Product References
MiR-216a-3p inhibits the proliferation and invasion of fibroblast-like synoviocytes by targeting dual-specificity phosphatase 5.
International journal of rheumatic diseases
Ni R,Liu H,Song G,Fu X,Deng B,Xu Z,Dai S,Huang G
Sat Apr 01 00:00:00 EDT 2023
QSER1 preserves the suppressive status of the pro-apoptotic genes to prevent apoptosis.
Cell death and differentiation
Zhao X,Fang K,Liu X,Yao R,Wang M,Li F,Hao S,He J,Wang Y,Fan M,Huang W,Li Y,Gao C,Lin C,Luo Z
Wed Mar 01 00:00:00 EST 2023
The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair.
Proceedings of the National Academy of Sciences of the United States of America
Li J,Zhao J,Gan X,Wang Y,Jiang D,Chen L,Wang F,Xu J,Pei H,Huang J,Chen X
Tue May 16 00:00:00 EDT 2023
[WITHDRAWN] Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction.
Research square
Tatekoshi Y,Shapiro JS,Liu M,Bianco GM,Tatekoshi A,De Jesus A,Koleini N,Wasserstrom JA,Dillmann WH,Weinberg SE,Ardehali H
Wed Jan 25 00:00:00 EST 2023
Loss-of-function mutations in IQCN cause male infertility in humans and mice owing to total fertilization failure.
Molecular human reproduction
Wang Y,Chen G,Tang Z,Mei X,Lin C,Kang J,Lian J,Lu J,Liu Y,Lan F,Huang W,Zhang D
Fri Jun 30 00:00:00 EDT 2023
Loss-of-function mutations in IQCN cause male infertility in humans and mice owing to total fertilization failure.
Molecular human reproduction
Wang Y,Chen G,Tang Z,Mei X,Lin C,Kang J,Lian J,Lu J,Liu Y,Lan F,Huang W,Zhang D
Fri Jun 30 00:00:00 EDT 2023
Repurposing crizotinib to target RIPK1-dependent cell death.
International immunology
Yu Y,Li M,Fu S,He X,Hu X,Zhu G,Wang J,You X,Mou Y,Ye Z,Wei J,Zha Y
Mon May 08 00:00:00 EDT 2023
Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes.
The Journal of biological chemistry
Wang X,Zhang Y,Lin Q,Zhao K,Zhu D,Hu Y
Wed Feb 01 00:00:00 EST 2023
Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation.
Free radical biology & medicine
Zhang B,Hou Q,Zhang X,Ma Y,Yuan J,Li S,Zhao X,Sun L,Wang H,Zheng H
Wed Feb 01 00:00:00 EST 2023
Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2/GSH/GPX4 axis exacerbates hepatotoxicity.
The Science of the total environment
Liu J,Yang G,Zhang H
Wed Mar 01 00:00:00 EST 2023
Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus.
Cell death discovery
Song C,Zhao J,Hao J,Mi D,Zhang J,Liu Y,Wu S,Gao F,Jiang W
Thu May 04 00:00:00 EDT 2023
Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
Journal of medical virology
Tu W,Liu J,Qian F,Zhu L,Li M,Zheng H,Zhu C
Wed Mar 01 00:00:00 EST 2023
Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.
Diabetes, metabolic syndrome and obesity : targets and therapy
Ni Y,Chen Y,Jiang X,Pu T,Zhang L,Li S,Hu L,Bai B,Hu T,Yu L,Yang Y
Wed Feb 15 00:00:00 EST 2023
Crosstalk between PML and p53 in response to TGF-β1: A new mechanism of cardiac fibroblast activation.
International journal of biological sciences
Huang D,Zhao D,Li M,Chang SY,Xue YD,Xu N,Li SJ,Tang NN,Gong LL,Liu YN,Yu H,Li QS,Li PY,Liu JL,Chen HX,Liu MB,Zhang WY,Zhao XM,Lang XZ,Li ZD,Liu Y,Ma ZY,Li JM,Wang N,Tian H,Cai BZ
Wed Feb 15 00:00:00 EST 2023
DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
The EMBO journal
Taffoni C,Marines J,Chamma H,Guha S,Saccas M,Bouzid A,Valadao AC,Maghe C,Jardine J,Park MK,Polak K,De Martino M,Vanpouille-Box C,Del Rio M,Gongora C,Gavard J,Bidère N,Song MS,Pineau D,Hugnot JP,Kissa K,Fontenille L,Blanchet FP,Vila IK,Laguette N
Mon Apr 03 00:00:00 EDT 2023
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang W,Zuo J,Liu M,Su Y,Guo B,Hou J,Xing Q,Peng Y,Fang L,Cao Y,Shan J,Sun R,Zhao J,Wang J
Sun Jan 01 00:00:00 EST 2023
Resveratrol improves follicular development of PCOS rats via regulating glycolysis pathway and targeting SIRT1.
Systems biology in reproductive medicine
Huo P,Li M,Le J,Zhu C,Yao J,Zhang S
Sat Apr 01 00:00:00 EDT 2023
Specific Residues in the C-Terminal Domain of the Human Metapneumovirus Phosphoprotein Are Indispensable for Formation of Viral Replication Centers and Regulation of the Function of the Viral Polymerase Complex.
Journal of virology
Thompson RE,Edmonds K,Dutch RE
Wed May 31 00:00:00 EDT 2023
Morusinol extracted from Morus alba induces cell cycle arrest and apoptosis via inhibition of DNA damage response in melanoma by CHK1 degradation through the ubiquitin-proteasome pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Guo L,Dong Z,Zhang X,Yang Y,Hu X,Ji Y,Li C,Wan S,Xu J,Liu C,Zhang Y,Liu L,Shi Y,Wu Z,Liu Y,Cui H
Thu Jun 01 00:00:00 EDT 2023
Nucleolar protein treacle ribosome biogenesis factor 1 maintains gastric cancer cell proliferation by regulating R-loop associated DNA replication stress.
Journal of gastroenterology and hepatology
Nie X,Zhao C,Zhang Y,Huang W,Zhou Y,Liu H,Nie Y,Xie K,Jia L
Sat Jul 01 00:00:00 EDT 2023
ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth.
Proceedings of the National Academy of Sciences of the United States of America
Zuo Z,Liu J,Sun Z,Cheng YW,Ewing M,Bugge TH,Finkel T,Leppla SH,Liu S
Tue Jan 03 00:00:00 EST 2023
Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates.
Developmental cell
Fu Y,Jia X,Yuan J,Yang Y,Zhang T,Yu Q,Zhou J,Wang T
Mon Mar 13 00:00:00 EDT 2023
KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.
Cell death & disease
Li J,Yu D,He C,Yu Q,Huo Z,Zhang Y,Zhang S
Sat Jul 01 00:00:00 EDT 2023
Expression and Clinical Significance of TIGIT in Primary Breast Cancer.
International journal of general medicine
Tang L,Sha M,Guo T,Lu H,Qian J,Shao Q,Ye J
Tue Jun 20 00:00:00 EDT 2023
Epitranscriptic regulation of HRAS by N6-methyladenosine drives tumor progression.
Proceedings of the National Academy of Sciences of the United States of America
Pan Y,Gu Y,Liu T,Zhang Q,Yang F,Duan L,Cheng S,Zhu X,Xi Y,Chang X,Ye Q,Gao S
Tue Apr 04 00:00:00 EDT 2023
GLUT4 degradation by GLUTFOURINH® in mice resembles moderate-obese diabetes of human with hyperglycemia and low lipid accumulation.
Biochimica et biophysica acta. Molecular basis of disease
Lee SR,Jeong SH,Mukae M,Jeong KJ,Kwun HJ,Hong EJ
Thu Jun 01 00:00:00 EDT 2023
Effects of early exercise intervention and exercise cessation on neuronal loss and neuroinflammation in a senescence-accelerated mouse prone 8.
Neuroscience letters
Nakanishi K,Norimatsu K,Tani A,Matsuoka T,Matsuzaki R,Kakimoto S,Nojima N,Tachibe Y,Kato Y,Inadome M,Kitazato R,Otsuka S,Takada S,Sumizono M,Sakakima H
Wed Jun 21 00:00:00 EDT 2023
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Cell research
Qiu S,Zhong X,Meng X,Li S,Qian X,Lu H,Cai J,Zhang Y,Wang M,Ye Z,Zhang H,Gao P
Sat Apr 01 00:00:00 EDT 2023
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Nature communications
Wu J,Bu D,Wang H,Shen D,Chong D,Zhang T,Tao W,Zhao M,Zhao Y,Fang L,Li P,Xue B,Li CJ
Fri Mar 24 00:00:00 EDT 2023
TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination.
The Journal of biological chemistry
Chen YY,Ran XH,Ni RZ,Mu D
Mon May 01 00:00:00 EDT 2023
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.
Neural regeneration research
Huang LY,Ma JY,Song JX,Xu JJ,Hong R,Fan HD,Cai H,Wang W,Wang YL,Hu ZL,Shen JG,Qi SH
Mon May 01 00:00:00 EDT 2023
Vitamin D3 and Lactobacillus rhamnosus GG/p40 Synergize to Protect Mice From Colitis by Promoting Vitamin D Receptor Expression and Epithelial Proliferation.
Inflammatory bowel diseases
Chen D,Tang H,Li Y,Yang H,Wang H,Tan B,Qian J
Mon Apr 03 00:00:00 EDT 2023
Anti-inflammatory activity of 2-methoxy-4-vinylphenol involves inhibition of lipopolysaccharide-induced inducible nitric oxidase synthase by heme oxygenase-1.
Immunopharmacology and immunotoxicology
Asami E,Kitami M,Ida T,Kobayashi T,Saeki M
Sun Oct 01 00:00:00 EDT 2023
CHST2-mediated sulfation of MECA79 antigens is critical for breast cancer cell migration and metastasis.
Cell death & disease
Zhang D,Zhang Y,Zou X,Li M,Zhang H,Du Y,Wang J,Peng C,Dong C,Hou Z
Mon Apr 24 00:00:00 EDT 2023
Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.
International immunopharmacology
Wu Q,Chen X,Qiao C,Cao X,Du Q,Yuan Y,Zuo Y,Miao Y,Zheng Z,Zhang T,Zang L,Yang X,Shi W,Xie Z,Xu Y,Wu D,Wen C,Zheng H
Sun Jan 01 00:00:00 EST 2023
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling.
Anesthesia and analgesia
Chen ZR,Hong Y,Wen SH,Zhan YQ,Huang WQ
Tue Aug 01 00:00:00 EDT 2023
GIPC2 is a tumor suppressor gene for acute myeloid leukemia and induces apoptosis of leukemia cells by regulating the PI3K/AKT pathway.
Epigenomics
Zhao J,Liu J,Liu S,Tian S,Yuan H,Li S
Wed Mar 01 00:00:00 EST 2023
Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry.
Journal of virology
Smith TJ,Fusco RM,Elmore ZC,Asokan A
Wed May 31 00:00:00 EDT 2023
Rab26 restricts insulin secretion via sequestering Synaptotagmin-1.
PLoS biology
Zhuang R,Zhou Y,Wang Z,Cao Y,Chen J,Xu L,Ren Y,Zheng Y,Wei Z,Qiu H,Li L,Han Y,Yun Y,Chen X,Hong W,Wang T
Thu Jun 01 00:00:00 EDT 2023
Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease.
Neuron
Hu J,Chen Q,Zhu H,Hou L,Liu W,Yang Q,Shen H,Chai G,Zhang B,Chen S,Cai Z,Wu C,Hong F,Li H,Chen S,Xiao N,Wang ZX,Zhang X,Wang B,Zhang L,Mo W
Wed Jan 04 00:00:00 EST 2023
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens.
Environmental science and pollution research international
Zhu H,Kulyar MF,Ding Y,Yao W,Mo Q,Li J
Wed Mar 01 00:00:00 EST 2023
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway.
Acta pharmacologica Sinica
Yang DG,Gao YY,Yin ZQ,Wang XR,Meng XS,Zou TF,Duan YJ,Chen YL,Liao CZ,Xie ZL,Fan XD,Sun L,Han JH,Yang XX
Wed Feb 01 00:00:00 EST 2023
SLC27A4-mediated selective uptake of mono-unsaturated fatty acids promotes ferroptosis defense in hepatocellular carcinoma.
Free radical biology & medicine
Li Z,Liao X,Hu Y,Li M,Tang M,Zhang S,Mo S,Li X,Chen S,Qian W,Feng R,Yu R,Xu Y,Yuan S,Xie C,Li J
Sat May 20 00:00:00 EDT 2023
Evidence for a lack of inotropic and chronotropic effects of glucagon and glucagon receptors in the human heart.
Cardiovascular diabetology
Aranda-Domene R,Orenes-Piñero E,Arribas-Leal JM,Canovas-Lopez S,Hernández-Cascales J
Tue May 30 00:00:00 EDT 2023
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Nature biotechnology
Klimas A,Gallagher BR,Wijesekara P,Fekir S,DiBernardo EF,Cheng Z,Stolz DB,Cambi F,Watkins SC,Brody SL,Horani A,Barth AL,Moore CI,Ren X,Zhao Y
Thu Jun 01 00:00:00 EDT 2023
Porphyromonas gingivalis Outer Membrane Vesicles Promote Apoptosis via msRNA-Regulated DNA Methylation in Periodontitis.
Microbiology spectrum
Fan R,Zhou Y,Chen X,Zhong X,He F,Peng W,Li L,Wang X,Xu Y
Tue Feb 14 00:00:00 EST 2023
Platelet-Derived Mitochondria Attenuate 5-FU-Induced Injury to Bone-Associated Mesenchymal Stem Cells.
Stem cells international
Chen Y,Liu Z,An N,Zhang J,Meng W,Wang W,Wu X,Hu X,Chen Y,Yin W
Fri Feb 10 00:00:00 EST 2023
IL-17C neutralization protects the kidney against acute injury and chronic injury.
EBioMedicine
Zhang F,Yin J,Liu L,Liu S,Zhang G,Kong Y,Wang Y,Wang N,Chen X,Wang F
Thu Jun 01 00:00:00 EDT 2023
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity.
The Journal of clinical investigation
Lin Q,Liu T,Wang X,Hou G,Xiang Z,Zhang W,Zheng S,Zhao D,Leng Q,Zhang X,Lu M,Guan T,Liu H,Hu Y
Thu Jun 01 00:00:00 EDT 2023
Design, Synthesis and Biological Evaluation of Histone Deacetylase Inhibitors Based on Pyrrolo[2,3-d]pyrimidine and Pyrrolo[2,3-b]pyridine Scaffolds.
ChemMedChem
Mao ND,Gao Y,Dang XW,Duan JL,Hui Z,Che H,Xu Y,Zhang H,He X,Garrido C,Ye XY
Mon Jul 17 00:00:00 EDT 2023
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases.
International journal of molecular sciences
Delaunay JL,Elbahnsi A,Bruneau A,Madry C,Durand-Schneider AM,Stary A,Housset C,Gautheron J,Callebaut I,Aït-Slimane T
Sun Jan 08 00:00:00 EST 2023
Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling.
Nutrients
Xie Y,Shen F,He Y,Guo C,Yang R,Cao H,Pan Q,Fan J
Thu Mar 02 00:00:00 EST 2023
Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liao Y,Li S,An J,Yu X,Tan X,Gui Y,Wang Y,Huang L,Zhou S,Wang D
Tue Jul 25 00:00:00 EDT 2023
TRAF6 Promotes PRMT5 Activity in a Ubiquitination-Dependent Manner.
Cancers
Liu L,Yin S,Gan W
Thu Apr 27 00:00:00 EDT 2023
The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection.
mBio
Hardy A,Bakshi S,Furnon W,MacLean O,Gu Q,Varjak M,Varela M,Aziz MA,Shaw AE,Pinto RM,Cameron Ruiz N,Mullan C,Taggart AE,Da Silva Filipe A,Randall RE,Wilson SJ,Stewart ME,Palmarini M
Tue Jun 27 00:00:00 EDT 2023
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Life (Basel, Switzerland)
Cafournet C,Zanin S,Guimier A,Hully M,Assouline Z,Barcia G,de Lonlay P,Steffann J,Munnich A,Bonnefont JP,Rötig A,Ruzzenente B,Metodiev MD
Sat Feb 04 00:00:00 EST 2023
Linear ubiquitination improves NFAT1 protein stability and facilitates NFAT1 signalling in Kawasaki disease.
The FEBS journal
Miao Y,Qian G,Zhang R,Yuan Y,Zuo Y,Ding Y,Li X,Tang Y,Zheng H,Lv H
Fri Sep 01 00:00:00 EDT 2023
Prophylaxis of posterior capsule opacification through autophagy activation with indomethacin-eluting intraocular lens.
Bioactive materials
Zhang X,Wang J,Xu J,Xu W,Zhang Y,Luo C,Ni S,Han H,Shentu X,Ye J,Ji J,Yao K
Mon May 01 00:00:00 EDT 2023
Dppa3 Improves the Germline Competence of Pluripotent Stem Cells.
Stem cell reviews and reports
Liu S,Zhao S,Zhang C,Tian C,Wang D,Yu H,Li Z,Liu L,Liu N
Tue Aug 01 00:00:00 EDT 2023
AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae in Apis mellifera.
International journal of molecular sciences
Chen WF,Wang HF,Wang Y,Liu ZG,Xu BH
Fri Jan 20 00:00:00 EST 2023
SNAP23 decreases insulin secretion by competitively inhibiting the interaction between SNAP25 and STX1A.
Bioscience reports
Chen J,Wang Z,Wang T,Cheng J,Zhuang R,Wang W
Wed May 31 00:00:00 EDT 2023
PGRMC1 Ablation Protects from Energy-Starved Heart Failure by Promoting Fatty Acid/Pyruvate Oxidation.
Cells
Lee SR,Mukae M,Jeong KJ,Park SH,Shin HJ,Kim SW,Won YS,Kwun HJ,Baek IJ,Hong EJ
Mon Feb 27 00:00:00 EST 2023
Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway.
Drug development research
Yu D,Li J,Wang Y,Guo D,Zhang X,Chen M,Zhou Z
Sat Apr 01 00:00:00 EDT 2023
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Cell death & disease
Zou X,Ma L,Zhang Y,Zhang Q,Xu C,Zhang D,Chu Y,Zhang J,Li M,Zhang H,Wang J,Peng C,Wei G,Wu Y,Hou Z,Jia H
Wed Jun 28 00:00:00 EDT 2023
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma.
Cancer biology & therapy
Han Y,Wang H,Chen H,Tan T,Wang Y,Yang H,Ding Y,Wang S
Sun Dec 31 00:00:00 EST 2023
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Journal of hypertension
Zhong X,Li Z,Xu Q,Peng H,Su Y,Le K,Shu Z,Liao Y,Ma Z,Pan X,Xu S,Zhou S
Mon May 01 00:00:00 EDT 2023
Functional Characterization of MC4R Variants in Chinese Morbid Obese Patients and Weight Loss after Bariatric Surgery.
Advanced biology
Gong Y,Wu Q,Huang S,Fu Z,Ye J,Liu R,Lin S,Guan W,Yang N,Li JZ,Liang H,Zhou H
Fri Sep 01 00:00:00 EDT 2023
UbcH5c-dependent activation of DNA-dependent protein kinase in response to replication-mediated DNA double-strand breaks.
Biochemical and biophysical research communications
Sakasai R,Matsui T,Sunatani Y,Iwabuchi K
Sun Aug 06 00:00:00 EDT 2023
TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes.
Physiological reports
Koma R,Shibaguchi T,Araiso Y,Yamada T,Nonaka Y,Jue T,Masuda K
Sat Apr 01 00:00:00 EDT 2023
Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats.
Scientific reports
Otsuka S,Itashiki Y,Tani A,Matsuoka T,Takada S,Matsuzaki R,Nakanishi K,Norimatsu K,Tachibe Y,Kitazato R,Nojima N,Kakimoto S,Kikuchi K,Maruyama I,Sakakima H
Tue Feb 07 00:00:00 EST 2023
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
Cell death and differentiation
Qin J,Huang T,Wang Z,Zhang X,Wang J,Dang Q,Cui D,Wang X,Zhai Y,Zhao L,Lu G,Shao C,Li S,Liu H,Liu Z
Sun Jan 01 00:00:00 EST 2023
FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth.
Signal transduction and targeted therapy
Wei W,Qin B,Wen W,Zhang B,Luo H,Wang Y,Xu H,Xie X,Liu S,Jiang X,Wang M,Tang Q,Zhang J,Yang R,Fan Z,Lyu H,Lin J,Li K,Lee MH
Fri May 19 00:00:00 EDT 2023
Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment.
Proceedings of the National Academy of Sciences of the United States of America
Mun DJ,Goo BS,Suh BK,Hong JH,Woo Y,Kim SJ,Kim S,Lee SB,Won Y,Yoo JY,Cho E,Jang EJ,Nhung TTM,Triet HM,An H,Lee H,Nguyen MD,Park SY,Baek ST,Park SK
Tue Feb 21 00:00:00 EST 2023
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.
Cell reports
Wen L,Yang X,Wu Z,Fu S,Zhan Y,Chen Z,Bi D,Shen Y
Tue Apr 25 00:00:00 EDT 2023
Adipocytes promote pancreatic cancer migration and invasion through fatty acid metabolic reprogramming.
Oncology reports
Cai Z,Li Y,Ma M,Wang L,Wang H,Liu M,Jiang C
Sat Jul 01 00:00:00 EDT 2023
Muscleblind-like 2 knockout shifts adducin 1 isoform expression and alters dendritic spine dynamics of cortical neurons during brain development.
Neuropathology and applied neurobiology
Huang CW,Lee KY,Lin PT,Nian FS,Cheng HY,Chang CH,Liao CY,Su YL,Seah C,Li C,Chen YF,Lee MH,Tsai JW
Sat Apr 01 00:00:00 EDT 2023
Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling.
Pediatric research
Huang C,Wang W,Huang H,Jiang J,Ding Y,Li X,Ma J,Hou M,Pu X,Qian G,Lv H
Thu Jun 01 00:00:00 EDT 2023
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
The Journal of cell biology
Gok MO,Connor OM,Wang X,Menezes CJ,Llamas CB,Mishra P,Friedman JR
Mon Apr 03 00:00:00 EDT 2023
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
Journal for immunotherapy of cancer
Wang X,Zhang Q,Zhou J,Xiao Z,Liu J,Deng S,Hong X,Huang W,Cai M,Guo Y,Huang J,Wang Y,Lin L,Zhu K
Wed Feb 01 00:00:00 EST 2023
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei.
Nature communications
Zhu J,Chen K,Sun YH,Ye W,Liu J,Zhang D,Su N,Wu L,Kou X,Zhao Y,Wang H,Gao S,Kang L
Tue Feb 21 00:00:00 EST 2023
The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury.
Neural regeneration research
Yu Z,Cheng X,Pan W,Yu C,Duan Y
Wed Nov 01 00:00:00 EDT 2023
Structural basis for FGF hormone signalling.
Nature
Chen L,Fu L,Sun J,Huang Z,Fang M,Zinkle A,Liu X,Lu J,Pan Z,Wang Y,Liang G,Li X,Chen G,Mohammadi M
Thu Jun 01 00:00:00 EDT 2023
STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhu L,Wang Z,Sun X,Yu J,Li T,Zhao H,Ji Y,Peng B,Du M
Wed Feb 01 00:00:00 EST 2023
Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis.
Antioxidants (Basel, Switzerland)
Zhang X,Cui K,Wang X,Tong Y,Liu C,Zhu Y,You Q,Jiang Z,Guo X
Mon May 08 00:00:00 EDT 2023
C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis.
Oncogene
Huang S,Li J,Wu S,Zheng Z,Wang C,Li H,Zhao L,Zhang X,Huang H,Huang C,Xie Q
Sat Apr 01 00:00:00 EDT 2023
Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis.
Asian journal of andrology
Wang XL,Li JM,Yuan SQ
Fri Apr 28 00:00:00 EDT 2023
Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics.
EMBO reports
Yun H,Jung M,Lee H,Jung S,Kim T,Kim N,Park SY,Kim WJ,Mun JY,Yoo JY
Thu Aug 03 00:00:00 EDT 2023
Specific Regulation of m6A by SRSF7 Promotes the Progression of Glioblastoma.
Genomics, proteomics & bioinformatics
Cun Y,An S,Zheng H,Lan J,Chen W,Luo W,Yao C,Li X,Huang X,Sun X,Wu Z,Hu Y,Li Z,Zhang S,Wu G,Yang M,Tang M,Yu R,Liao X,Gao G,Zhao W,Wang J,Li J
Tue Aug 01 00:00:00 EDT 2023
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Oncogene
Fang J,Zhang Y,Huang C,Lu R,Yu J,Chen R,Wang Y,Zhao X,Yu J,Huang J
Wed Mar 01 00:00:00 EST 2023
ZLN005 improves the survival of polymicrobial sepsis by increasing the bacterial killing via inducing lysosomal acidification and biogenesis in phagocytes.
Frontiers in immunology
Suzuki Y,Kami D,Taya T,Sano A,Ogata T,Matoba S,Gojo S
Mon Feb 27 00:00:00 EST 2023
GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer.
Frontiers in immunology
Yuan R,Zhang Y,Wang Y,Chen H,Zhang R,Hu Z,Chai C,Chen T
Wed May 24 00:00:00 EDT 2023
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
International journal of molecular sciences
Li L,Lv L,Xu JC,He Q,Chang N,Cui YY,Tao ZC,Zhu T,Qian LT
Wed Mar 15 00:00:00 EDT 2023
Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy.
Cancer biology & medicine
Chen H,Yin L,Yang J,Ren N,Chen J,Lu Q,Huang Y,Feng Y,Wang W,Wang S,Liu Y,Song Y,Li Y,Jin J,Tan W,Lin D
Thu May 04 00:00:00 EDT 2023
Stimulation of functional recovery via neurorepair mechanisms by the traditional Japanese Kampo medicine, Ninjin'yoeito, and physical exercise in a rat ischemic stroke model.
