Product References
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Neoplasma
Li GH,Liu X,Feng LJ,Zhang L
Sun Aug 20 00:00:00 EDT 2023
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
iScience
Li Y,Zhang L,Mao M,He L,Wang T,Pan Y,Zhao X,Li Z,Mu X,Qian Y,Qiu J
Fri May 19 00:00:00 EDT 2023
Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.
Cancer science
Zuo BW,Yao WX,Fang MD,Ren J,Tu LL,Fan RJ,Zhang YM
Mon May 01 00:00:00 EDT 2023
Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer.
Cancers
Han L,Dai W,Luo W,Ye L,Fang H,Mo S,Li Q,Xu Y,Wang R,Cai G
Tue Jan 17 00:00:00 EST 2023
MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells.
In vitro cellular & developmental biology. Animal
Pan C,Fei Q,Jin J,Zheng J,Wu D,Li H,Huang X,Kong X
Sun Jan 01 00:00:00 EST 2023
Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).
Journal of orthopaedic translation
Wang X,Tan Y,Liu F,Wang J,Liu F,Zhang Q,Li J
Wed Mar 01 00:00:00 EST 2023
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Stem cells and development
Li T,Tang Q,Xu J,Ye X,Chen K,Zhong J,Zhu J,Lu S,Zhu T
Fri Sep 01 00:00:00 EDT 2023
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Molecules (Basel, Switzerland)
He Y,Luo M,Lei S,Zeng Z,Chen T,Wu Y,Wang D,Wang L,Wang L
Sun Feb 12 00:00:00 EST 2023
Recombinant human angiotensin-converting enzyme 2 plays a protective role in mice with sepsis-induced cardiac dysfunction through multiple signaling pathways dependent on converting angiotensin II to angiotensin 1-7.
Annals of translational medicine
Wu C,Chen Y,Zhou P,Hu Z
Sun Jan 15 00:00:00 EST 2023
Metastatic effects of environmental carcinogens mediated by MAPK and UPR pathways with an in vivo Drosophila Model.
Journal of hazardous materials
Fangninou FF,Yu Z,Li Z,Guadie A,Li W,Xue L,Yin D
Thu Jan 05 00:00:00 EST 2023
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Heliyon
Meng D,Deng X,Wu Y,Wu J,Zhang Y,Zhang J,Zhao Y,Che Y
Thu Jun 01 00:00:00 EDT 2023
Levetiracetam attenuates diabetes-associated cognitive impairment and microglia polarization by suppressing neuroinflammation.
Frontiers in pharmacology
Zhang YY,Wang L,Guo H,Han TT,Chang YH,Cui XC
Tue May 23 00:00:00 EDT 2023
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Transplantation and cellular therapy
Wang X,Zhou Y,Sun Q,Zhang Q,Zhou H,Zhang J,Du Y,Wang Y,Yuan K,Xu L,Zhang M,Yan D,Zeng L,Xu K,Sang W
Tue Aug 01 00:00:00 EDT 2023
Deficiency of S100 calcium binding protein A9 attenuates vascular dysfunction in aged mice.
Redox biology
Zhao B,Yu J,Luo Y,Xie M,Qu C,Shi Q,Wang X,Zhao X,Kong L,Zhao Y,Guo Y
Sat Jul 01 00:00:00 EDT 2023
Naringenin Attenuates Isoprenaline-Induced Cardiac Hypertrophy by Suppressing Oxidative Stress through the AMPK/NOX2/MAPK Signaling Pathway.
Nutrients
Li Y,He B,Zhang C,He Y,Xia T,Zeng C
Thu Mar 09 00:00:00 EST 2023
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Experimental and therapeutic medicine
Qian X,Xiong S,Chen Q,Zhang J,Xie J
Sat Apr 01 00:00:00 EDT 2023
Study on the Mechanism of Jiaotai Pill Intervention on Insomnia Animal Model Based on Gut Microbiome and Metabolomics.
Evidence-based complementary and alternative medicine : eCAM
Yang Y,Liu J,Ou H,Ma X,Li J,Shao B,Jin R,Zhao J
Sun Jun 04 00:00:00 EDT 2023
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Journal of ethnopharmacology
Liu J,Yang Y,He Y,Feng C,Ou H,Yang J,Chen Y,You F,Shao B,Bao J,Guan X,Chen F,Zhao P
Sat Mar 25 00:00:00 EDT 2023
Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.
Environmental science & technology
Zhang L,Shen L,Huang Y,Cui S,Zhao Q,Zhang C,Zhuang S,Jiang G
Tue Jul 11 00:00:00 EDT 2023
CHMP4A stimulates CD8+ T-lymphocyte infiltration and inhibits breast tumor growth via the LSD1/IFNβ axis.
Cancer science
Song S,Zhang D,Chen J,Qi L,Zhang M,Yang X,Ye T,Ye Q,Lin J
Tue Aug 01 00:00:00 EDT 2023
11β-Hydroxysteroid dehydrogenase type 1 amplifies inflammation in LPS-induced THP-1 cells.
Iranian journal of basic medical sciences
Luo L,Zhu D,Zhang Z,Zeng H,Huang M,Zhou S
Wed Mar 01 00:00:00 EST 2023
Oxidative Stress-mediated Sprouty-related Protein with an EVH1 Domain 1 Down-regulation Contributes to Resisting Oxidative Injury in Microglia.
Neuroscience
Wei L,Li X,Wei Q,Chen L,Xu L,Zhou P
Mon Aug 21 00:00:00 EDT 2023
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Environmental pollution (Barking, Essex : 1987)
Cui M,He Q,Wang Z,Yu Y,Gao H,Liu Z,Peng H,Wang H,Zhang X,Li D,Chen L,Xing X,Xiao Y,Chen W,Wang Q
Tue Aug 01 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
International immunopharmacology
Shen PC,Huang SH,Liu ZM,Lu CC,Chou SH,Tien YC
Sat Jul 01 00:00:00 EDT 2023
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
International immunopharmacology
Wang P,Li T,Niu C,Sun S,Liu D
Wed Mar 01 00:00:00 EST 2023
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Ecotoxicology and environmental safety
Li X,Wang W,Hou Y,Li G,Yi H,Cui S,Zhang J,He X,Zhao H,Yang Z,Qiu Y,Liu Z,Xie J
Thu Jun 01 00:00:00 EDT 2023
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang H,Li X,Zha D,Lin H,Yang L,Wang Y,Xu L,Wang L,Lei T,Zhou Z,Xiao YF,Xin HB,Fu M,Qian Y
Tue Aug 01 00:00:00 EDT 2023
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Genomics
Cai X,Zhu S
Mon May 01 00:00:00 EDT 2023
Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.
Journal of translational medicine
Chen XS,Cui JR,Meng XL,Wang SH,Wei W,Gao YL,Shou ST,Liu YC,Chai YF
Mon Jan 02 00:00:00 EST 2023
The role of calcium-sensing receptor in ginsenoside Rg1 promoting reendothelialization to inhibit intimal hyperplasia after balloon injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xu S,Hu A,Chen J,Shuai Z,Liu T,Deng J,Li L,Gong Q,He Z,Yu L
Sat Jul 01 00:00:00 EDT 2023
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Frontiers in pharmacology
Xiong D,Gao F,Shao J,Pan Y,Wang S,Wei D,Ye S,Chen Y,Chen R,Yue B,Li J,Chen J
Sat Apr 01 00:00:00 EDT 2023
Blocking circadian clock factor Rev-erbα inhibits growth plate chondrogenesis via up-regulating MAPK-ERK1/2 pathway.
Cell cycle (Georgetown, Tex.)
Qian Z,Liu Z,Feng Z,Cai Z,Qiu Y,Zhu Z
Sun Jan 01 00:00:00 EST 2023
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Current issues in molecular biology
Huang YK,Chang KC,Li CY,Lieu AS,Lin CL
Thu Apr 13 00:00:00 EDT 2023
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
International immunopharmacology
Ning W,Gao G,Zhou Y,Li WQ,Yang HH,Duan XB,Li X,Gong YB,Li D,Guo R
Wed Mar 01 00:00:00 EST 2023
DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages.
Inflammation
Huangfu N,Ma H,Tian M,Zhang J,Wang Y,Li Z,Chen X,Cui H
Sun Oct 01 00:00:00 EDT 2023
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Bioorganic chemistry
Zhang J,Sun Y,Sun C,Shang D
Wed Mar 01 00:00:00 EST 2023
Antiangiogenic potential of Lepista nuda extract suppressing MAPK/p38 signaling-mediated developmental angiogenesis in zebrafish and HUVECs.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Deshmukh D,Hsu YF,Chiu CC,Jadhao M,Hsu SCN,Hu SY,Yang SH,Liu W
Wed Mar 01 00:00:00 EST 2023
Inhibition effect of 1-acetoxy-6α-(2-methylbutyryl)eriolanolide toward soluble epoxide hydrolase: Multispectral analysis, molecular dynamics simulation, biochemical, and in vitro cell-based studies.
