Product References
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
International journal of molecular sciences
Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L
11-0032-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to suggest BC as one of the small molecule candidates to stimulate HSPC expansion both in vitro and in vivo when needed in either physiologic or pathologic conditions, but also supports STS1/STS2 as potential therapeutic drug targets for HSPC expansion and hematopoietic injury recovery.
Fri Feb 03 00:00:00 EST 2023
VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Science advances
Hu Z,Xie Y,Lu J,Yang J,Zhang J,Jiang H,Li H,Zhang Y,Wu D,Zeng K,Bai X,Yu X
11-0032-82 was used in Flow Cytometry to reveal a negative feedback loop of type I interferon IFN-I signaling through the Van Gogh-like 2-TRIP-TBK1-OPTN axis and highlight the cross-talk between IFN-I and autophagy in preventing viral infection.
Fri Jun 23 00:00:00 EDT 2023
Macrophage Reprogramming via the Modulation of Unfolded Protein Response with siRNA-Loaded Magnetic Nanoparticles in a TAM-like Experimental Model.
Pharmaceutics
D'Urso A,Oltolina F,Borsotti C,Prat M,Colangelo D,Follenzi A
11-0032-82 was used in Flow cytometry/Cell sorting to provide a novel strategy for the development of new tumor immunotherapies in vivo.
Mon Jun 12 00:00:00 EDT 2023
A combination therapy of bortezomib, CXCR4 inhibitor, and checkpoint inhibitor is effective in cholangiocarcinoma in vivo.
iScience
Li L,Zhou Y,Zhang Y,Hu H,Mao HQ,Selaru FM
11-0032-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to find that the inhibition of CXCR4 allowed bortezomib to sensitize CCA to anti-PD1 treatment, with a significant reduction of tumor burden and long-term overall survival.
Fri Mar 17 00:00:00 EDT 2023
Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy.
Nature communications
Liu X,Zhuang Y,Huang W,Wu Z,Chen Y,Shan Q,Zhang Y,Wu Z,Ding X,Qiu Z,Cui W,Wang Z
11-0032-82 was used in Flow cytometry/Cell sorting to show in an orthotopic pancreatic cancer model in male mice that the hydrogel microsphere vaccine transforms the immunologically cold tumour microenvironment into hot in a safe and efficient manner, thus significantly increasing survival and inhibiting the growth of distant metastases.
Tue Jul 11 00:00:00 EDT 2023
The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.
PLoS biology
Merchak AR,Cahill HJ,Brown LC,Brown RM,Rivet-Noor C,Beiter RM,Slogar ER,Olgun DG,Gaultier A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Wed Feb 01 00:00:00 EST 2023
Sequence-based drug design as a concept in computational drug design.
Nature communications
Chen L,Fan Z,Chang J,Yang R,Hou H,Guo H,Zhang Y,Yang T,Zhou C,Sui Q,Chen Z,Zheng C,Hao X,Zhang K,Cui R,Zhang Z,Ma H,Ding Y,Zhang N,Lu X,Luo X,Jiang H,Zhang S,Zheng M
11-0032-82 was used in Flow cytometry/Cell sorting to show that the sequence-to-drug concept adds a perspective on drug design.
Fri Jul 14 00:00:00 EDT 2023
Meningeal lymphatics regulate radiotherapy efficacy through modulating anti-tumor immunity.
Cell research
Zhou C,Ma L,Xu H,Huo Y,Luo J
11-0032-82 was used in Flow Cytometry to suggest an essential role of the MLV-CLN network in RT-triggered anti-tumor immunity, and highlight the potential of VEGF-C mRNA for brain tumor therapy.
Wed Jun 01 00:00:00 EDT 2022
A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.
Frontiers in immunology
Li H,Hu M,Huang Z,Wang Y,Xu Y,Deng J,Zhu M,Feng W,Xu X
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Tue Jan 31 00:00:00 EST 2023
LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells.
Scientific reports
Xu Y,Cao L,Ji S,Shen W
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Oct 27 00:00:00 EDT 2022
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Repigmentation by combined narrow‑band ultraviolet B/adipose‑derived stem cell transplantation in the mouse model: Role of Nrf2/HO‑1‑mediated Ca2+ homeostasis.
Molecular medicine reports
Bian Y,Yu H,Jin M,Gao X
11-0032-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to explore the underlying mechanisms and improve the understanding of the pathogenesis of vitiligo.
Sat Jan 01 00:00:00 EST 2022
Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart.
The Journal of cell biology
Liu K,Jin H,Tang M,Zhang S,Tian X,Zhang M,Han X,Liu X,Tang J,Pu W,Li Y,He L,Yang Z,Lui KO,Zhou B
11-0032-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to generate new genetic tools to trace endocardial cells and reassessed their potential contribution to hematopoietic cells in the developing heart. Fate-mapping analyses revealed that the endocardium contributed minimally to cardiac macrophages and circulating blood cells.
