Product References
6-Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD-1 to inhibit PD-1 signalling and enhance T cell function.
Immunology
Liu L,Lei Y,Zheng Z,Zhou X,Chen S,Zeng G,Yu L,Wang P,Chen L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2023
Regulatory T-cells and IL-5 mediate pain outcomes in a preclinical model of chronic muscle pain.
Molecular pain
Lenert ME,Szabo-Pardi TA,Burton MD
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2023
Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease.
Nature communications
Choi BJ,Park MH,Park KH,Han WH,Yoon HJ,Jung HY,Hong JY,Chowdhury MR,Kim KY,Lee J,Song IS,Pang M,Choi MK,Gulbins E,Reichel M,Kornhuber J,Hong CW,Kim C,Kim SH,Schuchman EH,Jin HK,Bae JS
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity.
Nature communications
Read KA,Jones DM,Pokhrel S,Hales EDS,Varkey A,Tuazon JA,Eisele CD,Abdouni O,Saadey A,Leonard MR,Warren RT,Powell MD,Boss JM,Hemann EA,Yount JS,Xin G,Ghoneim HE,Lio CJ,Freud AG,Collins PL,Oestreich KJ
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma.
Frontiers in pharmacology
Zhang W,Jiang X,Zou Y,Yuan L,Wang X
45-0251-82 was used in Flow Cytometry to show that the combination of pexidartinib and PD-1 antibody showed a synergy and significantly improved the anti-tumor efficacy, through pexidartinib increasing CD8T/Treg ratio by reducing TAM-derived CCL22.
Tue Mar 28 00:00:00 EDT 2023
A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy.
Theranostics
Jiang Q,Qiao B,Lin X,Cao J,Zhang N,Guo H,Liu W,Zhu L,Xie X,Wan L,Tang R,Liang B,Wang D,Wang Z,Zhou Y,Ran H,Li P
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Mar 07 00:00:00 EST 2022
Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors.
Theranostics
Cao S,Hung YW,Wang YC,Chung Y,Qi Y,Ouyang C,Zhong X,Hu W,Coblentz A,Maghami E,Sun Z,Lin HH,Ann DK
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Aug 16 00:00:00 EDT 2022
Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.
Cancer immunology research
Fedoriw A,Shi L,O'Brien S,Smitheman KN,Wang Y,Hou J,Sherk C,Rajapurkar S,Laraio J,Williams LJ,Xu C,Han G,Feng Q,Bedford MT,Wang L,Barbash O,Kruger RG,Hwu P,Mohammad HP,Peng W
45-0251-82 was used in Flow cytometry/Cell sorting to indicate that type I PRMT inhibition exhibits immunomodulatory properties and synergizes with immune checkpoint blockade to induce durable antitumor responses in a T cell-dependent manner, suggesting that type I PRMT inhibition can potentiate an antitumor immunity in refractory settings.
Fri Apr 01 00:00:00 EDT 2022
P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice.
Frontiers in immunology
Schall N,Talamini L,Wilhelm M,Jouvin-Marche E,Muller S
45-0251-82 was used in Flow cytometry/Cell sorting to suggest that P140 belongs to a new family of non-immunosuppressive immunoregulators that do not correct T and B cell abnormalities but rather contribute to the clearance of deleterious T and B cells.
Tue Jun 21 00:00:00 EDT 2022
Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant.
Frontiers in endocrinology
Martens PJ,Ellis D,Bruggeman Y,Viaene M,Laureys J,Teyton L,Mathieu C,Gysemans C
45-0251-82 was used in Flow cytometry/Cell sorting to support the use of alum as adjuvant to optimise the efficacy of antigen-specific immunotherapy in future trials.
Tue Nov 08 00:00:00 EST 2022
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
TRPM8 channel augments T-cell activation and proliferation.
Cell biology international
Acharya TK,Tiwari A,Majhi RK,Goswami C
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Exposure to Low to Moderate Doses of Ionizing Radiation Induces A Reduction of Pro-Inflammatory Ly6chigh Monocytes and a U-Curved Response of T Cells in APOE -/- Mice.