International journal of biological macromolecules
Zhang J,Yang FY,Zhu QM,Zhang WH,Zhang M,Yi J,Wang Y,Zhang HL,Liang GB,Yan JK,Sun CP
Sun Apr 30 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
Docosahexaenoic Acid Attenuates Radiation-Induced Myocardial Fibrosis by Inhibiting the p38/ET-1 Pathway in Cardiomyocytes.
International journal of radiation oncology, biology, physics
Liu Y,Chen P,Liu T,Cheng B,Sun C,Xin H,Wen Z,Cheng Y
Sat Apr 01 00:00:00 EDT 2023
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
Cell biology international
Qin D,Lei Y,Xie W,Zheng Q,Peng Z,Liu Y,Dai B,Ma T,Wei P,Gao C,Guo X,Gao J,Zhao J,Du J,Zeng Q,Zhang Z,Dong X,Shen H
Wed Mar 01 00:00:00 EST 2023
Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro.
European journal of pharmacology
Sun H,Bai J,Sun Y,Zhen D,Fu D,Wang Y,Wei C
Wed Feb 15 00:00:00 EST 2023
RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse.
Journal of translational medicine
Chen Y,Tang R,Xiong W,Zhang F,Wang N,Xie B,Cao J,Chen Z,Ma C
Sun Jun 18 00:00:00 EDT 2023
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction.
Respiratory research
Wu Z,Zhu L,Nie X,Liu Y,Zhang X,Qi Y
Wed Mar 15 00:00:00 EDT 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 EDT 2023
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
PLoS genetics
Qin S,Wang G,Chen L,Geng H,Zheng Y,Xia C,Wu S,Yao J,Deng L
Wed Feb 01 00:00:00 EST 2023
Deciphering the underlying wound healing mechanisms of Streptocaulon juventas (Lour.) Merr. by integrating network pharmacology, transcriptomics, and experimental validation.
Journal of ethnopharmacology
Li Y,Zang J,Wang X,Feng X,Qiu F
Fri Feb 10 00:00:00 EST 2023
Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathway.
Frontiers in pharmacology
Zhu J,Li Z,Yin F,Yu X,Lu Y,Zhou T,Gong F,Xu Z
Tue May 09 00:00:00 EDT 2023
L-Theanine mediates the p38MAPK signaling pathway to alleviate heat-induced oxidative stress and inflammation in mice.
Food & function
Liu K,Liu E,Lin L,Hu Y,Yuan Y,Xiao W
Mon Feb 21 00:00:00 EST 2022
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
BMC molecular and cell biology
Zhu Z,Zhao Z,Chen X,Chu Z,He Y,Tan Y,Zhou J,Tang C
Thu Sep 29 00:00:00 EDT 2022
Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Su D,Liao L,Zeng Q,Liao Z,Liu Y,Jin C,Zhu G,Chen C,Yang M,Ai Z,Song Y
Sat Jan 01 00:00:00 EST 2022
Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Su D,Liao L,Zeng Q,Liao Z,Liu Y,Jin C,Zhu G,Chen C,Yang M,Ai Z,Song Y
Sat Jan 01 00:00:00 EST 2022
6-Gingerol exerts a protective effect against hypoxic injury through the p38/Nrf2/HO-1 and p38/NF-κB pathway in H9c2 cells.
The Journal of nutritional biochemistry
Han X,Liu P,Zheng B,Zhang M,Zhang Y,Xue Y,Liu C,Chu X,Wang X,Sun S,Chu L
Wed Jun 01 00:00:00 EDT 2022
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
European journal of medicinal chemistry
Liang JJ,Yu WL,Yang L,Qin KM,Yin YP,Li D,Ni YH,Yan JJ,Zhong YX,Deng ZX,Hong K
Sun Jun 05 00:00:00 EDT 2022
CMTM6 as a candidate risk gene for cervical cancer: Comprehensive bioinformatics study.
Frontiers in molecular biosciences
Huang X,Liu W,Liu C,Hu J,Wang B,Ren A,Huang X,Yuan Y,Liu J,Li M
Wed Jan 11 00:00:00 EST 2023
A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells.
Stem cell research & therapy
Wang L,Gao T,Li Y,Xie Y,Zeng S,Tai C,Feng Y,Shen P,Wang B
Fri Jun 17 00:00:00 EDT 2022
CircRNA DDX21 acts as a prognostic factor and sponge of miR-1264/QKI axis to weaken the progression of triple-negative breast cancer.
Clinical and translational medicine
Huang R,Yang Z,Liu Q,Liu B,Ding X,Wang Z
Sun May 01 00:00:00 EDT 2022
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
The Journal of investigative dermatology
Zhou Q,Gong J,Bi J,Yang X,Zhang L,Lu C,Li L,Chen M,Cai J,Yang R,Li X,Li Z,Wang X
Fri Jul 01 00:00:00 EDT 2022
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
International immunopharmacology
Liang R,Yuan Y,Bai Y,Liu X,Chen J,Jiang D,Meng D,Chen G,Li B,Zhou L,Guo W
Thu Sep 01 00:00:00 EDT 2022
PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.
International journal of biological sciences
Chen YG,Liu HX,Hong Y,Dong PZ,Liu SY,Gao YR,Lu D,Li T,Wang DY,Wu DD,Ji XY
Tue Jul 12 00:00:00 EDT 2022
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
European journal of pharmacology
Zhu X,Peng J,Yang L,Guo Y,Wang P,Liu K,Zhu J,Deng S,Liang M
Sat Oct 15 00:00:00 EDT 2022
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
BMC molecular and cell biology
Wang J,Li G,Lin M,Lin S,Wu L
Fri Dec 23 00:00:00 EST 2022
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Journal of cardiovascular translational research
Cheng L,Wang H,Maboh R,Mao G,Wu X,Chen H
Sat Oct 01 00:00:00 EDT 2022
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Transplant immunology
Xu Z,Sun X,Ding B,Zi M,Ma Y
Sat Oct 01 00:00:00 EDT 2022
Injection of YiQiFuMai powder protects against heart failure via inhibiting p38 and ERK1/2 MAPKs activation.
Pharmaceutical biology
Nie Y,Zhang Y,Li Z,Wan M,Li D
Thu Dec 01 00:00:00 EST 2022
Injection of YiQiFuMai powder protects against heart failure via inhibiting p38 and ERK1/2 MAPKs activation.
Pharmaceutical biology
Nie Y,Zhang Y,Li Z,Wan M,Li D
Thu Dec 01 00:00:00 EST 2022
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Journal of ethnopharmacology
He M,Li L,Wei X,Geng D,Jiang H,Xiangxiang G,Zhang Y,Du H
Mon Jan 10 00:00:00 EST 2022
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Cancer communications (London, England)
Dai W,Xiang W,Han L,Yuan Z,Wang R,Ma Y,Yang Y,Cai S,Xu Y,Mo S,Li Q,Cai G
Thu Sep 01 00:00:00 EDT 2022
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
European journal of pharmacology
Shu J,Hu L,Wu Y,Chen L,Huang K,Wang Z,Liang M
Tue Mar 15 00:00:00 EDT 2022
Overexpression of NCAPG in ovarian cancer is associated with ovarian cancer proliferation and apoptosis via p38 MAPK signaling pathway.
Journal of ovarian research
Yu H,Zou D,Ni N,Zhang S,Zhang Q,Yang L
Fri Aug 19 00:00:00 EDT 2022
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Frontiers in pharmacology
Shi L,Zhao Y,Feng C,Miao F,Dong L,Wang T,Stalin A,Zhang J,Tu J,Liu K,Sun W,Wu J
Wed Sep 07 00:00:00 EDT 2022
GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
iScience
Cao C,Zhou Y,Zhang Y,Ma Y,Du S,Fan L,Niu R,Zhang Y,He M
Fri Jul 15 00:00:00 EDT 2022
Protective Effects of Herba Houttuyniae Aqueous Extract against OVA-Induced Airway Hyperresponsiveness and Inflammation in Asthmatic Mice.
Evidence-based complementary and alternative medicine : eCAM
Yang Y,Lai Q,Wang C,Zhou G
Tue Nov 22 00:00:00 EST 2022
Mapk14 is a Prognostic Biomarker and Correlates with the Clinicopathological Features and Immune Infiltration of Colorectal Cancer.
Frontiers in cell and developmental biology
Wang D,Peng L,Hua L,Li J,Liu Y,Zhou Y
Wed Feb 16 00:00:00 EST 2022
Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts.
Bioengineered
Ren C,Xu Y,Liu H,Wang Z,Ma T,Li Z,Sun L,Huang Q,Zhang K,Zhang C,Cui Y,Wang Q,Lu Y
Tue Mar 01 00:00:00 EST 2022
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
International journal of molecular sciences
Xu Z,Hao X,Li M,Luo H
Sun Aug 28 00:00:00 EDT 2022
Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.
Andrology
Liu K,Sun T,Luan Y,Chen Y,Song J,Ling L,Yuan P,Li R,Cui K,Ruan Y,Lan R,Wang T,Wang S,Liu J,Rao K
Tue Feb 01 00:00:00 EST 2022
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Mediators of inflammation
Wang G,Ma L,Wang B,Gao F,Li J,Cai H,Wang J,Zhang T,Guo H,Xie P,Li Y
Wed Sep 07 00:00:00 EDT 2022
Electroacupuncture attenuates chronic salpingitis transforming growth factor-β1/p38 mitogen-activated protein kinase signaling pathway.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Xijiao HU,Yinglong C,Huanan K,Shuoxi LI,Yawen W,Jinzhe L,Yiming S,Li L
Sat Oct 01 00:00:00 EDT 2022
Acacetin attenuates Streptococcus suis virulence by simultaneously targeting suilysin and inflammation.
