Tang QN,Sun XS,Guo L,Mo HY,Qian CN,Zeng MS,Bei JX,Sun SY,Chen QY,Tang LQ,Mai HQ
Wed Jan 01 00:00:00 EST 2020
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Canadian journal of physiology and pharmacology
Wang T,Zhu H,Hou Y,Duan W,Meng F,Liu Y
Sun Mar 01 00:00:00 EST 2020
The SCFβ-TrCP E3 Ubiquitin Ligase Regulates Immune Receptor Signaling by Targeting the Negative Regulatory Protein TIPE2.
Journal of immunology (Baltimore, Md. : 1950)
Lou Y,Han M,Song Y,Zhong J,Zhang W,Chen YH,Wang H
Wed Apr 15 00:00:00 EDT 2020
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Cell stress & chaperones
Huang L,Wang Y,Bai J,Yang Y,Wang F,Feng Y,Zhang R,Li F,Zhang P,Lv N,Lei L,Hu J,He A
Sun Mar 01 00:00:00 EST 2020
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Journal of neuroinflammation
Chang Y,Zhu J,Wang D,Li H,He Y,Liu K,Wang X,Peng Y,Pan S,Huang K
Thu Jul 23 00:00:00 EDT 2020
Targeting BCL10 by small peptides for the treatment of B cell lymphoma.
Theranostics
Bao W,Sun C,Sun X,He M,Yu H,Yan W,Wen F,Zhang L,Yang C
Tue Jun 01 00:00:00 EDT 2021
Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization.
Theranostics
Zong X,Li Y,Liu C,Qi W,Han D,Tucker L,Dong Y,Hu S,Yan X,Zhang Q
Mon May 31 00:00:00 EDT 2021
MicroRNA-34a Inhibition Alleviates Lung Injury in Cecal Ligation and Puncture Induced Septic Mice.
Frontiers in immunology
Chen S,Ding R,Hu Z,Yin X,Xiao F,Zhang W,Yan S,Lv C
Mon Apr 12 00:00:00 EDT 2021
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Journal of Cancer
Deng X,Wang Q,Cheng M,Chen Y,Yan X,Guo R,Sun L,Li Y,Liu Y
Wed Sep 30 00:00:00 EDT 2020
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Cancers
Blanas A,Zaal A,van der Haar Àvila I,Kempers M,Kruijssen L,de Kok M,Popovic MA,van der Horst JC,J van Vliet S
Thu Sep 10 00:00:00 EDT 2020
Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression.
Frontiers in cellular neuroscience
Liu J,Huang Y,He J,Zhuo Y,Chen W,Ge L,Duan D,Lu M,Hu Z
Tue Dec 08 00:00:00 EST 2020
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
Journal of cellular and molecular medicine
Hu C,Xia H,Bai S,Zhao J,Edwards H,Li X,Yang Y,Lyu J,Wang G,Zhan Y,Dong Y,Ge Y
Wed Jul 01 00:00:00 EDT 2020
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Environmental science and pollution research international
Wang J,Zhu H,Wang K,Yang Z,Liu Z
Wed Jul 01 00:00:00 EDT 2020
Setosphapyrone C and D accelerate macrophages cholesterol efflux by promoting LXRα/ABCA1 pathway.
Archives of pharmacal research
Li T,Yin J,Ji Y,Lin P,Li Y,Yang Z,Hu S,Wang J,Zhang B,Koshti S,Wang J,Ji C,Guo S
Sat Aug 01 00:00:00 EDT 2020
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
Proceedings of the National Academy of Sciences of the United States of America
He Z,An S,Chen J,Zhang S,Tan C,Yu J,Ye H,Wu Y,Yuan J,Wu J,Zhu X,Li M
Tue Sep 22 00:00:00 EDT 2020
RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.
Medical science monitor : international medical journal of experimental and clinical research
Wu X,Wang Y,Zhong W,Cheng H,Tian Z
Sun Feb 23 00:00:00 EST 2020
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Cell death and differentiation
Zhang J,Liu S,Li Q,Shi Y,Wu Y,Liu F,Wang S,Zaky MY,Yousuf W,Sun Q,Guo D,Wang T,Zhang Y,Wang Y,Li M,Liu H
Tue Sep 01 00:00:00 EDT 2020
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
International immunopharmacology
Zhu JJ,Yu BY,Fu CC,He MZ,Zhu JH,Chen BW,Zheng YH,Chen SQ,Fu XQ,Li PJ,Lin ZL
Tue Dec 01 00:00:00 EST 2020
All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice.
Molecular neurobiology
Zhu Y,Liu Y,Yang F,Chen W,Jiang J,He P,Jiang S,Li M,Xu R
Sat Aug 01 00:00:00 EDT 2020
PKM2-c-Myc-Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.
Frontiers in pharmacology
Yu P,Li AX,Chen XS,Tian M,Wang HY,Wang XL,Zhang Y,Wang KS,Cheng Y
Tue Oct 06 00:00:00 EDT 2020
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Antioxidants (Basel, Switzerland)
Sun B,Wang X,Liu X,Wang L,Ren F,Wang X,Leng X
Tue Aug 25 00:00:00 EDT 2020
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Biochemical pharmacology
Feng Q,Li X,Sun W,Sun M,Li Z,Sheng H,Xie F,Zhang S,Shan C
Sat Aug 01 00:00:00 EDT 2020
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
Biochimica et biophysica acta. Molecular cell research
Tang K,Li S,Li P,Xia Q,Yang R,Li T,Li L,Jiang Y,Qin X,Yang H,Wu C,You F,Tan Y,Liu Y
Fri May 01 00:00:00 EDT 2020
HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-κB Pathway.
BioMed research international
Xiao K,Yang L,Gao X,An Y,Xie W,Jingquan G
Wed Apr 28 00:00:00 EDT 2021
Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Le K,Song Z,Deng J,Peng X,Zhang J,Wang L,Zhou L,Bi H,Liao Z,Feng Z
Tue Dec 01 00:00:00 EST 2020
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model.
Neuroscience letters
Sun C,Jia G,Wang X,Wang Y,Liu Y
Sun Nov 01 00:00:00 EDT 2020
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Metabolism: clinical and experimental
Tian L,Xiao H,Li M,Wu X,Xie Y,Zhou J,Zhang X,Wang B
Wed Apr 01 00:00:00 EDT 2020
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis.
Molecular therapy. Nucleic acids
Yang R,Chen J,Xu B,Yang B,Fu J,Xiao S,Tan C,Chen H,Wang X
Fri Dec 04 00:00:00 EST 2020
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.
Viruses
Su W,Huang S,Zhu H,Zhang B,Wu X
Wed Apr 08 00:00:00 EDT 2020
Presynaptic Caytaxin prevents apoptosis via deactivating DAPK1 in the acute phase of cerebral ischemic stroke.
Experimental neurology
Wang S,Chen K,Yu J,Wang X,Li Q,Lv F,Shen H,Pei L
Wed Jul 01 00:00:00 EDT 2020
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Biochemical pharmacology
Zhou Y,Fu X,Guan Y,Gong M,He K,Huang B
Sat Feb 01 00:00:00 EST 2020
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Journal of molecular histology
Hu Q,Lan J,Liang W,Chen Y,Chen B,Liu Z,Xiong Y,Zhong Z,Wang Y,Ye Q
Tue Dec 01 00:00:00 EST 2020
WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility.
PLoS genetics
Kabrawala S,Zimmer MD,Campellone KG
Sun Mar 01 00:00:00 EST 2020
The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model.
Gene therapy
Duan W,Guo M,Yi L,Liu Y,Li Z,Ma Y,Zhang G,Liu Y,Bu H,Song X,Li C
Wed Apr 01 00:00:00 EDT 2020
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1.
Journal of cellular and molecular medicine
Zhang D,Fan R,Lei L,Lei L,Wang Y,Lv N,Chen P,Williamson RA,Wang B,Hu J
Sat Aug 01 00:00:00 EDT 2020
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
Biochemical and biophysical research communications
Huang W,Dong S,Cha Y,Yuan X
Sun Jul 05 00:00:00 EDT 2020
Profiling pro-neural to mesenchymal transition identifies a lncRNA signature in glioma.
Journal of translational medicine
Liang Q,Guan G,Li X,Wei C,Wu J,Cheng P,Wu A,Cheng W
Wed Oct 07 00:00:00 EDT 2020
Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males.
Aging
Ma J,Chen Q,Wang S,Ma R,Jing J,Yang Y,Feng Y,Zou Z,Zhang Y,Ge X,Xue T,Liang K,Cao S,Wang D,Chen L,Yao B
Thu May 07 00:00:00 EDT 2020
Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling.
Nutrients
Miyazaki N,Katsura R,Hamada K,Suzutani T
Fri May 01 00:00:00 EDT 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 EDT 2020
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE-/- mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Particle and fibre toxicology
Ma R,Qi Y,Zhao X,Li X,Sun X,Niu P,Li Y,Guo C,Chen R,Sun Z
Fri Oct 02 00:00:00 EDT 2020
Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis.
Evidence-based complementary and alternative medicine : eCAM
Zhang L,Liu J,Lin S,Tan J,Huang B,Lin J
Mon Sep 28 00:00:00 EDT 2020
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.
Cellular & molecular immunology
Lou Y,Han M,Liu H,Niu Y,Liang Y,Guo J,Zhang W,Wang H
Thu Oct 01 00:00:00 EDT 2020
Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation.
Frontiers in pharmacology
Ni J,Zhao Y,Su J,Liu Z,Fang S,Li L,Deng J,Fan G
Mon Sep 28 00:00:00 EDT 2020
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression.
Frontiers in cell and developmental biology
Liu HJ,Hu HM,Li GZ,Zhang Y,Wu F,Liu X,Wang KY,Zhang CB,Jiang T
Mon Sep 28 00:00:00 EDT 2020
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Neuromolecular medicine
Dana H,Bayramov KK,Delibaşı N,Tahtasakal R,Bayramov R,Hamurcu Z,Sener EF
Mon Jun 01 00:00:00 EDT 2020
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Clinics (Sao Paulo, Brazil)
Zhou X,Liu J,Yang S,Su Y,Meng Z,Hu Y
Thu Oct 15 00:00:00 EDT 2020
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
Stem cells (Dayton, Ohio)
Xie Y,Wang X,Wu X,Tian L,Zhou J,Li X,Wang B
Sun Mar 01 00:00:00 EST 2020
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model.
American journal of physiology. Endocrinology and metabolism
Ma X,Zhou Y,Qiao B,Jiang S,Shen Q,Han Y,Liu A,Chen X,Wei L,Zhou L,Zhao J
Fri May 01 00:00:00 EDT 2020
A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.
Urology
Bao X,Huang Y,Lyu Y,Xi Z,Xie H,Fu Q,Song L,Chen F
Thu Oct 01 00:00:00 EDT 2020
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Cytokine
Yang K,Zhan L,Lu T,Zhou C,Chen X,Dong Y,Lv G,Chen S
Thu Mar 26 00:00:00 EDT 2020
Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Nabeel AI
Sun Mar 01 00:00:00 EST 2020
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Acta neuropathologica communications
Tsai MH,Cheng HY,Nian FS,Liu C,Chao NH,Chiang KL,Chen SF,Tsai JW
Tue Jul 14 00:00:00 EDT 2020
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.
Journal of leukocyte biology
He W,Sun J,Zhang Q,Li Y,Fu Y,Zheng Y,Jiang X
Tue Dec 01 00:00:00 EST 2020
NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes.
Life sciences
Chen F,Zhou Y,Yang K,Shen M,Wang Y
Tue Dec 01 00:00:00 EST 2020
S-allyl-L-cysteine protects hepatocytes from indomethacin-induced apoptosis by attenuating endoplasmic reticulum stress.
FEBS open bio
Chen P,Chen C,Hu M,Cui R,Liu F,Yu H,Ren Y
Tue Sep 01 00:00:00 EDT 2020
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
PloS one
Yeerken D,Hong R,Wang Y,Gong Y,Liu R,Yang D,Li J,Fan J,Chen J,Zhang W,Zhan Q
Wed Sep 09 00:00:00 EDT 2020
Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy.
Journal of ethnopharmacology
Zhang C,Su T,Yu D,Wang F,Yue C,Wang HQ
Mon Oct 05 00:00:00 EDT 2020
Identification and characterization of c-raf from orange-spotted grouper (Epinephelus coioides).
Fish & shellfish immunology
Mo ZQ,Lai XL,Wang WT,Chen HP,He ZC,Han R,Wang JL,Luo XC,Li YW,Dan XM
Wed Jan 01 00:00:00 EST 2020
An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway.
Biology open
Yang ZY,Yang L,Xu CW,Wang XJ,Lei L
Fri Jan 24 00:00:00 EST 2020
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation.
International journal of oncology
Fan Y,Li J,Yang Y,Zhao X,Liu Y,Jiang Y,Zhou L,Feng Y,Yu Y,Cheng Y
Thu Oct 01 00:00:00 EDT 2020
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Oncogenesis
Ma C,Huang S,Xu L,Tian L,Yang Y,Wang J
Fri Mar 06 00:00:00 EST 2020
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Chemosphere
Han Y,Liang C,Manthari RK,Yu Y,Gao Y,Liu Y,Jiang S,Tikka C,Wang J,Zhang J
Wed Jan 01 00:00:00 EST 2020
Intratunical injection of human urine-derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease.
Andrologia
Yang Q,Chen W,Han D,Zhang C,Xie Y,Sun X,Liu G,Deng C
Tue Dec 01 00:00:00 EST 2020
Bu-Yin-Qian-Zheng Formula Ameliorates MPP+-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.
Frontiers in pharmacology
Ma HJ,Gai C,Chai Y,Feng WD,Cheng CC,Zhang JK,Zhang YX,Yang LP,Guo ZY,Gao YS,Sun HM
Tue Jan 12 00:00:00 EST 2021
The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma.
Cell death & disease
Shi ZZ,Wang WJ,Chen YX,Fan ZW,Xie XF,Yang LY,Chang C,Cai Y,Hao JJ,Wang MR,Bai J
Thu Jul 30 00:00:00 EDT 2020
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
Journal of experimental & clinical cancer research : CR
Quan L,Ohgaki R,Hara S,Okuda S,Wei L,Okanishi H,Nagamori S,Endou H,Kanai Y
Mon Nov 30 00:00:00 EST 2020
Involvement of NMDAR/PSD-95/nNOS-NO-cGMP pathway in embryonic exposure to BPA induced learning and memory dysfunction of rats.
Environmental pollution (Barking, Essex : 1987)
Yu H,Ma L,Liu D,Wang Y,Pei X,Duan Z,Ma M,Zhang Y
Sun Nov 01 00:00:00 EDT 2020
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).
Molecular genetics & genomic medicine
Xu Q,Zhu X,Maqsood M,Li W,Tong X,Kong S,Wang F,Liu X,Wei Z,Zhang Z,Zhu F,Cao Y,Bao J
Wed Jul 01 00:00:00 EDT 2020
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Archives of microbiology
Yun S,Guo Y,Yang L,Zhang X,Shen W,Wang Z,Wen S,Zhao D,Wu H,Chen J,Sun Y,Duan Z
Wed Jan 01 00:00:00 EST 2020
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-B Pathway.
The American journal of Chinese medicine
Wu J,Yang CL,Sha YK,Wu Y,Liu ZY,Yuan ZH,Sun ZL
Fri Sep 04 00:00:00 EDT 2020
miR-142-5P regulates triglyceride by targeting CTNNB1 in goat mammary epithelial cells.
Reproduction in domestic animals = Zuchthygiene
Sui M,Wang Z,Xi D,Wang H
Fri May 01 00:00:00 EDT 2020
Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li X,Liu H,Yu W,Liu X,Liu C
Wed Jan 01 00:00:00 EST 2020
BDNF-TrkB pathway mediates antidepressant-like roles of H2 S in diabetic rats via promoting hippocampal autophagy.
Clinical and experimental pharmacology & physiology
Liu HY,Wei HJ,Wu L,Liu SM,Tang YY,Zou W,Wang CY,Zhang P,Tang XQ
Sat Feb 01 00:00:00 EST 2020
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Yu J,Ma C,Xu Y,Han L,Wu X,Wang Y,Deng G
Sun Nov 01 00:00:00 EDT 2020
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type ¿ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Andrology
Liu K,Cui K,Feng H,Li R,Lin H,Chen Y,Zhang Y,Chen Z,Yuan H,Li M,Wang T,Lan R,Liu J,Rao K,Wen B
Sun Mar 01 00:00:00 EST 2020
Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up-regulating ROCK1.
Journal of cellular and molecular medicine
Chen X,Li D,Chen L,Hao B,Gao Y,Li L,Zhou C,He X,Cao Y
Sun Nov 01 00:00:00 EDT 2020
Maternal curcumin supplementation ameliorates placental function and fetal growth in mice with intrauterine growth retardation†.
Biology of reproduction
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Fri Apr 24 00:00:00 EDT 2020
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Innate immunity
Han L,Ma Q,Yu J,Gong Z,Ma C,Xu Y,Deng G,Wu X
Thu Oct 01 00:00:00 EDT 2020
HNF-1a promotes pancreatic cancer growth and apoptosis resistance via its target gene PKLR.
Acta biochimica et biophysica Sinica
Fan Z,Fan K,Deng S,Gong Y,Qian Y,Huang Q,Yang C,Cheng H,Jin K,Luo G,Liu C,Yu X
Wed Mar 18 00:00:00 EDT 2020
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Frontiers in oncology
Yang Z,Huang R,Wei X,Yu W,Min Z,Ye M
Thu Oct 01 00:00:00 EDT 2020
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Nature neuroscience
Shen Q,Chen Z,Zhao F,Pan S,Zhang T,Cheng X,Zhang L,Zhang S,Qi J,Li J,Cai D,Zhang G
Wed Jul 01 00:00:00 EDT 2020
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Toxicology and applied pharmacology
Wang Y,Zhu Y,Niu J,Deng Q,Guo S,Jiang H,Peng Z,Xue Y,Peng H,Xuan L,Pan G
Thu Oct 01 00:00:00 EDT 2020
BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1.
PLoS genetics
Wu S,Ge Y,Li X,Yang Y,Zhou H,Lin K,Zhang Z,Zhao Y
Mon Jun 01 00:00:00 EDT 2020
Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
Cancers
Lyu Y,Kopcho S,Alvarez FA,Okeoma BC,Okeoma CM
Fri Aug 28 00:00:00 EDT 2020
Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
European journal of medicinal chemistry
Liu Y,Zhen Y,Wang G,Yang G,Fu L,Liu B,Ouyang L
Thu Oct 15 00:00:00 EDT 2020
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Parasites & vectors
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Wang LC
Thu Jun 18 00:00:00 EDT 2020
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Life sciences
Liu J,Deng X,Sun X,Dong J,Huang J
Tue Sep 15 00:00:00 EDT 2020
Sustained delivery of PlGF-2123-144*-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
RSC advances
Xiong Z,Cui W,Sun T,Teng Y,Qu Y,Yang L,Zhou J,Chen K,Yao S,Shao Z,Guo X
Thu Feb 13 00:00:00 EST 2020
Catalase is required for peroxisome maintenance during adipogenesis.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Nitta Y,Muraoka-Hirayama S,Sakurai K
Sat Aug 01 00:00:00 EDT 2020
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Journal of natural products
Yang WJ,Chen XM,Wang SQ,Hu HX,Cheng XP,Xu LT,Ren DM,Wang XN,Zhao BB,Lou HX,Shen T
Fri Apr 24 00:00:00 EDT 2020
lncRNA LA16c‑313D11.11 modulates the development of endometrial cancer by binding to and inhibiting microRNA‑205‑5p function and indirectly increasing PTEN activity.
International journal of oncology
Xin W,Zhao S,Han X,Zhao P,Yu H,Gao X,Li P,Wu Q,Ding J,Hua K
Wed Jul 01 00:00:00 EDT 2020
Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.
Brain and behavior
Xu Y,Hu R,He D,Zhou G,Wu H,Xu C,He B,Wu L,Wang Y,Chang Y,Ma R,Xie M,Xiao Z
Wed Jul 01 00:00:00 EDT 2020
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy.
Neural regeneration research
Chen MX,Liu Q,Cheng S,Lei L,Lin AJ,Wei R,K Hui TC,Li Q,Ao LJ,Sham PC
Tue Sep 01 00:00:00 EDT 2020
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Current drug metabolism
Zha A,Cui Z,Qi M,Liao S,Chen L,Liao P,Tan B
Thu Aug 05 00:00:00 EDT 2021
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
Laboratory investigation; a journal of technical methods and pathology
Feng M,Fang F,Fang T,Jiao H,You S,Wang X,Zhao W
Sun Nov 01 00:00:00 EDT 2020
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Life sciences
Chen Y,Niu J,Li L,Li Z,Jiang J,Zhu M,Dong T,Zhang J,Shi C,Xu P,Lu Y,Jiang Y,Liu P,Chen W
Thu Oct 01 00:00:00 EDT 2020
LncRNA HRCEG, regulated by HDAC1, inhibits cells proliferation and epithelial-mesenchymal-transition in gastric cancer.
Cancer genetics
Wu S,Wu E,Wang D,Niu Y,Yue H,Zhang D,Luo J,Chen R
Sat Feb 01 00:00:00 EST 2020
RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis.
ImmunoHorizons
Malireddi RKS,Kesavardhana S,Karki R,Kancharana B,Burton AR,Kanneganti TD
Fri Dec 11 00:00:00 EST 2020
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wei Y,Wang Z,Zong Y,Deng D,Chen P,Lu J
Fri May 01 00:00:00 EDT 2020
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
PloS one
Anchoori RK,Tan M,Tseng SH,Peng S,Soong RS,Algethami A,Foran P,Das S,Wang C,Wang TL,Liang H,Hung CF,Roden RBS
Thu Apr 16 00:00:00 EDT 2020
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Redox biology
Guan R,Wang J,Cai Z,Li Z,Wang L,Li Y,Xu J,Li D,Yao H,Liu W,Deng B,Lu W
Wed Jan 01 00:00:00 EST 2020
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Frontiers in molecular biosciences
Majid A,Wang J,Nawaz M,Abdul S,Ayesha M,Guo C,Liu Q,Liu S,Sun MZ
Sat Oct 24 00:00:00 EDT 2020
Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.
Frontiers in cellular neuroscience
Zhang S,Jin T,Wang L,Liu W,Zhang Y,Zheng Y,Lin Y,Yang M,He X,Lin H,Chen L,Tao J
Mon Sep 28 00:00:00 EDT 2020
Silencing long non‑coding RNA NEAT1 suppresses the tumorigenesis of infantile hemangioma by competitively binding miR‑33a‑5p to stimulate HIF1α/NF‑κB pathway.
Molecular medicine reports
Yu L,Shu H,Xing L,Lv MX,Li L,Xie YC,Zhang Z,Zhang L,Xie YY
Thu Oct 01 00:00:00 EDT 2020
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
Cell reports
De Rossi P,Nomura T,Andrew RJ,Masse NY,Sampathkumar V,Musial TF,Sudwarts A,Recupero AJ,Le Metayer T,Hansen MT,Shim HN,Krause SV,Freedman DJ,Bindokas VP,Kasthuri N,Nicholson DA,Contractor A,Thinakaran G
Tue Mar 10 00:00:00 EDT 2020
The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling.
Neuroscience
Bai J,Zeng S,Zhu J,Fu C,He M,Zhu J,Chen S,Fu X,Li P,Lin Z
Mon Aug 10 00:00:00 EDT 2020
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Oxidative medicine and cellular longevity
Jin M,Feng H,Wang Y,Yan S,Shen B,Li Z,Qin H,Wang Q,Li J,Liu G
Wed May 05 00:00:00 EDT 2021
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Li X,Leng Y,Jiang Q,Wang Z,Luo P,Zhang C,Chen L,Wang Y,Wang H,Yue X,Shen C,Zhou Y,Shi C,Xie L
Mon Sep 28 00:00:00 EDT 2020
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Oxidative medicine and cellular longevity
Luan Y,Cui K,Tang Z,Ruan Y,Liu K,Wang T,Chen Z,Wang S,Liu J
Tue Nov 10 00:00:00 EST 2020
Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.
Life sciences
Wang M,Dong Y,Wu J,Li H,Zhang Y,Fan S,Li D
Sun Nov 15 00:00:00 EST 2020
PDE9 inhibition promotes proliferation of neural stem cells via cGMP-PKG pathway following oxygen-glucose deprivation/reoxygenation injury in vitro.
Neurochemistry international
Huan X,Oumei C,Hongmei Q,Junxia Y,Xiaojiao M,Qingsong J
Sat Feb 01 00:00:00 EST 2020
Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.
Theranostics
Zhen Y,Zhao R,Wang M,Jiang X,Gao F,Fu L,Zhang L,Zhou XL
Mon May 03 00:00:00 EDT 2021
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
DNA and cell biology
Zhang J,Chen Y,Lin J,Jia R,An T,Dong T,Zhang Y,Yang X
Sun Mar 01 00:00:00 EST 2020
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Life sciences
Dong D,Dong Y,Fu J,Lu S,Yuan C,Xia M,Sun L
Sat Aug 15 00:00:00 EDT 2020
Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.
Evidence-based complementary and alternative medicine : eCAM
Zou Z,Sun J,Kang Z,Wang Y,Zhao H,Zhu K,Wang J
Mon Sep 28 00:00:00 EDT 2020
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
European journal of pharmacology
Zhang H,Hui J,Yang J,Deng J,Fan D
Sun Nov 15 00:00:00 EST 2020
Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition.
Journal of cellular physiology
You P,Cheng Z,He X,Deng J,Diao J,Chen H,Cheng G
Fri May 01 00:00:00 EDT 2020
Inhibition of CACNA1H can alleviate endoplasmic reticulum stress and reduce myocardial cell apoptosis caused by myocardial infarction.
European review for medical and pharmacological sciences
Wang MX,Liu X,Li JM,Liu L,Lu W,Chen GC
Tue Dec 01 00:00:00 EST 2020
Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li B,Zang G,Zhong W,Chen R,Zhang Y,Yang P,Yan J
Wed Jan 01 00:00:00 EST 2020
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Free radical biology & medicine
Zhang D,Liu Y,Luo Z,Chen Y,Xu A,Liang Y,Wu B,Tong X,Liu X,Shen H,Liu L,Wei Y,Zhou H,Liu Y,Zhou F
Wed Jan 01 00:00:00 EST 2020
Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2.
Frontiers in cell and developmental biology
Jiang X,Li Y,Feng JL,Nik Nabil WN,Wu R,Lu Y,Liu H,Xi ZC,Xu HX
Tue Jan 05 00:00:00 EST 2021
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.
Molecular carcinogenesis
Liu K,Hu H,Jiang H,Liu C,Zhang H,Gong S,Wei D,Yu Z
Thu Oct 01 00:00:00 EDT 2020
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation.
Molecular cell
Huo X,Ji L,Zhang Y,Lv P,Cao X,Wang Q,Yan Z,Dong S,Du D,Zhang F,Wei G,Liu Y,Wen B
Thu Jan 16 00:00:00 EST 2020
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Experimental cell research
Tu J,Zhang B,Fang G,Chang W,Zhao Y
Fri May 15 00:00:00 EDT 2020
Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function.
Frontiers in pharmacology
Yao R,Pan R,Shang C,Li X,Cheng J,Xu J,Li Y
Mon Sep 28 00:00:00 EDT 2020
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Oxidative medicine and cellular longevity
Wang P,Zhao M,Chen Z,Wu G,Fujino M,Zhang C,Zhou W,Zhao M,Hirano SI,Li XK,Zhao L
Fri Nov 06 00:00:00 EST 2020
P-21-activated kinase 1 contributes to tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway.
Biochemical and biophysical research communications
Jiang S,Gao Y,Yu QH,Li M,Cheng X,Hu SB,Song ZF,Zheng QC
Thu May 21 00:00:00 EDT 2020
Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling.
Frontiers in psychiatry
Li X,Qiu W,Li N,Da X,Ma Q,Hou Y,Wang T,Song M,Chen J
Mon Sep 28 00:00:00 EDT 2020
K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711.
Biochemical and biophysical research communications
Jiang YH,Liu J,Lin J,Li SQ,Xu YM,Min QH,Zhong QH,Sun F,Li J,You XH,Liao KL,Qin TY,Zhao C,Huang B,Wang XZ
Wed Jan 15 00:00:00 EST 2020
Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.
Molecular neurobiology
Zhou C,Taslima F,Abdelhamid M,Kim SW,Akatsu H,Michikawa M,Jung CG
Sat Feb 01 00:00:00 EST 2020
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Oncology letters
Liu C,Wang F,Wang B,Wu T,Wang Y,Huo W,Zhang S,Su Y,Liu J,Liu Y,Yu J
Tue Dec 01 00:00:00 EST 2020
LncRNA GAS5 exacerbates renal tubular epithelial fibrosis by acting as a competing endogenous RNA of miR-96-5p.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang W,Jia YJ,Yang YL,Xue M,Zheng ZJ,Wang L,Xue YM
Wed Jan 01 00:00:00 EST 2020
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
American journal of cancer research
Fan L,Wang J,Cao Q,Ding X,Li B
Mon Nov 13 00:00:00 EST 2023
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Journal of cellular physiology
Li L,Xu L,Wen S,Yang Y,Li X,Fan Q
Wed Jul 01 00:00:00 EDT 2020
Visualization of translocator protein (18 kDa) (TSPO) in the retina of diabetic retinopathy rats using fluorine-18-DPA-714.
Annals of nuclear medicine
Zhou Y,Ou Y,Ju Z,Zhang X,Zheng L,Li J,Sun Y,Liu X
Tue Sep 01 00:00:00 EDT 2020
C2C12 Mouse Myoblasts Damage Induced by Oxidative Stress Is Alleviated by the Antioxidant Capacity of the Active Substance Phloretin.
Frontiers in cell and developmental biology
Li J,Yang Q,Han L,Pan C,Lei C,Chen H,Lan X
Tue Oct 13 00:00:00 EDT 2020
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Journal of cellular physiology
Guan GY,Wei N,Song T,Zhao C,Sun Y,Pan RX,Zhang LL,Xu YY,Dai YM,Han H
Tue Dec 01 00:00:00 EST 2020
Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition via Inhibition NLRP3 Inflammasome.
Biological & pharmaceutical bulletin
Liu Y,Chen X,Gong Q,Shi J,Li F
Wed Jun 16 00:00:00 EDT 2021
miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway.
Frontiers in cell and developmental biology
Cui Y,Chen R,Ma L,Yang W,Chen M,Zhang Y,Yu S,Dong W,Zeng W,Lan X,Pan C
Mon Sep 28 00:00:00 EDT 2020
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Sat Feb 01 00:00:00 EST 2020
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
The journal of headache and pain
Long T,He W,Pan Q,Zhang S,Zhang D,Qin G,Chen L,Zhou J
Tue Jan 14 00:00:00 EST 2020
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Therapeutic advances in chronic disease
Miao K,Pan T,Mou Y,Zhang L,Xiong W,Xu Y,Yu J,Wang Y
Sat Apr 16 00:00:00 EDT 2022
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
Biochemical and biophysical research communications
Wu J,Zhao Y,Fan Z,Chen Q,Chen J,Sun Y,Jiang X,Xiao Q
Thu Apr 02 00:00:00 EDT 2020
5-HT1AR alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
International immunopharmacology
Wang M,Zong HF,Chang KW,Han H,Yasir Rizvi M,Iffat Neha S,Li ZY,Yang WN,Qian YH
Tue Mar 03 00:00:00 EST 2020
Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.
Sensors (Basel, Switzerland)
Oladzad A,Nikkhah M,Hosseinkhani S
Mon Mar 23 00:00:00 EDT 2020
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Cellular and molecular neurobiology
Luo Z,Wang H,Fang S,Li L,Li X,Shi J,Zhu M,Tan Z,Lu Z
Fri May 01 00:00:00 EDT 2020
Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Oxidative medicine and cellular longevity
Yuan M,Gong M,Zhang Z,Meng L,Tse G,Zhao Y,Bao Q,Zhang Y,Yuan M,Liu X,Li G,Liu T
Thu May 13 00:00:00 EDT 2021
Velvet antler polypeptide prevents the disruption of hepatic tight junctions via inhibiting oxidative stress in cholestatic mice and liver cell lines.
Food & function
Li L,Yang F,Jia R,Yan P,Ma L
Wed Nov 18 00:00:00 EST 2020
Fast and unbiased purification of RNA-protein complexes after UV cross-linking.
Methods (San Diego, Calif.)
Urdaneta EC,Beckmann BM
Mon Jun 01 00:00:00 EDT 2020
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer.
BMC cancer
Sizemore G,McLaughlin S,Newman M,Brundage K,Ammer A,Martin K,Pugacheva E,Coad J,Mattes MD,Yu HG
Fri Jun 26 00:00:00 EDT 2020
Transcriptome sequencing analysis of mono‑ADP‑ribosylation in colorectal cancer cells.
Oncology reports
Zhang NN,Lin T,Xiao M,Li QS,Li X,Yang L,Wang CL,Wang YL
Fri May 01 00:00:00 EDT 2020
Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway.
Archives of oral biology
Liu J,Yang H,Zhang H,Liu Q,Zhou P,He F,Zhang M,Yu S,Liu J,Wang M
Thu Oct 01 00:00:00 EDT 2020
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
Journal of cellular physiology
Miao R,Dai CC,Mei L,Xu J,Sun SW,Xing YL,Wu LS,Wang MH,Wei JF
Thu Oct 01 00:00:00 EDT 2020
SUMOylation of vascular endothelial growth factor receptor 2 inhibits the proliferation, migration, and angiogenesis signaling pathway in non-small cell lung cancer.
Anti-cancer drugs
Wang M,Jiang X
Mon Jun 01 00:00:00 EDT 2020
Regulatory effects of Prohibitin 1 on proliferation and apoptosis of pulmonary arterial smooth muscle cells in monocrotaline-induced PAH rats.
Life sciences
Cao YY,Ba HX,Li Y,Tang SY,Luo ZQ,Li XH
Mon Jun 01 00:00:00 EDT 2020
TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling.
Discovery medicine
Guo Y,Cao F,Hu S,Liu S,Sun H,Li A,Li F
Mon Oct 25 00:00:00 EDT 2021
Myxovirus resistance (Mx) gene and its differential expression regulated by three type I and two type II IFNs in mandarin fish, Siniperca chuatsi.
Developmental and comparative immunology
Li L,Chen SN,Laghari ZA,Huo HJ,Hou J,Huang L,Li N,Nie P
Wed Apr 01 00:00:00 EDT 2020
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2.
Carcinogenesis
Jin M,Ren J,Luo M,You Z,Fang Y,Han Y,Li G,Liu H
Fri Jul 10 00:00:00 EDT 2020
LKB1-MARK2 signalling mediates lipopolysaccharide-induced production of cytokines in mouse macrophages.
Journal of cellular and molecular medicine
Deng J,Wen C,Ding X,Zhang X,Hou G,Liu A,Xu H,Cao X,Bai Y
Thu Oct 01 00:00:00 EDT 2020
Protein kinase CK2 participates in estrogen-mediated endothelial progenitor cell homing to endometriotic lesions through stromal cells in a stromal cell-derived factor-1- CXCR4-dependent manner.
Fertility and sterility
Zhao R,Feng D,Zhuang G,Liu Y,Chi S,Zhang J,Zhou X,Zhang W,Wang H
Fri May 01 00:00:00 EDT 2020
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Frontiers in pharmacology
Xie T,Wang C,Jin Y,Meng Q,Liu Q,Wu J,Sun H
Mon Sep 28 00:00:00 EDT 2020
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Journal of cellular and molecular medicine
Zhou L,Sheng W,Jia C,Shi X,Cao R,Wang G,Lin Y,Zhu F,Dong Q,Dong M
Tue Sep 01 00:00:00 EDT 2020
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Shi Y,Li F,Wang S,Wang C,Xie Y,Zhou J,Li X,Wang B
Wed Jul 01 00:00:00 EDT 2020
TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture.
Biochimica et biophysica acta. Gene regulatory mechanisms
Ji L,Huo X,Zhang Y,Yan Z,Wang Q,Wen B
Fri May 01 00:00:00 EDT 2020
Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.
Biopharmaceutics & drug disposition
Kim Y,Jo JJ,Cho P,Shrestha R,Kim KM,Ki SH,Song KS,Liu KH,Song IS,Kim JH,Lee JM,Lee S
Wed Jul 01 00:00:00 EDT 2020
Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro.
BMC complementary medicine and therapies
Dai GH,Chen X,Ren ZM,Dai CJ,Tong YL,Chai KQ
Thu Sep 03 00:00:00 EDT 2020
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.
Drug design, development and therapy
Jiang Y,Bian Y,Lian N,Wang Y,Xie K,Qin C,Yu Y
Mon Aug 23 00:00:00 EDT 2021
Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling.
Journal of drug targeting
Wang M,Li C,Shi W
Wed Jul 01 00:00:00 EDT 2020
Association between different levels of lipid metabolism‑related enzymes and fatty acid synthase in Wilms' tumor.
International journal of oncology
Wang X,Du G,Wu Y,Zhang Y,Guo F,Liu W,Wu R
Sat Feb 01 00:00:00 EST 2020
Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells.
Experimental and therapeutic medicine
Wang W,Huang F,Jiang W,Wang W,Xiang J
Sun Nov 01 00:00:00 EDT 2020
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
IUBMB life
Shan X,Dong W,Zhang L,Cai X,Zhao Y,Chen Q,Yan Q,Liu J
Fri May 01 00:00:00 EDT 2020
SNHG9 was upregulated in NSCLC and associated with DDP-resistance and poor prognosis of NSCLC patients.
American journal of translational research
Wang R,Chen C,Kang W,Meng G
Mon Sep 28 00:00:00 EDT 2020
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
The Journal of pharmacy and pharmacology
Xu J,Xiang P,Liu L,Sun J,Ye S
Sat Aug 01 00:00:00 EDT 2020
The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16Ink4a suppressing STAT3 activity.
Journal of cellular physiology
Wang X,Zhang S,Dong M,Li Y,Zhou Q,Yang L
Tue Dec 01 00:00:00 EST 2020
CaMKII as a key regulator of contrast-induced nephropathy through mPTP opening in HK-2 cells.
Cellular signalling
Hu C,Zhou G,Liu K,Yin W,Zhou L,Wang J,Chen L,Zuo S,Xie Y,Zuo X
Sun Nov 01 00:00:00 EDT 2020
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way.
Cancer cell international
Huang R,Zhu L,Zhang Y
Sun Nov 12 00:00:00 EST 2023
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Frontiers in cell and developmental biology
Chen X,Deng S,Lei Q,He Q,Ren Y,Zhang Y,Nie J,Lu W
Tue Jan 05 00:00:00 EST 2021
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Molecular cell
Yuan Y,Miao Y,Qian L,Zhang Y,Liu C,Liu J,Zuo Y,Feng Q,Guo T,Zhang L,Chen X,Jin L,Huang F,Zhang H,Zhang W,Li W,Xu G,Zheng H
Thu Feb 20 00:00:00 EST 2020
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Life sciences
Zhang Y,Liu X,Yu M,Xu M,Xiao Y,Ma W,Huang L,Li X,Ye X
Sun Nov 01 00:00:00 EDT 2020
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Cell & bioscience
Yao W,Jiao Y,Zhou Y,Luo X
Fri Apr 15 00:00:00 EDT 2022
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Frontiers in psychiatry
Song M,Zhang J,Li X,Liu Y,Wang T,Yan Z,Chen J
Mon Apr 18 00:00:00 EDT 2022
NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis.
International immunopharmacology
Zhang J,Jiang N,Zhang L,Meng C,Zhao J,Wu J
Sun Mar 01 00:00:00 EST 2020
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway.
Bioscience reports
Zhang Q,Cheng S,Cao L,Yang J,Wang Y,Chen Y
Fri Mar 27 00:00:00 EDT 2020
(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis.
Cell death & disease
Wang M,Liu CY,Wang T,Yu HM,Ouyang SH,Wu YP,Gong HB,Ma XH,Jiao GL,Fu LL,Wu QS,Kurihara H,Li YF,Shen T,He RR
Sat Sep 19 00:00:00 EDT 2020
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Nature communications
Liu Y,Zhang Y,Li T,Han J,Wang Y
Thu Jan 30 00:00:00 EST 2020
PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E2-Mediated Inhibition of IgE Production in Asthma.
Frontiers in immunology
Wu J,Wang Y,Zhou Y,Wang Y,Sun X,Zhao Y,Guan Y,Zhang Y,Wang W
Mon Apr 05 00:00:00 EDT 2021
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
Life sciences
Li Z,Lian Y,Wei R,Jin L,Cao H,Zhao T,Ma X,Zhong M,Gao Y,Zhang K
Tue Dec 01 00:00:00 EST 2020
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
OncoTargets and therapy
Hu X,Wang J,Chai J,Yu X,Zhang Y,Feng Y,Qin J,Yu H
Sun Apr 17 00:00:00 EDT 2022
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
European review for medical and pharmacological sciences
Li XW,He RZ,Li Y,Ruan ZF
Mon Jun 01 00:00:00 EDT 2020
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Cell proliferation
Guan Z,Wang Y,Wang Y,Liu X,Wang Y,Zhang W,Chi X,Dong Y,Liu X,Shao S,Zhan Q
Wed Apr 01 00:00:00 EDT 2020
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
OncoTargets and therapy
Zeng Z,Lan J,Lei S,Yang Y,He Z,Xue Y,Chen T
Mon Apr 18 00:00:00 EDT 2022
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen.