Mon Jun 06 00:00:00 EDT 2022
Ferroptosis Inducer Improves the Efficacy of Oncolytic Virus-Mediated Cancer Immunotherapy.
Biomedicines
Liu W,Chen H,Zhu Z,Liu Z,Ma C,Lee YJ,Bartlett DL,Guo ZS
11-0032-82 was used in Flow cytometry/Cell sorting to demonstrate that erastin can exert cytotoxicity on cancer cells via ferroptosis, but has little effect on immune activity by itself.
Wed Jun 15 00:00:00 EDT 2022
Maternal regulation of biliary disease in neonates via gut microbial metabolites.
Nature communications
Jee JJ,Yang L,Shivakumar P,Xu PP,Mourya R,Thanekar U,Yu P,Zhu Y,Pan Y,Wang H,Duan X,Ye Y,Wang B,Jin Z,Liu Y,Cao Z,Watanabe-Chailland M,Romick-Rosendale LE,Wagner M,Fei L,Luo Z,Ollberding NJ,Tang ST,Bezerra JA
11-0032-82 was used in Flow Cytometry to study the relationship between microbial metabolites and biliary disease in offspring.
Mon Jan 10 00:00:00 EST 2022
Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress.
Scientific reports
Martín-Hernández D,Gutiérrez IL,González-Prieto M,MacDowell KS,Robledo-Montaña J,Tendilla-Beltrán H,Calleja-Rodríguez N,Bris ÁG,Ulecia-Morón C,Moreno B,Caso JR,García-Bueno B,Rodrigues-Mascarenhas S,Marín-Jiménez I,Leza JC,Menchén L
11-0032-82 was used in Flow Cytometry to show that sub-chronic stress increased sphingosine-1-phosphate (S1P) in the mouse colon, possibly due to a decrease in its degradation enzymes and sphingosine kinase 2 (Sphk2).
Tue Mar 08 00:00:00 EST 2022
Conjugate of ibrutinib with a TLR7 agonist suppresses melanoma progression and enhances antitumor immunity.
International journal of biological sciences
Ren S,Wang X,Jin G
11-0032-82 was used in Flow Cytometry to suggest that ImmunTacs are a reliable and promising strategy for developing small molecule immunogenic anticancer drugs.
Mon Mar 28 00:00:00 EDT 2022
Human gut bacterial metabolism drives Th17 activation and colitis.
Cell host & microbe
Alexander M,Ang QY,Nayak RR,Bustion AE,Sandy M,Zhang B,Upadhyay V,Pollard KS,Lynch SV,Turnbaugh PJ
11-0032-82 was used in Flow cytometry/Cell sorting to support a role for human gut bacterial metabolism in driving Th17-dependent autoimmunity.
Wed Jan 12 00:00:00 EST 2022
Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Zheng W,Feng Y,Zeng Z,Ye M,Wang M,Liu X,Tang P,Shang H,Sun X,Lin X,Wang M,Li Z,Weng Y,Guo W,Vakal S,Chen JF
11-0032-82 was used in Flow Cytometry to suggest that targeting the choroid plexus-adenosine A2A receptor represents a novel therapeutic strategy for multiple sclerosis by controlling immune cell trafficking across the choroid plexus.
Fri Feb 18 00:00:00 EST 2022
Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Zheng W,Feng Y,Zeng Z,Ye M,Wang M,Liu X,Tang P,Shang H,Sun X,Lin X,Wang M,Li Z,Weng Y,Guo W,Vakal S,Chen JF
11-0032-82 was used in Flow Cytometry to suggest that targeting the choroid plexus-adenosine A2A receptor represents a novel therapeutic strategy for multiple sclerosis by controlling immune cell trafficking across the choroid plexus.
Fri Feb 18 00:00:00 EST 2022
Pancreatic tumor eradication via selective Pin1 inhibition in cancer-associated fibroblasts and T lymphocytes engagement.
Nature communications
Liu J,Wang Y,Mu C,Li M,Li K,Li S,Wu W,Du L,Zhang X,Li C,Peng W,Shen J,Liu Y,Yang D,Zhang K,Ning Q,Fu X,Zeng Y,Ni Y,Zhou Z,Liu Y,Hu Y,Zheng X,Wen T,Li Z,Liu Y
11-0032-82 was used in Flow cytometry/Cell sorting to formulate a DNA-barcoded micellular system (DMS) encapsulating the Pin1 inhibitor AG17724.
Mon Jul 25 00:00:00 EDT 2022
Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice.
Nature communications
Chandana M,Anand A,Ghosh S,Das R,Beura S,Jena S,Suryawanshi AR,Padmanaban G,Nagaraj VA
11-0032-82 was used in Flow cytometry/Cell sorting to show heme synthesized in asexual stages promotes cerebral pathogenesis by enhancing hemozoin formation.