Journal of ethnopharmacology
Tani A,Sakakima H,Otsuka S,Mizuno K,Nakanishi K,Norimatsu K,Takada S,Matsuoka T,Matsuzaki R,Nakakogawa T,Maruyama I
Fri Feb 10 00:00:00 EST 2023
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
Journal of medicinal chemistry
Yuan K,Shen H,Zheng M,Xia F,Li Q,Chen W,Ji M,Yang H,Zhuang X,Cai Z,Min W,Wang X,Xiao Y,Yang P
Thu Mar 23 00:00:00 EDT 2023
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Laboratory investigation; a journal of technical methods and pathology
Cai MN,Chen DM,Xiao LX,Li SS,Liao CH,Li J,Huang ZX,Wang JL,Gu YR,Gu L,Huang YH,Lian YF
Sat Jul 01 00:00:00 EDT 2023
PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression.
Cell & bioscience
Chen L,Dong W,Zhou M,Yang C,Xiong M,Kazobinka G,Chen Z,Xing Y,Hou T
Mon Mar 06 00:00:00 EST 2023
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
Current issues in molecular biology
Yang Y,Cai Y,Guo J,Dai K,Liu L,Chen Z,Wang F,Deng M
Fri Apr 07 00:00:00 EDT 2023
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cell death & disease
Cheng L,He Q,Liu B,Chen L,Lv F,Li X,Li Y,Liu C,Song Y,Xing Y
Tue Jan 31 00:00:00 EST 2023
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Biomedicines
Qiu Q,Guo G,Guo X,Hu X,Yu T,Liu G,Zhang H,Chen Y,She J
Mon Mar 13 00:00:00 EDT 2023
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Neuron
Festa BP,Siddiqi FH,Jimenez-Sanchez M,Won H,Rob M,Djajadikerta A,Stamatakou E,Rubinsztein DC
Wed Jul 05 00:00:00 EDT 2023
BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion.
International immunopharmacology
Guo K,Shang Y,Wang Z,Li Y,Chen J,Zhu B,Zhang D,Chen J
Thu Jun 01 00:00:00 EDT 2023
Fecal microbiota transplantation ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota in db/db mice.
BMJ open diabetes research & care
Chen L,Guo L,Feng S,Wang C,Cui Z,Wang S,Lu Q,Chang H,Hang B,Snijders AM,Mao JH,Lu Y,Ding D
Mon May 01 00:00:00 EDT 2023
Aluminum induces neuroinflammation via P2X7 receptor activating NLRP3 inflammasome pathway.
Ecotoxicology and environmental safety
Zhu X,Hao W,Liu Z,Song Y,Hao C,Wu S,Lu X,Yang J,Jin C
Sun Jan 01 00:00:00 EST 2023
Prognostic role and immune infiltration characteristics of EI24 in multiple cancer types.
Expert review of molecular diagnostics
Yang W,Zhou W,Zhao X,Duan L,Niu L,Zhang Y,Li Y,Wang X,Chen J,Fan A,Xie Q,Liu J,Han Y,Fan D,Hong L
Mon May 01 00:00:00 EDT 2023
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.
Biochimica et biophysica acta. Gene regulatory mechanisms
Hu X,Zou R,Zhang Z,Ji J,Li J,Huo XY,Liu D,Ge MX,Cui MK,Wu MZ,Li ZP,Wang Q,Zhang X,Zhang ZR
Thu Jun 01 00:00:00 EDT 2023
RNA localization to the mitotic spindle is essential for early development and is regulated by kinesin-1 and dynein.
Journal of cell science
Remsburg CM,Konrad KD,Song JL
Wed Mar 01 00:00:00 EST 2023
Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis.
Theranostics
Li Y,Chai JL,Shi X,Feng Y,Li JJ,Zhou LN,Cao C,Li KR
Wed May 10 00:00:00 EDT 2023
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Blood
Cheng Q,Wang D,Lai X,Liu Y,Zuo Y,Zhang W,Lei L,Chen J,Liu H,Wang Y,Liu H,Zheng H,Wu D,Xu Y
Thu Mar 23 00:00:00 EDT 2023
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Biomedicines
Yang Y,Ding T,Xiao G,Huang J,Luo D,Yue M,Su Y,Jiang S,Zeng J,Liu Y
Sun Feb 05 00:00:00 EST 2023
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
Molecular cancer research : MCR
Liao X,Li Z,Zheng H,Qian W,Zhang S,Chen S,Li X,Tang M,Xu Y,Yu R,Li M,Song L,Li J
Wed Jul 05 00:00:00 EDT 2023
Cytoskeletal protein SPTA1 mediating the decrease in erectile function induced by high-fat diet via Hippo signaling pathway.
Andrology
Chen Y,Wang L,Huang ZS,Feng JX,Li SX,Du ZJ,Zhang ZB,Liu J,Yang J,Hu ZM,Wang ZL,Chen J
Wed Mar 01 00:00:00 EST 2023
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Cell reports
Jiang X,Liu K,Jiang H,Yin H,Wang ED,Cheng H,Yuan F,Xiao F,Wang F,Lu W,Peng B,Shu Y,Li X,Chen S,Guo F
Tue Jan 31 00:00:00 EST 2023
Vitamin C promotes ACE2 degradation and protects against SARS-CoV-2 infection.
EMBO reports
Zuo Y,Zheng Z,Huang Y,He J,Zang L,Ren T,Cao X,Miao Y,Yuan Y,Liu Y,Ma F,Dai J,Tian S,Ding Q,Zheng H
Wed Apr 05 00:00:00 EDT 2023
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.
Cancers
Caballero-Ruiz B,Gkotsi DS,Ollerton H,Morales-Alcala CC,Bordone R,Jenkins GML,Di Magno L,Canettieri G,Riobo-Del Galdo NA
Fri Jan 06 00:00:00 EST 2023
RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.
Molecular cell
Li Y,Huang J,Bao L,Zhu J,Duan W,Zheng H,Wang H,Jiang Y,Liu W,Zhang M,Yu Y,Yi C,Ji X
Thu Apr 20 00:00:00 EDT 2023
Repositioning linifanib as a potent anti-necroptosis agent for sepsis.
Cell death discovery
Yu L,Yang K,He X,Li M,Gao L,Zha Y
Fri Feb 10 00:00:00 EST 2023
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
The Journal of clinical investigation
Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L
Fri Apr 01 00:00:00 EDT 2022
RAD51 is essential for spermatogenesis and male fertility in mice.
Cell death discovery
Qin J,Huang T,Wang J,Xu L,Dang Q,Xu X,Liu H,Liu Z,Shao C,Zhang X
Tue Mar 15 00:00:00 EDT 2022
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication.
Chemico-biological interactions
Wang Q,Chen W,Zhang B,Gao Z,Zhang Q,Deng H,Han L,Shen XL
Fri Feb 25 00:00:00 EST 2022
MiR-15p-5p Mediates the Coordination of ICAM-1 and FAK to Promote Endothelial Cell Proliferation and Migration.
Inflammation
Gu W,Zhang L,Zhang X,Wang B,Shi X,Hu K,Ye Y,Liu G
Wed Jun 01 00:00:00 EDT 2022
Critical Role of Cathepsin L/V in Regulating Endothelial Cell Senescence.
Biology
Li C,Liu Z,Chen M,Zhang L,Shi R,Zhong H
Mon Dec 26 00:00:00 EST 2022
DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway.
Science signaling
Liu L,Dai X,Yin S,Liu P,Hill EG,Wei W,Gan W
Tue Jan 04 00:00:00 EST 2022
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Science advances
Zuo Y,He J,Liu S,Xu Y,Liu J,Qiao C,Zang L,Sun W,Yuan Y,Zhang H,Chen X,Jin L,Miao Y,Huang F,Ren T,Wang J,Qian F,Zhu C,Zhang W,Liu Y,Xu G,Ma F,Zheng H
Fri Apr 08 00:00:00 EDT 2022
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Cellular and molecular life sciences : CMLS
Zhou T,Chen T,Lai B,Zhang W,Luo X,Xia D,Fu W,Xu J
Mon May 02 00:00:00 EDT 2022
ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation.
Scientific reports
Azzarelli R,McNally A,Dell'Amico C,Onorati M,Simons B,Philpott A
Fri Feb 11 00:00:00 EST 2022
cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence.
Protein & cell
Li X,Li X,Xie C,Cai S,Li M,Jin H,Wu S,Cui J,Liu H,Zhao Y
Sat Jan 01 00:00:00 EST 2022
A long non-coding RNA as a direct vitamin D target transcribed from the antisense strand of the human HSD17B2 locus.
Bioscience reports
Kanemoto Y,Nishimura K,Hayakawa A,Sawada T,Amano R,Mori J,Kurokawa T,Murakami Y,Kato S
Fri May 27 00:00:00 EDT 2022
Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway.
International immunopharmacology
Yao TT,Zhang Y,He RL,Lv X,He YJ,Li MY,Han YY,Long LZ,Jiang GL,Cheng XY,Hu GY,Li QB,Tao LJ,Meng J
Thu Dec 01 00:00:00 EST 2022
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
International immunopharmacology
Wang X,Duan C,Li Y,Lu H,Guo K,Ge X,Chen T,Shang Y,Liu H,Zhang D
Sat Oct 01 00:00:00 EDT 2022
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
International immunopharmacology
Wang X,Duan C,Li Y,Lu H,Guo K,Ge X,Chen T,Shang Y,Liu H,Zhang D
Sat Oct 01 00:00:00 EDT 2022
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Nature metabolism
Zhang CS,Li M,Wang Y,Li X,Zong Y,Long S,Zhang M,Feng JW,Wei X,Liu YH,Zhang B,Wu J,Zhang C,Lian W,Ma T,Tian X,Qu Q,Yu Y,Xiong J,Liu DT,Wu Z,Zhu M,Xie C,Wu Y,Xu Z,Yang C,Chen J,Huang G,He Q,Huang X,Zhang L,Sun X,Liu Q,Ghafoor A,Gui F,Zheng K,Wang W,Wang ZC,Yu Y,Zhao Q,Lin SY,Wang ZX,Piao HL,Deng X,Lin SC
Sat Oct 01 00:00:00 EDT 2022
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Cancer letters
Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y
Tue Nov 01 00:00:00 EDT 2022
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Cancer letters
Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y
Tue Nov 01 00:00:00 EDT 2022
Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation.
Nature communications
Xie Z,Hou L,Shen S,Wu Y,Wang J,Jie Z,Zhao X,Li X,Zhang X,Chen J,Xu W,Ning L,Ma Q,Wang S,Wang H,Yuan P,Fang X,Qin A,Fan S
Mon Jan 10 00:00:00 EST 2022
A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.
Bioorganic chemistry
Yao S,Yin J,Liu W,Li Y,Huang J,Qi C,Hu Z,Tong Q,Gu L,Zhang Y
Sat Oct 01 00:00:00 EDT 2022
Isolation of five different primary cell types from a single sample of human skin.
STAR protocols
Kabacik S,Lowe D,Cohen H,Felton S,Spitzer J,Raj K
Fri Jun 17 00:00:00 EDT 2022
Neddylation is essential for β-catenin degradation in Wnt signaling pathway.
Cell reports
Wang B,Wang T,Zhu H,Yan R,Li X,Zhang C,Tao W,Ke X,Hao P,Qu Y
Tue Mar 22 00:00:00 EDT 2022
Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice.
Evidence-based complementary and alternative medicine : eCAM
Wu M,Kang Q,Kang Y,Tong Y,Yang T,Fan Y
Sat Dec 10 00:00:00 EST 2022
The identification of alternative oxidase in intermediate host snails of Schistosoma and its potential role in protecting Oncomelania hupensis against niclosamide-induced stress.
Parasites & vectors
Jiang N,Li SZ,Zhang YW,Habib MR,Xiong T,Xu S,Dong H,Zhao QP
Mon Mar 21 00:00:00 EDT 2022
Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.
International journal of molecular sciences
Han M,Li Y,Guo Y,Zhu W,Jiang J
Sun Nov 13 00:00:00 EST 2022
Inhibiting STAT5 significantly attenuated Ang II-induced cardiac dysfunction and inflammation.
European journal of pharmacology
Jin G,Wang L,Ma J
Sat Jan 15 00:00:00 EST 2022
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Theranostics
Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T
Thu Mar 10 00:00:00 EST 2022
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Frontiers in cellular neuroscience
Wang Y,Luo K,Li J,Liao Y,Liao C,Chen WS,Chen M,Ao L
Sat Jul 16 00:00:00 EDT 2022
Protocol for isolation and proteostatic analysis of sub-populations of spermatogenic cells in mouse.
STAR protocols
Zou Q,Yang L,Qi H
Fri Jun 17 00:00:00 EDT 2022
lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization.
Research (Washington, D.C.)
Zhao K,Wang X,Zhao D,Lin Q,Zhang Y,Hu Y
Tue Aug 02 00:00:00 EDT 2022
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.
Cell death discovery
Zhou Y,Yong H,Cui W,Chu S,Li M,Li Z,Bai J,Zhang H
Mon Apr 11 00:00:00 EDT 2022
D609 inhibition of phosphatidylcholine-specific phospholipase C attenuates prolonged insulin stimulation-mediated GLUT4 downregulation in 3T3-L1 adipocytes.
Journal of physiology and biochemistry
Ma J,Zhang X,Song Y,Qin Y,Tan Y,Zheng L,Cheng B,Xi X
Sun May 01 00:00:00 EDT 2022
S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.
Frontiers in oncology
Huang W,Zou L,Hao Z,Wang B,Mao F,Duan Q,Guo D
Sat Jul 16 00:00:00 EDT 2022
STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment.
Cancer cell international
Pu Z,Liu J,Liu Z,Peng F,Zhu Y,Wang X,He J,Yi P,Hu X,Fan X,Chen J
Wed Oct 12 00:00:00 EDT 2022
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
Cell death & disease
Zheng ZY,Chu MY,Lin W,Zheng YQ,Xu XE,Chen Y,Liao LD,Wu ZY,Wang SH,Li EM,Xu LY
Wed May 25 00:00:00 EDT 2022
ER proteins decipher the tubulin code to regulate organelle distribution.
Nature
Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C
Sat Jan 01 00:00:00 EST 2022
ER proteins decipher the tubulin code to regulate organelle distribution.
Nature
Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C
Sat Jan 01 00:00:00 EST 2022
ER proteins decipher the tubulin code to regulate organelle distribution.
Nature
Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C
Sat Jan 01 00:00:00 EST 2022
ER proteins decipher the tubulin code to regulate organelle distribution.
Nature
Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C
Sat Jan 01 00:00:00 EST 2022
Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.
Viral immunology
Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z
Sat Oct 01 00:00:00 EDT 2022
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
International immunopharmacology
He J,Liu L,Liu X,Chen H,Liu K,Huang N,Wang Y
Thu Dec 01 00:00:00 EST 2022
Analysis of the Effects of Ninjin'yoeito on Physical Frailty in Mice.
International journal of molecular sciences
Otsuka S,Fukumaru K,Tani A,Takada S,Kikuchi K,Norimatsu K,Matsuzaki R,Matsuoka T,Sakakima H,Omiya Y,Mizuno K,Matsubara Y,Maruyama I
Fri Sep 23 00:00:00 EDT 2022
Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1.
Autophagy
Shao T,Ke H,Liu R,Xu L,Han S,Zhang X,Dang Y,Jiao X,Li W,Chen ZJ,Qin Y,Zhao S
Mon Aug 01 00:00:00 EDT 2022
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Nature communications
Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW
Mon Nov 28 00:00:00 EST 2022
Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair.
Science advances
Liu L,Lin B,Yin S,Ball LE,Delaney JR,Long DT,Gan W
Fri Dec 09 00:00:00 EST 2022
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
Neuropharmacology
Yang C,Kang F,Huang X,Zhang W,Wang S,Han M,Zhang Z,Li J
Thu Dec 01 00:00:00 EST 2022
Secondary structure RNA elements control the cleavage activity of DICER.
Nature communications
Nguyen TD,Trinh TA,Bao S,Nguyen TA
Tue Apr 19 00:00:00 EDT 2022
Papain-like protease of SARS-CoV-2 inhibits RLR signaling in a deubiquitination-dependent and deubiquitination-independent manner.
Frontiers in immunology
Ran XH,Zhu JW,Chen YY,Ni RZ,Mu D
Tue Aug 30 00:00:00 EDT 2022
Asparaginyl endopeptidase protects against podocyte injury in diabetic nephropathy through cleaving cofilin-1.
Cell death & disease
Lei C,Li M,Qiu Y,Xie Y,Hao Z,Yin X,Zhang Z,Su H,Yang L,Lin J,Hammes HP,Zhang C
Fri Feb 25 00:00:00 EST 2022
SIX1 Predicts Poor Prognosis and Facilitates the Progression of Non-small Lung Cancer via Activating the Notch Signaling Pathway.
Journal of Cancer
Huang S,Lin W,Wang L,Gao Y,Yuan X,Zhang P,Chen Y,Chu Q
Tue Jan 25 00:00:00 EST 2022
In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.
International journal of molecular sciences
Mareux E,Lapalus M,Ben Saad A,Zelli R,Lakli M,Riahi Y,Almes M,Banet M,Callebaut I,Decout JL,Falguières T,Jacquemin E,Gonzales E
Thu Sep 15 00:00:00 EDT 2022
In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.
International journal of molecular sciences
Mareux E,Lapalus M,Ben Saad A,Zelli R,Lakli M,Riahi Y,Almes M,Banet M,Callebaut I,Decout JL,Falguières T,Jacquemin E,Gonzales E
Thu Sep 15 00:00:00 EDT 2022
Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model.
Redox biology
Pei Z,Qin Y,Fu X,Yang F,Huo F,Liang X,Wang S,Cui H,Lin P,Zhou G,Yan J,Wu J,Chen ZN,Zhu P
Tue Nov 01 00:00:00 EDT 2022
LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.
Bioengineered
Sun Z,Xue C,Li J,Zhao H,Du Y,Du N
Tue Mar 01 00:00:00 EST 2022
Rare POLN mutations confer risk for familial nasopharyngeal carcinoma through weakened Epstein-Barr virus lytic replication.
EBioMedicine
Xiao RW,Wang F,Wang TM,Zhang JB,Wu ZY,Deng CM,Liao Y,Zhou T,Yang DW,Dong SQ,Xue WQ,He YQ,Zheng XH,Li XZ,Zhang PF,Zhang SD,Hu YZ,Liu YY,Xia YF,Gao S,Mu JB,Feng L,Jia WH
Sat Oct 01 00:00:00 EDT 2022
SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner.
Emerging microbes & infections
Zhou YQ,Wang K,Wang XY,Cui HY,Zhao Y,Zhu P,Chen ZN
Thu Dec 01 00:00:00 EST 2022
Naringenin Promotes Myotube Formation and Maturation for Cultured Meat Production.
Foods (Basel, Switzerland)
Yan Q,Fei Z,Li M,Zhou J,Du G,Guan X
Tue Nov 22 00:00:00 EST 2022
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination.
Genes & diseases
Yuan G,Yang S,Yang S
Thu Sep 01 00:00:00 EDT 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease.
Acta pharmacologica Sinica
Yin F,Zheng PQ,Zhao LQ,Wang YZ,Miao NJ,Zhou ZL,Cheng Q,Chen PP,Xie HY,Li JY,Ni JY,Zhou L,Zhang W,Wang XX,Liu J,Lu LM
Sat Jan 01 00:00:00 EST 2022
Profile analysis and functional modeling identify circular RNAs in nonalcoholic fatty liver disease as regulators of hepatic lipid metabolism.
Frontiers in genetics
Xie Y,Cao Y,Guo CJ,Guo XY,He YF,Xu QY,Shen F,Pan Q
Tue Oct 04 00:00:00 EDT 2022
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.
Cell death & disease
Xiao J,Zhang L,Yi H,Zou L,Mo J,Xue F,Zheng J,Huang Y,Lu H,Wu H,Xue P,Zhang X,He L,Li Z,Pang S,Qiao G,Duan Q,Zhu F
Tue Sep 27 00:00:00 EDT 2022
SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1.
Cellular & molecular immunology
Zhang S,Wang J,Wang L,Aliyari S,Cheng G
Mon Aug 01 00:00:00 EDT 2022
BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells.
BMC oral health
Liu C,Yu J,Liu B,Liu M,Song G,Zhu L,Peng B
Thu Nov 24 00:00:00 EST 2022
C3/C3aR inhibition alleviates GMH-IVH-induced hydrocephalus by preventing microglia-astrocyte interactions in neonatal rats.
Neuropharmacology
Tang J,Jila S,Luo T,Zhang B,Miao H,Feng H,Chen Z,Zhu G
Tue Mar 01 00:00:00 EST 2022
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Oncogene
Hao X,Bu W,Lv G,Xu L,Hou D,Wang J,Liu X,Yang T,Zhang X,Liu Q,Gong Y,Shao C
Sat Jan 01 00:00:00 EST 2022
A comparative study of Mesenchymal Stem Cells transplantation approach to antagonize age-associated ovarian hypofunction with consideration of safety and efficiency.
Journal of advanced research
Wang L,Mei Q,Xie Q,Li H,Su P,Zhang L,Li K,Ma D,Chen G,Li J,Xiang W
Sun May 01 00:00:00 EDT 2022
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
EMBO reports
Yuan Y,Miao Y,Ren T,Huang F,Qian L,Chen X,Zuo Y,Zhang HG,He J,Qiao C,Du Q,Wu Q,Zhang W,Zhu C,Xu Y,Wu D,Shi W,Jiang J,Xu G,Zheng H
Wed Jan 05 00:00:00 EST 2022
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
International journal of molecular sciences
Gu H,Zhu S,Peng C,Wei Z,Shen Y,Yuan C,Yang H,Cui H,Yang L
Mon Sep 05 00:00:00 EDT 2022
Recycling of autophagosomal components from autolysosomes by the recycler complex.
Nature cell biology
Zhou C,Wu Z,Du W,Que H,Wang Y,Ouyang Q,Jian F,Yuan W,Zhao Y,Tian R,Li Y,Chen Y,Gao S,Wong CCL,Rong Y
Fri Apr 01 00:00:00 EDT 2022
HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells.
Journal of experimental & clinical cancer research : CR
Wu AC,Yang WB,Chang KY,Lee JS,Liou JP,Su RY,Cheng SM,Hwang DY,Kikkawa U,Hsu TI,Wang CY,Chang WC,Chen PY,Chuang JY
Wed Feb 02 00:00:00 EST 2022
LPS-Induced Activation of the cGAS-STING Pathway is Regulated by Mitochondrial Dysfunction and Mitochondrial DNA Leakage in Endometritis.
Journal of inflammation research
Li MZ,Wen XY,Liu XQ,Wang YQ,Yan L
Sat Oct 15 00:00:00 EDT 2022
Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis.
Molecular cell
Xu W,He C,Kaye EG,Li J,Mu M,Nelson GM,Dong L,Wang J,Wu F,Shi YG,Adelman K,Lan F,Shi Y,Shen H
Thu Mar 17 00:00:00 EDT 2022
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Frontiers in pharmacology
Li J,Jiang Y,Dai Q,Yu Y,Lv X,Zhang Y,Liao X,Ao L,Hu G,Meng J,Peng Z,Tao L,Xie Y
Mon Apr 24 00:00:00 EDT 2023
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways.
Frontiers in pharmacology
Huang LJ,Wang YM,Gong LQ,Hu C,Gui Y,Zhang C,Tan X,Yu XK,Liao YL,Luo Y,Tang YQ,Dai YF,Deng Y,Wang D,Guo DL
Sat Jul 16 00:00:00 EDT 2022
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Cancer letters
Li TJ,Jin KZ,Li H,Ye LY,Li PC,Jiang B,Lin X,Liao ZY,Zhang HR,Shi SM,Lin MX,Fei QL,Xiao ZW,Xu HX,Liu L,Yu XJ,Wu WD
Fri Apr 01 00:00:00 EDT 2022
Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly.
Cell proliferation
Cao Y,Zhu X,Zhen P,Tian Y,Ji D,Xue K,Yan W,Chai J,Liu H,Wang W
Thu Dec 01 00:00:00 EST 2022
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
Journal of oral microbiology
Wang L,Pu W,Wang C,Lei L,Li H
Fri Apr 29 00:00:00 EDT 2022
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
Journal of oral microbiology
Wang L,Pu W,Wang C,Lei L,Li H
Fri Apr 29 00:00:00 EDT 2022
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
Journal of oral microbiology
Wang L,Pu W,Wang C,Lei L,Li H
Fri Apr 29 00:00:00 EDT 2022
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
Journal of oral microbiology
Wang L,Pu W,Wang C,Lei L,Li H
Fri Apr 29 00:00:00 EDT 2022
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
The Science of the total environment
Zhou J,Zeng L,Zhang Y,Wang M,Li Y,Jia Y,Wu L,Su P
Tue Nov 15 00:00:00 EST 2022
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Frontiers in endocrinology
Wang C,Sun Y
Tue Apr 19 00:00:00 EDT 2022
BRCC36 prevents vascular calcification in chronic kidney disease through the β-catenin signalling pathway.
Experimental cell research
Xie C,Chen C,Wu L,Xiong Y,Xing C,Mao H
Fri Apr 01 00:00:00 EDT 2022
4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects.
FEBS open bio
Birus R,El-Awaad E,Ballentin L,Alchab F,Aichele D,Ettouati L,Götz C,Le Borgne M,Jose J
Tue Feb 01 00:00:00 EST 2022
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Molecular biology reports
Xu H,Cui Y,Liu X,Zheng X,Liu J,Hu X,Gao F,Hu X,Li M,Wei X,Gao Y,Zhao Y
Tue Mar 01 00:00:00 EST 2022
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Journal of medicinal chemistry
Zhang S,Chen X,Wu C,Xu H,Xie X,Feng M,Hu S,Bai H,Gao F,Tong L,Ding J,Liu H,Xie Z,Wang J
Thu Jun 09 00:00:00 EDT 2022
Alternative polyadenylation by sequential activation of distal and proximal PolyA sites.
