Product References
Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis.
Gut microbes
Jin J,Xu Z,Zhang L,Zhang C,Zhao X,Mao Y,Zhang H,Liang X,Wu J,Yang Y,Zhang J
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Tue Jan 24 00:00:00 EST 2023
The effect of Abi3 locus deletion on the progression of Alzheimer's disease-related pathologies.
Frontiers in immunology
Karahan H,Smith DC,Kim B,McCord B,Mantor J,John SK,Al-Amin MM,Dabin LC,Kim J
51-2700 was used in Western Blotting to suggest that loss of ABI3 function may exacerbate AD progression by increasing Aβ accumulation and inflammation starting from earlier stages of the pathology.
Fri Mar 17 00:00:00 EDT 2023
Modification of the Marmarou and Foda model of diffuse axonal injury (DAI) improves percentage survival of rats at 24 h and increases the amount of DAI identified.
Journal of forensic sciences
Fernández-Liste A,González-Cantalapiedra A,Cascallana JL,García-Caballero T,Gallego R
51-2700 was used in Immunohistochemistry to enhance rat survival and mimic traumatic diffuse axonal injury (DAI) in a manner more similar to human cases by implementing modifications such as using a wider head protector disc, elevating the rat's head during impact, and ensuring a soft foam bed.
Sat Jul 01 00:00:00 EDT 2023
A closed-body preclinical model to investigate blast-induced spinal cord injury.
Frontiers in molecular neuroscience
Norris C,Weatherbee J,Murphy S,Marquetti I,Maniakhina L,Boruch A,VandeVord P
51-2700 was used in Immunohistochemistry to indicate that pathophysiological responses from the blast alone are detectable, likely contributing to the combined effects.
Sun Jul 02 00:00:00 EDT 2023
Selective brain hypothermia attenuates focal cerebral ischemic injury and improves long-term neurological outcome in aged female mice.
CNS neuroscience & therapeutics
Liu L,Liu J,Li M,Lyu J,Su W,Feng S,Ji X
51-2700 was used in Immunohistochemistry-immunofluorescence to investigate the effects of mild selective brain hypothermia on aged female ischemic mice.
Sun Jan 01 00:00:00 EST 2023
Repurposing Diltiazem for Its Neuroprotective Anti-Dementia Role against Intra-Cerebroventricular Streptozotocin-Induced Sporadic Alzheimer's Disease-Type Rat Model.
Life (Basel, Switzerland)
Alluri R,Kilari EK,Pasala PK,Kopalli SR,Koppula S
51-2700 was used in Western Blotting to invesitgate the neuroprotective anti-dementia effects of DTZ against intra-cerebroventricular-streptozotocin (ICV-STZ)-induced sporadic AD (SAD)-type rat model.
Fri Aug 04 00:00:00 EDT 2023
The Central Fluid Percussion Brain Injury in a Gyrencephalic Pig Brain: Scalable Diffuse Injury and Tissue Viability for Glial Cell Immunolabeling following Long-Term Refrigerated Storage.
Biomedicines
Pavlichenko M,Lafrenaye AD
51-2700 was used in Immunohistochemistry to indicate that a micro pig CFPI model could allow for specific investigations of various degrees of diffuse pathological burdens following TBI.
Sat Jun 10 00:00:00 EDT 2023
Effects of experimental glaucoma in Lama1nmf223 mutant mice.
Experimental eye research
Madhoun S,Martins MTC,Korneva A,Johnson TV,Kimball E,Quillen S,Pease ME,Edwards M,Quigley H
51-2700 was used in Immunohistochemistry-immunofluorescence to show that axonal transport blockade significantly differed between old B6 and old LM mice in control and glaucoma eyes, and younger LM mice had abnormal axon paths and lower optic nerve area.
Sun Jan 01 00:00:00 EST 2023
TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation.
Journal of neuroinflammation
Lin W,Li Z,Liang G,Zhou R,Zheng X,Tao R,Huo Q,Su C,Li M,Xu N,Tang C,Song JX
51-2700 was used in Western Blotting to suggest that TNEA attenuates AD-associated memory impairment via promoting TFEB/TFE3-mediated autophagic clearance of Aβ and NLRP3 inflammasome, and partially reveal the molecular basis of combined acupoints therapy originated from ancient wisdom.
Thu Feb 02 00:00:00 EST 2023
Blast-induced axonal degeneration in the rat cerebellum in the absence of head movement.
Scientific reports
Bishop R,Won SJ,Irvine KA,Basu J,Rome ES,Swanson RA
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Fri Jan 07 00:00:00 EST 2022
Blast-induced axonal degeneration in the rat cerebellum in the absence of head movement.
Scientific reports
Bishop R,Won SJ,Irvine KA,Basu J,Rome ES,Swanson RA
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Fri Jan 07 00:00:00 EST 2022
In Vivo Prenylomic Profiling in the Brain of a Transgenic Mouse Model of Alzheimer's Disease Reveals Increased Prenylation of a Key Set of Proteins.
ACS chemical biology
Jeong A,Auger SA,Maity S,Fredriksen K,Zhong R,Li L,Distefano MD
51-2700 was used in Western Blotting to highlight the power of in vivo metabolic labeling approach to identify multiple post-translationally modified proteins that may serve as potential therapeutic targets for a disease that has proved refractory to treatment thus far.
Fri Oct 21 00:00:00 EDT 2022
Cyclin-dependent kinase 7 contributes to myelin maintenance in the adult central nervous system and promotes myelin gene expression.
Glia
Dion V,Schumacher N,Masar N,Pieltain A,Tocquin P,Lesoinne P,Malgrange B,Vandenbosch R,Franzen R
51-2700 was used in Western Blotting to demonstrate that inhibiton of Cdk7 leads to an altered myelination-associated morphological modification combined with decreased expression of myelin-specific genes.
Thu Sep 01 00:00:00 EDT 2022
Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.
Nature biomedical engineering
Xie C,Zhuang XX,Niu Z,Ai R,Lautrup S,Zheng S,Jiang Y,Han R,Gupta TS,Cao S,Lagartos-Donate MJ,Cai CZ,Xie LM,Caponio D,Wang WW,Schmauck-Medina T,Zhang J,Wang HL,Lou G,Xiao X,Zheng W,Palikaras K,Yang G,Caldwell KA,Caldwell GA,Shen HM,Nilsen H,Lu JH,Fang EF
51-2700 was used in Western Blot to report the combined use of unsupervised machine learning and a cross-species approach for the screening and experimental validation of new mitophagy-inducing compounds.
Sat Jan 01 00:00:00 EST 2022
Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.
Nature biomedical engineering
Xie C,Zhuang XX,Niu Z,Ai R,Lautrup S,Zheng S,Jiang Y,Han R,Gupta TS,Cao S,Lagartos-Donate MJ,Cai CZ,Xie LM,Caponio D,Wang WW,Schmauck-Medina T,Zhang J,Wang HL,Lou G,Xiao X,Zheng W,Palikaras K,Yang G,Caldwell KA,Caldwell GA,Shen HM,Nilsen H,Lu JH,Fang EF
51-2700 was used in Western Blot to report the combined use of unsupervised machine learning and a cross-species approach for the screening and experimental validation of new mitophagy-inducing compounds.