Tue Jul 12 00:00:00 EDT 2022
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy.
Acta pharmaceutica Sinica. B
Peng J,Xiao Y,Yang Q,Liu Q,Chen Y,Shi K,Hao Y,Han R,Qian Z
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model.
Journal of cellular physiology
Mardomi A,Limoni SK,Rahbarghazi R,Mohammadi N,Khorashadizadeh M,Ranjbaran H,Nataj HH,Jafari N,Hasani B,Abediankenari S
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2021
Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy.
Cell and tissue research
Ng KE,Delaney PJ,Thenet D,Murtough S,Webb CM,Zaman N,Tsisanova E,Mastroianni G,Walker SLM,Westaby JD,Pennington DJ,Pink R,Kelsell DP,Tinker A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone.
Frontiers in pharmacology
Tello Rubio B,Bugault F,Baudon B,Raynal B,Brûlé S,Morel JD,Saint-Auret S,Blanchard N,Demangel C,Guenin-Macé L
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Tue Oct 05 00:00:00 EDT 2021
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Frontiers in immunology
Saito T,Sako Y,Sato-Kaneko F,Hosoya T,Yao S,Lao FS,Shpigelman J,Messer K,Pu M,Shukla NM,Chan M,Chu PJ,Cottam HB,Hayashi T,Carson DA,Corr M
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice.
Frontiers in microbiology
Yu X,Zhou G,Shao B,Zhou H,Xu C,Yan F,Wang L,Chen G,Li J,Fu X
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed May 26 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.
Cell reports methods
Fitzgerald B,Connolly KA,Cui C,Fagerberg E,Mariuzza DL,Hornick NI,Foster GG,William I,Cheung JF,Joshi NS
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunocytochemistry
Mon Sep 27 00:00:00 EDT 2021
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity.
EBioMedicine
Deng J,Zhang BZ,Chu H,Wang XL,Wang Y,Gong HR,Li R,Yang D,Li C,Dou Y,Gao P,Cai JP,Jin M,Du Q,Chan JF,Kao RY,Yuen KY,Huang JD
11-0032-82 was used in Flow Cytometry to investigate difference of pro-inflammatory responses and subsequent adaptive immune responses between adsA mutant and WT S. aureus strain infection.
Sun Aug 01 00:00:00 EDT 2021
Loss of circadian protection against influenza infection in adult mice exposed to hyperoxia as neonates.
eLife
Issah Y,Naik A,Tang SY,Forrest K,Brooks TG,Lahens N,Theken KN,Mermigos M,Sehgal A,Worthen GS,FitzGerald GA,Sengupta S
11-0032-82 was used in Flow Cytometry to show that neonatal hyperoxia abolishes the clock-mediated time of day protection from influenza A virus in mice, independent of viral burden through host tolerance pathways.
Tue Mar 02 00:00:00 EST 2021
Soft implantable drug delivery device integrated wirelessly with wearable devices to treat fatal seizures.
Science advances
Joo H,Lee Y,Kim J,Yoo JS,Yoo S,Kim S,Arya AK,Kim S,Choi SH,Lu N,Lee HS,Kim S,Lee ST,Kim DH
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.
Cell reports. Medicine
Blake SJ,James J,Ryan FJ,Caparros-Martin J,Eden GL,Tee YC,Salamon JR,Benson SC,Tumes DJ,Sribnaia A,Stevens NE,Finnie JW,Kobayashi H,White DL,Wesselingh SL,O'Gara F,Lynn MA,Lynn DJ
11-0032-82 was used in Flow Cytometry to show that the immunotoxicity induced by the immune agonist antibodies anti-CD40 and anti-CD137 is dependent on the gut microbiota.
Tue Dec 21 00:00:00 EST 2021
A macrophage-T cell coculture model for severe tissue injury-induced T cell death.
STAR protocols
Zhu J,Cao J,Liesz A,Roth S
11-0032-82 was used in Flow Cytometry to present an in vitro model for cell-cell interactions between innate (macrophages) and adaptive (T cells) immune cells.
Fri Dec 17 00:00:00 EST 2021
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens.
The Journal of experimental medicine
Kang L,Zhang X,Ji L,Kou T,Smith SM,Zhao B,Guo X,Pineda-Torra I,Wu L,Hu X
11-0032-82 was used in Flow Cytometry to demonstrate that colonic macrophage-intrinsic RBP-J dynamically orchestrates intestinal immunity against pathogen infections by interfacing with key immune cells of T and innate lymphoid cell lineages.
Mon Apr 06 00:00:00 EDT 2020
Probody Therapeutic Design of 89Zr-CX-072 Promotes Accumulation in PD-L1-Expressing Tumors Compared to Normal Murine Lymphoid Tissue.