Dose-response : a publication of International Hormesis Society
Rey N,Ebrahimian T,Gloaguen C,Kereselidze D,Magneron V,Bontemps CA,Demarquay C,Olsson G,Haghdoost S,Lehoux S,Ebrahimian TG
45-0251-82 was used in Flow Cytometry to investigate the immunomodulatory response of different doses and dose-rates of irradiation in ApoE-/- mice.
Fri Jun 25 00:00:00 EDT 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy.
Journal of hematology & oncology
Kim HR,Park JS,Park JH,Yasmin F,Kim CH,Oh SK,Chung IJ,Jun CD
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Mar 17 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Cell communication and signaling : CCS
Li J,Wang S,Wang N,Zheng Y,Yang B,Wang X,Zhang J,Pan B,Wang Z
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Aug 30 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis.
BMC endocrine disorders
Wei Y,Jing J,Peng Z,Liu X,Wang X
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.
eLife
Hirano KI,Hosokawa H,Koizumi M,Endo Y,Yahata T,Ando K,Hozumi K
45-0251-82 was used in Flow Cytometry to highlight LMO2 as a crucial player in the survival and maintenance of T-lineage potential in T-cell progenitors via the regulation of the expression of Bcl11a and Tcf7.
Thu Aug 12 00:00:00 EDT 2021
Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity.
Cell reports
Wang Y,Song M,Liu M,Zhang G,Zhang X,Li MO,Ma X,Zhang JJ,Huang XY
45-0251-82 was used in Flow Cytometry to investigate the effects of fascin blockade in anti-tumor immune responses in syngeneic mouse models of various cancers.
Tue Apr 06 00:00:00 EDT 2021
Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection.
Cell
Ho JSY,Angel M,Ma Y,Sloan E,Wang G,Martinez-Romero C,Alenquer M,Roudko V,Chung L,Zheng S,Chang M,Fstkchyan Y,Clohisey S,Dinan AM,Gibbs J,Gifford R,Shen R,Gu Q,Irigoyen N,Campisi L,Huang C,Zhao N,Jones JD,van Knippenberg I,Zhu Z,Moshkina N,Meyer L,Noel J,Peralta Z,Rezelj V,Kaake R,Rosenberg B,Wang B,Wei J,Paessler S,Wise HM,Johnson J,Vannini A,Amorim MJ,Baillie JK,Miraldi ER,Benner C,Brierley I,Digard P,Łuksza M,Firth AE,Krogan N,Greenbaum BD,MacLeod MK,van Bakel H,Garcìa-Sastre A,Yewdell JW,Hutchinson E,Marazzi I
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2020
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development.
Immunity
Chopp LB,Gopalan V,Ciucci T,Ruchinskas A,Rae Z,Lagarde M,Gao Y,Li C,Bosticardo M,Pala F,Livak F,Kelly MC,Hannenhalli S,Bosselut R
45-0251-82 was used in Flow Cytometry to identify mouse and human αβ thymocyte developmental trajectories.
Tue Dec 15 00:00:00 EST 2020
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
The Journal of clinical investigation
Webb LM,Sengupta S,Edell C,Piedra-Quintero ZL,Amici SA,Miranda JN,Bevins M,Kennemer A,Laliotis G,Tsichlis PN,Guerau-de-Arellano M
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
The Journal of clinical investigation
Webb LM,Sengupta S,Edell C,Piedra-Quintero ZL,Amici SA,Miranda JN,Bevins M,Kennemer A,Laliotis G,Tsichlis PN,Guerau-de-Arellano M
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
The Journal of cell biology
Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Oct 05 00:00:00 EDT 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.