Sat Jan 01 00:00:00 EST 2022
Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord.
Cell reports
Khandker L,Jeffries MA,Chang YJ,Mather ML,Evangelou AV,Bourne JN,Tafreshi AK,Ornelas IM,Bozdagi-Gunal O,Macklin WB,Wood TL
51-2700 was used in Western Blot to examine cholesterol regulation in oligodendrocyte differentiation.
Tue Mar 01 00:00:00 EST 2022
Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice.
Nature communications
Chandana M,Anand A,Ghosh S,Das R,Beura S,Jena S,Suryawanshi AR,Padmanaban G,Nagaraj VA
51-2700 was used in Immunohistochemistry-immunofluorescence to show heme synthesized in asexual stages promotes cerebral pathogenesis by enhancing hemozoin formation.
Tue Jul 12 00:00:00 EDT 2022
STAT1 Contributes to Microglial/Macrophage Inflammation and Neurological Dysfunction in a Mouse Model of Traumatic Brain Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhao Y,Ma C,Chen C,Li S,Wang Y,Yang T,Stetler RA,Bennett MVL,Dixon CE,Chen J,Shi Y
51-2700 was used in Immunohistochemistry to show excellent efficacy of a selective STAT1 inhibitor fludarabine against TBI-induced functional deficits and brain injury using a mouse model, presenting STAT1 as a promising therapeutic target for TBI.
Wed Sep 28 00:00:00 EDT 2022
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.
Theranostics
Cai CZ,Zhuang XX,Zhu Q,Wu MY,Su H,Wang XJ,Iyaswamy A,Yue Z,Wang Q,Zhang B,Xue Y,Tan J,Li M,He H,Lu JH
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in ELISA
Thu Apr 21 00:00:00 EDT 2022
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.
Theranostics
Cai CZ,Zhuang XX,Zhu Q,Wu MY,Su H,Wang XJ,Iyaswamy A,Yue Z,Wang Q,Zhang B,Xue Y,Tan J,Li M,He H,Lu JH
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in ELISA
Thu Apr 21 00:00:00 EDT 2022
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation.
Autophagy
Cai CZ,Yang C,Zhuang XX,Yuan NN,Wu MY,Tan JQ,Song JX,Cheung KH,Su H,Wang YT,Tang BS,Behrends C,Durairajan SSK,Yue Z,Li M,Lu JH
51-2700 was used in ELISA to reveal a pivotal role of NRBF2 as a new RAB7 effector in modulating autophagosome maturation, providing insight into the molecular mechanism of NRBF2-PtdIns3K in regulating RAB7 activity for macroautophagy/autophagy maturation and Alzheimer disease-associated protein degradation.
Sat May 01 00:00:00 EDT 2021
Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).
Autophagy
Zheng X,Lin W,Jiang Y,Lu K,Wei W,Huo Q,Cui S,Yang X,Li M,Xu N,Tang C,Song JX
51-2700 was used in Immunohistochemistry to demonstrate the cognitive-enhancing effect of three-needle EA (TNEA) in an animal model of Alzheimer disease with beta-amyloid (Aβ) pathology (5xFAD).
Mon Nov 01 00:00:00 EDT 2021
Hyperoxygenation Treatment Reduces Beta-amyloid Deposition via MeCP2-dependent Upregulation of MMP-2 and MMP-9 in the Hippocampus of Tg-APP/PS1 Mice.
Experimental neurobiology
Choi J,Kwon H,Han PL
51-2700 was used in Western Blotting to suggest that hyperoxygenation increases the expression of MMP-2, MMP-9, and tPA, of which MMP-9 is upregulated via MeCP2 in neuronal cells, and MMP-2 and tPA are upregulated through MeCP2 and other nuclear factors.
Tue Aug 31 00:00:00 EDT 2021
Hyperoxygenation Treatment Reduces Beta-amyloid Deposition via MeCP2-dependent Upregulation of MMP-2 and MMP-9 in the Hippocampus of Tg-APP/PS1 Mice.
Experimental neurobiology
Choi J,Kwon H,Han PL
51-2700 was used in Western Blotting to suggest that hyperoxygenation increases the expression of MMP-2, MMP-9, and tPA, of which MMP-9 is upregulated via MeCP2 in neuronal cells, and MMP-2 and tPA are upregulated through MeCP2 and other nuclear factors.
Tue Aug 31 00:00:00 EDT 2021
Pentoxifylline prevents epileptic seizure via modulating HMGB1/RAGE/TLR4 signalling pathway and improves memory in pentylenetetrazol kindling rats.
Clinical and experimental pharmacology & physiology
Badawi GA,Shokr MM,Zaki HF,Mohamed AF
51-2700 was used in Western Blotting to find that PTX or its combination with phenytoin represent a promising drug to inhibit the epilepsy progression via targeting the HMGB1/TLR4/RAGE signalling pathway.
Sun Aug 01 00:00:00 EDT 2021
Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Acta neuropathologica communications
Jeong A,Cheng S,Zhong R,Bennett DA,Bergö MO,Li L
51-2700 was used in Western Blot to suggest that aberrant upregulation of protein farnesylation is an early driving force in the pathogenic cascade of AD and that targeting FT or its downstream signaling pathways presents a viable therapeutic strategy against AD.
Tue Jul 27 00:00:00 EDT 2021
Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Acta neuropathologica communications
Jeong A,Cheng S,Zhong R,Bennett DA,Bergö MO,Li L
51-2700 was used in Western Blot to suggest that aberrant upregulation of protein farnesylation is an early driving force in the pathogenic cascade of AD and that targeting FT or its downstream signaling pathways presents a viable therapeutic strategy against AD.
Tue Jul 27 00:00:00 EDT 2021
Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures.
Acta neuropathologica communications
Bradshaw DV,Knutsen AK,Korotcov A,Sullivan GM,Radomski KL,Dardzinski BJ,Zi X,McDaniel DP,Armstrong RC
51-2700 was used in Immunohistochemistry to evaluate Sarm1 deletion effects after TBI using a concussive model that causes traumatic axonal injury and progresses to CC atrophy at 10 weeks, indicating post-traumatic neurodegeneration.
Mon May 17 00:00:00 EDT 2021
Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures.
Acta neuropathologica communications
Bradshaw DV,Knutsen AK,Korotcov A,Sullivan GM,Radomski KL,Dardzinski BJ,Zi X,McDaniel DP,Armstrong RC
51-2700 was used in Immunohistochemistry to evaluate Sarm1 deletion effects after TBI using a concussive model that causes traumatic axonal injury and progresses to CC atrophy at 10 weeks, indicating post-traumatic neurodegeneration.
Mon May 17 00:00:00 EDT 2021
The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma.
PloS one
Kimball E,Schaub J,Quillen S,Keuthan C,Pease ME,Korneva A,Quigley H
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Mon Jul 19 00:00:00 EDT 2021
The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma.