Microbial pathogenesis
Xie S,Zhang Y,Xu L,Li S,Shen X,Li L,Deng X,Zhou Y
Sat Jan 01 00:00:00 EST 2022
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Journal of agricultural and food chemistry
Zhang M,Zhang J,Wang C,Yan JK,Yi J,Ning J,Huo XK,Yu ZL,Zhang BJ,Sun CP,Ma XC
Wed Dec 07 00:00:00 EST 2022
Hypothermic oxygenated perfusion combined with TJ-M2010-5 alleviates hepatic ischemia-reperfusion injury in donation after circulatory death.
International immunopharmacology
Zhou W,Peng S,Du P,Zhou P,Xue C,Ye Q
Fri Apr 01 00:00:00 EDT 2022
Losartan attenuates sepsis-induced cardiomyopathy by regulating macrophage polarization via TLR4-mediated NF-κB and MAPK signaling.
Pharmacological research
Chen XS,Wang SH,Liu CY,Gao YL,Meng XL,Wei W,Shou ST,Liu YC,Chai YF
Tue Nov 01 00:00:00 EDT 2022
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang T,He X,Zhao Z,Zhang X,Wang T,Jia L
Tue Nov 01 00:00:00 EDT 2022
Immune-enhancing effects of postbiotic produced by Bacillus velezensis Kh2-2 isolated from Korea Foods.
Food research international (Ottawa, Ont.)
Mi XJ,Tran THM,Park HR,Xu XY,Subramaniyam S,Choi HS,Kim J,Koh SC,Kim YJ
Tue Feb 01 00:00:00 EST 2022
The Immune-Enhancing Properties of Hwanglyeonhaedok-Tang-Mediated Biosynthesized Gold Nanoparticles in Macrophages and Splenocytes.
International journal of nanomedicine
Mi XJ,Xu XY,Choi HS,Kim H,Cho IH,Yi TH,Kim YJ
Tue Feb 08 00:00:00 EST 2022
Endoglin Modulates TGFβR2 Induced VEGF and Proinflammatory Cytokine Axis Mediated Angiogenesis in Prolonged DEHP-Exposed Breast Cancer Cells.
Biomedicines
Jadhao M,Chen CL,Liu W,Deshmukh D,Liao WT,Chen JY,Urade R,Tsai EM,Hsu SK,Wang LF,Chiu CC
Thu Feb 10 00:00:00 EST 2022
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Archives of biochemistry and biophysics
Ji R,Jia FY,Chen X,Wang ZH,Jin WY,Yang J
Sat Jan 15 00:00:00 EST 2022
HIV-1 Tat Protein-Mediated Inflammatory Response Inhibits the Erythroid Hematopoietic Support Function of Bone Marrow Mesenchymal Stem Cells.
AIDS research and human retroviruses
Wang X,Chen M,Ma S,Ding Y,Zhou C,Yuan Y
Thu Sep 01 00:00:00 EDT 2022
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
World journal of gastroenterology
Zhang JJ,Cao CX,Wan LL,Zhang W,Liu ZJ,Wang JL,Guo Q,Tang H
Sat May 07 00:00:00 EDT 2022
Gamma synuclein promotes cancer metastasis through the MKK3/6-p38MAPK cascade.
International journal of biological sciences
Liu J,Shao T,Zhang J,Liu Q,Hua H,Zhang H,Wang J,Luo T,Shi YE,Jiang Y
Thu Jun 02 00:00:00 EDT 2022
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Phytotherapy research : PTR
Han X,Zhang J,Zhou L,Wei J,Tu Y,Shi Q,Zhang Y,Ren J,Wang Y,Ying H,Liang G
Wed Jun 01 00:00:00 EDT 2022
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Journal of veterinary research
Deng CY,Zhu TT,Lian S,Wang JF,Wu R,Zheng JS
Tue Mar 01 00:00:00 EST 2022
Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix.
Journal of ethnopharmacology
Song S,Qiu R,Jin X,Zhou Z,Yan J,Ou Q,Liu X,Li W,Mao Y,Yao W,Lu T
Wed Apr 06 00:00:00 EDT 2022
Kukoamine A inhibits C-C motif chemokine receptor 5 to attenuate lipopolysaccharide-induced lung injury.
Drug development research
Liu X,Wang M,Song Y,Zhang C,Jiang Y,Li W,Xu B,Jiang Z
Thu Sep 01 00:00:00 EDT 2022
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Frontiers in cardiovascular medicine
Rui H,Zhao F,Yuhua L,Hong J
Tue Mar 21 00:00:00 EDT 2023
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Frontiers in pharmacology
Wu Y,Chen M,Chen Z,Shu J,Zhang L,Hu J,Yu H,Huang K,Liang M
Sun Jul 31 00:00:00 EDT 2022
SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.
Nature communications
Yan L,Zhang T,Wang K,Chen Z,Yang Y,Shan B,Sun Q,Zhang M,Zhang Y,Zhong Y,Liu N,Gu J,Xu D
Tue Nov 22 00:00:00 EST 2022
Neurotoxicity and gene expression alterations in zebrafish larvae in response to manganese exposure.
The Science of the total environment
Xu Y,Peng T,Xiang Y,Liao G,Zou F,Meng X
Wed Jun 15 00:00:00 EDT 2022
Fine particulate matter induces endoplasmic reticulum stress-mediated apoptosis in human SH-SY5Y cells.
Neurotoxicology
Zhang M,Wang Y,Wong RMS,Yung KKL,Li R
Sat Jan 01 00:00:00 EST 2022
Resveratrol reduces p38 mitogen-activated protein kinase phosphorylation by activating Sirtuin 1 to alleviate cognitive dysfunction after traumatic brain injury in mice.
Neuroreport
Zhao XY,Yu D,Shi X,Hou S,Teng D
Wed Aug 03 00:00:00 EDT 2022
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Journal of clinical laboratory analysis
Li Z,Xu Q,Huangfu N,Chen X,Zhu J
Sat Jan 01 00:00:00 EST 2022
TSH-TSHR axis promotes tumor immune evasion.
Journal for immunotherapy of cancer
Wu Z,Xi Z,Xiao Y,Zhao X,Li J,Feng N,Hu L,Zheng R,Zhang N,Wang S,Huang T
Sat Jan 01 00:00:00 EST 2022
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Phytotherapy research : PTR
Zhu C,Tian M,Liu N,Ma L,Lan X,Yang J,Du J,Ma H,Li Y,Zheng P,Yu J,Peng X
Thu Sep 01 00:00:00 EDT 2022
Mechanism of HSP90 Inhibitor in the Treatment of DSS-induced Colitis in Mice by Inhibiting MAPK Pathway and Synergistic Effect of Compound Sophora Decoction.
Current pharmaceutical design
Yuan Y,Wu H,Shuai B,Liu C,Zhu F,Gao F,Wei C,Fan H
Fri Jan 06 00:00:00 EST 2023
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Bioorganic chemistry
Gong X,He Y,Yang D,Yang S,Li J,Zhao H,Chen Q,Ren Q,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Study on the Potential Mechanism of Semen Strychni against Myasthenia Gravis Based on Network Pharmacology and Molecular Docking with Experimental Verification.
Evidence-based complementary and alternative medicine : eCAM
Fang P,Yu C,Liu J,Deng G,Zhang M
Wed Oct 12 00:00:00 EDT 2022
Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liao W,Liu W,Yan Y,Li L,Tong J,Huang Y,Guo S,Jiang W,Fu S
Thu Sep 01 00:00:00 EDT 2022
Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression.
Apoptosis : an international journal on programmed cell death
Xiao Q,Liu Y,Zhang X,Liu Z,Xiao J,Ye Q,Fu B
Thu Dec 01 00:00:00 EST 2022
CPSF1 mediates retinal vascular dysfunction in diabetes mellitus via the MAPK/ERK pathway.
Archives of physiology and biochemistry
Zhang J,Zhang X,Zou Y,Han F
Wed Jun 01 00:00:00 EDT 2022
Phycocyanin inhibits Helicobacter pylori-induced hyper-proliferation in AGS cells via activation of the ROS/MAPK signaling pathway.
Annals of translational medicine
Bi Y,Wu D,Wu X,Wang F,Yu H,Liu P,Cui G,Chen Z
Tue Feb 01 00:00:00 EST 2022
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders.
Journal of hazardous materials
Zhao T,Tang X,Li D,Zhao J,Zhou R,Shu F,Jia W,Fu W,Xia H,Liu G
Tue Feb 15 00:00:00 EST 2022
Effect of propiconazole on neutrophil extracellular traps formation: Assessing the role of autophagy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ma Y,Li S,Ye S,Hu D,Luo S,Wei L,Xiao F
Sat Oct 01 00:00:00 EDT 2022
Effects of Uremic Clearance Granules on p38 MAPK/NF-κB Signaling Pathway, Microbial and Metabolic Profiles in End-Stage Renal Disease Rats Receiving Peritoneal Dialysis.