Clinical cancer research : an official journal of the American Association for Cancer Research
Giesen D,Broer LN,Lub-de Hooge MN,Popova I,Howng B,Nguyen M,Vasiljeva O,de Vries EGE,Pool M
11-0032-82 was used in Flow Cytometry to enable clinical evaluation of 89Zr-CX-072 whole-body distribution as a tool to support CX-072 drug development (NCT03013491).
Sat Aug 01 00:00:00 EDT 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation.
Experimental and therapeutic medicine
Shao BY,Wang L,Yu Y,Chen L,Gan N,Huang WM
11-0032 was used in Flow cytometry/Cell sorting to investigate the effects of T cells on the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs).
Sun Nov 01 00:00:00 EDT 2020
Loss of mural cell-derived laminin aggravates hemorrhagic brain injury.
Journal of neuroinflammation
Gautam J,Xu L,Nirwane A,Nguyen B,Yao Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Mon Apr 06 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Nature communications
Galvani E,Mundra PA,Valpione S,Garcia-Martinez P,Smith M,Greenall J,Thakur R,Helmink B,Andrews MC,Boon L,Chester C,Gremel G,Hogan K,Mandal A,Zeng K,Banyard A,Ashton G,Cook M,Lorigan P,Wargo JA,Dhomen N,Marais R
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry (Frozen)
Wed Feb 12 00:00:00 EST 2020
Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways.
Frontiers in immunology
Luo Z,Liao T,Zhang Y,Zheng H,Sun Q,Han F,Yang Z,Sun Q
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.
Nature communications
Buqué A,Bloy N,Perez-Lanzón M,Iribarren K,Humeau J,Pol JG,Levesque S,Mondragon L,Yamazaki T,Sato A,Aranda F,Durand S,Boissonnas A,Fucikova J,Senovilla L,Enot D,Hensler M,Kremer M,Stoll G,Hu Y,Massa C,Formenti SC,Seliger B,Elemento O,Spisek R,André F,Zitvogel L,Delaloge S,Kroemer G,Galluzzi L
11-0032 was used in Flow cytometry/Cell sorting to identify NAM as a potential strategy for the prevention and treatment of HR+ BC.
Thu Jul 30 00:00:00 EDT 2020
Short-Term Rapamycin Preconditioning Diminishes Therapeutic Efficacy of Human Adipose-Derived Stem Cells in a Murine Model of Multiple Sclerosis.
Cells
Wise RM,Harrison MAA,Sullivan BN,Al-Ghadban S,Aleman SJ,Vinluan AT,Monaco ER,Donato UM,Pursell IA,Bunnell BA
11-0032 was used in Flow cytometry/Cell sorting to examine the therapeutic potential of short-term Rapamycin-preconditioned adipose-derived stem cells in the encephalomyelitis model.
Wed Sep 30 00:00:00 EDT 2020
Developmental Dysfunction of the Central Nervous System Lymphatics Modulates the Adaptive Neuro-Immune Response in the Perilesional Cortex in a Mouse Model of Traumatic Brain Injury.
Frontiers in immunology
Wojciechowski S,Virenque A,Vihma M,Galbardi B,Rooney EJ,Keuters MH,Antila S,Koistinaho J,Noe FM
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry (Frozen)
Wed May 19 00:00:00 EDT 2021
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.
Cell metabolism
Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD
11-0032 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.
Tue Dec 03 00:00:00 EST 2019
Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland.
Investigative ophthalmology & visual science
Lee HK,Kim KW,Ryu JS,Jeong HJ,Lee SM,Kim MK
11-0032 was used in Flow cytometry/Cell sorting to demonstrate that a unilateral cut of the corneal nerve results in activation of immune cells on the ocular surface and dysregulation of lacrimal secretion bilaterally through the bidirectional neuronal signals.
Wed Jan 02 00:00:00 EST 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Aging
Fang Y,Zhu L,An N,Jiang G,Qian J,Zhao R,Yuan N,Zhang S,Wang J
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Sun Jul 21 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice.
Oncoimmunology
Lévesque S,Le Naour J,Pietrocola F,Paillet J,Kremer M,Castoldi F,Baracco EE,Wang Y,Vacchelli E,Stoll G,Jolly A,De La Grange P,Zitvogel L,Kroemer G,Pol JG
11-0032-82 was used in Immunocytochemistry to point to the possibility of synergistic interactions among distinct classes of anticancer agents.
Sat Oct 14 00:00:00 EDT 2023
Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.
Scientific reports
Palmer BC,Jatana S,Phelan-Dickinson SJ,DeLouise LA
11-0032 was used in Flow cytometry/Cell sorting to show amorphous silicon dioxide nanoparticles have an immunomodulatory effect in a model of allergic contact dermatitis.