PloS one
Kimball E,Schaub J,Quillen S,Keuthan C,Pease ME,Korneva A,Quigley H
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Mon Jul 19 00:00:00 EDT 2021
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
Scientific reports
Ryu J,Stone P,Lee S,Payne B,Gorse K,Lafrenaye A
51-2700 was used in Immunohistochemistry to suggest effects of Bup treatment on weight following CFPI and potential regional specificity of Bup-associated microglial and astrocyte alterations, but very little change in other acute pathology at 1-day post-injury.
Wed Apr 21 00:00:00 EDT 2021
Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury.
Scientific reports
Ryu J,Stone P,Lee S,Payne B,Gorse K,Lafrenaye A
51-2700 was used in Immunohistochemistry to suggest effects of Bup treatment on weight following CFPI and potential regional specificity of Bup-associated microglial and astrocyte alterations, but very little change in other acute pathology at 1-day post-injury.
Wed Apr 21 00:00:00 EDT 2021
Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging.
Aging
d'Uscio LV,Katusic ZS
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Thu Aug 12 00:00:00 EDT 2021
Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging.
Aging
d'Uscio LV,Katusic ZS
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Thu Aug 12 00:00:00 EDT 2021
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.
Acta neuropathologica communications
Kahriman A,Bouley J,Smith TW,Bosco DA,Woerman AL,Henninger N
51-2700 was used in Immunohistochemistry to compare the mouse closed-head traumatic brain injury model with human traumatic brain injury-associated tauopathy.
Tue Jun 29 00:00:00 EDT 2021
Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer's disease in a mouse model of Aβ amyloidosis.
Science advances
Karahan H,Smith DC,Kim B,Dabin LC,Al-Amin MM,Wijeratne HRS,Pennington T,Viana di Prisco G,McCord B,Lin PB,Li Y,Peng J,Oblak AL,Chu S,Atwood BK,Kim J
51-2700 was used in Western Blot to provide the first in vivo functional evidence that loss of ABI3 function may increase the risk of developing AD by affecting Aβ accumulation and neuroinflammation.
Fri Nov 05 00:00:00 EDT 2021
The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development.
Nature neuroscience
Cong Q,Soteros BM,Wollet M,Kim JH,Sia GM
51-2700 was used in Immunohistochemistry to study the roles of the sushi domain protein SRPX2, neurons express complement inhibitor, in complement-dependent synapse elimination.
Tue Sep 01 00:00:00 EDT 2020
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Aging cell
Song JX,Malampati S,Zeng Y,Durairajan SSK,Yang CB,Tong BC,Iyaswamy A,Shang WB,Sreenivasmurthy SG,Zhu Z,Cheung KH,Lu JH,Tang C,Xu N,Li M
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Sat Feb 01 00:00:00 EST 2020
Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig.
Frontiers in neurology
Lafrenaye A,Mondello S,Povlishock J,Gorse K,Walker S,Hayes R,Wang K,Kochanek PM
51-2700 was used in Immunohistochemistry to show that expression of the neurite outgrowth marker, growth-associated protein 43, was reduced in axonal swellings following LEV treatment.
Tue Feb 16 00:00:00 EST 2021
Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig.
Frontiers in neurology
Lafrenaye A,Mondello S,Povlishock J,Gorse K,Walker S,Hayes R,Wang K,Kochanek PM
51-2700 was used in Immunohistochemistry to show that expression of the neurite outgrowth marker, growth-associated protein 43, was reduced in axonal swellings following LEV treatment.
Tue Feb 16 00:00:00 EST 2021
Sex-Specific Differences in Rodents Following a Single Primary Blast Exposure: Focus on the Monoamine and Galanin Systems.
Frontiers in neurology
Kawa L,Arborelius UP,Hökfelt T,Risling M
51-2700 was used in Immunohistochemistry to replicate these findings in female rodents. Brainstem sections from the locus coeruleus (LC) and dorsal raphe nuclei (DRN) were processed for in situ hybridisation at 1 and 7 days post-bTBI.
Fri Nov 13 00:00:00 EST 2020
Phosphoinositide 3-kinase inhibitor AS605240 ameliorates streptozotocin-induced Alzheimer's disease like sporadic dementia in experimental rats.
EXCLI journal
Alluri R,Ambati SR,Routhu K,Kopalli SR,Koppula S
51-2700 was used in Western Blot to study the effects of of AS605240 (a PI3K inhibitor) on streptozotocin-induced sporadic Alzheimer's symptoms in a rat model.
Mon Sep 28 00:00:00 EDT 2020
A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice.
Experimental eye research
Korneva A,Schaub J,Jefferys J,Kimball E,Pease ME,Nawathe M,Johnson TV,Pitha I,Quigley H
51-2700 was used in Immunohistochemistry to develop a method for studying pathogenic axonal transport blockade in a mouse glaucoma model.
Wed Jul 01 00:00:00 EDT 2020
Long-term cognitive impairment without diffuse axonal injury following repetitive mild traumatic brain injury in rats.
Behavioural brain research
Tadepalli SA,Bali ZK,Bruszt N,Nagy LV,Amrein K,Fazekas B,Büki A,Czeiter E,Hernádi I
51-2700 was used in Immunohistochemistry to assess cognitive performance differences in mouse traumatic brain injury models with different time intervals between injury.
Mon Jan 27 00:00:00 EST 2020
Periventricular White Matter Alterations From Explosive Blast in a Large Animal Model: Mild Traumatic Brain Injury or "Subconcussive" Injury?
Journal of neuropathology and experimental neurology
Kim JH,Goodrich JA,Situ R,Rapuano A,Hetherington H,Du F,Parks S,Taylor W,Westmoreland T,Ling G,Bandak FA,de Lanerolle NC
51-2700 was used in Immunohistochemistry to investigate the effect of explosive blasts on the constrained head minimizing the effects of whole head motion.
Mon Jun 01 00:00:00 EDT 2020
Diffuse Axonal Injury in the Rat Brain: Axonal Injury and Oligodendrocyte Activity Following Rotational Injury.
Brain sciences
Losurdo M,Davidsson J,Sköld MK
51-2700 was used in Immunohistochemistry to assess how myelin and oligodendrocytes react to head angular-acceleration-induced traumatic brain injury.
Fri Apr 10 00:00:00 EDT 2020
Diffuse Axonal Injury in the Rat Brain: Axonal Injury and Oligodendrocyte Activity Following Rotational Injury.
Brain sciences
Losurdo M,Davidsson J,Sköld MK
51-2700 was used in Immunohistochemistry to assess how myelin and oligodendrocytes react to head angular-acceleration-induced traumatic brain injury.
Fri Apr 10 00:00:00 EDT 2020
The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport.
Cells
Bustamante HA,Cereceda K,González AE,Valenzuela GE,Cheuquemilla Y,Hernández S,Arias-Muñoz E,Cerda-Troncoso C,Bandau S,Soza A,Kausel G,Kerr B,Mardones GA,Cancino J,Hay RT,Rojas-Fernandez A,Burgos PV
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Mon Mar 23 00:00:00 EDT 2020
The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport.