Nature communications
Buqué A,Bloy N,Perez-Lanzón M,Iribarren K,Humeau J,Pol JG,Levesque S,Mondragon L,Yamazaki T,Sato A,Aranda F,Durand S,Boissonnas A,Fucikova J,Senovilla L,Enot D,Hensler M,Kremer M,Stoll G,Hu Y,Massa C,Formenti SC,Seliger B,Elemento O,Spisek R,André F,Zitvogel L,Delaloge S,Kroemer G,Galluzzi L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2020
Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
Cell reports
Ramstead AG,Wallace JA,Lee SH,Bauer KM,Tang WW,Ekiz HA,Lane TE,Cluntun AA,Bettini ML,Round JL,Rutter J,O'Connell RM
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Mar 03 00:00:00 EST 2020
PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Cell reports
Flosbach M,Oberle SG,Scherer S,Zecha J,von Hoesslin M,Wiede F,Chennupati V,Cullen JG,List M,Pauling JK,Baumbach J,Kuster B,Tiganis T,Zehn D
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse.
Microbiome
van de Wouw M,Walsh AM,Crispie F,van Leuven L,Lyte JM,Boehme M,Clarke G,Dinan TG,Cotter PD,Cryan JF
45-0251 was used in Flow cytometry/Cell sorting to indicate that kefir can positively modulate specific aspects of the microbiota-gut-brain axis and support the broadening of the definition of psychobiotic to include kefir fermented foods.
Mon May 18 00:00:00 EDT 2020
Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse.
Microbiome
van de Wouw M,Walsh AM,Crispie F,van Leuven L,Lyte JM,Boehme M,Clarke G,Dinan TG,Cotter PD,Cryan JF
45-0251 was used in Flow cytometry/Cell sorting to indicate that kefir can positively modulate specific aspects of the microbiota-gut-brain axis and support the broadening of the definition of psychobiotic to include kefir fermented foods.
Mon May 18 00:00:00 EDT 2020
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms.
Nature communications
Watanabe M,Lu Y,Breen M,Hodes RJ
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2020
Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis.
Cell reports
Ko JH,Kim HJ,Jeong HJ,Lee HJ,Oh JY
45-0251-82 was used in Flow Cytometry to demonstrate the role of mesenchymal stem and stromal cell and macrophage cross-talk in post-injury tissue homeostasis in mice.
Tue Mar 17 00:00:00 EDT 2020
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
45-0251 was used in Flow cytometry/Cell sorting to explore the therapeutic effects and mechanisms of interleukin 10 gene-modified bone marrow-derived dendritic cells on liver fibrosis.
Tue Jun 11 00:00:00 EDT 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Jan 30 00:00:00 EST 2019
SCGN deficiency results in colitis susceptibility.
eLife
Sifuentes-Dominguez LF,Li H,Llano E,Liu Z,Singla A,Patel AS,Kathania M,Khoury A,Norris N,Rios JJ,Starokadomskyy P,Park JY,Gopal P,Liu Q,Tan S,Chan L,Ross T,Harrison S,Venuprasad K,Baker LA,Jia D,Burstein E
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Oct 30 00:00:00 EDT 2019
Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival.
Scientific reports
Uehara M,Li X,Sheikhi A,Zandi N,Walker B,Saleh B,Banouni N,Jiang L,Ordikhani F,Dai L,Yonar M,Vohra I,Kasinath V,Orgill DP,Khademhosseini A,Annabi N,Abdi R
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Apr 25 00:00:00 EDT 2019
Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.
Immunity
Shi H,Liu C,Tan H,Li Y,Nguyen TM,Dhungana Y,Guy C,Vogel P,Neale G,Rankin S,Feng Y,Peng J,Tao W,Chi H
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation.
The Journal of experimental medicine
Shin B,Kress RL,Kramer PA,Darley-Usmar VM,Bellis SL,Harrington LE
45-0251 was used in Flow cytometry/Cell sorting to indicate that the chronicity of T cell-mediated inflammation is perpetuated by specific effector CD4 T cells with stem-like properties.
Mon Jul 02 00:00:00 EDT 2018
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer's disease mice.
Journal of neuroimmunology
Kiyota T,Machhi J,Lu Y,Dyavarshetty B,Nemati M,Yokoyama I,Mosley RL,Gendelman HE
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
Immunological effects of a low-dose cytarabine, aclarubicin and granulocyte-colony stimulating factor priming regimen on a mouse leukemia model.