Mon Mar 25 00:00:00 EDT 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
Synergistic immunoreaction of acupuncture-like dissolving microneedles containing thymopentin at acupoints in immune-suppressed rats.
Acta pharmaceutica Sinica. B
Zhang Q,Xu C,Lin S,Zhou H,Yao G,Liu H,Wang L,Pan X,Quan G,Wu C
11-0032 was used in Flow cytometry/Cell sorting to investigate whether the dissolving microneedles can be utilised as a self-administered painless replacement for acupuncture and locally released drug molecules can achieve expected therapeutic outcomes.
Tue May 01 00:00:00 EDT 2018
Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance.
Blood advances
Dangi A,Zhang L,Zhang X,Luo X
11-0032 was used in Flow cytometry/Cell sorting to provide a solid foundation for seeking effective therapies for promoting transplantation tolerance in settings of CMV infection.
Tue Mar 27 00:00:00 EDT 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Neonatal adoptive transfer of lymphocytes rescues social behaviour during adolescence in immune-deficient mice.
The European journal of neuroscience
Clark SM,Vaughn CN,Soroka JA,Li X,Tonelli LH
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
High fish oil diet promotes liver inflammation and activates the complement system.
Molecular medicine reports
Jin H,Yan C,Xiao T,Yan N,Xu J,Zhou L,Zhou X,Shao Q,Xia S
11-0032 was used in Flow cytometry/Cell sorting to study the effects of a high fish oil diet in mice, thus revealing induced inflammation and activation of the complement system in the liver.
Tue May 01 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses.
JCI insight
Watanabe K,Luo Y,Da T,Guedan S,Ruella M,Scholler J,Keith B,Young RM,Engels B,Sorsa S,Siurala M,Havunen R,Tähtinen S,Hemminki A,June CH
11-0032 was used in Flow cytometry/Cell sorting to investigate whether combined mesothelin-redirected chimeric antigen receptor T cell therapy with an oncolytic adenovirus expressing TNF-α and IL-2 would improve anti-tumour efficacy.
Thu Apr 05 00:00:00 EDT 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
11-0032 was used in Flow cytometry/Cell sorting to study the role of type 2 innate lymphoid cells in enhancing anti-cancer immunity and controlling metastasis.
Tue Feb 13 00:00:00 EST 2018
Targeting of the Yersinia pestis F1 capsular antigen by innate-like B1b cells mediates a rapid protective response against bubonic plague.
NPJ vaccines
Levy Y,Vagima Y,Tidhar A,Aftalion M,Gur D,Nili U,Chitlaru T,Zauberman A,Mamroud E
Thu Oct 01 00:00:00 EDT 2020
Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peng J,Xiao Y,Li W,Yang Q,Tan L,Jia Y,Qu Y,Qian Z
11-0032 was used in Flow cytometry/Cell sorting to demonstrate that NLG919/IR780 micelles combine PTT, immunotherapy, suppress the tumour margin and distal tumour growth post photothermal therapy.
Tue May 01 00:00:00 EDT 2018
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
11-0032 was used in Flow cytometry/Cell sorting to describe the function of ILC2 in the regulation of lung inflammation by protecting lung endothelial cell from pyroptosis.
Tue Mar 06 00:00:00 EST 2018
CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload.
JACC. Basic to translational science
Patel B,Bansal SS,Ismahil MA,Hamid T,Rokosh G,Mack M,Prabhu SD
11-0032 was used in Flow cytometry/Cell sorting to demonstrate that monocyte-derived C-C chemokine receptor 2 macrophages infiltrate the heart early during pressure overload in mice and blocking this response alleviates cardiac fibrosis..
Sun Apr 01 00:00:00 EDT 2018
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration.
Arteriosclerosis, thrombosis, and vascular biology
Wang L,Wang Y,Zhang C,Li J,Meng Y,Dou M,Noguchi CT,Di L
11-0032-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to examine the potential mechanism by which GSK3 in modulating obesity-induced visceral adipose tissue (VAT) inflammation.
Sat Sep 01 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
11-0032 was used in Flow cytometry/Cell sorting to explore a variety of IL-2 constructs expressed by a tumour-selective oncolytic vaccinia virus, designed to maintain IL-2 in the tumour microenvironment to reduce systemic toxicity.
Thu Nov 08 00:00:00 EST 2018
Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury.
The Journal of experimental medicine
Gadani SP,Smirnov I,Wiltbank AT,Overall CC,Kipnis J
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Wed Feb 01 00:00:00 EST 2017
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.
Genes & development
Soto-Feliciano YM,Bartlebaugh JME,Liu Y,Sánchez-Rivera FJ,Bhutkar A,Weintraub AS,Buenrostro JD,Cheng CS,Regev A,Jacks TE,Young RA,Hemann MT
11-0032 was used in Flow cytometry/Cell sorting to describe the function of the plant homeodomain finger protein 6 in leukaemia and its role in regulating chromatin accessibility to lineage-specific transcription factors.