Cells
Bustamante HA,Cereceda K,González AE,Valenzuela GE,Cheuquemilla Y,Hernández S,Arias-Muñoz E,Cerda-Troncoso C,Bandau S,Soza A,Kausel G,Kerr B,Mardones GA,Cancino J,Hay RT,Rojas-Fernandez A,Burgos PV
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Mon Mar 23 00:00:00 EDT 2020
Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset.
International journal of molecular sciences
Milani C,Farina F,Botto L,Massimino L,Lonati E,Donzelli E,Ballarini E,Crippa L,Marmiroli P,Bulbarelli A,Palestini P
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Sun May 24 00:00:00 EDT 2020
Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset.
International journal of molecular sciences
Milani C,Farina F,Botto L,Massimino L,Lonati E,Donzelli E,Ballarini E,Crippa L,Marmiroli P,Bulbarelli A,Palestini P
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Sun May 24 00:00:00 EDT 2020
Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in.
Neurobiology of disease
Chiasseu M,Fesharaki-Zadeh A,Saito T,Saido TC,Strittmatter SM
51-2700 was used in ELISA, Immunohistochemistry, Western Blot to reveal that rmCHI enhances accumulation of amyloid-β and hyperphosphorylated tau inclusions, as well as neuroinflammation in AppNL-F/NL-F mice.
Sun Nov 01 00:00:00 EDT 2020
Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes.
Molecular neurobiology
Chierto E,Simon A,Castoldi F,Meffre D,Cristinziano G,Sapone F,Carrete A,Borderie D,Etienne F,Rannou F,Morrison B,Massaad C,Jafarian-Tehrani M
51-2700 was used in Western Blotting to show mechanical stretch of high magnitude provokes axonal injury with significant alterations in oligodendrocyte biology that could initiate demyelination.
Sat Jun 01 00:00:00 EDT 2019
Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes.
Molecular neurobiology
Chierto E,Simon A,Castoldi F,Meffre D,Cristinziano G,Sapone F,Carrete A,Borderie D,Etienne F,Rannou F,Morrison B,Massaad C,Jafarian-Tehrani M
51-2700 was used in Western Blotting to show mechanical stretch of high magnitude provokes axonal injury with significant alterations in oligodendrocyte biology that could initiate demyelination.
Sat Jun 01 00:00:00 EDT 2019
EPPS treatment attenuates traumatic brain injury in mice by reducing Aβ burden and ameliorating neuronal autophagic flux.
Experimental neurology
Anthony Jalin AMA,Jin R,Wang M,Li G
51-2700 was used in Immunohistochemistry to investigate the neuroprotective effects of 4-(2-hydroxyethyl)-1-piperazinepropanesulphonic acid in a mouse model of traumatic brain injury.
Mon Apr 01 00:00:00 EDT 2019
Vascular phenotype of amyloid precursor protein-deficient mice.
American journal of physiology. Heart and circulatory physiology
d'Uscio LV,Katusic ZS
51-2700 was used in Western Blotting to characterize the vascular phenotype of amyloid precursor protein (APP)-knockout (APP-/-) mice.
Sat Jun 01 00:00:00 EDT 2019
Repetitive Concussive and Subconcussive Injury in a Human Tau Mouse Model Results in Chronic Cognitive Dysfunction and Disruption of White Matter Tracts, But Not Tau Pathology.
Journal of neurotrauma
Gangolli M,Benetatos J,Esparza TJ,Fountain EM,Seneviratne S,Brody DL
51-2700 was used in Immunohistochemistry to determine the effect of repetitive brain trauma in adult mice and observe changes in tau tangle accumulation.
Fri Mar 01 00:00:00 EST 2019
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.
Nature neuroscience
Gunner G,Cheadle L,Johnson KM,Ayata P,Badimon A,Mondo E,Nagy MA,Liu L,Bemiller SM,Kim KW,Lira SA,Lamb BT,Tapper AR,Ransohoff RM,Greenberg ME,Schaefer A,Schafer DP
51-2700 was used in Immunohistochemistry to identify neuron-to-microglia signaling necessary for cortical synaptic remodeling and reveal that context-dependent immune mechanisms are utilized to remodel synapses in the mammalian brain.
Mon Jul 01 00:00:00 EDT 2019
Primary Traumatic Axonopathy in Mice Subjected to Impact Acceleration: A Reappraisal of Pathology and Mechanisms with High-Resolution Anatomical Methods.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ziogas NK,Koliatsos VE
51-2700 was used in Immunohistochemistry (PFA fixed) to indicate that high resolution anatomical models of traumatic axonal injury afford a level of detail and sensitivity that is ideal for testing novel molecular and biomechanical hypotheses.
Wed Apr 18 00:00:00 EDT 2018
Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology.
The American journal of pathology
McDonald WS,Jones EE,Wojciak JM,Drake RR,Sabbadini RA,Harris NG
51-2700 was used in Immunohistochemistry to provide evidence of lysophosphatidic acid (LPA) as an early signaling molecule that contributes to the pathophysiology of traumatic brain injury (TBI), not only within hemorrhagic regions, but widespread within the brain, and especially in white matter regions.
Wed Aug 01 00:00:00 EDT 2018
Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice.
Journal of neurochemistry
Tapia-Rojas C,Inestrosa NC
51-2700 was used in Western Blotting to study, using cognitive, biochemical and histochemical analyses, how dysfunctional Wnt signaling accelerates the development of Alzheimer's disease in a mouse model.
Thu Feb 01 00:00:00 EST 2018
A Mild Traumatic Brain Injury in Mice Produces Lasting Deficits in Brain Metabolism.
Journal of neurotrauma
Lyons DN,Vekaria H,Macheda T,Bakshi V,Powell DK,Gold BT,Lin AL,Sullivan PG,Bachstetter AD
51-2700 was used in Immunohistochemistry to explore the effects of mild traumatic brain injury on brain metabolism in mice. Proton magnetic resonance spectroscopy (1H MRS) was used.
Mon Oct 15 00:00:00 EDT 2018
Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury.
Cerebral cortex (New York, N.Y. : 1991)
Vascak M,Jin X,Jacobs KM,Povlishock JT
51-2700 was used in Immunohistochemistry-immunofluorescence to show that PV interneuron DAI is a consistent and significant feature of experimental mTBI with important implications for cortical network dysfunction.
Tue May 01 00:00:00 EDT 2018
The Importance of Inter-Species Variation in Traumatic Brain Injury-Induced Alterations of Microglial-Axonal Interactions.
Frontiers in neurology
Gorse KM,Lafrenaye AD
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
A Comparative Study of Two Blast-Induced Traumatic Brain Injury Models: Changes in Monoamine and Galanin Systems Following Single and Repeated Exposure.
Frontiers in neurology
Kawa L,Kamnaksh A,Long JB,Arborelius UP,Hökfelt T,Agoston DV,Risling M
51-2700 was used in Immunohistochemistry-immunofluorescence to directly compare two established rodent models of rmbTBI, and to highlight the challenges of comparing findings from different animal models.
Thu Oct 01 00:00:00 EDT 2020
modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury.