Nature structural & molecular biology
Tang P,Yang Y,Li G,Huang L,Wen M,Ruan W,Guo X,Zhang C,Zuo X,Luo D,Xu Y,Fu XD,Zhou Y
Sat Jan 01 00:00:00 EST 2022
Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma.
Cells
Li X,Chen Q,Liu J,Lai S,Zhang M,Zhen T,Hu H,Gao X,Wong AST,Zeng JZ
Thu Dec 01 00:00:00 EST 2022
Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment.
Cell reports. Medicine
Mei Z,Yang T,Liu Y,Gao Y,Hou Z,Zhuang Q,He D,Zhang X,Tan Q,Zhu X,Qin Y,Chen X,Xu C,Bian C,Wang X,Wang C,Wu D,Huang S,Li Z
Tue May 17 00:00:00 EDT 2022
Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.
Nature communications
Wang L,Wen X,Wang Z,Lin Z,Li C,Zhou H,Yu H,Li Y,Cheng Y,Chen Y,Lou G,Pan J,Cao M
Sat Jul 09 00:00:00 EDT 2022
Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.
Nature communications
Wang L,Wen X,Wang Z,Lin Z,Li C,Zhou H,Yu H,Li Y,Cheng Y,Chen Y,Lou G,Pan J,Cao M
Sat Jul 09 00:00:00 EDT 2022
MEIG1 determines the manchette localization of IFT20 and IFT88, two intraflagellar transport components in male germ cells.
Developmental biology
Yap YT,Shi L,Zhang D,Huang Q,Siddika F,Wang Z,Li W,Zhang Z
Sun May 01 00:00:00 EDT 2022
Antagonistic action of a synthetic androgen ligand mediated by chromatin remodeling in a human prostate cancer cell line.
Biochemical and biophysical research communications
Sawada T,Kanemoto Y,Amano R,Hayakawa A,Kurokawa T,Mori J,Kato S
Tue Jul 05 00:00:00 EDT 2022
Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway.
Lipids in health and disease
Xiong H,Ye J,Xie K,Hu W,Xu N,Yang H
Thu Dec 29 00:00:00 EST 2022
Maternal Factor Dppa3 Activates 2C-Like Genes and Depresses DNA Methylation in Mouse Embryonic Stem Cells.
Frontiers in cell and developmental biology
Zhang C,Wen H,Liu S,Fu E,Yu L,Chen S,Han Q,Li Z,Liu N
Sat Jul 16 00:00:00 EDT 2022
The involvement of the primo vascular system in local enteritis and its modification by electroacupuncture.
Frontiers in immunology
Nan S,Wan J,Lei Q,Wang X,Ma N,Yin R,Zhu J,Ding M,Ding Y
Tue Jan 31 00:00:00 EST 2023
STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages.
Oxidative medicine and cellular longevity
Wu XY,Chen YJ,Liu CA,Gong JH,Xu XS
Thu Mar 24 00:00:00 EDT 2022
Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood-Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight Junction Protein Reduction in Rat Stroke Model.
Frontiers in cellular neuroscience
Huang LY,Song JX,Cai H,Wang PP,Yin QL,Zhang YD,Chen J,Li M,Song JJ,Wang YL,Luo L,Wang W,Qi SH
Tue Mar 22 00:00:00 EDT 2022
ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.
Journal of molecular biology
Chen G,Yang Y,Wu QJ,Cao L,Ruan W,Shao C,Jiang L,Tang P,Ma S,Jiang A,Wang Z,Wu K,Zhang QC,Fu XD,Zhou Y
Fri Apr 15 00:00:00 EDT 2022
HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.
British journal of cancer
Zhang G,Tan R,Wan S,Yang R,Hu X,Zhao E,Ding X,Zhang J,Li B,Liang P,Cui H
Tue Nov 01 00:00:00 EDT 2022
Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.
Cell reports
Liang C,Zhang S,Robinson D,Ploeg MV,Wilson R,Nah J,Taylor D,Beh S,Lim R,Sun L,Muoio DM,Stroud DA,Ho L
Tue Aug 16 00:00:00 EDT 2022
Trichodimerol inhibits inflammation through suppression of the nuclear transcription factor-kappaB/NOD-like receptor thermal protein domain associated protein 3 signaling pathway.
Frontiers in microbiology
Huo XY,Lei LR,Guo WX,Hu YJ,Kuang QX,Liu MD,Peng W,Dai YF,Wang D,Gu YC,Guo DL,Deng Y
Mon Sep 12 00:00:00 EDT 2022
Acetylation of fructose-bisphosphate aldolase-mediated glycolysis is essential for Bombyx mori nucleopolyhedrovirus infection.
Microbial pathogenesis
Gao X,Xu S,Mo Y,Zhu Y,Chen X,Miao M,Quan Y,Yu W
Thu Sep 01 00:00:00 EDT 2022
Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang YF,Chang YY,Zhang XM,Gao MT,Zhang QL,Li X,Zhang L,Yao WF
Sun May 01 00:00:00 EDT 2022
The deubiquitinase USP10 protects pancreatic cancer cells from endoplasmic reticulum stress.
NPJ precision oncology
Bhattacharya U,Thavathiru E,Neizer-Ashun F,Xu C,Gatalica Z,Dwivedi SKD,Dey A,Mukherjee P,Bhattacharya R
Wed Dec 21 00:00:00 EST 2022
An acetylated mannan isolated from Aloe vera induce colorectal cancer cells apoptosis via mitochondrial pathway.
Carbohydrate polymers
Tong X,Lao C,Li D,Du J,Chen J,Xu W,Li L,Ye H,Guo X,Li J
Thu Sep 01 00:00:00 EDT 2022
D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia.
iScience
Florio E,Serra M,Lewis RG,Kramár E,Freidberg M,Wood M,Morelli M,Borrelli E
Fri Oct 21 00:00:00 EDT 2022
GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis.
Oncogenesis
Zhao C,Yu H,Fan X,Niu W,Fan J,Sun S,Gong M,Zhao B,Fang Z,Chen X
Mon May 23 00:00:00 EDT 2022
Progerin-expressing endothelial cells are unable to adapt to shear stress.
Biophysical journal
Danielsson BE,Peters HC,Bathula K,Spear LM,Noll NA,Dahl KN,Conway DE
Tue Feb 15 00:00:00 EST 2022
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis.
Frontiers in pharmacology
Chen R,Zeng J,Li C,Xiao H,Li S,Lin Z,Huang K,Shen J,Huang H
Wed Apr 13 00:00:00 EDT 2022
Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway.
Cancer cell international
Li P,Li L,Li Z,Wang S,Li R,Zhao W,Feng Y,Huang S,Li L,Qiu H,Xia S
Thu Jan 06 00:00:00 EST 2022
Multiple ciliary localization signals control INPP5E ciliary targeting.
eLife
Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR
Mon Sep 05 00:00:00 EDT 2022
Multiple ciliary localization signals control INPP5E ciliary targeting.
eLife
Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR
Mon Sep 05 00:00:00 EDT 2022
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.
Frontiers in cellular neuroscience
Cheng L,Su Y,Zhi K,Xie Y,Zhang C,Meng X
Tue Oct 11 00:00:00 EDT 2022
Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy.
Nature communications
Zhao M,Wei H,Li C,Zhan R,Liu C,Gao J,Yi Y,Cui X,Shan W,Ji L,Pan B,Cheng S,Song M,Sun H,Jiang H,Cai J,Garcia-Barrio MT,Chen YE,Meng X,Dong E,Wang DW,Zheng L
Fri Apr 01 00:00:00 EDT 2022
Genome-Wide Analysis of the Indispensable Role of Non-structural Proteins in the Replication of SARS-CoV-2.
Frontiers in microbiology
Jin Y,Ouyang M,Yu T,Zhuang J,Wang W,Liu X,Duan F,Guo D,Peng X,Pan JA
Sat Jul 16 00:00:00 EDT 2022
Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma.
Cells
Zrimšek M,Kuchaříková H,Draganić K,Dobrovolná P,Heiss Spornberger V,Winkelmayer L,Hassler MR,Lochmanová G,Zdráhal Z,Egger G
Tue Aug 02 00:00:00 EDT 2022
Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression.
Journal of molecular cell biology
Li Y,Yang C,Wang H,Zhao L,Kong Q,Cang Y,Zhao S,Lv L,Li Y,Mao B,Ma P
Tue Apr 05 00:00:00 EDT 2022
Circ_0004087 interaction with SND1 promotes docetaxel resistance in prostate cancer by boosting the mitosis error correction mechanism.
Journal of experimental & clinical cancer research : CR
Chen L,Song Y,Hou T,Li X,Cheng L,Li Y,Xing Y
Fri Jun 03 00:00:00 EDT 2022
Hypotonic induction of aquaporin5 expression in rat astrocytes through p38 MAPK pathway.
Anatomia, histologia, embryologia
Yi Y,Qiu G,Liu H,Gao F,Liu X,Chen Y,Yang M
Tue Nov 01 00:00:00 EDT 2022
Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes.
Frontiers in pharmacology
Lin Z,Li Z,Guo Z,Cao Y,Li J,Liu P,Li Z
Sat Jul 16 00:00:00 EDT 2022
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Carcinogenesis
Zeng Q,Jin F,Qian H,Chen H,Wang Y,Zhang D,Wei Y,Chen T,Guo B,Chai C
Thu Mar 24 00:00:00 EDT 2022
Alpha-synuclein/MPP+ mediated activation of NLRP3 inflammasome through microtubule-driven mitochondrial perinuclear transport.
Biochemical and biophysical research communications
Yang X,Ma H,Yv Q,Ye F,He Z,Chen S,Keram A,Li W,Zhu M
Sat Feb 26 00:00:00 EST 2022
Alpha-synuclein/MPP+ mediated activation of NLRP3 inflammasome through microtubule-driven mitochondrial perinuclear transport.
Biochemical and biophysical research communications
Yang X,Ma H,Yv Q,Ye F,He Z,Chen S,Keram A,Li W,Zhu M
Sat Feb 26 00:00:00 EST 2022
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.
Cell reports. Medicine
Singh A,D'Amico D,Andreux PA,Fouassier AM,Blanco-Bose W,Evans M,Aebischer P,Auwerx J,Rinsch C
Tue May 17 00:00:00 EDT 2022
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Frontiers in immunology
Shi B,Hao Y,Li W,Dong H,Xu M,Gao P
Thu May 19 00:00:00 EDT 2022
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Immunology
Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y
Tue Nov 01 00:00:00 EDT 2022
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Immunology
Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y
Tue Nov 01 00:00:00 EDT 2022
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Immunology
Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y
Tue Nov 01 00:00:00 EDT 2022
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Immunology
Chen X,Zhao Q,Xu Y,Wu Q,Zhang R,Du Q,Miao Y,Zuo Y,Zhang HG,Huang F,Ren T,He J,Qiao C,Li Y,Li S,Xu Y,Wu D,Yu Z,Lv H,Wang J,Zheng H,Yuan Y
Tue Nov 01 00:00:00 EDT 2022
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Veterinary microbiology
Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J
Tue Mar 01 00:00:00 EST 2022
METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability.
Nucleic acids research
Chen L,Zhang C,Ma W,Huang J,Zhao Y,Liu H
Fri Nov 11 00:00:00 EST 2022
Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice.
Frontiers in cardiovascular medicine
Ren KW,Yu XH,Gu YH,Xie X,Wang Y,Wang SH,Li HH,Bi HL
Sat Oct 29 00:00:00 EDT 2022
Peripheral Transplantation of Mesenchymal Stem Cells at Sepsis Convalescence Improves Cognitive Function of Sepsis Surviving Mice.
Oxidative medicine and cellular longevity
Tan L,Cheng Y,Wang H,Tong J,Qin X
Wed Oct 05 00:00:00 EDT 2022
Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function.
Neural regeneration research
Wu MY,Zou WJ,Yu P,Yang Y,Li SJ,Liu Q,Xie J,Chen SQ,Lin WJ,Tang Y
Sat Oct 01 00:00:00 EDT 2022
Worenine Prevents Solar Ultraviolet-Induced Sunburn by Inhibiting JNK2.
Frontiers in pharmacology
Xiao J,Lu H,Ma T,Ni X,Chang T,Liu M,Li N,Lu P,Ke C,Tian Q,Zou L,Wang F,Wang W,Zhang L,Yuan P,Liu L,Zhang J,Shi F,Duan Q,Zhu F
Fri Aug 19 00:00:00 EDT 2022
Hexokinase 1 cellular localization regulates the metabolic fate of glucose.
Molecular cell
De Jesus A,Keyhani-Nejad F,Pusec CM,Goodman L,Geier JA,Stoolman JS,Stanczyk PJ,Nguyen T,Xu K,Suresh KV,Chen Y,Rodriguez AE,Shapiro JS,Chang HC,Chen C,Shah KP,Ben-Sahra I,Layden BT,Chandel NS,Weinberg SE,Ardehali H
Thu Apr 07 00:00:00 EDT 2022
DNA methylation status of DNAJA4 is essential for human erythropoiesis.
Epigenomics
Zhang H,Xue F,Zhao H,Chen L,Wang T,Wu X
Sat Oct 01 00:00:00 EDT 2022
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
Molecular cell
Zhou Q,Hao B,Cao X,Gao L,Yu Z,Zhao Y,Zhu M,Zhong G,Chi F,Dai X,Mao J,Zhu Y,Rong P,Chen L,Bai X,Ye C,Chen S,Liang T,Li L,Feng XH,Tan M,Zhao B
Thu Dec 15 00:00:00 EST 2022
The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma.
Frontiers in cell and developmental biology
Parkinson LM,Gillen SL,Woods LM,Chaytor L,Marcos D,Ali FR,Carroll JS,Philpott A
Wed Mar 08 00:00:00 EST 2023
DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.
Cell death & disease
Wang YL,Zhao WW,Bai SM,Ma Y,Yin XK,Feng LL,Zeng GD,Wang F,Feng WX,Zheng J,Wang YN,Zeng B,Liu Q,Hung MC,Wan XB
Tue Aug 16 00:00:00 EDT 2022
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
International journal of molecular sciences
Cao Y,Zhang M,Li Y,Lu J,Zhou W,Li X,Shi H,Xu B,Li S
Tue Nov 22 00:00:00 EST 2022
Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers.
Cell & bioscience
Bai L,Tu WY,Xiao Y,Zhang K,Shen C
Tue Aug 30 00:00:00 EDT 2022
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Biochemical and biophysical research communications
Wang KX,Yan C,Yang X,Zhu PY,Cui WW,Ye C,Hu K,Lan T,Huang LY,Wang W,Ma P,Qi SH,Gu B,Luo L
Sat Jun 18 00:00:00 EDT 2022
Trehalose prevents glyphosate-induced testicular damage in roosters via its antioxidative properties.
Research in veterinary science
Chen K,Liu JB,Tie CZ,Wang L
Tue Dec 20 00:00:00 EST 2022
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Biochimica et biophysica acta. Molecular cell research
Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L
Tue Feb 01 00:00:00 EST 2022
Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.
Epilepsia
Lin JR,Cheng JF,Liu YT,Hsu TR,Lin KM,Chen C,Lin CL,Tsai MH,Tsai JW
Sun May 01 00:00:00 EDT 2022
Novel lissencephaly-associated DCX variants in the C-terminal DCX domain affect microtubule binding and dynamics.
Epilepsia
Lin JR,Cheng JF,Liu YT,Hsu TR,Lin KM,Chen C,Lin CL,Tsai MH,Tsai JW
Sun May 01 00:00:00 EDT 2022
H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.
Nucleic acids research
Li Z,Zhang X,Xie S,Liu X,Fei C,Huang X,Tang Y,Zhou LQ
Fri Jul 08 00:00:00 EDT 2022
Damage of uremic myocardium by p-cresyl sulfate and the ameliorative effect of Klotho by regulating SIRT6 ubiquitination.
Toxicology letters
Chen C,Xie C,Xiong Y,Wu H,Wu L,Zhu J,Xing C,Mao H
Mon Aug 15 00:00:00 EDT 2022
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
International journal of molecular sciences
Lan T,Zhang K,Lin F,He Q,Wu S,Xu Z,Zhang Y,Quan F
Wed Aug 03 00:00:00 EDT 2022
RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.
Science advances
Ma P,Wan LP,Li Y,He CH,Song NN,Zhao S,Wang H,Ding YQ,Mao B,Sheng N
Fri Sep 30 00:00:00 EDT 2022
Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.
Frontiers in pharmacology
Tan Z,Si Y,Yu Y,Ding J,Huang L,Xu Y,Zhang H,Lu Y,Wang C,Yu B,Yuan L
Sat Jul 16 00:00:00 EDT 2022
Metformin alleviates the cognitive impairment caused by aluminum by improving energy metabolism disorders in mice.
Biochemical pharmacology
Song Y,Liu Z,Zhu X,Hao C,Hao W,Wu S,Yang J,Lu X,Jin C
Mon Aug 01 00:00:00 EDT 2022
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
The EMBO journal
Gruijs da Silva LA,Simonetti F,Hutten S,Riemenschneider H,Sternburg EL,Pietrek LM,Gebel J,Dötsch V,Edbauer D,Hummer G,Stelzl LS,Dormann D
Tue Apr 19 00:00:00 EDT 2022
TRIM67 Suppresses TNFalpha-Triggered NF-kB Activation by Competitively Binding Beta-TrCP to IkBa.
Frontiers in immunology
Fan W,Liu X,Zhang J,Qin L,Du J,Li X,Qian S,Chen H,Qian P
Mon May 02 00:00:00 EDT 2022
MicroRNA-223-3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1).
Toxicology
Zhao S,Tan Y,Qin J,Xu H,Liu L,Wan H,Zhang C,Fan W,Qu S
Thu Jun 30 00:00:00 EDT 2022
HIF-1α upregulation exerts the antagonistic effect against angiogenesis inhibition in manganese deficiency-induced tibial dyschondroplasia of broiler chicks.
Veterinary research communications
Lu L,Jin C,Dong PF,Wang ZY
Thu Dec 01 00:00:00 EST 2022
The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.
The Journal of cell biology
Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E
Mon Dec 05 00:00:00 EST 2022
The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.
The Journal of cell biology
Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E
Mon Dec 05 00:00:00 EST 2022
Camptothecin compromises transcription recovery and cell survival against cisplatin and ultraviolet irradiation regardless of transcription-coupled nucleotide excision repair.
DNA repair
Sakasai R,Wakasugi M,Matsui T,Sunatani Y,Saijo M,Matsunaga T,Iwabuchi K
Sun May 01 00:00:00 EDT 2022
Seneca Valley Virus Induces DHX30 Cleavage to Antagonize Its Antiviral Effects.
Journal of virology
Wen W,Zheng Z,Wang H,Zhao Q,Yin M,Chen H,Li X,Qian P
Wed Sep 14 00:00:00 EDT 2022
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Oxidative medicine and cellular longevity
Chen P,Yang J,Wu N,Han B,Kastelic JP,Gao J
Fri Mar 18 00:00:00 EDT 2022
Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity.
Molecular cell
Li Y,Huang J,Zhu J,Bao L,Wang H,Jiang Y,Tian K,Wang R,Zheng H,Duan W,Lai W,Yi X,Zhu Y,Guo T,Ji X
Thu Oct 20 00:00:00 EDT 2022
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
EMBO reports
Song P,Yang W,Lou KF,Dong H,Zhang H,Wang B,Chen D
Mon Nov 07 00:00:00 EST 2022
Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.
Pharmacological research
Sun X,Xiao H,Li S,Chen R,Lin Z,Yang Y,Chen Z,Deng L,Huang H
Tue Feb 01 00:00:00 EST 2022
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Biochemical pharmacology
Yang Y,Xiao H,Lin Z,Chen R,Li S,Li C,Sun X,Hei Z,Gong W,Huang H
Thu Dec 01 00:00:00 EST 2022
Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation.
Open biology
Xue J,Liao Q,Luo M,Hua C,Zhao J,Yu G,Chen X,Li X,Zhang X,Ran R,Lu F,Wang Y,Qiao L
Fri Apr 01 00:00:00 EDT 2022
Curcumae Radix Decreases Neurodegenerative Markers through Glycolysis Decrease and TCA Cycle Activation.
Nutrients
Jo SL,Yang H,Lee SR,Heo JH,Lee HW,Hong EJ
Mon Apr 11 00:00:00 EDT 2022
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Redox biology
Xu Z,Xu J,Sun S,Lin W,Li Y,Lu Q,Li F,Yang Z,Lu Y,Liu W
Mon Aug 01 00:00:00 EDT 2022
Cell cycle arrest induced by trichoplein depletion is independent of cilia assembly.
Journal of cellular physiology
Huang M,Kong X,Tang Z,Lin Z,He R,Cao M,Zhang X
Wed Jun 01 00:00:00 EDT 2022
Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine.
Frontiers in pharmacology
Huang PP,Zhu WQ,Xiao JM,Zhang YQ,Li R,Yang Y,Shen L,Luo F,Dai W,Lian PA,Tang YX,Ran JL,Huang XS
Tue Aug 30 00:00:00 EDT 2022
The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Cheng G,Zhang S,Lv M,Qi C,Fan R,Guo X,Liu J,Zhao X
Mon Aug 01 00:00:00 EDT 2022
Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.
International immunopharmacology
Liu W,Liu M,Xiong H,Xia L,Yang Q,Chen M,Cai Y,Li S
Thu Dec 01 00:00:00 EST 2022
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Frontiers in oncology
Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P
Sat May 07 00:00:00 EDT 2022
Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway.
Scientific reports
Zhu W,Ding C,Huang P,Ran J,Lian P,Tang Y,Dai W,Huang X
Mon Apr 04 00:00:00 EDT 2022
Inhibition of CK2 Reduces NG2 Expression in Juvenile Angiofibroma.
Biomedicines
Boewe AS,Wemmert S,Kulas P,Schick B,Götz C,Wrublewsky S,Montenarh M,Menger MD,Laschke MW,Ampofo E
Thu Apr 21 00:00:00 EDT 2022
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.
iScience
Vabret N,Najburg V,Solovyov A,Gopal R,McClain C,Šulc P,Balan S,Rahou Y,Beauclair G,Chazal M,Varet H,Legendre R,Sismeiro O,Sanchez David RY,Chauveau L,Jouvenet N,Markowitz M,van der Werf S,Schwartz O,Tangy F,Bhardwaj N,Greenbaum BD,Komarova AV
Fri Jul 15 00:00:00 EDT 2022
N6-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming.
Theranostics
Zhang K,Zhang T,Yang Y,Tu W,Huang H,Wang Y,Chen Y,Pan K,Chen Z
Fri Jul 15 00:00:00 EDT 2022
iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation.
Oncogene
Zhao D,Zheng S,Wang X,Liu H,Zhao K,Li L,Hu Y
Tue Mar 01 00:00:00 EST 2022
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.
Cell research
Hu CL,Chen BY,Li Z,Yang T,Xu CH,Yang R,Yu PC,Zhao J,Liu T,Liu N,Shan B,Zhang Q,Song J,Fei MY,Zong LJ,Zhang JY,Wu JC,Chen SB,Wang Y,Chang B,Hou D,Liu P,Jiang Y,Li X,Chen X,Deng CH,Ren YY,Wang R,Jin J,Xue K,Zhang Y,Du M,Shi J,Wu LY,Chang CK,Shen S,Chen Z,Chen SJ,Liu X,Sun XJ,Zheng M,Wang L
Thu Dec 01 00:00:00 EST 2022
A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology.
Nature cell biology
Zhou J,Duan M,Wang X,Zhang F,Zhou H,Ma T,Yin Q,Zhang J,Tian F,Wang G,Yang C
Fri Apr 01 00:00:00 EDT 2022
Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.
International immunopharmacology
Chen X,Wu Q,Cao X,Yang Y,Gong Z,Ren T,Du Q,Yuan Y,Zuo Y,Miao Y,He J,Qiao C,Zheng Z,Zhang T,Xu Y,Wu D,Wang Q,Huang L,Xie Z,Lv H,Wang J,Gong F,Liu Z,Wen C,Zheng H
Tue Nov 01 00:00:00 EDT 2022
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Journal of experimental & clinical cancer research : CR
Yang W,Li J,Zhang M,Yu H,Zhuang Y,Zhao L,Ren L,Gong J,Bi H,Zeng L,Xue Y,Yang J,Zhao Y,Wang S,Gao S,Fu Z,Li D,Zhang J,Wang T,Shan M,Tang B,Li X
Fri Feb 18 00:00:00 EST 2022
Splicing factor BUD31 promotes ovarian cancer progression through sustaining the expression of anti-apoptotic BCL2L12.
Nature communications
Wang Z,Wang S,Qin J,Zhang X,Lu G,Liu H,Guo H,Wu L,Shender VO,Shao C,Kong B,Liu Z
Fri Oct 21 00:00:00 EDT 2022
ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.
Cell biology international
Li Y,Tang J,Li J,Du Y,Bai F,Yang L,Li X,Jin X,Wang T
Wed Jun 01 00:00:00 EDT 2022
Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors.
eLife
Kim SJ,Woo Y,Kim HJ,Goo BS,Nhung TTM,Lee SA,Suh BK,Mun DJ,Kim JH,Park SK
Mon Apr 25 00:00:00 EDT 2022
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhou Y,Lu Q
Thu Sep 01 00:00:00 EDT 2022
Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.
Nature communications
Yuan K,Li Z,Kuang W,Wang X,Ji M,Chen W,Ding J,Li J,Min W,Sun C,Ye X,Lu M,Wang L,Ge H,Jiang Y,Hao H,Xiao Y,Yang P
Wed May 25 00:00:00 EDT 2022
Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling.