Drug design, development and therapy
Li X,Zheng J,Wang J,Tang X,Zhang F,Liu S,Liao Y,Chen X,Xie W,Tang Y
Thu Aug 11 00:00:00 EDT 2022
The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway.
Acta pharmacologica Sinica
Su XL,Wang SH,Komal S,Cui LG,Ni RC,Zhang LR,Han SN
Thu Sep 01 00:00:00 EDT 2022
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling.
Fish & shellfish immunology
Li S,Wang Y,Yu D,Zhang Y,Wang X,Shi M,Xiao Y,Li X,Xiao H,Chen L,Xiong X
Sat Oct 01 00:00:00 EDT 2022
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Journal of neuroinflammation
Gao C,Jia W,Xu W,Wu Q,Wu J
Sat May 22 00:00:00 EDT 2021
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas.
BMC endocrine disorders
Wang S,Wang A,Zhang Y,Zhu K,Wang X,Chen Y,Wu J
Tue Nov 23 00:00:00 EST 2021
Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Cell reports
Bai X,Liao Y,Sun F,Xiao X,Fu S
Tue Sep 07 00:00:00 EDT 2021
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Food & function
Bai X,Fu R,Duan Z,Liu Y,Zhu C,Fan D
Wed Apr 07 00:00:00 EDT 2021
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Phytochemistry
Song Z,Gao C,Jiang Q,Xu J,Xiong L,Liu K,Sun D,Li H,Chen L
Wed Dec 01 00:00:00 EST 2021
Simvastatin Enhances the Chondrogenesis But Not the Osteogenesis of Adipose-Derived Stem Cells in a Hyaluronan Microenvironment.
Biomedicines
Wu SC,Chang CH,Chang LH,Wu CW,Chen JW,Chen CH,Lin YS,Chang JK,Ho ML
Mon May 17 00:00:00 EDT 2021
Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Adham AN,Abdelfatah S,Naqishbandi AM,Mahmoud N,Efferth T
Fri Jan 01 00:00:00 EST 2021
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
Frontiers in pharmacology
Zhang Y,Qi Z,Wang W,Wang L,Cao F,Zhao L,Fang X
Tue Aug 31 00:00:00 EDT 2021
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Archives of pharmacal research
Zheng X,Liu H,Ma M,Ji J,Zhu F,Sun L
Thu Apr 01 00:00:00 EDT 2021
The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations.
European journal of medicinal chemistry
Xia Z,Huang R,Zhou X,Chai Y,Chen H,Ma L,Yu Q,Li Y,Li W,He Y
Mon Nov 15 00:00:00 EST 2021
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Frontiers in pharmacology
Yong C,Zhang Z,Huang G,Yang Y,Zhu Y,Qian L,Tian F,Liu L,Wu Q,Xu Z,Chen C,Zhao J,Gao K,Zhou E
Wed Dec 15 00:00:00 EST 2021
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jia X,Zhu H,Li G,Lan M,Li X,Huang M,Xu W,Wu S
Sat May 01 00:00:00 EDT 2021
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Journal of ethnopharmacology
Qin MY,Huang SQ,Zou XQ,Zhong XB,Yang YF,Zhang YT,Mi ZC,Zhang YS,Huang ZG
Mon Nov 15 00:00:00 EST 2021
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Journal of ethnopharmacology
Qin MY,Huang SQ,Zou XQ,Zhong XB,Yang YF,Zhang YT,Mi ZC,Zhang YS,Huang ZG
Mon Nov 15 00:00:00 EST 2021
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Nutrition and cancer
Hu Z,Wang H,Fu Y,Ma K,Ma X,Wang J
Wed Sep 08 00:00:00 EDT 2021
Paternal exposure to microcystin-LR triggers developmental neurotoxicity in zebrafish offspring via an epigenetic mechanism involving MAPK pathway.
The Science of the total environment
Zhao S,Xu J,Zhang W,Yan W,Li G
Wed Oct 20 00:00:00 EDT 2021
Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
Cartilage
Shen PC,Chou SH,Lu CC,Huang HT,Chien SH,Huang PJ,Liu ZM,Shih CL,Su SJ,Chen LM,Tien YC
Wed Dec 01 00:00:00 EST 2021
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Food chemistry
Cai J,Li X,Wang X,Jiang C,Shen D,Cui X,Xie K,Ji C,Cao Y
Wed Jun 30 00:00:00 EDT 2021
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
BioMed research international
Dou Q,Tong H,Yang Y,Zhang H,Gan H
Wed Sep 22 00:00:00 EDT 2021
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Drug design, development and therapy
Ma L,Wu F,Shao Q,Chen G,Xu L,Lu F
Mon Jan 10 00:00:00 EST 2022
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Frontiers in oncology
Zhao J,Jiang Y,Chen L,Ma Y,Zhang H,Zhou J,Li H,Jing Z
Fri Aug 20 00:00:00 EDT 2021
The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson's disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway.
Metabolic brain disease
Kambey PA,Chengcheng M,Xiaoxiao G,Abdulrahman AA,Kanwore K,Nadeem I,Jiao W,Gao D
Thu Apr 01 00:00:00 EDT 2021
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
IUBMB life
Wang L,Chen X,Wang L,Wang S,Li W,Liu Y,Zhang J
Mon Nov 01 00:00:00 EDT 2021
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages.
Journal of agricultural and food chemistry
Zhou X,Ahn DU,Xia M,Zeng Q,Li X,Cai Z
Wed Aug 11 00:00:00 EDT 2021
MCLR induces dysregulation of calcium homeostasis and endoplasmic reticulum stress resulting in apoptosis in Sertoli cells.
Chemosphere
Zhao S,Yuan C,Tuo X,Zhou C,Zhao Q,Shen T
Fri Jan 01 00:00:00 EST 2021
Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.
Frontiers in pharmacology
Li T,Jiang G,Hu X,Yang D,Tan T,Gao Z,Chen Z,Xiang C,Li S,Ouyang Z,Guo X
Tue Dec 07 00:00:00 EST 2021
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Journal of medicinal chemistry
Zhou Z,Li Y,Ma X,Cao B,Peng T,Sheng Y,Peng H,Li R,Cao Y,Xi R,Li F,Wang M,Sun H,Zhang G,Zhang H,Hu K,Xiao W,Wang F
Thu Jun 10 00:00:00 EDT 2021
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
Journal of cellular and molecular medicine
Liu Y,Nie X,Zhu J,Wang T,Li Y,Wang Q,Sun Z
Fri Jan 01 00:00:00 EST 2021
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
American journal of physiology. Gastrointestinal and liver physiology
Hong Y,Ren X,Liu W,Sun K,Chen B,Liu B,Yu X,Chen Q,Qian Q,Xie X,Jiang C
Fri Oct 01 00:00:00 EDT 2021
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
ACS chemical neuroscience
Sun Y,Zhang H,Wu Z,Yu X,Yin Y,Qian S,Wang Z,Huang J,Wang W,Liu T,Xue W,Chen G
Wed Sep 15 00:00:00 EDT 2021
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Journal of neuroinflammation
Wang C,Xu T,Lachance BB,Zhong X,Shen G,Xu T,Tang C,Jia X
Thu Feb 18 00:00:00 EST 2021
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Mediators of inflammation
Wan Y,Song M,Xie X,Chen Z,Gao Z,Wu X,Huang R,Chen M
Thu Mar 31 00:00:00 EDT 2022
Sympathetic activity is correlated with satellite cell aging and myogenesis via β2-adrenoceptor.
Stem cell research & therapy
Yuan S,Zheng S,Zheng K,Gao Y,Chen M,Li Y,Bai X
Thu Sep 16 00:00:00 EDT 2021
Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells.
Food & function
Yang JJ,Wang YH,Yin J,Leng H,Shen SD
Mon Aug 02 00:00:00 EDT 2021
The effects of Omarigliptin on promoting osteoblastic differentiation.
Bioengineered
Liao F,Hu X,Chen R
Wed Dec 01 00:00:00 EST 2021
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
International immunopharmacology
Wang X,Chen S,Zhao L,Shi X
Sun Aug 01 00:00:00 EDT 2021
RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
DNA and cell biology
Zhou M,Chen X,Bai H,Sun Y,Zhang Z,Li S,Wang X,Zeng M
Mon Nov 01 00:00:00 EDT 2021
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Journal of hazardous materials
Lai X,Wang M,Zhu Y,Feng X,Liang H,Wu J,Nie L,Li L,Shao L
Sat May 15 00:00:00 EDT 2021
Long noncoding RNA AFAP1-AS1 promotes tumor progression and invasion by regulating the miR-2110/Sp1 axis in triple-negative breast cancer.