Medicines (Basel, Switzerland)
Takeuchi Y,Tanaka M,Okura N,Fukui Y,Noguchi K,Hayashi Y,Torii T,Ooizumi H,Ohbuchi K,Mizoguchi K,Miyamoto Y,Yamauchi J
Wed May 06 00:00:00 EDT 2020
miR-17 regulates the proliferation and differentiation of retinal progenitor cells by targeting CHMP1A.
Biochemical and biophysical research communications
Sun N,Zhang D,Ni N,Tang Z,Gao H,Ju Y,Dai X,Wang J,Gu P,Ji J
Thu Mar 05 00:00:00 EST 2020
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
Biochemical and biophysical research communications
Tu Y,Ma T,Wen T,Yang T,Xue L,Cai M,Wang F,Guan M,Xue H
Wed Feb 26 00:00:00 EST 2020
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
Food & function
Chen Z,Chu S,Liang Y,Xu T,Sun Y,Li M,Zhang H,Wang X,Mao Y,Loor JJ,Wu Y,Yang Z
Wed Oct 21 00:00:00 EDT 2020
miR-143-3p inhibition promotes neuronal survival in an Alzheimer's disease cell model by targeting neuregulin-1.
Folia neuropathologica
Sun C,Jia N,Li R,Zhang Z,Zhong Y,Han K
Thu Feb 04 00:00:00 EST 2021
Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1.
Cell cycle (Georgetown, Tex.)
Guo Y,Sun J,Bu S,Li B,Zhang Q,Wang Q,Lai D
Wed Jul 01 00:00:00 EDT 2020
H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity.
Journal of neurochemistry
Kim Y,Stahl MC,Huang X,Connor JR
Tue Sep 01 00:00:00 EDT 2020
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
Cancers
Liu F,Kalpage HA,Wang D,Edwards H,Hüttemann M,Ma J,Su Y,Carter J,Li X,Polin L,Kushner J,Dzinic SH,White K,Wang G,Taub JW,Ge Y
Mon Aug 24 00:00:00 EDT 2020
Upregulation of Glutaredoxin 2 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and ROS production in neurons by enhancing Nrf2 signaling via modulation of GSK-3β.
Brain research
Wen J,Li X,Zheng S,Xiao Y
Thu Oct 15 00:00:00 EDT 2020
Dual regulation of p53 by the ribosome maturation factor SBDS.
Cell death & disease
Hao Q,Wang J,Chen Y,Wang S,Cao M,Lu H,Zhou X
Fri Mar 20 00:00:00 EDT 2020
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
Frontiers in veterinary science
Zhao C,Bobe G,Wang Y,Zhang X,Zhao Z,Zhang S,Sun G,Yuan X,Li X,Liu G
Mon Sep 28 00:00:00 EDT 2020
TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC.
Frontiers in oncology
Zhong M,Qiu X,Liu Y,Yang Y,Gu L,Wang C,Chen H,Liu Z,Miao J,Zhuang G
Tue Mar 16 00:00:00 EDT 2021
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Nucleic acids research
Kalasova I,Hailstone R,Bublitz J,Bogantes J,Hofmann W,Leal A,Hanzlikova H,Caldecott KW
Thu Jul 09 00:00:00 EDT 2020
Hypouricemic Effects of Extracts from Urtica hyperborea Jacq. ex Wedd. in Hyperuricemia Mice through XOD, URAT1, and OAT1.
BioMed research international
Han S,Wei R,Han D,Zhu J,Luo W,Ao W,Zhong G
Mon Oct 26 00:00:00 EDT 2020
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Aging
Tang D,Liu X,Chen K,Li Z,Dai Y,Xu J,Zhang HT,Gao X,Liu L
Sat Jun 27 00:00:00 EDT 2020
Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Asian Pacific journal of cancer prevention : APJCP
Abozaid OAR,Moawed FSM,Farrag MA,Kawara RSM
Mon Jun 01 00:00:00 EDT 2020
Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein.
Journal of virology
Lukash T,Agback T,Dominguez F,Shiliaev N,Meshram C,Frolova EI,Agback P,Frolov I
Wed Dec 09 00:00:00 EST 2020
Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS.
Free radical research
Zhao T,Zhang-Akiyama QM
Tue Sep 01 00:00:00 EDT 2020
LHPP inhibits hepatocellular carcinoma cell growth and metastasis.
Cell cycle (Georgetown, Tex.)
Liao L,Duan D,Liu Y,Chen L
Wed Jul 01 00:00:00 EDT 2020
Regulation of the firing activity by PKA-PKC-Src family kinases in cultured neurons of hypothalamic arcuate nucleus.
Journal of neuroscience research
Sun XD,Wang A,Ma P,Gong S,Tao J,Yu XM,Jiang X
Sat Feb 01 00:00:00 EST 2020
Combination of N, N'-dicyclohexyl-N-arachidonic acylurea and tacrolimus prolongs cardiac allograft survival in mice.
Immunology and cell biology
An K,Qin Q,Yu S,Xue M,Wang Z,Lin Q,Ma Y,Yan G,Mo S,Chen Y,Zhang L,Zhong J,Qi Z,Xia J
Fri May 01 00:00:00 EDT 2020
microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
Frontiers in immunology
Liu C,Ye MY,Yan WZ,Peng XF,He LY,Peng YM
Mon May 03 00:00:00 EDT 2021
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
The American journal of Chinese medicine
Yen IC,Lin JC,Chen Y,Tu QW,Lee SY
Fri May 28 00:00:00 EDT 2021
AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.
Virus research
Lai Q,Xu L,Wang Y,Luo W,Zhu L,Yuan M,Wu W,Yang K
Thu Apr 02 00:00:00 EDT 2020
Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling.
OncoTargets and therapy
Chen ZL,Li XN,Ye CX,Chen HY,Wang ZJ
Thu Apr 14 00:00:00 EDT 2022
Cytotoxic effects of vitamins K1, K2, and K3 against human T lymphoblastoid leukemia cells through apoptosis induction and cell cycle arrest.
Chemical biology & drug design
Xu W,Wu H,Chen S,Wang X,Tanaka S,Sugiyama K,Yamada H,Hirano T
Thu Oct 01 00:00:00 EDT 2020
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Molecular therapy. Nucleic acids
Guo X,Dai X,Liu J,Cheng A,Qin C,Wang Z
Fri Sep 04 00:00:00 EDT 2020
Tolfenamic acid inhibits GSK-3β and PP2A mediated tau hyperphosphorylation in Alzheimer's disease models.
The journal of physiological sciences : JPS
Zhang H,Wang X,Xu P,Ji X,Chi T,Liu P,Zou L
Tue Jun 09 00:00:00 EDT 2020
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Theranostics
Zhang K,Dong C,Chen M,Yang T,Wang X,Gao Y,Wang L,Wen Y,Chen G,Wang X,Yu X,Zhang Y,Wang P,Shang M,Han K,Zhou Y
Fri Apr 02 00:00:00 EDT 2021
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Pharmacological research
Mei D,Tan WSD,Liao W,Heng CKM,Wong WSF
Sun Nov 01 00:00:00 EDT 2020
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells.
Molecular and cellular neurosciences
Lyons EL,Leone-Kabler S,Kovach AL,Thomas BF,Howlett AC
Tue Dec 01 00:00:00 EST 2020
Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR.
Journal of ethnopharmacology
Xu JB,Gao GC,Yuan MJ,Huang X,Zhou HY,Zhang Y,Zheng YX,Wu Z,Feng JM,Wu JM
Mon Aug 10 00:00:00 EDT 2020
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
International journal of biological macromolecules
Yang K,Lu T,Zhan L,Zhou C,Zhang N,Lei S,Wang Y,Yang J,Yan M,Lv G,Chen S
Wed Apr 15 00:00:00 EDT 2020
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335.
OncoTargets and therapy
Yang F,Tang Z,Duan A,Yi B,Shen N,Bo Z,Yin L,Zhu B,Qiu Y,Li J
Wed Apr 13 00:00:00 EDT 2022
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Journal of cellular physiology
Zhu HD,Liu L,Deng H,Li ZB,Sheng JQ,He XX,Tian DA,Li PY
Mon Jun 01 00:00:00 EDT 2020
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Naunyn-Schmiedeberg's archives of pharmacology
Tong R,Zhang J,Wang C,Li Q,Wang L,Ju M
Mon Jun 01 00:00:00 EDT 2020
GOLPH3 Regulates Exosome miRNA Secretion in Glioma Cells.
Journal of molecular neuroscience : MN
Hu P,Wang K,Zhou D,Wang L,Zhao M,Wang W,Zhang Y,Liu Y,Yu R,Zhou X
Sat Aug 01 00:00:00 EDT 2020
Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.
Oncology reports
Qi W,Li Z,Yang C,Jiangshan Dai J,Zhang Q,Wang D,Wu C,Xia L,Xu S
Sun Mar 01 00:00:00 EST 2020
A protective role of renalase in diabetic nephropathy.
Clinical science (London, England : 1979)
Yin J,Liu X,Zhao T,Liang R,Wu R,Zhang F,Kong Y,Liu L,Xing T,Wang N,Zhao Q,Wang F
Fri Jan 17 00:00:00 EST 2020
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Autoimmunity
Li D,Li X,Duan M,Dou Y,Feng Y,Nan N,Zhang W
Mon Jun 01 00:00:00 EDT 2020
Anthocyanins decrease the internalization of TiO2 nanoparticles into 3D Caco-2 spheroids.
Food chemistry
Wang J,Zhang J,Li S,Huang C,Xie Y,Cao Y
Mon Nov 30 00:00:00 EST 2020
Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2.
Frontiers in cell and developmental biology
Chu Y,Chen W,Peng W,Liu Y,Xu L,Zuo J,Zhou J,Zhang Y,Zhang N,Li J,Liu L,Yao K,Gao G,Wang X,Han R,Liu C,Li Y,Zhou H,Huang Y,Ye Y
Sat Dec 12 00:00:00 EST 2020
Effect of fluoride on osteocyte-driven osteoclastic differentiation.
Toxicology
Jiang N,Guo F,Xu W,Zhang Z,Jin H,Shi L,Zhang X,Gao J,Xu H
Thu Apr 30 00:00:00 EDT 2020
Heme Oxygenase-1-Mediated Autophagy Protects against Oxidative Damage in Rat Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Oxidative medicine and cellular longevity
Chen S,Liu S,Zhao L,Lin H,Ma K,Shao Z
Tue Nov 10 00:00:00 EST 2020
Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
The Journal of biological chemistry
Wortham AM,Goldman DC,Chen J,Fleming WH,Zhang AS,Enns CA
Fri Mar 20 00:00:00 EDT 2020
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund's Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
He P,Hu Y,Huang C,Wang X,Zhang H,Zhang X,Dai H,Wang R,Gao Y
Mon Sep 28 00:00:00 EDT 2020
ARHGEF38 as a novel biomarker to predict aggressive prostate cancer.
Genes & diseases
Liu K,Wang A,Ran L,Zhang W,Jing S,Wang Y,Zhang X,Liu G,Sen W,Song F
Mon Jun 01 00:00:00 EDT 2020
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Journal of tissue engineering and regenerative medicine
Li J,Gao F,Ma S,Zhang Y,Zhang J,Guan F,Yao M
Tue Sep 01 00:00:00 EDT 2020
Estrogen Exerts Neuroprotective Effects in Vascular Dementia Rats by Suppressing Autophagy and Activating the Wnt/β-Catenin Signaling Pathway.
Neurochemical research
Yang Y,Zhao L,Li N,Dai C,Yin N,Chu Z,Duan X,Niu X,Yan P,Lv P
Tue Sep 01 00:00:00 EDT 2020
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
ACS nano
Zhu J,Li B,Xu M,Liu R,Xia T,Zhang Z,Xu Y,Liu S
Tue Jan 28 00:00:00 EST 2020
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Virus genes
Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J
Tue Dec 01 00:00:00 EST 2020
Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.
Journal of Zhejiang University. Science. B
Yang F,Liu WW,Chen H,Zhu J,Huang AH,Zhou F,Gan Y,Zhang YH,Ma L
Mon Nov 23 00:00:00 EST 2020
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
International journal of oncology
Tang Y,Chen K,Luan X,Zhang J,Liu R,Zheng X,Xie S,Ke H,Zhang X,Chen W
Tue Dec 01 00:00:00 EST 2020
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
EBioMedicine
Zhang S,Bao Y,Shen X,Pan Y,Sun Y,Xiao M,Chen K,Wei H,Zuo J,Saffen D,Zong WX,Sun Y,Wang Z,Wang Y
Sun Nov 01 00:00:00 EDT 2020
Suppression of experimental atrial fibrillation in a canine model of rapid atrial pacing by the phosphodiesterase 3 inhibitor cilostazol.
Journal of electrocardiology
Zhao Z,Li R,Wang X,Li J,Xu X,Liu T,Liu E,Li G
Mon Jun 21 00:00:00 EDT 2021
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
Journal of proteome research
Meng K,Lu S,Yan X,Sun Y,Gao J,Wang Y,Yin X,Sun Z,He QY
Fri Mar 06 00:00:00 EST 2020
Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Yi X,Wu L,Liu J,Qin YX,Li B,Zhou Q
Sun Nov 01 00:00:00 EDT 2020
Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress.
Journal of experimental & clinical cancer research : CR
Sheng W,Wang G,Tang J,Shi X,Cao R,Sun J,Lin YH,Jia C,Chen C,Zhou J,Dong M
Wed Oct 07 00:00:00 EDT 2020
Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway.
Environmental pollution (Barking, Essex : 1987)
Liu J,Yang B,Wang Y,Wu Y,Fan B,Zhu S,Song E,Song Y
Sat Feb 01 00:00:00 EST 2020
The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer.
Oxidative medicine and cellular longevity
Deng X,Lin N,Fu J,Xu L,Luo H,Jin Y,Liu Y,Sun L,Su J
Tue Jun 08 00:00:00 EDT 2021
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Frontiers in cellular and infection microbiology
Wang T,Zhang P,Lv H,Deng X,Wang J
Thu Jun 17 00:00:00 EDT 2021
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xia B,Yu J,He T,Liu X,Su J,Wang M,Wang J,Zhu Y
Sat Feb 01 00:00:00 EST 2020
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
International journal of biological macromolecules
Luo J,Zhang R,Wang X,Hou Z,Guo S,Jiang B
Sun Nov 15 00:00:00 EST 2020
MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
Neurochemical research
Zhao J,Guo X,Wang B,Yang Z,Huang T,Guo D,Zhang M,Song J
Tue Sep 01 00:00:00 EDT 2020
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xu Y,Li X,Cheng Y,Yang M,Wang R
Tue Dec 01 00:00:00 EST 2020
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
PLoS pathogens
Wang X,Wu Z,Li Y,Yang Y,Xiao C,Liu X,Xiang X,Wei J,Shao D,Liu K,Deng X,Wu J,Qiu Y,Li B,Ma Z
Thu Oct 01 00:00:00 EDT 2020
Integrin β3 Modulates TLR4-Mediated Inflammation by Regulation of CD14 Expression in Macrophages in Septic Condition.
Shock (Augusta, Ga.)
Chen Z,Wang S,Chen Y,Shao Z,Yu Z,Mei S,Li Q
Sun Mar 01 00:00:00 EST 2020
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Journal of biomedical materials research. Part A
Zhang K,Bai Y,Xu R,Li J,Guan F
Sun Mar 01 00:00:00 EST 2020
Integrin α1 promotes tumorigenicity and progressive capacity of colorectal cancer.
International journal of biological sciences
Li H,Wang Y,Rong SK,Li L,Chen T,Fan YY,Wang YF,Yang CR,Yang C,Cho WC,Yang J
Mon Jun 07 00:00:00 EDT 2021
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Cell proliferation
Ni S,Qian Z,Yuan Y,Li D,Zhong Z,Ghorbani F,Zhang X,Zhang F,Zhang Z,Liu Z,Yu B
Thu Oct 01 00:00:00 EDT 2020
NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
Molecular oncology
Xia J,He Y,Meng B,Chen S,Zhang J,Wu X,Zhu Y,Shen Y,Feng X,Guan Y,Kuang C,Guo J,Lei Q,Wu Y,An G,Li G,Qiu L,Zhan F,Zhou W
Wed Apr 01 00:00:00 EDT 2020
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
Drug design, development and therapy
Yao R,Xie Y,Sun X,Zhang M,Zhou J,Liu L,Gao J,Xu K
Thu Jul 15 00:00:00 EDT 2021
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways.
International journal of biological macromolecules
Zhong J,Qiu X,Yu Q,Chen H,Yan C
Sun Nov 15 00:00:00 EST 2020
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice.
European journal of pharmacology
Bai XY,Liu P,Chai YW,Wang Y,Ren SH,Li YY,Zhou H
Tue May 05 00:00:00 EDT 2020
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Toxicology letters
Yang L,Sun YY,Liu YR,Yin NN,Bu FT,Yu HX,Du XS,Li J,Huang C
Sat Feb 01 00:00:00 EST 2020
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
FEBS open bio
Chen M,Li S,Hao M,Chen J,Zhao Z,Hong S,Min J,Tang J,Hu M,Hong L
Thu Oct 01 00:00:00 EDT 2020
Hypoxia induces sorafenib resistance mediated by autophagy via activating FOXO3a in hepatocellular carcinoma.
Cell death & disease
Liang C,Dong Z,Cai X,Shen J,Xu Y,Zhang M,Li H,Yu W,Chen W
Sun Nov 29 00:00:00 EST 2020
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3).
Gene
Zhang S,Zhang R,Xu R,Shang J,He H,Yang Q
Sun Apr 05 00:00:00 EDT 2020
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX.
Experimental and therapeutic medicine
Yuan M,Zhao S,Chen R,Wang G,Bie Y,Wu Q,Cheng J
Wed Jan 01 00:00:00 EST 2020
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.
Aging
Wu Y,Xia L,Zhao P,Deng Y,Guo Q,Zhu J,Chen X,Ju X,Wu X
Tue Jun 16 00:00:00 EDT 2020
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Wang J,Fang Z,Song C,Kang H,Guo Q,Dong Y,Zhang Y,Peng R,Guan H,Li F
Mon Sep 28 00:00:00 EDT 2020
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Journal of molecular medicine (Berlin, Germany)
Li N,Luo X,Yu Q,Yang P,Chen Z,Wang X,Jiang J,Xu J,Gong Q,Eizirik DL,Zhou Z,Zhao J,Xiong F,Zhang S,Wang CY
Tue Dec 01 00:00:00 EST 2020
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
Experimental and therapeutic medicine
Liao D,Zhang C,Liu N,Cao L,Wang C,Feng Q,Yao D,Long M,Jiang P
Sat Feb 01 00:00:00 EST 2020
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation.
Cell reports
Bi Y,Tu Z,Zhang Y,Yang P,Guo M,Zhu X,Zhao C,Zhou J,Wang H,Wang Y,Gao S
Tue Mar 17 00:00:00 EDT 2020
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Nature communications
Li X,Zhang M,Huang X,Liang W,Li G,Lu X,Li Y,Pan H,Shi L,Zhu H,Qian L,Shan B,Yuan J
Fri Dec 11 00:00:00 EST 2020
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
The Journal of biological chemistry
Underwood R,Wang B,Carico C,Whitaker RH,Placzek WJ,Yacoubian TA
Fri Jun 05 00:00:00 EDT 2020
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis.
Scientific reports
Wang J,Jiang D,Li Z,Yang S,Zhou J,Zhang G,Zhang Z,Sun Y,Zhang Z,Li X,Tao L,Shi J,Lu Y,Zheng L,Song C,Yang K
Wed Mar 04 00:00:00 EST 2020
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
European journal of medicinal chemistry
Yang J,Hu S,Wang C,Song J,Chen C,Fan Y,Ben-David Y,Pan W
Wed Jan 15 00:00:00 EST 2020
miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway.
Frontiers in genetics
Luo H,Peng F,Weng B,Tang X,Chen Y,Yang A,Chen B,Ran M
Fri Dec 18 00:00:00 EST 2020
DEF Cell-Derived Exosomal miR-148a-5p Promotes DTMUV Replication by Negative Regulating TLR3 Expression.
Viruses
Guo H,Cheng A,Zhang X,Pan Y,Wang M,Huang J,Zhu D,Chen S,Liu M,Zhao X,Wu Y,Yang Q,Zhang S,Yu Y,Pan L,Tian B,Rehman MU,Chen X,Liu Y,Zhang L,Yin Z,Jing B,Jia R
Tue Jan 14 00:00:00 EST 2020
Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition.
Steroids
Xu W,Chen S,Wang X,Wu H,Yamada H,Hirano T
Sun Nov 01 00:00:00 EDT 2020
Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning.
Molecular medicine reports
Li J,Zhou W,Chen W,Wang H,Zhang Y,Yu T
Sun Mar 01 00:00:00 EST 2020
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
Evidence-based complementary and alternative medicine : eCAM
Xu Q,Yang S,Wu F,Lin Y,Zhong J,Tang L,Hu X,Cai J
Thu Oct 22 00:00:00 EDT 2020
iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Brain research
Xie K,Lian N,Kan Y,Yang M,Pan J,Yu Y,Yu Y
Sun Nov 01 00:00:00 EDT 2020
Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels.
Evidence-based complementary and alternative medicine : eCAM
Wang YQ,Liao Q,Tang SH,Cai Z,Zhang HC
Wed Apr 13 00:00:00 EDT 2022
Exploring the mechanism of cisplatin resistance by transcriptome sequencing and reversing the chemoresistance by autophagy inhibition in small cell lung cancer.
Biochemical and biophysical research communications
Ma K,Li S,Huo X,Guo M,Du X,Li C,Liu X,Lv J,Chen Z
Thu Dec 10 00:00:00 EST 2020
Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis.
International immunopharmacology
Li X,Zou F,Lu Y,Fan X,Wu Y,Feng X,Sun X,Liu Y
Sun Nov 01 00:00:00 EDT 2020
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
Biomaterials
Lu L,Qi S,Chen Y,Luo H,Huang S,Yu X,Luo Q,Zhang Z
Wed Jul 01 00:00:00 EDT 2020
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lu H,Chen W,Liu W,Si Y,Zhao T,Lai X,Kang Z,Sun X,Guo Z
Sun Mar 01 00:00:00 EST 2020
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Molecular oncology
Zhang X,Bai J,Yin H,Long L,Zheng Z,Wang Q,Chen F,Yu X,Zhou Y
Thu Oct 01 00:00:00 EDT 2020
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
Theranostics
Meng Q,Liang C,Hua J,Zhang B,Liu J,Zhang Y,Wei M,Yu X,Xu J,Shi S
Tue May 18 00:00:00 EDT 2021
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Aging
Sun T,Bi F,Liu Z,Yang Q
Thu Jul 09 00:00:00 EDT 2020
c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.
Nature communications
Feng YC,Liu XY,Teng L,Ji Q,Wu Y,Li JM,Gao W,Zhang YY,La T,Tabatabaee H,Yan XG,Jamaluddin MFB,Zhang D,Guo ST,Scott RJ,Liu T,Thorne RF,Zhang XD,Jin L
Mon Oct 05 00:00:00 EDT 2020
Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat.
Frontiers in pharmacology
Li T,Hu E,Li P,Yang Z,Wu Y,Ding R,Zhu X,Tang T,Wang Y
Wed Oct 28 00:00:00 EDT 2020
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
Cell death & disease
Yang X,Chen G,Yu KN,Yang M,Peng S,Ma J,Qin F,Cao W,Cui S,Nie L,Han W
Mon Apr 27 00:00:00 EDT 2020
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Cell
Zheng M,Karki R,Vogel P,Kanneganti TD
Thu Apr 30 00:00:00 EDT 2020
Sublethal Levels of Antibiotics Promote Bacterial Persistence in Epithelial Cells.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu X,Liu F,Ding S,Shen J,Zhu K
Tue Sep 01 00:00:00 EDT 2020
p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.
Nature communications
Deng L,Yao P,Li L,Ji F,Zhao S,Xu C,Lan X,Jiang P
Thu Apr 09 00:00:00 EDT 2020
Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice.
Molecular and cellular biochemistry
Liu Y,Che G,Di Z,Sun W,Tian J,Ren M
Wed Jan 01 00:00:00 EST 2020
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Pharmacological research
Zhu Y,Zhu C,Yang H,Deng J,Fan D
Fri May 01 00:00:00 EDT 2020
Spatiotemporal heterogeneity of PPARγ expression in porcine uteroplacenta for regulating of placental angiogenesis through VEGF-mediated signalling.
Reproduction in domestic animals = Zuchthygiene
Zhang J,Xue L,Nie A,Yang Q,Peng X,Chen Z,Yang L,Xie Y,Yuan A,Xu J
Sun Nov 01 00:00:00 EDT 2020
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Cancer management and research
Yu W,Xiang D,Jia H,He X,Sheng J,Long Y,Zhu S,Wang K,Liu Q
Wed Apr 13 00:00:00 EDT 2022
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Molecular medicine reports
Yao Y
Sun Mar 01 00:00:00 EST 2020
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Marine drugs
Li Y,Ye H,Wang T,Wang P,Liu R,Li Y,Tian Y,Zhang J
Tue Sep 29 00:00:00 EDT 2020
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Journal of medicinal chemistry
Shi X,Zhang T,Lou H,Song H,Li C,Fan P
Thu Oct 22 00:00:00 EDT 2020
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Molecular and cellular probes
Zhao L,Li R,Qiu JZ,Yu JB,Cao Y,Yuan RT
Thu Oct 01 00:00:00 EDT 2020
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease.
Basic & clinical pharmacology & toxicology
Alarcón-Sánchez BR,Guerrero-Escalera D,Rosas-Madrigal S,Ivette Aparicio-Bautista D,Reyes-Gordillo K,Lakshman MR,Ortiz-Fernández A,Quezada H,Medina-Contreras Ó,Villa-Treviño S,Isael Pérez-Carreón J,Arellanes-Robledo J
Sun Nov 01 00:00:00 EDT 2020
Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Genes
Fan Y,Han Z,Lu X,Zhang H,Arbab AAI,Loor JJ,Yang Y,Yang Z
Mon Nov 16 00:00:00 EST 2020
High Expression of c-Met, PKCλ and ALDH1A3 Predicts a Poor Prognosis in Late-stage Breast Cancer.
Anticancer research
Motomura H,Nozaki Y,Onaga C,Ozaki A,Tamori S,Shiina TA,Kanai S,Ohira C,Hara Y,Harada Y,Takasawa R,Hanawa T,Tanuma SI,Mano Y,Sato T,Sato K,Akimoto K
Wed Jan 01 00:00:00 EST 2020
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Molecular cancer therapeutics
Wang Q,Jia S,Wang D,Chen X,Kalvakolanu DV,Zheng H,Wei X,Wen N,Liang H,Guo B,Zhang L
Tue Dec 01 00:00:00 EST 2020
Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
International journal of molecular sciences
Liu WC,Shyu JF,Lim PS,Fang TC,Lu CL,Zheng CM,Hou YC,Wu CC,Lin YF,Lu KC
Fri May 15 00:00:00 EDT 2020
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Bioscience reports
Wang H,Wei Z,Li H,Guan Y,Han Z,Wang H,Liu B
Fri Jun 26 00:00:00 EDT 2020
Long Noncoding RNA DSCAM-AS1 Facilitates Colorectal Cancer Cell Proliferation and Migration via miR-137/Notch1 Axis.
Journal of Cancer
Xu J,Wu G,Zhao Y,Han Y,Zhang S,Li C,Zhang J
Fri Oct 16 00:00:00 EDT 2020
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Life sciences
Wang B,Xu H,Hu X,Ma W,Zhang J,Li Y,Yu M,Zhang Y,Li X,Ye X
Sun Mar 15 00:00:00 EDT 2020
Human mesenchymal stem cells-derived conditioned medium inhibits hypoxia-induced death of neonatal porcine islets by inducing autophagy.
Xenotransplantation
Xu Y,Tan M,Ma X,Li H,He X,Chen Z,Tan Y,Nie W,Rong P,Wang W
Wed Jan 01 00:00:00 EST 2020
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis.
Journal of applied toxicology : JAT
Zhang Z,Zhu W,Liu Z,Liu Y,Chang C,Jiang H,Li R,Xiao Y,Chen W,Hu Q,Wang Q
Tue Dec 01 00:00:00 EST 2020
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Biomolecules
Wang YS,Li H,Li Y,Zhang S,Jin YH
Tue Mar 31 00:00:00 EDT 2020
Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A.
BioMed research international
Sun K,Tian W,Li X,Liu W,Yang Y,Zhu X
Tue Mar 30 00:00:00 EDT 2021
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Biochemical and biophysical research communications
Fang Y,Li F,Qi C,Mao X,Xu Y,Zhao Z,Wu H,Zhang Z
Thu Aug 13 00:00:00 EDT 2020
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo.
EJNMMI research
Zhao S,Pan W,Jiang H,Zhang R,Jiang H,Liang Z,Hu H
Mon Jun 15 00:00:00 EDT 2020
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Watanabe K,Nakamura T,Onodera S,Saito A,Shibahara T,Azuma T
Tue Sep 01 00:00:00 EDT 2020
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Nutrition & metabolism
Wang J,Zhang Y,Zhuo Q,Tseng Y,Wang J,Ma Y,Zhang J,Liu J
Sat Nov 11 00:00:00 EST 2023
A mitophagic response to iron overload-induced oxidative damage associated with the PINK1/Parkin pathway in pancreatic beta cells.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
Zhang L,Hou L,Liu Z,Huang S,Meng Z,Liang L
Wed Jul 01 00:00:00 EDT 2020
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Animals : an open access journal from MDPI
Ma S,Wang L,Zong B,Wang Y,Wang X,Shi Y,Yang Y,Chen Y
Wed Aug 12 00:00:00 EDT 2020
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
American journal of physiology. Renal physiology
Liu S,Yang Y,Gao H,Zhou N,Wang P,Zhang Y,Zhang A,Jia Z,Huang S
Wed Apr 01 00:00:00 EDT 2020
β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways.
OncoTargets and therapy
Su P,Ahmad B,Zou K,Zou L
Fri Apr 15 00:00:00 EDT 2022
Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Sun Y,Zhao W,Ma Y,Yan Z,Nie X
Fri May 01 00:00:00 EDT 2020
Mitochondrial dysfunction is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells.
Human & experimental toxicology
Liu X,Wu J,Wang J,Feng X,Wu H,Huang R,Fan J,Yu X,Yang X
Fri May 01 00:00:00 EDT 2020
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats.
Journal of molecular histology
Yang Z,Jia H,Bai Y,Wang W
Thu Oct 01 00:00:00 EDT 2020
Mycoplasma bovis-generated reactive oxygen species and induced apoptosis in bovine mammary epithelial cell cultures.
Journal of dairy science
Liu Y,Zhou M,Xu S,Khan MA,Shi Y,Qu W,Gao J,Liu G,Kastelic JP,Han B
Sun Nov 01 00:00:00 EDT 2020
Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.
World journal of gastroenterology
Lu QG,Zeng L,Li XH,Liu Y,Du XF,Bai GM,Yan X
Sat Mar 21 00:00:00 EDT 2020
Effect of miR-195-5p on cardiomyocyte apoptosis in rats with heart failure by regulating TGF-β1/Smad3 signaling pathway.
Bioscience reports
Xie C,Qi H,Huan L,Yang Y
Fri May 29 00:00:00 EDT 2020
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Chemosphere
Wang HW,Liu J,Wei SS,Zhao WP,Zhu SQ,Zhou BH
Sat Feb 01 00:00:00 EST 2020
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Medical science monitor : international medical journal of experimental and clinical research
Li M,Wang J,Fu L,Lu Y,Xu J,Zhou L,Zhu H,Fang L,Feng Z,Xie T,Zhou X
Sat Feb 15 00:00:00 EST 2020
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Planta medica
Han B,Jiang L,Jiang P,Zhou D,Jia X,Li X,Ye X
Wed Jul 01 00:00:00 EDT 2020
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Cell biology international
Hu J,Lu X,Zhang X,Shao X,Wang Y,Chen J,Zhao B,Li S,Xu C,Wei C
Sat Aug 01 00:00:00 EDT 2020
MicroRNA-362-3p Inhibits Migration and Invasion via Targeting BCAP31 in Cervical Cancer.
Frontiers in molecular biosciences
Yang S,Zhang X,Sun Y,Shi J,Jiang D,Wang J,Liu Y,Hu C,Pan J,Zheng L,Yang K
Mon Sep 28 00:00:00 EDT 2020
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
International immunopharmacology
Qian G,Zhu L,Huang C,Liu Y,Ren Y,Ding Y,Qian W,Xu Q,Zheng H,Lv H
Thu Oct 01 00:00:00 EDT 2020
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Journal of cellular and molecular medicine
Li T,Hu SM,Pang XY,Wang JF,Yin JY,Li FH,Wang J,Yang XQ,Xia B,Liu YH,Song WG,Guo SD
Sun Mar 01 00:00:00 EST 2020
PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway.
Journal of veterinary science
Li M,Wei X,Li Y,Feng T,Jiang L,Zhu H,Yu X,Tang J,Chen G,Zhang J,Zhang X
Fri May 01 00:00:00 EDT 2020
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model.
Respiratory research
Zeng H,Li T,He X,Cai S,Luo H,Chen P,Chen Y
Thu Sep 03 00:00:00 EDT 2020
Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats.
Frontiers in neuroscience
Lei L,Wu X,Gu H,Ji M,Yang J
Tue Nov 17 00:00:00 EST 2020
IL-29 promoted obesity-induced inflammation and insulin resistance.
Cellular & molecular immunology
Lin TY,Chiu CJ,Kuan CH,Chen FH,Shen YC,Wu CH,Hsu YH
Wed Apr 01 00:00:00 EDT 2020
Brequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
American journal of translational research
Fu H,Zhang Z,Dai Y,Liu S,Fu E
Thu Jan 14 00:00:00 EST 2021
MiR-129-5p protects against myocardial ischemia-reperfusion injury via targeting HMGB1.
European review for medical and pharmacological sciences
Chen ZX,He D,Mo QW,Xie LP,Liang JR,Liu L,Fu WJ
Wed Apr 01 00:00:00 EDT 2020
MiR-1307-5p targeting TRAF3 upregulates the MAPK/NF-κB pathway and promotes lung adenocarcinoma proliferation.
Cancer cell international
Du X,Wang S,Liu X,He T,Lin X,Wu S,Wang D,Li J,Huang W,Yang H
Sun Apr 17 00:00:00 EDT 2022
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Brain research bulletin
Liu Y,Wen D,Gao J,Xie B,Yu H,Shen Q,Zhang J,Jing W,Cong B,Ma C
Tue Sep 01 00:00:00 EDT 2020
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Journal of cellular and molecular medicine
Zhang S,Wang H,Liu Y,Yang W,Liu J,Han Y,Liu Y,Liu F,Sun L,Xiao L
Tue Sep 01 00:00:00 EDT 2020
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Inflammation
Luo Y,Pang XX,Ansari AR,Wu XT,Li HZ,Zhang ZW,Song H
Sat Feb 01 00:00:00 EST 2020
Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway.
Frontiers in oncology
Yang M,Wang A,Li C,Sun J,Yi G,Cheng H,Liu X,Wang Z,Zhou Y,Yao G,Wang S,Liang R,Li B,Li D,Zhao H
Mon Sep 28 00:00:00 EDT 2020
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
Liu R,Hong R,Wang Y,Gong Y,Yeerken D,Yang D,Li J,Fan J,Chen J,Zhang W,Zhan Q
Sat Oct 31 00:00:00 EDT 2020
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
Journal of cell science
Hosseini ES,Nikkhah M,Hamidieh AA,Fearnhead HO,Concordet JP,Hosseinkhani S
Wed May 27 00:00:00 EDT 2020
DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.
Journal of neuroinflammation
Peng L,Zhou Y,Jiang N,Wang T,Zhu J,Chen Y,Li L,Zhang J,Yu S,Zhao Y
Mon Mar 09 00:00:00 EDT 2020
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Life sciences
Cheng J,Zhang Y,Ge Y,Li W,Cao Y,Qu Y,Liu S,Guo Y,Fu S,Liu J
Thu Oct 15 00:00:00 EDT 2020
Proteomic analyses reveal that Orf virus induces the activation and maturation of mouse bone marrow-derived dendritic cells.
Research in veterinary science
Feng Q,Li L,Du G,Liu Y,Liu X,Wu J,Shang Y
Thu Oct 01 00:00:00 EDT 2020
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Cell communication and signaling : CCS
Ayanlaja AA,Ji G,Wang J,Gao Y,Cheng B,Kanwore K,Zhang L,Xiong Y,Kambey PA,Gao D
Wed Feb 12 00:00:00 EST 2020
BMP7 is Downregulated in Lumbosacral Spinal Cord of Rat Embryos With Anorectal Malformation.
The Journal of surgical research
Yang Z,Li X,Jia H,Bai Y,Wang W
Wed Jul 01 00:00:00 EDT 2020
L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Aging
Zeng Z,Gong X,Hu Z
Sun Jun 21 00:00:00 EDT 2020
Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang D,Luo Z,Jin Y,Chen Y,Yang T,Yang Q,Wu B,Shang Y,Liu X,Wei Y,Zhou F
Mon Sep 13 00:00:00 EDT 2021
NLRC3 Delays the Progression of AD in APP/PS1 Mice via Inhibiting PI3K Activation.
Oxidative medicine and cellular longevity
Zha L,Yu Z,Fang J,Zhou L,Guo W,Zhou J
Mon Sep 13 00:00:00 EDT 2021
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Biochemical and biophysical research communications
Wu J,Lu K,Zhu M,Xie X,Ding Y,Shao X,Chen Y,Liu J,Xu M,Xu Y,Zhou J,Shen X,Zhu C
Wed Jan 22 00:00:00 EST 2020
Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress.
Biological & pharmaceutical bulletin
Cheng L,Yang Z,Sun Z,Zhang W,Ren Y,Wang M,Han X,Fei L,Zhao Y,Pan H,Xie J,Nie S
Wed Jan 01 00:00:00 EST 2020
HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6.
International journal of molecular sciences
D'Ignazio L,Shakir D,Batie M,Muller HA,Rocha S
Fri Apr 24 00:00:00 EDT 2020
Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway.
Life sciences
Zhu Y,Liu R,Shen Z,Cai G
Tue Sep 01 00:00:00 EDT 2020
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Journal of hazardous materials
Liang C,Feng Z,Manthari RK,Wang C,Han Y,Fu W,Wang J,Zhang J
Fri Jun 05 00:00:00 EDT 2020
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
Cellular & molecular immunology
Du X,Wu Z,Xu Y,Liu Y,Liu W,Wang T,Li C,Zhang C,Yi F,Gao L,Liang X,Ma C
Fri Nov 01 00:00:00 EDT 2019
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
Cellular & molecular immunology
Du X,Wu Z,Xu Y,Liu Y,Liu W,Wang T,Li C,Zhang C,Yi F,Gao L,Liang X,Ma C
Fri Nov 01 00:00:00 EDT 2019
CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock.
EMBO reports
Carrieri FA,Murray PJ,Ditsova D,Ferris MA,Davies P,Dale JK
Mon Jul 01 00:00:00 EDT 2019
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions.
Oncogene
Marcus J,Bejerano-Sagie M,Patterson N,Bagchi S,Verkhusha VV,Connolly D,Goldberg GL,Golden A,Sharma VP,Condeelis J,Montagna C
Mon Jul 01 00:00:00 EDT 2019
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Acta pharmacologica Sinica
Jiang SL,Guan YD,Chen XS,Ge P,Wang XL,Lao YZ,Xiao SS,Zhang Y,Yang JM,Xu XJ,Cao DS,Cheng Y
Mon Jul 01 00:00:00 EDT 2019
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.
Acta pharmacologica Sinica
Jiang SL,Guan YD,Chen XS,Ge P,Wang XL,Lao YZ,Xiao SS,Zhang Y,Yang JM,Xu XJ,Cao DS,Cheng Y
Mon Jul 01 00:00:00 EDT 2019
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
Journal of virology
Yao Y,Yang B,Chen Y,Wang H,Hu X,Zhou Y,Gao X,Lu M,Niu J,Wen Z,Wu C,Chen X
Fri Mar 15 00:00:00 EDT 2019
RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
Journal of virology
Yao Y,Yang B,Chen Y,Wang H,Hu X,Zhou Y,Gao X,Lu M,Niu J,Wen Z,Wu C,Chen X
Fri Mar 15 00:00:00 EDT 2019
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
Journal of cellular physiology
Tan Z,Kang T,Zhang X,Tong Y,Chen S
Mon Apr 01 00:00:00 EDT 2019
Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway.
Journal of cellular physiology
Tan Z,Kang T,Zhang X,Tong Y,Chen S
Mon Apr 01 00:00:00 EDT 2019
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Journal of cellular physiology
Chen H,Shan J,Chen D,Wang R,Qi W,Wang H,Ke Y,Liu W,Zeng X
Mon Jul 01 00:00:00 EDT 2019
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Journal of cellular physiology
Chen H,Shan J,Chen D,Wang R,Qi W,Wang H,Ke Y,Liu W,Zeng X
Mon Jul 01 00:00:00 EDT 2019
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
Phytotherapy research : PTR
Xu W,Wang X,Tu Y,Masaki H,Tanaka S,Onda K,Sugiyama K,Yamada H,Hirano T
Tue Jan 01 00:00:00 EST 2019
Plant-derived alkaloid sinomenine potentiates glucocorticoid pharmacodynamics in mitogen-activated human peripheral blood mononuclear cells by regulating the translocation of glucocorticoid receptor.