Particle and fibre toxicology
Ribeiro LW,Pietri M,Ardila-Osorio H,Baudry A,Boudet-Devaud F,Bizingre C,Arellano-Anaya ZE,Haeberlé AM,Gadot N,Boland S,Devineau S,Bailly Y,Kellermann O,Bencsik A,Schneider B
Fri Jul 15 00:00:00 EDT 2022
PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK.
Cells
Zi J,Xu J,Luo J,Yang X,Zhen Z,Li X,Hu D,Guo Y,Guo H,Ding X,Zhang L
Tue Oct 11 00:00:00 EDT 2022
DELE1 tracks perturbed protein import and processing in human mitochondria.
Nature communications
Fessler E,Krumwiede L,Jae LT
Wed Apr 06 00:00:00 EDT 2022
Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis.
Nature communications
Wang Z,Sun Y,Lou F,Bai J,Zhou H,Cai X,Sun L,Yin Q,Tang S,Wu Y,Fan L,Xu Z,Wang H,Hu X,Wang H
Mon Dec 19 00:00:00 EST 2022
Expression pattern of alkB homolog 5 in goat testis and its role in spermatogonial stem cells.
Cell and tissue research
Liu Z,Cai Y,Deng M,Li D,Leng Q,Shi L,Tang Y,Wang F,Wan Y
Sat Jan 01 00:00:00 EST 2022
Solamargine Alleviated UVB-Induced Inflammation and Melanogenesis in Human Keratinocytes and Melanocytes via the p38 MAPK Signaling Pathway, a Promising Agent for Post-inflammatory Hyperpigmentation.
Frontiers in medicine
Zhao J,Dan Y,Liu Z,Wang Q,Jiang M,Zhang C,Sheu HM,Lin CS,Xiang L
Sat Jul 16 00:00:00 EDT 2022
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.
iScience
Magusto J,Beaupère C,Afonso MB,Auclair M,Delaunay JL,Soret PA,Courtois G,Aït-Slimane T,Housset C,Jéru I,Fève B,Ratziu V,Rodrigues CMP,Gautheron J
Fri Oct 21 00:00:00 EDT 2022
6-O-desulfated heparin attenuates myocardial ischemia/reperfusion injury in mice through the regulation of miR-199a-5p/klotho axis.
Glycoconjugate journal
Wang Y,Li T,Li N,Huang C,Xiong X,Xie X,Wu M,Wang L,Jiang J
Thu Dec 01 00:00:00 EST 2022
Identification and Characterization of BmNPV m6A Sites and Their Possible Roles During Viral Infection.
Frontiers in immunology
Zhang X,Zhang Y,Pan J,Gong C,Hu X
Fri Apr 08 00:00:00 EDT 2022
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress.
Frontiers in oncology
Han T,Tong J,Wang M,Gan Y,Gao B,Chen J,Liu Y,Hao Q,Zhou X
Sat Jul 16 00:00:00 EDT 2022
Osteopontin is required for the maintenance of leukemia stem cells in acute myeloid leukemia.
Biochemical and biophysical research communications
Zhou J,Chen X,Zhou P,Sun X,Chen Y,Li M,Chu Y,Zhou J,Hu X,Luo Y,Yuan W,Wang G
Sat Apr 16 00:00:00 EDT 2022
Hippocampal overexpression of TREM2 ameliorates high fat diet induced cognitive impairment and modulates phenotypic polarization of the microglia.
Genes & diseases
Wu M,Liao M,Huang R,Chen C,Tian T,Wang H,Li J,Li J,Sun Y,Wu C,Li Q,Xiao X
Tue Mar 01 00:00:00 EST 2022
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.
Autophagy
Lee JE,Kim N,Jung M,Mun JY,Yoo JY
Fri Jul 01 00:00:00 EDT 2022
Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis.
Annals of translational medicine
Wu F,Yuan X,Liu W,Meng L,Li X,Gao X,Zhou S,Fang L,Yu D
Sun May 01 00:00:00 EDT 2022
Construction of Artificial Ovaries with Decellularized Porcine Scaffold and Its Elicited Immune Response after Xenotransplantation in Mice.
Journal of functional biomaterials
Wu T,Gao YY,Tang XN,Zhang JJ,Wang SX
Wed Sep 28 00:00:00 EDT 2022
BmCPV-Derived Circular DNA vcDNA-S7 Mediated by Bombyx mori Reverse Transcriptase (RT) Regulates BmCPV Infection.
Frontiers in immunology
Zhu M,Pan J,Tong X,Qiu Q,Zhang X,Zhang Y,Sun S,Feng Y,Xue R,Cao G,Hu X,Gong C
Fri Apr 08 00:00:00 EDT 2022
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Frontiers in pharmacology
Gu YH,Ren KW,Wang Y,Wang SH,Yu XH,Xu LW,Li HH,Bi HL
Fri Nov 18 00:00:00 EST 2022
Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.
Biochemical and biophysical research communications
Huang XT,Zheng Y,Long G,Peng WT,Wan QQ
Thu Jun 30 00:00:00 EDT 2022
Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.
Functional & integrative genomics
Xiong Y,Song X,Zu X,Chen M,He W,Qi L
Sat Oct 01 00:00:00 EDT 2022
Resveratrol Synergistically Promotes BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells.
Stem cells international
Wang Y,Xia C,Chen Y,Jiang T,Hu Y,Gao Y
Fri Aug 05 00:00:00 EDT 2022
Momordica. charantia-Derived Extracellular Vesicles-Like Nanovesicles Protect Cardiomyocytes Against Radiation Injury via Attenuating DNA Damage and Mitochondria Dysfunction.
Frontiers in cardiovascular medicine
Cui WW,Ye C,Wang KX,Yang X,Zhu PY,Hu K,Lan T,Huang LY,Wang W,Gu B,Yan C,Ma P,Qi SH,Luo L
Sat May 07 00:00:00 EDT 2022
Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification.
Journal of translational medicine
Lyu F,Li Y,Yan Z,He Q,Cheng L,Zhang P,Liu B,Liu C,Song Y,Xing Y
Tue May 10 00:00:00 EDT 2022
Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Cell reports
Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB
Tue Apr 12 00:00:00 EDT 2022
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Environmental toxicology
Hao W,Zhu X,Liu Z,Song Y,Wu S,Lu X,Yang J,Jin C
Wed Jun 01 00:00:00 EDT 2022
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Frontiers in immunology
Li L,Chen X,Lv M,Cheng Z,Liu F,Wang Y,Zhou A,Liu J,Zhao X
Tue Jul 19 00:00:00 EDT 2022
Ajuba functions as a co-activator of C/EBPβ to induce expression of PPARγ and C/EBPα during adipogenesis.
Molecular and cellular endocrinology
Yan H,Li Q,Li M,Zou X,Bai N,Yu Z,Zhang J,Zhang D,Zhang Q,Wang J,Jia H,Wu Y,Hou Z
Sat Jan 01 00:00:00 EST 2022
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export.
Molecular brain
Nakashima N,Nakashima A,Nakashima K,Takano M
Fri Nov 04 00:00:00 EDT 2022
Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome.
Nature genetics
Cousin MA,Creighton BA,Breau KA,Spillmann RC,Torti E,Dontu S,Tripathi S,Ajit D,Edwards RJ,Afriyie S,Bay JC,Harper KM,Beltran AA,Munoz LJ,Falcon Rodriguez L,Stankewich MC,Person RE,Si Y,Normand EA,Blevins A,May AS,Bier L,Aggarwal V,Mancini GMS,van Slegtenhorst MA,Cremer K,Becker J,Engels H,Aretz S,MacKenzie JJ,Brilstra E,van Gassen KLI,van Jaarsveld RH,Oegema R,Parsons GM,Mark P,Helbig I,McKeown SE,Stratton R,Cogne B,Isidor B,Cacheiro P,Smedley D,Firth HV,Bierhals T,Kloth K,Weiss D,Fairley C,Shieh JT,Kritzer A,Jayakar P,Kurtz-Nelson E,Bernier RA,Wang T,Eichler EE,van de Laar IMBH,McConkie-Rosell A,McDonald MT,Kemppainen J,Lanpher BC,Schultz-Rogers LE,Gunderson LB,Pichurin PN,Yoon G,Zech M,Jech R,Winkelmann J,Beltran AS,Zimmermann MT,Temple B,Moy SS,Klee EW,Tan QK,Lorenzo DN
Thu Jul 01 00:00:00 EDT 2021
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.
Neuron
Wang C,Xiong M,Gratuze M,Bao X,Shi Y,Andhey PS,Manis M,Schroeder C,Yin Z,Madore C,Butovsky O,Artyomov M,Ulrich JD,Holtzman DM
Wed May 19 00:00:00 EDT 2021
Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases.
Proceedings of the National Academy of Sciences of the United States of America
De Cesare V,Carbajo Lopez D,Mabbitt PD,Fletcher AJ,Soetens M,Antico O,Wood NT,Virdee S
Tue Jan 26 00:00:00 EST 2021
NR1D1 Deletion Induces Rupture-Prone Vulnerable Plaques by Regulating Macrophage Pyroptosis via the NF-κB/NLRP3 Inflammasome Pathway.
Oxidative medicine and cellular longevity
Wu Z,Liao F,Luo G,Qian Y,He X,Xu W,Ding S,Pu J
Thu Mar 03 00:00:00 EST 2022
NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma.
Oxidative medicine and cellular longevity
Su X,Yang Y,Guo C,Zhang R,Sun S,Wang Y,Qiao Q,Fu Y,Pang Q
Wed Jan 05 00:00:00 EST 2022
Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor.
Development (Cambridge, England)
Otsu K,Ida-Yonemochi H,Ikezaki S,Ema M,Hitomi J,Ohshima H,Harada H
Mon Feb 15 00:00:00 EST 2021
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.
Life science alliance
Redl E,Sheibani-Tezerji R,Cardona CJ,Hamminger P,Timelthaler G,Hassler MR,Zrimšek M,Lagger S,Dillinger T,Hofbauer L,Draganić K,Tiefenbacher A,Kothmayer M,Dietz CH,Ramsahoye BH,Kenner L,Bock C,Seiser C,Ellmeier W,Schweikert G,Egger G
Mon Feb 01 00:00:00 EST 2021
The translational repressor 4E-BP1 regulates RRM2 levels and functions as a tumor suppressor in Ewing sarcoma tumors.
Oncogene
Goss KL,Koppenhafer SL,Waters T,Terry WW,Wen KK,Wu M,Ostergaard J,Gordon PM,Gordon DJ
Fri Jan 01 00:00:00 EST 2021
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Journal of physiology and biochemistry
Li Y,Zhao Y,Li Y,Zhang X,Li C,Long N,Chen X,Bao L,Zhou J,Xie Y
Mon Feb 01 00:00:00 EST 2021
Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells.
Bioactive materials
Zhang Y,Elechalawar CK,Hossen MN,Francek ER,Dey A,Wilhelm S,Bhattacharya R,Mukherjee P
Mon Feb 01 00:00:00 EST 2021
EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development.
Investigative ophthalmology & visual science
Cao X,An J,Cao Y,Lv J,Wang J,Ding Y,Lin X,Zhou X
Mon Feb 01 00:00:00 EST 2021
ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.
Cell death & disease
Zhang W,Zhang R,Zeng Y,Li Y,Chen Y,Zhou J,Zhang Y,Wang A,Zhu J,Liu Z,Yan Z,Huang JA
Sat Jul 31 00:00:00 EDT 2021
Hypoxia regulates overall mRNA homeostasis by inducing Met1-linked linear ubiquitination of AGO2 in cancer cells.
Nature communications
Zhang H,Zhao X,Guo Y,Chen R,He J,Li L,Qiang Z,Yang Q,Liu X,Huang C,Lu R,Fang J,Cao Y,Huang J,Wang Y,Huang J,Chen GQ,Cheng J,Yu J
Mon Sep 13 00:00:00 EDT 2021
NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation.
American journal of cancer research
Fan XJ,Wang YL,Zhao WW,Bai SM,Ma Y,Yin XK,Feng LL,Feng WX,Wang YN,Liu Q,Hung MC,Wan XB
Tue Jul 13 00:00:00 EDT 2021
LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.
Redox biology
Wei WS,Wang N,Deng MH,Dong P,Liu JY,Xiang Z,Li XD,Li ZY,Liu ZH,Peng YL,Li Z,Jiang LJ,Yao K,Ye YL,Lu WH,Zhang ZL,Zhou FJ,Liu ZW,Xie D,Yu CP
Sat Nov 27 00:00:00 EST 2021
Ribonucleic Acid Export 1 Is a Kinetochore-Associated Protein That Participates in Chromosome Alignment in Mouse Oocytes.
International journal of molecular sciences
Chen F,Jiao XF,Meng F,Wang YS,Ding ZM,Miao YL,Xiong JJ,Huo LJ
Mon May 03 00:00:00 EDT 2021
Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis.
Molecular neurobiology
Otsuka S,Setoyama K,Takada S,Nakanishi K,Terashi T,Norimatsu K,Tani A,Sakakima H,Maruyama I,Tancharoen S,Tanaka E,Kikuchi K
Mon Nov 01 00:00:00 EDT 2021
In vitro and in vivo synergistic anti-tumor effect of LIN28 inhibitor and metformin in oral squamous cell carcinoma.
European journal of pharmacology
Chen H,Sa G,Li L,He S,Wu T
Fri Jan 15 00:00:00 EST 2021
ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.
Cellular signalling
Cao C,He K,Li S,Ge Q,Liu L,Zhang Z,Zhang H,Wang X,Sun X,Ding L
Wed Sep 01 00:00:00 EDT 2021
Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3.
Autophagy
Wen W,Li X,Yin M,Wang H,Qin L,Li H,Liu W,Zhao Z,Zhao Q,Chen H,Hu J,Qian P
Mon Nov 01 00:00:00 EDT 2021
ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer.
Journal of experimental & clinical cancer research : CR
Sun X,He Z,Guo L,Wang C,Lin C,Ye L,Wang X,Li Y,Yang M,Liu S,Hua X,Wen W,Lin C,Long Z,Zhang W,Li H,Jian Y,Zhu Z,Wu X,Lin H
Fri Apr 30 00:00:00 EDT 2021
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Cell metabolism
Liu Y,Liang G,Xu H,Dong W,Dong Z,Qiu Z,Zhang Z,Li F,Huang Y,Li Y,Wu J,Yin S,Zhang Y,Guo P,Liu J,Xi JJ,Jiang P,Han D,Yang CG,Xu MM
Tue Jun 01 00:00:00 EDT 2021
Disrupted-in-schizophrenia 1 enhances the quality of circadian rhythm by stabilizing BMAL1.
Translational psychiatry
Lee SB,Park J,Kwak Y,Park YU,Nhung TTM,Suh BK,Woo Y,Suh Y,Cho E,Cho S,Park SK
Thu Feb 04 00:00:00 EST 2021
Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer.
Cancer immunology, immunotherapy : CII
Liu Y,Huang Z,Wei Y,Zhang M,Li X,Yang S,Wang H
Mon Feb 01 00:00:00 EST 2021
Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.
Aging
Peng Y,Zhang Z,Zhang A,Liu C,Sun Y,Peng Z,Liu Y
Wed Mar 24 00:00:00 EDT 2021
PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons.
Neurochemistry international
Marcus JM,Hossain MI,Gagné JP,Poirier GG,McMahon LL,Cowell RM,Andrabi SA
Wed Sep 01 00:00:00 EDT 2021
Kindlin-2 Acts as a Key Mediator of Lung Fibroblast Activation and Pulmonary Fibrosis Progression.
American journal of respiratory cell and molecular biology
Zhang P,Wang J,Luo W,Yuan J,Cui C,Guo L,Wu C
Thu Jul 01 00:00:00 EDT 2021
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Molecular cancer research : MCR
Wang Q,Wu H,Hu J,Fu H,Qu Y,Yang Y,Cai KQ,Efimov A,Wu M,Yen T,Wang Y,Yang ZJ
Fri Oct 01 00:00:00 EDT 2021
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells.
Molecular cancer research : MCR
Wang Q,Wu H,Hu J,Fu H,Qu Y,Yang Y,Cai KQ,Efimov A,Wu M,Yen T,Wang Y,Yang ZJ
Fri Oct 01 00:00:00 EDT 2021
Snail enhances arginine synthesis by inhibiting ubiquitination-mediated degradation of ASS1.
EMBO reports
Jia H,Yang Y,Li M,Chu Y,Song H,Zhang J,Zhang D,Zhang Q,Xu Y,Wang J,Xu H,Zou X,Peng H,Hou Z
Wed Aug 04 00:00:00 EDT 2021
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation.
Cell death & disease
Xu L,Xu W,Li D,Yu X,Gao F,Qin Y,Yang Y,Zhao S
Mon Aug 09 00:00:00 EDT 2021
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Nature communications
Barroso-Gomila O,Trulsson F,Muratore V,Canosa I,Merino-Cacho L,Cortazar AR,Pérez C,Azkargorta M,Iloro I,Carracedo A,Aransay AM,Elortza F,Mayor U,Vertegaal ACO,Barrio R,Sutherland JD
Thu Nov 18 00:00:00 EST 2021
NLRP3 inflammasome of renal tubular epithelial cells induces kidney injury in acute hemolytic transfusion reactions.
Clinical and translational medicine
Liu Z,Chen Y,Niu B,Yin D,Feng F,Gu S,An Q,Xu J,An N,Zhang J,Yi J,Yin W,Qin X,Hu X
Mon Mar 01 00:00:00 EST 2021
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Biochemical pharmacology
Sun XH,Xiao HM,Zhang M,Lin ZY,Yang Y,Chen R,Liu PQ,Huang KP,Huang HQ
Tue Jun 01 00:00:00 EDT 2021
Antibody Self-Assembly Maximizes Cytoplasmic Immunostaining Accuracy of Compact Quantum Dots.
Chemistry of materials : a publication of the American Chemical Society
Ma L,Geng J,Kolossov VL,Han Z,Pei Y,Lim SJ,Kilian KA,Smith AM
Tue Jul 13 00:00:00 EDT 2021
Embryonic stem cell-derived extracellular vesicles promote the recovery of kidney injury.
Stem cell research & therapy
Yu L,Liu S,Wang C,Zhang C,Wen Y,Zhang K,Chen S,Huang H,Liu Y,Wu L,Han Z,Chen X,Li Z,Liu N
Fri Jul 02 00:00:00 EDT 2021
HSV-1-encoded ICP0 degrades the host deubiquitinase BRCC36 to antagonize interferon antiviral response.
Molecular immunology
Zhang L,Huang F,Liu J,Xu Y,Miao Y,Yuan Y,Chen X,Zhang HG,Wang J,Zheng H,Zuo Y
Thu Jul 01 00:00:00 EDT 2021
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
Cancer gene therapy
Liu Y,Wang Y,Liu J,Kang R,Tang D
Mon Feb 01 00:00:00 EST 2021
Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients.
Journal of experimental & clinical cancer research : CR
Belluti S,Semeghini V,Rigillo G,Ronzio M,Benati D,Torricelli F,Reggiani Bonetti L,Carnevale G,Grisendi G,Ciarrocchi A,Dominici M,Recchia A,Dolfini D,Imbriano C
Mon Nov 15 00:00:00 EST 2021
UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.
Molecular oncology
Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y
Wed Dec 01 00:00:00 EST 2021
UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.
Molecular oncology
Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y
Wed Dec 01 00:00:00 EST 2021
Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy.
Aging
Shen Z,Ji K,Cai Z,Huang C,He X,Xu H,Chen G
Fri Mar 19 00:00:00 EDT 2021
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Frontiers in cardiovascular medicine
Zhuang L,Mao Y,Liu Z,Li C,Jin Q,Lu L,Tao R,Yan X,Chen K
Tue Aug 31 00:00:00 EDT 2021
The transcription factor NF-Y participates to stem cell fate decision and regeneration in adult skeletal muscle.
Nature communications
Rigillo G,Basile V,Belluti S,Ronzio M,Sauta E,Ciarrocchi A,Latella L,Saclier M,Molinari S,Vallarola A,Messina G,Mantovani R,Dolfini D,Imbriano C
Thu Oct 14 00:00:00 EDT 2021
Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9+ cells to prevent the development of liver cancer in a mouse model.
Stem cell research & therapy
Chen M,Lu C,Lu H,Zhang J,Qin D,Liu S,Li X,Zhang L
Mon Apr 12 00:00:00 EDT 2021
Proteomic analysis of the exosomes secreted from Ctenopharyngodon idellus kidney cells infected with grass carp reovirus reveals their involvement in the cellular responses to viral infection.
Fish physiology and biochemistry
Zhang X,Zhang Y,Pan J,Zhu M,Liang Z,Shen Z,Dai K,Yan B,Dai Y,Xue R,Cao G,Hu X,Gong C
Sun Aug 01 00:00:00 EDT 2021
SLC25A21 Suppresses Cell Growth in Bladder Cancer via an Oxidative Stress-Mediated Mechanism.
Frontiers in oncology
Wang Y,Gao J,Hu S,Zeng W,Yang H,Chen H,Wang S
Wed Apr 27 00:00:00 EDT 2022
FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation.
Cell death & disease
Liu X,Ge J,Chen C,Shen Y,Xie J,Zhu X,Liu M,Hu J,Chen L,Guo L,Zhou Q,Yan X,Qiu Y,Wan R,Marian AJ,Hong K
Tue Jan 05 00:00:00 EST 2021
Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANASIM-Associated Proteins in Hypoxia.
mSystems
Liu X,Gan J,Du S,Zhu C,Wang Y,Jia Y,Zhang D,Qu D,Wei F,Robertson ES,Cai Q
Tue Dec 21 00:00:00 EST 2021
Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANASIM-Associated Proteins in Hypoxia.
mSystems
Liu X,Gan J,Du S,Zhu C,Wang Y,Jia Y,Zhang D,Qu D,Wei F,Robertson ES,Cai Q
Tue Dec 21 00:00:00 EST 2021
SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation.
Theranostics
Guan C,Huang X,Yue J,Xiang H,Shaheen S,Jiang Z,Tao Y,Tu J,Liu Z,Yao Y,Yang W,Hou Z,Liu J,Yang XD,Zou Q,Su B,Liu Z,Ni J,Cheng J,Wu X
Thu Jul 29 00:00:00 EDT 2021
N6-methyladenosine regulates ATM expression and downstream signaling.
Journal of Cancer
Zhang X,Liu P,Zheng X,Wang J,Peng Q,Li Z,Wei L,Liu C,Wu Y,Wen Y,Yan Q,Ma J
Fri Nov 05 00:00:00 EDT 2021
Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.
Journal of Cancer
Chen L,Yi C,Li W,Tseng Y,Zhang J,Liu J
Tue Jan 05 00:00:00 EST 2021
Discovery of a novel AR/HDAC6 dual inhibitor for prostate cancer treatment.
Aging
Zhou M,Zheng H,Li Y,Huang H,Min X,Dai S,Zhou W,Chen Z,Xu G,Chen Y
Wed Feb 17 00:00:00 EST 2021
MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Development (Cambridge, England)
Wang X,Wen Y,Zhang J,Swanson G,Guo S,Cao C,Krawetz SA,Zhang Z,Yuan S
Thu Apr 01 00:00:00 EDT 2021
OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells.
Pathology, research and practice
Ge X,Peng X,Li M,Ji F,Chen J,Zhang D
Wed Sep 01 00:00:00 EDT 2021
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Journal of experimental & clinical cancer research : CR
Liu S,Chen L,Chen H,Xu K,Peng X,Zhang M
Fri Feb 12 00:00:00 EST 2021
GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.
Molecular medicine reports
Li SS,Chen DM,Chen LB,Wei H,Wang JL,Xiao J,Huang YH,Lian YF
Tue Jun 01 00:00:00 EDT 2021
ATG5 is instrumental in the transition from autophagy to apoptosis during the degeneration of tick salivary glands.
PLoS neglected tropical diseases
Wang Y,Zhang H,Luo L,Zhou Y,Cao J,Xuan X,Suzuki H,Zhou J
Fri Jan 01 00:00:00 EST 2021
Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling.
Frontiers in cell and developmental biology
Bernatik O,Paclikova P,Kotrbova A,Bryja V,Cajanek L
Tue Mar 16 00:00:00 EDT 2021
One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver.
International journal of molecular sciences
Sugasawa T,Ono S,Yonamine M,Fujita SI,Matsumoto Y,Aoki K,Nakano T,Tamai S,Yoshida Y,Kawakami Y,Takekoshi K
Sat May 29 00:00:00 EDT 2021
Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.
Biochemical and biophysical research communications
Cai Y,Gu WT,Cheng K,Jia PF,Li F,Wang M,Zhang WF,Qiu JT,Wu ZB,Zhao WG
Fri Apr 23 00:00:00 EDT 2021
CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression.
Cancers
Schmitt BM,Boewe AS,Götz C,Philipp SE,Urbschat S,Oertel J,Menger MD,Laschke MW,Ampofo E
Fri Apr 02 00:00:00 EDT 2021
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
The EMBO journal
Xu Y,Shi T,Cui X,Yan L,Wang Q,Xu X,Zhao Q,Xu X,Tang QQ,Tang H,Pan D
Wed Dec 15 00:00:00 EST 2021
Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment.
The Journal of biological chemistry
McKinzey DR,Gomathinayagam S,Griffin WC,Klinzing KN,Jeffries EP,Rajkovic A,Trakselis MA
Tue Aug 24 00:00:00 EDT 2021
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
eLife
Gautheron J,Morisseau C,Chung WK,Zammouri J,Auclair M,Baujat G,Capel E,Moulin C,Wang Y,Yang J,Hammock BD,Cerame B,Phan F,Fève B,Vigouroux C,Andreelli F,Jeru I
Tue Aug 03 00:00:00 EDT 2021
Methylation of dual-specificity phosphatase 4 controls cell differentiation.