Scientific reports
Sauerbeck AD,Fanizzi C,Kim JH,Gangolli M,Bayly PV,Wellington CL,Brody DL,Kummer TT
51-2700 was used in Immunohistochemistry to report a tunable, monitored model of murine non-surgical, difuse closed-head injury-modCHIMERA-characterized by impact as well as linear and rotational acceleration.
Wed May 16 00:00:00 EDT 2018
NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.
Autophagy
Yang C,Cai CZ,Song JX,Tan JQ,Durairajan SSK,Iyaswamy A,Wu MY,Chen LL,Yue Z,Li M,Lu JH
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunocytochemistry
Fri Jul 05 00:00:00 EDT 2019
The connectomics of brain demyelination: Functional and structural patterns in the cuprizone mouse model.
NeuroImage
Hübner NS,Mechling AE,Lee HL,Reisert M,Bienert T,Hennig J,von Elverfeldt D,Harsan LA
512700 was used in immunohistochemistry - free floating to describe functional and structural pathology-to-network signatures in the brain after cuprizone treatment
Wed Feb 01 00:00:00 EST 2017
Defining an Analytic Framework to Evaluate Quantitative MRI Markers of Traumatic Axonal Injury: Preliminary Results in a Mouse Closed Head Injury Model.
eNeuro
Haber M,Hutchinson EB,Sadeghi N,Cheng WH,Namjoshi D,Cripton P,Irfanoglu MO,Wellington C,Diaz-Arrastia R,Pierpaoli C
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Wed May 30 00:00:00 EDT 2018
Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe.
PloS one
Kallakuri S,Desai A,Feng K,Tummala S,Saif T,Chen C,Zhang L,Cavanaugh JM,King AI
51-2700 was used in immunohistochemistry - frozen section to characterize gyrencephalic swine brains exposed to true open field blasts
Thu Aug 10 00:00:00 EDT 2017
Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)42 peptides.
Journal of neurochemistry
Tapia-Rojas C,Burgos PV,Inestrosa NC
512700 was used in western blot to suggest that loss of the Wnt signaling pathway may contribute to Alzheimer's disease pathogenesis
Thu Dec 01 00:00:00 EST 2016
Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the Brain.
The Journal of biological chemistry
Qin X,Wang Y,Paudel HK
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Fri Oct 14 00:00:00 EDT 2016
Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the Brain.
The Journal of biological chemistry
Qin X,Wang Y,Paudel HK
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Fri Oct 14 00:00:00 EDT 2016
The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner.
PloS one
Stevenson JW,Conaty EA,Walsh RB,Poidomani PJ,Samoriski CM,Scollins BJ,DeGiorgis JA
51-2700 was used in immunocytochemistry to characterize organelles that bind microtubules in an ATP dependent manner by studying the amyloid precursor protein of Alzheimer's disease clusters at the organelle/microtubule interface
Tue Jul 26 00:00:00 EDT 2016
TREM2 regulates microglial cell activation in response to demyelination in vivo.
Acta neuropathologica
Cantoni C,Bollman B,Licastro D,Xie M,Mikesell R,Schmidt R,Yuede CM,Galimberti D,Olivecrona G,Klein RS,Cross AH,Otero K,Piccio L
51-2700 was used in immunocytochemistry to investigate the contribution of TREM2 to microglia function in vivo
Sun Mar 01 00:00:00 EST 2015
TREM2 regulates microglial cell activation in response to demyelination in vivo.
Acta neuropathologica
Cantoni C,Bollman B,Licastro D,Xie M,Mikesell R,Schmidt R,Yuede CM,Galimberti D,Olivecrona G,Klein RS,Cross AH,Otero K,Piccio L
51-2700 was used in immunocytochemistry to investigate the contribution of TREM2 to microglia function in vivo
Sun Mar 01 00:00:00 EST 2015
Traumatic brain injury-induced axonal phenotypes react differently to treatment.
Acta neuropathologica
Hånell A,Greer JE,McGinn MJ,Povlishock JT
51-2700 was used in immunohistochemistry - free floating to characterize axonal injury over time.
Sun Feb 01 00:00:00 EST 2015
Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rolyan H,Tyurina YY,Hernandez M,Amoscato AA,Sparvero LJ,Nmezi BC,Lu Y,Estécio MR,Lin K,Chen J,He RR,Gong P,Rigatti LH,Dupree J,Bayır H,Kagan VE,Casaccia P,Padiath QS
51-2700 was used in immunohistochemistry - frozen section to elucidate the mechanisms by which increased LMNB1 levels cause autosomal dominant leukodystrophy
Wed Aug 26 00:00:00 EDT 2015
A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments.
Experimental neurology
del Mar N,von Buttlar X,Yu AS,Guley NH,Reiner A,Honig MG
51-2700 was used in immunohistochemistry to describe the development of a closed-body model of spinal cord injury in mice
Tue Sep 01 00:00:00 EDT 2015
Neurotransmitter Systems in a Mild Blast Traumatic Brain Injury Model: Catecholamines and Serotonin.
Journal of neurotrauma
Kawa L,Arborelius UP,Yoshitake T,Kehr J,Hökfelt T,Risling M,Agoston D
51-2700 was used in immunohistochemistry - frozen section to examine the role of the monoaminergic system in mild blast-induced traumatic brain injury.
Sat Aug 15 00:00:00 EDT 2015
Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching.
Cerebral cortex (New York, N.Y. : 1991)
Yan Y,Eipper BA,Mains RE
51-2700 was used in western blot to report that Kal9 and Kal12 mediate dendritic maturation in early development
Thu Oct 01 00:00:00 EDT 2015
Array tomography for the detection of non-dilated, injured axons in traumatic brain injury.
Journal of neuroscience methods
Bennett RE,Brody DL
51-2700 was used in immunohistochemistry - frozen section to discuss the limitations assessing axonal injury by microscopy
Thu Apr 30 00:00:00 EDT 2015
Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig.
Journal of neuroinflammation
Lafrenaye AD,Todani M,Walker SA,Povlishock JT
51-2700 was used in immunohistochemistry to determine the relationship between injured axons after mild traumatic brain injury in pigs and microglia processes
Tue Oct 06 00:00:00 EDT 2015
Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury.
Journal of neuroinflammation
Gyoneva S,Kim D,Katsumoto A,Kokiko-Cochran ON,Lamb BT,Ransohoff RM
51-2700 was used in immunohistochemistry to assess the deletion of Ccr2 and cavity size and tau pathology after mild traumatic brain injury
Thu Dec 03 00:00:00 EST 2015
Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma.
PloS one
Quigley HA,Pitha IF,Welsbie DS,Nguyen C,Steinhart MR,Nguyen TD,Pease ME,Oglesby EN,Berlinicke CA,Mitchell KL,Kim J,Jefferys JJ,Kimball EC
51-2700 was used in immunohistochemistry to assess Losartan treatment on experimental glaucoma
Fri Jun 10 00:00:00 EDT 2016
Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy.
PloS one
Cavieres VA,González A,Muñoz VC,Yefi CP,Bustamante HA,Barraza RR,Tapia-Rojas C,Otth C,Barrera MJ,González C,Mardones GA,Inestrosa NC,Burgos PV
51-2700 was used in western blot to show that IDN5706 promotes iAPP degradation by activating Atg5-dependent autophagy.