Mon May 15 00:00:00 EDT 2017
Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells.
Frontiers in immunology
Li M,Wang B,Sun X,Tang Y,Wei X,Ge B,Tang Y,Deng Y,He C,Yuan J,Li X
11-0032 was used in Flow cytometry/Cell sorting to investigate bacterial consortium transplantation as a treatment for IBD, showing an upregulation of intestinal barrier function associated with expansion of IL-17A producing gamma delta T cells.
Wed Nov 20 00:00:00 EST 2019
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
11-0032 was used in Flow cytometry/Cell sorting to show that the adjuvant MTOM causes strong expansion of IL-2(+) T cells and Th1-type response in combination with WH121.
Wed Nov 20 00:00:00 EST 2019
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunocytochemistry
Sun Oct 01 00:00:00 EDT 2017
In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
PLoS pathogens
Marsden MD,Loy BA,Wu X,Ramirez CM,Schrier AJ,Murray D,Shimizu A,Ryckbosch SM,Near KE,Chun TW,Wender PA,Zack JA
11-0032 was used in Flow cytometry/Cell sorting to show that cells latently-infected by HIV exhibit both "kick" and "kill" strategies upon virus reactivation with a bryostatin 1 analogue.
Fri Sep 01 00:00:00 EDT 2017
The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection.
Immunology
Gonçalves AC,Ferreira LS,Manente FA,de Faria CMQG,Polesi MC,de Andrade CR,Zamboni DS,Carlos IZ
Thu Jun 01 00:00:00 EDT 2017
Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis.
Journal of virology
Bardina SV,Brown JA,Michlmayr D,Hoffman KW,Sum J,Pletnev AG,Lira SA,Lim JK
11-0032 was used in Flow cytometry/Cell sorting to point to Ccr7 as a critical host defense restriction factor limiting neuroinflammation during acute viral infection.
Mon May 15 00:00:00 EDT 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
A polysaccharide component from Strongylocentrotus nudus eggs inhibited hepatocellular carcinoma in mice by activating T lymphocytes.
Oncology letters
Zhang M,Liu Y,Li J,Ke M,Yu J,Dou J,Wang H,Zhou C
Wed Mar 01 00:00:00 EST 2017
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice.
Comparative medicine
Bendtsen KM,Hansen CH,Krych L,Buschard K,Farlov H,Hansen AK
11-0032 was used in Flow cytometry/Cell sorting to demonstrate that mucus reduction and subsequent increased host-bacterial contact did not affect overall disease progression in nonobese diabetic mice.
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.
eLife
Lee P,Gund R,Dutta A,Pincha N,Rana I,Ghosh S,Witherden D,Kandyba E,MacLeod A,Kobielak K,Havran WL,Jamora C
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in T-Cell Activation
Mon Dec 04 00:00:00 EST 2017
Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.
Cell death & disease
Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Concanavalin A-Induced Acute Liver Injury in Mice.
Cell medicine
Yoshizumi Y,Yukawa H,Iwaki R,Fujinaka S,Kanou A,Kanou Y,Yamada T,Nakagawa S,Ohara T,Nakagiri K,Ogihara Y,Tsutsui Y,Hayashi Y,Ishigami M,Baba Y,Ishikawa T
11-0032 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effects of adipose tissue-derived stem cells on fulminant hepatic failure.
Sun Jan 08 00:00:00 EST 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Pini M,Touch S,Poirier H,Dalmas E,Niot I,Rouault C,Druart C,Delzenne N,Clément K,André S,Guerre-Millo M
11-0032 was used in Flow cytometry/Cell sorting to reveal a striking resilience of white adipose tissue after a short-term metabolic injury induced by t10,c12-CLA, which relies on alternatively activated M2 macrophage engagement.
Fri Jan 01 00:00:00 EST 2016
Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance.
Journal of immunology (Baltimore, Md. : 1950)
Michlmayr D,Bardina SV,Rodriguez CA,Pletnev AG,Lim JK
11-0032 was used in Flow cytometry/Cell sorting to study how Ccr5 is crucial in directing T cells toward the LGTV-infected brain, as well as in suppressing neutrophil-mediated inflammation within the CNS.
Wed Jun 01 00:00:00 EDT 2016
Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Yang E,Singh BK,Paustian AM,Kambayashi T
11-0032 was used in Flow cytometry/Cell sorting to investigate methods to enhance NK cell function, showing that diacylglycerol kinase ζ is a target for enhancement of NK function.
Mon Aug 01 00:00:00 EDT 2016
Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model.
Molecular medicine reports
Yue Y,Li P,Song N,Li B,Li Z,Guo Y,Zhang W,Wei MQ,Gai Z,Meng H,Wang J,Qin L
11-0032 was used in Flow cytometry/Cell sorting to understand the virological features of enterovirus 71 and the host responses resulting from enterovirus 71 infection.