Phytotherapy research : PTR
Xu W,Wang X,Tu Y,Masaki H,Tanaka S,Onda K,Sugiyama K,Yamada H,Hirano T
Tue Jan 01 00:00:00 EST 2019
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
International journal of oncology
Wang S,Gao P,Li N,Chen P,Wang J,He N,Ji K,Du L,Liu Q
Tue Jan 01 00:00:00 EST 2019
Autocrine secretions enhance radioresistance in an exosome‑independent manner in NSCLC cells.
International journal of oncology
Wang S,Gao P,Li N,Chen P,Wang J,He N,Ji K,Du L,Liu Q
Tue Jan 01 00:00:00 EST 2019
Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1.
International journal of oncology
Bu S,Li B,Wang Q,Gu T,Dong Q,Miao X,Lai D
Mon Jul 01 00:00:00 EDT 2019
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Gu Y,Cai R,Zhang C,Xue Y,Pan Y,Wang J,Zhang Z
Tue Jan 01 00:00:00 EST 2019
miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Gu Y,Cai R,Zhang C,Xue Y,Pan Y,Wang J,Zhang Z
Tue Jan 01 00:00:00 EST 2019
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang X,Ding Y,Lin F,Zhang Y,Zhou X,Meng Q,Lu X,Jiang G,Zhu H,Chen Y,Lian Q,Fan H,Liu Z
Fri Mar 01 00:00:00 EST 2019
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Molecular neurobiology
Guo Y,Li H,Ke X,Deng M,Wu Z,Cai Y,Afewerky HK,Zhang X,Pei L,Lu Y
Wed May 01 00:00:00 EDT 2019
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging.
Molecular neurobiology
Guo Y,Li H,Ke X,Deng M,Wu Z,Cai Y,Afewerky HK,Zhang X,Pei L,Lu Y
Wed May 01 00:00:00 EDT 2019
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Journal of cellular biochemistry
Wu X,Pan B,Liu L,Zhao W,Zhu J,Huang X,Tian J
Fri Mar 01 00:00:00 EST 2019
In utero exposure to PM2.5 during gestation caused adult cardiac hypertrophy through histone acetylation modification.
Journal of cellular biochemistry
Wu X,Pan B,Liu L,Zhao W,Zhu J,Huang X,Tian J
Fri Mar 01 00:00:00 EST 2019
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Journal of cellular biochemistry
Cao S,Xu P,Yan J,Liu H,Liu L,Cheng L,Qiu F,Kang N
Fri Feb 01 00:00:00 EST 2019
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Journal of cellular biochemistry
Cao S,Xu P,Yan J,Liu H,Liu L,Cheng L,Qiu F,Kang N
Fri Feb 01 00:00:00 EST 2019
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Oncology reports
Guo W,Li H,Liu H,Ma X,Yang S,Wang Z
Sun Sep 01 00:00:00 EDT 2019
GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin.
Molecular biology of the cell
Ahat E,Xiang Y,Zhang X,Bekier ME,Wang Y
Fri Mar 15 00:00:00 EDT 2019
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Brain research
Yuan Q,Jia HX,Li SQ,Wu YJ,Feng L,Liu XL,Sun XC,Li WB
Fri Mar 15 00:00:00 EDT 2019
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Brain research
Yuan Q,Jia HX,Li SQ,Wu YJ,Feng L,Liu XL,Sun XC,Li WB
Fri Mar 15 00:00:00 EDT 2019
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Molecular medicine reports
Wang Q,Sun Y,Li T,Liu L,Zhao Y,Li L,Zhang L,Meng Y
Tue Jan 01 00:00:00 EST 2019
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Molecular medicine reports
Wang Q,Sun Y,Li T,Liu L,Zhao Y,Li L,Zhang L,Meng Y
Tue Jan 01 00:00:00 EST 2019
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Reproductive toxicology (Elmsford, N.Y.)
Hu L,Peng T,Huang J,Su T,Luo R,Zheng Y,Zhong Z,Yu P,Nie K,Zheng L
Tue Jan 01 00:00:00 EST 2019
Tri-ortho-cresyl phosphate (TOCP) induced ovarian failure in mice is related to the Hippo signaling pathway disruption.
Reproductive toxicology (Elmsford, N.Y.)
Hu L,Peng T,Huang J,Su T,Luo R,Zheng Y,Zhong Z,Yu P,Nie K,Zheng L
Tue Jan 01 00:00:00 EST 2019
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Neuroscience letters
Yin WL,Yin WG,Huang BS,Wu LX
Fri Jan 18 00:00:00 EST 2019
LncRNA SNHG12 inhibits miR-199a to upregulate SIRT1 to attenuate cerebral ischemia/reperfusion injury through activating AMPK signaling pathway.
Neuroscience letters
Yin WL,Yin WG,Huang BS,Wu LX
Fri Jan 18 00:00:00 EST 2019
Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men.
Systems biology in reproductive medicine
Mousavi MS,Shahverdi A,Drevet J,Akbarinejad V,Esmaeili V,Sayahpour FA,Topraggaleh TR,Rahimizadeh P,Alizadeh A
Sun Dec 01 00:00:00 EST 2019
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Nutrition and cancer
Wang J,Shao L,Wang CZ,Zhou HH,Yuan CS,Huang WH
Fri May 01 00:00:00 EDT 2020
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Nutrition and cancer
Wang J,Shao L,Wang CZ,Zhou HH,Yuan CS,Huang WH
Fri May 01 00:00:00 EDT 2020
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhu H,Dai R,Fu H,Meng Q
Tue Jan 01 00:00:00 EST 2019
MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen-Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhu H,Dai R,Fu H,Meng Q
Tue Jan 01 00:00:00 EST 2019
Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens.
Antioxidants (Basel, Switzerland)
Jiang J,Qi L,Lv Z,Jin S,Wei X,Shi F
Thu Nov 21 00:00:00 EST 2019
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society
Steinbichler TB,Savic D,Dejaco D,Romani A,Kofler B,Skvortsova II,Riechelmann H,Dudas J
Sun Dec 01 00:00:00 EST 2019
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Cancer management and research
Zhang Q,Zhao X,Zhang C,Wang W,Li F,Liu D,Wu K,Zhu D,Liu S,Shen C,Yuan X,Zhang K,Yang Y,Zhang Y,Zhao S
Mon Apr 11 00:00:00 EDT 2022
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
ACS applied materials & interfaces
Shang Y,Wang Q,Wu B,Zhao Q,Li J,Huang X,Chen W,Gui R
Wed Aug 07 00:00:00 EDT 2019
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Journal of agricultural and food chemistry
Yang Y,Sun Q,Xu X,Yang X,Gao Y,Sun X,Zhao Y,Ding Z,Ge W,Cheng R,Zhang J
Wed Dec 04 00:00:00 EST 2019
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Journal of diabetes
Jin J,Gong J,Zhao L,Zhang H,He Q,Jiang X
Tue Oct 01 00:00:00 EDT 2019
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
iScience
Zhao J,Han Y,Ma X,Zhou Y,Yuan S,Shen Q,Ye G,Liu H,Fu P,Zhang G,Qiao B,Liu A
Fri Mar 29 00:00:00 EDT 2019
Treatment With Liraglutide Exerts Neuroprotection After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway.
Frontiers in cellular neuroscience
Zeng SS,Bai JJ,Jiang H,Zhu JJ,Fu CC,He MZ,Zhu JH,Chen SQ,Li PJ,Fu XQ,Lin ZL
Mon Sep 28 00:00:00 EDT 2020
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
International immunopharmacology
Lyu Z,Ji X,Chen G,An B
Mon Jul 01 00:00:00 EDT 2019
Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR.
Mediators of inflammation
Leng B,Zhang Y,Liu X,Zhang Z,Liu Y,Wang H,Lu M
Mon Jul 22 00:00:00 EDT 2019
Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
Cell reports
Simon CM,Van Alstyne M,Lotti F,Bianchetti E,Tisdale S,Watterson DM,Mentis GZ,Pellizzoni L
Tue Dec 17 00:00:00 EST 2019
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation.
Life sciences
Nie Q,Zhu L,Zhang L,Leng B,Wang H
Sun Sep 01 00:00:00 EDT 2019
SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy.
The Journal of endocrinology
Han W,Wang C,Yang Z,Mu L,Wu M,Chen N,Du C,Duan H,Shi Y
Fri Feb 01 00:00:00 EST 2019
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Chemico-biological interactions
Xu W,Wang X,Tu Y,Masaki H,Tanaka S,Onda K,Sugiyama K,Yamada H,Hirano T
Sun Sep 01 00:00:00 EDT 2019
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Oxidative medicine and cellular longevity
Liu P,Li Y,Yang W,Liu D,Ji X,Chi T,Guo Z,Li L,Zou L
Wed Aug 28 00:00:00 EDT 2019
MIF/CD74 axis participates in inflammatory activation of Schwann cells following sciatic nerve injury.
Journal of molecular histology
Song H,Zhu Z,Zhou Y,Du N,Song T,Liang H,Chen X,Wang Y,Wang Y,Hu Y
Thu Aug 01 00:00:00 EDT 2019
Screening candidate microR-15a- IRAK2 regulatory pairs for predicting the response to Staphylococcus aureus-induced mastitis in dairy cows.
The Journal of dairy research
Chen Z,Zhou J,Wang X,Zhang Y,Lu X,Fan Y,Mao Y,Loor JJ,Yang Z
Fri Nov 01 00:00:00 EDT 2019
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Journal of experimental & clinical cancer research : CR
Li Z,Chen Y,An T,Liu P,Zhu J,Yang H,Zhang W,Dong T,Jiang J,Zhang Y,Jiang M,Yang X
Fri Mar 29 00:00:00 EDT 2019
Adipose HuR protects against diet-induced obesity and insulin resistance.
Nature communications
Li J,Gong L,Liu S,Zhang Y,Zhang C,Tian M,Lu H,Bu P,Yang J,Ouyang C,Jiang X,Wu J,Zhang Y,Min Q,Zhang C,Zhang W
Thu May 30 00:00:00 EDT 2019
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Boureima Oumarou D,Ji H,Xu J,Li S,Ruan W,Xiao F,Yu F
Thu Aug 01 00:00:00 EDT 2019
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li S,Zhou J,Xu S,Li J,Liu J,Lu Y,Shi J,Zhou S,Wu Q
Sun Sep 01 00:00:00 EDT 2019
LncRNA TPT1-AS1 promotes tumorigenesis and metastasis in epithelial ovarian cancer by inducing TPT1 expression.
Cancer science
Wu W,Gao H,Li X,Zhu Y,Peng S,Yu J,Zhan G,Wang J,Liu N,Guo X
Wed May 01 00:00:00 EDT 2019
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Journal of animal science and biotechnology
Kang K,Huang L,Li Q,Liao X,Dang Q,Yang Y,Luo J,Zeng Y,Li L,Gou D
Fri Apr 08 00:00:00 EDT 2022
Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.
Aging
Pan CH,Chen CJ,Shih CM,Wang MF,Wang JY,Wu CH
Thu Oct 03 00:00:00 EDT 2019
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Cell proliferation
Sheng J,Shen L,Sun L,Zhang X,Cui R,Wang L
Wed May 01 00:00:00 EDT 2019
Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.
Scientific reports
Liu X,Ouyang T,Ouyang H,Liu X,Niu G,Huo W,Yin W,Pang D,Ren L
Thu Apr 04 00:00:00 EDT 2019
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Plant foods for human nutrition (Dordrecht, Netherlands)
Dia VP,Bradwell J,Pangloli P
Sun Sep 01 00:00:00 EDT 2019
Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway.
Frontiers in cellular neuroscience
Liang YX,Wang NN,Zhang ZY,Juan ZD,Zhang C
Thu Oct 01 00:00:00 EDT 2020
Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gao L,Sang JZ,Cao H
Tue Oct 01 00:00:00 EDT 2019
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
World journal of gastroenterology
Yang JM,Sun Y,Wang M,Zhang XL,Zhang SJ,Gao YS,Chen L,Wu MY,Zhou L,Zhou YM,Wang Y,Zheng FJ,Li YH
Sat Sep 14 00:00:00 EDT 2019
5-aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells.
Journal of photochemistry and photobiology. B, Biology
Xie J,Wang S,Li Z,Ao C,Wang J,Wang L,Peng X,Zeng K
Wed May 01 00:00:00 EDT 2019
Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.
Protein & cell
Ge Y,Wu S,Zhang Z,Li X,Li F,Yan S,Liu H,Huang J,Zhao Y
Fri Nov 01 00:00:00 EDT 2019
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Journal of food science
Chai XX,Le YF,Wang JC,Mei CX,Feng JF,Zhao H,Wang C,Lu DZ
Sun Dec 01 00:00:00 EST 2019
An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection.
Frontiers in pharmacology
Ye C,Wang D,Liu H,Ma H,Dong Y,Yao M,Wang Y,Zhang H,Zhang L,Cheng L,Xu Z,Lei Y,Zhang F,Ye W
Mon Sep 28 00:00:00 EDT 2020
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
Laboratory investigation; a journal of technical methods and pathology
Liu Q,Xie W,Wang Y,Chen S,Han J,Wang L,Gui P,Wu Q
Sun Dec 01 00:00:00 EST 2019
Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field.
Biotechnology progress
Huang CH,Lei KF,Tsang NM
Wed May 01 00:00:00 EDT 2019
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Brain : a journal of neurology
Zhu BL,Long Y,Luo W,Yan Z,Lai YJ,Zhao LG,Zhou WH,Wang YJ,Shen LL,Liu L,Deng XJ,Wang XF,Sun F,Chen GJ
Tue Jan 01 00:00:00 EST 2019
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.
Journal of cellular and molecular medicine
Guan Y,Gao X,Tang Q,Huang L,Gao S,Yu S,Huang J,Li J,Zhou D,Zhang Y,Shi D,Liang D,Liu Y,Li L,Cui Y,Xu L,Chen YH
Fri Feb 01 00:00:00 EST 2019
Evidence for interaction of the NLRP3 inflammasome and Bruton's tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta.
Oncoimmunology
Benner B,Scarberry L,Stiff A,Duggan MC,Good L,Lapurga G,Butchar JP,Tridandapani S,Carson WE
Sat Oct 14 00:00:00 EDT 2023
PM2.5 upregulates rat mesenteric arteries 5-HT2A receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
Environmental toxicology
Wang R,Cao L,Shen ZX,Cao YX,Yu J
Tue Oct 01 00:00:00 EDT 2019
Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
BioMed research international
Sun C,Wang Y,Mo M,Song C,Wang X,Chen S,Liu Y
Mon Jul 22 00:00:00 EDT 2019
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Journal of cellular and molecular medicine
Fan X,Zhao Y
Sun Dec 01 00:00:00 EST 2019
Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.
Viruses
Ouyang T,Niu G,Zhang Y,Liu X,Zhang X,Zhang S,Geng Y,Pang D,Ouyang H,Ren L
Tue Jun 11 00:00:00 EDT 2019
The fucoidan from the brown seaweed Ascophyllum nodosum ameliorates atherosclerosis in apolipoprotein E-deficient mice.
Food & function
Yin J,Wang J,Li F,Yang Z,Yang X,Sun W,Xia B,Li T,Song W,Guo S
Thu Aug 01 00:00:00 EDT 2019
ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation.
Frontiers in pharmacology
Yang GM,Yan K,Wang P,Zhang JL,Pan ZH,Pan Y
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Cell proliferation
Tian F,Yu C,Wu M,Wu X,Wan L,Zhu X
Sun Sep 01 00:00:00 EDT 2019
Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway.
Biological & pharmaceutical bulletin
Deng X,Sheng J,Liu H,Wang N,Dai C,Wang Z,Zhang J,Zhao J,Dai E
Mon Jan 27 00:00:00 EST 2020
Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
Frontiers in microbiology
Pan P,Zhang Q,Liu W,Wang W,Yu Z,Lao Z,Zhang W,Shen M,Wan P,Xiao F,Shereen MA,Zhang W,Tan Q,Liu Y,Liu X,Wu K,Liu Y,Li G,Wu J
Thu Oct 01 00:00:00 EDT 2020
Heat shock factor 1 in cancer-associated fibroblasts is a potential prognostic factor and drives progression of oral squamous cell carcinoma.
Cancer science
Wang Q,Zhang YC,Zhu LF,Pan L,Yu M,Shen WL,Li B,Zhang W,Liu LK
Wed May 01 00:00:00 EDT 2019
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
The Journal of biological chemistry
Yang X,Wang G,Cao T,Zhang L,Ma Y,Jiang S,Teng X,Sun X
Fri Aug 30 00:00:00 EDT 2019
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
European journal of pharmacology
Yanchun M,Yi W,Lu W,Yu Q,Jian Y,Pengzhou K,Ting Y,Hongyi L,Fang W,Xiaolong C,Yongping C
Wed May 15 00:00:00 EDT 2019
Functional evidence for a de novo mutation in WDR45 leading to BPAN in a Chinese girl.
Molecular genetics & genomic medicine
Xiong Q,Li W,Li P,Zhao Z,Wu C,Xiao H
Sun Sep 01 00:00:00 EDT 2019
Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome.
Frontiers in microbiology
Xin S,Du S,Liu L,Xie Y,Zuo L,Yang J,Hu J,Yue W,Zhang J,Cao P,Zhu F,Lu J
Thu Oct 01 00:00:00 EDT 2020
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
OncoTargets and therapy
Yu X,Li Z,Zhang Y,Xu M,Che Y,Tian X,Wang R,Zou K,Zou L
Tue Sep 29 00:00:00 EDT 2020
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Journal of experimental & clinical cancer research : CR
Zong ZH,Du YP,Guan X,Chen S,Zhao Y
Wed Oct 30 00:00:00 EDT 2019
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H2O2-induced apoptosis in rat intervertebral disc cells.
The Journal of steroid biochemistry and molecular biology
Tong T,Liu Z,Zhang H,Sun J,Zhang D,Wang F,Miao D,Shen Y
Sat Jun 01 00:00:00 EDT 2019
Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice.
Journal of virology
Pan P,Zhang Q,Liu W,Wang W,Lao Z,Zhang W,Shen M,Wan P,Xiao F,Liu F,Zhang W,Tan Q,Liu X,Wu K,Liu Y,Li G,Wu J
Fri Nov 01 00:00:00 EDT 2019
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone.
Neurotoxicology
Sun C,Mo M,Wang Y,Yu W,Song C,Wang X,Chen S,Liu Y
Mon Jul 01 00:00:00 EDT 2019
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Neurological research
Yang Y,Shi Y,Jia J,Wang S,Chang H,Li M,Jin X,Wang J
Tue Oct 01 00:00:00 EDT 2019
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
Clinical and experimental pharmacology & physiology
Li M,Xu S,Geng Y,Sun L,Wang R,Yan Y,Wang H,Li Y,Yi Q,Zhang Y,Hao J,Deng C,Li W,Xue L
Fri Nov 01 00:00:00 EDT 2019
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Biological trace element research
Feng Z,Liang C,Manthari RK,Wang C,Zhang J
Fri Feb 01 00:00:00 EST 2019
The status of ω-3 PUFAs influence chronic unpredicted mild stress-induced metabolic side effects in rats through INSIG/SREBP pathway.
Food & function
Tang M,Floyd S,Cai H,Zhang M,Yang R,Dang R
Thu Aug 01 00:00:00 EDT 2019
Bergenin Ameliorates MPTP-Induced Parkinson's Disease by Activating PI3K/Akt Signaling Pathway.
Journal of Alzheimer's disease : JAD
Ji Y,Wang D,Zhang B,Lu H
Mon Nov 30 00:00:00 EST 2020
Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin.
Journal of experimental & clinical cancer research : CR
Shen Y,Li S,Wang X,Wang M,Tian Q,Yang J,Wang J,Wang B,Liu P,Yang J
Mon Oct 28 00:00:00 EDT 2019
Epigenetic Memory Is Involved in the Persistent Alterations of Drug-Processing Genes in Adult Mice Due to PCN-Activated PXR During Early Life.
Toxicological sciences : an official journal of the Society of Toxicology
Wang P,Liu G,Nie Y,Han S,Li J,Zhong XB,Zhang L
Fri Nov 01 00:00:00 EDT 2019
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Cell cycle (Georgetown, Tex.)
Wang Y,Han T,Gan M,Guo M,Xie C,Jin J,Zhang S,Wang P,Cao J,Wang JB
Wed May 01 00:00:00 EDT 2019
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
Cancer management and research
Pan C,Liu Q,Wu X
Mon Apr 11 00:00:00 EDT 2022
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Cell proliferation
Qin Y,Hu Q,Ji S,Xu J,Dai W,Liu W,Xu W,Sun Q,Zhang Z,Ni Q,Yu X,Zhang B,Xu X
Wed May 01 00:00:00 EDT 2019
CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging.
Stem cells international
Rui YF,Chen MH,Li YJ,Xiao LF,Geng P,Wang P,Xu ZY,Zhang XP,Dai GC
Thu Oct 01 00:00:00 EDT 2020
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Oxidative medicine and cellular longevity
Zheng GH,Shan Q,Mu JJ,Wang YJ,Zhang ZF,Fan SH,Hu B,Li MQ,Xie J,Chen P,Wu DM,Lu J,Zheng YL
Mon Mar 25 00:00:00 EDT 2019
Transcriptome sequencing of Eospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen.
Molecular biology reports
Xu L,Hao Z,Lin J,Zhao Q,Zhang B,Li G,He J,Li J
Sun Dec 01 00:00:00 EST 2019
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Biochimica et biophysica acta. Gene regulatory mechanisms
Shao J,Han B,Cao P,Zhang B,Liu M,Li D,Zhou N,Hao Q,Duan X,Chang Y,Nakai A,Fan Y,Tan K
Thu Aug 01 00:00:00 EDT 2019
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Frontiers in endocrinology
Zhou J,Yang J,Wang X,Li M,Li F,Zhu E,Li X,Li X,Wang B
Sun Jan 26 00:00:00 EST 2020
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Experimental cell research
Liu JZ,Hu YL,Feng Y,Guo YB,Liu YF,Yang JL,Mao QS,Xue WJ
Sun Dec 15 00:00:00 EST 2019
The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors.
Chemosphere
Mi P,Zhang QP,Zhang SH,Wang C,Zhang SZ,Fang YC,Gao JZ,Feng DF,Chen DY,Feng XZ
Thu Aug 01 00:00:00 EDT 2019
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response.
Journal of neuroinflammation
Yang RC,Qu XY,Xiao SY,Li L,Xu BJ,Fu JY,Lv YJ,Amjad N,Tan C,Kim KS,Chen HC,Wang XR
Wed May 15 00:00:00 EDT 2019
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance.
Science advances
Pan RY,Ma J,Kong XX,Wang XF,Li SS,Qi XL,Yan YH,Cheng J,Liu Q,Jin W,Tan CH,Yuan Z
Fri Feb 01 00:00:00 EST 2019
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
American journal of translational research
Bhandari A,Guan Y,Xia E,Huang Q,Chen Y
Thu Oct 01 00:00:00 EDT 2020
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells.
Virologica Sinica
Yu H,Ou-Yang YY,Li N,Nakai M,Huang GH
Thu Aug 01 00:00:00 EDT 2019
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Journal of experimental & clinical cancer research : CR
Wang A,Dai H,Gong Y,Zhang C,Shu J,Luo Y,Jiang Y,Liu W,Bie P
Thu Aug 08 00:00:00 EDT 2019
HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription.
Antiviral research
Yuan Y,Zhao K,Yao Y,Liu C,Chen Y,Li J,Wang Y,Pei R,Chen J,Hu X,Zhou Y,Wu C,Chen X
Sun Dec 01 00:00:00 EST 2019
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT1R/ROS/p38 MAPK/ADAM17 pathway.
American journal of physiology. Cell physiology
Zhang Y,Wang Y,Zhou D,Zhang LS,Deng FX,Shu S,Wang LJ,Wu Y,Guo N,Zhou J,Yuan ZY
Tue Oct 01 00:00:00 EDT 2019
Overexpression of CBX2 in breast cancer promotes tumor progression through the PI3K/AKT signaling pathway.
American journal of translational research
Zheng S,Lv P,Su J,Miao K,Xu H,Li M
Sat Apr 09 00:00:00 EDT 2022
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Du W,Wang N,Li F,Jia K,An J,Liu Y,Wang Y,Zhu L,Zhao S,Hao J
Mon Jul 01 00:00:00 EDT 2019
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
Microscopy research and technique
He X,Jiang H,Gao F,Liang S,Wei M,Chen L
Sun Dec 01 00:00:00 EST 2019
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Environment international
Shen X,Chen Y,Zhang J,Yan X,Liu W,Guo Y,Shan Q,Liu S
Mon Jul 01 00:00:00 EDT 2019
Shuangyu Tiaozhi Granule Attenuates Hypercholesterolemia through the Reduction of Cholesterol Synthesis in Rat Fed a High Cholesterol Diet.
BioMed research international
Shi J,Li R,Liu Y,Lu H,Yu L,Zhang F
Mon Jul 22 00:00:00 EDT 2019
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
European journal of pharmacology
Mo D,Tian W,Zhang HN,Feng YD,Sun Y,Quan W,Hao XW,Wang XY,Liu XX,Li C,Cao W,Liu WJ,Li XQ
Fri Nov 15 00:00:00 EST 2019
Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia.
Aging
Yang E,Cai Y,Yao X,Liu J,Wang Q,Jin W,Wu Q,Fan W,Qiu L,Kang C,Wu J
Mon Nov 18 00:00:00 EST 2019
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Toxicology mechanisms and methods
Lanxiang W,Bin W,Ge X,Yutang H,Chunjie W,Honghao Z
Fri Nov 01 00:00:00 EDT 2019
8-bromo-7-methoxychrysin targets NF-κB and FoxM1 to inhibit lung cancer stem cells induced by pro-inflammatory factors.
Journal of Cancer
Yuan Q,Wen M,Xu C,Chen A,Qiu YB,Cao JG,Zhang JS,Song ZW
Fri Jan 06 00:00:00 EST 2023
Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells.
Molecular immunology
Zhang J,Zheng Y,Luo Y,Du Y,Zhang X,Fu J
Sun Dec 01 00:00:00 EST 2019
Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis.
International journal of oncology
Sang Y,Sun L,Wu Y,Yuan W,Liu Y,Li SW
Fri Mar 01 00:00:00 EST 2019
Hypoxia enhances IL-10-producing B cell generation through upregulating high-mobility group B1 on tumor cell-released autophagosomes.
Immunology letters
Zhang Y,Pan N,Sheng Y,Zhou M,Wen Z,Chen Y,Huang F,Wang LX
Sun Dec 01 00:00:00 EST 2019
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Cancer management and research
Xiao H,Cheng Q,Wu X,Tang Y,Liu J,Li X
Sun Apr 10 00:00:00 EDT 2022
The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
Frontiers in cellular neuroscience
Song L,Tang S,Dong L,Han X,Cong L,Dong J,Han X,Zhang Q,Wang Y,Du Y
Thu Oct 01 00:00:00 EDT 2020
Melatonin Receptor Mel1b- and Mel1c-mediated Green Light Induced the Secretion of Growth Hormone in Anterior Pituitary of Chicks.
Photochemistry and photobiology
Yue L,Qin X,Liu X,Wang Z,Dong Y,Chen Y,Cao J
Fri Nov 01 00:00:00 EDT 2019
Fe3O4@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Colloids and surfaces. B, Biointerfaces
Sun Y,Shi F,Niu Y,Zhang Y,Xiong F
Sun Dec 01 00:00:00 EST 2019
Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu Y,Li Y,Wang Z,Xie S,Wang Q,Lei X,Ruan Y,Li J
Mon Apr 01 00:00:00 EDT 2019
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
Journal of experimental & clinical cancer research : CR
Ma B,Zhang L,Zou Y,He R,Wu Q,Han C,Zhang B
Fri Jan 18 00:00:00 EST 2019
Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.
Journal of experimental & clinical cancer research : CR
Ma B,Zhang L,Zou Y,He R,Wu Q,Han C,Zhang B
Fri Jan 18 00:00:00 EST 2019
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.
Theranostics
Song Y,Zhang C,Zhang J,Jiao Z,Dong N,Wang G,Wang Z,Wang L
Thu Jun 25 00:00:00 EDT 2020
[6]-Gingerol enhances the cisplatin sensitivity of gastric cancer cells through inhibition of proliferation and invasion via PI3K/AKT signaling pathway.
Phytotherapy research : PTR
Luo Y,Zha L,Luo L,Chen X,Zhang Q,Gao C,Zhuang X,Yuan S,Qiao T
Wed May 01 00:00:00 EDT 2019
Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota.
The American journal of Chinese medicine
Wang J,Shao L,Rao T,Zhang W,Huang WH
Fri Feb 07 00:00:00 EST 2020
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
FEBS open bio
Wu H,He Y,Chen H,Liu Y,Wei B,Chen G,Lin H,Lin H
Mon Apr 01 00:00:00 EDT 2019
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
Archives of virology
Ouyang Y,Xu L,Lv J,Hou Y,Fan Z,Xu P,Jiang Y,Wu M,Li R,Zhang Y,Guo K
Wed May 01 00:00:00 EDT 2019
The Autographa californica Multiple Nucleopolyhedrovirus ac51 Gene Is Required for Efficient Nuclear Egress of Nucleocapsids and Is Essential for In Vivo Virulence.
Journal of virology
Qiu J,Tang Z,Cai Y,Wu W,Yuan M,Yang K
Fri Feb 01 00:00:00 EST 2019
Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux.
Frontiers in behavioral neuroscience
Chen SM,Yi YL,Zeng D,Tang YY,Kang X,Zhang P,Zou W,Tang XQ
Mon Apr 11 00:00:00 EDT 2022
ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.
Lipids
Wang N,Lu HY,Li X,Du YJ,Meng WH,Ding HW,Zhao QC
Wed May 01 00:00:00 EDT 2019
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Thoracic cancer
Gan H,Lin L,Hu N,Yang Y,Gao Y,Pei Y,Chen K,Sun B
Mon Apr 01 00:00:00 EDT 2019
LncRNA SNHG4 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition of lung cancer cells by regulating miR-98-5p.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Tang Y,Wu L,Zhao M,Zhao G,Mao S,Wang L,Liu S,Wang X
Sun Dec 01 00:00:00 EST 2019
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Biochemical pharmacology
Zhu Y,Zuo W,Chen L,Bian S,Jing J,Gan C,Wu X,Liu H,Su X,Hu W,Guo Y,Wang Y,Ye T
Fri Nov 01 00:00:00 EDT 2019
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone induced apoptosis and G1 cell cycle arrest through PI3K/AKT pathway in BEL-7402/5-FU cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ji X,Wei X,Qian J,Mo X,Kai G,An F,Lu Y
Sun Sep 01 00:00:00 EDT 2019
Glial response in early stages of traumatic brain injury.
Neuroscience letters
Zhao J,Wang B,Huang T,Guo X,Yang Z,Song J,Zhang M
Sat Aug 24 00:00:00 EDT 2019
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Journal of agricultural and food chemistry
Yang Z,Liu G,Wang Y,Yin J,Wang J,Xia B,Li T,Yang X,Hou P,Hu S,Song W,Guo S
Wed May 22 00:00:00 EDT 2019
Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway.
Oncology letters
Zhang L,Cai QY,Liu J,Peng J,Chen YQ,Sferra TJ,Lin JM
Sun Sep 01 00:00:00 EDT 2019
SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes.
Cell death & disease
Jia D,Wang YY,Wang P,Huang Y,Liang DY,Wang D,Cheng C,Zhang C,Guo L,Liang P,Wang Y,Jia Y,Li C
Fri Jan 25 00:00:00 EST 2019
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Toxicology and applied pharmacology
Yu Z,Jv Y,Cai L,Tian X,Huo X,Wang C,Zhang B,Sun C,Ning J,Feng L,Zhang H,Ma X
Wed May 15 00:00:00 EDT 2019
PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis.
Journal of orthopaedic surgery and research
Liu S,Cao C,Zhang Y,Liu G,Ren W,Ye Y,Sun T
Wed Dec 11 00:00:00 EST 2019
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway.
Cancer management and research
Guo X,Yan Z,Zhang G,Wang X,Pan Y,Huang M
Tue Apr 12 00:00:00 EDT 2022
Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats.
Oxidative medicine and cellular longevity
Zhang HF,Wang JH,Wang YL,Gao C,Gu YT,Huang J,Wang JH,Zhang Z
Thu Aug 08 00:00:00 EDT 2019
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Frontiers in pharmacology
Li B,He X,Lei SS,Zhou FC,Zhang NY,Chen YH,Wang YZ,Su J,Yu JJ,Li LZ,Zheng X,Luo R,Kołodyńska D,Xiong S,Lv GY,Chen SH
Mon Sep 28 00:00:00 EDT 2020
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus.
Nature communications
Xue M,Zhao BS,Zhang Z,Lu M,Harder O,Chen P,Lu Z,Li A,Ma Y,Xu Y,Liang X,Zhou J,Niewiesk S,Peeples ME,He C,Li J
Wed Oct 09 00:00:00 EDT 2019
High-level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer.
Journal of surgical oncology
Wang F,Hu YL,Feng Y,Guo YB,Liu YF,Mao QS,Xue WJ
Sat Jun 01 00:00:00 EDT 2019
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response.
Frontiers in genetics
Tang GH,Chen X,Ding JC,Du J,Lin XT,Xia L,Lian JB,Ye F,He XS,Liu W
Mon Sep 28 00:00:00 EDT 2020
MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.
Frontiers in pediatrics
Wang X,Ding YY,Chen Y,Xu QQ,Qian GH,Qian WG,Cao L,Zhou WP,Hou M,Lv HT
Thu Oct 01 00:00:00 EDT 2020
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
Cell research
Zhong F,Hu Z,Jiang K,Lei B,Wu Z,Yuan G,Luo H,Dong C,Tang B,Zheng C,Yang S,Zeng Y,Guo Z,Yu S,Su H,Zhang G,Qiu X,Tomlinson S,He S
Mon Jul 01 00:00:00 EDT 2019
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Journal of neuroinflammation
Zhang B,Wang G,He J,Yang Q,Li D,Li J,Zhang F
Mon Apr 22 00:00:00 EDT 2019
Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.
Oxidative medicine and cellular longevity
Huang T,Zhou F,Yuan X,Yang T,Liang X,Wang Y,Tu H,Chang J,Nan K,Wei Y
Fri Jan 03 00:00:00 EST 2020
Recombinant porcine NK-lysin inhibits the invasion of hepatocellular carcinoma cells in vitro.
International journal of biological macromolecules
Khan A,Fan K,Sun N,Yin W,Sun Y,Sun P,Jahejo AR,Li H
Fri Nov 01 00:00:00 EDT 2019
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
PloS one
Chen KY,Chen CC,Chang YC,Chang MC
Mon Mar 16 00:00:00 EDT 2020
CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Luo Y,Liu Y,Wu L,Ma X,Liu Q,Huang F,Zhang X,Zhang Y,Zhang J,Luo H,Yang Y,Lu G,Tang X,Li L,Zeng Y,Pan T,Zhang H
Mon Jul 01 00:00:00 EDT 2019
Temporal induction of intestinal epithelial hypoxia-inducible factor-2α is sufficient to drive colitis.
American journal of physiology. Gastrointestinal and liver physiology
Solanki S,Devenport SN,Ramakrishnan SK,Shah YM
Thu Aug 01 00:00:00 EDT 2019
Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.
BMC complementary and alternative medicine
Que Z,Zhou Z,Luo B,Dong C,Jiang Y,Li H,Tian J
Wed Aug 07 00:00:00 EDT 2019
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Bioscience reports
Xiong Y,Lu J,Fang Q,Lu Y,Xie C,Wu H,Yin Z
Tue Apr 30 00:00:00 EDT 2019
Da-Bu-Yin-Wan and Qian-Zheng-San Ameliorate Mitochondrial Dynamics in the Parkinson's Disease Cell Model Induced by MPP.
Frontiers in pharmacology
Gai C,Feng WD,Qiang TY,Ma HJ,Chai Y,Zhang SJ,Guo ZY,Hu JH,Sun HM
Wed Sep 30 00:00:00 EDT 2020
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Nature microbiology
Guo T,Zuo Y,Qian L,Liu J,Yuan Y,Xu K,Miao Y,Feng Q,Chen X,Jin L,Zhang L,Dong C,Xiong S,Zheng H
Fri Nov 01 00:00:00 EDT 2019
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Frontiers in physiology
Zhong W,Shi X,Yuan H,Bu H,Wu L,Wang R
Wed Sep 30 00:00:00 EDT 2020
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
Molecules (Basel, Switzerland)
Ai Z,Liu S,Qu F,Zhang H,Chen Y,Ni D
Tue Mar 26 00:00:00 EDT 2019
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Viruses
Yang S,Liu B,Yin S,Shang Y,Zhang X,Khan MUZ,Liu X,Cai J
Sun Nov 03 00:00:00 EDT 2019
The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling.
Frontiers in pharmacology
Gong X,Hu H,Qiao Y,Xu P,Yang M,Dang R,Han W,Guo Y,Chen D,Jiang P
Tue Sep 29 00:00:00 EDT 2020
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells.
Biomolecules
Guo X,Wu S,Li N,Lin Q,Liu L,Liang H,Niu Y,Huang Z,Fu X
Mon Sep 02 00:00:00 EDT 2019
Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway.
BMC complementary and alternative medicine
Tian S,Wang M,Liu C,Zhao H,Zhao B
Thu Nov 21 00:00:00 EST 2019
Grouper Atg12 negatively regulates the antiviral immune response against Singapore grouper iridovirus (SGIV) infection.
Fish & shellfish immunology
Li C,Yu Y,Zhang X,Wei J,Qin Q
Tue Oct 01 00:00:00 EDT 2019
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
International immunopharmacology
Le K,Chibaatar Daliv E,Wu S,Qian F,Ali AI,Yu D,Guo Y
Tue Oct 01 00:00:00 EDT 2019
Observation of novel COX20 mutations related to autosomal recessive axonal neuropathy and static encephalopathy.
Human genetics
Xu H,Ji T,Lian Y,Wang S,Chen X,Li S,Yin Y,Dong X
Mon Jul 01 00:00:00 EDT 2019
SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.
PloS one
Wang M,Wang Y,Liu Y,Wang H,Xin X,Li J,Hao Y,Han L,Yu F,Zheng C,Shen C
Mon Mar 02 00:00:00 EST 2020
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Journal of Cancer
Bi Y,Kong P,Zhang L,Cui H,Xu X,Chang F,Yan T,Li J,Cheng C,Song B,Niu X,Liu X,Liu X,Xu E,Hu X,Qian Y,Wang F,Li H,Ma Y,Yang J,Liu Y,Zhai Y,Wang Y,Zhang Y,Liu H,Liu J,Wang J,Cui Y,Cheng X
Thu Oct 01 00:00:00 EDT 2020
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming.
Cells
Cheng X,Tan Z,Huang X,Yuan Y,Qin S,Gu Y,Wang D,He C,Su Z
Tue Jun 11 00:00:00 EDT 2019
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.
ACS chemical biology
Ward CC,Kleinman JI,Brittain SM,Lee PS,Chung CYS,Kim K,Petri Y,Thomas JR,Tallarico JA,McKenna JM,Schirle M,Nomura DK
Fri Nov 15 00:00:00 EST 2019
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
PLoS pathogens
Lin L,Xu L,Lv W,Han L,Xiang Y,Fu L,Jin M,Zhou R,Chen H,Zhang A
Sat Jun 01 00:00:00 EDT 2019
Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways.
Oxidative medicine and cellular longevity
He M,Shi W,Yu M,Li X,Xu J,Zhu J,Jin L,Xie W,Kong H
Tue Jul 09 00:00:00 EDT 2019
Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Liang Y,Zhang Q,Zhang L,Wang R,Xu X,Hu X
Wed Sep 30 00:00:00 EDT 2020
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer.
Bioscience reports
Wang D,Dai J,Hou S,Qian Y
Tue Apr 30 00:00:00 EDT 2019
SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells.
Mucosal immunology
Dai L,Liu Y,Cheng L,Wang H,Lin Y,Shi G,Dong Z,Li J,Fan P,Wang Q,Su X,Zhang S,Yang Y,Hu X,Huang W,Zhou Z,Yu D,Probert C,Wei Y,Deng H
Sun Sep 01 00:00:00 EDT 2019
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Molecules (Basel, Switzerland)
Hu Y,Li Q,Pan Y,Xu L
Tue Dec 03 00:00:00 EST 2019
BMAL1 Disrupted Intrinsic Diurnal Oscillation in Rat Cerebrovascular Contractility of Simulated Microgravity Rats by Altering Circadian Regulation of miR-103/CaV1.2 Signal Pathway.
International journal of molecular sciences
Chen L,Zhang B,Yang L,Bai YG,Song JB,Ge YL,Ma HZ,Cheng JH,Ma J,Xie MJ
Wed Aug 14 00:00:00 EDT 2019
HSF2 regulates aerobic glycolysis by suppression of FBP1 in hepatocellular carcinoma.
American journal of cancer research
Yang LN,Ning ZY,Wang L,Yan X,Meng ZQ
Thu Oct 01 00:00:00 EDT 2020
Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells.
Chemical research in toxicology
Hao Z,Zhang Z,Lu D,Ding B,Shu L,Zhang Q,Wang C
Mon Jun 17 00:00:00 EDT 2019
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells.
Biochemical and biophysical research communications
Zhang D,Zhou Q,Huang D,He L,Zhang H,Hu B,Peng H,Ren D
Tue Jun 04 00:00:00 EDT 2019
A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways.
Cancer letters
Dong Q,Yang B,Han JG,Zhang MM,Liu W,Zhang X,Yu HL,Liu ZG,Zhang SH,Li T,Wu DD,Ji XY,Duan SF
Sun Jul 28 00:00:00 EDT 2019
Self-Assembled saRNA Delivery System Based on Rolling Circle Transcription for Aptamer-Targeting Cancer Therapy.