Cell death & disease
Zhang X,Li F,Zhou Y,Mao F,Lin Y,Shen S,Li Y,Zhang S,Sun Q
Fri Jun 18 00:00:00 EDT 2021
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Cai C,Hu W,Zhang Y,Hu X,Yang S,Qiu H,Wang R,Ma M,Qiu Y,Chu T
Tue Nov 23 00:00:00 EST 2021
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Pulmonary pharmacology & therapeutics
Luo Y,Chen H,Huang R,Wu Q,Li Y,He Y
Sun Aug 01 00:00:00 EDT 2021
The effects of mTOR or Vps34-mediated autophagy on methylmercury-induced neuronal apoptosis in rat cerebral cortex.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ni L,Wei Y,Pan J,Li X,Xu B,Deng Y,Yang T,Liu W
Wed Sep 01 00:00:00 EDT 2021
The miR-223-3p/MAP1B axis aggravates TGF-β-induced proliferation and migration of BPH-1 cells.
Cellular signalling
Wang Z,Zhang Y,Zhao C,Li Y,Hu X,Wu L,Chen M,Tong S
Sun Aug 01 00:00:00 EDT 2021
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Frontiers in oncology
Nisar MA,Zheng Q,Saleem MZ,Ahmmed B,Ramzan MN,Ud Din SR,Tahir N,Liu S,Yan Q
Tue Jun 01 00:00:00 EDT 2021
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
European journal of medicinal chemistry
Tang JJ,Wang MR,Dong S,Huang LF,He QR,Gao JM
Mon Nov 15 00:00:00 EST 2021
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Journal of ethnopharmacology
Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F
Tue Aug 10 00:00:00 EDT 2021
Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
International immunopharmacology
Tao Y,Sun Y,Wu B,Xu D,Yang J,Gu L,Du C
Sat May 01 00:00:00 EDT 2021
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Bone & joint research
Liu ZM,Lu CC,Shen PC,Chou SH,Shih CL,Chen JC,Tien YC
Sun Aug 01 00:00:00 EDT 2021
Bioactive constituents of Mosla chinensis-cv. Jiangxiangru ameliorate inflammation through MAPK signaling pathways and modify intestinal microbiota in DSS-induced colitis mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang X,Cheng K,Liu Z,Sun Y,Zhou L,Xu M,Dai X,Xiong Y,Zhang H
Wed Dec 01 00:00:00 EST 2021
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Biochemical and biophysical research communications
Wu HH,Meng TT,Chen JM,Meng FL,Wang SY,Liu RH,Chen JN,Ning B,Li Y,Su GH
Fri May 14 00:00:00 EDT 2021
KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway.
BMC cancer
Ma D,Pan Z,Chang Q,Zhang JJ,Liu X,Hua N,Li GH
Thu Apr 08 00:00:00 EDT 2021
Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn's Disease.
Journal of Crohn's & colitis
Gong W,Zheng T,Guo K,Fang M,Xie H,Li W,Tang Q,Hong Z,Ren H,Gu G,Wang G,Wu X,Zhao Y,Ren J
Wed Dec 02 00:00:00 EST 2020
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Frontiers in cell and developmental biology
Lv F,Li N,Kong M,Wu J,Fan Z,Miao D,Xu Y,Ye Q,Wang Y
Mon Sep 28 00:00:00 EDT 2020
Sodium acetate alleviated high-carbohydrate induced intestinal inflammation by suppressing MAPK and NF-κB signaling pathways in Nile tilapia (Oreochromis niloticus).
Fish & shellfish immunology
Li M,Hu FC,Qiao F,Du ZY,Zhang ML
Sun Mar 01 00:00:00 EST 2020
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Journal of agricultural and food chemistry
Ren C,Wang Y,Lin X,Song H,Zhou Q,Xu W,Shi K,Chen J,Song J,Chen F,Zhang S,Guan W
Wed Apr 08 00:00:00 EDT 2020
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy.
Experimental cell research
Song S,Qiu D,Wang Y,Wei J,Wu H,Wu M,Wang S,Zhou X,Shi Y,Duan H
Sun Mar 15 00:00:00 EDT 2020
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Oxidative medicine and cellular longevity
Zhou X,Liu Z,Ying K,Wang H,Liu P,Ji X,Chi T,Zou L,Wang S,He Z
Wed Jan 27 00:00:00 EST 2021
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Journal of burn care & research : official publication of the American Burn Association
Niu X,Lin X,Chen X,Xu S,Huang Z,Tang Q
Mon Nov 30 00:00:00 EST 2020
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hypertensive Rats.
Hypertension (Dallas, Tex. : 1979)
Mukohda M,Mizuno R,Ozaki H
Sat Aug 01 00:00:00 EDT 2020
In vitro and in vivo anti-Listeria effect of Succinoglycan Riclin through regulating MAPK/IL-6 axis and metabolic profiling.
International journal of biological macromolecules
Wu Z,Cheng Y,Yang Y,Gao Y,Sun X,Wang L,Sun Q,Zhang J,Xu X
Fri May 01 00:00:00 EDT 2020
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Journal of experimental & clinical cancer research : CR
Liu JZ,Hu YL,Feng Y,Jiang Y,Guo YB,Liu YF,Chen X,Yang JL,Chen YY,Mao QS,Xue WJ
Tue Jun 30 00:00:00 EDT 2020
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress.
European journal of pharmacology
Yu Z,Yang L,Deng S,Liang M
Thu Oct 15 00:00:00 EDT 2020
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Food research international (Ottawa, Ont.)
Jiang T,Zhou J,Liu W,Tao W,He J,Jin W,Guo H,Yang N,Li Y
Sun Nov 01 00:00:00 EDT 2020
Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells.
Journal of Cancer
Fan Y,Ma K,Jing J,Wang C,Hu Y,Shi Y,Li E,Geng Q
Thu Oct 01 00:00:00 EDT 2020
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Journal of bioscience and bioengineering
Zhu X,Mao Y,Guo M,Yu H,Hao L,Hua Q,Lu Z,Hong M,An F
Sun Nov 01 00:00:00 EDT 2020
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Journal of experimental & clinical cancer research : CR
Hu Z,Long T,Ma Y,Zhu J,Gao L,Zhong Y,Wang X,Wang X,Li Z
Tue May 05 00:00:00 EDT 2020
Inhibiting MAPK14 showed anti-prolactinoma effect.
BMC endocrine disorders
Ding QY,Zhang Y,Ma L,Chen YG,Wu JH,Zhang HF,Wang X
Mon Sep 07 00:00:00 EDT 2020
Inhibiting MAPK14 showed anti-prolactinoma effect.
BMC endocrine disorders
Ding QY,Zhang Y,Ma L,Chen YG,Wu JH,Zhang HF,Wang X
Mon Sep 07 00:00:00 EDT 2020
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Mediators of inflammation
Deng Y,Yang L,Xie Q,Yang F,Li G,Zhang G,Li S,Wu Z,Wang J,Kang X
Mon Feb 01 00:00:00 EST 2021
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
BMC complementary medicine and therapies
Chen JX,Li HY,Li TT,Fu WC,Du X,Liu CH,Zhang W
Wed Jan 29 00:00:00 EST 2020
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Evidence-based complementary and alternative medicine : eCAM
Zheng P,Tian X,Zhang W,Yang Z,Zhou J,Zheng J,Cui H,Tang T,Luo J,Wang Y
Mon Sep 28 00:00:00 EDT 2020
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Neurotoxicity research
Huang M,Guo M,Wang K,Wu K,Li Y,Tian T,Wang Y,Yan W,Zhou Z,Yang H
Wed Apr 01 00:00:00 EDT 2020
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Medical science monitor : international medical journal of experimental and clinical research
Li JM,Yang F,Li J,Yuan WQ,Wang H,Luo YQ
Fri Aug 07 00:00:00 EDT 2020
Changes in inflammatory factors in SV40MES13 mesangial cells after silencing ApoM gene.
International journal of clinical and experimental pathology
Liu J,Zhang Y,Zhang X,Zhang S,Hu Y,Wang L,Gao J,Zhang Y
Wed Jul 15 00:00:00 EDT 2020
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Su C,Wang Q,Luo H,Jiao W,Tang J,Li L,Tian L,Chen X,Liu B,Yu X,Li S,Guo S,Wang W
Wed Jul 01 00:00:00 EDT 2020
Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis.
American journal of translational research
Zong J,Jiang J,Shi P,Liu J,Wang W,Li B,Zhao T,Pan T,Zhang Z,Bi L,Diao Y,Wang S
Mon Sep 28 00:00:00 EDT 2020
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Journal of cellular and molecular medicine
Lu H,Feng Y,Hu Y,Guo Y,Liu Y,Mao Q,Xue W
Wed Jan 01 00:00:00 EST 2020
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Chemico-biological interactions
Jiang YP,Ye RJ,Yang JM,Liu N,Zhang WJ,Ma L,Sun T,Niu JG,Zheng P,Yu JQ
Sun Jan 05 00:00:00 EST 2020
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Chemico-biological interactions
Jiang YP,Ye RJ,Yang JM,Liu N,Zhang WJ,Ma L,Sun T,Niu JG,Zheng P,Yu JQ
Sun Jan 05 00:00:00 EST 2020
Synthesis and biological evaluation of myricetin-pentadienone hybrids as potential anti-inflammatory agents in vitro and in vivo.
Bioorganic chemistry
Liu C,Han X,Yu PJ,Chen LZ,Xue W,Liu XH
Sun Mar 01 00:00:00 EST 2020
DHZCP Modulates Microglial M1/M2 Polarization via the p38 and TLR4/NF-κB Signaling Pathways in LPS-Stimulated Microglial Cells.