Sun May 01 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Tue May 03 00:00:00 EDT 2016
CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy.
EBioMedicine
Pourchet A,Fuhrmann SR,Pilones KA,Demaria S,Frey AB,Mulvey M,Mohr I
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy.
EBioMedicine
Pourchet A,Fuhrmann SR,Pilones KA,Demaria S,Frey AB,Mulvey M,Mohr I
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Nature communications
Jiang X,Hu C,Arnovitz S,Bugno J,Yu M,Zuo Z,Chen P,Huang H,Ulrich B,Gurbuxani S,Weng H,Strong J,Wang Y,Li Y,Salat J,Li S,Elkahloun AG,Yang Y,Neilly MB,Larson RA,Le Beau MM,Herold T,Bohlander SK,Liu PP,Zhang J,Li Z,He C,Jin J,Hong S,Chen J
11-0032 was used in Flow cytometry/Cell sorting to investigate the anti-tumourigenic role of miR-22, showing that it has an anti-tumour role in acute myeloid leukaemia.
Tue Apr 26 00:00:00 EDT 2016
Ly6C(hi) Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis.
Cell reports
Möhle L,Mattei D,Heimesaat MM,Bereswill S,Fischer A,Alutis M,French T,Hambardzumyan D,Matzinger P,Dunay IR,Wolf SA
11-0032 was used in Flow cytometry/Cell sorting to detect that treatment of adult mice with antibiotics decreases hippocampal neurogenesis and memory retention.
Tue May 31 00:00:00 EDT 2016
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
The Journal of clinical investigation
Millet A,Martin KR,Bonnefoy F,Saas P,Mocek J,Alkan M,Terrier B,Kerstein A,Tamassia N,Satyanarayanan SK,Ariel A,Ribeil JA,Guillevin L,Cassatella MA,Mueller A,Thieblemont N,Lamprecht P,Mouthon L,Perruche S,Witko-Sarsat V
11-0032 was used in Flow cytometry/Cell sorting to investigate disruption of immune silencing by proteinase 3 on apoptotic cells.
Mon Nov 02 00:00:00 EST 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
11-0032 was used in Flow cytometry/Cell sorting to evaluate the adjuvant properties of cationic liposomes, Adjuplex and in vivo-JetPEI compared to injection of DNA without adjuvant.
Mon May 16 00:00:00 EDT 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
11-0032 was used in Flow cytometry/Cell sorting to show the immunogenicity and protective efficacy of the DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Fri Mar 11 00:00:00 EST 2016
IL-33 Enhances Humoral Immunity Against Chronic HBV Infection Through Activating CD4(+)CXCR5(+) TFH Cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhao PW,Shi X,Li C,Ayana DA,Niu JQ,Feng JY,Wang J,Jiang YF
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Nature communications
Kang YJ,Bang BR,Han KH,Hong L,Shim EJ,Ma J,Lerner RA,Otsuka M
11-0032 was used in Flow cytometry/Cell sorting to determine the involvement of RIPK3 and RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell-mediated immune responses.
Fri Sep 18 00:00:00 EDT 2015
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Nature communications
Kang YJ,Bang BR,Han KH,Hong L,Shim EJ,Ma J,Lerner RA,Otsuka M
11-0032 was used in Flow cytometry/Cell sorting to determine the involvement of RIPK3 and RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell-mediated immune responses.
Fri Sep 18 00:00:00 EDT 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Protection against Mycobacterium tuberculosis infection offered by a new multistage subunit vaccine correlates with increased number of IFN-γ+ IL-2+ CD4+ and IFN-γ+ CD8+ T cells.
PloS one
Wang X,Zhang J,Liang J,Zhang Y,Teng X,Yuan X,Fan X
11-0032 was used in Flow cytometry/Cell sorting to investigate protein subunit vaccinations for control of tuberculosis, showing that a new multistage subunit vaccine increases numbers of T cells and protects against TB.
Wed Mar 09 00:00:00 EST 2016
The Effects of Antigen-Specific IgG1 Antibody for the Pulmonary-Hypertension-Phenotype and B Cells for Inflammation in Mice Exposed to Antigen and Fine Particles from Air Pollution.
PloS one
Park SH,Chen WC,Durmus N,Bleck B,Reibman J,Riemekasten G,Grunig G
11-0032 was used in Flow cytometry/Cell sorting to identify B cells and antigen specific IgG1 as potential therapeutical targets for pulmonary hypertension.
Mon Apr 25 00:00:00 EDT 2016
HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation-Induced Intestinal Injury by Modulating Immunity.
PloS one
Wang H,Sun RT,Li Y,Yang YF,Xiao FJ,Zhang YK,Wang SX,Sun HY,Zhang QW,Wu CT,Wang LS
11-0032 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effect of hepatocyte growth factor-gene-modified MSCs on radiation-induced intestinal injury.