Cell reports
Su H,Jiang M,Senevirathne C,Aluri S,Zhang T,Guo H,Xavier-Ferrucio J,Jin S,Tran NT,Liu SM,Sun CW,Zhu Y,Zhao Q,Chen Y,Cable L,Shen Y,Liu J,Qu CK,Han X,Klug CA,Bhatia R,Chen Y,Nimer SD,Zheng YG,Iancu-Rubin C,Jin J,Deng H,Krause DS,Xiang J,Verma A,Luo M,Zhao X
Tue Jul 27 00:00:00 EDT 2021
Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
Cell death & disease
Chang H,Xu Q,Li J,Li M,Zhang Z,Ma H,Yang X
Wed Jul 21 00:00:00 EDT 2021
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Bioorganic chemistry
Liang Y,Zhang M,Zhou P,Liu M,Li J,Wang Y
Fri Oct 01 00:00:00 EDT 2021
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
Journal of immunology (Baltimore, Md. : 1950)
Wen W,Li X,Wang H,Zhao Q,Yin M,Liu W,Chen H,Qian P
Thu Jul 01 00:00:00 EDT 2021
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yan L,Jin W,Zhao Q,Cui X,Shi T,Xu Y,Li F,Jin W,Zhang Z,Zhang Z,Tang QQ,Pan D
Sun Aug 01 00:00:00 EDT 2021
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
Theranostics
Guo S,Meng L,Liu H,Yuan L,Zhao N,Ni J,Zhang Y,Ben J,Li YP,Ma J
Thu Jul 29 00:00:00 EDT 2021
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Frontiers in pharmacology
Tong X,Zhang S,Wang D,Zhang L,Huang J,Zhang T,Fan H
Tue Nov 23 00:00:00 EST 2021
Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.
Journal of virology
Luo MT,Mu D,Yang X,Luo RH,Zheng HY,Chen M,Guo YQ,Zheng YT
Mon Jul 26 00:00:00 EDT 2021
Olanzapine leads to nonalcoholic fatty liver disease through the apolipoprotein A5 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li R,Zhu W,Huang P,Yang Y,Luo F,Dai W,Shen L,Pei W,Huang X
Wed Sep 01 00:00:00 EDT 2021
Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS.
Communications biology
Deng HX,Zhai H,Shi Y,Liu G,Lowry J,Liu B,Ryan ÉB,Yan J,Yang Y,Zhang N,Yang Z,Liu E,Ma YC,Siddique T
Thu Mar 25 00:00:00 EDT 2021
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
eLife
Wang D,Ye Z,Wei W,Yu J,Huang L,Zhang H,Yue J
Fri Nov 19 00:00:00 EST 2021
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Microorganisms
Chen S,Li Y,Chu B,Yuan L,Liu N,Zhu Y,Wang J
Fri Sep 17 00:00:00 EDT 2021
Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90.
JCI insight
Xu G,Fu S,Zhan X,Wang Z,Zhang P,Shi W,Qin N,Chen Y,Wang C,Niu M,Guo Y,Wang J,Bai Z,Xiao X
Mon Jan 25 00:00:00 EST 2021
Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells.
Cell death & disease
Yang WB,Wu AC,Hsu TI,Liou JP,Lo WL,Chang KY,Chen PY,Kikkawa U,Yang ST,Kao TJ,Chen RM,Chang WC,Ko CY,Chuang JY
Tue Sep 28 00:00:00 EDT 2021
Loss of E-cadherin due to road dust PM2.5 activates the EGFR in human pharyngeal epithelial cells.
Environmental science and pollution research international
Tung NT,Ho KF,Niu X,Sun J,Shen Z,Wu F,Cao J,Dung HB,Thuy TPC,Hsiao TC,Liu WT,Chuang HC
Fri Oct 01 00:00:00 EDT 2021
CircSTK40 contributes to recurrent implantation failure via modulating the HSP90/AKT/FOXO1 axis.
Molecular therapy. Nucleic acids
Ni T,Zhang Q,Li Y,Huang C,Zhou T,Yan J,Chen ZJ
Fri Dec 03 00:00:00 EST 2021
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication.
Redox biology
Du L,Xie Y,Zheng K,Wang N,Gao M,Yu T,Cao L,Shao Q,Zou Y,Xia W,Fang Q,Zhao B,Guo D,Peng X,Pan JA
Fri Nov 26 00:00:00 EST 2021
Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.
Journal of agricultural and food chemistry
Zhang Q,Su G,Yang Q,Wei Z,Wang J,Zheng L,Zhao M
Wed Sep 15 00:00:00 EDT 2021
Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150glued.
Molecular brain
Suh BK,Lee SA,Park C,Suh Y,Kim SJ,Woo Y,Nhung TTM,Lee SB,Mun DJ,Goo BS,Choi HS,Kim SJ,Park SK
Mon Jan 18 00:00:00 EST 2021
Metformin inhibits MAPK signaling and rescues pancreatic aquaporin 7 expression to induce insulin secretion in type 2 diabetes mellitus.
The Journal of biological chemistry
He X,Gao F,Hou J,Li T,Tan J,Wang C,Liu X,Wang M,Liu H,Chen Y,Yu Z,Yang M
Sun Aug 01 00:00:00 EDT 2021
Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress.
Cell proliferation
Wu L,He S,Ye W,Shen J,Zhao K,Zhang Y,Zhang R,Wei J,Cao S,Chen K,Le R,Xi C,Kou X,Zhao Y,Wang H,Kang L,Gao S
Mon Nov 01 00:00:00 EDT 2021
Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose-induced senescence and apoptosis.
Experimental and therapeutic medicine
Hong H,Xiao J,Guo Q,Du J,Jiang Z,Lu S,Zhang H,Zhang X,Wang X
Mon Nov 01 00:00:00 EDT 2021
Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.
iScience
Zhang X,Wang Z,Xu Q,Chen Y,Liu W,Zhong T,Li H,Quan C,Zhang L,Cui CP
Fri Oct 22 00:00:00 EDT 2021
Effect of low-intensity motor balance and coordination exercise on cognitive functions, hippocampal Aβ deposition, neuronal loss, neuroinflammation, and oxidative stress in a mouse model of Alzheimer's disease.
Experimental neurology
Nakanishi K,Sakakima H,Norimatsu K,Otsuka S,Takada S,Tani A,Kikuchi K
Mon Mar 01 00:00:00 EST 2021
Identification of fusarielin M as a novel inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB).
Bioorganic chemistry
Chen D,Liu L,Lu Y,Chen S
Fri Jan 01 00:00:00 EST 2021
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells.
Molecules (Basel, Switzerland)
Chen C,Lv Q,Li Y,Jin YH
Sun Jun 27 00:00:00 EDT 2021
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Cell death discovery
Li D,Wang X,Li G,Dang Y,Zhao S,Qin Y
Sun May 16 00:00:00 EDT 2021
MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway.
EBioMedicine
Ling Q,Li F,Zhang X,Mao S,Lin X,Pan J,Ye W,Wei W,Qian Y,Hu C,Huang X,Wang J,Wang H,Huang J,Wang Y,Jin J
Thu Jul 01 00:00:00 EDT 2021
RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic.
International journal of molecular sciences
Ben Saad A,Vauthier V,Lapalus M,Mareux E,Bennana E,Durand-Schneider AM,Bruneau A,Delaunay JL,Gonzales E,Housset C,Aït-Slimane T,Guillonneau F,Jacquemin E,Falguières T
Wed Jun 30 00:00:00 EDT 2021
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Journal of neuroinflammation
Wang M,Feng LR,Li ZL,Ma KG,Chang KW,Chen XL,Yang PB,Ji SF,Ma YB,Han H,Ruganzua JB,Yang WN,Qian YH
Mon Jun 28 00:00:00 EDT 2021
Cholesterol-25-Hydroxylase Suppresses Seneca Valley Virus Infection via Producing 25-Hydroxycholesterol to Block Adsorption Procedure.
Virologica Sinica
Li H,Zhao Z,Li X,Qin L,Wen W,Chen H,Qian P
Fri Oct 01 00:00:00 EDT 2021
p53 induces ARTS to promote mitochondrial apoptosis.
Cell death & disease
Hao Q,Chen J,Liao J,Huang Y,Gan Y,Larisch S,Zeng SX,Lu H,Zhou X
Wed Feb 24 00:00:00 EST 2021
Sirt3 Maintains Microvascular Endothelial Adherens Junction Integrity to Alleviate Sepsis-Induced Lung Inflammation by Modulating the Interaction of VE-Cadherin and β-Catenin.
Oxidative medicine and cellular longevity
Chen DQ,Shen MJ,Wang H,Li Y,Tang AL,Li S,Xiong MC,Guo Y,Zhang GQ
Fri Feb 04 00:00:00 EST 2022
Identification of the Bcl-2 and Bax homologs from Rhipicephalus haemaphysaloides and their function in the degeneration of tick salivary glands.
Parasites & vectors
Hu S,Wang Y,Xu Z,Zhou Y,Cao J,Zhang H,Zhou J
Wed Aug 04 00:00:00 EDT 2021
Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3.
Immunology
Chen X,Xu Y,Tu W,Huang F,Zuo Y,Zhang HG,Jin L,Feng Q,Ren T,He J,Miao Y,Yuan Y,Zhao Q,Liu J,Zhang R,Zhu L,Qian F,Zhu C,Zheng H,Wang J
Thu Jul 01 00:00:00 EDT 2021
Effects of detraining on preconditioning exercise-induced neuroprotective potential after ischemic stroke in rats.
Brain structure & function
Otsuka S,Sakakima H,Tani A,Nakanishi K,Takada S,Norimatsu K,Maejima H,Maruyama I
Wed Sep 01 00:00:00 EDT 2021
Pinocembrin relieves lipopolysaccharide and bleomycin induced lung inflammation via inhibiting TLR4-NF-κB-NLRP3 inflammasome signaling pathway.
International immunopharmacology
Gan W,Li X,Cui Y,Xiao T,Liu R,Wang M,Wei Y,Cui M,Ren S,Helian K,Ning W,Zhou H,Yang C
Fri Jan 01 00:00:00 EST 2021
HOIL-1-catalysed, ester-linked ubiquitylation restricts IL-18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages.
The FEBS journal
Petrova T,Zhang J,Nanda SK,Figueras-Vadillo C,Cohen P
Fri Oct 01 00:00:00 EDT 2021
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Cell death discovery
Ge W,Wang Y,Zheng S,Zhao D,Wang X,Zhang X,Hu Y
Mon Jul 26 00:00:00 EDT 2021
Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis.
Theranostics
Zheng Q,Li P,Zhou X,Qiang Y,Fan J,Lin Y,Chen Y,Guo J,Wang F,Xue H,Xiong J,Li F
Fri Feb 04 00:00:00 EST 2022
Ginsenoside Rb1 protected PC12 cells from Aβ25-35-induced cytotoxicity via PPARγ activation and cholesterol reduction.
European journal of pharmacology
Changhong K,Peng Y,Yuan Z,Cai J
Mon Feb 15 00:00:00 EST 2021
Nuclear Lamin A/C Expression Is a Key Determinant of Paclitaxel Sensitivity.
Molecular and cellular biology
Smith ER,Leal J,Amaya C,Li B,Xu XX
Wed Jun 23 00:00:00 EDT 2021
Androgen-dependent and DNA-binding-independent association of androgen receptor with chromatic regions coding androgen-induced noncoding RNAs.
Bioscience, biotechnology, and biochemistry
Sawada T,Nishimura K,Mori J,Kanemoto Y,Kouzmenko A,Amano R,Hayakawa A,Tokiwa S,Shimmura H,Kato S
Wed Sep 22 00:00:00 EDT 2021
Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.
International journal of molecular sciences
Zhou H,Su H,Chen W
Wed Sep 01 00:00:00 EDT 2021
RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense.
Cell death and differentiation
Guo X,Ma P,Li Y,Yang Y,Wang C,Xu T,Wang H,Li C,Mao B,Qi X
Mon Feb 01 00:00:00 EST 2021
Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors.
PloS one
Anchoori RK,George L,Tseng SH,Lam B,Polkampally S,Amiano AD,Foran P,Tsingine H,Samanapally H,Carrizo Velasquez F,Das S,Xing D,Bin Salam A,Karanam B,Hung CF,Roden RBS
Thu Nov 18 00:00:00 EST 2021
Comprehensive Analysis of the Expression and Prognosis Value of Chromobox Family Members in Clear Cell Renal Cell Carcinoma.
Frontiers in oncology
Zhu Y,Pu Z,Li Z,Lin Y,Li N,Peng F
Tue Aug 17 00:00:00 EDT 2021
Triple-Negative Breast Cancer Cells Recruit Neutrophils by Secreting TGF-β and CXCR2 Ligands.
Frontiers in immunology
SenGupta S,Hein LE,Xu Y,Zhang J,Konwerski JR,Li Y,Johnson C,Cai D,Smith JL,Parent CA
Mon Oct 18 00:00:00 EDT 2021
Cadmium exposure induces osteoporosis through cellular senescence, associated with activation of NF-κB pathway and mitochondrial dysfunction.
Environmental pollution (Barking, Essex : 1987)
Luo H,Gu R,Ouyang H,Wang L,Shi S,Ji Y,Bao B,Liao G,Xu B
Wed Dec 01 00:00:00 EST 2021
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
Molecular immunology
Li M,Lu H,Wang X,Duan C,Zhu X,Zhang Y,Ge X,Ji F,Wang X,Su J,Zhang D
Wed Dec 01 00:00:00 EST 2021
Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway.
Journal of immunology research
Lin Y,Xie Y,Hao Z,Bi H,Liu Y,Yang X,Xia Y
Thu Mar 03 00:00:00 EST 2022
CUL4high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival.
The American journal of pathology
Wang Y,Yan F,Nasar A,Chen ZS,Altorki NK,Stiles B,Narula N,Zhou P
Wed Sep 01 00:00:00 EDT 2021
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Frontiers in pharmacology
Han Y,Jiang M,He R,Lv X,Liao X,He Y,Zhang F,Long L,Jiang G,Peng Z,Tao L,Hu G,Meng J
Tue Oct 12 00:00:00 EDT 2021
Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway.
Frontiers in veterinary science
Lin Z,Lin Z,Zhao Y,Cheng N,Zhang D,Lin J,Zhang H,Lin D
Tue Jan 04 00:00:00 EST 2022
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Research in veterinary science
Xing Y,Wang L,Xu G,Guo S,Zhang M,Cheng G,Liu Y,Liu J
Mon Nov 01 00:00:00 EDT 2021
Caspase-3/NLRP3 signaling in the mesenchymal stromal niche regulates myeloid-biased hematopoiesis.
Stem cell research & therapy
Zhang J,Chen Y,Yin D,Feng F,An Q,Liu Z,An N,Xu J,Yi J,Gu S,Yin W,Wang Y,Hu X
Sat Nov 20 00:00:00 EST 2021
Gut Metabolite Trimethylamine N-Oxide Protects INS-1 β-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions.
Biomolecules
Krueger ES,Beales JL,Russon KB,Elison WS,Davis JR,Hansen JM,Neilson AP,Hansen JM,Tessem JS
Fri Dec 17 00:00:00 EST 2021
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Life science alliance
Ibe NU,Subramanian A,Mukherjee S
Wed Dec 01 00:00:00 EST 2021
PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling.
Frontiers in molecular biosciences
Guo XW,Zhang H,Huang JQ,Wang SN,Lu Y,Cheng B,Dong SH,Wang YY,Li FS,Li YW
Wed Sep 29 00:00:00 EDT 2021
Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.
Biochemical pharmacology
Wu H,Chen Y,Li B,Li C,Guo J,You J,Hu X,Kuang D,Qi S,Liu P,Li L,Xu C
Mon Feb 01 00:00:00 EST 2021
Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC).
OncoTargets and therapy
Huang GZ,Wu QQ,Zheng ZN,Shao TR,Li F,Lu XY,Ye HY,Chen GX,Song YX,Zeng WS,Ai YL,Lv XZ
Thu Apr 21 00:00:00 EDT 2022
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia.
Science advances
Srivastava S,Sahu U,Zhou Y,Hogan AK,Sathyan KM,Bodner J,Huang J,Wong KA,Khalatyan N,Savas JN,Ntziachristos P,Ben-Sahra I,Foltz DR
Fri Jan 01 00:00:00 EST 2021
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hao W,Hao C,Wu C,Xu Y,Wu S,Lu X,Yang J,Jin C
Mon Nov 01 00:00:00 EDT 2021
Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway.
Frontiers in pharmacology
Lv X,Yao T,He R,He Y,Li M,Han Y,Zhang Y,Long L,Jiang G,Cheng X,Xie Y,Huang L,Peng Z,Hu G,Li Q,Tao L,Meng J
Fri Jan 07 00:00:00 EST 2022
Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants.
Liver international : official journal of the International Association for the Study of the Liver
Ben Saad A,Vauthier V,Tóth Á,Janaszkiewicz A,Durand-Schneider AM,Bruneau A,Delaunay JL,Lapalus M,Mareux E,Garcin I,Gonzales E,Housset C,Aït-Slimane T,Jacquemin E,Di Meo F,Falguières T
Tue Jun 01 00:00:00 EDT 2021
Enterovirus D68 Protease 2Apro Targets TRAF3 To Subvert Host Innate Immune Responses.
Journal of virology
Kang J,Pang Z,Zhou Z,Li X,Liu S,Cheng J,Liu P,Tan W,Wang Z,Wang T
Wed Jan 13 00:00:00 EST 2021
Small Molecule Palmatine Targeting Musashi-2 in Colorectal Cancer.
Frontiers in pharmacology
Zhang X,Su K,Liu Y,Zhu D,Pan Y,Ke X,Qu Y
Wed Feb 16 00:00:00 EST 2022
Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer.
FEBS open bio
Yang Z,Sun H,Ma W,Wu K,Peng G,Ou T,Wu S
Wed Sep 01 00:00:00 EDT 2021
Melatonin Alleviates Renal Injury in Mouse Model of Sepsis.
Frontiers in pharmacology
Chen L,Han Z,Shi Z,Liu C,Lu Q
Tue Sep 21 00:00:00 EDT 2021
Screening and identification of autophagy-related biomarkers for oral squamous cell carcinoma (OSCC) via integrated bioinformatics analysis.
Journal of cellular and molecular medicine
Huang GZ,Lu ZY,Rao Y,Gao H,Lv XZ
Sat May 01 00:00:00 EDT 2021
CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes.
Pharmacological research
Yang Y,Li J,Zhang L,Lin Z,Xiao H,Sun X,Zhang M,Liu P,Huang H
Fri Jan 01 00:00:00 EST 2021
Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
iScience
Zou Q,Yang L,Shi R,Qi Y,Zhang X,Qi H
Fri Dec 17 00:00:00 EST 2021
Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK1.
Molecular therapy. Nucleic acids
Zhu M,Liang Z,Pan J,Zhang X,Xue R,Cao G,Hu X,Gong C
Fri Sep 03 00:00:00 EDT 2021
Nitrogen-Doped Multiwalled Carbon Nanotubes Enhance Bone Remodeling through Immunomodulatory Functions.
ACS applied materials & interfaces
Li H,He D,Xiao X,Yu G,Hu G,Zhang W,Wen X,Lin Y,Li X,Lin H,Diao Y,Tang Y
Wed Jun 02 00:00:00 EDT 2021
BRCC36 functions noncatalytically to promote antiviral response by maintaining STAT1 protein stability.
European journal of immunology
Cheng Q,Feng Q,Xu Y,Zuo Y,Liu J,Yuan Y,Miao Y,Liu Y,Lei L,Guo T,Zhang L,Wu D,Zheng H
Mon Feb 01 00:00:00 EST 2021
BCL7C suppresses ovarian cancer growth by inactivating mutant p53.
Journal of molecular cell biology
Huang C,Hao Q,Shi G,Zhou X,Zhang Y
Fri May 07 00:00:00 EDT 2021
ORMDL1 is upregulated and associated with favorable outcomes in colorectal cancer.
Translational oncology
Wang Q,Liu W,Chen S,Luo Q,Li Y,Peng S,Wang H,Liu X,Chen D
Fri Oct 01 00:00:00 EDT 2021
Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.
Frontiers in cardiovascular medicine
Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y
Tue Jan 11 00:00:00 EST 2022
Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.
Frontiers in cardiovascular medicine
Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y
Tue Jan 11 00:00:00 EST 2022
Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.
Frontiers in cardiovascular medicine
Cui L,Zhang Q,Huang Y,Yang L,Zhang J,Jiang X,Jia J,Lv Y,Zhang D,Huang Y
Tue Jan 11 00:00:00 EST 2022
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.
Nature communications
Shangguan X,He J,Ma Z,Zhang W,Ji Y,Shen K,Yue Z,Li W,Xin Z,Zheng Q,Cao Y,Pan J,Dong B,Cheng J,Wang Q,Xue W
Mon Mar 22 00:00:00 EDT 2021
Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy.
ACS nano
Xie S,Sun W,Zhang C,Dong B,Yang J,Hou M,Xiong L,Cai B,Liu X,Xue W
Tue Apr 27 00:00:00 EDT 2021
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.
Molecular therapy. Nucleic acids
Li D,Wang X,Dang Y,Zhang X,Zhao S,Lu G,Chan WY,Leung PCK,Qin Y
Fri Mar 05 00:00:00 EST 2021
Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer.
Frontiers in oncology
Lin Z,Li Q,Zhao Y,Lin Z,Cheng N,Zhang D,Liu G,Lin J,Zhang H,Lin D
Wed Dec 15 00:00:00 EST 2021
Regulation of PDGFR-β gene expression by targeting the G-vacancy bearing G-quadruplex in promoter.
Nucleic acids research
Chen JN,He YD,Liang HT,Cai TT,Chen Q,Zheng KW
Thu Dec 16 00:00:00 EST 2021
A newly identified small molecular compound acts as a protein kinase inhibitor to suppress metastasis of colorectal cancer.
Bioorganic chemistry
Qi L,Zhang Y,Song F,Han Y,Ding Y
Mon Feb 01 00:00:00 EST 2021
SIRT2 ablation inhibits glucose-stimulated insulin secretion through decreasing glycolytic flux.
Theranostics
Zhou F,Zhang L,Zhu K,Bai M,Zhang Y,Zhu Q,Wang S,Sheng C,Yuan M,Liu Y,Lu J,Shao L,Wang X,Zhou L
Mon Aug 16 00:00:00 EDT 2021
TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Cell death and differentiation
Nie X,Xiao D,Ge Y,Xie Y,Zhou H,Zheng T,Li X,Liu H,Huang H,Zhao Y
Mon Mar 01 00:00:00 EST 2021
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model.
Journal of neuroinflammation
Liu T,Li T,Chen X,Li Z,Feng M,Yao W,Wan L,Zhang C,Zhang Y
Thu Sep 16 00:00:00 EDT 2021
Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells.
BMC cancer
Amaya C,Luo S,Baigorri J,Baucells R,Smith ER,Xu XX
Wed Sep 01 00:00:00 EDT 2021
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Immunity
Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H
Tue Jul 14 00:00:00 EDT 2020
Targeting PML in triple negative breast cancer elicits growth suppression and senescence.
Cell death and differentiation
Arreal L,Piva M,Fernández S,Revandkar A,Schaub-Clerigué A,Villanueva J,Zabala-Letona A,Pujana M,Astobiza I,Cortazar AR,Hermanova I,Bozal-Basterra L,Arruabarrena-Aristorena A,Crespo JR,Valcarcel-Jimenez L,Zúñiga-García P,Canals F,Torrano V,Barrio R,Sutherland JD,Alimonti A,Martin-Martin N,Carracedo A
Wed Apr 01 00:00:00 EDT 2020
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
PLoS pathogens
Liu J,Jin L,Chen X,Yuan Y,Zuo Y,Miao Y,Feng Q,Zhang H,Huang F,Guo T,Zhang L,Zhu L,Qian F,Zhu C,Zheng H
Wed Jan 01 00:00:00 EST 2020
SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells.
Molecular oncology
Dou J,Zhang H,Chen R,Shu Z,Yuan H,Zhao X,Wang Y,Huang J,Zhou A,Yu J
Tue Sep 01 00:00:00 EDT 2020
Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress.
Oncogenesis
Zhang J,Duan H,Feng Z,Han X,Gu C
Tue May 12 00:00:00 EDT 2020
FNDC3B 3'-UTR shortening escapes from microRNA-mediated gene repression and promotes nasopharyngeal carcinoma progression.
Cancer science
Li YQ,Chen Y,Xu YF,He QM,Yang XJ,Li YQ,Hong XH,Huang SY,Tang LL,Liu N
Mon Jun 01 00:00:00 EDT 2020
Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape.
Journal of immunology (Baltimore, Md. : 1950)
Li Z,Wang J,Zhang X,Liu P,Zhang X,Wang J,Zheng X,Wei L,Peng Q,Liu C,Yan Q,Shen S,Li X,Ma J
Fri May 01 00:00:00 EDT 2020
Prohibitin (PHB) interacts with AKT in mitochondria to coordinately modulate sperm motility.
Asian journal of andrology
Li XH,Chai RR,Chen GW,Zhang LF,Tan-Tai WJ,Shi HJ,Martin-DeLeon PA,O WS,Chen H
Wed Sep 22 00:00:00 EDT 2021
Circular RNA CRIM1 functions as a ceRNA to promote nasopharyngeal carcinoma metastasis and docetaxel chemoresistance through upregulating FOXQ1.
Molecular cancer
Hong X,Liu N,Liang Y,He Q,Yang X,Lei Y,Zhang P,Zhao Y,He S,Wang Y,Li J,Li Q,Ma J,Li Y
Sat Feb 15 00:00:00 EST 2020
Effects of peptidoglycan on the development of steatohepatitis.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Jin M,Lai Y,Zhao P,Shen Q,Su W,Yin Y,Zhang W
Wed Apr 01 00:00:00 EDT 2020
Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.