Oncology letters
Chen J,Yang N,Liu H,Yao H,Wang J,Yang Y,Zhang W
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Assessment of tumor growth factor-β1 neutralizing antibody in the treatment of allergic rhinitis and asthma.
Experimental and therapeutic medicine
Wei Y,Zhang Z,Wang F,Zhou S
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
JCI insight
McCall CE,Zabalawi M,Liu T,Martin A,Long DL,Buechler NL,Arts RJW,Netea M,Yoza BK,Stacpoole PW,Vachharajani V
45-0251 was used in Flow cytometry/Cell sorting to assess the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase 1 axis as a druggable mitochondrial target for promoting immunometabolic and organ homeostasis during sepsis.
Thu Aug 09 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
45-0251-82 was used in Flow cytometry/Cell sorting to describe a protocol for generating functional T cells from Hoxb5-expressing B cells in vivo.
Sat Sep 01 00:00:00 EDT 2018
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.
Cell host & microbe
Scharschmidt TC,Vasquez KS,Pauli ML,Leitner EG,Chu K,Truong HA,Lowe MM,Sanchez Rodriguez R,Ali N,Laszik ZG,Sonnenburg JL,Millar SE,Rosenblum MD
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model.
Oncology letters
Chen J,Zhang M,Zhou F,Wang J,Niu B,Zhang W
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Changes of Treg and Th17 cells as well as cytokines in children with acute bronchitis.
Experimental and therapeutic medicine
Tu Z,Xue H,Chen W,Cao L,Zhang W
45-0251 was used in Flow cytometry/Cell sorting to suggest that Treg and Th17 cells as well as their cytokines may be involved in the pathogenesis of acute bronchitis.
Sun Oct 01 00:00:00 EDT 2017
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.
Nature communications
Kim KD,Bae S,Capece T,Nedelkovska H,de Rubio RG,Smrcka AV,Jun CD,Jung W,Park B,Kim TI,Kim M
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2017
Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.
Scientific reports
Alzubi J,Pallant C,Mussolino C,Howe SJ,Thrasher AJ,Cathomen T
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Sep 29 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response.
PloS one
Kawakubo M,Demehri S,Manstein D
45-0251 was used in Flow cytometry/Cell sorting to explore the utility of ablative fractional photothermolysis in treating oncological indications, including induction of local tumour regression and inducing anti-tumour immunity.
Fri Oct 13 00:00:00 EDT 2017
Regulatory T cell frequencies and phenotypes following anti-viral vaccination.
PloS one
de Wolf ACMT,van Aalst S,Ludwig IS,Bodinham CL,Lewis DJ,van der Zee R,van Eden W,Broere F
45-0251 was used in Flow cytometry/Cell sorting to determine the impact of anti-viral vaccination on Treg homeostasis.
Fri Sep 22 00:00:00 EDT 2017
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis.
Autophagy
Lee HY,Kim J,Quan W,Lee JC,Kim MS,Kim SH,Bae JW,Hur KY,Lee MS
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Murine Butyrophilin-Like 1 and Btnl6 Form Heteromeric Complexes in Small Intestinal Epithelial Cells and Promote Proliferation of Local T Lymphocytes.
Frontiers in immunology
Lebrero-Fernández C,Bergström JH,Pelaseyed T,Bas-Forsberg A
45-0251 was used in Flow cytometry/Cell sorting to study the formation of murine Butyrophilin-like 1 and Btnl6 hetermomeric complexes in small intestinal epithelial cells and promote proliferation of local T lymphocytes.
Tue Feb 02 00:00:00 EST 2016
Generation of the First TCR Transgenic Mouse with CD4(+) T Cells Recognizing an Anti-inflammatory Regulatory T Cell-Inducing Hsp70 Peptide.
