Stealth RNAi™ siRNA

Stealth RNAi™ siRNA is the next generation synthetic RNA from Invitrogen. The Stealth RNAi™ siRNA molecules are 25 base-pair double-stranded RNA oligonucleotides with proprietary chemical modifications.

Using Stealth RNAi™ siRNA for your RNAi studies offers the following advantages over traditional siRNA:

· Decreased nonspecific stress responses for clearer results

· High potency for more powerful knockdown of genes

· More stable in both cell culture systems and in vivo

For additional product information, click Stealth RNAi™ siRNA

Stealth RNAi™ siRNA

The BLOCK-iT™ RNAi Designer helps you find gene-specific targets and design 25 nucleotide Stealth RNAi™ siRNA molecules. When you input an accession number or a nucleotide sequence, the designer:

· Checks input sequence for SNPs (if input is a RefSeq accession number)

· BLAST input sequence against databases and selects a number of unique regions

· Uses proprietary design rules* to find 25 nucleotide gene-specific targets for RNAi analysis and reports up to 10 top scoring Stealth RNAi™ siRNA targets

See the Online Help for additional information.

Stealth RNAi™ siRNA Ordering

You can order Stealth RNAi™ siRNA via the RNAi Designer and 5nmoles of 25 nt Stealth RNAi™ siRNA molecules arrive duplexed and desalted. Check ‘Custom Primer Resources’ for other ordering options.

Proprietary design rules*: The proprietary design rules are derived based on statistical analysis of RNA experimental data (e.g. sequence composition, nucleotide content at 5' and 3' ends, thermodynamic properties) collected from multiple validated (functional and non-functional) RNA oligo sets tested on different gene targets.