ACS applied bio materials
Wang T,Hong S,Luo Y,Lv H,Zhang Y,Pei R
Mon Nov 18 00:00:00 EST 2019
MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression.
OncoTargets and therapy
Liang W,Li C,Li M,Wang D,Zhong Z
Sun Apr 10 00:00:00 EDT 2022
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
International journal of nanomedicine
Khan MW,Zhao P,Khan A,Raza F,Raza SM,Sarfraz M,Chen Y,Li M,Yang T,Ma X,Xiang G
Fri Aug 30 00:00:00 EDT 2019
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Bioscience reports
Li H,Wu W,He X,Cao C,Yu X,Zeng Y,Li L
Mon Sep 30 00:00:00 EDT 2019
Comparison of the Effects of Green and Black Tea Extracts on Na+ /K+ -ATPase Activity in Intestine of Type 1 and Type 2 Diabetic Mice.
Molecular nutrition & food research
Qu F,Liu S,He C,Zhou J,Zhang S,Ai Z,Chen Y,Yu Z,Ni D
Sun Sep 01 00:00:00 EDT 2019
Gatifloxacin inducing apoptosis of stromal fibroblasts through cross-talk between caspase-dependent extrinsic and intrinsic pathways.
International journal of ophthalmology
Xu B,Sui YL,Fan TJ
Wed Sep 30 00:00:00 EDT 2020
Fine particulate matters induce apoptosis via the ATM/P53/CDK2 and mitochondria apoptosis pathway triggered by oxidative stress in rat and GC-2spd cell.
Ecotoxicology and environmental safety
Liu J,Zhang J,Ren L,Wei J,Zhu Y,Duan J,Jing L,Sun Z,Zhou X
Mon Sep 30 00:00:00 EDT 2019
Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression.
Nature communications
Zhang J,Bai R,Li M,Ye H,Wu C,Wang C,Li S,Tan L,Mai D,Li G,Pan L,Zheng Y,Su J,Ye Y,Fu Z,Zheng S,Zuo Z,Liu Z,Zhao Q,Che X,Xie D,Jia W,Zeng MS,Tan W,Chen R,Xu RH,Zheng J,Lin D
Tue Apr 23 00:00:00 EDT 2019
Hepatocyte nuclear factor 1 alpha (HNF1A) regulates transcription of O-GlcNAc transferase in a negative feedback mechanism.
FEBS letters
Zhang C,Xie F,Li L,Zhang C,Zhang Y,Ying W,Liu L,Yan X,Yin F,Zhang L
Wed May 01 00:00:00 EDT 2019
Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin.
Journal of Cancer
Peng Y,Wang L,Wu L,Zhang L,Nie G,Guo M
Thu Oct 01 00:00:00 EDT 2020
Kibra Modulates Learning and Memory via Binding to Dendrin.
Cell reports
Ji Z,Li H,Yang Z,Huang X,Ke X,Ma S,Lin Z,Lu Y,Zhang M
Tue Feb 19 00:00:00 EST 2019
Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.
Cancers
Konen JM,Rodriguez BL,Fradette JJ,Gibson L,Davis D,Minelli R,Peoples MD,Kovacs J,Carugo A,Bristow C,Heffernan T,Gibbons DL
Tue Apr 02 00:00:00 EDT 2019
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma.
European review for medical and pharmacological sciences
Luo XF,Wu XJ,Wei X,Wang AG,Wang SH,Wang JL
Tue Oct 01 00:00:00 EDT 2019
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.
Journal of cellular and molecular medicine
Gao X,Wang J,Li M,Wang J,Lv J,Zhang L,Sun C,Ji J,Yang W,Zhao Z,Mao W
Tue Oct 01 00:00:00 EDT 2019
BPTF cooperates with p50 NF-κB to promote COX-2 expression and tumor cell growth in lung cancer.
American journal of translational research
Dai M,Hu S,Liu CF,Jiang L,Yu W,Li ZL,Guo W,Tang R,Dong CY,Wu TH,Deng WG
Thu Oct 01 00:00:00 EDT 2020
Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nature communications
Zhang R,Xu G,Cao L,Sun Z,He Y,Cui M,Sun Y,Li S,Li H,Qin L,Hu M,Yuan Z,Rao Z,Ding W,Rao Z,Lou Z
Wed Aug 21 00:00:00 EDT 2019
NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
Cancer chemotherapy and pharmacology
Liu L,Chen J,Cao M,Wang J,Wang S
Sun Dec 01 00:00:00 EST 2019
Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.
Evidence-based complementary and alternative medicine : eCAM
Xia CH,Han XT,Zhang X,Zhu ZB,Guo J,Cui HL,Jiang HX,Huang WJ,Chen GZ,Liu YN,Liu WJ
Wed Sep 30 00:00:00 EDT 2020
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.
International immunopharmacology
Duan J,Gao Y,Zhang X,Wang X,Wang B,Meng X,Yoshikai Y,Wang Y,Sun X
Sat Jun 01 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
A maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independently of maternal mitochondrial inheritance.
American journal of physiology. Heart and circulatory physiology
Ferey JLA,Boudoures AL,Reid M,Drury A,Scheaffer S,Modi Z,Kovacs A,Pietka T,DeBosch BJ,Thompson MD,Diwan A,Moley KH
Wed May 01 00:00:00 EDT 2019
PLZF regulates apoptosis of leukemia cells by regulating AKT/Foxo3a pathway.
European review for medical and pharmacological sciences
Li JX,Zhang ZF,Wang XB,Yang EQ,Dong L,Meng J
Thu Aug 01 00:00:00 EDT 2019
Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway.
Aging
Wang Y,Zuo R,Wang Z,Luo L,Wu J,Zhang C,Liu M,Shi C,Zhou Y
Mon Sep 23 00:00:00 EDT 2019
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Evidence-based complementary and alternative medicine : eCAM
Li L,Jiang H,Wei X,Geng D,He M,Du H
Mon Sep 28 00:00:00 EDT 2020
Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.
Apoptosis : an international journal on programmed cell death
Wu M,Chen W,Zhang S,Huang S,Zhang A,Zhang Y,Jia Z
Sun Dec 01 00:00:00 EST 2019
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway.
BioMed research international
Huang F,Chen J,Wang J,Zhu P,Lin W
Mon Apr 20 00:00:00 EDT 2020
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
PLoS genetics
Wang P,Deng J,Dong J,Liu J,Bigio EH,Mesulam M,Wang T,Sun L,Wang L,Lee AY,McGee WA,Chen X,Fushimi K,Zhu L,Wu JY
Wed May 01 00:00:00 EDT 2019
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Experimental lung research
Wu ZL,Wang J
Tue Oct 01 00:00:00 EDT 2019
CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition.
Journal of oncology
Simbulan-Rosenthal CM,Gaur A,Zhou H,AbdusSamad M,Qin Q,Dougherty R,Aljehane L,Kuo LW,Vakili S,Karna K,Clark H,McCarron E,Rosenthal DS
Thu Oct 01 00:00:00 EDT 2020
Curcumin exerts cytotoxicity dependent on reactive oxygen species accumulation in non-small-cell lung cancer cells.
Future oncology (London, England)
Wang C,Song X,Shang M,Zou W,Zhang M,Wei H,Shao H
Mon Apr 01 00:00:00 EDT 2019
Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway.
Chemical research in toxicology
Li X,Huo C,Xiao Y,Xu R,Liu Y,Jia X,Wang X
Mon Sep 16 00:00:00 EDT 2019
Curcumin and Resveratrol Regulate Intestinal Bacteria and Alleviate Intestinal Inflammation in Weaned Piglets.
Molecules (Basel, Switzerland)
Gan Z,Wei W,Li Y,Wu J,Zhao Y,Zhang L,Wang T,Zhong X
Thu Mar 28 00:00:00 EDT 2019
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
Molecular and cellular biochemistry
Liu R,Xu X,Liang C,Chen X,Yu X,Zhong H,Xu W,Cheng Y,Wang W,Wu Y,Yu L,Hu X
Sat Jun 01 00:00:00 EDT 2019
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Cell death & disease
Hung MH,Chen YL,Chen LJ,Chu PY,Hsieh FS,Tsai MH,Shih CT,Chao TI,Huang CY,Chen KF
Wed May 29 00:00:00 EDT 2019
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Nature communications
Sang Y,Li Y,Zhang Y,Alvarez AA,Yu B,Zhang W,Hu B,Cheng SY,Feng H
Thu Sep 05 00:00:00 EDT 2019
RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
Wellcome open research
Frost J,Ciulli A,Rocha S
Wed Nov 15 00:00:00 EST 2023
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Cell death & disease
Xie K,Xu C,Zhang M,Wang M,Min L,Qian C,Wang Q,Ni Z,Mou S,Dai H,Pang H,Gu L
Wed Dec 04 00:00:00 EST 2019
Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway.
American journal of translational research
Jiang C,Liu H,Sun H,Wang X,Liao H,Ma L,Cao Z
Tue Sep 29 00:00:00 EDT 2020
Role of nuclear factor-κB pathway in the transition of mouse secondary follicles to antral follicles.
Journal of cellular physiology
Xu JJ,Wang G,Luo X,Wang LJ,Bao Y,Yang X
Sun Dec 01 00:00:00 EST 2019
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
Cell death & disease
Xu Q,Wu N,Li X,Guo C,Li C,Jiang B,Wang H,Shi D
Tue Nov 19 00:00:00 EST 2019
A novel RING finger protein CqRNF152-like with self-ubiquitination activity inhibits white spot syndrome virus infection in a crustacean Cherax quadricarinatus.
Fish & shellfish immunology
Zheng SC,Chang XJ,Li WD,Wang H,Guo LM,Wang KJ,Liu HP
Fri Nov 01 00:00:00 EDT 2019
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Cell communication and signaling : CCS
Hong W,Zhang G,Lu H,Guo Y,Zheng S,Zhu H,Xiao Y,Papa APD,Wu C,Sun L,Chen B,Bai Y
Tue Nov 12 00:00:00 EST 2019
Molecular cloning, expression and functional analysis of Atg16L1 from orange-spotted grouper (Epinephelus coioides).
Fish & shellfish immunology
Li C,Wang L,Zhang X,Wei J,Qin Q
Fri Nov 01 00:00:00 EDT 2019
Dexmedetomidine Attenuates Orthotopic Liver Transplantation-Induced Acute Gut Injury via α 2-Adrenergic Receptor-Dependent Suppression of Oxidative Stress.
Oxidative medicine and cellular longevity
Lv P,Chen T,Liu P,Zheng L,Tian J,Tan F,Chen J,Deng Y,Li J,Cai J,Chi X
Mon May 04 00:00:00 EDT 2020
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway.
Biological research
Wang G,Li Z,Li X,Zhang C,Peng L
Tue Dec 17 00:00:00 EST 2019
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Veterinary microbiology
Fang R,Du H,Lei G,Liu Y,Feng S,Ye C,Li N,Peng Y
Mon Apr 01 00:00:00 EDT 2019
Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
Cell death & disease
Liu J,An P,Xue Y,Che D,Liu X,Zheng J,Liu Y,Yang C,Li Z,Yu B
Wed Jun 05 00:00:00 EDT 2019
aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.
Journal of Alzheimer's disease : JAD
Cao Q,Meng T,Man J,Peng D,Chen H,Xiang Q,Su Z,Zhang Q,Huang Y
Thu Nov 05 00:00:00 EST 2020
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Oxidative medicine and cellular longevity
Qaed E,Wang J,Almoiliqy M,Song Y,Liu W,Chu P,Alademi S,Alademi M,Li H,Alshwmi M,Al-Azab M,Ahsan A,Mahdi S,Han G,Niu M,Ali A,Shopit A,Wang H,Li X,Qaid A,Ma X,Li T,Peng J,Ma J,Zhang J,Tang Z
Thu Jun 25 00:00:00 EDT 2020
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
OncoTargets and therapy
Chu C,Niu X,Ou X,Hu C
Sat Apr 09 00:00:00 EDT 2022
Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD.
Molecular omics
Cheng Z,Wen Y,Liang B,Chen S,Liu Y,Wang Z,Cheng J,Tang X,Xin H,Deng L
Mon Feb 11 00:00:00 EST 2019
S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.
Veterinary microbiology
Song Z,Bai J,Liu X,Nauwynck H,Wu J,Liu X,Jiang P
Sun Dec 01 00:00:00 EST 2019
Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor.
Frontiers in pharmacology
Zhang L,Li X,Chen Y,Wan M,Jiang Q,Zhang L,Chou CJ,Song W,Zhang L
Fri Oct 13 00:00:00 EDT 2023
SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.
Cell death & disease
Tan P,Xu Y,Du Y,Wu L,Guo B,Huang S,Zhu J,Li B,Lin F,Yao L
Thu Oct 17 00:00:00 EDT 2019
Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes.
International immunopharmacology
Hu F,Zhu D,Pei W,Lee I,Zhang X,Pan L,Xu J
Tue Oct 01 00:00:00 EDT 2019
MicroRNA-182-3p negatively regulates cytokines expression by targeting TLR5M in orange-spotted grouper, Epinephelus coioides.
Fish & shellfish immunology
He L,Zhao M,Yu X,Zhao Y,Fu L,Qiao X,Lin H,Zhang Y,Li G,Li S,Lu D
Tue Oct 01 00:00:00 EDT 2019
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Psychopharmacology
Zhang SS,Tian YH,Jin SJ,Wang WC,Zhao JX,Si XM,Zhang L,Xu H,Jin JY
Fri Nov 01 00:00:00 EDT 2019
Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.
The FEBS journal
Li G,Zhou S,Li C,Cai B,Yu H,Ma B,Huang Y,Ding Y,Liu Y,Ding Q,He C,Zhou J,Wang Y,Zhou G,Li Y,Yan Y,Hua J,Petersen B,Jiang Y,Sonstegard T,Huang X,Chen Y,Wang X
Sun Dec 01 00:00:00 EST 2019
Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Theranostics
Hu L,Ding M,Tang D,Gao E,Li C,Wang K,Qi B,Qiu J,Zhao H,Chang P,Fu F,Li Y
Mon Sep 14 00:00:00 EDT 2020
Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro.
Molecular immunology
Zhou Z,Li H,Tian S,Yi W,Zhou Y,Yang H,Li X,Wu B,Li X,Wu J,Wang Z,Hu S,Fang R
Sun Dec 01 00:00:00 EST 2019
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Research in veterinary science
Li L,Wu J,Cao X,Zhou J,Yin S,Yang S,Feng Q,Du P,Liu Y,Shang Y,Liu Y,Liu X
Thu Aug 01 00:00:00 EDT 2019
The fucoidan A3 from the seaweed Ascophyllum nodosum enhances RCT-related genes expression in hyperlipidemic C57BL/6J mice.
International journal of biological macromolecules
Yang Z,Yin J,Wang Y,Wang J,Xia B,Li T,Yang X,Hu S,Ji C,Guo S
Thu Aug 01 00:00:00 EDT 2019
MiR-34s negatively regulate homologous recombination through targeting RAD51.
Archives of biochemistry and biophysics
Chen S,Liu R,Wang Q,Qi Z,Hu Y,Zhou P,Wang Z
Wed May 15 00:00:00 EDT 2019
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Experimental and therapeutic medicine
Lu J,Meng Z,Cheng B,Liu M,Tao S,Guan S
Tue Oct 01 00:00:00 EDT 2019
A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue-derived stem cells pretreated by defocused low-energy shock wave.
Journal of tissue engineering and regenerative medicine
Zhang H,Zhao Y,Wang M,Song W,Sun P,Jin X
Sat Jun 01 00:00:00 EDT 2019
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
Aging
Guan R,Cai Z,Wang J,Ding M,Li Z,Xu J,Li Y,Li J,Yao H,Liu W,Qian J,Deng B,Tang C,Sun D,Lu W
Mon Dec 23 00:00:00 EST 2019
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
International journal of medical sciences
Wang Q,Jia S,Jiao Y,Xu L,Wang D,Chen X,Hu X,Liang H,Wen N,Zhang S,Guo B,Zhang L
Thu Apr 30 00:00:00 EDT 2020
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Human gene therapy
Xu Y,Wang X,Guo B,Wang D,Kalvakolanu DV,Chen X,Tang J,Zhang L,Yang Q
Fri Nov 01 00:00:00 EDT 2019
Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation.
EBioMedicine
Wu Y,Qin YH,Liu Y,Zhu L,Zhao XX,Liu YY,Luo SW,Tang GS,Shen Q
Sun Sep 01 00:00:00 EDT 2019
Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
The Journal of biological chemistry
Zhang X,Tu H,Yang Y,Jiang X,Hu X,Luo Q,Li J
Fri Aug 09 00:00:00 EDT 2019
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Experimental & molecular medicine
Zhang X,Ge Y,Bukhari AA,Zhu Q,Shen Y,Li M,Sun H,Su D,Liang X
Tue May 21 00:00:00 EDT 2019
Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer.
The international journal of biochemistry & cell biology
Wang S,Zhang J,Wang T,Ren F,Liu X,Lu Y,Xu L,Zhang Y,Wang D,Xu L,Wu Y,Liu F,Li Q,Zaky MY,Liu S,Dong W,Liu F,Zou K,Zhang Y
Sun Dec 01 00:00:00 EST 2019
miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer.
OncoTargets and therapy
Wang K,Lü H,Qu H,Xie Q,Sun T,Gan O,Hu B
Tue Apr 12 00:00:00 EDT 2022
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury.
Neuroscience
Zhu Z,Hu Y,Zhou Y,Zhang Y,Yu L,Tao L,Guo A,Fang Q
Sat Jun 01 00:00:00 EDT 2019
CLEC4M is associated with poor prognosis and promotes cisplatin resistance in NSCLC patients.
Journal of Cancer
Tan LM,Li X,Qiu CF,Zhu T,Hu CP,Yin JY,Zhang W,Zhou HH,Liu ZQ
Thu Oct 01 00:00:00 EDT 2020
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Environment international
Chen S,Li D,Zhang H,Yu D,Chen R,Zhang B,Tan Y,Niu Y,Duan H,Mai B,Chen S,Yu J,Luan T,Chen L,Xing X,Li Q,Xiao Y,Dong G,Niu Y,Aschner M,Zhang R,Zheng Y,Chen W
Tue Oct 01 00:00:00 EDT 2019
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Cancer letters
Che Y,Li Y,Zheng F,Zou K,Li Z,Chen M,Hu S,Tian C,Yu W,Guo W,Luo M,Deng W,Zou L
Fri Jun 28 00:00:00 EDT 2019
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways.
Cell death & disease
Li X,Yang Z,Nie W,Jiang J,Li S,Li Z,Tian L,Ma X
Wed Sep 18 00:00:00 EDT 2019
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Frontiers in pharmacology
Liu F,Li Z,He X,Yu H,Feng J
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Leukemia & lymphoma
Jiang X,Cheng Y,Hu C,Zhang A,Ren Y,Xu X
Mon Jul 01 00:00:00 EDT 2019
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5.
Leukemia & lymphoma
Jiang X,Cheng Y,Hu C,Zhang A,Ren Y,Xu X
Mon Jul 01 00:00:00 EDT 2019
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Nature communications
Ramakrishnan SK,Zhang H,Ma X,Jung I,Schwartz AJ,Triner D,Devenport SN,Das NK,Xue X,Zeng MY,Hu Y,Mortensen RM,Greenson JK,Cascalho M,Wobus CE,Colacino JA,Nunez G,Rui L,Shah YM
Fri Feb 08 00:00:00 EST 2019
Integration of transcriptomics and network analysis deciphers the mechanisms of baicalein in improving learning and memory impairment in senescence-accelerated mouse prone 8 (SAMP8).
European journal of pharmacology
Li J,Zhou Y,Du G,Qin X,Gao L
Sun Dec 15 00:00:00 EST 2019
SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells.
International journal of ophthalmology
Han X,Dong XX,Shi MY,Feng L,Wang XL,Zhang JS,Yan QC
Wed Sep 30 00:00:00 EDT 2020
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
Cell death & disease
Mao S,Huang T,Chen Y,Shen L,Zhou S,Zhang S,Yu B
Thu Oct 17 00:00:00 EDT 2019
Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
Pigment cell & melanoma research
Mikheil DM,Prabhakar K,Arshad A,Rodriguez CI,Newton MA,Setaluri V
Mon Jul 01 00:00:00 EDT 2019
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
Journal of cellular biochemistry
Wang S,Zhang S,He Y,Huang X,Hui Y,Tang Y
Sun Sep 01 00:00:00 EDT 2019
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Neurochemical research
Liu H,Yang J,Wang K,Niu T,Huang D
Wed May 01 00:00:00 EDT 2019
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Biochemical and biophysical research communications
Wang H,Liu Y,Shi J,Cheng Z
Tue Aug 27 00:00:00 EDT 2019
miR-33 and RIP140 participate in LPS-induced acute lung injury.
Turkish journal of medical sciences
Li H,Hou H,Liu S,Feng Y,Zhong W,Hu X,Yan N
Mon Feb 11 00:00:00 EST 2019
Anti-osteoporosis effects of osteoking via reducing reactive oxygen species.
Journal of ethnopharmacology
Qin D,Zhang H,Zhang H,Sun T,Zhao H,Lee WH
Fri Nov 15 00:00:00 EST 2019
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
Journal of autoimmunity
Liu B,Gu Y,Pei S,Peng Y,Chen J,Pham LV,Shen HY,Zhang J,Wang H
Thu Aug 01 00:00:00 EDT 2019
Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury.
Biomarkers in medicine
Xiao J,Lin H,Liu B,Xia Z,Zhang J,Jin J
Sat Jun 01 00:00:00 EDT 2019
The nanoparticle-facilitated autophagy inhibition of cancer stem cells for improved chemotherapeutic effects on glioblastomas.
Journal of materials chemistry. B
Lu L,Shen X,Tao B,Lin C,Li K,Luo Z,Cai K
Thu Mar 28 00:00:00 EDT 2019
MiR-16a Regulates Milk Fat Metabolism by Targeting Large Tumor Suppressor Kinase 1 (LATS1) in Bovine Mammary Epithelial Cells.
Journal of agricultural and food chemistry
Chen Z,Chu S,Wang X,Sun Y,Xu T,Mao Y,Loor JJ,Yang Z
Wed Oct 09 00:00:00 EDT 2019
MicroRNA-181b-5p modulates tumor necrosis factor-α-induced inflammatory responses by targeting interleukin-6 in cementoblasts.
Journal of cellular physiology
Wang X,Sun H,Liu H,Ma L,Jiang C,Liao H,Xu S,Xiang J,Cao Z
Sun Dec 01 00:00:00 EST 2019
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
PloS one
Dias HB,de Oliveira JR,Donadio MVF,Kimura S
Thu Apr 02 00:00:00 EDT 2020
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Journal of molecular neuroscience : MN
Wang Q,Hu J,Liu Y,Li J,Liu B,Li M,Lou S
Sun Sep 01 00:00:00 EDT 2019
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
Nutrition & metabolism
Xue M,Liang H,Ji X,Liu Y,Ge Y,Hou L,Sun T
Tue Apr 12 00:00:00 EDT 2022
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader.
Pharmacological research
Zhao Y,Zhao C,Lu J,Wu J,Li C,Hu Z,Tian W,Yang L,Xiang J,Zhou H,Deng Z,Huang J,Hong K
Thu Aug 01 00:00:00 EDT 2019
Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang S,Zhou Y,Zhang Y,He X,Zhao X,Zhao H,Liu W
Mon Jul 01 00:00:00 EDT 2019
TUSC3 as a potential biomarker for prognosis in clear cell renal cell carcinoma.
Oncology letters
Yan Y,Chen Z,Liao Y,Zhou J
Sat Jun 01 00:00:00 EDT 2019
Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.
BMC cancer
Xu M,Wang X,Pan Y,Zhao X,Yan B,Ruan C,Xia L,Zhao Y
Mon Jun 17 00:00:00 EDT 2019
LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway.
Frontiers in physiology
Fan M,Li X,Gao X,Dong L,Xin G,Chen L,Qiu J,Xu Y
Thu Oct 01 00:00:00 EDT 2020
Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia.
EBioMedicine
Jiang Y,Zhou J,Zou D,Hou D,Zhang H,Zhao J,Li L,Hu J,Zhang Y,Jing Z
Tue Oct 01 00:00:00 EDT 2019
Leukemia Inhibitory Factor Receptor Is Involved in Apoptosis in Rat Astrocytes Exposed to Oxygen-Glucose Deprivation.
BioMed research international
Huo L,Fan Y,Wang H
Mon Jul 22 00:00:00 EDT 2019
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Biochemical and biophysical research communications
Zhou Z,Dong Y,Zhou H,Liu J,Zhao W
Tue Sep 24 00:00:00 EDT 2019
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Science China. Life sciences
Liu Y,Wang Y,Wang F,Pan J,Xu J,Li J,Zhou C,Ding G,Wu Y,Liu X,Sheng J,Huang H
Fri Feb 01 00:00:00 EST 2019
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu ZH,Zhang Y,Wang X,Fan XF,Zhang Y,Li X,Gong YS,Han LP
Tue Oct 01 00:00:00 EDT 2019
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Toxicology in vitro : an international journal published in association with BIBRA
Zeng N,Zhang Z,Jiang H,Li R,Chang C,Wang F,Xu D,Fan Q,Wang T,Xiao Y,Chen W,Shan Z,Huang Z,Wang Q
Sun Dec 01 00:00:00 EST 2019
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Mediators of inflammation
Guo Y,Huang C,Liu L,Fu X,Lu Y,Zheng J,Mei Q,Huang Z,Fan J,Lu L,Zeng Y
Mon Jun 01 00:00:00 EDT 2020
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
ACS omega
Zhou J,Zheng J,Zhang Y,Zheng P,Tang T,Luo JK,Cui HJ,Song RR,Wang Y
Sun Jun 30 00:00:00 EDT 2019
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
EBioMedicine
Wang T,Fu X,Jin T,Zhang L,Liu B,Wu Y,Xu F,Wang X,Ye K,Zhang W,Ye L
Mon Jul 01 00:00:00 EDT 2019
DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
Pathology, research and practice
Mei J,Huang Y,Hao L,Liu Y,Yan T,Qiu T,Xu R,Xu B,Xiao Z,Jiang X,Hu K,Zhu Y
Mon Jul 01 00:00:00 EDT 2019
Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice.
Journal of agricultural and food chemistry
Sha JY,Zhou YD,Yang JY,Leng J,Li JH,Hu JN,Liu W,Jiang S,Wang YP,Chen C,Li W
Wed Sep 18 00:00:00 EDT 2019
Aptamer-Based Erythrocyte-Derived Mimic Vesicles Loaded with siRNA and Doxorubicin for the Targeted Treatment of Multidrug-Resistant Tumors.
ACS applied materials & interfaces
Wang T,Luo Y,Lv H,Wang J,Zhang Y,Pei R
Wed Dec 11 00:00:00 EST 2019
Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function.
OncoTargets and therapy
Zhou L,Liu L,Chai W,Zhao T,Jin X,Guo X,Han L,Yuan C
Fri Apr 08 00:00:00 EDT 2022
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Li R,Liu Y,Shi J,Yu Y,Lu H,Yu L,Liu Y,Zhang F
Thu Aug 01 00:00:00 EDT 2019
7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.
Life sciences
Zhang E,Liu J,Shi L,Guo X,Liang Z,Zuo J,Xu H,Wang H,Shu X,Huang S,Zhang S,Kang X,Zhen Y
Sun Dec 01 00:00:00 EST 2019
Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.
Molecular immunology
Qian T,Hong J,Wang L,Wang Z,Lu Z,Li Y,Liu R,Chu Y
Mon Jul 01 00:00:00 EDT 2019
Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells.
Frontiers in pharmacology
Wen M,Deng ZK,Jiang SL,Guan YD,Wu HZ,Wang XL,Xiao SS,Zhang Y,Yang JM,Cao DS,Cheng Y
Wed Sep 30 00:00:00 EDT 2020
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
Journal of cellular biochemistry
Chen X,Pan H,Li J,Zhang G,Cheng S,Zuo N,Zhao Q,Peng Z
Tue Oct 01 00:00:00 EDT 2019
Dysregulated Transcription Factor TFAP2A After Peripheral Nerve Injury Modulated Schwann Cell Phenotype.
Neurochemical research
Zhang F,Gu X,Yi S,Xu H
Sun Dec 01 00:00:00 EST 2019
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Marine drugs
Tao W,Sun W,Liu L,Wang G,Xiao Z,Pei X,Wang M
Sat Nov 16 00:00:00 EST 2019
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network.
Aging
Liang Q,Li X,Guan G,Xu X,Chen C,Cheng P,Cheng W,Wu A
Mon Sep 02 00:00:00 EDT 2019
Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway.
American journal of translational research
Lee HC,Yu HP,Liao CC,Chou AH,Liu FC
Thu Oct 01 00:00:00 EDT 2020
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
Biological & pharmaceutical bulletin
Inamura A,Muraoka-Hirayama S,Sakurai K
Thu Apr 09 00:00:00 EDT 2020
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Scientific reports
Qi W,Li Z,Xia L,Dai J,Zhang Q,Wu C,Xu S
Thu Nov 07 00:00:00 EST 2019
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cell adhesion & migration
Cheng Z,Xin H,Han T
Sun Dec 01 00:00:00 EST 2019
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Food & function
Ren D,Zhao Y,Zheng Q,Alim A,Yang X
Mon Apr 01 00:00:00 EDT 2019
Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
Journal of toxicology and environmental health. Part A
Wang L,Pei JH,Jia JX,Wang J,Song W,Fang X,Cai ZP,Huo DS,Wang H,Yang ZJ
Thu May 21 00:00:00 EDT 2020
The Role of Nrf2 Signaling Pathway in Eucommia ulmoides Flavones Regulating Oxidative Stress in the Intestine of Piglets.
Oxidative medicine and cellular longevity
Xiao D,Yuan D,Tan B,Wang J,Liu Y,Tan B
Fri Mar 20 00:00:00 EDT 2020
Tandem repeat sequence of duck circovirus serves as downstream sequence element to regulate viral gene expression.
Veterinary microbiology
Wu ZC,Xia XJ,Li HR,Jiang SJ,Ma ZY,Wang X
Sun Dec 01 00:00:00 EST 2019
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Journal of translational medicine
Lu B,Zhong J,Pan J,Yuan X,Ren M,Jiang L,Yang Y,Zhang G,Liu D,Zhang C
Tue Dec 17 00:00:00 EST 2019
AcMNPV PKIP is associated with nucleocapsid of budded virions and involved in nucleocapsid assembly.
Virus research
Lai Q,Zhu L,Xu L,Yuan M,Wu W,Yang K
Mon Jul 15 00:00:00 EDT 2019
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Diabetes
Mao Z,Lin H,Su W,Li J,Zhou M,Li Z,Zhou B,Yang Q,Zhou M,Pan K,He J,Zhang W
Sat Jun 01 00:00:00 EDT 2019
Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
Aging
Xu W,Zou H,Wei Z,Song C,Tang C,Yin X,Wang Y,Han S,Cai Y,Han W
Thu Jun 06 00:00:00 EDT 2019
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Investigative ophthalmology & visual science
Wang X,Qu M,Li J,Danielson P,Yang L,Zhou Q
Thu Aug 01 00:00:00 EDT 2019
A hidden human proteome encoded by 'non-coding' genes.
Nucleic acids research
Lu S,Zhang J,Lian X,Sun L,Meng K,Chen Y,Sun Z,Yin X,Li Y,Zhao J,Wang T,Zhang G,He QY
Thu Sep 05 00:00:00 EDT 2019
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Biochemical and biophysical research communications
Zhang J,Yao D,Zhang J,Song Y,Mo F,Chu X,Pan Y,Bai Y,Shao C
Sun Jun 30 00:00:00 EDT 2019
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Frontiers in microbiology
Wang Y,Zhao S,Chen Y,Wang T,Dong C,Wo X,Zhang J,Dong Y,Xu W,Feng X,Qu C,Wang Y,Zhong Z,Zhao W
Thu Oct 01 00:00:00 EDT 2020
CDK11p110 plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
Cell cycle (Georgetown, Tex.)
Du Y,Yan D,Yuan Y,Xu J,Wang S,Yang Z,Cheng W,Tian X,Kan Q
Fri Feb 01 00:00:00 EST 2019
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jia B,Wang Y,Yu G,Cheng Y,Yang C,Cao F,He Y,Cao P,Meng X,Yu D
Mon Jul 01 00:00:00 EDT 2019
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Theranostics
Chen Y,Liu P,Sun P,Jiang J,Zhu Y,Dong T,Cui Y,Tian Y,An T,Zhang J,Li Z,Yang X
Fri Jan 31 00:00:00 EST 2020
Zinc alleviates arsenism in common carp: Varied change profiles of cytokines and tight junction proteins among two intestinal segments.
Fish & shellfish immunology
Zhao H,Wang Y,Yang X,Fei D,Mu M,Guo M,Yu H,Xing M
Fri Nov 01 00:00:00 EDT 2019
Xiaoerfupi alleviates the symptoms of functional dyspepsia by regulating the HTR3A and c-FOS.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ji E,Wang T,Guo F,Zhang Y,Tang C,Tang D,Wei J,Yang H,Xian M
Sun Dec 01 00:00:00 EST 2019
AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain.
Journal of Alzheimer's disease : JAD
Xu M,Huang Y,Song P,Huang Y,Huang W,Zhang HT,Hu Y
Thu Oct 01 00:00:00 EDT 2020
The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population.
Genetic testing and molecular biomarkers
Shi Y,Li Y,Wang Y,Zhuang J,Wang H,Hu M,Mo X,Yue S,Chen Y,Fan X,Chen J,Cai W,Zhu X,Wan Y,Zhong Y,Ye X,Li F,Zhou Z,Dai G,Luo R,Ocorr K,Jiang Z,Li X,Zhu P,Wu X,Yuan W
Sun Sep 01 00:00:00 EDT 2019
Zearalenone Induces Estrogen-Receptor-Independent Neutrophil Extracellular Trap Release in Vitro.
Journal of agricultural and food chemistry
Wang JJ,Wei ZK,Han Z,Liu ZY,Zhu XY,Li XW,Wang K,Yang ZT
Wed Apr 24 00:00:00 EDT 2019
An NF90/long noncoding RNA-LET/miR-548k feedback amplification loop controls esophageal squamous cell carcinoma progression.
Journal of Cancer
Lin J,Chen Z,Wu S,Huang W,Chen F,Huang Z
Wed Sep 30 00:00:00 EDT 2020
Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway.
Proteomics
Chen YY,Wen SY,Deng CM,Yin XF,Sun ZH,Jiang MM,He QY
Thu Aug 01 00:00:00 EDT 2019
N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells.
Oxidative medicine and cellular longevity
Chu Q,Zhang Y,Zhong S,Gao F,Chen Y,Wang B,Zhang Z,Cai W,Li W,Zheng F,Shi G
Thu Jan 09 00:00:00 EST 2020
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Frontiers in molecular neuroscience
Chang HY,Cheng HY,Tsao AN,Liu C,Tsai JW
Tue Sep 29 00:00:00 EDT 2020
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity.
Cancer immunology research
Huang X,Zhang Q,Lou Y,Wang J,Zhao X,Wang L,Zhang X,Li S,Zhao Y,Chen Q,Liang T,Bai X
Tue Oct 01 00:00:00 EDT 2019
UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhong X,He J,Zhang X,Li C,Tian X,Xia W,Gan H,Xia Y
Mon Jul 01 00:00:00 EDT 2019
Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage.
Frontiers in neuroscience
Li G,Yu H,Liu N,Zhang P,Tang Y,Hu Y,Zhang Y,Pan C,Deng H,Wang J,Li Q,Tang Z
Thu Oct 01 00:00:00 EDT 2020
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
International journal of biological sciences
Ma L,Wang X,Liu H,Jiang C,Liao H,Xu S,Guo Y,Cao Z
Mon Apr 06 00:00:00 EDT 2020
ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cao X,Chen J,Li D,Xie P,Xu M,Lin W,Li S,Pan G,Tang Y,Xu J,Olkkonen VM,Yan D,Zhong W
Sun Dec 01 00:00:00 EST 2019
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Journal of cellular and molecular medicine
Yan XY,Zhong XR,Yu SH,Zhang LC,Liu YN,Zhang Y,Sun LK,Su J
Sat Jun 01 00:00:00 EDT 2019
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.
Toxicology
Yang X,Zhang X,Liu Y,Xi T,Xiong J
Sat Jun 15 00:00:00 EDT 2019
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Journal of neurosurgery
Yu G,Liu P,Shi Y,Li S,Liu Y,Fan Z,Zhu W
Fri Aug 09 00:00:00 EDT 2019
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
British journal of pharmacology
Zhang J,Bi R,Meng Q,Wang C,Huo X,Liu Z,Wang C,Sun P,Sun H,Ma X,Wu J,Liu K
Sun Dec 01 00:00:00 EST 2019
Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.
Molecular & cellular proteomics : MCP
Hartel NG,Chew B,Qin J,Xu J,Graham NA
Fri Nov 01 00:00:00 EDT 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 EDT 2019
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
FEBS open bio
Tashakor A,H-Dehkordi M,O'Connell E,Gomez Ganau S,Gozalbes R,Eriksson LA,Hosseinkhani S,Fearnhead HO
Mon Jul 01 00:00:00 EDT 2019
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Journal of hematology & oncology
Hua Q,Jin M,Mi B,Xu F,Li T,Zhao L,Liu J,Huang G
Thu Sep 05 00:00:00 EDT 2019
Macrophage migration inhibitory factor facilitates prostaglandin E2 production of astrocytes to tune inflammatory milieu following spinal cord injury.
Journal of neuroinflammation
Zhang Y,Zhou Y,Chen S,Hu Y,Zhu Z,Wang Y,Du N,Song T,Yang Y,Guo A,Wang Y
Sat Apr 13 00:00:00 EDT 2019
Mechanosensitive ion channel Piezo1 promotes prostate cancer development through the activation of the Akt/mTOR pathway and acceleration of cell cycle.
International journal of oncology
Han Y,Liu C,Zhang D,Men H,Huo L,Geng Q,Wang S,Gao Y,Zhang W,Zhang Y,Jia Z
Sun Sep 01 00:00:00 EDT 2019
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL-6-STAT3 pathway.
Molecular oncology
Wang J,Zhou J,Jiang C,Zheng J,Namba H,Chi P,Asakawa T
Fri Nov 01 00:00:00 EDT 2019
miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2.
Cancer cell international
Peng CW,Yue LX,Zhou YQ,Tang S,Kan C,Xia LM,Yang F,Wang SY
Tue Apr 12 00:00:00 EDT 2022
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Nature chemical biology
Spradlin JN,Hu X,Ward CC,Brittain SM,Jones MD,Ou L,To M,Proudfoot A,Ornelas E,Woldegiorgis M,Olzmann JA,Bussiere DE,Thomas JR,Tallarico JA,McKenna JM,Schirle M,Maimone TJ,Nomura DK
Mon Jul 01 00:00:00 EDT 2019
Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism.
Molecular medicine reports
Zhang Z,Wang J,Zhu Y,Zhang H,Wang H
Fri Nov 01 00:00:00 EDT 2019
Clinical roles of miR-136-5p and its target metadherin in thyroid carcinoma.
American journal of translational research
Gao RZ,Que Q,Lin P,Pang YY,Wu HY,Li XJ,Chen G,He Y,Yang H
Mon Sep 28 00:00:00 EDT 2020
Expression Of BMP7 In Ovarian Cancer And Biological Effect Of BMP7 Knockdown On Ovarian Cancer Cells.
OncoTargets and therapy
Guan H,Li J,Sun R,Liu W,Feng M,Ma H,Li C
Sun Apr 10 00:00:00 EDT 2022
Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model.
Oxidative medicine and cellular longevity
Li Y,Hou S,Peng W,Lin Q,Chen F,Yang L,Li F,Huang X
Tue Apr 23 00:00:00 EDT 2019
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Frontiers in immunology
Zong X,Cao X,Wang H,Xiao X,Wang Y,Lu Z
Mon Sep 28 00:00:00 EDT 2020
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Acta biomaterialia
Huang Q,Ouyang Z,Tan Y,Wu H,Liu Y
Sun Dec 01 00:00:00 EST 2019
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Life science alliance
Tian S,Feng J,Cao Y,Shen S,Cai Y,Yang D,Yan R,Wang L,Zhang H,Zhong X,Gao P
Tue Oct 01 00:00:00 EDT 2019
MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway.
Molecular and cellular biochemistry
Sun L,Li Z,Xue H,Ma T,Ren C,Li M,Lu Y,Sun H,Zhang K
Tue Oct 01 00:00:00 EDT 2019
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Cell death & disease
Guo T,Liu T,Sun Y,Liu X,Xiong R,Li H,Li Z,Zhang Z,Tian Z,Tian Y
Tue Jun 11 00:00:00 EDT 2019
17β‑Estradiol protects against interleukin‑1β‑induced apoptosis in rat nucleus pulposus cells via the mTOR/caspase‑3 pathway.
Molecular medicine reports
Guo HT,Yang SD,Zhang F,Liu S,Yang DL,Ma L,Wang H,Ding WY
Thu Aug 01 00:00:00 EDT 2019
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Molecular pharmaceutics
Li C,Luo J,Guo S,Jia X,Guo C,Li X,Xu Q,Shi D
Mon May 06 00:00:00 EDT 2019
RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu X,Yang Y,Xu C,Yang H,Chen S,Chen H
Tue Oct 01 00:00:00 EDT 2019
Lysine glutarylation in human sperm is associated with progressive motility.