EMBO molecular medicine
Li SB,Liu YY,Yuan L,Ji MF,Zhang A,Li HY,Tang LQ,Fang SG,Zhang H,Xing S,Li MZ,Zhong Q,Lin SJ,Liu WL,Huang P,Zeng YX,Zheng YM,Ling ZQ,Sui JH,Zeng MS
Mon Sep 07 00:00:00 EDT 2020
Murine Cytomegalovirus Protein pM49 Interacts with pM95 and Is Critical for Viral Late Gene Expression.
Journal of virology
Han T,Hao H,Sleman SS,Xuan B,Tang S,Yue N,Qian Z
Fri Feb 28 00:00:00 EST 2020
Generation and Application of Mouse Monoclonal Antibody Against Human Cytomegalovirus UL23.
Viral immunology
Li W,Chai H,Feng L,Deng J,Yang X,Ran Y,Li H
Mon Jun 01 00:00:00 EDT 2020
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation.
Science advances
Guerra J,Valadao AL,Vlachakis D,Polak K,Vila IK,Taffoni C,Prabakaran T,Marriott AS,Kaczmarek R,Houel A,Auzemery B,Déjardin S,Boudinot P,Nawrot B,Jones NJ,Paludan SR,Kossida S,Langevin C,Laguette N
Fri May 01 00:00:00 EDT 2020
Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction.
Frontiers in immunology
Wen W,Zhao Q,Yin M,Qin L,Hu J,Chen H,Li X,Qian P
Tue Jun 15 00:00:00 EDT 2021
ChREBP-β regulates thermogenesis in brown adipose tissue.
The Journal of endocrinology
Wei C,Ma X,Su K,Qi S,Zhu Y,Lin J,Wang C,Yang R,Chen X,Wang W,Zhang WJ
Mon Jun 01 00:00:00 EDT 2020
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
Molecular biomedicine
Zhou J,Tan Y,Zhang Y,Tong A,Shen X,Sun X,Jia D,Sun Q
Wed Dec 30 00:00:00 EST 2020
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling.
Development (Cambridge, England)
Ma P,An T,Zhu L,Zhang L,Wang H,Ren B,Sun B,Zhou X,Li Y,Mao B
Mon Jun 15 00:00:00 EDT 2020
LncRNA UCA1 maintains the low-tumorigenic and nonmetastatic status by stabilizing E-cadherin in primary prostate cancer cells.
Molecular carcinogenesis
Zhao X,Wang Y,He J,Deng R,Huang X,Guo Y,Li L,Xie R,Yu J
Thu Oct 01 00:00:00 EDT 2020
Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1.
Frontiers in microbiology
Zhang HG,Guo J,Yuan Y,Zuo Y,Liu J,Zhu L,Miao Y,Chen X,Jin L,Huang F,Ren T,He J,Shi W,Wen Z,Zhu C,Zheng H,Dong C,Qian F
Fri Dec 18 00:00:00 EST 2020
Downregulation of miR-146b-5p via iodine involvement repressed papillary thyroid carcinoma cell proliferation.
Journal of molecular endocrinology
Pan Y,Yun W,Shi B,Cui R,Liu C,Ding Z,Fan J,Jiang W,Tang J,Zheng T,Yu X,Liu Y
Sat Aug 01 00:00:00 EDT 2020
DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway.
Scientific reports
Fujii A,Sunatani Y,Furuichi K,Fujimoto K,Adachi H,Iwabuchi K,Yokoyama H
Thu Dec 17 00:00:00 EST 2020
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
American journal of physiology. Renal physiology
Ye C,Xiong W,Lei CT,Tang H,Su H,Yi F,Zhang C
Thu Oct 01 00:00:00 EDT 2020
Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner.
Biomaterials
Huang L,Yan W,Cai B,Song Y,Lv Q,Wang G,Wang L,Wang Z
Sat Aug 01 00:00:00 EDT 2020
RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
Cell death and differentiation
Zheng T,Zhou H,Li X,Peng D,Yang Y,Zeng Y,Liu H,Ren J,Zhao Y
Sun Nov 01 00:00:00 EDT 2020
ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo.
Experimental and therapeutic medicine
Li M,Fan Y,Wang Y,Xu J,Xu H
Sat Aug 01 00:00:00 EDT 2020
Flavin adenine dinucleotide ameliorates hypertensive vascular remodeling via activating short chain acyl-CoA dehydrogenase.
Life sciences
Zhong X,Ma Z,Su Y,Li Z,Liao Y,Pan X,Zang L,Zhou S
Thu Oct 01 00:00:00 EDT 2020
Maintaining protein stability of ΔNp63 via USP28 is required by squamous cancer cells.
EMBO molecular medicine
Prieto-Garcia C,Hartmann O,Reissland M,Braun F,Fischer T,Walz S,Schülein-Völk C,Eilers U,Ade CP,Calzado MA,Orian A,Maric HM,Münch C,Rosenfeldt M,Eilers M,Diefenbacher ME
Tue Apr 07 00:00:00 EDT 2020
Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Lin T,Luo W,Li Z,Zhang L,Zheng X,Mai L,Yang W,Guan G,Su Z,Liu P,Li Z,Xie Y
Tue Dec 01 00:00:00 EST 2020
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Nature communications
Zuo Y,Feng Q,Jin L,Huang F,Miao Y,Liu J,Xu Y,Chen X,Zhang H,Guo T,Yuan Y,Zhang L,Wang J,Zheng H
Mon Mar 02 00:00:00 EST 2020
METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.
Molecular cell
Zhang C,Chen L,Peng D,Jiang A,He Y,Zeng Y,Xie C,Zhou H,Luo X,Liu H,Chen L,Ren J,Wang W,Zhao Y
Thu Aug 06 00:00:00 EDT 2020
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Aging
Huang GZ,Wu QQ,Zheng ZN,Shao TR,Chen YC,Zeng WS,Lv XZ
Thu Jun 11 00:00:00 EDT 2020
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Cell death & disease
Liu H,Xie S,Fang F,Kalvakolanu DV,Xiao W
Wed Jun 10 00:00:00 EDT 2020
Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.
Molecular cancer research : MCR
Koppenhafer SL,Goss KL,Terry WW,Gordon DJ
Wed Jan 01 00:00:00 EST 2020
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Journal of experimental & clinical cancer research : CR
Sun Z,Zhang Q,Yuan W,Li X,Chen C,Guo Y,Shao B,Dang Q,Zhou Q,Wang Q,Wang G,Liu J,Kan Q
Fri Nov 20 00:00:00 EST 2020
Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.
Cell reports
Li S,Wu Z,Li Y,Tantray I,De Stefani D,Mattarei A,Krishnan G,Gao FB,Vogel H,Lu B
Tue Aug 04 00:00:00 EDT 2020
lncMGPF is a novel positive regulator of muscle growth and regeneration.
Journal of cachexia, sarcopenia and muscle
Lv W,Jin J,Xu Z,Luo H,Guo Y,Wang X,Wang S,Zhang J,Zuo H,Bai W,Peng Y,Tang J,Zhao S,Zuo B
Tue Dec 01 00:00:00 EST 2020
A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia.
Oncogene
Wang X,Wang Y,Li L,Xue X,Xie H,Shi H,Hu Y
Sat Feb 01 00:00:00 EST 2020
ITM2A as a Tumor Suppressor and Its Correlation With PD-L1 in Breast Cancer.
Frontiers in oncology
Zhang R,Xu T,Xia Y,Wang Z,Li X,Chen W
Thu Apr 21 00:00:00 EDT 2022
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Journal of extracellular vesicles
Jiang W,Ma P,Deng L,Liu Z,Wang X,Liu X,Long G
Sat Oct 24 00:00:00 EDT 2020
A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
Fitoterapia
Liu DM,Cao ZX,Yan HL,Li W,Yang F,Zhao WJ,Diao QC,Tan YZ
Sun Mar 01 00:00:00 EST 2020
Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact.
Cell death and differentiation
Tang J,Zhang K,Dong J,Yan C,Hu C,Ji H,Chen L,Chen S,Zhao H,Song Z
Wed Jan 01 00:00:00 EST 2020
Initiator and executioner caspases in salivary gland apoptosis of Rhipicephalus haemaphysaloides.
Parasites & vectors
Wang Y,Hu S,Tuerdi M,Yu X,Zhang H,Zhou Y,Cao J,da Silva Vaz I,Zhou J
Fri Jun 05 00:00:00 EDT 2020
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Clinical science (London, England : 1979)
Sun X,Huang K,Haiming X,Lin Z,Yang Y,Zhang M,Liu P,Huang H
Fri Jul 17 00:00:00 EDT 2020
Small-molecule inhibitors of ubiquitin-specific protease 7 enhance type-I interferon antiviral efficacy by destabilizing SOCS1.
Immunology
Yuan Y,Miao Y,Zeng C,Liu J,Chen X,Qian L,Wang X,Qian F,Yu Z,Wang J,Qian G,Fu Q,Lv H,Zheng H
Sun Mar 01 00:00:00 EST 2020
NAF-1 Inhibition by Resveratrol Suppresses Cancer Stem Cell-Like Properties and the Invasion of Pancreatic Cancer.
Frontiers in oncology
Qin T,Cheng L,Xiao Y,Qian W,Li J,Wu Z,Wang Z,Xu Q,Duan W,Wong L,Wu E,Ma Q,Ma J
Mon Sep 28 00:00:00 EDT 2020
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency.
Journal of cellular physiology
Zhang X,Dang Y,Liu R,Zhao S,Ma J,Qin Y
Sun Nov 01 00:00:00 EDT 2020
GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.
Biochemical and biophysical research communications
Guo S,Ouyang S,Wang X,Liao A,Yuan S
Thu Aug 27 00:00:00 EDT 2020
Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
Cell reports
Yomtoubian S,Lee SB,Verma A,Izzo F,Markowitz G,Choi H,Cerchietti L,Vahdat L,Brown KA,Andreopoulou E,Elemento O,Chang J,Inghirami G,Gao D,Ryu S,Mittal V
Tue Jan 21 00:00:00 EST 2020
A role of cellular translation regulation associated with toxic Huntingtin protein.
Cellular and molecular life sciences : CMLS
Joag H,Ghatpande V,Desai M,Sarkar M,Raina A,Shinde M,Chitale R,Deo A,Bose T,Majumdar A
Tue Sep 01 00:00:00 EDT 2020
Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion.
Science signaling
Lee S,Park H,Zhu PP,Jung SY,Blackstone C,Chang J
Tue Jan 07 00:00:00 EST 2020
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Cell death & disease
Zhang Y,Zhao S,Fu Y,Yan L,Feng Y,Chen Y,Wu Y,Deng Y,Zhang G,Chen Z,Chen Y,Liu T
Tue Aug 18 00:00:00 EDT 2020
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules.
Biochimica et biophysica acta. Molecular cell research
Tang K,Li S,Li P,Xia Q,Yang R,Li T,Li L,Jiang Y,Qin X,Yang H,Wu C,You F,Tan Y,Liu Y
Fri May 01 00:00:00 EDT 2020
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
Acta neuropathologica communications
Tsai MH,Cheng HY,Nian FS,Liu C,Chao NH,Chiang KL,Chen SF,Tsai JW
Tue Jul 14 00:00:00 EDT 2020
Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway.
Biomaterials
Ni R,Song G,Fu X,Song R,Li L,Pu W,Gao J,Hu J,Liu Q,He F,Zhang D,Huang G
Sat Feb 01 00:00:00 EST 2020
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Frontiers in immunology
Geng N,Wang X,Yu X,Wang R,Zhu Y,Zhang M,Liu J,Liu Y
Mon Mar 29 00:00:00 EDT 2021
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Frontiers in immunology
Geng N,Wang X,Yu X,Wang R,Zhu Y,Zhang M,Liu J,Liu Y
Mon Mar 29 00:00:00 EDT 2021
Melatonin protects mouse testes from palmitic acid-induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1-dependent manner.
Journal of pineal research
Xu D,Liu L,Zhao Y,Yang L,Cheng J,Hua R,Zhang Z,Li Q
Sun Nov 01 00:00:00 EDT 2020
Structural basis for DEAH-helicase activation by G-patch proteins.
Proceedings of the National Academy of Sciences of the United States of America
Studer MK,Ivanović L,Weber ME,Marti S,Jonas S
Tue Mar 31 00:00:00 EDT 2020
HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation.
Cell stress
Zhao JF,Rodger CE,Allen GFG,Weidlich S,Ganley IG
Wed Mar 04 00:00:00 EST 2020
CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.
Journal of hematology & oncology
Domínguez JM,Pérez-Chacón G,Guillén MJ,Muñoz-Alonso MJ,Somovilla-Crespo B,Cibrián D,Acosta-Iborra B,Adrados M,Muñoz-Calleja C,Cuevas C,Sánchez-Madrid F,Avilés P,Zapata JM
Tue Apr 07 00:00:00 EDT 2020
Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha.
Pharmacology
Yu X,Wang S,Wang J,Gong J,Shi J,Yu S
Wed Feb 03 00:00:00 EST 2021
High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy.
Molecular brain
Su P,Ying M,Han Z,Xia J,Jin S,Li Y,Wang H,Xu F
Mon Jan 13 00:00:00 EST 2020
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Su H,Ye C,Lei CT,Tang H,Zeng JY,Yi F,Zhang C
Wed Jan 01 00:00:00 EST 2020
Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma.
Cancer research
Slemmons KK,Yeung C,Baumgart JT,Juarez JOM,McCalla A,Helman LJ
Wed Jul 15 00:00:00 EDT 2020
β-Actin facilitates etoposide-induced p53 nuclear import.
Journal of biosciences
Qi W,Li J,Pei X,Ke Y,Bu Q,Ni X
Fri Nov 13 00:00:00 EST 2020
The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress.
Autophagy
Shim MS,Nettesheim A,Hirt J,Liton PB
Wed Jul 01 00:00:00 EDT 2020
The protective effect of rosmarinic acid on myotube formation during myoblast differentiation under heat stress.
In vitro cellular & developmental biology. Animal
Chen KL,Wang Y,Lin ZP,Li HX
Tue Sep 01 00:00:00 EDT 2020
Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis.
Disease models & mechanisms
Aoudjehane L,Gautheron J,Le Goff W,Goumard C,Gilaizeau J,Nget CS,Savier E,Atif M,Lesnik P,Morichon R,Chrétien Y,Calmus Y,Scatton O,Housset C,Conti F
Wed Apr 29 00:00:00 EDT 2020
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Molecular cell
Yuan Y,Miao Y,Qian L,Zhang Y,Liu C,Liu J,Zuo Y,Feng Q,Guo T,Zhang L,Chen X,Jin L,Huang F,Zhang H,Zhang W,Li W,Xu G,Zheng H
Thu Feb 20 00:00:00 EST 2020
A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation.
Nucleic acids research
Maltby CJ,Schofield JPR,Houghton SD,O'Kelly I,Vargas-Caballero M,Deinhardt K,Coldwell MJ
Fri Sep 25 00:00:00 EDT 2020
Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Cancers
Ke C,Hou H,Li J,Su K,Huang C,Lin Y,Lu Z,Du Z,Tan W,Yuan Z
Mon May 04 00:00:00 EDT 2020
USP39 Serves as a Deubiquitinase to Stabilize STAT1 and Sustains Type I IFN-Induced Antiviral Immunity.
Journal of immunology (Baltimore, Md. : 1950)
Peng Y,Guo J,Sun T,Fu Y,Zheng H,Dong C,Xiong S
Tue Dec 01 00:00:00 EST 2020
Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo.
Medical science monitor : international medical journal of experimental and clinical research
Sun Y,Pan H,Shen S,Xia Z,Yu Z,Li C,Sun P,Xin C
Thu Jul 16 00:00:00 EDT 2020
Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity.
Life science alliance
Zachari M,Longo M,Ganley IG
Tue Dec 01 00:00:00 EST 2020
Precise and efficient silencing of mutant KrasG12D by CRISPR-CasRx controls pancreatic cancer progression.
Theranostics
Jiang W,Li H,Liu X,Zhang J,Zhang W,Li T,Liu L,Yu X
Tue Jun 01 00:00:00 EDT 2021
Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells.
British journal of cancer
Teratake Y,Takashina T,Iijima K,Sakuma T,Yamamoto T,Ishizaka Y
Sun Mar 01 00:00:00 EST 2020
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Frontiers in cell and developmental biology
Zhang T,Li H,Wang K,Xu B,Chen ZN,Bian H
Mon Sep 28 00:00:00 EDT 2020
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Carcinogenesis
Tang H,Chu Y,Huang Z,Cai J,Wang Z
Wed Apr 22 00:00:00 EDT 2020
FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Park SY,Koh HC
Sun Mar 01 00:00:00 EST 2020
Circular RNA circ_0026359 Enhances Cisplatin Resistance in Gastric Cancer via Targeting miR-1200/POLD4 Pathway.
BioMed research international
Zhang Z,Yu X,Zhou B,Zhang J,Chang J
Wed May 05 00:00:00 EDT 2021
A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.
International journal of molecular medicine
Fan J,Ji CC,Cheng YJ,Yao H,Chen XM,Zheng ZH,Wu SH
Sun Mar 01 00:00:00 EST 2020
Oxytocin Alleviates MPTP-Induced Neurotoxicity in Mice by Targeting MicroRNA-26a/Death-Associated Protein Kinase 1 Pathway.
Journal of Alzheimer's disease : JAD
Almansoub HAMM,Tang H,Wu Y,Wang DQ,Mahaman YAR,Salissou MTM,Lu Y,Hu F,Zhou LT,Almansob YAM,Liu D
Mon Apr 19 00:00:00 EDT 2021
Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos.
Nature communications
Chen M,Zhu Q,Li C,Kou X,Zhao Y,Li Y,Xu R,Yang L,Yang L,Gu L,Wang H,Liu X,Jiang C,Gao S
Tue Apr 14 00:00:00 EDT 2020
Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.
Biochemical and biophysical research communications
Miyauchi Y,Kurita A,Yamashita R,Takamatsu T,Ikushiro S,Mackenzie PI,Tanaka Y,Ishii Y
Thu Apr 30 00:00:00 EDT 2020
Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.
International immunopharmacology
Qian G,Zhu L,Huang C,Liu Y,Ren Y,Ding Y,Qian W,Xu Q,Zheng H,Lv H
Thu Oct 01 00:00:00 EDT 2020
Nuclear import of NLS- RARα is mediated by importin α/β.
Cellular signalling
Ye J,Zhong L,Xiong L,Li J,Yu L,Dan W,Yuan Z,Yao J,Zhong P,Liu J,Liu D,Liu B
Fri May 01 00:00:00 EDT 2020
PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval.
Cell reports
Yong XLH,Cousin MA,Anggono V
Tue Oct 27 00:00:00 EDT 2020
WD40 repeat and FYVE domain containing 3 is essential for cardiac development.
Cardiovascular research
Zhang S,Song Z,An L,Liu X,Hu XW,Naz A,Zhou R,Guo X,He L,Zhu H
Mon Jul 01 00:00:00 EDT 2019
WD40 repeat and FYVE domain containing 3 is essential for cardiac development.
Cardiovascular research
Zhang S,Song Z,An L,Liu X,Hu XW,Naz A,Zhou R,Guo X,He L,Zhu H
Mon Jul 01 00:00:00 EDT 2019
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Oncogene
Zhang H,Wang Y,Dou J,Guo Y,He J,Li L,Liu X,Chen R,Deng R,Huang J,Xie R,Zhao X,Yu J
Fri Feb 01 00:00:00 EST 2019
Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis.
Oncogene
Zhang H,Wang Y,Dou J,Guo Y,He J,Li L,Liu X,Chen R,Deng R,Huang J,Xie R,Zhao X,Yu J
Fri Feb 01 00:00:00 EST 2019
The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma.
Frontiers in oncology
Cheng F,Zhang P,Xiao Q,Li Y,Dong M,Wang H,Kuang D,He Y,Duan Q,Mao F,Wang B,Guo D
Sat Nov 04 00:00:00 EDT 2023
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
American journal of physiology. Cell physiology
Kang H,Hong Z,Zhong M,Klomp J,Bayless KJ,Mehta D,Karginov AV,Hu G,Malik AB
Tue Jan 01 00:00:00 EST 2019
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.
American journal of physiology. Cell physiology
Kang H,Hong Z,Zhong M,Klomp J,Bayless KJ,Mehta D,Karginov AV,Hu G,Malik AB
Tue Jan 01 00:00:00 EST 2019
Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.
Brain structure & function
Otsuka S,Sakakima H,Terashi T,Takada S,Nakanishi K,Kikuchi K
Fri Mar 01 00:00:00 EST 2019
Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.
Brain structure & function
Otsuka S,Sakakima H,Terashi T,Takada S,Nakanishi K,Kikuchi K
Fri Mar 01 00:00:00 EST 2019
Tranilast enhances the effect of anticancer agents in osteosarcoma.
Oncology reports
Nakashima T,Nagano S,Setoguchi T,Sasaki H,Saitoh Y,Maeda S,Komiya S,Taniguchi N
Mon Jul 01 00:00:00 EDT 2019
Dissecting the Role of DDX21 in Regulating Human Cytomegalovirus Replication.
Journal of virology
Hao H,Han T,Xuan B,Sun Y,Tang S,Yue N,Qian Z
Sun Dec 15 00:00:00 EST 2019
Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis.
Cell reports
Wang Y,Guo Y,Tang C,Han X,Xu M,Sun J,Zhao Y,Zhang Y,Wang M,Cao X,Zhu X,Guo W
Tue Dec 03 00:00:00 EST 2019
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
BMC cancer
Li H,Jin X,Liu B,Zhang P,Chen W,Li Q
Thu Aug 22 00:00:00 EDT 2019
SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.
International journal of molecular sciences
Xu D,Wu L,Jiang X,Yang L,Cheng J,Chen H,Hua R,Geng G,Yang L,Li Q
Mon Mar 18 00:00:00 EDT 2019
Pharmacologic Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage.
Molecular cancer research : MCR
Buranasudja V,Doskey CM,Gibson AR,Wagner BA,Du J,Gordon DJ,Koppenhafer SL,Cullen JJ,Buettner GR
Tue Oct 01 00:00:00 EDT 2019
PARP11 regulates total levels of type-I interferon receptor IFNAR1.
Nature microbiology
Guo T,Liu J,Chen X,Jin L,Huang F,Zheng H
Fri Nov 01 00:00:00 EDT 2019
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.
Cell death & disease
Lu H,Xiao J,Ke C,Ni X,Xiu R,Tian Q,Pan H,Zou L,Wang F,Ma T,Ji X,Yuan P,Liu L,Zhang J,Jia W,Duan Q,Zhu F
Mon Aug 05 00:00:00 EDT 2019
Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.
eLife
Woo Y,Kim SJ,Suh BK,Kwak Y,Jung HJ,Nhung TTM,Mun DJ,Hong JH,Noh SJ,Kim S,Lee A,Baek ST,Nguyen MD,Choe Y,Park SK
Mon Dec 09 00:00:00 EST 2019
Simultaneous targeting of XPO1 and BCL2 as an effective treatment strategy for double-hit lymphoma.
Journal of hematology & oncology
Liu Y,Azizian NG,Dou Y,Pham LV,Li Y
Thu Nov 21 00:00:00 EST 2019
Synaptic Injury in the Thalamus Accompanies White Matter Injury in Hypoxia/Ischemia-Mediated Brain Injury in Neonatal Rats.
BioMed research international
Liu N,Tong X,Huang W,Fu J,Xue X
Thu Mar 26 00:00:00 EDT 2020
CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Theranostics
Lian YF,Huang YL,Zhang YJ,Chen DM,Wang JL,Wei H,Bi YH,Jiang ZW,Li P,Chen MS,Huang YH
Mon Sep 14 00:00:00 EDT 2020
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP.
Nature microbiology
Guo T,Zuo Y,Qian L,Liu J,Yuan Y,Xu K,Miao Y,Feng Q,Chen X,Jin L,Zhang L,Dong C,Xiong S,Zheng H
Fri Nov 01 00:00:00 EDT 2019
Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.
Cell communication and signaling : CCS
Hanáková K,Bernatík O,Kravec M,Micka M,Kumar J,Harnoš J,Ovesná P,Paclíková P,Rádsetoulal M,Potěšil D,Tripsianes K,Čajánek L,Zdráhal Z,Bryja V
Mon Dec 23 00:00:00 EST 2019
Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway.
Frontiers in microbiology
Liu T,Li X,Wu M,Qin L,Chen H,Qian P
Thu Oct 01 00:00:00 EDT 2020
DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella.
Clinical genetics
Li Y,Sha Y,Wang X,Ding L,Liu W,Ji Z,Mei L,Huang X,Lin S,Kong S,Lu J,Qin W,Zhang X,Zhuang J,Tang Y,Lu Z
Wed May 01 00:00:00 EDT 2019
Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.
Human molecular genetics
Simmons AJ,Park R,Sterling NA,Jang MH,van Deursen JMA,Yen TJ,Cho SH,Kim S
Sat Jun 01 00:00:00 EDT 2019
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Frontiers in pharmacology
Zhang J,Li L,Zhang Q,Yang X,Zhang C,Zhang X,Zhang D,Lv Y,Song H,Chen B,Liu Y,Hu J,Huang Y
Thu Oct 01 00:00:00 EDT 2020
Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation.
Frontiers in pharmacology
Zhang J,Li L,Zhang Q,Yang X,Zhang C,Zhang X,Zhang D,Lv Y,Song H,Chen B,Liu Y,Hu J,Huang Y
Thu Oct 01 00:00:00 EDT 2020
Vacuolar protein sorting 4 is required for silkworm metamorphosis.
Insect molecular biology
Xia H,Chen L,Shao D,Liu X,Wang Q,Zhu F,Guo Z,Gao L,Chen K
Tue Oct 01 00:00:00 EDT 2019
Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality.