Frontiers in pharmacology
Zhou L,Wang D,Qiu X,Zhang W,Gong Z,Wang Y,Xu X
Mon Sep 28 00:00:00 EDT 2020
A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H2O2, and produce large amounts CO for a highly efficient treatment of osteoarthritis.
Biomaterials
Yang G,Fan M,Zhu J,Ling C,Wu L,Zhang X,Zhang M,Li J,Yao Q,Gu Z,Cai X
Thu Oct 01 00:00:00 EDT 2020
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.
Cancer discovery
Prager BC,Vasudevan HN,Dixit D,Bernatchez JA,Wu Q,Wallace LC,Bhargava S,Lee D,King BH,Morton AR,Gimple RC,Pekmezci M,Zhu Z,Siqueira-Neto JL,Wang X,Xie Q,Chen C,Barnett GH,Vogelbaum MA,Mack SC,Chavez L,Perry A,Raleigh DR,Rich JN
Sun Nov 01 00:00:00 EDT 2020
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats.
Evidence-based complementary and alternative medicine : eCAM
Wang X,Guo RZ,Ma L,Ding QY,Meng JH,Chen YG,Wu JH
Mon Sep 28 00:00:00 EDT 2020
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury.
European journal of medicinal chemistry
Pang H,Wang N,Chai J,Wang X,Zhang Y,Bi Z,Wu W,He G
Wed Jul 01 00:00:00 EDT 2020
Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis.
The journal of sexual medicine
Chen Y,Zhou B,Yu Z,Yuan P,Sun T,Gong J,Zhang Y,Wang T,Wang S,Liu K,Liu J
Sat Aug 01 00:00:00 EDT 2020
Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis.
The journal of sexual medicine
Chen Y,Zhou B,Yu Z,Yuan P,Sun T,Gong J,Zhang Y,Wang T,Wang S,Liu K,Liu J
Sat Aug 01 00:00:00 EDT 2020
Corilagin Ameliorates Atherosclerosis in Peripheral Artery Disease via the Toll-Like Receptor-4 Signaling Pathway in vitro and in vivo.
Frontiers in immunology
Li Y,Wang Y,Chen Y,Wang Y,Zhang S,Liu P,Chen Z,Song P,Luo L,Luo Y,Dang Y,Zhao L
Tue Apr 20 00:00:00 EDT 2021
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Molecular medicine reports
Li R,Yang W,Hu X,Zhou D,Huang K,Wang C,Li Y,Liu B
Thu Oct 01 00:00:00 EDT 2020
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
International journal of biological sciences
Lv S,Ju C,Peng J,Liang M,Zhu F,Wang C,Huang K,Cheng M,Zhang F
Mon Nov 02 00:00:00 EST 2020
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Life sciences
Xu K,Liu X,Yin D,Ren G,Zhao Y
Sat Feb 15 00:00:00 EST 2020
Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways.
Frontiers in pharmacology
Gu LF,Ge HT,Zhao L,Wang YJ,Zhang F,Tang HT,Cao ZY,Yu BY,Chai CZ
Mon Sep 28 00:00:00 EDT 2020
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Life sciences
Luo J,Yang C,Luo X,Yang Y,Li J,Song B,Zhao J,Li L
Sat Aug 01 00:00:00 EDT 2020
Isorhamnetin attenuates Streptococcus suis virulence by inhibiting the inflammatory response.
Antonie van Leeuwenhoek
Li G,Wang G,Wang S,Sun M,Wen Z
Sat Feb 01 00:00:00 EST 2020
Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts.
Chinese journal of natural medicines
Zhou D,Yang WK,Zhang YF,Xie JH,Ma L,Yang HD,Li Y,Xie P
Mon Jun 01 00:00:00 EDT 2020
Antioxidants suppress radiation-induced apoptosis via inhibiting MAPK pathway in nasopharyngeal carcinoma cells.
Biochemical and biophysical research communications
Meng DF,Guo LL,Peng LX,Zheng LS,Xie P,Mei Y,Li CZ,Peng XS,Lang YH,Liu ZJ,Wang MD,Xie DH,Shu DT,Hu H,Lin ST,Li HF,Luo FF,Sun R,Huang BJ,Qian CN
Tue Jun 30 00:00:00 EDT 2020
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Pharmacological research
Zhu Y,Zhu C,Yang H,Deng J,Fan D
Fri May 01 00:00:00 EDT 2020
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
BioMed research international
Pei ZW,Guo Y,Zhu HL,Dong M,Zhang Q,Wang F
Tue May 04 00:00:00 EDT 2021
Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794.
Cell proliferation
Lan YL,Chen C,Wang X,Lou JC,Xing JS,Zou S,Hu JL,Lyu W,Zhang B
Wed Jan 01 00:00:00 EST 2020
Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Ren Z,Chen L,Wang Y,Wei X,Zeng S,Zheng Y,Gao C,Liu H
Fri Feb 01 00:00:00 EST 2019
Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Ren Z,Chen L,Wang Y,Wei X,Zeng S,Zheng Y,Gao C,Liu H
Fri Feb 01 00:00:00 EST 2019
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Journal of cellular and molecular medicine
Tian L,Su CP,Wang Q,Wu FJ,Bai R,Zhang HM,Liu JY,Lu WJ,Wang W,Lan F,Guo SZ
Mon Jul 01 00:00:00 EDT 2019
Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension.
Neuroscience bulletin
Sun J,Ren XS,Kang Y,Dai HB,Ding L,Tong N,Zhu GQ,Zhou YB
Fri Feb 01 00:00:00 EST 2019
Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension.
Neuroscience bulletin
Sun J,Ren XS,Kang Y,Dai HB,Ding L,Tong N,Zhu GQ,Zhou YB
Fri Feb 01 00:00:00 EST 2019
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Cancer biology & therapy
Fan Y,Li M,Ma K,Hu Y,Jing J,Shi Y,Li E,Dong D
Mon Jul 06 00:00:00 EDT 2020
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Cancer biology & therapy
Fan Y,Li M,Ma K,Hu Y,Jing J,Shi Y,Li E,Dong D
Mon Jul 06 00:00:00 EDT 2020
PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.
Biochemical and biophysical research communications
Lim V,Zhu H,Diao S,Hu L,Hu J
Tue Jan 08 00:00:00 EST 2019
PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.
Biochemical and biophysical research communications
Lim V,Zhu H,Diao S,Hu L,Hu J
Tue Jan 08 00:00:00 EST 2019
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Oxidative medicine and cellular longevity
Wang G,Xu B,Shi F,Du M,Li Y,Yu T,Chen L
Mon Dec 16 00:00:00 EST 2019
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Molecular immunology
Zhao J,Cao J,Yu L,Ma H
Tue Oct 01 00:00:00 EDT 2019
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
Poultry science
He S,Yu Q,He Y,Hu R,Xia S,He J
Sun Dec 01 00:00:00 EST 2019
PM2.5 upregulates rat mesenteric arteries 5-HT2A receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
Environmental toxicology
Wang R,Cao L,Shen ZX,Cao YX,Yu J
Tue Oct 01 00:00:00 EDT 2019
Catalpol promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the Wnt/β-catenin pathway.
Stem cell research & therapy
Zhu Y,Wang Y,Jia Y,Xu J,Chai Y
Tue Jan 22 00:00:00 EST 2019
Red yeast rice ameliorates high-fat diet-induced atherosclerosis in Apoe-/- mice in association with improved inflammation and altered gut microbiota composition.
Food & function
Dong Y,Cheng H,Liu Y,Xue M,Liang H
Wed Jul 17 00:00:00 EDT 2019
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Stem cell research & therapy
Shi A,Heinayati A,Bao D,Liu H,Ding X,Tong X,Wang L,Wang B,Qin H
Thu Jun 13 00:00:00 EDT 2019
Quercetin reduces Streptococcus suis virulence by inhibiting suilysin activity and inflammation.
International immunopharmacology
Li G,Shen X,Wei Y,Si X,Deng X,Wang J
Mon Apr 01 00:00:00 EDT 2019
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Mediators of inflammation
Liu N,Feng J,Lu X,Yao Z,Liu Q,Lv Y,Han Y,Deng J,Zhou Y
Mon Jan 27 00:00:00 EST 2020
Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma.
Cell death & disease
Zhang C,Huang H,Zhang J,Wu Q,Chen X,Huang T,Li W,Liu Y,Zhang J
Mon Jun 17 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Marine drugs
Lin F,Yang D,Huang Y,Zhao Y,Ye J,Xiao M
Fri Sep 20 00:00:00 EDT 2019
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis.
Evidence-based complementary and alternative medicine : eCAM
Li L,Jiang H,Wei X,Geng D,He M,Du H
Mon Sep 28 00:00:00 EDT 2020
N‑acetyl cysteine inhibits lipopolysaccharide‑induced apoptosis of human umbilical vein endothelial cells via the p38MAPK signaling pathway.
Molecular medicine reports
Xiong T,Zhang Z,Zheng R,Huang J,Guo L
Sun Sep 01 00:00:00 EDT 2019
NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition.