Tue May 24 00:00:00 EDT 2016
Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy.
PloS one
Cavieres VA,González A,Muñoz VC,Yefi CP,Bustamante HA,Barraza RR,Tapia-Rojas C,Otth C,Barrera MJ,González C,Mardones GA,Inestrosa NC,Burgos PV
51-2700 was used in western blot to show that IDN5706 promotes iAPP degradation by activating Atg5-dependent autophagy.
Tue May 24 00:00:00 EDT 2016
Blast overpressure induced axonal injury changes in rat brainstem and spinal cord.
Journal of neurosciences in rural practice
Kallakuri S,Purkait HS,Dalavayi S,VandeVord P,Cavanaugh JM
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Tue Jan 12 00:00:00 EST 2016
APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation.
Cell death & disease
Shu R,Wong W,Ma QH,Yang ZZ,Zhu H,Liu FJ,Wang P,Ma J,Yan S,Polo JM,Bernard CC,Stanton LW,Dawe GS,Xiao ZC
51-2700 was used in ChIP Assay to indicate that AICD has a novel role in suppression of neuronal differentiation via transcriptional regulation of miR-663 in human neural stem cells.
Thu Feb 19 00:00:00 EST 2015
Moderately elevated intracranial pressure after diffuse traumatic brain injury is associated with exacerbated neuronal pathology and behavioral morbidity in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Lafrenaye AD,Krahe TE,Povlishock JT
51-2700 was used in immunohistochemistry - free floating to assess if subischemic levels of elevated intracranial pressure without hematoma/contusion contribute to increased morbidity/mortality
Wed Oct 01 00:00:00 EDT 2014
Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model.
Journal of neurotrauma
Washington PM,Morffy N,Parsadanian M,Zapple DN,Burns MP
51-2700 was used in immunohistochemistry to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury
Wed Jan 01 00:00:00 EST 2014
Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model.
Journal of neurotrauma
Washington PM,Morffy N,Parsadanian M,Zapple DN,Burns MP
51-2700 was used in immunohistochemistry to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury
Wed Jan 01 00:00:00 EST 2014
Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury.
Journal of neurotrauma
Bennett RE,Brody DL
51-2700 was used in immunohistochemistry - frozen section to study the contribution of microglia to axon degeneration after repetitive closed-skull traumatic brain injury using CD11b-thymidine kinase mice
Wed Oct 01 00:00:00 EDT 2014
Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.
International journal of Alzheimer's disease
Toyn JH,Thompson LA,Lentz KA,Meredith JE,Burton CR,Sankaranararyanan S,Guss V,Hall T,Iben LG,Krause CM,Krause R,Lin XA,Pierdomenico M,Polson C,Robertson AS,Denton RR,Grace JE,Morrison J,Raybon J,Zhuo X,Snow K,Padmanabha R,Agler M,Esposito K,Harden D,Prack M,Varma S,Wong V,Zhu Y,Zvyaga T,Gerritz S,Marcin LR,Higgins MA,Shi J,Wei C,Cantone JL,Drexler DM,Macor JE,Olson RE,Ahlijanian MK,Albright CF
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Wed Aug 06 00:00:00 EDT 2014
Fragile X mental retardation protein expression in Alzheimer's disease.
Frontiers in genetics
Renoux AJ,Carducci NM,Ahmady AA,Todd PK
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Tue Dec 02 00:00:00 EST 2014
Endothelial nitric oxide deficiency promotes Alzheimer's disease pathology.
Journal of neurochemistry
Austin SA,Santhanam AV,Hinton DJ,Choi DS,Katusic ZS
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Sun Dec 01 00:00:00 EST 2013
AAD-2004 Attenuates Progressive Neuronal Loss in the Brain of Tg-betaCTF99/B6 Mouse Model of Alzheimer Disease.
Experimental neurobiology
Baek IS,Kim TK,Seo JS,Lee KW,Lee YA,Cho J,Gwag BJ,Han PL
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Fri Mar 01 00:00:00 EST 2013
Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat.
The European journal of neuroscience
Flygt J,Djupsjö A,Lenne F,Marklund N
51-2700 was used in western blot to assess myelin loss and oligodendrocyte death following traumatic brain injury.
Mon Jul 01 00:00:00 EDT 2013
Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat.
The European journal of neuroscience
Flygt J,Djupsjö A,Lenne F,Marklund N
51-2700 was used in western blot to assess myelin loss and oligodendrocyte death following traumatic brain injury.
Mon Jul 01 00:00:00 EDT 2013
Cortical hypoexcitation defines neuronal responses in the immediate aftermath of traumatic brain injury.
PloS one
Johnstone VP,Yan EB,Alwis DS,Rajan R
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Tue Dec 17 00:00:00 EST 2013
Clinically relevant intronic splicing enhancer mutation in myelin proteolipid protein leads to progressive microglia and astrocyte activation in white and gray matter regions of the brain.
Journal of neuroinflammation
Bachstetter AD,Webster SJ,Van Eldik LJ,Cambi F
51-2700 was used in immunohistochemistry - frozen section to assess temporal and spatial onset of the reactive glia response in a clinically relevant form of Pelizaeus-Merzbacher disease.
Thu Dec 05 00:00:00 EST 2013
Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Lafrenaye AD,McGinn MJ,Povlishock JT
51-2700 was used in immunohistochemistry to study the neuronal somatic and axonal damage that occurs during elevated intracranial pressure.
Mon Oct 01 00:00:00 EDT 2012
Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bettayeb K,Oumata N,Zhang Y,Luo W,Bustos V,Galons H,Greengard P,Meijer L,Flajolet M
Sat Dec 01 00:00:00 EST 2012
Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bettayeb K,Oumata N,Zhang Y,Luo W,Bustos V,Galons H,Greengard P,Meijer L,Flajolet M
Sat Dec 01 00:00:00 EST 2012
Internal jugular vein compression mitigates traumatic axonal injury in a rat model by reducing the intracranial slosh effect.
Neurosurgery
Smith DW,Bailes JE,Fisher JA,Robles J,Turner RC,Mills JD
51-2700 was used in immunohistochemistry to discuss the use of helmets to prevent traumatic brain injury.
Thu Mar 01 00:00:00 EST 2012
Secondary damage caused by CD11b+ microglia following diffuse axonal injury in rats.
The journal of trauma and acute care surgery
Jia X,Cong B,Wang S,Dong L,Ma C,Li Y
51-2700 was used in immunohistochemistry to investigate diffuse axonal injury.
Thu Nov 01 00:00:00 EDT 2012
Temporal assessment of traumatic axonal injury in the rat corpus callosum and optic chiasm.
Brain research
Zakaria N,Kallakuri S,Bandaru S,Cavanaugh JM
51-2700 was used in immunohistochemistry to perform a time course to study impaired axoplasmic transport and neurofilament compaction.
Fri Jul 27 00:00:00 EDT 2012
Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice.