Tue Jan 26 00:00:00 EST 2016
Natural killer cells promote long-term hepatobiliary inflammation in a low-dose rotavirus model of experimental biliary atresia.
PloS one
Squires JE,Shivakumar P,Mourya R,Bessho K,Walters S,Bezerra JA
11-0032 was used in Flow cytometry/Cell sorting to investigate mechanisms of liver injury in a mouse model of Rhesus rotavirus-induced biliary atresia.
Fri Apr 15 00:00:00 EDT 2016
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.
PLoS genetics
Menon MB,Sawada A,Chaturvedi A,Mishra P,Schuster-Gossler K,Galla M,Schambach A,Gossler A,Förster R,Heuser M,Kotlyarov A,Kinoshita M,Gaestel M
11-0032 was used in Flow cytometry/Cell sorting to reveal septins are essential for completion of mammalian cytokinesis in fibroblasts, but dispensable for cytokinesis in cells of the haematopoietic system.
Fri Aug 01 00:00:00 EDT 2014
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene.
PloS one
Park SH,Chen WC,Hoffman C,Marsh LM,West J,Grunig G
11-0032 was used in Flow cytometry/Cell sorting to test the idea that Th2 responses to a mild antigen, together with the expression of a hypomorphic BMPR2 gene, would trigger pulmonary hypertension.
Mon Jul 22 00:00:00 EDT 2013
Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors.
The Journal of biological chemistry
Stehle F,Schulz K,Fahldieck C,Kalich J,Lichtenfels R,Riemann D,Seliger B
11-0032 was used in Flow cytometry/Cell sorting to investigate the reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors.
Fri Jun 07 00:00:00 EDT 2013
Interleukin-15 treatment induces weight loss independent of lymphocytes.
PloS one
Barra NG,Chew MV,Reid S,Ashkar AA
11-0032 was used in Flow cytometry/Cell sorting to determine if lymphocytes, particularly natural killer cells, play a role in Interleukin-15 mediated weight loss.
Tue Nov 27 00:00:00 EST 2012
CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis.
Journal of immunology (Baltimore, Md. : 1950)
Endharti AT,Okuno Y,Shi Z,Misawa N,Toyokuni S,Ito M,Isobe K,Suzuki H
11-0032 was used in Flow cytometry/Cell sorting to investigate the role of CD8(+)CD122(+) regulatory T cells (Tregs) in maintenance of immune homeostasis, showing that CD8(+)CD122(+) Tregs and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis.
Sat Jan 01 00:00:00 EST 2011
Increased incidence of endometrioid tumors caused by aberrations in E-cadherin promoter of mismatch repair-deficient mice.
Carcinogenesis
Kovtun IV,Harris KJ,Jatoi A,Jevremovic D
Published figure using CD3 monoclonal antibody (Product # 11-0032-82) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2011
Localized delivery of interferon-β by Lactobacillus exacerbates experimental colitis.
PloS one
McFarland AP,Savan R,Wagage S,Addison A,Ramakrishnan K,Karwan M,Duong T,Young HA
11-0032 was used in Flow cytometry/Cell sorting to identify a correlation between the loss/down-regulation of IFNAR1 on DCs and exacerbation of colitis.
Fri Feb 18 00:00:00 EST 2011
Attenuated Bordetella pertussis protects against highly pathogenic influenza A viruses by dampening the cytokine storm.
Journal of virology
Li R,Lim A,Phoon MC,Narasaraju T,Ng JK,Poh WP,Sim MK,Chow VT,Locht C,Alonso S
11-0032 was used in Flow cytometry/Cell sorting to indicate that protection against influenza virus-induced severe pneumonitis can be achieved through attenuation of exaggerated cytokine-mediated inflammation.
Thu Jul 01 00:00:00 EDT 2010
The death effector domain protein PEA-15 negatively regulates T-cell receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Pastorino S,Renganathan H,Caliva MJ,Filbert EL,Opoku-Ansah J,Sulzmaier FJ,Gawecka JE,Werlen G,Shaw AS,Ramos JW
11-0032 was used in Flow cytometry/Cell sorting to investigate the physiological function of PEA-15, showing that it negatively regulates T-cell receptor signalling.
Sun Aug 01 00:00:00 EDT 2010
Cross-presentation of disialoganglioside GD3 to natural killer T cells.
The Journal of experimental medicine
Wu DY,Segal NH,Sidobre S,Kronenberg M,Chapman PB
11-0032 was used in Flow cytometry/Cell sorting to demonstrate that immunising mice with the SK-MEL-28 cell line or with syngeneic APCs loaded with GD3 can induce a GD3-reactive natural killer T cell response.
Mon Jul 07 00:00:00 EDT 2003