International journal of cardiology
Liu X,Zhang S,An L,Wu J,Hu X,Lai S,Mazhar H,Zou Y,He L,Zhu H
Sun Dec 01 00:00:00 EST 2019
Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.
Journal of proteome research
Dayebgadoh G,Sardiu ME,Florens L,Washburn MP
Fri Sep 06 00:00:00 EDT 2019
Neferine in the Lotus Plumule Potentiates the Antitumor Effect of Imatinib in Primary Chronic Myeloid Leukemia Cells In Vitro.
Journal of food science
Zhang Y,Xiao Y,Dong Q,Ouyang W,Qin Q
Mon Apr 01 00:00:00 EDT 2019
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Neurological research
Terashi T,Otsuka S,Takada S,Nakanishi K,Ueda K,Sumizono M,Kikuchi K,Sakakima H
Sat Jun 01 00:00:00 EDT 2019
NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury.
American journal of physiology. Renal physiology
Xu D,Chen P,Wang B,Wang Y,Miao N,Yin F,Cheng Q,Zhou Z,Xie H,Zhou L,Liu J,Wang X,Zent R,Lu L,Zhang W
Fri Feb 01 00:00:00 EST 2019
NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury.
American journal of physiology. Renal physiology
Xu D,Chen P,Wang B,Wang Y,Miao N,Yin F,Cheng Q,Zhou Z,Xie H,Zhou L,Liu J,Wang X,Zent R,Lu L,Zhang W
Fri Feb 01 00:00:00 EST 2019
Preparation and identification of polyclonal antibody against human cytomegalovirus encoding protein UL23.
Protein expression and purification
Chai H,Wu S,Deng J,Feng L,Yang X,Ran Y,Li H
Sun Sep 01 00:00:00 EDT 2019
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.
eLife
Adams CR,Htwe HH,Marsh T,Wang AL,Montoya ML,Subbaraj L,Tward AD,Bardeesy N,Perera RM
Tue May 28 00:00:00 EDT 2019
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis.
Cell reports
Zhu Q,Ding L,Zi Z,Gao S,Wang C,Wang Y,Zhu C,Yuan Z,Wei F,Cai Q
Tue Mar 26 00:00:00 EDT 2019
m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner.
Cell death & disease
Wu R,Liu Y,Zhao Y,Bi Z,Yao Y,Liu Q,Wang F,Wang Y,Wang X
Wed Feb 20 00:00:00 EST 2019
Kinesin-6 Klp9 plays motor-dependent and -independent roles in collaboration with Kinesin-5 Cut7 and the microtubule crosslinker Ase1 in fission yeast.
Scientific reports
Yukawa M,Okazaki M,Teratani Y,Furuta K,Toda T
Tue May 14 00:00:00 EDT 2019
Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity mediated by Lonp1/Aco2/Hsp75.
Toxicon : official journal of the International Society on Toxinology
Li C,Chen W,Zheng L,Zhang B,Yang X,Zhang Q,Wang N,Wang Y,Yang J,Sha J,Zhou Z,Li X,Li Y,Shen XL
Tue Oct 01 00:00:00 EDT 2019
Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes.
Molecular biology of the cell
Colicino EG,Stevens K,Curtis E,Rathbun L,Bates M,Manikas J,Amack J,Freshour J,Hehnly H
Sat Jun 15 00:00:00 EDT 2019
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
Molecular neurobiology
Nian FS,Li LL,Cheng CY,Wu PC,Lin YT,Tang CY,Ren BS,Tai CY,Fann MJ,Kao LS,Hong CJ,Tsai JW
Sun Sep 01 00:00:00 EDT 2019
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
Developmental cell
Chang CH,Zanini M,Shirvani H,Cheng JS,Yu H,Feng CH,Mercier AL,Hung SY,Forget A,Wang CH,Cigna SM,Lu IL,Chen WY,Leboucher S,Wang WJ,Ruat M,Spassky N,Tsai JW,Ayrault O
Mon Jan 28 00:00:00 EST 2019
The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole.
The Journal of biological chemistry
Pike CM,Boyer-Andersen R,Kinch LN,Caplan JL,Neunuebel MR
Fri Apr 19 00:00:00 EDT 2019
Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor.
The international journal of biochemistry & cell biology
Yu X,Wu J,Hu M,Wu J,Zhu Q,Yang Z,Xie X,Feng YQ,Yue J
Wed May 01 00:00:00 EDT 2019
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.
Frontiers in molecular neuroscience
Chang HY,Cheng HY,Tsao AN,Liu C,Tsai JW
Tue Sep 29 00:00:00 EDT 2020
Genomic Structure of Hstx2 Modifier of Prdm9-Dependent Hybrid Male Sterility in Mice.
Genetics
Lustyk D,Kinský S,Ullrich KK,Yancoskie M,Kašíková L,Gergelits V,Sedlacek R,Chan YF,Odenthal-Hesse L,Forejt J,Jansa P
Fri Nov 01 00:00:00 EDT 2019
Proteasome inhibition promotes mono-ubiquitination and nuclear translocation of mature (52 kDa) PINK1.
Biochemical and biophysical research communications
Sun L,Büeler H
Tue Sep 17 00:00:00 EDT 2019
CXCL13/CXCR5 signaling contributes to diabetes-induced tactile allodynia via activating pERK, pSTAT3, pAKT pathways and pro-inflammatory cytokines production in the spinal cord of male mice.
Brain, behavior, and immunity
Liu S,Liu X,Xiong H,Wang W,Liu Y,Yin L,Tu C,Wang H,Xiang X,Xu J,Duan B,Tao A,Zhao Z,Mei Z
Thu Aug 01 00:00:00 EDT 2019
p53 suppression is essential for oncogenic SPAG5 upregulation in lung adenocarcinoma.
Biochemical and biophysical research communications
Wang T,Li K,Song H,Xu D,Liao Y,Jing B,Guo W,Hu M,Kuang Y,Sun B,Ling J,Zhang T,Xu J,Yao F,Deng J
Tue May 28 00:00:00 EDT 2019
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade.
International journal of molecular sciences
Tsai YT,Wu AC,Yang WB,Kao TJ,Chuang JY,Chang WC,Hsu TI
Mon Nov 11 00:00:00 EST 2019
SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
Life sciences
Xu D,Jiang X,He H,Liu D,Yang L,Chen H,Wu L,Geng G,Li Q
Sun Sep 01 00:00:00 EDT 2019
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models.
Scientific reports
Vauthier V,Ben Saad A,Elie J,Oumata N,Durand-Schneider AM,Bruneau A,Delaunay JL,Housset C,Aït-Slimane T,Meijer L,Falguières T
Tue Apr 30 00:00:00 EDT 2019
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Scientific reports
Martin-Hurtado A,Martin-Morales R,Robledinos-Antón N,Blanco R,Palacios-Blanco I,Lastres-Becker I,Cuadrado A,Garcia-Gonzalo FR
Wed Sep 25 00:00:00 EDT 2019
Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.
Virology
Wen W,Yin M,Zhang H,Liu T,Chen H,Qian P,Hu J,Li X
Sun Sep 01 00:00:00 EDT 2019
Silver nanoparticles selectively induce human oncogenic γ-herpesvirus-related cancer cell death through reactivating viral lytic replication.
Cell death & disease
Wan C,Tai J,Zhang J,Guo Y,Zhu Q,Ling D,Gu F,Gan J,Zhu C,Wang Y,Liu S,Wei F,Cai Q
Tue May 21 00:00:00 EDT 2019
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
Nature medicine
Ji YX,Huang Z,Yang X,Wang X,Zhao LP,Wang PX,Zhang XJ,Alves-Bezerra M,Cai L,Zhang P,Lu YX,Bai L,Gao MM,Zhao H,Tian S,Wang Y,Huang ZX,Zhu XY,Zhang Y,Gong J,She ZG,Li F,Cohen DE,Li H
Thu Feb 01 00:00:00 EST 2018
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
Nature medicine
Ji YX,Huang Z,Yang X,Wang X,Zhao LP,Wang PX,Zhang XJ,Alves-Bezerra M,Cai L,Zhang P,Lu YX,Bai L,Gao MM,Zhao H,Tian S,Wang Y,Huang ZX,Zhu XY,Zhang Y,Gong J,She ZG,Li F,Cohen DE,Li H
Thu Feb 01 00:00:00 EST 2018
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Cancer cell
Zhu D,Osuka S,Zhang Z,Reichert ZR,Yang L,Kanemura Y,Jiang Y,You S,Zhang H,Devi NS,Bhattacharya D,Takano S,Gillespie GY,Macdonald T,Tan C,Nishikawa R,Nelson WG,Olson JJ,Van Meir EG
Mon Jun 11 00:00:00 EDT 2018
BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Cancer cell
Zhu D,Osuka S,Zhang Z,Reichert ZR,Yang L,Kanemura Y,Jiang Y,You S,Zhang H,Devi NS,Bhattacharya D,Takano S,Gillespie GY,Macdonald T,Tan C,Nishikawa R,Nelson WG,Olson JJ,Van Meir EG
Mon Jun 11 00:00:00 EDT 2018
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Cell metabolism
Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC
Tue Apr 03 00:00:00 EDT 2018
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Cell metabolism
Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC
Tue Apr 03 00:00:00 EDT 2018
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Cell metabolism
McWilliams TG,Prescott AR,Montava-Garriga L,Ball G,Singh F,Barini E,Muqit MMK,Brooks SP,Ganley IG
Tue Feb 06 00:00:00 EST 2018
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Cell metabolism
McWilliams TG,Prescott AR,Montava-Garriga L,Ball G,Singh F,Barini E,Muqit MMK,Brooks SP,Ganley IG
Tue Feb 06 00:00:00 EST 2018
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Molecular cell
Wen J,Lv R,Ma H,Shen H,He C,Wang J,Jiao F,Liu H,Yang P,Tan L,Lan F,Shi YG,He C,Shi Y,Diao J
Thu Mar 15 00:00:00 EDT 2018
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Molecular cell
Wen J,Lv R,Ma H,Shen H,He C,Wang J,Jiao F,Liu H,Yang P,Tan L,Lan F,Shi YG,He C,Shi Y,Diao J
Thu Mar 15 00:00:00 EDT 2018
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.
Proceedings of the National Academy of Sciences of the United States of America
Kincaid RP,Lam VL,Chirayil RP,Randall G,Sullivan CS
Tue Aug 07 00:00:00 EDT 2018
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.
Proceedings of the National Academy of Sciences of the United States of America
Kincaid RP,Lam VL,Chirayil RP,Randall G,Sullivan CS
Tue Aug 07 00:00:00 EDT 2018
The Protective Role of Brain CYP2J in Parkinson's Disease Models.
Oxidative medicine and cellular longevity
Li Y,Wu J,Yu X,Na S,Li K,Yang Z,Xie X,Yang J,Yue J
Mon Oct 22 00:00:00 EDT 2018
The Protective Role of Brain CYP2J in Parkinson's Disease Models.
Oxidative medicine and cellular longevity
Li Y,Wu J,Yu X,Na S,Li K,Yang Z,Xie X,Yang J,Yue J
Mon Oct 22 00:00:00 EDT 2018
Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents.
European journal of medicinal chemistry
Zhang L,Zhao Y,Wang J,Yang D,Zhao C,Wang C,Ma C,Cheng M
Thu May 10 00:00:00 EDT 2018
Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents.
European journal of medicinal chemistry
Zhang L,Zhao Y,Wang J,Yang D,Zhao C,Wang C,Ma C,Cheng M
Thu May 10 00:00:00 EDT 2018
Murine Cytomegalovirus Protein pM91 Interacts with pM79 and Is Critical for Viral Late Gene Expression.
Journal of virology
Pan D,Han T,Tang S,Xu W,Bao Q,Sun Y,Xuan B,Qian Z
Sat Sep 15 00:00:00 EDT 2018
Murine Cytomegalovirus Protein pM91 Interacts with pM79 and Is Critical for Viral Late Gene Expression.
Journal of virology
Pan D,Han T,Tang S,Xu W,Bao Q,Sun Y,Xuan B,Qian Z
Sat Sep 15 00:00:00 EDT 2018
PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.
Journal of cellular physiology
Liu Y,Wang JX,Huang D,Wang B,Li LL,Li XX,Ni P,Dong XL,Xia W,Yu CX,Xu WL,Chu WF,Zhao D
Sat Dec 01 00:00:00 EST 2018
PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.
Journal of cellular physiology
Liu Y,Wang JX,Huang D,Wang B,Li LL,Li XX,Ni P,Dong XL,Xia W,Yu CX,Xu WL,Chu WF,Zhao D
Sat Dec 01 00:00:00 EST 2018
Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity.
Frontiers in molecular neuroscience
Chen YA,Lu IL,Tsai JW
Thu Oct 01 00:00:00 EDT 2020
Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity.
Frontiers in molecular neuroscience
Chen YA,Lu IL,Tsai JW
Thu Oct 01 00:00:00 EDT 2020
mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells.
Molecular cancer therapeutics
Koppenhafer SL,Goss KL,Terry WW,Gordon DJ
Sat Dec 01 00:00:00 EST 2018
mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells.
Molecular cancer therapeutics
Koppenhafer SL,Goss KL,Terry WW,Gordon DJ
Sat Dec 01 00:00:00 EST 2018
Deletion of the stress-response protein REDD1 promotes ceramide-induced retinal cell death and JNK activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dai W,Miller WP,Toro AL,Black AJ,Dierschke SK,Feehan RP,Kimball SR,Dennis MD
Tue Jun 19 00:00:00 EDT 2018
Deletion of the stress-response protein REDD1 promotes ceramide-induced retinal cell death and JNK activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dai W,Miller WP,Toro AL,Black AJ,Dierschke SK,Feehan RP,Kimball SR,Dennis MD
Tue Jun 19 00:00:00 EDT 2018
AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang P,Song Y,Sun Y,Li X,Chen L,Yang L,Xing Y
Sun Jul 01 00:00:00 EDT 2018
AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang P,Song Y,Sun Y,Li X,Chen L,Yang L,Xing Y
Sun Jul 01 00:00:00 EDT 2018
UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment.
Molecular neurobiology
Yu Q,Zhang H,Li Y,Liu C,Wang S,Liao X
Tue May 01 00:00:00 EDT 2018
UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment.
Molecular neurobiology
Yu Q,Zhang H,Li Y,Liu C,Wang S,Liao X
Tue May 01 00:00:00 EDT 2018
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Systematic In-Depth Proteomic Analysis of Mitochondria-Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes.
Proteomics
Wang X,Wen Y,Dong J,Cao C,Yuan S
Sun Jul 01 00:00:00 EDT 2018
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Journal of cell science
Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW
Mon Dec 17 00:00:00 EST 2018
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Journal of cell science
Hsiao CJ,Chang CH,Ibrahim RB,Lin IH,Wang CH,Wang WJ,Tsai JW
Mon Dec 17 00:00:00 EST 2018
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Journal of physiology and biochemistry
Chen C,Deng Y,Hu X,Ren H,Zhu J,Fu S,Xie J,Peng Y
Wed Aug 01 00:00:00 EDT 2018
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Journal of physiology and biochemistry
Chen C,Deng Y,Hu X,Ren H,Zhu J,Fu S,Xie J,Peng Y
Wed Aug 01 00:00:00 EDT 2018
ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.
Journal of cellular biochemistry
Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D
Sun Apr 01 00:00:00 EDT 2018
ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation.
Journal of cellular biochemistry
Ma Y,Yuan S,Tian X,Lin S,Wei S,Hu T,Chen S,Li X,Chen S,Wu D,Wang M,Guo D
Sun Apr 01 00:00:00 EDT 2018
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
DNA and cell biology
Cui X,Zhou Z,Zhu K,Feng R,Han J,Li M,Wang S,Li J,Zhang J,Jiang Q,Zhang W,Mu H,Liu Y,Hu Y
Tue May 01 00:00:00 EDT 2018
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
DNA and cell biology
Cui X,Zhou Z,Zhu K,Feng R,Han J,Li M,Wang S,Li J,Zhang J,Jiang Q,Zhang W,Mu H,Liu Y,Hu Y
Tue May 01 00:00:00 EDT 2018
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Biochemical and biophysical research communications
Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H
Fri Apr 06 00:00:00 EDT 2018
Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.
Biochemical and biophysical research communications
Qian G,Hu X,Li G,Ding Y,Zhu L,Zheng H,Li M,Li Z,Pan J,Li Y,Li G,Yang C,Liu Y,Xie Y,Lv H
Fri Apr 06 00:00:00 EDT 2018
MCPIP1 is a positive regulator of type I interferons antiviral activity.
Biochemical and biophysical research communications
Qian L,Zuo Y,Deng W,Miao Y,Liu J,Yuan Y,Guo T,Zhang L,Jin J,Wang J,Zheng H
Sun Apr 15 00:00:00 EDT 2018
MCPIP1 is a positive regulator of type I interferons antiviral activity.
Biochemical and biophysical research communications
Qian L,Zuo Y,Deng W,Miao Y,Liu J,Yuan Y,Guo T,Zhang L,Jin J,Wang J,Zheng H
Sun Apr 15 00:00:00 EDT 2018
Ifi27 is indispensable for mitochondrial function and browning in adipocytes.
Biochemical and biophysical research communications
Jin W,Jin W,Pan D
Mon Jun 18 00:00:00 EDT 2018
Ifi27 is indispensable for mitochondrial function and browning in adipocytes.
Biochemical and biophysical research communications
Jin W,Jin W,Pan D
Mon Jun 18 00:00:00 EDT 2018
Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.
Biochemical and biophysical research communications
Jheng GW,Hur SS,Chang CM,Wu CC,Cheng JS,Lee HH,Chung BC,Wang YK,Lin KH,Del Álamo JC,Chien S,Tsai JW
Sun Mar 11 00:00:00 EST 2018
Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.
Biochemical and biophysical research communications
Jheng GW,Hur SS,Chang CM,Wu CC,Cheng JS,Lee HH,Chung BC,Wang YK,Lin KH,Del Álamo JC,Chien S,Tsai JW
Sun Mar 11 00:00:00 EST 2018
Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling.
Evidence-based complementary and alternative medicine : eCAM
Tang Y,Huang W,Song Q,Zheng X,He R,Liu J
Sat Apr 09 00:00:00 EDT 2022
Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling.
Evidence-based complementary and alternative medicine : eCAM
Tang Y,Huang W,Song Q,Zheng X,He R,Liu J
Sat Apr 09 00:00:00 EDT 2022
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Frontiers in immunology
Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H
Fri Oct 25 00:00:00 EDT 2019
β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling.
Frontiers in immunology
Liu J,Yuan Y,Xu J,Xiao K,Xu Y,Guo T,Zhang L,Wang J,Zheng H
Fri Oct 25 00:00:00 EDT 2019
MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.
Cell death & disease
Dang Y,Wang X,Hao Y,Zhang X,Zhao S,Ma J,Qin Y,Chen ZJ
Wed Jan 24 00:00:00 EST 2018
MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.
Cell death & disease
Dang Y,Wang X,Hao Y,Zhang X,Zhao S,Ma J,Qin Y,Chen ZJ
Wed Jan 24 00:00:00 EST 2018
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Cell death & disease
Huang Y,Wang H,Lian Y,Wu X,Zhou L,Wang J,Deng M,Huang Y
Fri Feb 02 00:00:00 EST 2018
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma.
Cell death & disease
Huang Y,Wang H,Lian Y,Wu X,Zhou L,Wang J,Deng M,Huang Y
Fri Feb 02 00:00:00 EST 2018
A growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5+ intestinal stem cell maintenance.
Cell discovery
Li Y,Liu Y,Liu B,Wang J,Wei S,Qi Z,Wang S,Fu W,Chen YG
Thu Oct 01 00:00:00 EDT 2020
A growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5+ intestinal stem cell maintenance.
Cell discovery
Li Y,Liu Y,Liu B,Wang J,Wei S,Qi Z,Wang S,Fu W,Chen YG
Thu Oct 01 00:00:00 EDT 2020
High-Content Screening of a Taiwanese Indigenous Plant Extract Library Identifies Syzygium simile leaf Extract as an Inhibitor of Fatty Acid Uptake.
International journal of molecular sciences
Yen CH,Chang HS,Yang TH,Wang SF,Wu HC,Chen YC,Lin KJ,Wang S
Sun Jul 22 00:00:00 EDT 2018
High-Content Screening of a Taiwanese Indigenous Plant Extract Library Identifies Syzygium simile leaf Extract as an Inhibitor of Fatty Acid Uptake.
International journal of molecular sciences
Yen CH,Chang HS,Yang TH,Wang SF,Wu HC,Chen YC,Lin KJ,Wang S
Sun Jul 22 00:00:00 EDT 2018
CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.
International journal of molecular sciences
Shi WP,Ju D,Li H,Yuan L,Cui J,Luo D,Chen ZN,Bian H
Tue Apr 10 00:00:00 EDT 2018
CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.
International journal of molecular sciences
Shi WP,Ju D,Li H,Yuan L,Cui J,Luo D,Chen ZN,Bian H
Tue Apr 10 00:00:00 EDT 2018
EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.
Cell death & disease
Peng Q,Chen L,Wu W,Wang J,Zheng X,Chen Z,Jiang Q,Han J,Wei L,Wang L,Huang J,Ma J
Mon Nov 19 00:00:00 EST 2018
EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.
Cell death & disease
Peng Q,Chen L,Wu W,Wang J,Zheng X,Chen Z,Jiang Q,Han J,Wei L,Wang L,Huang J,Ma J
Mon Nov 19 00:00:00 EST 2018
Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.
The Journal of biological chemistry
Mana-Capelli S,McCollum D
Fri Nov 23 00:00:00 EST 2018
Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.
The Journal of biological chemistry
Mana-Capelli S,McCollum D
Fri Nov 23 00:00:00 EST 2018
Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.
EBioMedicine
Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W
Fri Jun 01 00:00:00 EDT 2018
Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.
EBioMedicine
Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W
Fri Jun 01 00:00:00 EDT 2018
Quercetin attenuates AZT-induced neuroinflammation in the CNS.
Scientific reports
Yang Y,Liu X,Wu T,Zhang W,Shu J,He Y,Tang SJ
Wed Apr 18 00:00:00 EDT 2018
Quercetin attenuates AZT-induced neuroinflammation in the CNS.
Scientific reports
Yang Y,Liu X,Wu T,Zhang W,Shu J,He Y,Tang SJ
Wed Apr 18 00:00:00 EDT 2018
ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3.
Journal of immunology (Baltimore, Md. : 1950)
Feng Q,Miao Y,Ge J,Yuan Y,Zuo Y,Qian L,Liu J,Cheng Q,Guo T,Zhang L,Yu Z,Zheng H
Sun Jul 15 00:00:00 EDT 2018
Legumain, an asparaginyl endopeptidase, mediates the effect of M2 macrophages on attenuating renal interstitial fibrosis in obstructive nephropathy.
Kidney international
Wang D,Xiong M,Chen C,Du L,Liu Z,Shi Y,Zhang M,Gong J,Song X,Xiang R,Liu E,Tan X
Sun Jul 01 00:00:00 EDT 2018
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
FEBS letters
Jiang D,Zou X,Zhang C,Chen J,Li Z,Wang Y,Deng Z,Wang L,Chen S
Sun Apr 01 00:00:00 EDT 2018
Low-dose paclitaxel downregulates MYC proto-oncogene bHLH transcription factor expression in colorectal carcinoma cells.
Oncology letters
Li W,Zhu W,Lv C,Qu H,Xu K,Li H,Li H,Du Y,Liu G,Wang Y,Wei HJ,Zhao HY
Thu Feb 01 00:00:00 EST 2018
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
Aging
Lian YF,Huang YL,Wang JL,Deng MH,Xia TL,Zeng MS,Chen MS,Wang HB,Huang YH
Thu Aug 09 00:00:00 EDT 2018
Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma.
Aging
Lian YF,Huang YL,Wang JL,Deng MH,Xia TL,Zeng MS,Chen MS,Wang HB,Huang YH
Thu Aug 09 00:00:00 EDT 2018
Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy.
Drug design, development and therapy
Zhang M,Yan Z,Bu L,An C,Wang D,Liu X,Zhang J,Yang W,Deng B,Xie J,Zhang B
Mon Oct 29 00:00:00 EDT 2018
Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy.
Drug design, development and therapy
Zhang M,Yan Z,Bu L,An C,Wang D,Liu X,Zhang J,Yang W,Deng B,Xie J,Zhang B
Mon Oct 29 00:00:00 EDT 2018
Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.
Science China. Life sciences
Wang L,Liu L,Qin L,Luo Q,Zhang Z
Sat Apr 01 00:00:00 EDT 2017
Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.
Science China. Life sciences
Wang L,Liu L,Qin L,Luo Q,Zhang Z
Sat Apr 01 00:00:00 EDT 2017
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Antiviral research
Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H
Tue Aug 01 00:00:00 EDT 2017
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Antiviral research
Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H
Tue Aug 01 00:00:00 EDT 2017
Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.
Journal of virology
Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE
Fri Dec 15 00:00:00 EST 2017
Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription.
Journal of virology
Cifuentes-Muñoz N,Branttie J,Slaughter KB,Dutch RE
Fri Dec 15 00:00:00 EST 2017
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
International journal of molecular medicine
Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J
Wed Nov 01 00:00:00 EDT 2017
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
International journal of molecular medicine
Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J
Wed Nov 01 00:00:00 EDT 2017
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
International journal of molecular medicine
Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J
Wed Nov 01 00:00:00 EDT 2017
MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3.
International journal of molecular medicine
Bian H,Li F,Wang W,Zhao Q,Gao S,Ma J,Li X,Ren W,Qin C,Qi J
Wed Nov 01 00:00:00 EDT 2017
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
Journal of cellular and molecular medicine
Tang H,Lei CT,Ye C,Gao P,Wan C,Chen S,He FF,Wang YM,Su H,Zhang C
Fri Dec 01 00:00:00 EST 2017
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
Journal of cellular and molecular medicine
Tang H,Lei CT,Ye C,Gao P,Wan C,Chen S,He FF,Wang YM,Su H,Zhang C
Fri Dec 01 00:00:00 EST 2017
Antithrombin III prevents progression of chronic kidney disease following experimental ischaemic-reperfusion injury.
