Design Rank

The BLOCK-iT™ RNAi Designer will generate up to 10 designs per target sequence. Each design is given one of the following five Probability rankings:

Designs with this ranking closely fit the characteristics of the most effective RNAi molecules. They have the greatest likelihood of resulting in >70% knockdown. We recommend testing 2 or 3 designs from this group.

Designs with this ranking fit most of the characteristics of effective RNAi molecules. They are very likely to result in >70% effective knockdown. We recommend testing 3 designs from this group.

Designs with this ranking fit some of the characteristics of effective RNAi molecules. They are likely to result in >70% effective knockdown. We recommend testing at least 3 designs from this group.

Designs with this ranking have fewer of the characteristics of effective RNAi molecules but they are still likely to result in >70% effective knockdown. We recommend testing at least 3 designs from this group.

Designs with this ranking have the fewest characteristics of effective RNAi molecules but many are still likely to result in >70% effective knockdown. We recommend testing at least 3 designs from this group.