Human reproduction (Oxford, England)
Cheng YM,Hu XN,Peng Z,Pan TT,Wang F,Chen HY,Chen WQ,Zhang Y,Zeng XH,Luo T
Mon Jul 08 00:00:00 EDT 2019
Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.
International endodontic journal
Qiao W,Huang Y,Bian Z,Sun X,Wang X,Gao Q,Peng Y,Meng L
Sun Dec 01 00:00:00 EST 2019
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.
Evidence-based complementary and alternative medicine : eCAM
Guo Y,Pei X
Sun Apr 10 00:00:00 EDT 2022
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Journal of molecular biology
Tikhonova EB,Karamysheva ZN,von Heijne G,Karamyshev AL
Fri Jun 28 00:00:00 EDT 2019
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Frontiers in microbiology
Gao J,Li Y,Wan Y,Hu T,Liu L,Yang S,Gong Z,Zeng Q,Wei Y,Yang W,Zeng Z,He X,Huang SH,Cao H
Wed Sep 30 00:00:00 EDT 2020
Abnormal expression of Pappa2 gene may indirectly affect mouse hip development through the IGF signaling pathway.
Endocrine
Chen Y,Li L,Wang E,Zhang L,Zhao Q
Thu Aug 01 00:00:00 EDT 2019
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
eLife
Pan T,Song Z,Wu L,Liu G,Ma X,Peng Z,Zhou M,Liang L,Liu B,Liu J,Zhang J,Zhang X,Huang R,Zhao J,Li Y,Ling X,Luo Y,Tang X,Cai W,Deng K,Li L,Zhang H
Fri Aug 09 00:00:00 EDT 2019
Prepartum body conditions affect insulin signaling pathways in postpartum adipose tissues in transition dairy cows.
Journal of animal science and biotechnology
Zhang F,Li D,Wu Q,Sun J,Guan W,Hou Y,Zhu Y,Wang J
Fri Apr 08 00:00:00 EDT 2022
Regulation of macrophage iron homeostasis is associated with the localization of bacteria.
Metallomics : integrated biometal science
Gan Z,Tang X,Wang Z,Li J,Wang Z,Du H
Wed Feb 20 00:00:00 EST 2019
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2.
OncoTargets and therapy
Sun J,Niu L,Gao S,Yi X,Chen J
Mon Apr 11 00:00:00 EDT 2022
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.
American journal of nephrology
Wang C,Ye M,Zhao Q,Xia M,Liu D,He L,Chen G,Peng Y,Liu H
Wed May 27 00:00:00 EDT 2020
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Biochemical and biophysical research communications
Zhu Y,Shao Y,Qu X,Guo J,Yang J,Zhou Z,Wang S
Tue May 14 00:00:00 EDT 2019
MicroRNA-106b Regulates Milk Fat Metabolism via ATP Binding Cassette Subfamily A Member 1 ( ABCA1) in Bovine Mammary Epithelial Cells.
Journal of agricultural and food chemistry
Chen Z,Chu S,Wang X,Fan Y,Zhan T,Arbab AAI,Li M,Zhang H,Mao Y,Loor JJ,Yang Z
Wed Apr 10 00:00:00 EDT 2019
MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway.
The FEBS journal
Wang HT,Tong X,Zhang ZX,Sun YY,Yan W,Xu ZM,Fu WN
Tue Oct 01 00:00:00 EDT 2019
MiR-302a-5p suppresses cell proliferation and invasion in non-small cell lung carcinoma by targeting ITGA6.
American journal of translational research
Chen W,Zhuang X,Qi R,Qiao T
Thu Oct 01 00:00:00 EDT 2020
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
Frontiers in immunology
Li C,Liu J,Zhang X,Wei S,Huang X,Huang Y,Wei J,Qin Q
Wed Sep 09 00:00:00 EDT 2020
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.
The Journal of biological chemistry
Delfarah A,Parrish S,Junge JA,Yang J,Seo F,Li S,Mac J,Wang P,Fraser SE,Graham NA
Fri Jul 05 00:00:00 EDT 2019
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
European journal of pharmacology
Chen K,Wei H,Pan J,Chen Z,Pan D,Gao T,Huang J,Huang M,Ou M,Zhong W
Tue Oct 15 00:00:00 EDT 2019
The Pseudogene PTTG3P Promotes Cell Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Open medicine (Warsaw, Poland)
Zhang Z,Shi Z
Wed Sep 30 00:00:00 EDT 2020
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
International immunopharmacology
Sun LJ,Qiao W,Xiao YJ,Cui L,Wang X,Ren WD
Tue Oct 01 00:00:00 EDT 2019
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Biochimica et biophysica acta. Molecular cell research
Yang Q,Fan W,Zheng Z,Lin S,Liu C,Wang R,Li W,Zuo Y,Sun Y,Hu S,Chen M,Guo P,Pan J,Tian C,Zhu T,Diao C,Hao J,Yu W,Li L,Li Y,Guo W,Deng W,Wu X
Tue Oct 01 00:00:00 EDT 2019
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.
Neuropharmacology
Huang HJ,Chen XR,Han QQ,Wang J,Pilot A,Yu R,Liu Q,Li B,Wu GC,Wang YQ,Yu J
Sun Sep 01 00:00:00 EDT 2019
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Scientific reports
Martin-Hurtado A,Martin-Morales R,Robledinos-Antón N,Blanco R,Palacios-Blanco I,Lastres-Becker I,Cuadrado A,Garcia-Gonzalo FR
Wed Sep 25 00:00:00 EDT 2019
O-GlcNAcylation of Thr12/Ser56 in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
The Journal of biological chemistry
Liu L,Li L,Ma C,Shi Y,Liu C,Xiao Z,Zhang Y,Tian F,Gao Y,Zhang J,Ying W,Wang PG,Zhang L
Fri Nov 08 00:00:00 EST 2019
Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway.
Experimental and therapeutic medicine
Guo G,Tian A,Lan X,Fu C,Yan Z,Wang C
Wed May 01 00:00:00 EDT 2019
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Frontiers in oncology
Jin H,Liu P,Kong L,Fei X,Gao Y,Wu T,Sun D,Tan X
Wed Sep 30 00:00:00 EDT 2020
Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.
Frontiers in oncology
Liu X,Zhao P,Wang X,Wang L,Zhu Y,Gao W
Thu Oct 01 00:00:00 EDT 2020
Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.
Medical science monitor : international medical journal of experimental and clinical research
Kang M,Shao S,Zhang Y,Liang X,Zhang K,Li G
Sat Dec 21 00:00:00 EST 2019
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment.
Cell death & disease
Qi D,Wei M,Jiao S,Song Y,Wang X,Xie G,Taranto J,Liu Y,Duan Y,Yu B,Li H,Shah YM,Xu Q,Du J,Gonzalez FJ,Qu A
Thu Jul 18 00:00:00 EDT 2019
Arsenic sulfide induces miR-4665-3p to inhibit gastric cancer cell invasion and migration.
Drug design, development and therapy
Zhang X,Tan Z,Kang T,Zhu C,Chen S
Mon Mar 30 00:00:00 EDT 2020
Lingguizhugan decoction attenuates diet-induced obesity and hepatosteatosis via gut microbiota.
World journal of gastroenterology
Liu MT,Huang YJ,Zhang TY,Tan LB,Lu XF,Qin J
Sun Jul 21 00:00:00 EDT 2019
Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway.
Oncology letters
Zhai XH,Xiao J,Yu JK,Sun H,Zheng S
Sun Dec 01 00:00:00 EST 2019
Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro.
Acta pharmacologica Sinica
Yu P,Wang HY,Tian M,Li AX,Chen XS,Wang XL,Zhang Y,Cheng Y
Sun Sep 01 00:00:00 EDT 2019
Dietary canolol induces apoptosis in human cervical carcinoma HeLa cells through ROS-MAPK mediated mitochondrial signaling pathway: In vitro and in vivo.
Chemico-biological interactions
Xia X,Xiang X,Huang F,Zheng M,Zhang Z,Han L
Mon Feb 25 00:00:00 EST 2019
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Stem cells international
Rao N,Wang X,Xie J,Li J,Zhai Y,Li X,Fang T,Wang Y,Zhao Y,Ge L
Thu Oct 01 00:00:00 EDT 2020
Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.
Applied microbiology and biotechnology
Wang Z,Song P,Li Y,Wang S,Fan J,Zhang X,Luan J,Chen W,Wang Y,Liu P,Ju D
Sat Jun 01 00:00:00 EDT 2019
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Biochemical and biophysical research communications
Chen J,Liang B,Bian D,Luo Y,Yang J,Li Z,Zhuang Z,Zang S,Shi J
Tue Oct 22 00:00:00 EDT 2019
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Journal of Cancer
Liu K,Du S,Gao P,Zheng J
Thu Oct 01 00:00:00 EDT 2020
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Medrano G,Cailleux F,Guan P,Kuruvilla K,Barlow-Anacker AJ,Gosain A
Sat Jun 01 00:00:00 EDT 2019
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
The Biochemical journal
Kojima T,Funato Y,Miki H
Tue May 21 00:00:00 EDT 2019
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Journal of medicinal food
Luo J,Long Y,Ren G,Zhang Y,Chen J,Huang R,Yang L
Sun Dec 01 00:00:00 EST 2019
Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.
Frontiers in physiology
He J,Ding J,Lai Q,Wang X,Li A,Liu S
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows.
Reproduction in domestic animals = Zuchthygiene
Chen Z,Xu X,Tan T,Chen D,Liang H,Sun K,Li M,Zhang H,Mao Y,Yang Z
Sat Jun 01 00:00:00 EDT 2019
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Cancer letters
Hu Q,Qin Y,Ji S,Xu W,Liu W,Sun Q,Zhang Z,Liu M,Ni Q,Yu X,Xu X
Fri Jun 28 00:00:00 EDT 2019
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
Journal of Cancer
Chen H,Liu J,Wang H,Cheng Q,Zhou C,Chen X,Ye F
Thu Oct 01 00:00:00 EDT 2020
Curcumin and Curcumol Inhibit NF-κB and TGF-β 1/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells.
Evidence-based complementary and alternative medicine : eCAM
Li N,Liu TH,Yu JZ,Li CX,Liu Y,Wu YY,Yang ZS,Yuan JL
Tue Sep 29 00:00:00 EDT 2020
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Molecular biology reports
Chen X,Li H,Yang Q,Lan X,Wang J,Cao Z,Shi X,Li J,Kan M,Qu X,Li N
Tue Oct 01 00:00:00 EDT 2019
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Nature communications
Urdaneta EC,Vieira-Vieira CH,Hick T,Wessels HH,Figini D,Moschall R,Medenbach J,Ohler U,Granneman S,Selbach M,Beckmann BM
Fri Mar 01 00:00:00 EST 2019
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Bioscience, biotechnology, and biochemistry
Liu Y,Kanyomse Q,Xie Y
Fri Nov 01 00:00:00 EDT 2019
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Chemico-biological interactions
Wu XY,Chen XM,Zhou MX,Hu HX,Zhang JZ,Wang XN,Ren DM,Lou HX,Shen T
Sun Sep 01 00:00:00 EDT 2019
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
OncoTargets and therapy
Qian S,Tan X,Liu X,Liu P,Wu Y
Mon Oct 24 00:00:00 EDT 2022
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Cell
Karki R,Lee E,Place D,Samir P,Mavuluri J,Sharma BR,Balakrishnan A,Malireddi RKS,Geiger R,Zhu Q,Neale G,Kanneganti TD
Thu May 03 00:00:00 EDT 2018
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Cell
Karki R,Lee E,Place D,Samir P,Mavuluri J,Sharma BR,Balakrishnan A,Malireddi RKS,Geiger R,Zhu Q,Neale G,Kanneganti TD
Thu May 03 00:00:00 EDT 2018
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Cell
Huang X,Yan J,Zhang M,Wang Y,Chen Y,Fu X,Wei R,Zheng XL,Liu Z,Zhang X,Yang H,Hao B,Shen YY,Su Y,Cong X,Huang M,Tan M,Ding J,Geng M
Thu Sep 20 00:00:00 EDT 2018
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Cell
Huang X,Yan J,Zhang M,Wang Y,Chen Y,Fu X,Wei R,Zheng XL,Liu Z,Zhang X,Yang H,Hao B,Shen YY,Su Y,Cong X,Huang M,Tan M,Ding J,Geng M
Thu Sep 20 00:00:00 EDT 2018
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
Nature cell biology
Ying Z,Sandoval M,Beronja S
Thu Nov 01 00:00:00 EDT 2018
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
Nature cell biology
Ying Z,Sandoval M,Beronja S
Thu Nov 01 00:00:00 EDT 2018
PTEN-L promotes type I interferon responses and antiviral immunity.
Cellular & molecular immunology
Cao Y,Wang H,Yang L,Zhang Z,Li C,Yuan X,Bu L,Chen L,Chen Y,Li CM,Guo D
Mon Jan 01 00:00:00 EST 2018
PTEN-L promotes type I interferon responses and antiviral immunity.
Cellular & molecular immunology
Cao Y,Wang H,Yang L,Zhang Z,Li C,Yuan X,Bu L,Chen L,Chen Y,Li CM,Guo D
Mon Jan 01 00:00:00 EST 2018
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Brain, behavior, and immunity
Balan I,Warnock KT,Puche A,Gondre-Lewis MC,Aurelian L
Thu Mar 01 00:00:00 EST 2018
Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity.
Brain, behavior, and immunity
Balan I,Warnock KT,Puche A,Gondre-Lewis MC,Aurelian L
Thu Mar 01 00:00:00 EST 2018
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Metabolism: clinical and experimental
Wu R,Liu X,Yin J,Wu H,Cai X,Wang N,Qian Y,Wang F
Fri Jun 01 00:00:00 EDT 2018
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Metabolism: clinical and experimental
Wu R,Liu X,Yin J,Wu H,Cai X,Wang N,Qian Y,Wang F
Fri Jun 01 00:00:00 EDT 2018
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhong Q,Liu ZH,Lin ZR,Hu ZD,Yuan L,Liu YM,Zhou AJ,Xu LH,Hu LJ,Wang ZF,Guan XY,Hao JJ,Lui VWY,Guo L,Mai HQ,Chen MY,Han F,Xia YF,Grandis JR,Zhang X,Zeng MS
Thu Feb 01 00:00:00 EST 2018
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhong Q,Liu ZH,Lin ZR,Hu ZD,Yuan L,Liu YM,Zhou AJ,Xu LH,Hu LJ,Wang ZF,Guan XY,Hao JJ,Lui VWY,Guo L,Mai HQ,Chen MY,Han F,Xia YF,Grandis JR,Zhang X,Zeng MS
Thu Feb 01 00:00:00 EST 2018
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Developmental cell
Zhang X,Wang L,Lak B,Li J,Jokitalo E,Wang Y
Mon Apr 23 00:00:00 EDT 2018
GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.
Developmental cell
Zhang X,Wang L,Lak B,Li J,Jokitalo E,Wang Y
Mon Apr 23 00:00:00 EDT 2018
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Autophagy
Han T,Guo M,Gan M,Yu B,Tian X,Wang JB
Tue Oct 22 00:00:00 EDT 2019
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Autophagy
Han T,Guo M,Gan M,Yu B,Tian X,Wang JB
Tue Oct 22 00:00:00 EDT 2019
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Journal of cachexia, sarcopenia and muscle
Gorski T,Mathes S,Krützfeldt J
Sun Apr 01 00:00:00 EDT 2018
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Journal of cachexia, sarcopenia and muscle
Gorski T,Mathes S,Krützfeldt J
Sun Apr 01 00:00:00 EDT 2018
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Pharmacological research
Yan J,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Sun H
Sun Apr 01 00:00:00 EDT 2018
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Pharmacological research
Yan J,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Sun H
Sun Apr 01 00:00:00 EDT 2018
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Pharmacological research
Zhao H,Wang Z,Tang F,Zhao Y,Feng D,Li Y,Hu Y,Wang C,Zhou J,Tian X,Yao J
Thu Feb 01 00:00:00 EST 2018
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Pharmacological research
Zhao H,Wang Z,Tang F,Zhao Y,Feng D,Li Y,Hu Y,Wang C,Zhou J,Tian X,Yao J
Thu Feb 01 00:00:00 EST 2018
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Cancer letters
Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S
Sun Apr 01 00:00:00 EDT 2018
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Cancer letters
Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S
Sun Apr 01 00:00:00 EDT 2018
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
British journal of cancer
Ma H,Jin S,Yang W,Zhou G,Zhao M,Fang S,Zhang Z,Hu J
Tue Feb 20 00:00:00 EST 2018
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
British journal of cancer
Ma H,Jin S,Yang W,Zhou G,Zhao M,Fang S,Zhang Z,Hu J
Tue Feb 20 00:00:00 EST 2018
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
EMBO reports
Ge G,Peng D,Xu Z,Guan B,Xin Z,He Q,Zhou Y,Li X,Zhou L,Ci W
Wed Aug 01 00:00:00 EDT 2018
Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth.
EMBO reports
Ge G,Peng D,Xu Z,Guan B,Xin Z,He Q,Zhou Y,Li X,Zhou L,Ci W
Wed Aug 01 00:00:00 EDT 2018
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Frontiers in immunology
Li C,Du S,Tian M,Wang Y,Bai J,Tan P,Liu W,Yin R,Wang M,Jiang Y,Li Y,Zhu N,Zhu Y,Li T,Wu S,Jin N,He F
Fri Mar 29 00:00:00 EDT 2019
The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection.
Frontiers in immunology
Li C,Du S,Tian M,Wang Y,Bai J,Tan P,Liu W,Yin R,Wang M,Jiang Y,Li Y,Zhu N,Zhu Y,Li T,Wu S,Jin N,He F
Fri Mar 29 00:00:00 EDT 2019
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Frontiers in immunology
Tian Y,Feng H,Han L,Wu L,Lv H,Shen B,Li Z,Zhang Q,Liu G
Thu Mar 07 00:00:00 EST 2019
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Frontiers in immunology
Tian Y,Feng H,Han L,Wu L,Lv H,Shen B,Li Z,Zhang Q,Liu G
Thu Mar 07 00:00:00 EST 2019
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Cell proliferation
Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y
Wed Aug 01 00:00:00 EDT 2018
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Cell proliferation
Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y
Wed Aug 01 00:00:00 EDT 2018
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Journal of molecular cell biology
Xu X,Shi R,Zheng L,Guo Z,Wang L,Zhou M,Zhao Y,Tian B,Truong K,Chen Y,Shen B,Hua Y,Xu H
Mon Oct 01 00:00:00 EDT 2018
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Journal of molecular cell biology
Xu X,Shi R,Zheng L,Guo Z,Wang L,Zhou M,Zhao Y,Tian B,Truong K,Chen Y,Shen B,Hua Y,Xu H
Mon Oct 01 00:00:00 EDT 2018
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Free radical biology & medicine
Zhuang W,Li T,Wang C,Shi X,Li Y,Zhang S,Zhao Z,Dong H,Qiao Y
Fri Jun 01 00:00:00 EDT 2018
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis.
Free radical biology & medicine
Zhuang W,Li T,Wang C,Shi X,Li Y,Zhang S,Zhao Z,Dong H,Qiao Y
Fri Jun 01 00:00:00 EDT 2018
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
PLoS pathogens
Zhang L,Liu J,Qian L,Feng Q,Wang X,Yuan Y,Zuo Y,Cheng Q,Miao Y,Guo T,Zheng X,Zheng H
Tue May 01 00:00:00 EDT 2018
Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.
PLoS pathogens
Zhang L,Liu J,Qian L,Feng Q,Wang X,Yuan Y,Zuo Y,Cheng Q,Miao Y,Guo T,Zheng X,Zheng H
Tue May 01 00:00:00 EDT 2018
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
Clinical epigenetics
Peng D,Ge G,Gong Y,Zhan Y,He S,Guan B,Li Y,Xu Z,Hao H,He Z,Xiong G,Zhang C,Shi Y,Zhou Y,Ci W,Li X,Zhou L
Fri Jul 13 00:00:00 EDT 2018
Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer.
Clinical epigenetics
Peng D,Ge G,Gong Y,Zhan Y,He S,Guan B,Li Y,Xu Z,Hao H,He Z,Xiong G,Zhang C,Shi Y,Zhou Y,Ci W,Li X,Zhou L
Fri Jul 13 00:00:00 EDT 2018
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
European journal of medicinal chemistry
Zhou P,Liang Y,Zhang H,Jiang H,Feng K,Xu P,Wang J,Wang X,Ding K,Luo C,Liu M,Wang Y
Sat Jan 20 00:00:00 EST 2018
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
European journal of medicinal chemistry
Zhou P,Liang Y,Zhang H,Jiang H,Feng K,Xu P,Wang J,Wang X,Ding K,Luo C,Liu M,Wang Y
Sat Jan 20 00:00:00 EST 2018
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Clinical science (London, England : 1979)
Wang S,Li J,Wu S,Cheng L,Shen Y,Ma W,She W,Yang C,Wang J,Jiang W
Fri Dec 21 00:00:00 EST 2018
Type 3 innate lymphoid cell: a new player in liver fibrosis progression.
Clinical science (London, England : 1979)
Wang S,Li J,Wu S,Cheng L,Shen Y,Ma W,She W,Yang C,Wang J,Jiang W
Fri Dec 21 00:00:00 EST 2018
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Development (Cambridge, England)
Mastromina I,Verrier L,Silva JC,Storey KG,Dale JK
Mon Jul 30 00:00:00 EDT 2018
Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Development (Cambridge, England)
Mastromina I,Verrier L,Silva JC,Storey KG,Dale JK
Mon Jul 30 00:00:00 EDT 2018
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Life sciences
Huang J,Chen S,Cai D,Bian D,Wang F
Fri Jun 15 00:00:00 EDT 2018
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Life sciences
Huang J,Chen S,Cai D,Bian D,Wang F
Fri Jun 15 00:00:00 EDT 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Cancer science
Sun S,Zhao S,Yang Q,Wang W,Cai E,Wen Y,Yu L,Wang Z,Cai J
Fri Jun 01 00:00:00 EDT 2018
Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Cancer science
Sun S,Zhao S,Yang Q,Wang W,Cai E,Wen Y,Yu L,Wang Z,Cai J
Fri Jun 01 00:00:00 EDT 2018
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Cancer science
Jin H,Liu P,Wu Y,Meng X,Wu M,Han J,Tan X
Sat Sep 01 00:00:00 EDT 2018
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Cancer science
Jin H,Liu P,Wu Y,Meng X,Wu M,Han J,Tan X
Sat Sep 01 00:00:00 EDT 2018
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Journal of cellular physiology
Xie W,Lu Q,Wang K,Lu J,Gu X,Zhu D,Liu F,Guo Z
Sat Sep 01 00:00:00 EDT 2018
miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin.
Journal of cellular physiology
Xie W,Lu Q,Wang K,Lu J,Gu X,Zhu D,Liu F,Guo Z
Sat Sep 01 00:00:00 EDT 2018
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Nanomedicine : nanotechnology, biology, and medicine
Liu DZ,Cheng Y,Cai RQ,Wang Bd WW,Cui H,Liu M,Zhang BL,Mei QB,Zhou SY
Sun Apr 01 00:00:00 EDT 2018
The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.
Nanomedicine : nanotechnology, biology, and medicine
Liu DZ,Cheng Y,Cai RQ,Wang Bd WW,Cui H,Liu M,Zhang BL,Mei QB,Zhou SY
Sun Apr 01 00:00:00 EDT 2018
RNF126 Quenches RNF168 Function in the DNA Damage Response.
Genomics, proteomics & bioinformatics
Zhang L,Wang Z,Shi R,Zhu X,Zhou J,Peng B,Xu X
Sat Dec 01 00:00:00 EST 2018
RNF126 Quenches RNF168 Function in the DNA Damage Response.
Genomics, proteomics & bioinformatics
Zhang L,Wang Z,Shi R,Zhu X,Zhou J,Peng B,Xu X
Sat Dec 01 00:00:00 EST 2018
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Food & function
Gao X,Wang C,Ning C,Liu K,Wang X,Liu Z,Sun H,Ma X,Sun P,Meng Q
Wed May 23 00:00:00 EDT 2018
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Food & function
Gao X,Wang C,Ning C,Liu K,Wang X,Liu Z,Sun H,Ma X,Sun P,Meng Q
Wed May 23 00:00:00 EDT 2018
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
Neural regeneration research
Zhang WY,Wang KY,Li YJ,Li YR,Lu RZ
Sun Jul 01 00:00:00 EDT 2018
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium.
Neural regeneration research
Zhang WY,Wang KY,Li YJ,Li YR,Lu RZ
Sun Jul 01 00:00:00 EDT 2018
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
Frontiers in endocrinology
Liu X,Wang J,Gao L,Jiao Y,Liu C
Wed Nov 20 00:00:00 EST 2019
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.
Frontiers in endocrinology
Liu X,Wang J,Gao L,Jiao Y,Liu C
Wed Nov 20 00:00:00 EST 2019
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
American journal of cancer research
Ye T,Jiang K,Wei L,Barr MP,Xu Q,Zhang G,Ding C,Meng S,Piao H
Tue Jan 05 00:00:00 EST 2021
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
American journal of cancer research
Ye T,Jiang K,Wei L,Barr MP,Xu Q,Zhang G,Ding C,Meng S,Piao H
Tue Jan 05 00:00:00 EST 2021
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
American journal of cancer research
Pan B,Zang J,He J,Wang Z,Liu L
Wed Mar 30 00:00:00 EDT 2022
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
American journal of cancer research
Pan B,Zang J,He J,Wang Z,Liu L
Wed Mar 30 00:00:00 EDT 2022
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Journal of agricultural and food chemistry
Jiao J,Wu J,Wang M,Zhou C,Zhong R,Tan Z
Wed Jan 31 00:00:00 EST 2018
Rhubarb Supplementation Promotes Intestinal Mucosal Innate Immune Homeostasis through Modulating Intestinal Epithelial Microbiota in Goat Kids.
Journal of agricultural and food chemistry
Jiao J,Wu J,Wang M,Zhou C,Zhong R,Tan Z
Wed Jan 31 00:00:00 EST 2018
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Journal of agricultural and food chemistry
Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z
Wed Nov 14 00:00:00 EST 2018
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Journal of agricultural and food chemistry
Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z
Wed Nov 14 00:00:00 EST 2018
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
International journal of oncology
Tang G,Guo J,Zhu Y,Huang Z,Liu T,Cai J,Yu L,Wang Z
Fri Jun 01 00:00:00 EDT 2018
Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation.
International journal of oncology
Tang G,Guo J,Zhu Y,Huang Z,Liu T,Cai J,Yu L,Wang Z
Fri Jun 01 00:00:00 EDT 2018
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang Y,Qi Q,Wang Y,Shi Y,Yang W,Cen Y,Zhu E,Li X,Chen D,Wang B
Fri Jun 01 00:00:00 EDT 2018
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang Y,Qi Q,Wang Y,Shi Y,Yang W,Cen Y,Zhu E,Li X,Chen D,Wang B
Fri Jun 01 00:00:00 EDT 2018
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Wei P,Zheng Q,Liu H,Wan T,Zhou J,Li D,Zhou H,Li J,Ji F,Tang W,Li J
Tue Mar 06 00:00:00 EST 2018
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Wei P,Zheng Q,Liu H,Wan T,Zhou J,Li D,Zhou H,Li J,Ji F,Tang W,Li J
Tue Mar 06 00:00:00 EST 2018
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Frontiers in aging neuroscience
Liu Y,Li R,Xie J,Hu J,Huang X,Ren F,Li L
Tue Sep 29 00:00:00 EDT 2020
Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice.
Frontiers in aging neuroscience
Liu Y,Li R,Xie J,Hu J,Huang X,Ren F,Li L
Tue Sep 29 00:00:00 EDT 2020
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Experimental neurology
Yang L,Tucker D,Dong Y,Wu C,Lu Y,Li Y,Zhang J,Liu TC,Zhang Q
Mon Jan 01 00:00:00 EST 2018
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Experimental neurology
Yang L,Tucker D,Dong Y,Wu C,Lu Y,Li Y,Zhang J,Liu TC,Zhang Q
Mon Jan 01 00:00:00 EST 2018
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Journal of molecular medicine (Berlin, Germany)
Jin S,Ma H,Yang W,Ju H,Wang L,Zhang Z
Fri Jun 01 00:00:00 EDT 2018
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Journal of molecular medicine (Berlin, Germany)
Jin S,Ma H,Yang W,Ju H,Wang L,Zhang Z
Fri Jun 01 00:00:00 EDT 2018
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cheng B,Lu J,Li T,Meng Z,Liu M,Sun M,Guan S
Sat Dec 01 00:00:00 EST 2018
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cheng B,Lu J,Li T,Meng Z,Liu M,Sun M,Guan S
Sat Dec 01 00:00:00 EST 2018
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Laboratory investigation; a journal of technical methods and pathology
Xu J,Wang J,He M,Han H,Xie W,Wang H,Kong H
Mon Oct 01 00:00:00 EDT 2018
Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension.
Laboratory investigation; a journal of technical methods and pathology
Xu J,Wang J,He M,Han H,Xie W,Wang H,Kong H
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Mechanisms of ageing and development
Xing SS,Li J,Chen L,Yang YF,He PL,Li J,Yang J
Mon Oct 01 00:00:00 EDT 2018
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Journal of immunology (Baltimore, Md. : 1950)
Tartey S,Gurung P,Samir P,Burton A,Kanneganti TD
Sat Sep 15 00:00:00 EDT 2018
Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.
Journal of immunology (Baltimore, Md. : 1950)
Tartey S,Gurung P,Samir P,Burton A,Kanneganti TD
Sat Sep 15 00:00:00 EDT 2018
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Proteomics
Zhang N,Gao R,Yang J,Zhu Y,Zhang Z,Xu X,Wang J,Liu X,Li Z,Li Z,Gong D,Li J,Bi J,Kong C
Mon Oct 01 00:00:00 EDT 2018
Quantitative Global Proteome and Lysine Succinylome Analyses Reveal the Effects of Energy Metabolism in Renal Cell Carcinoma.
Proteomics
Zhang N,Gao R,Yang J,Zhu Y,Zhang Z,Xu X,Wang J,Liu X,Li Z,Li Z,Gong D,Li J,Bi J,Kong C
Mon Oct 01 00:00:00 EDT 2018
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Journal of proteome research
Hu HF,Xu WW,Wang Y,Zheng CC,Zhang WX,Li B,He QY
Fri Jan 05 00:00:00 EST 2018
Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.
Journal of proteome research
Hu HF,Xu WW,Wang Y,Zheng CC,Zhang WX,Li B,He QY
Fri Jan 05 00:00:00 EST 2018
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
International journal of molecular medicine
Zhao Q,Liu Z,Huang B,Yuan Y,Liu X,Zhang H,Qiu F,Zhang Y,Li Y,Miao H,Dong H,Zhang Z
Fri Jun 01 00:00:00 EDT 2018
PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.
International journal of molecular medicine
Zhao Q,Liu Z,Huang B,Yuan Y,Liu X,Zhang H,Qiu F,Zhang Y,Li Y,Miao H,Dong H,Zhang Z
Fri Jun 01 00:00:00 EDT 2018
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Journal of ethnopharmacology
Wu L,Cao KX,Ni ZH,Li WD,Chen ZP,Cheng HB,Liu X
Fri Aug 10 00:00:00 EDT 2018
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Journal of ethnopharmacology
Wu L,Cao KX,Ni ZH,Li WD,Chen ZP,Cheng HB,Liu X
Fri Aug 10 00:00:00 EDT 2018
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Stem cells international
Zhang S,Li J,Jiang H,Gao Y,Cheng P,Cao T,Li D,Wang J,Song Y,Liu B,Wu H,Wang C,Yang L,Pei G
Thu Oct 01 00:00:00 EDT 2020
Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System.
Stem cells international
Zhang S,Li J,Jiang H,Gao Y,Cheng P,Cao T,Li D,Wang J,Song Y,Liu B,Wu H,Wang C,Yang L,Pei G
Thu Oct 01 00:00:00 EDT 2020
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Molecular and cellular biology
Xie K,Zhu M,Xiang P,Chen X,Kasimumali A,Lu R,Wang Q,Mou S,Ni Z,Gu L,Pang H
Mon Jan 01 00:00:00 EST 2018
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.
Molecular and cellular biology
Xie K,Zhu M,Xiang P,Chen X,Kasimumali A,Lu R,Wang Q,Mou S,Ni Z,Gu L,Pang H
Mon Jan 01 00:00:00 EST 2018
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Journal of vascular surgery
Tian Y,Zhang W,Sun J,Zhai H,Yu Y,Qi X,Jones JA,Zhong H
Mon Jan 01 00:00:00 EST 2018
A reproducible swine model of proximal descending thoracic aortic aneurysm created with intra-adventitial application of elastase.
Journal of vascular surgery
Tian Y,Zhang W,Sun J,Zhai H,Yu Y,Qi X,Jones JA,Zhong H
Mon Jan 01 00:00:00 EST 2018
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Metallomics : integrated biometal science
Song GL,Chen C,Wu QY,Zhang ZH,Zheng R,Chen Y,Jia SZ,Ni JZ
Wed Aug 15 00:00:00 EDT 2018
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Metallomics : integrated biometal science
Song GL,Chen C,Wu QY,Zhang ZH,Zheng R,Chen Y,Jia SZ,Ni JZ
Wed Aug 15 00:00:00 EDT 2018
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Fish & shellfish immunology
Huang R,Zhou Q,Shi Y,Zhang J,He J,Xie J
Wed Aug 01 00:00:00 EDT 2018
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Fish & shellfish immunology
Huang R,Zhou Q,Shi Y,Zhang J,He J,Xie J
Wed Aug 01 00:00:00 EDT 2018
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Experimental dermatology
Chen XF,Zhang LJ,Zhang J,Dou X,Shao Y,Jia XJ,Zhang W,Yu B
Sun Apr 01 00:00:00 EDT 2018
MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2.
Experimental dermatology
Chen XF,Zhang LJ,Zhang J,Dou X,Shao Y,Jia XJ,Zhang W,Yu B
Sun Apr 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
AMPH-1 is critical for breast cancer progression.
Journal of Cancer
Chen Y,Liu J,Li L,Xia H,Lin Z,Zhong T
Tue Sep 26 00:00:00 EDT 2023
AMPH-1 is critical for breast cancer progression.
Journal of Cancer
Chen Y,Liu J,Li L,Xia H,Lin Z,Zhong T
Tue Sep 26 00:00:00 EDT 2023
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Journal of Cancer
Li S,Zhao Y,Chen W,Yin L,Zhu J,Zhang H,Cai C,Li P,Huang L,Ma P
Wed Sep 30 00:00:00 EDT 2020
Exosomal ephrinA2 derived from serum as a potential biomarker for prostate cancer.
Journal of Cancer
Li S,Zhao Y,Chen W,Yin L,Zhu J,Zhang H,Cai C,Li P,Huang L,Ma P
Wed Sep 30 00:00:00 EDT 2020
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Toxicology and applied pharmacology
Yan X,Xun M,Wu L,Du X,Zhang F,Zheng J
Fri Jun 15 00:00:00 EDT 2018
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Toxicology and applied pharmacology
Yan X,Xun M,Wu L,Du X,Zhang F,Zheng J
Fri Jun 15 00:00:00 EDT 2018
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
Psychopharmacology
Yang M,Dang R,Xu P,Guo Y,Han W,Liao D,Jiang P
Sat Sep 01 00:00:00 EDT 2018
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.
Psychopharmacology
Yang M,Dang R,Xu P,Guo Y,Han W,Liao D,Jiang P
Sat Sep 01 00:00:00 EDT 2018
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
OncoTargets and therapy
Guo J,Liu Q,Li Z,Guo H,Bai C,Wang F
Wed Oct 04 00:00:00 EDT 2023
miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3.
OncoTargets and therapy
Guo J,Liu Q,Li Z,Guo H,Bai C,Wang F
Wed Oct 04 00:00:00 EDT 2023
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Archives of biochemistry and biophysics
Noori AR,Hosseini ES,Nikkhah M,Hosseinkhani S
Thu Mar 15 00:00:00 EDT 2018
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems.
Archives of biochemistry and biophysics
Noori AR,Hosseini ES,Nikkhah M,Hosseinkhani S
Thu Mar 15 00:00:00 EDT 2018
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Archives of biochemistry and biophysics
Zhang M,Wu J,Zhong W,Zhao Z,Liu Z
Sat Dec 15 00:00:00 EST 2018
Long non-coding RNA BRE-AS1 represses non-small cell lung cancer cell growth and survival via up-regulating NR4A3.
Archives of biochemistry and biophysics
Zhang M,Wu J,Zhong W,Zhao Z,Liu Z
Sat Dec 15 00:00:00 EST 2018
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Biochimica et biophysica acta. Biomembranes
Ge Y,Gu Y,Wang J,Zhang Z
Sun Jul 01 00:00:00 EDT 2018
Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).
Biochimica et biophysica acta. Biomembranes
Ge Y,Gu Y,Wang J,Zhang Z
Sun Jul 01 00:00:00 EDT 2018
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Journal of periodontal research
Ge Y,Li J,Hao Y,Hu Y,Chen D,Wu B,Fang F
Mon Oct 01 00:00:00 EDT 2018
MicroRNA-543 functions as an osteogenesis promoter in human periodontal ligament-derived stem cells by inhibiting transducer of ERBB2, 2.
Journal of periodontal research
Ge Y,Li J,Hao Y,Hu Y,Chen D,Wu B,Fang F
Mon Oct 01 00:00:00 EDT 2018
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
Reproduction (Cambridge, England)
Li H,Yao J,Chang X,Wu J,Duan T,Wang K
Thu Mar 01 00:00:00 EST 2018
LIFR increases the release of soluble endoglin via the upregulation of MMP14 expression in preeclampsia.
Reproduction (Cambridge, England)
Li H,Yao J,Chang X,Wu J,Duan T,Wang K
Thu Mar 01 00:00:00 EST 2018
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Gene
Jiang X,Jiang X,Yang Z
Mon Aug 20 00:00:00 EDT 2018
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer.
Gene
Jiang X,Jiang X,Yang Z
Mon Aug 20 00:00:00 EDT 2018
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Pharmaceutical biology
Wang Y,Guan M,Zhao X,Li X
Sat Dec 01 00:00:00 EST 2018
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
Pharmaceutical biology
Wang Y,Guan M,Zhao X,Li X
Sat Dec 01 00:00:00 EST 2018
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Cell stress & chaperones
Montibeller L,de Belleroche J
Sat Sep 01 00:00:00 EDT 2018
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Cell stress & chaperones
Montibeller L,de Belleroche J
Sat Sep 01 00:00:00 EDT 2018
Generation and propagation of yeast prion [URE3] are elevated under electromagnetic field.
Cell stress & chaperones
Lian HY,Lin KW,Yang C,Cai P
Sun Jul 01 00:00:00 EDT 2018
Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Brain research bulletin
Wang W,Wen D,Duan W,Yin J,Cui C,Wang Y,Li Z,Liu Y,Li C
Tue May 01 00:00:00 EDT 2018
Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.
Brain research bulletin
Wang W,Wen D,Duan W,Yin J,Cui C,Wang Y,Li Z,Liu Y,Li C
Tue May 01 00:00:00 EDT 2018
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Neuroscience
Ma K,Li R,Zhao H,Qu J,Mu N,Liu X,Wang S,Yang C,Feng H,Tan L,Li F
Sat Sep 15 00:00:00 EDT 2018
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats.
Neuroscience
Ma K,Li R,Zhao H,Qu J,Mu N,Liu X,Wang S,Yang C,Feng H,Tan L,Li F
Sat Sep 15 00:00:00 EDT 2018
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Neuroscience
Dai TT,Wang B,Xiao ZY,You Y,Tian SW
Mon Oct 15 00:00:00 EDT 2018
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Neuroscience
Dai TT,Wang B,Xiao ZY,You Y,Tian SW
Mon Oct 15 00:00:00 EDT 2018
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Toxicology in vitro : an international journal published in association with BIBRA
Sun DZ,Song CQ,Xu YM,Wang R,Liu W,Liu Z,Dong XS
Sat Dec 01 00:00:00 EST 2018
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Toxicology in vitro : an international journal published in association with BIBRA
Sun DZ,Song CQ,Xu YM,Wang R,Liu W,Liu Z,Dong XS
Sat Dec 01 00:00:00 EST 2018
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Wang R,Sun DZ,Song CQ,Xu YM,Liu W,Liu Z,Dong XS
Thu Feb 01 00:00:00 EST 2018
Eukaryotic translation initiation factor 2 subunit α (eIF2α) inhibitor salubrinal attenuates paraquat-induced human lung epithelial-like A549 cell apoptosis by regulating the PERK-eIF2α signaling pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Wang R,Sun DZ,Song CQ,Xu YM,Liu W,Liu Z,Dong XS
Thu Feb 01 00:00:00 EST 2018
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
Metabolic brain disease
Ge XH,Shao L,Zhu GJ
Sat Dec 01 00:00:00 EST 2018
Oxymatrine attenuates brain hypoxic-ischemic injury from apoptosis and oxidative stress: role of p-Akt/GSK3β/HO-1/Nrf-2 signaling pathway.