American journal of physiology. Heart and circulatory physiology
Ma Y,Zhang Z,Chen R,Shi R,Zeng P,Chen R,Leng Y,Chen AF
Wed May 01 00:00:00 EDT 2019
Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway.
Experimental cell research
Alam S,Liu Q,Liu S,Liu Y,Zhang Y,Yang X,Liu G,Fan K,Ma J
Sun Sep 15 00:00:00 EDT 2019
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Experimental cell research
Wu X,Chen L,Zeb F,Huang Y,An J,Ren J,Yang F,Feng Q
Sun Sep 01 00:00:00 EDT 2019
CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways.
Cell reports
Xu W,Hua H,Chiu YH,Li G,Zhi H,Yu Z,Ren F,Luo Y,Cui W
Tue Oct 29 00:00:00 EDT 2019
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells.
Journal of physiology and biochemistry
Zhang C,Wu Q,Huang H,Chen X,Huang T,Li W,Liu Y,Zhang J
Fri Nov 01 00:00:00 EDT 2019
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Nutrients
Wang L,Huang W,Zhan J
Fri Dec 06 00:00:00 EST 2019
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
ACS omega
Zhou J,Zheng J,Zhang Y,Zheng P,Tang T,Luo JK,Cui HJ,Song RR,Wang Y
Sun Jun 30 00:00:00 EDT 2019
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Food & function
Ren D,Zhao Y,Zheng Q,Alim A,Yang X
Mon Apr 01 00:00:00 EDT 2019
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Journal of experimental & clinical cancer research : CR
Xie C,Zhu J,Wang X,Chen J,Geng S,Wu J,Zhong C,Li X
Mon Jan 28 00:00:00 EST 2019
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhong KL,Lu MY,Liu F,Mei Y,Zhang XJ,Zhang H,Zan J,Sun XO,Tan W
Tue Jan 01 00:00:00 EST 2019
L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Frontiers in molecular neuroscience
Zhou X,Chu X,Xin D,Li T,Bai X,Qiu J,Yuan H,Liu D,Wang D,Wang Z
Thu Oct 01 00:00:00 EDT 2020
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Nature communications
Zheng J,Fan R,Wu H,Yao H,Yan Y,Liu J,Ran L,Sun Z,Yi L,Dang L,Gan P,Zheng P,Yang T,Zhang Y,Tang T,Wang Y
Mon Apr 08 00:00:00 EDT 2019
Association and clinicopathologic significance of p38MAPK-ERK-JNK-CDC25C with polyploid giant cancer cell formation.
Medical oncology (Northwood, London, England)
Liu K,Lu R,Zhao Q,Du J,Li Y,Zheng M,Zhang S
Sat Nov 16 00:00:00 EST 2019
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Journal of cellular physiology
Ding XF,Liang HY,Sun JY,Liu SH,Kan QC,Wang LX,Sun TW
Sun Sep 01 00:00:00 EDT 2019
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Anais da Academia Brasileira de Ciencias
Haiyuan YU,Shen X,Liu D,Hong M,Lu Y
Wed Jan 22 00:00:00 EST 2020
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jiang YP,Yang JM,Ye RJ,Liu N,Zhang WJ,Ma L,Zheng P,Niu JG,Liu P,Yu JQ
Sun Dec 01 00:00:00 EST 2019
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
British journal of pharmacology
Leng YP,Ma YS,Li XG,Chen RF,Zeng PY,Li XH,Qiu CF,Li YP,Zhang Z,Chen AF
Sun Apr 01 00:00:00 EDT 2018
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
British journal of pharmacology
Leng YP,Ma YS,Li XG,Chen RF,Zeng PY,Li XH,Qiu CF,Li YP,Zhang Z,Chen AF
Sun Apr 01 00:00:00 EDT 2018
Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity.
Diabetes
Wang Y,Yan S,Xiao B,Zuo S,Zhang Q,Chen G,Yu Y,Chen D,Liu Q,Liu Y,Shen Y,Yu Y
Sat Sep 01 00:00:00 EDT 2018
Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity.
Diabetes
Wang Y,Yan S,Xiao B,Zuo S,Zhang Q,Chen G,Yu Y,Chen D,Liu Q,Liu Y,Shen Y,Yu Y
Sat Sep 01 00:00:00 EDT 2018
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Free radical biology & medicine
Xiang L,Xu X,Zhang S,Cai D,Dai X
Mon Aug 20 00:00:00 EDT 2018
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Free radical biology & medicine
Xiang L,Xu X,Zhang S,Cai D,Dai X
Mon Aug 20 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure.
Journal of ethnopharmacology
Chen L,Cao Y,Zhang H,Lv D,Zhao Y,Liu Y,Ye G,Chai Y
Tue Jun 12 00:00:00 EDT 2018
Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure.
Journal of ethnopharmacology
Chen L,Cao Y,Zhang H,Lv D,Zhao Y,Liu Y,Ye G,Chai Y
Tue Jun 12 00:00:00 EDT 2018
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Neurochemical research
Li M,Tian X,An R,Yang M,Zhang Q,Xiang F,Liu H,Wang Y,Xu L,Dong Z
Fri Jun 01 00:00:00 EDT 2018
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Neurochemical research
Li M,Tian X,An R,Yang M,Zhang Q,Xiang F,Liu H,Wang Y,Xu L,Dong Z
Fri Jun 01 00:00:00 EDT 2018
PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation.
OncoTargets and therapy
Lv JM,Chen L,Gao Y,Huang H,Pan XW,Liu X,Chen M,Qu FJ,Li L,Wang JK,Cui XG,Xu DF
Mon Mar 21 00:00:00 EDT 2022
PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation.
OncoTargets and therapy
Lv JM,Chen L,Gao Y,Huang H,Pan XW,Liu X,Chen M,Qu FJ,Li L,Wang JK,Cui XG,Xu DF
Mon Mar 21 00:00:00 EDT 2022
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Cellular and molecular neurobiology
Zhao P,Chang RY,Liu N,Wang J,Zhou R,Qi X,Liu Y,Ma L,Niu Y,Sun T,Li YX,He YP,Yu JQ
Thu Mar 01 00:00:00 EST 2018
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Cellular and molecular neurobiology
Zhao P,Chang RY,Liu N,Wang J,Zhou R,Qi X,Liu Y,Ma L,Niu Y,Sun T,Li YX,He YP,Yu JQ
Thu Mar 01 00:00:00 EST 2018
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
American journal of translational research
Chen T,Zhu H,Wang Y,Zhao P,Chen J,Sun J,Zhang X,Zhu G
Wed Sep 30 00:00:00 EDT 2020
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
American journal of translational research
Chen T,Zhu H,Wang Y,Zhao P,Chen J,Sun J,Zhang X,Zhu G
Wed Sep 30 00:00:00 EDT 2020
Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation.
Journal of molecular neuroscience : MN
Huang L,Chen C,Zhang X,Li X,Chen Z,Yang C,Liang X,Zhu G,Xu Z
Mon Jan 01 00:00:00 EST 2018
Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation.
Journal of molecular neuroscience : MN
Huang L,Chen C,Zhang X,Li X,Chen Z,Yang C,Liang X,Zhu G,Xu Z
Mon Jan 01 00:00:00 EST 2018
SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy.
Frontiers in pharmacology
Li Z,Zhang X,Guo Z,Zhong Y,Wang P,Li J,Li Z,Liu P
Wed Sep 30 00:00:00 EDT 2020
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Molecular pharmaceutics
Wu W,Wang S,Liu Q,Shan T,Wang Y
Mon Aug 06 00:00:00 EDT 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhang Y,Sun Y,Peng R,Liu H,He W,Zhang L,Peng H,Zhang Z
Fri Jan 25 00:00:00 EST 2019
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhang Y,Sun Y,Peng R,Liu H,He W,Zhang L,Peng H,Zhang Z
Fri Jan 25 00:00:00 EST 2019
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Journal of neuroinflammation
Liu WT,Lv YJ,Yang RC,Fu JY,Liu L,Wang H,Cao Q,Tan C,Chen HC,Wang XR
Fri Oct 19 00:00:00 EDT 2018
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Journal of neuroinflammation
Liu WT,Lv YJ,Yang RC,Fu JY,Liu L,Wang H,Cao Q,Tan C,Chen HC,Wang XR
Fri Oct 19 00:00:00 EDT 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury.
Molecular pain
Zhao L,Li D,Liu N,Liu L,Zhang Z,Gao C,Kawano H,Zhou FY,Li HP
Tue Dec 11 00:00:00 EST 2018
Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury.
Molecular pain
Zhao L,Li D,Liu N,Liu L,Zhang Z,Gao C,Kawano H,Zhou FY,Li HP
Tue Dec 11 00:00:00 EST 2018
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao B,Liu L,Mao J,Liu K,Fan W,Liu J,Zhang Z,Li Q
Fri Dec 01 00:00:00 EST 2017
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao B,Liu L,Mao J,Liu K,Fan W,Liu J,Zhang Z,Li Q
Fri Dec 01 00:00:00 EST 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Molecular immunology
Hou L,Gu W,Zhu H,Yao W,Wang W,Meng Q
Wed Nov 01 00:00:00 EDT 2017
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Molecular immunology
Hou L,Gu W,Zhu H,Yao W,Wang W,Meng Q
Wed Nov 01 00:00:00 EDT 2017
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
Microbial pathogenesis
Chen L,Lai Y,Dong L,Kang S,Chen X
Fri Dec 01 00:00:00 EST 2017
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
Microbial pathogenesis
Chen L,Lai Y,Dong L,Kang S,Chen X
Fri Dec 01 00:00:00 EST 2017
Protective effect of resveratrol against nigrostriatal pathway injury in striatum via JNK pathway.