Journal of neuropathology and experimental neurology
Tran HT,Sanchez L,Brody DL
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Wed Feb 01 00:00:00 EST 2012
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.
Molecular neurodegeneration
Youmans KL,Tai LM,Kanekiyo T,Stine WB,Michon SC,Nwabuisi-Heath E,Manelli AM,Fu Y,Riordan S,Eimer WA,Binder L,Bu G,Yu C,Hartley DM,LaDu MJ
Fri Mar 16 00:00:00 EDT 2012
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.
Molecular neurodegeneration
Youmans KL,Tai LM,Kanekiyo T,Stine WB,Michon SC,Nwabuisi-Heath E,Manelli AM,Fu Y,Riordan S,Eimer WA,Binder L,Bu G,Yu C,Hartley DM,LaDu MJ
Fri Mar 16 00:00:00 EDT 2012
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.
Molecular neurodegeneration
Youmans KL,Tai LM,Kanekiyo T,Stine WB,Michon SC,Nwabuisi-Heath E,Manelli AM,Fu Y,Riordan S,Eimer WA,Binder L,Bu G,Yu C,Hartley DM,LaDu MJ
Fri Mar 16 00:00:00 EDT 2012
Human neural progenitors from different foetal forebrain regions remyelinate the adult mouse spinal cord.
Brain : a journal of neurology
Buchet D,Garcia C,Deboux C,Nait-Oumesmar B,Baron-Van Evercooren A
51-2700 was used in immunohistochemistry to examine the oligodendrogenic potential of different human fetal forebrain regions during the first trimester of gestation.
Fri Apr 01 00:00:00 EDT 2011
Omega-3 fatty acid supplementation and reduction of traumatic axonal injury in a rodent head injury model.
Journal of neurosurgery
Mills JD,Bailes JE,Sedney CL,Hutchins H,Sears B
51-2700 was used in immunohistochemistry to assess the benefits of O3FA supplementation following diffuse axonal injury in rats
Sat Jan 01 00:00:00 EST 2011
Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studies.
Journal of neurotrauma
Pleasant JM,Carlson SW,Mao H,Scheff SW,Yang KH,Saatman KE
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunohistochemistry
Tue Nov 01 00:00:00 EDT 2011
Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration model.
Journal of neurotrauma
Li Y,Zhang L,Kallakuri S,Zhou R,Cavanaugh JM
51-2700 was used in immunohistochemistry to study traumatic axonal injury in rats.
Thu Sep 01 00:00:00 EDT 2011
Rodent model of direct cranial blast injury.
Journal of neurotrauma
Kuehn R,Simard PF,Driscoll I,Keledjian K,Ivanova S,Tosun C,Williams A,Bochicchio G,Gerzanich V,Simard JM
51-2700 was used in immunohistochemistry - frozen section to characterize a rodent model of direct cranial blast injury.
Sat Oct 01 00:00:00 EDT 2011
A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization.
Journal of neuropathology and experimental neurology
Koliatsos VE,Cernak I,Xu L,Song Y,Savonenko A,Crain BJ,Eberhart CG,Frangakis CE,Melnikova T,Kim H,Lee D
51-2700 was used in immunohistochemistry - frozen section to investigate the effects of blast injury on the parenchymatous organs of mice.
Sun May 01 00:00:00 EDT 2011
Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
PloS one
Westmark CJ,Westmark PR,O'Riordan KJ,Ray BC,Hervey CM,Salamat MS,Abozeid SH,Stein KM,Stodola LA,Tranfaglia M,Burger C,Berry-Kravis EM,Malter JS
Mon Mar 26 00:00:00 EDT 2012
A new model to produce sagittal plane rotational induced diffuse axonal injuries.
Frontiers in neurology
Davidsson J,Risling M
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Thu Jul 14 00:00:00 EDT 2011
PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.
Journal of lipid research
Liu M,Wu G,Baysarowich J,Kavana M,Addona GH,Bierilo KK,Mudgett JS,Pavlovic G,Sitlani A,Renger JJ,Hubbard BK,Fisher TS,Zerbinatti CV
51-2700 was used in western blot to test if proprotein convertase subtilisin/kexin type 9 modulates the levels of low-density lipoprotein receptor and other membrane-bound proteins in the adult mouse brain.
Wed Sep 01 00:00:00 EDT 2010
PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.
Journal of lipid research
Liu M,Wu G,Baysarowich J,Kavana M,Addona GH,Bierilo KK,Mudgett JS,Pavlovic G,Sitlani A,Renger JJ,Hubbard BK,Fisher TS,Zerbinatti CV
51-2700 was used in western blot to test if proprotein convertase subtilisin/kexin type 9 modulates the levels of low-density lipoprotein receptor and other membrane-bound proteins in the adult mouse brain.
Wed Sep 01 00:00:00 EDT 2010
Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study.
Journal of neurotrauma
Homsi S,Piaggio T,Croci N,Noble F,Plotkine M,Marchand-Leroux C,Jafarian-Tehrani M
51-2700 was used in immunohistochemistry to assess the effects of acute treatment with minocycline on traumatic brain injury
Sat May 01 00:00:00 EDT 2010
Docosahexaenoic acid reduces traumatic axonal injury in a rodent head injury model.
Journal of neurotrauma
Bailes JE,Mills JD
51-2700 was used in immunohistochemistry to assess the benefits of DHA treatment following diffuse axonal injury in rats
Wed Sep 01 00:00:00 EDT 2010
Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
The Journal of biological chemistry
Liang B,Duan BY,Zhou XP,Gong JX,Luo ZG
51-2700 was used in western blot to elucidate the mechanism of calpain during Alzheimer's disease progression
Fri Sep 03 00:00:00 EDT 2010
Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
The Journal of biological chemistry
Liang B,Duan BY,Zhou XP,Gong JX,Luo ZG
51-2700 was used in western blot to elucidate the mechanism of calpain during Alzheimer's disease progression
Fri Sep 03 00:00:00 EDT 2010
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Muresan V,Varvel NH,Lamb BT,Muresan Z
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2009
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Muresan V,Varvel NH,Lamb BT,Muresan Z
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2009
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Muresan V,Varvel NH,Lamb BT,Muresan Z
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2009
The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Muresan V,Varvel NH,Lamb BT,Muresan Z
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Immunofluorescence
Wed Mar 18 00:00:00 EDT 2009
Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress.
Journal of neurochemistry
Lee KW,Kim JB,Seo JS,Kim TK,Im JY,Baek IS,Kim KS,Lee JK,Han PL
51-2700 was used in western blot to study the mechanism by which behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice.
Thu Jan 01 00:00:00 EST 2009
Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.
Neurobiology of aging
Broytman O,Westmark PR,Gurel Z,Malter JS
51-2700 was used in RNA immunoprecipitation and immunocytochemistry to identify proteins that bind to the 52sce of the amyloid precursor protein
Tue Dec 01 00:00:00 EST 2009
SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice.
Brain research
Seo JS,Kim TK,Leem YH,Lee KW,Park SK,Baek IS,Kim KS,Im GJ,Lee SM,Park YH,Han PL
51-2700 was used in ELISA and western blot to study the effect of an oleanolic-glycoside saponin on anti-oxidant activity and Abeta levels in the brain of Tg2576 mice.