Metabolic brain disease
Ge XH,Shao L,Zhu GJ
Sat Dec 01 00:00:00 EST 2018
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Journal of applied toxicology : JAT
Zeng N,Jiang H,Fan Q,Wang T,Rong W,Li G,Li R,Xu D,Guo T,Wang F,Zeng L,Huang M,Zheng J,Lu F,Chen W,Hu Q,Huang Z,Wang Q
Thu Feb 01 00:00:00 EST 2018
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Journal of applied toxicology : JAT
Zeng N,Jiang H,Fan Q,Wang T,Rong W,Li G,Li R,Xu D,Guo T,Wang F,Zeng L,Huang M,Zheng J,Lu F,Chen W,Hu Q,Huang Z,Wang Q
Thu Feb 01 00:00:00 EST 2018
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
DNA and cell biology
Li J,Qian G,Zhong X,Yu T
Thu Mar 01 00:00:00 EST 2018
Insulin Treatment Cannot Promote Lipogenesis in Rat Fetal Lung in Gestational Diabetes Mellitus Because of Failure to Redress the Imbalance Among SREBP-1, SCAP, and INSIG-1.
DNA and cell biology
Li J,Qian G,Zhong X,Yu T
Thu Mar 01 00:00:00 EST 2018
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Bioorganic & medicinal chemistry
Wu G,Wang H,Zhou W,Zeng B,Mo W,Zhu K,Liu R,Zhou J,Chen C,Chen H
Mon Jul 23 00:00:00 EDT 2018
Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors.
Bioorganic & medicinal chemistry
Wu G,Wang H,Zhou W,Zeng B,Mo W,Zhu K,Liu R,Zhou J,Chen C,Chen H
Mon Jul 23 00:00:00 EDT 2018
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Molecular medicine reports
Chang H,Tian L,Chen J,Tang A,Li C,Li Z,Yang Z
Sun Jul 01 00:00:00 EDT 2018
Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy.
Molecular medicine reports
Chang H,Tian L,Chen J,Tang A,Li C,Li Z,Yang Z
Sun Jul 01 00:00:00 EDT 2018
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
Molecular medicine reports
Wang X,Liu Y,Liu W,Zhang Y,Guo F,Zhang L,Cui M,Liu S,Wu R
Thu Mar 01 00:00:00 EST 2018
Ubenimex, an APN inhibitor, could serve as an anti‑tumor drug in RT112 and 5637 cells by operating in an Akt‑associated manner.
Molecular medicine reports
Wang X,Liu Y,Liu W,Zhang Y,Guo F,Zhang L,Cui M,Liu S,Wu R
Thu Mar 01 00:00:00 EST 2018
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Cardiovascular therapeutics
Wang W,Zhang K,Li X,Ma Z,Zhang Y,Yuan M,Suo Y,Liang X,Tse G,Goudis CA,Liu T,Li G
Fri Jun 01 00:00:00 EDT 2018
Doxycycline attenuates chronic intermittent hypoxia-induced atrial fibrosis in rats.
Cardiovascular therapeutics
Wang W,Zhang K,Li X,Ma Z,Zhang Y,Yuan M,Suo Y,Liang X,Tse G,Goudis CA,Liu T,Li G
Fri Jun 01 00:00:00 EDT 2018
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Behavioural brain research
Tang YY,Wang AP,Wei HJ,Li MH,Zou W,Li X,Wang CY,Zhang P,Tang XQ
Mon Apr 16 00:00:00 EDT 2018
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
Behavioural brain research
Tang YY,Wang AP,Wei HJ,Li MH,Zou W,Li X,Wang CY,Zhang P,Tang XQ
Mon Apr 16 00:00:00 EDT 2018
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Dental traumatology : official publication of International Association for Dental Traumatology
Yuan XJ,Wang YY,Shi BQ,Zhao YM
Sun May 27 00:00:00 EDT 2018
Effect of propolis on preserving human periodontal ligament cells and regulating pro-inflammatory cytokines.
Dental traumatology : official publication of International Association for Dental Traumatology
Yuan XJ,Wang YY,Shi BQ,Zhao YM
Sun May 27 00:00:00 EDT 2018
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Biochemical and biophysical research communications
Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H
Fri Apr 06 00:00:00 EDT 2018
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Biochemical and biophysical research communications
Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H
Fri Apr 06 00:00:00 EDT 2018
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Biochemical and biophysical research communications
Cheng L,Zhao Y,Qi D,Li W,Wang D
Mon Jan 08 00:00:00 EST 2018
Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Biochemical and biophysical research communications
Cheng L,Zhao Y,Qi D,Li W,Wang D
Mon Jan 08 00:00:00 EST 2018
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Biochemical and biophysical research communications
Guan X,Chen S,Liu Y,Wang LL,Zhao Y,Zong ZH
Mon Feb 26 00:00:00 EST 2018
PUM1 promotes ovarian cancer proliferation, migration and invasion.
Biochemical and biophysical research communications
Guan X,Chen S,Liu Y,Wang LL,Zhao Y,Zong ZH
Mon Feb 26 00:00:00 EST 2018
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Biochemical and biophysical research communications
Zhao Y,Liu Y,Jing Z,Peng L,Jin P,Lin Y,Zhou Y,Yang L,Ren J,Xie Q,Jin X
Mon Feb 05 00:00:00 EST 2018
N-oleoylethanolamide suppresses intimal hyperplasia after balloon injury in rats through AMPK/PPARα pathway.
Biochemical and biophysical research communications
Zhao Y,Liu Y,Jing Z,Peng L,Jin P,Lin Y,Zhou Y,Yang L,Ren J,Xie Q,Jin X
Mon Feb 05 00:00:00 EST 2018
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Biochemical and biophysical research communications
Xu Q,Cui Y,Luan J,Zhou X,Li H,Han J
Sun Mar 25 00:00:00 EDT 2018
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Biochemical and biophysical research communications
Xu Q,Cui Y,Luan J,Zhou X,Li H,Han J
Sun Mar 25 00:00:00 EDT 2018
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
BioMed research international
Xu J,Wang J,Cheng Y,Li X,He M,Zhu J,Han H,Wei G,Kong H,Xie W,Wang H,Zuo X
Wed Sep 05 00:00:00 EDT 2018
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
BioMed research international
Xu J,Wang J,Cheng Y,Li X,He M,Zhu J,Han H,Wei G,Kong H,Xie W,Wang H,Zuo X
Wed Sep 05 00:00:00 EDT 2018
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Veterinary microbiology
Guo F,Yu X,Xu A,Xu J,Wang Q,Guo Y,Wu X,Tang Y,Ding Z,Zhang Y,Gong T,Pan Z,Li S,Kong L
Sun Jul 01 00:00:00 EDT 2018
Japanese encephalitis virus induces apoptosis by inhibiting Foxo signaling pathway.
Veterinary microbiology
Guo F,Yu X,Xu A,Xu J,Wang Q,Guo Y,Wu X,Tang Y,Ding Z,Zhang Y,Gong T,Pan Z,Li S,Kong L
Sun Jul 01 00:00:00 EDT 2018
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Fitoterapia
Zheng YD,Bai G,Tang C,Ke CQ,Yao S,Tong LJ,Feng F,Li Y,Ding J,Xie H,Ye Y
Thu Mar 01 00:00:00 EST 2018
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities.
Fitoterapia
Zheng YD,Bai G,Tang C,Ke CQ,Yao S,Tong LJ,Feng F,Li Y,Ding J,Xie H,Ye Y
Thu Mar 01 00:00:00 EST 2018
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Neuroscience letters
Wang Y,Zhang R,Xing X,Guo J,Xie F,Zhang G,Qin X
Mon Jan 01 00:00:00 EST 2018
Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.
Neuroscience letters
Wang Y,Zhang R,Xing X,Guo J,Xie F,Zhang G,Qin X
Mon Jan 01 00:00:00 EST 2018
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Clinical and experimental pharmacology & physiology
Cheng Q,Liu L,Fu Y,Zhang Y,Yang Y,Liu J
Thu Feb 01 00:00:00 EST 2018
RhPDCD5 combined with dexamethasone increases antitumor activity in multiple myeloma partially via inhibiting the Wnt signalling pathway.
Clinical and experimental pharmacology & physiology
Cheng Q,Liu L,Fu Y,Zhang Y,Yang Y,Liu J
Thu Feb 01 00:00:00 EST 2018
Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Endocrine journal
Sun D,Zhou L,Wang S,Liu T,Zhu J,Jia Y,Xu J,Chen H,Wang Q,Xu F,Zhang Y,Ye L
Wed Mar 28 00:00:00 EDT 2018
Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Endocrine journal
Sun D,Zhou L,Wang S,Liu T,Zhu J,Jia Y,Xu J,Chen H,Wang Q,Xu F,Zhang Y,Ye L
Wed Mar 28 00:00:00 EDT 2018
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
Respiratory physiology & neurobiology
He M,Ma S,Cai Q,Wu Y,Shao C,Kong H,Wang H,Zeng X,Xie W
Mon Jan 01 00:00:00 EST 2018
Hypoxia induces the dysfunction of human endothelial colony-forming cells via HIF-1α signaling.
Respiratory physiology & neurobiology
He M,Ma S,Cai Q,Wu Y,Shao C,Kong H,Wang H,Zeng X,Xie W
Mon Jan 01 00:00:00 EST 2018
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
Experimental and therapeutic medicine
Shi G,Zhao JW,Sun XX,Ma JF,Wang P,He FC,Ming L
Sun Apr 01 00:00:00 EDT 2018
TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma.
Experimental and therapeutic medicine
Shi G,Zhao JW,Sun XX,Ma JF,Wang P,He FC,Ming L
Sun Apr 01 00:00:00 EDT 2018
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
Experimental and therapeutic medicine
Liu M,Zhang J,Liu C
Mon Jan 01 00:00:00 EST 2018
Clinical efficacy of recombinant human latrophilin 3 antibody in the treatment of pediatric asthma.
Experimental and therapeutic medicine
Liu M,Zhang J,Liu C
Mon Jan 01 00:00:00 EST 2018
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
Experimental and therapeutic medicine
Xie W,Lu J,Lu Q,Wang X,Long H,Huang J,Guo Z
Wed Aug 01 00:00:00 EDT 2018
Matrine inhibits the proliferation and migration of lung cancer cells through regulation of the protein kinase B/glycogen synthase kinase-3β signaling pathways.
Experimental and therapeutic medicine
Xie W,Lu J,Lu Q,Wang X,Long H,Huang J,Guo Z
Wed Aug 01 00:00:00 EDT 2018
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Archives of virology
Wang H,Xin X,Wang M,Han L,Li J,Hao Y,Zheng C,Shen C
Fri Jun 01 00:00:00 EDT 2018
Myxovirus resistance protein A inhibits hepatitis C virus replication through JAK-STAT pathway activation.
Archives of virology
Wang H,Xin X,Wang M,Han L,Li J,Hao Y,Zheng C,Shen C
Fri Jun 01 00:00:00 EDT 2018
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Cheng ZJ,Dai TM,Shen YY,He JL,Li J,Tu JL
Thu Nov 01 00:00:00 EDT 2018
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Cheng ZJ,Dai TM,Shen YY,He JL,Li J,Tu JL
Thu Nov 01 00:00:00 EDT 2018
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
The Tohoku journal of experimental medicine
Zhang X,Guo J,Wang H,Zhang C,Shi N,Cai W,Jin T,Lin Z,Ma Y,Yang X,Xia Q,Xue P
Sun Jul 01 00:00:00 EDT 2018
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
The Tohoku journal of experimental medicine
Zhang X,Guo J,Wang H,Zhang C,Shi N,Cai W,Jin T,Lin Z,Ma Y,Yang X,Xia Q,Xue P
Sun Jul 01 00:00:00 EDT 2018
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Yang Z,Jia H,Bai Y,Wang W
Mon Oct 01 00:00:00 EDT 2018
Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Yang Z,Jia H,Bai Y,Wang W
Mon Oct 01 00:00:00 EDT 2018
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Stem cell research
Xu A,Zhou R,Tu J,Huo Z,Zhu D,Wang D,Gingold JA,Mata H,Rao PH,Liu M,Mohamed AMT,Kong CSL,Jewell BE,Xia W,Zhao R,Hung MC,Lee DF
Tue May 01 00:00:00 EDT 2018
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Stem cell research
Xu A,Zhou R,Tu J,Huo Z,Zhu D,Wang D,Gingold JA,Mata H,Rao PH,Liu M,Mohamed AMT,Kong CSL,Jewell BE,Xia W,Zhao R,Hung MC,Lee DF
Tue May 01 00:00:00 EDT 2018
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Frontiers in immunology
Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H
Fri Oct 25 00:00:00 EDT 2019
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Frontiers in immunology
Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H
Fri Oct 25 00:00:00 EDT 2019
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Scientific reports
Liao Y,Wang W,Huang X,Sun Y,Tian S,Cai P
Fri Oct 12 00:00:00 EDT 2018
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Scientific reports
Liao Y,Wang W,Huang X,Sun Y,Tian S,Cai P
Fri Oct 12 00:00:00 EDT 2018
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Cancer communications (London, England)
Tong M,Deng Z,Yang M,Xu C,Zhang X,Zhang Q,Liao Y,Deng X,Lv D,Zhang X,Zhang Y,Li P,Song L,Wang B,Al-Dherasi A,Li Z,Liu Q
Wed Sep 19 00:00:00 EDT 2018
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells.
Cancer communications (London, England)
Tong M,Deng Z,Yang M,Xu C,Zhang X,Zhang Q,Liao Y,Deng X,Lv D,Zhang X,Zhang Y,Li P,Song L,Wang B,Al-Dherasi A,Li Z,Liu Q
Wed Sep 19 00:00:00 EDT 2018
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
PloS one
Spencer NY,Yang Z,Sullivan JC,Klein T,Stanton RC
Tue Jan 08 00:00:00 EST 2019
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.
PloS one
Spencer NY,Yang Z,Sullivan JC,Klein T,Stanton RC
Tue Jan 08 00:00:00 EST 2019
Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.
Journal of agricultural and food chemistry
Bi D,Lai Q,Cai N,Li T,Zhang Y,Han Q,Peng Y,Xu H,Lu J,Bao W,Liu Q,Xu X
Wed Mar 07 00:00:00 EST 2018
Protective Effect of Extract of Bletilla Striata on Isoflurane Induced Neuronal Injury By Altering PI3K/Akt Pathway.
Translational neuroscience
Zhao G,Li K,Chen J,Li L
Thu Mar 31 00:00:00 EDT 2022
Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.
RSC advances
Zhang S,Liu H,Li H,Wu M,Yu Y,Li F,Cheng X
Wed Apr 11 00:00:00 EDT 2018
Geniposide attenuates Aβ25-35-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
RSC advances
Huang XF,Li JJ,Tao YG,Wang XQ,Zhang RL,Zhang JL,Su ZQ,Huang QH,Deng YH
Tue May 22 00:00:00 EDT 2018
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Nature communications
Sheng C,Yao C,Wang Z,Chen H,Zhao Y,Xu D,Huang H,Huang W,Chen S
Mon Oct 22 00:00:00 EDT 2018
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing.
Nature communications
Sheng C,Yao C,Wang Z,Chen H,Zhao Y,Xu D,Huang H,Huang W,Chen S
Mon Oct 22 00:00:00 EDT 2018
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Stem cell reports
Li S,Pan H,Tan C,Sun Y,Song Y,Zhang X,Yang W,Wang X,Li D,Dai Y,Ma Q,Xu C,Zhu X,Kang L,Fu Y,Xu X,Shu J,Zhou N,Han F,Qin D,Huang W,Liu Z,Yan Q
Tue Mar 13 00:00:00 EDT 2018
Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.
Stem cell reports
Li S,Pan H,Tan C,Sun Y,Song Y,Zhang X,Yang W,Wang X,Li D,Dai Y,Ma Q,Xu C,Zhu X,Kang L,Fu Y,Xu X,Shu J,Zhou N,Han F,Qin D,Huang W,Liu Z,Yan Q
Tue Mar 13 00:00:00 EDT 2018
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
Drug design, development and therapy
Liu M,Chen X,Liu H,Di Y
Mon Oct 29 00:00:00 EDT 2018
Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice.
Drug design, development and therapy
Liu M,Chen X,Liu H,Di Y
Mon Oct 29 00:00:00 EDT 2018
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Journal of experimental & clinical cancer research : CR
Fan Q,Yang L,Zhang X,Ma Y,Li Y,Dong L,Zong Z,Hua X,Su D,Li H,Liu J
Fri Jan 19 00:00:00 EST 2018
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells.
Journal of experimental & clinical cancer research : CR
Fan Q,Yang L,Zhang X,Ma Y,Li Y,Dong L,Zong Z,Hua X,Su D,Li H,Liu J
Fri Jan 19 00:00:00 EST 2018
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Reproductive biology and endocrinology : RB&E
Li C,Zhang HY,Liang Y,Xia W,Zhu Q,Zhang D,Huang Z,Liang GL,Xue RH,Qi H,He XQ,Yuan JJ,Tan YJ,Huang HF,Zhang J
Wed Jun 20 00:00:00 EDT 2018
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Reproductive biology and endocrinology : RB&E
Li C,Zhang HY,Liang Y,Xia W,Zhu Q,Zhang D,Huang Z,Liang GL,Xue RH,Qi H,He XQ,Yuan JJ,Tan YJ,Huang HF,Zhang J
Wed Jun 20 00:00:00 EDT 2018
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Journal of experimental & clinical cancer research : CR
Peng Y,Wang Y,Tang N,Sun D,Lan Y,Yu Z,Zhao X,Feng L,Zhang B,Jin L,Yu F,Ma X,Lv C
Fri Oct 12 00:00:00 EDT 2018
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Journal of experimental & clinical cancer research : CR
Peng Y,Wang Y,Tang N,Sun D,Lan Y,Yu Z,Zhao X,Feng L,Zhang B,Jin L,Yu F,Ma X,Lv C
Fri Oct 12 00:00:00 EDT 2018
Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Chen S,Huang Y,Wan S,Huang Y,Liang H,Chen S
Fri Jun 01 00:00:00 EDT 2018
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Molecular medicine reports
Liang D,Wang KJ,Tang ZQ,Liu RH,Zeng F,Cheng MY,Lian QS,Wu HK
Fri Jun 01 00:00:00 EDT 2018
Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.
Biotechnology and applied biochemistry
Sun D,Liu Y,Wu H,Ren Y,Ma X,Wu H,Sun G
Thu Mar 01 00:00:00 EST 2018
Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.
RSC advances
Tian H,Sun W,Zhang Q,Li X,Sang Y,Li J,Niu Y,Ding H
Wed Jun 27 00:00:00 EDT 2018
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Medical science monitor : international medical journal of experimental and clinical research
Zhang Y,Yang B,Zhao J,Li X,Zhang L,Zhai Z
Mon Jan 15 00:00:00 EST 2018
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Medical science monitor : international medical journal of experimental and clinical research
Zhang Y,Yang B,Zhao J,Li X,Zhang L,Zhai Z
Mon Jan 15 00:00:00 EST 2018
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Molecular genetics and genomics : MGG
Wang F,Guo T,Jiang H,Li R,Wang T,Zeng N,Dong G,Zeng X,Li D,Xiao Y,Hu Q,Chen W,Xing X,Wang Q
Fri Jun 01 00:00:00 EDT 2018
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Molecular genetics and genomics : MGG
Wang F,Guo T,Jiang H,Li R,Wang T,Zeng N,Dong G,Zeng X,Li D,Xiao Y,Hu Q,Chen W,Xing X,Wang Q
Fri Jun 01 00:00:00 EDT 2018
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Drug design, development and therapy
Feng Y,Chen L,Luo Q,Wu M,Chen Y,Shi X
Wed Aug 29 00:00:00 EDT 2018
Involvement of microRNA-146a in diabetic peripheral neuropathy through the regulation of inflammation.
Drug design, development and therapy
Feng Y,Chen L,Luo Q,Wu M,Chen Y,Shi X
Wed Aug 29 00:00:00 EDT 2018
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Molecular vision
Zhang Y,Zhao L,Wang L,Yang X,Zhou A,Wang J
Mon Nov 12 00:00:00 EST 2018
Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.
Molecular vision
Zhang Y,Zhao L,Wang L,Yang X,Zhou A,Wang J
Mon Nov 12 00:00:00 EST 2018
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Molecules (Basel, Switzerland)
Yu Y,Li X,Mi J,Qu L,Yang D,Guo J,Qiu L
Wed Sep 12 00:00:00 EDT 2018
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Molecules (Basel, Switzerland)
Yu Y,Li X,Mi J,Qu L,Yang D,Guo J,Qiu L
Wed Sep 12 00:00:00 EDT 2018
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Nutrients
Kanwal S,Joseph TP,Owusu L,Xiaomeng R,Meiqi L,Yi X
Tue Jul 31 00:00:00 EDT 2018
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Nutrients
Kanwal S,Joseph TP,Owusu L,Xiaomeng R,Meiqi L,Yi X
Tue Jul 31 00:00:00 EDT 2018
Inhibitor of Bruton's tyrosine kinases, PCI-32765, decreases pro-inflammatory mediators' production in high glucose-induced macrophages.
International immunopharmacology
Fan Z,Wang Y,Xu X,Wu Y
Tue May 01 00:00:00 EDT 2018
TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.
Cancer letters
Wei WS,Chen X,Guo LY,Li XD,Deng MH,Yuan GJ,He LY,Li YH,Zhang ZL,Jiang LJ,Chen RX,Ma XD,Wei S,Ma NF,Liu ZW,Luo JH,Zhou FJ,Xie D
Sun Oct 28 00:00:00 EDT 2018
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
Oncology research
Zeng R,Tan G,Li W,Ma Y
Fri Jan 19 00:00:00 EST 2018
Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos.
Cell cycle (Georgetown, Tex.)
Long Y,Wang G,Li K,Zhang Z,Zhang P,Zhang J,Zhang X,Bao Y,Yang X,Wang P
Tue Nov 05 00:00:00 EST 2019
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
DNA repair
Sengupta S,Yang C,Hegde ML,Hegde PM,Mitra J,Pandey A,Dutta A,Datarwala AT,Bhakat KK,Mitra S
Tue Oct 02 00:00:00 EDT 2018
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Medical science monitor basic research
Li S,Li T,Li X,Yao Y,Jiang X,Zhao L,Guo W
Mon Nov 05 00:00:00 EST 2018
MicroRNA-32 Regulates Development and Progression of Hepatocellular Carcinoma by Targeting ADAMTS9 and Affects Its Prognosis.
Medical science monitor basic research
Li S,Li T,Li X,Yao Y,Jiang X,Zhao L,Guo W
Mon Nov 05 00:00:00 EST 2018
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
International journal of molecular sciences
Bian Y,Guo J,Qiao L,Sun X
Sat Jan 13 00:00:00 EST 2018
miR-3189-3p Mimics Enhance the Effects of S100A4 siRNA on the Inhibition of Proliferation and Migration of Gastric Cancer Cells by Targeting CFL2.
International journal of molecular sciences
Bian Y,Guo J,Qiao L,Sun X
Sat Jan 13 00:00:00 EST 2018
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model.
The journal of headache and pain
Wang XY,Zhou HR,Wang S,Liu CY,Qin GC,Fu QQ,Zhou JY,Chen LX
Tue Nov 06 00:00:00 EST 2018
Pathological Features of Staphylococcus aureus Induced Mastitis in Dairy Cows and Isobaric-Tags-for-Relative-and-Absolute-Quantitation Proteomic Analyses.
Journal of agricultural and food chemistry
Chen Z,Xia H,Shen H,Xu X,Arbab AAI,Li M,Zhang H,Mao Y,Yang Z
Wed Apr 18 00:00:00 EDT 2018
Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.
Virology
Ren C,Yu M,Zhang Y,Fan M,Chang F,Xing L,Liu Y,Wang Y,Qi X,Liu C,Zhang Y,Cui H,Li K,Gao L,Pan Q,Wang X,Gao Y
Fri Jun 01 00:00:00 EDT 2018
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.
British journal of pharmacology
Luo J,Xu Q,Jiang B,Zhang R,Jia X,Li X,Wang L,Guo C,Wu N,Shi D
Mon Jan 01 00:00:00 EST 2018
Mussel adhesive protein fused with VE-cadherin domain specifically triggers endothelial cell adhesion.
Journal of materials chemistry. B
Yang D,Qiu J,Xu N,Zhao Y,Li T,Ma Q,Huang J,Wang G
Thu Jun 28 00:00:00 EDT 2018
Promotion of autophagosome-lysosome fusion via salvianolic acid A-mediated SIRT1 up-regulation ameliorates alcoholic liver disease.
RSC advances
Shi X,Sun R,Zhao Y,Fu R,Wang R,Zhao H,Wang Z,Tang F,Zhang N,Tian X,Yao J
Wed May 30 00:00:00 EDT 2018
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Frontiers in pharmacology
Peng JH,Leng J,Tian HJ,Yang T,Fang Y,Feng Q,Zhao Y,Hu YY
Thu Oct 01 00:00:00 EDT 2020
Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet.
Frontiers in pharmacology
Peng JH,Leng J,Tian HJ,Yang T,Fang Y,Feng Q,Zhao Y,Hu YY
Thu Oct 01 00:00:00 EDT 2020
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Frontiers in pharmacology
Feng Y,Chu A,Luo Q,Wu M,Shi X,Chen Y
Thu Oct 01 00:00:00 EDT 2020
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Frontiers in pharmacology
Feng Y,Chu A,Luo Q,Wu M,Shi X,Chen Y
Thu Oct 01 00:00:00 EDT 2020
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Nature microbiology
Zhang H,Li Y,Wang HB,Zhang A,Chen ML,Fang ZX,Dong XD,Li SB,Du Y,Xiong D,He JY,Li MZ,Liu YM,Zhou AJ,Zhong Q,Zeng YX,Kieff E,Zhang Z,Gewurz BE,Zhao B,Zeng MS
Thu Feb 01 00:00:00 EST 2018
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Nature microbiology
Zhang H,Li Y,Wang HB,Zhang A,Chen ML,Fang ZX,Dong XD,Li SB,Du Y,Xiong D,He JY,Li MZ,Liu YM,Zhou AJ,Zhong Q,Zeng YX,Kieff E,Zhang Z,Gewurz BE,Zhao B,Zeng MS
Thu Feb 01 00:00:00 EST 2018
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
Cell death & disease
Yang Y,Sun K,Liu W,Zhang L,Peng K,Zhang S,Li S,Yang M,Jiang Z,Lu F,Zhu X
Wed Sep 05 00:00:00 EDT 2018
Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells.
Cell death & disease
Yang Y,Sun K,Liu W,Zhang L,Peng K,Zhang S,Li S,Yang M,Jiang Z,Lu F,Zhu X
Wed Sep 05 00:00:00 EDT 2018
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer.
World journal of gastroenterology
Xu WY,Hu QS,Qin Y,Zhang B,Liu WS,Ni QX,Xu J,Yu XJ
Wed Nov 21 00:00:00 EST 2018
Renal protective effect of Paeoniflorin by inhibition of JAK2/STAT3 signaling pathway in diabetic mice.
Bioscience trends
Li X,Wang Y,Wang K,Wu Y
Sun May 13 00:00:00 EDT 2018
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Redox biology
Jia Y,Wang F,Guo Q,Li M,Wang L,Zhang Z,Jiang S,Jin H,Chen A,Tan S,Zhang F,Shao J,Zheng S
Mon Oct 01 00:00:00 EDT 2018
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Redox biology
Jia Y,Wang F,Guo Q,Li M,Wang L,Zhang Z,Jiang S,Jin H,Chen A,Tan S,Zhang F,Shao J,Zheng S
Mon Oct 01 00:00:00 EDT 2018
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
Cell death & disease
Yao ZQ,Zhang X,Zhen Y,He XY,Zhao S,Li XF,Yang B,Gao F,Guo FY,Fu L,Liu XZ,Duan CZ
Tue Jul 10 00:00:00 EDT 2018
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma.
Cell death & disease
Yao ZQ,Zhang X,Zhen Y,He XY,Zhao S,Li XF,Yang B,Gao F,Guo FY,Fu L,Liu XZ,Duan CZ
Tue Jul 10 00:00:00 EDT 2018
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Reproductive biology and endocrinology : RB&E
Wang X,Zhang X,Hu L,Li H
Thu May 31 00:00:00 EDT 2018
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Reproductive biology and endocrinology : RB&E
Wang X,Zhang X,Hu L,Li H
Thu May 31 00:00:00 EDT 2018
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Cell death & disease
Li M,Chai HF,Peng F,Meng YT,Zhang LZ,Zhang L,Zou H,Liang QL,Li MM,Mao KG,Sun DX,Tong MY,Deng ZQ,Hou ZJ,Zhao Y,Li J,Wang XC,Lv SS,Zhang QQ,Yu X,Lam EW,Liu Q,Cui XN,Xu J
Fri Nov 02 00:00:00 EDT 2018
Estrogen receptor β upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma.
Cell death & disease
Li M,Chai HF,Peng F,Meng YT,Zhang LZ,Zhang L,Zou H,Liang QL,Li MM,Mao KG,Sun DX,Tong MY,Deng ZQ,Hou ZJ,Zhao Y,Li J,Wang XC,Lv SS,Zhang QQ,Yu X,Lam EW,Liu Q,Cui XN,Xu J
Fri Nov 02 00:00:00 EDT 2018
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Drug design, development and therapy
Liao D,Guo Y,Xiang D,Dang R,Xu P,Cai H,Cao L,Jiang P
Tue Sep 04 00:00:00 EDT 2018
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin.
Drug design, development and therapy
Liao D,Guo Y,Xiang D,Dang R,Xu P,Cai H,Cao L,Jiang P
Tue Sep 04 00:00:00 EDT 2018
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Cell death & disease
Ma X,Ma X,Qiu Y,Zhu L,Lin Y,You Y,Ma D,Qin Z,Sun C,Zhao Y,Sun Y,Han L
Tue May 22 00:00:00 EDT 2018
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
Cell death & disease
Ma X,Ma X,Qiu Y,Zhu L,Lin Y,You Y,Ma D,Qin Z,Sun C,Zhao Y,Sun Y,Han L
Tue May 22 00:00:00 EDT 2018
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Nutrients
Teng Y,Li D,Guruvaiah P,Xu N,Xie Z
Fri Jan 12 00:00:00 EST 2018
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.
Nutrients
Teng Y,Li D,Guruvaiah P,Xu N,Xie Z
Fri Jan 12 00:00:00 EST 2018
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
EBioMedicine
Hu X,Li YQ,Li QG,Ma YL,Peng JJ,Cai SJ
Wed Aug 01 00:00:00 EDT 2018
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
EBioMedicine
Hu X,Li YQ,Li QG,Ma YL,Peng JJ,Cai SJ
Wed Aug 01 00:00:00 EDT 2018
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Xu H,Gong Z,Zhou S,Yang S,Wang D,Chen X,Wu J,Liu L,Zhong S,Zhao J,Tang J
Tue Sep 18 00:00:00 EDT 2018
Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Xu H,Gong Z,Zhou S,Yang S,Wang D,Chen X,Wu J,Liu L,Zhong S,Zhao J,Tang J
Tue Sep 18 00:00:00 EDT 2018
ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.
Journal of immunology (Baltimore, Md. : 1950)
Feng Q,Miao Y,Ge J,Yuan Y,Zuo Y,Qian L,Liu J,Cheng Q,Guo T,Zhang L,Yu Z,Zheng H
Sun Jul 15 00:00:00 EDT 2018
Role of TGF-β activated kinase-1 inhibitor on the interaction between macrophages and mesangial cells on the condition of high glucose.
Immunological investigations
Fan Z,Xu X,Qi X,Wu Y
Sun Apr 01 00:00:00 EDT 2018
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells.
Biochemical and biophysical research communications
Li A,Liu Y,Zhu X,Sun X,Feng X,Li D,Zhang J,Zhu M,Zhao Z
Fri Apr 06 00:00:00 EDT 2018
New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Molecules (Basel, Switzerland)
Zhang L,Liu W,Wang Q,Li Q,Wang H,Wang J,Teng T,Chen M,Ji A,Li Y
Fri Mar 02 00:00:00 EST 2018
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Poultry science
Shao YZ,Zhao HJ,Wang Y,Liu JJ,Li JL,Luo LY,Xing MW
Sat Sep 01 00:00:00 EDT 2018
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Poultry science
Shao YZ,Zhao HJ,Wang Y,Liu JJ,Li JL,Luo LY,Xing MW
Sat Sep 01 00:00:00 EDT 2018
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
International journal of molecular sciences
Cheng Z,Liu L,Wang Z,Cai Y,Xu Q,Chen P
Thu Feb 15 00:00:00 EST 2018
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
International journal of molecular sciences
Cheng Z,Liu L,Wang Z,Cai Y,Xu Q,Chen P
Thu Feb 15 00:00:00 EST 2018
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Oncotarget
Steinbichler TB,Alshaimaa A,Maria MV,Daniel D,Herbert R,Jozsef D,Ira-Ida S
Tue Jan 09 00:00:00 EST 2018
Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells.
Oncotarget
Steinbichler TB,Alshaimaa A,Maria MV,Daniel D,Herbert R,Jozsef D,Ira-Ida S
Tue Jan 09 00:00:00 EST 2018
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Scientific reports
Gao L,Wang KX,Zhou YZ,Fang JS,Qin XM,Du GH
Fri Jan 12 00:00:00 EST 2018
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Scientific reports
Gao L,Wang KX,Zhou YZ,Fang JS,Qin XM,Du GH
Fri Jan 12 00:00:00 EST 2018
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Cell death & disease
Zhu ZD,Yu T,Liu HJ,Jin J,He J
Fri Jan 19 00:00:00 EST 2018
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation.
Cell death & disease
Zhu ZD,Yu T,Liu HJ,Jin J,He J
Fri Jan 19 00:00:00 EST 2018
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
Cells
D'Ignazio L,Batie M,Rocha S
Wed Aug 08 00:00:00 EDT 2018
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway.
Cells
D'Ignazio L,Batie M,Rocha S
Wed Aug 08 00:00:00 EDT 2018
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Scientific reports
Wang Q,He G,Hou M,Chen L,Chen S,Xu A,Fu Y
Tue May 01 00:00:00 EDT 2018
Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Scientific reports
Wang Q,He G,Hou M,Chen L,Chen S,Xu A,Fu Y
Tue May 01 00:00:00 EDT 2018
Distinct autophagy-inducing abilities of similar-sized nanoparticles in cell culture and live C. elegans.
Nanoscale
Wang Q,Zhou Y,Fu R,Zhu Y,Song B,Zhong Y,Wu S,Shi Y,Wu Y,Su Y,Zhang H,He Y
Thu Dec 13 00:00:00 EST 2018
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
European journal of pharmacology
Wang Y,Wu Z,Hu L
Wed Sep 05 00:00:00 EDT 2018
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Cell death & disease
Aulas A,Lyons SM,Fay MM,Anderson P,Ivanov P
Tue Nov 13 00:00:00 EST 2018
Mechanism of prolactin inhibition of miR-135b via methylation in goat mammary epithelial cells.
Journal of cellular physiology
Chen Z,Luo J,Zhang C,Ma Y,Sun S,Zhang T,Loor JJ
Mon Jan 01 00:00:00 EST 2018
Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-β1/Smad pathway in DN rats.
RSC advances
Gao F,He X,Liang S,Liu S,Liu H,He Q,Chen L,Jiang H,Zhang Y
Mon Oct 15 00:00:00 EDT 2018
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Nature communications
Padilla-Rodriguez M,Parker SS,Adams DG,Westerling T,Puleo JI,Watson AW,Hill SM,Noon M,Gaudin R,Aaron J,Tong D,Roe DJ,Knudsen B,Mouneimne G
Mon Jul 30 00:00:00 EDT 2018
The actin cytoskeletal architecture of estrogen receptor positive breast cancer cells suppresses invasion.
Nature communications
Padilla-Rodriguez M,Parker SS,Adams DG,Westerling T,Puleo JI,Watson AW,Hill SM,Noon M,Gaudin R,Aaron J,Tong D,Roe DJ,Knudsen B,Mouneimne G
Mon Jul 30 00:00:00 EDT 2018
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Redox biology
Zhou MX,Li GH,Sun B,Xu YW,Li AL,Li YR,Ren DM,Wang XN,Wen XS,Lou HX,Shen T
Sun Apr 01 00:00:00 EDT 2018
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells.
Redox biology
Zhou MX,Li GH,Sun B,Xu YW,Li AL,Li YR,Ren DM,Wang XN,Wen XS,Lou HX,Shen T
Sun Apr 01 00:00:00 EDT 2018
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
eLife
Fan L,Lu Y,Shen X,Shao H,Suo L,Wu Q
Mon Jun 18 00:00:00 EDT 2018
Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
eLife
Fan L,Lu Y,Shen X,Shao H,Suo L,Wu Q
Mon Jun 18 00:00:00 EDT 2018
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Scientific reports
Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J
Mon Feb 19 00:00:00 EST 2018
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Scientific reports
Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J
Mon Feb 19 00:00:00 EST 2018
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
International journal of molecular sciences
Yan XT,Sun YS,Ren S,Zhao LC,Liu WC,Chen C,Wang Z,Li W
Tue May 01 00:00:00 EDT 2018
Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.
International journal of molecular sciences
Yan XT,Sun YS,Ren S,Zhao LC,Liu WC,Chen C,Wang Z,Li W
Tue May 01 00:00:00 EDT 2018
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Archives of toxicology
Zhao Y,Li Y,Wang J,Manthari RK,Wang J
Thu Nov 01 00:00:00 EDT 2018
Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1.
International journal of oncology
Ren W,Zhang Y,Zhang L,Lin Q,Zhang J,Xu G
Tue May 01 00:00:00 EDT 2018
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.
Pharmaceutical biology
Zhang H,Ren QC,Ren Y,Zhao L,Yang F,Zhang Y,Zhao WJ,Tan YZ,Shen XF
Sat Dec 01 00:00:00 EST 2018
Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.
ACS chemical neuroscience
Chen H,Liu S,Li S,Chen J,Ni J,Liu Q
Wed Jul 18 00:00:00 EDT 2018
ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
The Journal of clinical investigation
Tartey S,Gurung P,Dasari TK,Burton A,Kanneganti TD
Tue May 01 00:00:00 EDT 2018
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Genes & development
Guo X,Zhao Y,Yan H,Yang Y,Shen S,Dai X,Ji X,Ji F,Gong XG,Li L,Bai X,Feng XH,Liang T,Ji J,Chen L,Wang H,Zhao B
Wed Feb 01 00:00:00 EST 2017
Single tumor-initiating cells evade immune clearance by recruiting type II macrophages.
Genes & development
Guo X,Zhao Y,Yan H,Yang Y,Shen S,Dai X,Ji X,Ji F,Gong XG,Li L,Bai X,Feng XH,Liang T,Ji J,Chen L,Wang H,Zhao B
Wed Feb 01 00:00:00 EST 2017
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Andrew RJ,Fernandez CG,Stanley M,Jiang H,Nguyen P,Rice RC,Buggia-Prévot V,De Rossi P,Vetrivel KS,Lamb R,Argemi A,Allaert ES,Rathbun EM,Krause SV,Wagner SL,Parent AT,Holtzman DM,Thinakaran G
Tue Nov 07 00:00:00 EST 2017
Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Andrew RJ,Fernandez CG,Stanley M,Jiang H,Nguyen P,Rice RC,Buggia-Prévot V,De Rossi P,Vetrivel KS,Lamb R,Argemi A,Allaert ES,Rathbun EM,Krause SV,Wagner SL,Parent AT,Holtzman DM,Thinakaran G
Tue Nov 07 00:00:00 EST 2017
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Proceedings of the National Academy of Sciences of the United States of America
Lorenzo DN,Bennett V
Tue Nov 28 00:00:00 EST 2017
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Proceedings of the National Academy of Sciences of the United States of America
Lorenzo DN,Bennett V
Tue Nov 28 00:00:00 EST 2017
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Experimental & molecular medicine
Hu J,Luo H,Wang J,Tang W,Lu J,Wu S,Xiong Z,Yang G,Chen Z,Lan T,Zhou H,Nie J,Jiang Y,Chen P
Fri Aug 25 00:00:00 EDT 2017
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Experimental & molecular medicine
Hu J,Luo H,Wang J,Tang W,Lu J,Wu S,Xiong Z,Yang G,Chen Z,Lan T,Zhou H,Nie J,Jiang Y,Chen P
Fri Aug 25 00:00:00 EDT 2017
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Antiviral research
Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H
Tue Aug 01 00:00:00 EDT 2017
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Antiviral research
Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H
Tue Aug 01 00:00:00 EDT 2017
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
EMBO reports
Jiang D,Wei S,Chen F,Zhang Y,Li J
Mon May 01 00:00:00 EDT 2017
TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response.
EMBO reports
Jiang D,Wei S,Chen F,Zhang Y,Li J
Mon May 01 00:00:00 EDT 2017
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Journal of medicinal chemistry
Ouyang L,Zhang L,Liu J,Fu L,Yao D,Zhao Y,Zhang S,Wang G,He G,Liu B
Thu Dec 28 00:00:00 EST 2017
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.
Journal of medicinal chemistry
Ouyang L,Zhang L,Liu J,Fu L,Yao D,Zhao Y,Zhang S,Wang G,He G,Liu B
Thu Dec 28 00:00:00 EST 2017
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
Molecular oncology
Hsieh FS,Chen YL,Hung MH,Chu PY,Tsai MH,Chen LJ,Hsiao YJ,Shih CT,Chang MJ,Chao TI,Shiau CW,Chen KF
Tue Aug 01 00:00:00 EDT 2017
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.
Molecular oncology
Hsieh FS,Chen YL,Hung MH,Chu PY,Tsai MH,Chen LJ,Hsiao YJ,Shih CT,Chang MJ,Chao TI,Shiau CW,Chen KF
Tue Aug 01 00:00:00 EDT 2017
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
European journal of medicinal chemistry
Wang L,Li L,Zhou ZH,Jiang ZY,You QD,Xu XL
Fri Aug 18 00:00:00 EDT 2017
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
European journal of medicinal chemistry
Wang L,Li L,Zhou ZH,Jiang ZY,You QD,Xu XL
Fri Aug 18 00:00:00 EDT 2017
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Drug delivery
Hu JB,Song GL,Liu D,Li SJ,Wu JH,Kang XQ,Qi J,Jin FY,Wang XJ,Xu XL,Ying XY,Yu L,You J,Du YZ
Wed Nov 01 00:00:00 EDT 2017
Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.