Brain research
Li D,Liu N,Zhao L,Tong L,Kawano H,Yan HJ,Li HP
Sun Jan 01 00:00:00 EST 2017
Protective effect of resveratrol against nigrostriatal pathway injury in striatum via JNK pathway.
Brain research
Li D,Liu N,Zhao L,Tong L,Kawano H,Yan HJ,Li HP
Sun Jan 01 00:00:00 EST 2017
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Oncotarget
Fan L,Cao X,Yan H,Wang Q,Tian X,Zhang L,He X,Borjihan G
Tue Jul 18 00:00:00 EDT 2017
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Oncotarget
Fan L,Cao X,Yan H,Wang Q,Tian X,Zhang L,He X,Borjihan G
Tue Jul 18 00:00:00 EDT 2017
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
International immunopharmacology
Peng Z,Gong X,Yang Y,Huang L,Zhang Q,Zhang P,Wan R,Zhang B
Wed Nov 01 00:00:00 EDT 2017
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Scientific reports
Xu S,Niu P,Chen K,Xia Y,Yu Q,Liu N,Li J,Li S,Wu L,Feng J,Wang W,Lu X,Liu T,Wang F,Dai W,Fan X,Mo W,Xu L,Guo C
Thu Nov 09 00:00:00 EST 2017
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Scientific reports
Xu S,Niu P,Chen K,Xia Y,Yu Q,Liu N,Li J,Li S,Wu L,Feng J,Wang W,Lu X,Liu T,Wang F,Dai W,Fan X,Mo W,Xu L,Guo C
Thu Nov 09 00:00:00 EST 2017
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Inflammation
Tu J,Li W,Zhang Y,Wu X,Song Y,Kang L,Liu W,Wang K,Li S,Hua W,Yang C
Thu Jun 01 00:00:00 EDT 2017
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Drug design, development and therapy
Feng J,Zhang Q,Mo W,Wu L,Li S,Li J,Liu T,Xu S,Fan X,Guo C
Thu Apr 26 00:00:00 EDT 2018
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Drug design, development and therapy
Feng J,Zhang Q,Mo W,Wu L,Li S,Li J,Liu T,Xu S,Fan X,Guo C
Thu Apr 26 00:00:00 EDT 2018
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Scientific reports
Tang H,Yao X,Yao C,Zhao X,Zuo H,Li Z
Tue Aug 08 00:00:00 EDT 2017
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Scientific reports
Tang H,Yao X,Yao C,Zhao X,Zuo H,Li Z
Tue Aug 08 00:00:00 EDT 2017
IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells.
Cell death discovery
Wu X,Song Y,Liu W,Wang K,Gao Y,Li S,Duan Z,Shao Z,Yang S,Yang C
Thu Oct 01 00:00:00 EDT 2020
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 EDT 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 EDT 2017
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo.
Journal of neuroinflammation
Li D,Liu N,Zhao HH,Zhang X,Kawano H,Liu L,Zhao L,Li HP
Wed Mar 29 00:00:00 EDT 2017
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo.
Journal of neuroinflammation
Li D,Liu N,Zhao HH,Zhang X,Kawano H,Liu L,Zhao L,Li HP
Wed Mar 29 00:00:00 EDT 2017
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
International journal of biological macromolecules
Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q
Tue Nov 01 00:00:00 EDT 2016
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
International journal of biological macromolecules
Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q
Tue Nov 01 00:00:00 EDT 2016
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mao Y,Wang J,Yu F,Li Z,Li H,Guo C,Fan X
Thu Dec 01 00:00:00 EST 2016
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mao Y,Wang J,Yu F,Li Z,Li H,Guo C,Fan X
Thu Dec 01 00:00:00 EST 2016
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
American journal of cancer research
Li D,Qu C,Ning Z,Wang H,Zang K,Zhuang L,Chen L,Wang P,Meng Z
Thu Oct 01 00:00:00 EDT 2020
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
American journal of cancer research
Li D,Qu C,Ning Z,Wang H,Zang K,Zhuang L,Chen L,Wang P,Meng Z
Thu Oct 01 00:00:00 EDT 2020
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Journal of agricultural and food chemistry
Liu HZ,Tao YX,Luo P,Deng CM,Gu YP,Yang L,Zhong JP
Wed Jul 20 00:00:00 EDT 2016
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Journal of agricultural and food chemistry
Liu HZ,Tao YX,Luo P,Deng CM,Gu YP,Yang L,Zhong JP
Wed Jul 20 00:00:00 EDT 2016
The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.
Cancer biology & therapy
Jin X,Mo Q,Zhang Y,Gao Y,Wu Y,Li J,Hao X,Ma D,Gao Q,Chen P
Tue May 03 00:00:00 EDT 2016
The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.
Cancer biology & therapy
Jin X,Mo Q,Zhang Y,Gao Y,Wu Y,Li J,Hao X,Ma D,Gao Q,Chen P
Tue May 03 00:00:00 EDT 2016
Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3.
Toxicology letters
Gao Y,Yin Y,Xing X,Zhao Z,Lu Y,Sun Y,Zhuang Z,Wang M,Ji W,He Y
Fri Jul 08 00:00:00 EDT 2016
Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3.
Toxicology letters
Gao Y,Yin Y,Xing X,Zhao Z,Lu Y,Sun Y,Zhuang Z,Wang M,Ji W,He Y
Fri Jul 08 00:00:00 EDT 2016
High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy.
Medical science monitor : international medical journal of experimental and clinical research
Zhang W,Sun J,Luo J
Tue May 10 00:00:00 EDT 2016
High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy.
Medical science monitor : international medical journal of experimental and clinical research
Zhang W,Sun J,Luo J
Tue May 10 00:00:00 EDT 2016
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Scientific reports
Li X,Yang J,Liu D,Li J,Niu K,Feng S,Yokota H,Zhang P
Mon Apr 18 00:00:00 EDT 2016
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Scientific reports
Li X,Yang J,Liu D,Li J,Niu K,Feng S,Yokota H,Zhang P
Mon Apr 18 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
Paper-based microreactor array for rapid screening of cell signaling cascades.
Lab on a chip
Huang CH,Lei KF,Tsang NM
Sun Aug 07 00:00:00 EDT 2016
Paper-based microreactor array for rapid screening of cell signaling cascades.
Lab on a chip
Huang CH,Lei KF,Tsang NM
Sun Aug 07 00:00:00 EDT 2016
Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats.
Experimental and therapeutic medicine
DU Q,Hao C,Gou J,Li X,Zou K,He X,Li Z
Fri Apr 01 00:00:00 EDT 2016
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Polychlorinated biphenyl quinone induces endothelial barrier dysregulation by setting the cross talk between VE-cadherin, focal adhesion, and MAPK signaling.
American journal of physiology. Heart and circulatory physiology
Zhang P,Feng S,Bai H,Zeng P,Chen F,Wu C,Peng Y,Zhang Q,Zhang Q,Ye Q,Xue Q,Xu X,Song E,Song Y
Fri May 15 00:00:00 EDT 2015
Polychlorinated biphenyl quinone induces endothelial barrier dysregulation by setting the cross talk between VE-cadherin, focal adhesion, and MAPK signaling.
American journal of physiology. Heart and circulatory physiology
Zhang P,Feng S,Bai H,Zeng P,Chen F,Wu C,Peng Y,Zhang Q,Zhang Q,Ye Q,Xue Q,Xu X,Song E,Song Y
Fri May 15 00:00:00 EDT 2015
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells.
Medical oncology (Northwood, London, England)
Li X,Zou K,Gou J,Du Q,Li D,He X,Li Z
Sun Mar 01 00:00:00 EST 2015
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells.
Medical oncology (Northwood, London, England)
Li X,Zou K,Gou J,Du Q,Li D,He X,Li Z
Sun Mar 01 00:00:00 EST 2015
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Marine drugs
Li J,Wang F,Xia Y,Dai W,Chen K,Li S,Liu T,Zheng Y,Wang J,Lu W,Zhou Y,Yin Q,Lu J,Zhou Y,Guo C
Wed May 27 00:00:00 EDT 2015
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Marine drugs
Li J,Wang F,Xia Y,Dai W,Chen K,Li S,Liu T,Zheng Y,Wang J,Lu W,Zhou Y,Yin Q,Lu J,Zhou Y,Guo C
Wed May 27 00:00:00 EDT 2015
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
PloS one
Gu A,Jie Y,Sun L,Zhao S,E M,You Q
Mon May 23 00:00:00 EDT 2016
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
PloS one
Gu A,Jie Y,Sun L,Zhao S,E M,You Q
Mon May 23 00:00:00 EDT 2016