Journal of cellular and molecular medicine
Yin J,Wang F,Kong Y,Wu R,Zhang G,Wang N,Wang L,Lu Z,Liang M
Fri Dec 01 00:00:00 EST 2017
Antithrombin III prevents progression of chronic kidney disease following experimental ischaemic-reperfusion injury.
Journal of cellular and molecular medicine
Yin J,Wang F,Kong Y,Wu R,Zhang G,Wang N,Wang L,Lu Z,Liang M
Fri Dec 01 00:00:00 EST 2017
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Human molecular genetics
Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J
Fri Dec 15 00:00:00 EST 2017
De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.
Human molecular genetics
Slavotinek A,Risolino M,Losa M,Cho MT,Monaghan KG,Schneidman-Duhovny D,Parisotto S,Herkert JC,Stegmann APA,Miller K,Shur N,Chui J,Muller E,DeBrosse S,Szot JO,Chapman G,Pachter NS,Winlaw DS,Mendelsohn BA,Dalton J,Sarafoglou K,Karachunski PI,Lewis JM,Pedro H,Dunwoodie SL,Selleri L,Shieh J
Fri Dec 15 00:00:00 EST 2017
IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.
Endocrinology
Dang X,Zhu Q,He Y,Wang Y,Lu Y,Li X,Qi J,Wu H,Sun Y
Sun Oct 01 00:00:00 EDT 2017
IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.
Endocrinology
Dang X,Zhu Q,He Y,Wang Y,Lu Y,Li X,Qi J,Wu H,Sun Y
Sun Oct 01 00:00:00 EDT 2017
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Molecular immunology
Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P
Wed Feb 01 00:00:00 EST 2017
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Molecular immunology
Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P
Wed Feb 01 00:00:00 EST 2017
HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells.
Experimental cell research
Shang Y,Chen H,Ye J,Wei X,Liu S,Wang R
Wed Nov 15 00:00:00 EST 2017
HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells.
Experimental cell research
Shang Y,Chen H,Ye J,Wei X,Liu S,Wang R
Wed Nov 15 00:00:00 EST 2017
Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.
Molecular medicine reports
Wang Y,Gu YH,Liu M,Bai Y,Wang HL
Wed Feb 01 00:00:00 EST 2017
Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.
Molecular medicine reports
Wang Y,Gu YH,Liu M,Bai Y,Wang HL
Wed Feb 01 00:00:00 EST 2017
Hydrogen peroxide promotes the expression of angiopoietin like 4 in RAW264.7 macrophages via MAPK pathways.
Molecular medicine reports
Liu N,Cui C,Sun Y,Zhang F,Wang S,Su G,Cai X
Wed Nov 01 00:00:00 EDT 2017
Co-expression of podoplanin and fibroblast growth factor 1 predicts poor prognosis in patients with lung squamous cell carcinoma.
Molecular medicine reports
Li J,Chen H,Li X,Wang L,Gao A,Zhang P,Lin W,Gao W,Yang D,Guo X,Liu J,Dang Q,Sun Y
Tue Aug 01 00:00:00 EDT 2017
Co-expression of podoplanin and fibroblast growth factor 1 predicts poor prognosis in patients with lung squamous cell carcinoma.
Molecular medicine reports
Li J,Chen H,Li X,Wang L,Gao A,Zhang P,Lin W,Gao W,Yang D,Guo X,Liu J,Dang Q,Sun Y
Tue Aug 01 00:00:00 EDT 2017
CMIP Promotes Proliferation and Metastasis in Human Glioma.
BioMed research international
Wang B,Wu ZS,Wu Q
Mon Apr 16 00:00:00 EDT 2018
CMIP Promotes Proliferation and Metastasis in Human Glioma.
BioMed research international
Wang B,Wu ZS,Wu Q
Mon Apr 16 00:00:00 EDT 2018
Tectorigenin attenuates the MPP+-induced SH-SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition.
Experimental and therapeutic medicine
Gong P,Deng F,Zhang W,Ji J,Liu J,Sun Y,Hu J
Wed Nov 01 00:00:00 EDT 2017
Tectorigenin attenuates the MPP+-induced SH-SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition.
Experimental and therapeutic medicine
Gong P,Deng F,Zhang W,Ji J,Liu J,Sun Y,Hu J
Wed Nov 01 00:00:00 EDT 2017
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Scientific reports
Pirone L,Xolalpa W,Sigurðsson JO,Ramirez J,Pérez C,González M,de Sabando AR,Elortza F,Rodriguez MS,Mayor U,Olsen JV,Barrio R,Sutherland JD
Wed Jan 18 00:00:00 EST 2017
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation.
Scientific reports
Pirone L,Xolalpa W,Sigurðsson JO,Ramirez J,Pérez C,González M,de Sabando AR,Elortza F,Rodriguez MS,Mayor U,Olsen JV,Barrio R,Sutherland JD
Wed Jan 18 00:00:00 EST 2017
Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine.
Oncotarget
Goss KL,Koppenhafer SL,Harmoney KM,Terry WW,Gordon DJ
Fri Oct 20 00:00:00 EDT 2017
Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.
Scientific reports
Zhang C,Mao HL,Cao Y
Mon Jun 19 00:00:00 EDT 2017
Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.
Scientific reports
Zhang C,Mao HL,Cao Y
Mon Jun 19 00:00:00 EDT 2017
Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts.
Scientific reports
Liu X,Zuo R,Bao Y,Qu X,Sun K,Ying H
Wed Aug 16 00:00:00 EDT 2017
Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts.
Scientific reports
Liu X,Zuo R,Bao Y,Qu X,Sun K,Ying H
Wed Aug 16 00:00:00 EDT 2017
SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis.
Molecular cancer
Yuan H,Deng R,Zhao X,Chen R,Hou G,Zhang H,Wang Y,Xu M,Jiang B,Yu J
Wed Oct 11 00:00:00 EDT 2017
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.
Open biology
Ma P,Ren B,Yang X,Sun B,Liu X,Kong Q,Li C,Mao B
Tue Aug 01 00:00:00 EDT 2017
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.
Open biology
Ma P,Ren B,Yang X,Sun B,Liu X,Kong Q,Li C,Mao B
Tue Aug 01 00:00:00 EDT 2017
Identification and Characterization of BmVta1, a Bombyx mori (Lepidoptera: Bombycidae) Homologue for Vta1 That is Up-Regulated in Development.
Journal of insect science (Online)
Xia H,Shao D,Liu X,Wang Q,Zhou Y,Chen K
Mon May 01 00:00:00 EDT 2017
Identification and Characterization of BmVta1, a Bombyx mori (Lepidoptera: Bombycidae) Homologue for Vta1 That is Up-Regulated in Development.
Journal of insect science (Online)
Xia H,Shao D,Liu X,Wang Q,Zhou Y,Chen K
Mon May 01 00:00:00 EDT 2017
Suppression of nuclear factor erythroid‑2‑related factor 2‑mediated antioxidative defense in the lung injury induced by chronic exposure to methamphetamine in rats.
Molecular medicine reports
Bai Y,Wang Y,Liu M,Gu YH,Jiang B,Wu X,Wang HL
Mon May 01 00:00:00 EDT 2017
Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner.
Frontiers in cellular and infection microbiology
Allgood SC,Romero Dueñas BP,Noll RR,Pike C,Lein S,Neunuebel MR
Fri May 18 00:00:00 EDT 2018
Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner.
Frontiers in cellular and infection microbiology
Allgood SC,Romero Dueñas BP,Noll RR,Pike C,Lein S,Neunuebel MR
Fri May 18 00:00:00 EDT 2018
A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis.
eLife
Wang Z,Xia X,Yang X,Zhang X,Liu Y,Wu D,Fang Y,Liu Y,Xu J,Qiu Y,Zhou X
Tue Dec 12 00:00:00 EST 2017
A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis.
eLife
Wang Z,Xia X,Yang X,Zhang X,Liu Y,Wu D,Fang Y,Liu Y,Xu J,Qiu Y,Zhou X
Tue Dec 12 00:00:00 EST 2017
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Cell death & disease
Xie P,Yang JP,Cao Y,Peng LX,Zheng LS,Sun R,Meng DF,Wang MY,Mei Y,Qiang YY,Cao L,Xiang YQ,Luo DH,Yun JP,Huang BJ,Jia LJ,Qian CN
Thu Jun 01 00:00:00 EDT 2017
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Cell death & disease
Xie P,Yang JP,Cao Y,Peng LX,Zheng LS,Sun R,Meng DF,Wang MY,Mei Y,Qiang YY,Cao L,Xiang YQ,Luo DH,Yun JP,Huang BJ,Jia LJ,Qian CN
Thu Jun 01 00:00:00 EDT 2017
The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.
The Journal of biological chemistry
de Castro RO,Previato L,Goitea V,Felberg A,Guiraldelli MF,Filiberti A,Pezza RJ
Fri May 19 00:00:00 EDT 2017
The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.
The Journal of biological chemistry
de Castro RO,Previato L,Goitea V,Felberg A,Guiraldelli MF,Filiberti A,Pezza RJ
Fri May 19 00:00:00 EDT 2017
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zuo T,Zhu M,Xu W,Wang Z,Song H
Mon Jan 22 00:00:00 EST 2018
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zuo T,Zhu M,Xu W,Wang Z,Song H
Mon Jan 22 00:00:00 EST 2018
Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Yu H,Zhang X,Liu R,Li H,Xiao X,Zhou Y,Wei C,Yang M,Liao M,Zhao J,Xia Z,Liao Q
Sat Jul 01 00:00:00 EDT 2017
Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Yu H,Zhang X,Liu R,Li H,Xiao X,Zhou Y,Wei C,Yang M,Liao M,Zhao J,Xia Z,Liao Q
Sat Jul 01 00:00:00 EDT 2017
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.
Nature communications
Liu G,Zhou L,Zhang H,Chen R,Zhang Y,Li L,Lu JY,Jiang H,Liu D,Qi S,Jiang YM,Yin K,Xie Z,Shi Y,Liu Y,Cao X,Chen YX,Zou D,Zhang WJ
Wed Mar 22 00:00:00 EDT 2017
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.
Nature communications
Liu G,Zhou L,Zhang H,Chen R,Zhang Y,Li L,Lu JY,Jiang H,Liu D,Qi S,Jiang YM,Yin K,Xie Z,Shi Y,Liu Y,Cao X,Chen YX,Zou D,Zhang WJ
Wed Mar 22 00:00:00 EDT 2017
NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival.
Scientific reports
Nakano M,Tamura Y,Yamato M,Kume S,Eguchi A,Takata K,Watanabe Y,Kataoka Y
Tue Feb 14 00:00:00 EST 2017
NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival.
Scientific reports
Nakano M,Tamura Y,Yamato M,Kume S,Eguchi A,Takata K,Watanabe Y,Kataoka Y
Tue Feb 14 00:00:00 EST 2017
Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling.
Scientific reports
Wu T,Zhang J,Geng M,Tang SJ,Zhang W,Shu J
Fri Jun 23 00:00:00 EDT 2017
Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling.
Scientific reports
Wu T,Zhang J,Geng M,Tang SJ,Zhang W,Shu J
Fri Jun 23 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Journal of hematology & oncology
Yu Z,Sun Y,She X,Wang Z,Chen S,Deng Z,Zhang Y,Liu Q,Liu Q,Zhao C,Li P,Liu C,Feng J,Fu H,Li G,Wu M
Thu Jun 08 00:00:00 EDT 2017
TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling.
Oncotarget
Wang JL,Qi Z,Li YH,Zhao HM,Chen YG,Fu W
Tue Sep 19 00:00:00 EDT 2017
TGFβ induced factor homeobox 1 promotes colorectal cancer development through activating Wnt/β-catenin signaling.
Oncotarget
Wang JL,Qi Z,Li YH,Zhao HM,Chen YG,Fu W
Tue Sep 19 00:00:00 EDT 2017
HTLV-1 Tax upregulates early growth response protein 1 through nuclear factor-κB signaling.
Oncotarget
Huang Q,Niu Z,Han J,Liu X,Lv Z,Li H,Yuan L,Li X,Sun S,Wang H,Huang X
Tue Aug 01 00:00:00 EDT 2017
MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors.
Scientific reports
Ji HP,Xiong Y,Song WT,Zhang ED,Gao ZL,Yao F,Su T,Zhou RR,Xia XB
Tue Sep 12 00:00:00 EDT 2017
MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors.
Scientific reports
Ji HP,Xiong Y,Song WT,Zhang ED,Gao ZL,Yao F,Su T,Zhou RR,Xia XB
Tue Sep 12 00:00:00 EDT 2017
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.
Nature chemical biology
Theodoropoulos PC,Gonzales SS,Winterton SE,Rodriguez-Navas C,McKnight JS,Morlock LK,Hanson JM,Cross B,Owen AE,Duan Y,Moreno JR,Lemoff A,Mirzaei H,Posner BA,Williams NS,Ready JM,Nijhawan D
Fri Apr 01 00:00:00 EDT 2016
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.
Nature chemical biology
Theodoropoulos PC,Gonzales SS,Winterton SE,Rodriguez-Navas C,McKnight JS,Morlock LK,Hanson JM,Cross B,Owen AE,Duan Y,Moreno JR,Lemoff A,Mirzaei H,Posner BA,Williams NS,Ready JM,Nijhawan D
Fri Apr 01 00:00:00 EDT 2016
State estimation and prediction using clustered particle filters.
Proceedings of the National Academy of Sciences of the United States of America
Lee Y,Majda AJ
Tue Dec 20 00:00:00 EST 2016
State estimation and prediction using clustered particle filters.
Proceedings of the National Academy of Sciences of the United States of America
Lee Y,Majda AJ
Tue Dec 20 00:00:00 EST 2016
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
Proceedings of the National Academy of Sciences of the United States of America
Mukhopadhyay C,Triplett A,Bargar T,Heckman C,Wagner KU,Naramura M
Tue Dec 20 00:00:00 EST 2016
Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation.
Proceedings of the National Academy of Sciences of the United States of America
Mukhopadhyay C,Triplett A,Bargar T,Heckman C,Wagner KU,Naramura M
Tue Dec 20 00:00:00 EST 2016
Suberoylanilide hydroxamic acid represses glioma stem-like cells.
Journal of biomedical science
Hsu CC,Chang WC,Hsu TI,Liu JJ,Yeh SH,Wang JY,Liou JP,Ko CY,Chang KY,Chuang JY
Fri Nov 18 00:00:00 EST 2016
Suberoylanilide hydroxamic acid represses glioma stem-like cells.
Journal of biomedical science
Hsu CC,Chang WC,Hsu TI,Liu JJ,Yeh SH,Wang JY,Liou JP,Ko CY,Chang KY,Chuang JY
Fri Nov 18 00:00:00 EST 2016
Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.
PLoS pathogens
El Najjar F,Cifuentes-Muñoz N,Chen J,Zhu H,Buchholz UJ,Moncman CL,Dutch RE
Thu Sep 01 00:00:00 EDT 2016
Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.
PLoS pathogens
El Najjar F,Cifuentes-Muñoz N,Chen J,Zhu H,Buchholz UJ,Moncman CL,Dutch RE
Thu Sep 01 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
Insulin deficiency induces rat renal mesangial cell dysfunction via activation of IGF-1/IGF-1R pathway.
Acta pharmacologica Sinica
Kong YL,Shen Y,Ni J,Shao DC,Miao NJ,Xu JL,Zhou L,Xue H,Zhang W,Wang XX,Lu LM
Mon Feb 01 00:00:00 EST 2016
Insulin deficiency induces rat renal mesangial cell dysfunction via activation of IGF-1/IGF-1R pathway.
Acta pharmacologica Sinica
Kong YL,Shen Y,Ni J,Shao DC,Miao NJ,Xu JL,Zhou L,Xue H,Zhang W,Wang XX,Lu LM
Mon Feb 01 00:00:00 EST 2016
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Oncogenesis
Chen B,Liu J,Ho TT,Ding X,Mo YY
Mon Dec 12 00:00:00 EST 2016
ERK-mediated NF-κB activation through ASIC1 in response to acidosis.
Oncogenesis
Chen B,Liu J,Ho TT,Ding X,Mo YY
Mon Dec 12 00:00:00 EST 2016
Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.
World journal of gastroenterology
Li Y,Liu YH,Hu YY,Chen L,Li JM
Fri Oct 14 00:00:00 EDT 2016
Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells.
World journal of gastroenterology
Li Y,Liu YH,Hu YY,Chen L,Li JM
Fri Oct 14 00:00:00 EDT 2016
Influence of miR-30b regulating humoral immune response by genetic difference.
Immunologic research
Duan ZQ,Shi JD,Wu MN,Hu NZ,Hu YZ
Mon Feb 01 00:00:00 EST 2016
Influence of miR-30b regulating humoral immune response by genetic difference.
Immunologic research
Duan ZQ,Shi JD,Wu MN,Hu NZ,Hu YZ
Mon Feb 01 00:00:00 EST 2016
A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Tsai MH,Kuo PW,Myers CT,Li SW,Lin WC,Fu TY,Chang HY,Mefford HC,Chang YC,Tsai JW
Thu Sep 01 00:00:00 EDT 2016
A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Tsai MH,Kuo PW,Myers CT,Li SW,Lin WC,Fu TY,Chang HY,Mefford HC,Chang YC,Tsai JW
Thu Sep 01 00:00:00 EDT 2016
Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.
Biochemical and biophysical research communications
Qian G,Ren Y,Zuo Y,Yuan Y,Zhao P,Wang X,Cheng Q,Liu J,Zhang L,Guo T,Liu C,Zheng H
Fri Jun 03 00:00:00 EDT 2016
Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.
Biochemical and biophysical research communications
Qian G,Ren Y,Zuo Y,Yuan Y,Zhao P,Wang X,Cheng Q,Liu J,Zhang L,Guo T,Liu C,Zheng H
Fri Jun 03 00:00:00 EDT 2016
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Journal of biomolecular screening
Wang B,Sun J,Shi J,Guo Q,Tong X,Zhang J,Hu N,Hu Y
Fri Jul 01 00:00:00 EDT 2016
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Journal of biomolecular screening
Wang B,Sun J,Shi J,Guo Q,Tong X,Zhang J,Hu N,Hu Y
Fri Jul 01 00:00:00 EDT 2016
TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.
Oncotarget
Fritsch J,Fickers R,Klawitter J,Särchen V,Zingler P,Adam D,Janssen O,Krause E,Schütze S
Tue Nov 15 00:00:00 EST 2016
TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.
Oncotarget
Fritsch J,Fickers R,Klawitter J,Särchen V,Zingler P,Adam D,Janssen O,Krause E,Schütze S
Tue Nov 15 00:00:00 EST 2016
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
The Journal of biological chemistry
Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H
Fri Nov 25 00:00:00 EST 2016
Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon.
The Journal of biological chemistry
Li L,Qian G,Zuo Y,Yuan Y,Cheng Q,Guo T,Liu J,Liu C,Zhang L,Zheng H
Fri Nov 25 00:00:00 EST 2016
Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.
Molecular brain
Park C,Lee SA,Hong JH,Suh Y,Park SJ,Suh BK,Woo Y,Choi J,Huh JW,Kim YM,Park SK
Sat Jul 02 00:00:00 EDT 2016
Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.
Molecular brain
Park C,Lee SA,Hong JH,Suh Y,Park SJ,Suh BK,Woo Y,Choi J,Huh JW,Kim YM,Park SK
Sat Jul 02 00:00:00 EDT 2016
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 EDT 2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 EDT 2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 EDT 2015
Drosophila Dicer-2 has an RNA interference-independent function that modulates Toll immune signaling.
Science advances
Wang Z,Wu D,Liu Y,Xia X,Gong W,Qiu Y,Yang J,Zheng Y,Li J,Wang YF,Xiang Y,Hu Y,Zhou X
Thu Oct 01 00:00:00 EDT 2015
Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.
Journal of virology
Xie M,Xuan B,Shan J,Pan D,Sun Y,Shan Z,Zhang J,Yu D,Li B,Qian Z
Sun Mar 01 00:00:00 EST 2015
Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.
Journal of virology
Xie M,Xuan B,Shan J,Pan D,Sun Y,Shan Z,Zhang J,Yu D,Li B,Qian Z
Sun Mar 01 00:00:00 EST 2015
Finding Missing Proteins from the Epigenetically Manipulated Human Cell with Stringent Quality Criteria.
Journal of proteome research
Yang L,Lian X,Zhang W,Guo J,Wang Q,Li Y,Chen Y,Yin X,Yang P,Lan F,He QY,Zhang G,Wang T
Fri Sep 04 00:00:00 EDT 2015
Finding Missing Proteins from the Epigenetically Manipulated Human Cell with Stringent Quality Criteria.
Journal of proteome research
Yang L,Lian X,Zhang W,Guo J,Wang Q,Li Y,Chen Y,Yin X,Yang P,Lan F,He QY,Zhang G,Wang T
Fri Sep 04 00:00:00 EDT 2015
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates.
Neurobiology of aging
Luccarini I,Grossi C,Rigacci S,Coppi E,Pugliese AM,Pantano D,la Marca G,Ed Dami T,Berti A,Stefani M,Casamenti F
Sun Feb 01 00:00:00 EST 2015
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates.
Neurobiology of aging
Luccarini I,Grossi C,Rigacci S,Coppi E,Pugliese AM,Pantano D,la Marca G,Ed Dami T,Berti A,Stefani M,Casamenti F
Sun Feb 01 00:00:00 EST 2015
Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats.
Molecular and cellular endocrinology
Li D,Wang X,Lan X,Li Y,Liu L,Yi J,Li J,Sun Q,Wang Y,Li H,Zhong N,Holmdahl R,Lu S
Sun Feb 15 00:00:00 EST 2015
Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats.
Molecular and cellular endocrinology
Li D,Wang X,Lan X,Li Y,Liu L,Yi J,Li J,Sun Q,Wang Y,Li H,Zhong N,Holmdahl R,Lu S
Sun Feb 15 00:00:00 EST 2015
Analysis of grayscale characteristics in images of labeled microtubules from cultured cardiac myocytes.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Dang Y,Lan X,Zhang Q,Li L,Huang Y
Wed Apr 01 00:00:00 EDT 2015
Analysis of grayscale characteristics in images of labeled microtubules from cultured cardiac myocytes.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Dang Y,Lan X,Zhang Q,Li L,Huang Y
Wed Apr 01 00:00:00 EDT 2015
Cell expression patterns of CD147 in N-diethylnitrosamine/phenobarbital-induced mouse hepatocellular carcinoma.
Journal of molecular histology
Lu M,Wu J,He F,Wang XL,Li C,Chen ZN,Bian H
Sun Feb 01 00:00:00 EST 2015
Cell expression patterns of CD147 in N-diethylnitrosamine/phenobarbital-induced mouse hepatocellular carcinoma.
Journal of molecular histology
Lu M,Wu J,He F,Wang XL,Li C,Chen ZN,Bian H
Sun Feb 01 00:00:00 EST 2015
Increased stathmin expression strengthens fear conditioning in epileptic rats.
Biomedical reports
Zhang L,Feng D,Tao H,DE X,Chang Q,Hu Q
Thu Jan 01 00:00:00 EST 2015
Increased stathmin expression strengthens fear conditioning in epileptic rats.
Biomedical reports
Zhang L,Feng D,Tao H,DE X,Chang Q,Hu Q
Thu Jan 01 00:00:00 EST 2015
Modulation of amylose content by structure-based modification of OsGBSS1 activity in rice (Oryza sativa L.).
Plant biotechnology journal
Liu D,Wang W,Cai X
Mon Dec 01 00:00:00 EST 2014
Modulation of amylose content by structure-based modification of OsGBSS1 activity in rice (Oryza sativa L.).
Plant biotechnology journal
Liu D,Wang W,Cai X
Mon Dec 01 00:00:00 EST 2014
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.
The FEBS journal
Zhu M,Chen Q,Liu X,Sun Q,Zhao X,Deng R,Wang Y,Huang J,Xu M,Yan J,Yu J
Fri Aug 01 00:00:00 EDT 2014
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.
The FEBS journal
Zhu M,Chen Q,Liu X,Sun Q,Zhao X,Deng R,Wang Y,Huang J,Xu M,Yan J,Yu J
Fri Aug 01 00:00:00 EDT 2014
Axl receptor tyrosine kinase expression in breast cancer.
Journal of clinical pathology
D'Alfonso TM,Hannah J,Chen Z,Liu Y,Zhou P,Shin SJ
Fri Aug 01 00:00:00 EDT 2014
Axl receptor tyrosine kinase expression in breast cancer.
Journal of clinical pathology
D'Alfonso TM,Hannah J,Chen Z,Liu Y,Zhou P,Shin SJ
Fri Aug 01 00:00:00 EDT 2014
TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer.
Oncotarget
Li X,Liu Y,Chen W,Fang Y,Xu H,Zhu HH,Chu M,Li W,Zhuang G,Gao WQ
Wed Oct 15 00:00:00 EDT 2014
TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer.
Oncotarget
Li X,Liu Y,Chen W,Fang Y,Xu H,Zhu HH,Chu M,Li W,Zhuang G,Gao WQ
Wed Oct 15 00:00:00 EDT 2014
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Molecular and cellular biochemistry
Yunlei Z,Zhe C,Yan L,Pengcheng W,Yanbo Z,Le S,Qianjin L
Fri Feb 01 00:00:00 EST 2013
INMAP, a novel truncated version of POLR3B, represses AP-1 and p53 transcriptional activity.
Molecular and cellular biochemistry
Yunlei Z,Zhe C,Yan L,Pengcheng W,Yanbo Z,Le S,Qianjin L
Fri Feb 01 00:00:00 EST 2013