Drug delivery
Hu JB,Song GL,Liu D,Li SJ,Wu JH,Kang XQ,Qi J,Jin FY,Wang XJ,Xu XL,Ying XY,Yu L,You J,Du YZ
Wed Nov 01 00:00:00 EDT 2017
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Expert opinion on therapeutic targets
Wang X,Tian X,Yang Y,Lu X,Li Y,Ma Y,Zhang Y,Zheng F,Lu S,Xu D,Xu X,Wang W,Wang X
Fri Dec 01 00:00:00 EST 2017
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Expert opinion on therapeutic targets
Wang X,Tian X,Yang Y,Lu X,Li Y,Ma Y,Zhang Y,Zheng F,Lu S,Xu D,Xu X,Wang W,Wang X
Fri Dec 01 00:00:00 EST 2017
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Frontiers in plant science
Zheng L,Shockey J,Bian F,Chen G,Shan L,Li X,Wan S,Peng Z
Wed Sep 30 00:00:00 EDT 2020
Variant Amino Acid Residues Alter the Enzyme Activity of Peanut Type 2 Diacylglycerol Acyltransferases.
Frontiers in plant science
Zheng L,Shockey J,Bian F,Chen G,Shan L,Li X,Wan S,Peng Z
Wed Sep 30 00:00:00 EDT 2020
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Oncogenesis
Zuo LL,Zhang J,Liu LZ,Zhou Q,Du SJ,Xin SY,Ning ZP,Yang J,Yu HB,Yue WX,Wang J,Zhu FX,Li GY,Lu JH
Fri Dec 22 00:00:00 EST 2017
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma.
Oncogenesis
Zuo LL,Zhang J,Liu LZ,Zhou Q,Du SJ,Xin SY,Ning ZP,Yang J,Yu HB,Yue WX,Wang J,Zhu FX,Li GY,Lu JH
Fri Dec 22 00:00:00 EST 2017
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Frontiers in molecular neuroscience
Yu H,Zheng J,Liu X,Xue Y,Shen S,Zhao L,Li Z,Liu Y
Wed Sep 30 00:00:00 EDT 2020
Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change.
Frontiers in molecular neuroscience
Yu H,Zheng J,Liu X,Xue Y,Shen S,Zhao L,Li Z,Liu Y
Wed Sep 30 00:00:00 EDT 2020
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Journal of agricultural and food chemistry
Zhang J,Zhu Y,Shi Y,Han Y,Liang C,Feng Z,Zheng H,Eng M,Wang J
Wed Oct 11 00:00:00 EDT 2017
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Journal of agricultural and food chemistry
Zhang J,Zhu Y,Shi Y,Han Y,Liang C,Feng Z,Zheng H,Eng M,Wang J
Wed Oct 11 00:00:00 EDT 2017
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
International journal of oncology
Huang T,Wang L,Liu D,Li P,Xiong H,Zhuang L,Sun L,Yuan X,Qiu H
Mon May 01 00:00:00 EDT 2017
FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
International journal of oncology
Huang T,Wang L,Liu D,Li P,Xiong H,Zhuang L,Sun L,Yuan X,Qiu H
Mon May 01 00:00:00 EDT 2017
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
International journal of oncology
Liu Y,Zhang C,Zhao L,Du N,Hou N,Song T,Huang C
Sun Oct 01 00:00:00 EDT 2017
APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation.
International journal of oncology
Liu Y,Zhang C,Zhao L,Du N,Hou N,Song T,Huang C
Sun Oct 01 00:00:00 EDT 2017
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
International journal of molecular medicine
Sun L,Chen S,Gao H,Ren L,Song G
Fri Sep 01 00:00:00 EDT 2017
Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway.
International journal of molecular medicine
Sun L,Chen S,Gao H,Ren L,Song G
Fri Sep 01 00:00:00 EDT 2017
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca2+ /K+ channel flow.
Journal of cellular and molecular medicine
Su J,Zhou H,Liu X,Nilsson J,Fredrikson GN,Zhao M
Mon May 01 00:00:00 EDT 2017
oxLDL antibody inhibits MCP-1 release in monocytes/macrophages by regulating Ca2+ /K+ channel flow.
Journal of cellular and molecular medicine
Su J,Zhou H,Liu X,Nilsson J,Fredrikson GN,Zhao M
Mon May 01 00:00:00 EDT 2017
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Human molecular genetics
Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J
Fri Dec 15 00:00:00 EST 2017
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Human molecular genetics
Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J
Fri Dec 15 00:00:00 EST 2017
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Human molecular genetics
Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J
Fri Dec 15 00:00:00 EST 2017
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
Cancer biology & therapy
Ma Q,Zhang Y,Liu T,Jiang K,Wen Y,Fan Q,Qiu X
Sat Mar 04 00:00:00 EST 2017
Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
Cancer biology & therapy
Ma Q,Zhang Y,Liu T,Jiang K,Wen Y,Fan Q,Qiu X
Sat Mar 04 00:00:00 EST 2017
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
The Journal of pharmacy and pharmacology
Xu YY,Xu YS,Wang Y,Wu Q,Lu YF,Liu J,Shi JS
Sun Oct 01 00:00:00 EDT 2017
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
The Journal of pharmacy and pharmacology
Xu YY,Xu YS,Wang Y,Wu Q,Lu YF,Liu J,Shi JS
Sun Oct 01 00:00:00 EDT 2017
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Translational oncology
Wu H,Chen J,Li D,Liu X,Li L,Wang K
Fri Dec 01 00:00:00 EST 2017
MicroRNA-30e Functions as a Tumor Suppressor in Cervical Carcinoma Cells through Targeting GALNT7.
Translational oncology
Wu H,Chen J,Li D,Liu X,Li L,Wang K
Fri Dec 01 00:00:00 EST 2017
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
RNA biology
Chen Z,Luo J,Sun S,Cao D,Shi H,Loor JJ
Sat Mar 04 00:00:00 EST 2017
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
RNA biology
Chen Z,Luo J,Sun S,Cao D,Shi H,Loor JJ
Sat Mar 04 00:00:00 EST 2017
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Cell biology international
Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z
Fri Dec 01 00:00:00 EST 2017
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Cell biology international
Song Y,Kong L,Sun B,Gao L,Chu P,Ahsan A,Qaed E,Lin Y,Peng J,Ma X,Zhang J,Wang S,Tang Z
Fri Dec 01 00:00:00 EST 2017
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Neurochemical research
Yang Z,Geng Y,Yao Z,Jia H,Bai Y,Wang W
Wed Nov 01 00:00:00 EDT 2017
Spatiotemporal Expression of Bcl-2/Bax and Neural Cell Apoptosis in the Developing Lumbosacral Spinal Cord of Rat Fetuses with Anorectal Malformations.
Neurochemical research
Yang Z,Geng Y,Yao Z,Jia H,Bai Y,Wang W
Wed Nov 01 00:00:00 EDT 2017
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
OncoTargets and therapy
Wang Q,Jiang S,Song A,Hou S,Wu Q,Qi L,Gao X
Wed Mar 30 00:00:00 EDT 2022
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a.
OncoTargets and therapy
Wang Q,Jiang S,Song A,Hou S,Wu Q,Qi L,Gao X
Wed Mar 30 00:00:00 EDT 2022
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Toxicology letters
Yang J,Qiao L,Zeng Z,Wang J,Zhu T,Wei J,Wu M,Ye S,Huang X,Ma D,Liu R,Gao Q
Wed Jan 04 00:00:00 EST 2017
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Experimental cell research
Cheng Q,Yuan Y,Li L,Guo T,Miao Y,Ren Y,Liu J,Feng Q,Wang X,Zhao P,Zuo Y,Qian L,Zhang L,Zheng H
Sat Jul 01 00:00:00 EDT 2017
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Experimental cell research
Cheng Q,Yuan Y,Li L,Guo T,Miao Y,Ren Y,Liu J,Feng Q,Wang X,Zhao P,Zuo Y,Qian L,Zhang L,Zheng H
Sat Jul 01 00:00:00 EDT 2017
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Oncology reports
Liang R,Lin Y,Ye JZ,Yan XX,Liu ZH,Li YQ,Luo XL,Ye HH
Sat Apr 01 00:00:00 EDT 2017
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma.
Oncology reports
Liang R,Lin Y,Ye JZ,Yan XX,Liu ZH,Li YQ,Luo XL,Ye HH
Sat Apr 01 00:00:00 EDT 2017
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Oncology reports
Wu S,Zhou Y,Yang G,Tian H,Geng Y,Hu Y,Lin K,Wu W
Mon May 01 00:00:00 EDT 2017
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Oncology reports
Wu S,Zhou Y,Yang G,Tian H,Geng Y,Hu Y,Lin K,Wu W
Mon May 01 00:00:00 EDT 2017
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Bioscience reports
Guo L,Zheng P,Fan H,Wang H,Xu W,Zhou W
Fri Dec 22 00:00:00 EST 2017
Ultrasound reverses chemoresistance in breast cancer stem cell like cells by altering ABCG2 expression.
Bioscience reports
Guo L,Zheng P,Fan H,Wang H,Xu W,Zhou W
Fri Dec 22 00:00:00 EST 2017
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
American journal of translational research
Lian Q,Ma DM,Chen MG,Chen K,Li XJ
Wed Sep 30 00:00:00 EDT 2020
Silencing Rab14 represses the proliferation and migration of oral squamous cell carcinoma, and enhances cisplatin sensitivity.
American journal of translational research
Lian Q,Ma DM,Chen MG,Chen K,Li XJ
Wed Sep 30 00:00:00 EDT 2020
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
American journal of translational research
Pan X,Zhang R,Xie C,Gan M,Yao S,Yao Y,Jin J,Han T,Huang Y,Gong Y,Wang J,Yu B
Wed Sep 30 00:00:00 EDT 2020
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
American journal of translational research
Pan X,Zhang R,Xie C,Gan M,Yao S,Yao Y,Jin J,Han T,Huang Y,Gong Y,Wang J,Yu B
Wed Sep 30 00:00:00 EDT 2020
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Gene
Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y
Mon Oct 30 00:00:00 EDT 2017
The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression.
Gene
Liu Y,Zong ZH,Guan X,Wang LL,Zhao Y
Mon Oct 30 00:00:00 EDT 2017
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Pharmaceutical biology
Zhao X,Chen Z,Yin Y,Li X
Fri Dec 01 00:00:00 EST 2017
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Pharmaceutical biology
Zhao X,Chen Z,Yin Y,Li X
Fri Dec 01 00:00:00 EST 2017
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Drug metabolism and disposition: the biological fate of chemicals
Scott F,Gonzalez Malagon SG,O'Brien BA,Fennema D,Veeravalli S,Coveney CR,Phillips IR,Shephard EA
Fri Sep 01 00:00:00 EDT 2017
Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.
Drug metabolism and disposition: the biological fate of chemicals
Scott F,Gonzalez Malagon SG,O'Brien BA,Fennema D,Veeravalli S,Coveney CR,Phillips IR,Shephard EA
Fri Sep 01 00:00:00 EDT 2017
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Biochemical and biophysical research communications
Liu D,Qiu XY,Wu X,Hu DX,Li CY,Yu SB,Pan F,Chen XQ
Sat Dec 09 00:00:00 EST 2017
Piperlongumine suppresses bladder cancer invasion via inhibiting epithelial mesenchymal transition and F-actin reorganization.
Biochemical and biophysical research communications
Liu D,Qiu XY,Wu X,Hu DX,Li CY,Yu SB,Pan F,Chen XQ
Sat Dec 09 00:00:00 EST 2017
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Biochemical and biophysical research communications
Tang J,Dong Q
Sun Jan 22 00:00:00 EST 2017
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Biochemical and biophysical research communications
Tang J,Dong Q
Sun Jan 22 00:00:00 EST 2017
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Veterinary microbiology
Yu J,Zhu YH,Yang GY,Zhang W,Zhou D,Su JH,Wang JF
Sun Oct 01 00:00:00 EDT 2017
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Veterinary microbiology
Yu J,Zhu YH,Yang GY,Zhang W,Zhou D,Su JH,Wang JF
Sun Oct 01 00:00:00 EDT 2017
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Oncology letters
Yuan Y,Du Y,Hu XY,Liu MY,Du JK,Liu XM,Yu HE,Wang TZ,Pu JX,Zhong Q,Zou QF
Wed Mar 01 00:00:00 EST 2017
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells.
Oncology letters
Yuan Y,Du Y,Hu XY,Liu MY,Du JK,Liu XM,Yu HE,Wang TZ,Pu JX,Zhong Q,Zou QF
Wed Mar 01 00:00:00 EST 2017
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Experimental and therapeutic medicine
Tang Z,Zhang Z,Tang Y,Qi L,Yang F,Wang Z
Fri Dec 01 00:00:00 EST 2017
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Experimental and therapeutic medicine
Tang Z,Zhang Z,Tang Y,Qi L,Yang F,Wang Z
Fri Dec 01 00:00:00 EST 2017
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Experimental and therapeutic medicine
Liu J,Song G,Lin X,Pang X,Meng T
Sat Apr 01 00:00:00 EDT 2017
Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells.
Experimental and therapeutic medicine
Liu J,Song G,Lin X,Pang X,Meng T
Sat Apr 01 00:00:00 EDT 2017
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Audiology & neuro-otology
Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H
Fri Jul 27 00:00:00 EDT 2018
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Audiology & neuro-otology
Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H
Fri Jul 27 00:00:00 EDT 2018
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
European journal of histochemistry : EJH
Liu J,Cai L,He Y,Yang J
Mon Aug 07 00:00:00 EDT 2017
Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker's organ in vivo in early stage after birth in rats.
European journal of histochemistry : EJH
Liu J,Cai L,He Y,Yang J
Mon Aug 07 00:00:00 EDT 2017
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Medicine
Zhang Y,Huang J,Yang X,Sun X,Xu Q,Wang B,Zhong P,Wei Z
Fri Dec 01 00:00:00 EST 2017
Altered Expression of TXNIP in the peripheral leukocytes of patients with coronary atherosclerotic heart disease.
Medicine
Zhang Y,Huang J,Yang X,Sun X,Xu Q,Wang B,Zhong P,Wei Z
Fri Dec 01 00:00:00 EST 2017
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Journal of neuroinflammation
Jiang P,Guo Y,Dang R,Yang M,Liao D,Li H,Sun Z,Feng Q,Xu P
Wed Dec 06 00:00:00 EST 2017
Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome.
Journal of neuroinflammation
Jiang P,Guo Y,Dang R,Yang M,Liao D,Li H,Sun Z,Feng Q,Xu P
Wed Dec 06 00:00:00 EST 2017
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Stem cell reviews and reports
Jin Y,Xu L,Zhao Y,Wang M,Jin X,Zhang H
Sat Apr 01 00:00:00 EDT 2017
Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction.
Stem cell reviews and reports
Jin Y,Xu L,Zhao Y,Wang M,Jin X,Zhang H
Sat Apr 01 00:00:00 EDT 2017
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Oncotarget
Wu G,Li Z,Jiang P,Zhang X,Xu Y,Chen K,Li X
Tue Oct 10 00:00:00 EDT 2017
Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.
Chinese journal of integrative medicine
Ni JN,Shi J,Zhang XK,Yang YC,Liu XM,Wei MQ,Li T,Wang PW,Tian JZ,Wang YY
Tue Aug 01 00:00:00 EDT 2017
Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.
Development (Cambridge, England)
Shao M,Wang M,Liu YY,Ge YW,Zhang YJ,Shi DL
Fri Sep 15 00:00:00 EDT 2017
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.
Chemical science
Zhang L,Fu L,Zhang S,Zhang J,Zhao Y,Zheng Y,He G,Yang S,Ouyang L,Liu B
Sat Apr 01 00:00:00 EDT 2017
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Biochemical and biophysical research communications
Yang F,Shi L,Liang T,Ji L,Zhang G,Shen Y,Zhu F,Xu L
Sat Mar 25 00:00:00 EDT 2017
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Oncotarget
Xue C,Wang C,Sun Y,Meng Q,Liu Z,Huo X,Sun P,Sun H,Ma X,Ma X,Peng J,Liu K
Tue Jan 31 00:00:00 EST 2017
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Cell death & disease
Li S,Wu Z,Ma P,Xu Y,Chen Y,Wang H,He P,Kang Z,Yin L,Zhao Y,Zhang X,Xu X,Ma X,Guan M
Thu Oct 12 00:00:00 EDT 2017
Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression.
Cell death & disease
Li S,Wu Z,Ma P,Xu Y,Chen Y,Wang H,He P,Kang Z,Yin L,Zhao Y,Zhang X,Xu X,Ma X,Guan M
Thu Oct 12 00:00:00 EDT 2017
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
Medical science monitor : international medical journal of experimental and clinical research
Liu Z,Yu J,Wu R,Tang S,Cai X,Guo G,Chen S
Sat Dec 30 00:00:00 EST 2017
Rho/ROCK Pathway Regulates Migration and Invasion of Esophageal Squamous Cell Carcinoma by Regulating Caveolin-1.
Medical science monitor : international medical journal of experimental and clinical research
Liu Z,Yu J,Wu R,Tang S,Cai X,Guo G,Chen S
Sat Dec 30 00:00:00 EST 2017
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang M,Zhang Y,Wang T,Zhang J,Zhou Z,Sun Y,Wang S,Shi Y,Luan X,Zhang Y,Wang Y,Wang Y,Zou Z,Kang L,Liu H
Mon Jan 22 00:00:00 EST 2018
The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang M,Zhang Y,Wang T,Zhang J,Zhou Z,Sun Y,Wang S,Shi Y,Luan X,Zhang Y,Wang Y,Wang Y,Zou Z,Kang L,Liu H
Mon Jan 22 00:00:00 EST 2018
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Frontiers in neuroscience
Liu Z,Cui C,Xu P,Dang R,Cai H,Liao D,Yang M,Feng Q,Yan X,Jiang P
Thu Oct 01 00:00:00 EDT 2020
Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.
Frontiers in neuroscience
Liu Z,Cui C,Xu P,Dang R,Cai H,Liao D,Yang M,Feng Q,Yan X,Jiang P
Thu Oct 01 00:00:00 EDT 2020
Ontogeny, aging, and gender-related changes in hepatic multidrug resistant protein genes in rats.
Life sciences
Zhu QN,Hou WY,Xu SF,Lu YF,Liu J
Wed Feb 01 00:00:00 EST 2017
Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Down-Regulation of Protein Tyrosine Phosphatase 1B in Obese Rats.
Obesity facts
Mu S,Liu J,Guo W,Zhang S,Xiao X,Wang Z,Zhang J
Tue Jan 09 00:00:00 EST 2018
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
He Y,Pan S,Xu M,He R,Huang W,Song P,Huang J,Zhang HT,Hu Y
Tue Aug 01 00:00:00 EDT 2017
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nature communications
Wu G,Yuan M,Shen S,Ma X,Fang J,Zhu L,Sun L,Liu Z,He X,Huang D,Li T,Li C,Wu J,Hu X,Li Z,Song L,Qu K,Zhang H,Gao P
Fri May 05 00:00:00 EDT 2017
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nature communications
Wu G,Yuan M,Shen S,Ma X,Fang J,Zhu L,Sun L,Liu Z,He X,Huang D,Li T,Li C,Wu J,Hu X,Li Z,Song L,Qu K,Zhang H,Gao P
Fri May 05 00:00:00 EDT 2017
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
Scientific reports
Qiang G,Whang Kong H,Gil V,Liew CW
Mon Jan 09 00:00:00 EST 2017
Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.
Scientific reports
Qiang G,Whang Kong H,Gil V,Liew CW
Mon Jan 09 00:00:00 EST 2017
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
BMC cancer
Chang CH,Liu WT,Hung HC,Gean CY,Tsai HM,Su CL,Gean PW
Fri Dec 29 00:00:00 EST 2017
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
BMC cancer
Chang CH,Liu WT,Hung HC,Gean CY,Tsai HM,Su CL,Gean PW
Fri Dec 29 00:00:00 EST 2017
Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation.
International journal of cancer
Wang X,Cheng Y,Zhu Y,Li H,Ge W,Wu X,Zhao K,Yuan J,Li Z,Jiang S,Han Z,Jiang Q,Wu Q,Liu T,Zhang C,Yu M,Hu Y
Sun Oct 01 00:00:00 EDT 2017
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
International journal of molecular medicine
He G,Yang L,Qian X,Li J,Yuan Z,Li C
Thu Jun 01 00:00:00 EDT 2017
Paper/PMMA Hybrid 3D Cell Culture Microfluidic Platform for the Study of Cellular Crosstalk.
ACS applied materials & interfaces
Lei KF,Chang CH,Chen MJ
Wed Apr 19 00:00:00 EDT 2017
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
Oncotarget
Wang S,Tan X,Li S,Zhou Y,Geng P,Hua A,Deng A,Yu Z
Tue Dec 19 00:00:00 EST 2017
Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.
Oncotarget
Wang S,Tan X,Li S,Zhou Y,Geng P,Hua A,Deng A,Yu Z
Tue Dec 19 00:00:00 EST 2017
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Oncotarget
Wang Y,Zhao H,Shao Y,Liu J,Li J,Xing M
Fri Nov 17 00:00:00 EST 2017
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Oncotarget
Wang Y,Zhao H,Shao Y,Liu J,Li J,Xing M
Fri Nov 17 00:00:00 EST 2017
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
International journal of molecular sciences
Tang Z,Liu N,Luo L,Kang K,Li L,Ni R,Qiu H,Gou D
Fri Mar 31 00:00:00 EDT 2017
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
International journal of molecular sciences
Tang Z,Liu N,Luo L,Kang K,Li L,Ni R,Qiu H,Gou D
Fri Mar 31 00:00:00 EDT 2017
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Scientific reports
Zhao X,Sun K,Lan Z,Song W,Cheng L,Chi W,Chen J,Huo Y,Xu L,Liu X,Deng H,Siegenthaler JA,Chen L
Tue Apr 11 00:00:00 EDT 2017
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Scientific reports
Zhao X,Sun K,Lan Z,Song W,Cheng L,Chi W,Chen J,Huo Y,Xu L,Liu X,Deng H,Siegenthaler JA,Chen L
Tue Apr 11 00:00:00 EDT 2017
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Oncotarget
Wei X,Ye J,Shang Y,Chen H,Liu S,Liu L,Wang R
Tue Dec 12 00:00:00 EST 2017
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Oncotarget
Wei X,Ye J,Shang Y,Chen H,Liu S,Liu L,Wang R
Tue Dec 12 00:00:00 EST 2017
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zuo T,Zhu M,Xu W,Wang Z,Song H
Mon Jan 22 00:00:00 EST 2018
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zuo T,Zhu M,Xu W,Wang Z,Song H
Mon Jan 22 00:00:00 EST 2018
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Oncotarget
Han T,Guo M,Zhang T,Gan M,Xie C,Wang JB
Tue Apr 25 00:00:00 EDT 2017
Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development.
Current molecular medicine
Chen F,Yuan W,Mo X,Zhuang J,Wang Y,Chen J,Jiang Z,Zhu X,Zeng Q,Wan Y,Li F,Shi Y,Cao L,Fan X,Luo S,Ye X,Chen Y,Dai G,Gao J,Wang X,Xie H,Zhu P,Li Y,Wu X
Tue Jun 11 00:00:00 EDT 2019
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
NPJ Parkinson's disease
Cording AC,Shiaelis N,Petridi S,Middleton CA,Wilson LG,Elliott CJH
Sat Jan 29 00:00:00 EST 2022
Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.
NPJ Parkinson's disease
Cording AC,Shiaelis N,Petridi S,Middleton CA,Wilson LG,Elliott CJH
Sat Jan 29 00:00:00 EST 2022
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
PloS one
Mei LL,Wang WJ,Qiu YT,Xie XF,Bai J,Shi ZZ
Tue Oct 31 00:00:00 EDT 2017
miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
PloS one
Mei LL,Wang WJ,Qiu YT,Xie XF,Bai J,Shi ZZ
Tue Oct 31 00:00:00 EDT 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Lv C,Maharjan S,Wang Q,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B
Tue Dec 26 00:00:00 EST 2017
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1.
Gene
Zhang R,Wang M,Sui P,Ding L,Yang Q
Mon Mar 20 00:00:00 EDT 2017
Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules.
Oncotarget
Chen Z,Niu M,Sun M,Yuan Q,Yao C,Hou J,Wang H,Wen L,Fu H,Zhou F,Li Z,He Z
Tue Feb 28 00:00:00 EST 2017
Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling.
Oncotarget
Yang X,Ye X,Sun L,Gao F,Li Y,Ji X,Wang X,Feng Y,Wang X
Fri Sep 22 00:00:00 EDT 2017
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Cell death & disease
Wu J,Tian Z,Sun Y,Lu C,Liu N,Gao Z,Zhang L,Dong S,Yang F,Zhong X,Xu C,Lu F,Zhang W
Thu Aug 10 00:00:00 EDT 2017
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Cell death & disease
Wu J,Tian Z,Sun Y,Lu C,Liu N,Gao Z,Zhang L,Dong S,Yang F,Zhong X,Xu C,Lu F,Zhang W
Thu Aug 10 00:00:00 EDT 2017
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Frontiers in microbiology
Zhang Q,Sun J,Wang Y,He W,Wang L,Zheng Y,Wu J,Zhang Y,Jiang X
Tue Sep 29 00:00:00 EDT 2020
Antimycobacterial and Anti-inflammatory Mechanisms of Baicalin via Induced Autophagy in Macrophages Infected with Mycobacterium tuberculosis.
Frontiers in microbiology
Zhang Q,Sun J,Wang Y,He W,Wang L,Zheng Y,Wu J,Zhang Y,Jiang X
Tue Sep 29 00:00:00 EDT 2020
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Molecular medicine reports
Yan B,Ma Z,Shi S,Hu Y,Ma T,Rong G,Yang J
Thu Jun 01 00:00:00 EDT 2017
Glucose potentiates β-cell function by inducing Tph1 expression in rat islets.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Y,Deng R,Yang X,Xu W,Liu Y,Li F,Zhang J,Tang H,Ji X,Bi Y,Wang X,Zhou L,Ning G
Fri Dec 01 00:00:00 EST 2017
Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.
Inflammation
Xing T,Wang Y,Ding WJ,Li YL,Hu XD,Wang C,Ding A,Shen JL
Sun Oct 01 00:00:00 EDT 2017
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
The international journal of neuropsychopharmacology
Liu SY,Li D,Zeng HY,Kan LY,Zou W,Zhang P,Gu HF,Tang XQ
Wed Nov 01 00:00:00 EDT 2017
Ovarian cancer proliferation and apoptosis are regulated by human transfer RNA methyltransferase 9-likevia LIN9.
Oncology letters
Chen HM,Wang J,Zhang YF,Gao YH
Sun Oct 01 00:00:00 EDT 2017
Regulation of AMH by oocyte-specific growth factors in human primary cumulus cells.
Reproduction (Cambridge, England)
Convissar S,Armouti M,Fierro MA,Winston NJ,Scoccia H,Zamah AM,Stocco C
Fri Dec 01 00:00:00 EST 2017
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
The Journal of biological chemistry
Yao P,Sun H,Xu C,Chen T,Zou B,Jiang P,Du W
Fri Oct 13 00:00:00 EDT 2017
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
The Journal of biological chemistry
Yao P,Sun H,Xu C,Chen T,Zou B,Jiang P,Du W
Fri Oct 13 00:00:00 EDT 2017
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
International journal of molecular sciences
Zhang Y,Ren S,Liu Y,Gao K,Liu Z,Zhang Z
Sat Oct 14 00:00:00 EDT 2017
Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2.
International journal of molecular sciences
Zhang Y,Ren S,Liu Y,Gao K,Liu Z,Zhang Z
Sat Oct 14 00:00:00 EDT 2017
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Scientific reports
Xue L,He J,Gao N,Lu X,Li M,Wu X,Liu Z,Jin Y,Liu J,Xu J,Geng Y
Tue Mar 28 00:00:00 EDT 2017
Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia.
Scientific reports
Xue L,He J,Gao N,Lu X,Li M,Wu X,Liu Z,Jin Y,Liu J,Xu J,Geng Y
Tue Mar 28 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu J,Wang L,Du Y,Liu S
Sun Oct 01 00:00:00 EDT 2017
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
International journal of nanomedicine
Wang GD,Tan YZ,Wang HJ,Zhou P
Mon Dec 25 00:00:00 EST 2017
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.
International journal of nanomedicine
Wang GD,Tan YZ,Wang HJ,Zhou P
Mon Dec 25 00:00:00 EST 2017
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Oncotarget
Zeng HL,Yang Q,Du H,Li H,Shen Y,Liu T,Chen X,Kamal GM,Guan Q,Cheng L,Wang J,Xu F
Fri Nov 24 00:00:00 EST 2017
Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats.
Oncotarget
Zeng HL,Yang Q,Du H,Li H,Shen Y,Liu T,Chen X,Kamal GM,Guan Q,Cheng L,Wang J,Xu F
Fri Nov 24 00:00:00 EST 2017
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Marine drugs
Sun X,Zhong Y,Luo H,Yang Y
Sun Jul 16 00:00:00 EDT 2017
Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
Marine drugs
Sun X,Zhong Y,Luo H,Yang Y
Sun Jul 16 00:00:00 EDT 2017
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Duan X,Meng Q,Wang C,Liu Z,Liu Q,Sun H,Sun P,Yang X,Huo X,Peng J,Liu K
Wed Feb 15 00:00:00 EST 2017
AMPK/α-Ketoglutarate Axis Regulates Intestinal Water and Ion Homeostasis in Young Pigs.
Journal of agricultural and food chemistry
He L,Huang N,Li H,Tian J,Zhou X,Li T,Yao K,Wu G,Yin Y
Wed Mar 22 00:00:00 EDT 2017
NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide.
Oncotarget
Zhang X,Kang T,Zhang L,Tong Y,Ding W,Chen S
Tue Aug 08 00:00:00 EDT 2017
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Molecular and cellular endocrinology
Li Y,Wang L,Zhou L,Song Y,Ma S,Yu C,Zhao J,Xu C,Gao L
Fri May 05 00:00:00 EDT 2017
CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis.
Molecular biology reports
Tang M,Shi C,Song B,Yang J,Yang T,Mao C,Li Y,Liu X,Zhang S,Wang H,Luo H,Xu Y
Sat Jul 01 00:00:00 EDT 2017
High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.
The International journal of biological markers
Guo C,Ouyang Y,Cai J,Xiong L,Chen Y,Zeng X,Liu A
Tue Oct 31 00:00:00 EDT 2017
Paeoniflorin attenuates incipient diabetic nephropathy in streptozotocin-induced mice by the suppression of the Toll-like receptor-2 signaling pathway.
Drug design, development and therapy
Shao YX,Xu XX,Wang K,Qi XM,Wu YG
Mon Jul 23 00:00:00 EDT 2018
Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the JAK/STAT3 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang Y,Lu HL,Liu YD,Yang LY,Jiang QK,Zhu XJ,Fan HN,Qian Y
Wed Nov 01 00:00:00 EDT 2017
Cerebrolysin alleviates cognitive deficits induced by chronic cerebral hypoperfusion by increasing the levels of plasticity-related proteins and decreasing the levels of apoptosis-related proteins in the rat hippocampus.
Neuroscience letters
Liu Z,Hu M,Lu P,Wang H,Qi Q,Xu J,Xiao Y,Fan M,Jia Y,Zhang D
Fri Jun 09 00:00:00 EDT 2017
Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
The Journal of biological chemistry
Qi J,Lee HJ,Saquet A,Cheng XN,Shao M,Zheng JJ,Shi DL
Fri Apr 07 00:00:00 EDT 2017
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Frontiers in pharmacology
Tao B,Wang R,Sun C,Zhu Y
Wed Sep 30 00:00:00 EDT 2020
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.
Frontiers in pharmacology
Tao B,Wang R,Sun C,Zhu Y
Wed Sep 30 00:00:00 EDT 2020
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
PloS one
Zhang Z,Zheng F,Yu Z,Hao J,Chen M,Yu W,Guo W,Chen Y,Huang W,Duan Z,Deng W
Mon Nov 20 00:00:00 EST 2017
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
PloS one
Zhang Z,Zheng F,Yu Z,Hao J,Chen M,Yu W,Guo W,Chen Y,Huang W,Duan Z,Deng W
Mon Nov 20 00:00:00 EST 2017
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
International journal of obesity (2005)
Gao Y,Li J,Xu X,Wang S,Yang Y,Zhou J,Zhang L,Zheng F,Li X,Wang B
Mon May 01 00:00:00 EDT 2017
Inhibition of tissue transglutaminase attenuates lipopolysaccharide-induced inflammation in glial cells through AKT/mTOR signal pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ding Y,Zhang J,Wang R
Mon May 01 00:00:00 EDT 2017
The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Nature cell biology
Yuan JH,Liu XN,Wang TT,Pan W,Tao QF,Zhou WP,Wang F,Sun SH
Sat Jul 01 00:00:00 EDT 2017
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts.
Journal of photochemistry and photobiology. B, Biology
Petruk G,Illiano A,Del Giudice R,Raiola A,Amoresano A,Rigano MM,Piccoli R,Monti DM
Sat Jul 01 00:00:00 EDT 2017
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Chen J,Liu H,Gao P,Hui Y,Yang Z,Zhang X,Xu P,Tian F,Fan T
Mon May 01 00:00:00 EDT 2017
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Nature genetics
Zheng J,Huang X,Tan W,Yu D,Du Z,Chang J,Wei L,Han Y,Wang C,Che X,Zhou Y,Miao X,Jiang G,Yu X,Yang X,Cao G,Zuo C,Li Z,Wang C,Cheung ST,Jia Y,Zheng X,Shen H,Wu C,Lin D
Fri Jul 01 00:00:00 EDT 2016
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Nature genetics
Zheng J,Huang X,Tan W,Yu D,Du Z,Chang J,Wei L,Han Y,Wang C,Che X,Zhou Y,Miao X,Jiang G,Yu X,Yang X,Cao G,Zuo C,Li Z,Wang C,Cheung ST,Jia Y,Zheng X,Shen H,Wu C,Lin D
Fri Jul 01 00:00:00 EDT 2016
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Nucleic acids research
Lyons SM,Achorn C,Kedersha NL,Anderson PJ,Ivanov P
Fri Aug 19 00:00:00 EDT 2016
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Nucleic acids research
Lyons SM,Achorn C,Kedersha NL,Anderson PJ,Ivanov P
Fri Aug 19 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
Experimental cell research
Chen Z,Shi H,Sun S,Xu H,Cao D,Luo J
Sat Oct 15 00:00:00 EDT 2016
MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway.
Experimental cell research
Chen Z,Shi H,Sun S,Xu H,Cao D,Luo J
Sat Oct 15 00:00:00 EDT 2016
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Molecular medicine reports
Liu L,Li D,Chen S,Zhao R,Pang D,Li D,Fu Z
Thu Sep 01 00:00:00 EDT 2016
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Molecular medicine reports
Liu L,Li D,Chen S,Zhao R,Pang D,Li D,Fu Z
Thu Sep 01 00:00:00 EDT 2016
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
Steroids
Dang R,Guo Y,Zhang L,Chen L,Yang R,Jiang P
Mon Aug 01 00:00:00 EDT 2016
Chronic stress and excessive glucocorticoid exposure both lead to altered Neuregulin-1/ErbB signaling in rat myocardium.
Steroids
Dang R,Guo Y,Zhang L,Chen L,Yang R,Jiang P
Mon Aug 01 00:00:00 EDT 2016
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Experimental and therapeutic medicine
Tai Y,Sun YM,Zou X,Pan Q,Lan YD,Huo Q,Zhu JW,Guo F,Zheng CQ,Wu CZ,Liu H
Sat Oct 01 00:00:00 EDT 2016
Effect of Polygonatum odoratum extract on human breast cancer MDA-MB-231 cell proliferation and apoptosis.
Experimental and therapeutic medicine
Tai Y,Sun YM,Zou X,Pan Q,Lan YD,Huo Q,Zhu JW,Guo F,Zheng CQ,Wu CZ,Liu H
Sat Oct 01 00:00:00 EDT 2016
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Lasers in medical science
Hu B,Song Z,Liu H,Qiao L,Zhao Y,Wang M,Song W,Zhang D,Jin X,Zhang H
Tue Nov 01 00:00:00 EDT 2016
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Lasers in medical science
Hu B,Song Z,Liu H,Qiao L,Zhao Y,Wang M,Song W,Zhang D,Jin X,Zhang H
Tue Nov 01 00:00:00 EDT 2016
Protective effect of melatonin on myenteric neuron damage in experimental colitis in rats.
Fundamental & clinical pharmacology
Shang B,Shi H,Wang X,Guo X,Wang N,Wang Y,Dong L
Fri Apr 01 00:00:00 EDT 2016
Valsartan Attenuates KIR2.1 by Downregulating the Th1 Immune Response in Rats Following Myocardial Infarction.
Journal of cardiovascular pharmacology
Li X,Hu H,Wang Y,Xue M,Li X,Cheng W,Xuan Y,Yin J,Yang N,Yan S
Tue Mar 01 00:00:00 EST 2016
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
The Journal of biological chemistry
Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H
Fri Nov 25 00:00:00 EST 2016
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
The Journal of biological chemistry
Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H
Fri Nov 25 00:00:00 EST 2016
The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats.
Peptides
Gao J,Bai T,Ren L,Ding Y,Zhong X,Wang H,Guo Y,Li J,Liu Y,Zhang Y
Thu Dec 01 00:00:00 EST 2016
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Oncotarget
Zhao S,Li L,Wang S,Yu C,Xiao B,Lin L,Cong W,Cheng J,Yang W,Sun W,Cui S
Tue Dec 20 00:00:00 EST 2016
HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death.
Oncotarget
Wang HX,Yang Y,Guo H,Hou DD,Zheng S,Hong YX,Cai YF,Huo W,Qi RQ,Zhang L,Chen HD,Gao XH
Tue Oct 11 00:00:00 EDT 2016
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Aging cell
Han X,Tai H,Wang X,Wang Z,Zhou J,Wei X,Ding Y,Gong H,Mo C,Zhang J,Qin J,Ma Y,Huang N,Xiang R,Xiao H
Wed Jun 01 00:00:00 EDT 2016
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
International immunopharmacology
Xu X,Fan Z,Qi X,Shao Y,Wu Y
Thu Sep 01 00:00:00 EDT 2016
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ge G,Zhou C,Ren Y,Tang X,Wang K,Zhang W,Niu L,Zhou Y,Yan Y,He J
Fri Apr 01 00:00:00 EDT 2016
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ge G,Zhou C,Ren Y,Tang X,Wang K,Zhang W,Niu L,Zhou Y,Yan Y,He J
Fri Apr 01 00:00:00 EDT 2016
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
Journal of translational medicine
Sun W,Gui L,Zuo X,Zhang L,Zhou D,Duan X,Ren W,Xu G
Wed Mar 16 00:00:00 EDT 2016
Human epithelial-type ovarian tumour marker beta-2-microglobulin is regulated by the TGF-β signaling pathway.
Journal of translational medicine
Sun W,Gui L,Zuo X,Zhang L,Zhou D,Duan X,Ren W,Xu G
Wed Mar 16 00:00:00 EDT 2016
A novel transgenic mouse model of lysosomal storage disorder.
American journal of physiology. Gastrointestinal and liver physiology
Ortiz-Miranda S,Ji R,Jurczyk A,Aryee KE,Mo S,Fletcher T,Shaffer SA,Greiner DL,Bortell R,Gregg RG,Cheng A,Hennings LJ,Rittenhouse AR
Tue Nov 01 00:00:00 EDT 2016
Afamin promotes glucose metabolism in papillary thyroid carcinoma.
Molecular and cellular endocrinology
Shen CT,Wei WJ,Qiu ZL,Song HJ,Luo QY
Sat Oct 15 00:00:00 EDT 2016
Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.
Journal of medicinal chemistry
Jiang F,Wang HJ,Jin YH,Zhang Q,Wang ZH,Jia JM,Liu F,Wang L,Bao QC,Li DD,You QD,Xu XL
Thu Dec 08 00:00:00 EST 2016
Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs.
The Journal of general virology
Chen C,Jia H,Zhang F,Qin Y,Zong L,Yuan Q,Wang Y,Xia N,Li J,Wen Y,Tong S
Sat Oct 01 00:00:00 EDT 2016
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages.
Cytokine
Xu X,Qi X,Shao Y,Li Y,Fu X,Feng S,Wu Y
Mon Feb 01 00:00:00 EST 2016
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Scientific reports
Zhao N,Han D,Liu H,Li Y,Wong SW,Cao Z,Xu J,Zhang X,Cai T,Wang Y,Feng H
Wed Dec 07 00:00:00 EST 2016
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome.
Scientific reports
Zhao N,Han D,Liu H,Li Y,Wong SW,Cao Z,Xu J,Zhang X,Cai T,Wang Y,Feng H
Wed Dec 07 00:00:00 EST 2016
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Lipids in health and disease
Jiang D,Wang D,Zhuang X,Wang Z,Ni Y,Chen S,Sun F
Fri Dec 09 00:00:00 EST 2016
Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway.
Lipids in health and disease
Jiang D,Wang D,Zhuang X,Wang Z,Ni Y,Chen S,Sun F
Fri Dec 09 00:00:00 EST 2016
Foxo3b but not Foxo3a activates cyp19a1a in Epinephelus coioides.