Thu Mar 19 00:00:00 EDT 2009
SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice.
Brain research
Seo JS,Kim TK,Leem YH,Lee KW,Park SK,Baek IS,Kim KS,Im GJ,Lee SM,Park YH,Han PL
51-2700 was used in ELISA and western blot to study the effect of an oleanolic-glycoside saponin on anti-oxidant activity and Abeta levels in the brain of Tg2576 mice.
Thu Mar 19 00:00:00 EDT 2009
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
The Journal of clinical investigation
Wahrle SE,Jiang H,Parsadanian M,Kim J,Li A,Knoten A,Jain S,Hirsch-Reinshagen V,Wellington CL,Bales KR,Paul SM,Holtzman DM
Published figure using beta Amyloid polyclonal antibody (Product # 51-2700) in Western Blot
Fri Feb 01 00:00:00 EST 2008
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Journal of neurochemistry
Ryoo SR,Cho HJ,Lee HW,Jeong HK,Radnaabazar C,Kim YS,Kim MJ,Son MY,Seo H,Chung SH,Song WJ
51-2700 was used in western blot to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase A in Down syndrome brains.
Sat Mar 01 00:00:00 EST 2008
Myopathy with tubulin-reactive inclusions in two cats.
Acta neuropathologica
Shelton GD,Sturges BK,Lyons LA,Williams DC,Aleman M,Jiang Y,Mizisin AP
51-2700 was used in immunohistochemistry to discuss features present in feline myopathy
Thu Nov 01 00:00:00 EDT 2007
FMRP mediates mGluR5-dependent translation of amyloid precursor protein.
PLoS biology
Westmark CJ,Malter JS
51-2700 was used in immunoprecipitation to elucidate the molecular mechanism that links Alzheimer disease and fragile X syndrome
Thu Mar 01 00:00:00 EST 2007
Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.
The Journal of biological chemistry
Nizzari M,Venezia V,Repetto E,Caorsi V,Magrassi R,Gagliani MC,Carlo P,Florio T,Schettini G,Tacchetti C,Russo T,Diaspro A,Russo C
51-2700 was used in immunoprecipitation to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle
Fri May 04 00:00:00 EDT 2007
Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.
The Journal of biological chemistry
Nizzari M,Venezia V,Repetto E,Caorsi V,Magrassi R,Gagliani MC,Carlo P,Florio T,Schettini G,Tacchetti C,Russo T,Diaspro A,Russo C
51-2700 was used in immunoprecipitation to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle
Fri May 04 00:00:00 EDT 2007
Evolution of a neuroprotective function of central nervous system myelin.
The Journal of cell biology
Yin X,Baek RC,Kirschner DA,Peterson A,Fujii Y,Nave KA,Macklin WB,Trapp BD
Mon Jan 30 00:00:00 EST 2006
Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Park JH,Gimbel DA,GrandPre T,Lee JK,Kim JE,Li W,Lee DH,Strittmatter SM
Wed Feb 01 00:00:00 EST 2006
Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Park JH,Gimbel DA,GrandPre T,Lee JK,Kim JE,Li W,Lee DH,Strittmatter SM
Wed Feb 01 00:00:00 EST 2006
Amyloid precursor protein modulates ERK-1 and -2 signaling.
Annals of the New York Academy of Sciences
Venezia V,Nizzari M,Repetto E,Violani E,Corsaro A,Thellung S,Villa V,Carlo P,Schettini G,Florio T,Russo C
51-2700 was used in immunoprecipitation and western blot to examine the interaction between amyloid precursor protein and ShcA/Grb2
Fri Dec 01 00:00:00 EST 2006
Selective induction of ultrastructural (neurofilament) compaction in axons by means of a new head-injury apparatus.
Journal of neuroscience methods
Pál J,Tóth Z,Farkas O,Kellényi L,Dóczi T,Gallyas F
51-2700 was used in immunohistochemistry - paraffin section to develop a new weight-drop head-injury apparatus and assess the treated rats
Thu Jun 15 00:00:00 EDT 2006
Ginkgo biloba extract (Egb 761) inhibits beta-amyloid production by lowering free cholesterol levels.
The Journal of nutritional biochemistry
Yao ZX,Han Z,Drieu K,Papadopoulos V
Wed Dec 01 00:00:00 EST 2004
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
The Journal of biological chemistry
Cam JA,Zerbinatti CV,Knisely JM,Hecimovic S,Li Y,Bu G
Fri Jul 09 00:00:00 EDT 2004
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
The Journal of biological chemistry
Cam JA,Zerbinatti CV,Knisely JM,Hecimovic S,Li Y,Bu G
Fri Jul 09 00:00:00 EDT 2004
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
The Journal of biological chemistry
Cam JA,Zerbinatti CV,Knisely JM,Hecimovic S,Li Y,Bu G
Fri Jul 09 00:00:00 EDT 2004
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
The Journal of biological chemistry
Cam JA,Zerbinatti CV,Knisely JM,Hecimovic S,Li Y,Bu G
Fri Jul 09 00:00:00 EDT 2004
Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.
The Journal of biological chemistry
Ghersi E,Noviello C,D'Adamio L
Fri Nov 19 00:00:00 EST 2004
Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease.
Aging cell
Satpute-Krishnan P,DeGiorgis JA,Bearer EL
Mon Dec 01 00:00:00 EST 2003
Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease.
Aging cell
Satpute-Krishnan P,DeGiorgis JA,Bearer EL
Mon Dec 01 00:00:00 EST 2003
A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading.
Stapp car crash journal
Morrison B,Cater HL,Wang CC,Thomas FC,Hung CT,Ateshian GA,Sundstrom LE
51-2700 was used in immunohistochemistry to develop and characterize a tissue culture model of traumatic brain injury
Wed Oct 01 00:00:00 EDT 2003
Antibodies to the C-terminus of the beta-amyloid precursor protein (APP): a site specific marker for the detection of traumatic axonal injury.
Brain research
Stone JR,Singleton RH,Povlishock JT
Fri Jul 21 00:00:00 EDT 2000
Antibodies to the C-terminus of the beta-amyloid precursor protein (APP): a site specific marker for the detection of traumatic axonal injury.
Brain research
Stone JR,Singleton RH,Povlishock JT
Fri Jul 21 00:00:00 EDT 2000
Sporadic inclusion body myositis correlates with increased expression and cross-linking by transglutaminases 1 and 2.
The Journal of biological chemistry
Choi YC,Park GT,Kim TS,Sunwoo IN,Steinert PM,Kim SY
Fri Mar 24 00:00:00 EST 2000
Sporadic inclusion body myositis correlates with increased expression and cross-linking by transglutaminases 1 and 2.
The Journal of biological chemistry
Choi YC,Park GT,Kim TS,Sunwoo IN,Steinert PM,Kim SY
Fri Mar 24 00:00:00 EST 2000
.jpg?time=20240507)
.jpg?time=20240507?time=20240507 "beta Amyloid Antibody (51-2700) in IHC (Free)")