Journal of molecular endocrinology
Liu Q,Zhang Y,Shi B,Lu H,Zhang L,Zhang W
Sun May 01 00:00:00 EDT 2016
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Nature communications
Mao P,Liu J,Zhang Z,Zhang H,Liu H,Gao S,Rong YS,Zhao Y
Mon Jul 11 00:00:00 EDT 2016
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.
Nature communications
Mao P,Liu J,Zhang Z,Zhang H,Liu H,Gao S,Rong YS,Zhao Y
Mon Jul 11 00:00:00 EDT 2016
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Biochimica et biophysica acta
Guan J,Zhao Q,Mao W
Thu Dec 01 00:00:00 EST 2016
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.
Biochimica et biophysica acta
Guan J,Zhao Q,Mao W
Thu Dec 01 00:00:00 EST 2016
Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation.
Oncotarget
Zhong Z,Hu Z,Jiang Y,Sun R,Chen X,Chu H,Zeng M,Sun C
Tue Sep 13 00:00:00 EDT 2016
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
International journal of cancer
Sun Q,Liu T,Yuan Y,Guo Z,Xie G,Du S,Lin X,Xu Z,Liu M,Wang W,Yuan Q,Chen L
Sun Mar 01 00:00:00 EST 2015
MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
International journal of cancer
Sun Q,Liu T,Yuan Y,Guo Z,Xie G,Du S,Lin X,Xu Z,Liu M,Wang W,Yuan Q,Chen L
Sun Mar 01 00:00:00 EST 2015
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Stem cells (Dayton, Ohio)
Pan QZ,Pan K,Wang QJ,Weng DS,Zhao JJ,Zheng HX,Zhang XF,Jiang SS,Lv L,Tang Y,Li YQ,He J,Liu Q,Chen CL,Zhang HX,Xia JC
Sun Feb 01 00:00:00 EST 2015
Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.
Stem cells (Dayton, Ohio)
Pan QZ,Pan K,Wang QJ,Weng DS,Zhao JJ,Zheng HX,Zhang XF,Jiang SS,Lv L,Tang Y,Li YQ,He J,Liu Q,Chen CL,Zhang HX,Xia JC
Sun Feb 01 00:00:00 EST 2015
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Molecular neurobiology
Esteras N,Alquézar C,Bartolomé F,de la Encarnación A,Bermejo-Pareja F,Molina JA,Martín-Requero Á
Sat Aug 01 00:00:00 EDT 2015
G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.
Molecular neurobiology
Esteras N,Alquézar C,Bartolomé F,de la Encarnación A,Bermejo-Pareja F,Molina JA,Martín-Requero Á
Sat Aug 01 00:00:00 EDT 2015
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Song E,Yu W,Xiong X,Kuang X,Ai Y,Xiong X
Sun Mar 01 00:00:00 EST 2015
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
Oncology reports
Xu Y,Wang C,Su J,Xie Q,Ma L,Zeng L,Yu Y,Liu S,Li S,Li Z,Sun L
Tue Dec 01 00:00:00 EST 2015
Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis.
Oncology reports
Xu Y,Wang C,Su J,Xie Q,Ma L,Zeng L,Yu Y,Liu S,Li S,Li Z,Sun L
Tue Dec 01 00:00:00 EST 2015
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Environmental toxicology
Han SP,Zhou DX,Lin P,Qin Z,An L,Zheng LR,Lei L
Sun Mar 01 00:00:00 EST 2015
Formaldehyde exposure induces autophagy in testicular tissues of adult male rats.
Environmental toxicology
Han SP,Zhou DX,Lin P,Qin Z,An L,Zheng LR,Lei L
Sun Mar 01 00:00:00 EST 2015
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
European review for medical and pharmacological sciences
Wang X,Zhao XL,Xu LL,Wang CF,Wei LF,Liu Z,Yang H,Wang P,Xie ZH,Bi JZ
Tue Dec 01 00:00:00 EST 2015
Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells.
European review for medical and pharmacological sciences
Wang X,Zhao XL,Xu LL,Wang CF,Wei LF,Liu Z,Yang H,Wang P,Xie ZH,Bi JZ
Tue Dec 01 00:00:00 EST 2015
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Molecular medicine reports
Meng D,Liu R,Pei L,Hou L,Ning Q,Yu Q,Feng L,Zhao X
Wed Apr 01 00:00:00 EDT 2015
Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells.
Molecular medicine reports
Meng D,Liu R,Pei L,Hou L,Ning Q,Yu Q,Feng L,Zhao X
Wed Apr 01 00:00:00 EDT 2015
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Molecular medicine reports
Sun Q,Liu T,Zhang T,Du S,Xie GX,Lin X,Chen L,Yuan Y
Fri May 01 00:00:00 EDT 2015
MiR-101 sensitizes human nasopharyngeal carcinoma cells to radiation by targeting stathmin 1.
Molecular medicine reports
Sun Q,Liu T,Zhang T,Du S,Xie GX,Lin X,Chen L,Yuan Y
Fri May 01 00:00:00 EDT 2015
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Archives of gynecology and obstetrics
Shen F,Yan C,Liu M,Feng Y,Chen Y
Sun Feb 01 00:00:00 EST 2015
Decreased expression of mucin-1 in endometriosis endometrium correlated with progesterone receptor B involved in infertility.
Archives of gynecology and obstetrics
Shen F,Yan C,Liu M,Feng Y,Chen Y
Sun Feb 01 00:00:00 EST 2015
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Anatomical record (Hoboken, N.J. : 2007)
Yang X,Xiang X,Xia M,Su J,Wu Y,Shen L,Xu Y,Sun L
Sun Feb 01 00:00:00 EST 2015
Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.
Anatomical record (Hoboken, N.J. : 2007)
Yang X,Xiang X,Xia M,Su J,Wu Y,Shen L,Xu Y,Sun L
Sun Feb 01 00:00:00 EST 2015
Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Xie CW,Zhou Y,Liu SL,Fang ZY,Su B,Zhang W
Sun Nov 01 00:00:00 EDT 2015
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
PloS one
Qi K,Li L,Li X,Zhao J,Wang Y,You S,Hu F,Zhang H,Cheng Y,Kang S,Cui H,Duan L,Jin C,Zheng Q,Yang Y
Tue Mar 15 00:00:00 EDT 2016
Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
PloS one
Qi K,Li L,Li X,Zhao J,Wang Y,You S,Hu F,Zhang H,Cheng Y,Kang S,Cui H,Duan L,Jin C,Zheng Q,Yang Y
Tue Mar 15 00:00:00 EDT 2016
8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.
International journal of molecular sciences
Zhang C,Jiang Y,Zhang J,Huang J,Wang J
Thu Jul 02 00:00:00 EDT 2015
G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.
Leukemia & lymphoma
Zuo B,Li M,Liu Y,Li K,Ma S,Cui M,Qin Y,Zhu H,Pan X,Guo J,Dai Z,Yu W
Wed Jul 01 00:00:00 EDT 2015
IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Cellular signalling
Zheng C,Zheng Z,Zhang Z,Meng J,Liu Y,Ke X,Hu Q,Wang H
Tue Dec 01 00:00:00 EST 2015
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Drug design, development and therapy
Zhang L,Tian W,Kim S,Ding W,Tong Y,Chen S
Tue Mar 08 00:00:00 EST 2016
Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo.
Drug design, development and therapy
Zhang L,Tian W,Kim S,Ding W,Tong Y,Chen S
Tue Mar 08 00:00:00 EST 2016
Directional Plk1 inhibition-driven cell cycle interruption using amphiphilic thin-coated peptide-lanthanide upconversion nanomaterials as in vivo tumor suppressors.
Journal of materials chemistry. B
Chan CF,Lan R,Tsang MK,Zhou D,Lear S,Chan WL,Cobb SL,Wong WK,Hao J,Wong WT,Wong KL
Tue Apr 07 00:00:00 EDT 2015
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Proteomics
Hao L,Zhou X,Liu S,Sun M,Song Y,Du S,Sun B,Guo C,Gong L,Hu J,Guan H,Shao S
Tue Sep 01 00:00:00 EDT 2015
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Protein & cell
Wen P,Kong R,Liu J,Zhu L,Chen X,Li X,Nie Y,Wu K,Wu JY
Mon Sep 01 00:00:00 EDT 2014
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Protein & cell
Wen P,Kong R,Liu J,Zhu L,Chen X,Li X,Nie Y,Wu K,Wu JY
Mon Sep 01 00:00:00 EDT 2014
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Thrombosis research
Xu Y,Kong X,Zhou H,Zhang X,Liu J,Yan J,Xie H,Xie Y
Fri Aug 01 00:00:00 EDT 2014
oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway.
Thrombosis research
Xu Y,Kong X,Zhou H,Zhang X,Liu J,Yan J,Xie H,Xie Y
Fri Aug 01 00:00:00 EDT 2014
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
EMBO reports
Lv X,Jiang H,Liu Y,Lei X,Jiao J
Mon Dec 01 00:00:00 EST 2014
MicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.
EMBO reports
Lv X,Jiang H,Liu Y,Lei X,Jiao J
Mon Dec 01 00:00:00 EST 2014
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
International journal of cancer
Nelson M,Millican-Slater R,Forrest LC,Brackenbury WJ
Sat Nov 15 00:00:00 EST 2014
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
International journal of cancer
Nelson M,Millican-Slater R,Forrest LC,Brackenbury WJ
Sat Nov 15 00:00:00 EST 2014
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis.
International journal of cancer
Nelson M,Millican-Slater R,Forrest LC,Brackenbury WJ
Sat Nov 15 00:00:00 EST 2014
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
European journal of medicinal chemistry
Yu Q,Liu Y,Xu L,Zheng C,Le F,Qin X,Liu Y,Liu J
Wed Jul 23 00:00:00 EDT 2014
Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.
European journal of medicinal chemistry
Yu Q,Liu Y,Xu L,Zheng C,Le F,Qin X,Liu Y,Liu J
Wed Jul 23 00:00:00 EDT 2014
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Yang F,Wang Z,Wei X,Han H,Meng X,Zhang Y,Shi W,Li F,Xin T,Pang Q,Yi F
Tue Apr 01 00:00:00 EDT 2014
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Gong N,Xiao Q,Zhu B,Zhang CY,Wang YC,Fan H,Ma AN,Wang YX
Wed Apr 09 00:00:00 EDT 2014
Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Gong N,Xiao Q,Zhu B,Zhang CY,Wang YC,Fan H,Ma AN,Wang YX
Wed Apr 09 00:00:00 EDT 2014
Ezh2 regulates adult hippocampal neurogenesis and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhang J,Ji F,Liu Y,Lei X,Li H,Ji G,Yuan Z,Jiao J
Wed Apr 09 00:00:00 EDT 2014
Ezh2 regulates adult hippocampal neurogenesis and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhang J,Ji F,Liu Y,Lei X,Li H,Ji G,Yuan Z,Jiao J
Wed Apr 09 00:00:00 EDT 2014
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Journal of molecular biology
Chen M,Liu T,Xu L,Gao X,Liu X,Wang C,He Q,Zhang G,Liu L
Tue Sep 09 00:00:00 EDT 2014
Direct interaction of 14-3-3ζ with ezrin promotes cell migration by regulating the formation of membrane ruffle.
Journal of molecular biology
Chen M,Liu T,Xu L,Gao X,Liu X,Wang C,He Q,Zhang G,Liu L
Tue Sep 09 00:00:00 EDT 2014
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Chinese medical journal
Li N,Zhang Q,Qian H,Jin C,Yang Y,Gao R
Mon Feb 02 00:00:00 EST 2015
Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Chinese medical journal
Li N,Zhang Q,Qian H,Jin C,Yang Y,Gao R
Mon Feb 02 00:00:00 EST 2015
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Neural regeneration research
Yin F,Meng C,Lu R,Li L,Zhang Y,Chen H,Qin Y,Guo L
Mon Sep 15 00:00:00 EDT 2014
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Neural regeneration research
Yin F,Meng C,Lu R,Li L,Zhang Y,Chen H,Qin Y,Guo L
Mon Sep 15 00:00:00 EDT 2014
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
International journal of oncology
Chen MJ,Gao XJ,Xu LN,Liu TF,Liu XH,Liu LX
Wed Oct 01 00:00:00 EDT 2014
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells.
International journal of oncology
Chen MJ,Gao XJ,Xu LN,Liu TF,Liu XH,Liu LX
Wed Oct 01 00:00:00 EDT 2014
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Shi J,Sun J,Wang B,Wu M,Zhang J,Duan Z,Wang H,Hu N,Hu Y
Wed Oct 01 00:00:00 EDT 2014
Novel microRNA-like viral small regulatory RNAs arising during human hepatitis A virus infection.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Shi J,Sun J,Wang B,Wu M,Zhang J,Duan Z,Wang H,Hu N,Hu Y
Wed Oct 01 00:00:00 EDT 2014
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Journal of molecular and cellular cardiology
Zhang Y,Yang X,Bian F,Wu P,Xing S,Xu G,Li W,Chi J,Ouyang C,Zheng T,Wu D,Zhang Y,Li Y,Jin S
Tue Jul 01 00:00:00 EDT 2014
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Journal of molecular and cellular cardiology
Zhang Y,Yang X,Bian F,Wu P,Xing S,Xu G,Li W,Chi J,Ouyang C,Zheng T,Wu D,Zhang Y,Li Y,Jin S
Tue Jul 01 00:00:00 EDT 2014
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
International immunopharmacology
Zeng L,Wang W,Rong XF,Zhong Y,Jia P,Zhou GQ,Li RH
Wed Jan 01 00:00:00 EST 2014
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
International immunopharmacology
Zeng L,Wang W,Rong XF,Zhong Y,Jia P,Zhou GQ,Li RH
Wed Jan 01 00:00:00 EST 2014
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Apoptosis : an international journal on programmed cell death
Yang SD,Ma L,Gu TX,Ding WY,Zhang F,Shen Y,Zhang YZ,Yang DL,Zhang D,Sun YP,Song YL
Thu May 01 00:00:00 EDT 2014
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Apoptosis : an international journal on programmed cell death
Yang SD,Ma L,Gu TX,Ding WY,Zhang F,Shen Y,Zhang YZ,Yang DL,Zhang D,Sun YP,Song YL
Thu May 01 00:00:00 EDT 2014
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
Apoptosis : an international journal on programmed cell death
Zheng X,Li D,Zhao C,Wang Q,Song H,Qin Y,Liao L,Zhang L,Lin Y,Wang X
Fri Aug 01 00:00:00 EDT 2014
Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative.
Apoptosis : an international journal on programmed cell death
Zheng X,Li D,Zhao C,Wang Q,Song H,Qin Y,Liao L,Zhang L,Lin Y,Wang X
Fri Aug 01 00:00:00 EDT 2014
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
Journal of endocrinological investigation
Jiang P,Zhang L,Zhu W,Li H,Dang R,Tang M
Sat Nov 01 00:00:00 EDT 2014
Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.
Journal of endocrinological investigation
Jiang P,Zhang L,Zhu W,Li H,Dang R,Tang M
Sat Nov 01 00:00:00 EDT 2014
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Nanoscale research letters
Zhang M,Yang J,Shu J,Fu C,Liu S,Xu G,Zhang D
Fri Nov 21 00:00:00 EST 2014
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Nanoscale research letters
Zhang M,Yang J,Shu J,Fu C,Liu S,Xu G,Zhang D
Fri Nov 21 00:00:00 EST 2014
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
World journal of gastroenterology
Yu WD,Peng YF,Pan HD,Wang L,Li K,Gu J
Fri Nov 21 00:00:00 EST 2014
Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma.
World journal of gastroenterology
Yu WD,Peng YF,Pan HD,Wang L,Li K,Gu J
Fri Nov 21 00:00:00 EST 2014
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
International journal of molecular medicine
Zhang CY,Bao W,Wang LH
Sun Jun 01 00:00:00 EDT 2014
Downregulation of p16(ink4a) inhibits cell proliferation and induces G1 cell cycle arrest in cervical cancer cells.
International journal of molecular medicine
Zhang CY,Bao W,Wang LH
Sun Jun 01 00:00:00 EDT 2014
Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells.
International journal of molecular medicine
Wang T,Zhou H,Xie H,Mu Y,Xu Y,Liu J,Zhang X
Tue Apr 01 00:00:00 EDT 2014
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Neuropharmacology
Gong N,Fan H,Ma AN,Xiao Q,Wang YX
Mon Sep 01 00:00:00 EDT 2014
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors.
Neuropharmacology
Gong N,Fan H,Ma AN,Xiao Q,Wang YX
Mon Sep 01 00:00:00 EDT 2014
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
The Journal of general virology
Yang X,Ouyang H,Chen F,Pang D,Dong M,Yang S,Liu X,Peng Z,Wang F,Zhang X,Ren L
Sun Jun 01 00:00:00 EDT 2014
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death.
The Journal of general virology
Yang X,Ouyang H,Chen F,Pang D,Dong M,Yang S,Liu X,Peng Z,Wang F,Zhang X,Ren L
Sun Jun 01 00:00:00 EDT 2014
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
Human molecular genetics
Jia S,Muto A,Orisme W,Henson HE,Parupalli C,Ju B,Baier H,Taylor MR
Sun Jun 01 00:00:00 EDT 2014
Zebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formation.
Human molecular genetics
Jia S,Muto A,Orisme W,Henson HE,Parupalli C,Ju B,Baier H,Taylor MR
Sun Jun 01 00:00:00 EDT 2014
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Toxicology
Fan H,Cai Y,Xie P,Xiao W,Chen J,Ji W,Zhao S
Wed May 07 00:00:00 EDT 2014
Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells.
Toxicology
Fan H,Cai Y,Xie P,Xiao W,Chen J,Ji W,Zhao S
Wed May 07 00:00:00 EDT 2014
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
Journal of the neurological sciences
Yu DS,Cao Y,Mei XF,Wang YF,Fan ZK,Wang YS,Lv G
Sat Nov 15 00:00:00 EST 2014
Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats.
Journal of the neurological sciences
Yu DS,Cao Y,Mei XF,Wang YF,Fan ZK,Wang YS,Lv G
Sat Nov 15 00:00:00 EST 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
Psychopharmacology
Jiang P,Xue Y,Li HD,Liu YP,Cai HL,Tang MM,Zhang LH
Mon Sep 01 00:00:00 EDT 2014
Dysregulation of vitamin D metabolism in the brain and myocardium of rats following prolonged exposure to dexamethasone.
Psychopharmacology
Jiang P,Xue Y,Li HD,Liu YP,Cai HL,Tang MM,Zhang LH
Mon Sep 01 00:00:00 EDT 2014
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Journal of atherosclerosis and thrombosis
Zhang X,Xie Y,Zhou H,Xu Y,Liu J,Xie H,Yan J
Thu Jul 16 00:00:00 EDT 2015
Involvement of TLR4 in oxidized LDL/β2GPI/anti-β2GPI-induced transformation of macrophages to foam cells.
Journal of atherosclerosis and thrombosis
Zhang X,Xie Y,Zhou H,Xu Y,Liu J,Xie H,Yan J
Thu Jul 16 00:00:00 EDT 2015
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Cellular and molecular neurobiology
Zhao H,Zhao W,Lok K,Wang Z,Yin M
Tue Apr 01 00:00:00 EDT 2014
A synergic role of caspase-6 and caspase-3 in Tau truncation at D421 induced by H2O 2.
Cellular and molecular neurobiology
Zhao H,Zhao W,Lok K,Wang Z,Yin M
Tue Apr 01 00:00:00 EDT 2014
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Oncology reports
Liu Y,Wu C,Wang Y,Wen S,Wang J,Chen Z,He Q,Feng D
Sat Nov 01 00:00:00 EDT 2014
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
Biological trace element research
Duan XQ,Zhao ZT,Zhang XY,Wang Y,Wang H,Liu DW,Li GS,Jing L
Mon Dec 01 00:00:00 EST 2014
Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.
Biological trace element research
Duan XQ,Zhao ZT,Zhang XY,Wang Y,Wang H,Liu DW,Li GS,Jing L
Mon Dec 01 00:00:00 EST 2014
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Nanotechnology
Li Y,Wang S,Wang Z,Qian X,Fan J,Zeng X,Sun Y,Song P,Feng M,Ju D
Fri Sep 12 00:00:00 EDT 2014
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells.
Nanotechnology
Li Y,Wang S,Wang Z,Qian X,Fan J,Zeng X,Sun Y,Song P,Feng M,Ju D
Fri Sep 12 00:00:00 EDT 2014
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Pharmacology, biochemistry, and behavior
Jin W,Jia Y,Huang L,Wang T,Wang H,Dong Y,Zhang H,Fan M,Lv P
Mon Sep 01 00:00:00 EDT 2014
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats.
Pharmacology, biochemistry, and behavior
Jin W,Jia Y,Huang L,Wang T,Wang H,Dong Y,Zhang H,Fan M,Lv P
Mon Sep 01 00:00:00 EDT 2014
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
Clinics and research in hepatology and gastroenterology
Xiang J,Luo F,Chen Y,Zhu F,Wang J
Tue Apr 01 00:00:00 EDT 2014
si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma.
Clinics and research in hepatology and gastroenterology
Xiang J,Luo F,Chen Y,Zhu F,Wang J
Tue Apr 01 00:00:00 EDT 2014
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
Oncology letters
Liu Q,Zhang C,Ma G,Zhang Q
Sat Feb 01 00:00:00 EST 2014
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme.
Oncology letters
Liu Q,Zhang C,Ma G,Zhang Q
Sat Feb 01 00:00:00 EST 2014
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Asian journal of andrology
Pereira CD,Severo M,Rafael L,Martins MJ,Neves D
Fri Aug 21 00:00:00 EDT 2015
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Asian journal of andrology
Pereira CD,Severo M,Rafael L,Martins MJ,Neves D
Fri Aug 21 00:00:00 EDT 2015
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Scandinavian journal of gastroenterology
Wang F,Bu G,Feng Q,Liu Z,Xu C,Shen S,Yuan Y
Fri Aug 01 00:00:00 EDT 2014
The expression level of TRAF1 in human gastric mucosa is related to virulence genotypes of Helicobacter pylori.
Scandinavian journal of gastroenterology
Wang F,Bu G,Feng Q,Liu Z,Xu C,Shen S,Yuan Y
Fri Aug 01 00:00:00 EDT 2014
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
Experimental and therapeutic medicine
Zhang W,Hu J,Ma Q,Hu S,Wang Y,Wen X,Ma Y,Xu H,Qian H,Xu W
Mon Sep 01 00:00:00 EDT 2014
Cryopreserved mouse fetal liver stromal cells treated with mitomycin C are able to support the growth of human embryonic stem cells.
Experimental and therapeutic medicine
Zhang W,Hu J,Ma Q,Hu S,Wang Y,Wen X,Ma Y,Xu H,Qian H,Xu W
Mon Sep 01 00:00:00 EDT 2014
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Molecular biology reports
Awan MU,Hasan M,Iqbal J,Lei R,Lee WF,Hong M,Qing H,Deng Y
Mon Sep 01 00:00:00 EDT 2014
Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells.
Molecular biology reports
Awan MU,Hasan M,Iqbal J,Lei R,Lee WF,Hong M,Qing H,Deng Y
Mon Sep 01 00:00:00 EDT 2014
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Pharmacogenomics
Wang H,Bian T,Jin T,Chen Y,Lin A,Chen C
Tue Apr 01 00:00:00 EDT 2014
Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
Pharmacogenomics
Wang H,Bian T,Jin T,Chen Y,Lin A,Chen C
Tue Apr 01 00:00:00 EDT 2014
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Scientific reports
Lv X,Jiang H,Li B,Liang Q,Wang S,Zhao Q,Jiao J
Mon Aug 11 00:00:00 EDT 2014
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Scientific reports
Lv X,Jiang H,Li B,Liang Q,Wang S,Zhao Q,Jiao J
Mon Aug 11 00:00:00 EDT 2014
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
PloS one
Xu Q,Xia P,Li X,Wang W,Liu Z,Gao X
Mon Sep 29 00:00:00 EDT 2014
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
PloS one
Xu Q,Xia P,Li X,Wang W,Liu Z,Gao X
Mon Sep 29 00:00:00 EDT 2014
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
PloS one
Xu Q,Xia P,Li X,Wang W,Liu Z,Gao X
Mon Sep 29 00:00:00 EDT 2014
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Nature communications
Orosco LA,Ross AP,Cates SL,Scott SE,Wu D,Sohn J,Pleasure D,Pleasure SJ,Adamopoulos IE,Zarbalis KS
Mon Sep 08 00:00:00 EDT 2014
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Nature communications
Orosco LA,Ross AP,Cates SL,Scott SE,Wu D,Sohn J,Pleasure D,Pleasure SJ,Adamopoulos IE,Zarbalis KS
Mon Sep 08 00:00:00 EDT 2014
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
PloS one
Ma FJ,Liu ZB,Hu X,Ling H,Li S,Wu J,Shao ZM
Tue Dec 22 00:00:00 EST 2015
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients.
PloS one
Ma FJ,Liu ZB,Hu X,Ling H,Li S,Wu J,Shao ZM
Tue Dec 22 00:00:00 EST 2015
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
International journal of clinical and experimental medicine
Zhao L,Teng B,Wen L,Feng Q,Wang H,Li N,Wang Y,Liang Z
Thu Mar 06 00:00:00 EST 2014
mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.
International journal of clinical and experimental medicine
Zhao L,Teng B,Wen L,Feng Q,Wang H,Li N,Wang Y,Liang Z
Thu Mar 06 00:00:00 EST 2014
The association of HMGB1 gene with the prognosis of HCC.
PloS one
Xiao J,Ding Y,Huang J,Li Q,Liu Y,Ni W,Zhang Y,Zhu Y,Chen L,Chen B
Sat Jan 10 00:00:00 EST 2015
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
PloS one
Zuo X,Pan W,Feng T,Shi X,Dai J
Wed Sep 10 00:00:00 EDT 2014
Matrix metalloproteinase 3 promotes cellular anti-dengue virus response via interaction with transcription factor NFκB in cell nucleus.
PloS one
Zuo X,Pan W,Feng T,Shi X,Dai J
Wed Sep 10 00:00:00 EDT 2014
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
International journal of clinical and experimental pathology
Jiang SH,He P,Ma MZ,Wang Y,Li RK,Fang F,Fu Y,Tian GA,Qin WX,Zhang ZG
Thu May 14 00:00:00 EDT 2015
PNMA1 promotes cell growth in human pancreatic ductal adenocarcinoma.
International journal of clinical and experimental pathology
Jiang SH,He P,Ma MZ,Wang Y,Li RK,Fang F,Fu Y,Tian GA,Qin WX,Zhang ZG
Thu May 14 00:00:00 EDT 2015
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Journal of neuroinflammation
Wang Y,Ge P,Yang L,Wu C,Zha H,Luo T,Zhu Y
Fri Jan 24 00:00:00 EST 2014
Protection of ischemic post conditioning against transient focal ischemia-induced brain damage is associated with inhibition of neuroinflammation via modulation of TLR2 and TLR4 pathways.
Journal of neuroinflammation
Wang Y,Ge P,Yang L,Wu C,Zha H,Luo T,Zhu Y
Fri Jan 24 00:00:00 EST 2014
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.
Cell death & disease
Wang Z,Shi X,Li Y,Fan J,Zeng X,Xian Z,Wang Z,Sun Y,Wang S,Song P,Zhao S,Hu H,Ju D
Thu Dec 11 00:00:00 EST 2014
Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx.
Scientific reports
Zhang Y,Guo X,Guo J,He Q,Li H,Song Y,Zhang H
Fri Jul 18 00:00:00 EDT 2014
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
International journal of molecular sciences
Liang Z,Yi Y,Guo Y,Wang R,Hu Q,Xiong X
Thu May 22 00:00:00 EDT 2014
Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum.
International journal of molecular sciences
Liang Z,Yi Y,Guo Y,Wang R,Hu Q,Xiong X
Thu May 22 00:00:00 EDT 2014
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
PloS one
Chu W,Song X,Yang X,Ma L,Zhu J,He M,Wang Z,Wu Y
Tue Dec 01 00:00:00 EST 2015
Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.
PloS one
Chu W,Song X,Yang X,Ma L,Zhu J,He M,Wang Z,Wu Y
Tue Dec 01 00:00:00 EST 2015
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
International journal of molecular sciences
Wu X,Deng G,Hao X,Li Y,Zeng J,Ma C,He Y,Liu X,Wang Y
Fri Mar 21 00:00:00 EDT 2014
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
International journal of molecular sciences
Wu X,Deng G,Hao X,Li Y,Zeng J,Ma C,He Y,Liu X,Wang Y
Fri Mar 21 00:00:00 EDT 2014
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zhang T,Sun Q,Liu T,Chen J,Du S,Ren C,Liao G,Yuan Y
Mon Dec 01 00:00:00 EST 2014
MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zhang T,Sun Q,Liu T,Chen J,Du S,Ren C,Liao G,Yuan Y
Mon Dec 01 00:00:00 EST 2014
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Chang BP,Wang DS,Xing JW,Yang SH,Chu Q,Yu SY
Tue Apr 01 00:00:00 EDT 2014
miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Chang BP,Wang DS,Xing JW,Yang SH,Chu Q,Yu SY
Tue Apr 01 00:00:00 EDT 2014
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
World journal of surgical oncology
Su Z,Yin J,Zhao L,Li R,Liang H,Zhang J,Wang K
Tue Dec 02 00:00:00 EST 2014
Lentiviral vector-mediated RBM5 overexpression downregulates EGFR expression in human non-small cell lung cancer cells.
World journal of surgical oncology
Su Z,Yin J,Zhao L,Li R,Liang H,Zhang J,Wang K
Tue Dec 02 00:00:00 EST 2014
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
Scientific reports
Li L,Wang L,Wu Z,Yao L,Wu Y,Huang L,Liu K,Zhou X,Gou D
Fri Aug 29 00:00:00 EDT 2014
Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis.
Scientific reports
Li L,Wang L,Wu Z,Yao L,Wu Y,Huang L,Liu K,Zhou X,Gou D
Fri Aug 29 00:00:00 EDT 2014
In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide.
Archives of virology
Liu J,Zhou Z,Li K,Han M,Yang J,Wang S
Mon Sep 01 00:00:00 EDT 2014
A central role for TRPS1 in the control of cell cycle and cancer development.
Oncotarget
Wu L,Wang Y,Liu Y,Yu S,Xie H,Shi X,Qin S,Ma F,Tan TZ,Thiery JP,Chen L
Mon Sep 15 00:00:00 EDT 2014
A central role for TRPS1 in the control of cell cycle and cancer development.
Oncotarget
Wu L,Wang Y,Liu Y,Yu S,Xie H,Shi X,Qin S,Ma F,Tan TZ,Thiery JP,Chen L
Mon Sep 15 00:00:00 EDT 2014
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Journal of translational medicine
Xiang J,Fang L,Luo Y,Yang Z,Liao Y,Cui J,Huang M,Yang Z,Huang Y,Fan X,Wang H,Wang L,Peng J,Wang J
Wed Nov 19 00:00:00 EST 2014
Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer.
Journal of translational medicine
Xiang J,Fang L,Luo Y,Yang Z,Liao Y,Cui J,Huang M,Yang Z,Huang Y,Fan X,Wang H,Wang L,Peng J,Wang J
Wed Nov 19 00:00:00 EST 2014
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Nature communications
Muratani M,Deng N,Ooi WF,Lin SJ,Xing M,Xu C,Qamra A,Tay ST,Malik S,Wu J,Lee MH,Zhang S,Tan LL,Chua H,Wong WK,Ong HS,Ooi LL,Chow PK,Chan WH,Soo KC,Goh LK,Rozen S,Teh BT,Yu Q,Ng HH,Tan P
Thu Jul 10 00:00:00 EDT 2014
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Nature communications
Muratani M,Deng N,Ooi WF,Lin SJ,Xing M,Xu C,Qamra A,Tay ST,Malik S,Wu J,Lee MH,Zhang S,Tan LL,Chua H,Wong WK,Ong HS,Ooi LL,Chow PK,Chan WH,Soo KC,Goh LK,Rozen S,Teh BT,Yu Q,Ng HH,Tan P
Thu Jul 10 00:00:00 EDT 2014
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
PloS one
Liu B,Che Q,Qiu H,Bao W,Chen X,Lu W,Li B,Wan X
Wed Oct 15 00:00:00 EDT 2014
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
PloS one
Liu B,Che Q,Qiu H,Bao W,Chen X,Lu W,Li B,Wan X
Wed Oct 15 00:00:00 EDT 2014
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Asian Pacific journal of cancer prevention : APJCP
Liang Z,Guo YT,Yi YJ,Wang RC,Hu QL,Xiong XY
Thu Mar 31 00:00:00 EDT 2016
Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
Asian Pacific journal of cancer prevention : APJCP
Liang Z,Guo YT,Yi YJ,Wang RC,Hu QL,Xiong XY
Thu Mar 31 00:00:00 EDT 2016
Toxic effects of levofloxacin on rat annulus fibrosus cells: an in-vitro study.
Medical science monitor : international medical journal of experimental and clinical research
Bai ZL,Chen Q,Yang SD,Zhang F,Wang HY,Yang DL,Ding WY
Sat Nov 08 00:00:00 EST 2014
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
PloS one
Lihong H,Linlin G,Yiping G,Yang S,Xiaoyu Q,Zhuzhu G,Xiaohan Y,Xin Z,Liyan X,Shujuan S
Mon Jun 01 00:00:00 EDT 2015
Proteomics approaches for identification of tumor relevant protein targets in pulmonary squamous cell carcinoma by 2D-DIGE-MS.
PloS one
Lihong H,Linlin G,Yiping G,Yang S,Xiaoyu Q,Zhuzhu G,Xiaohan Y,Xin Z,Liyan X,Shujuan S
Mon Jun 01 00:00:00 EDT 2015
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Scientific reports
Wang G,Ji Y,Li Z,Han X,Guo N,Song Q,Quan L,Wang T,Han W,Pang D,Ouyang H,Tang X
Fri May 09 00:00:00 EDT 2014
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Scientific reports
Wang G,Ji Y,Li Z,Han X,Guo N,Song Q,Quan L,Wang T,Han W,Pang D,Ouyang H,Tang X
Fri May 09 00:00:00 EDT 2014
Cholesterol-conjugated let-7a mimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy.
BMC cancer
Liu YM,Xia Y,Dai W,Han HY,Dong YX,Cai J,Zeng X,Luo FY,Yang T,Li YZ,Chen J,Guan J
Fri Nov 28 00:00:00 EST 2014
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
PloS one
Wang J,Ni Z,Duan Z,Wang G,Li F
Mon May 11 00:00:00 EDT 2015
Altered expression of hypoxia-inducible factor-1α (HIF-1α) and its regulatory genes in gastric cancer tissues.
PloS one
Wang J,Ni Z,Duan Z,Wang G,Li F
Mon May 11 00:00:00 EDT 2015
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Thrombosis research
Zhou H,Sheng L,Wang H,Xie H,Mu Y,Wang T,Yan J
Tue Sep 09 00:00:00 EDT 2014
Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways.
Thrombosis research
Zhou H,Sheng L,Wang H,Xie H,Mu Y,Wang T,Yan J
Tue Sep 09 00:00:00 EDT 2014
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Cancer science
Chen YF,Dong Z,Xia Y,Tang J,Peng L,Wang S,Lai D
Sun Dec 01 00:00:00 EST 2013
Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Cancer science
Chen YF,Dong Z,Xia Y,Tang J,Peng L,Wang S,Lai D
Sun Dec 01 00:00:00 EST 2013
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Neural regeneration research
Huai Y,Dong Y,Xu J,Meng N,Song C,Li W,Lv P
Fri Jul 05 00:00:00 EDT 2013
L-3-n-butylphthalide protects against vascular dementia via activation of the Akt kinase pathway.
Neural regeneration research
Huai Y,Dong Y,Xu J,Meng N,Song C,Li W,Lv P
Fri Jul 05 00:00:00 EDT 2013
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Mediators of inflammation
Chen X,Shi X,Zhang X,Lei H,Long S,Su H,Pei Z,Huang R
Thu Jun 05 00:00:00 EDT 2014
Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B.
Mediators of inflammation
Chen X,Shi X,Zhang X,Lei H,Long S,Su H,Pei Z,Huang R
Thu Jun 05 00:00:00 EDT 2014
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Cell biology international
Gao X,Wang JY,Gao LM,Yin XF,Liu L
Thu Aug 01 00:00:00 EDT 2013
Identification and analysis of glycogen synthase kinase 3 beta1 interactome.
Cell biology international
Gao X,Wang JY,Gao LM,Yin XF,Liu L
Thu Aug 01 00:00:00 EDT 2013
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Molecular biology of the cell
Wang ZB,Jiang ZZ,Zhang QH,Hu MW,Huang L,Ou XH,Guo L,Ouyang YC,Hou Y,Brakebusch C,Schatten H,Sun QY
Sun Dec 01 00:00:00 EST 2013
Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.
Molecular biology of the cell
Wang ZB,Jiang ZZ,Zhang QH,Hu MW,Huang L,Ou XH,Guo L,Ouyang YC,Hou Y,Brakebusch C,Schatten H,Sun QY
Sun Dec 01 00:00:00 EST 2013
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
PloS one
Tian Y,Ding W,Wang Y,Ji T,Sun S,Mo Q,Chen P,Fang Y,Liu J,Wang B,Zhou J,Ma D,Wu P
Mon Oct 13 00:00:00 EDT 2014
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
PloS one
Tian Y,Ding W,Wang Y,Ji T,Sun S,Mo Q,Chen P,Fang Y,Liu J,Wang B,Zhou J,Ma D,Wu P
Mon Oct 13 00:00:00 EDT 2014
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
Cell death & disease
Li X,Li Z,Zhou W,Xing X,Huang L,Tian L,Chen J,Chen C,Ma X,Yang Z
Thu Sep 12 00:00:00 EDT 2013
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Journal of ethnopharmacology
Yang J,Wang HX,Zhang YJ,Yang YH,Lu ML,Zhang J,Li ST,Zhang SP,Li G
Thu Dec 12 00:00:00 EST 2013
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li X,Li F,Chu Y,Wang X,Zhang H,Hu Y,Zhang Y,Wang Z,Wei X,Jian W,Zhang X,Yi F
Fri Aug 29 00:00:00 EDT 2014
NOD2 deficiency protects against cardiac remodeling after myocardial infarction in mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li X,Li F,Chu Y,Wang X,Zhang H,Hu Y,Zhang Y,Wang Z,Wei X,Jian W,Zhang X,Yi F
Fri Aug 29 00:00:00 EDT 2014
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
PloS one
Peng H,Luo P,Li Y,Wang C,Liu X,Ye Z,Li C,Lou T
Tue Aug 12 00:00:00 EDT 2014
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
PloS one
Peng H,Luo P,Li Y,Wang C,Liu X,Ye Z,Li C,Lou T
Tue Aug 12 00:00:00 EDT 2014
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
CNS neuroscience & therapeutics
He HJ,Wang Y,Le Y,Duan KM,Yan XB,Liao Q,Liao Y,Tong JB,Terrando N,Ouyang W
Sat Dec 01 00:00:00 EST 2012
Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats.
CNS neuroscience & therapeutics
He HJ,Wang Y,Le Y,Duan KM,Yan XB,Liao Q,Liao Y,Tong JB,Terrando N,Ouyang W
Sat Dec 01 00:00:00 EST 2012
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Genes
Baguma-Nibasheka M,Macfarlane LA,Murphy PR
Thu Aug 16 00:00:00 EDT 2012
Regulation of fibroblast growth factor-2 expression and cell cycle progression by an endogenous antisense RNA.
Genes
Baguma-Nibasheka M,Macfarlane LA,Murphy PR
Thu Aug 16 00:00:00 EDT 2012
Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
Anti-cancer drugs
Sun H,Zheng X,Wang Q,Yan J,Li D,Zhou Y,Lin Y,Zhang L,Wang X
Thu Nov 01 00:00:00 EDT 2012
Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.
Amino acids
Sun M,Zhao Y,Gu Y,Xu C
Tue May 01 00:00:00 EDT 2012
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Oncology reports
Wang ZM,Cui YH,Li W,Chen SY,Liu TS
Fri Apr 01 00:00:00 EDT 2011
Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.
Oncology reports
Wang ZM,Cui YH,Li W,Chen SY,Liu TS
Fri Apr 01 00:00:00 EDT 2011
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
International journal of cardiology
Dong Q,Yang Y,Song L,Qian H,Xu Z
Thu Dec 15 00:00:00 EST 2011
Atorvastatin prevents mesenchymal stem cells from hypoxia and serum-free injury through activating AMP-activated protein kinase.
International journal of cardiology
Dong Q,Yang Y,Song L,Qian H,Xu Z
Thu Dec 15 00:00:00 EST 2011
Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts.
Circulation journal : official journal of the Japanese Circulation Society
Xu H,Yang YJ,Qian HY,Tang YD,Wang H,Zhang Q
Fri Sep 16 00:00:00 EDT 2011
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.
Thrombosis and haemostasis
Xu G,Wen H,Zhou H,Guo D,Zhou F,Chen D,Xie H,Wang T,Wang H
Thu Dec 01 00:00:00 EST 2011
Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation.
Cell cycle (Georgetown, Tex.)
Sun SC,Wei L,Li M,Lin SL,Xu BZ,Liang XW,Kim NH,Schatten H,Lu SS,Sun QY
Thu Oct 15 00:00:00 EDT 2009
[Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1.].
Zhongguo fei ai za zhi = Chinese journal of lung cancer
Jia G,Zhang W,Zhou J,Zhu Z
Fri Jun 20 00:00:00 EDT 2008