Frontiers in immunology
Jansen MA,van Herwijnen MJ,van Kooten PJ,Hoek A,van der Zee R,van Eden W,Broere F
45-0251 was used in Flow cytometry/Cell sorting to generate a novel mouse model to allow the study of primary antigen-specific T cells.
Fri Mar 25 00:00:00 EDT 2016
IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.
Mucosal immunology
Pelly VS,Kannan Y,Coomes SM,Entwistle LJ,Rückerl D,Seddon B,MacDonald AS,McKenzie A,Wilson MS
45-0251 was used in Flow cytometry/Cell sorting to highlight a previously unrecognised and important role for ILC2-derived IL-4 for TH2 differentiation in a natural TH2-dependent model of human helminthiasis.
Tue Nov 01 00:00:00 EDT 2016
Intranasal immunization with heat shock protein 60 induces CD4(+) CD25(+) GARP(+) and type 1 regulatory T cells and inhibits early atherosclerosis.
Clinical and experimental immunology
Zhong Y,Tang H,Wang X,Zeng Q,Liu Y,Zhao XI,Yu K,Shi H,Zhu R,Mao X
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development.
Journal of immunology (Baltimore, Md. : 1950)
Song Y,Kumar V,Wei HX,Qiu J,Stanley P
45-0251 was used in Flow cytometry/Cell sorting to investigate the roles for maniac fringe (MFNG) and radical fringe (RFNG) in T cell development, RFNG in B cell development, and Fringes in T and B cell activation, showing that they promote T and B cell development.
Fri Jan 01 00:00:00 EST 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model.
Molecular medicine reports
Yue Y,Li P,Song N,Li B,Li Z,Guo Y,Zhang W,Wei MQ,Gai Z,Meng H,Wang J,Qin L
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Chinese herbal medicine formula Gu-Ben-Fang-Xiao-Tang attenuates airway inflammation by modulating Th17/Treg balance in an ovalbumin-induced murine asthma model.
Experimental and therapeutic medicine
Ruan G,Tao B,Wang D,Li Y,Wu J,Yin G
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration.
Nature communications
Brinkman CC,Iwami D,Hritzo MK,Xiong Y,Ahmad S,Simon T,Hippen KL,Blazar BR,Bromberg JS
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Jun 21 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Jul 04 00:00:00 EDT 2016
Immunosuppressive effect of mesenchymal stem cell-derived exosomes on a concanavalin A-induced liver injury model.
Inflammation and regeneration
Tamura R,Uemoto S,Tabata Y
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Mar 31 00:00:00 EDT 2022
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease.
Journal of hematology & oncology
Fransolet G,Ehx G,Somja J,Delens L,Hannon M,Muller J,Dubois S,Drion P,Caers J,Humblet-Baron S,Delvenne P,Beguin Y,Conteduca G,Baron F
45-0251 was used in Flow cytometry/Cell sorting to assessed the impact of azacytidine on cGVHD in a murine model of sclerodermic cGVHD.
Mon Jul 04 00:00:00 EDT 2016
Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice.
Oncotarget
Wang Y,Tian J,Tang X,Rui K,Tian X,Ma J,Ma B,Xu H,Lu L,Wang S
45-0251 was used in Flow cytometry/Cell sorting to investigate the role of MDSCs in IBD, showing that exosomes released by granulocytic MDSCs attenuate DSS-induced colitis in mice.
Tue Mar 29 00:00:00 EDT 2016
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
Nature communications
Shi LZ,Fu T,Guan B,Chen J,Blando JM,Allison JP,Xiong L,Subudhi SK,Gao J,Sharma P
45-0251 was used in Flow cytometry/Cell sorting to study how tumour eradication can be controlled by interdependent IL-7 and IFN-γ signalling in T-cells.
Mon Aug 08 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
Nature immunology
Basu R,Whitley SK,Bhaumik S,Zindl CL,Schoeb TR,Benveniste EN,Pear WS,Hatton RD,Weaver CT
45-0251 was used in Flow cytometry/Cell sorting to assess the ability of IL-1 to override retinoic acid-mediated expression of the transcription factor Foxp3 and induce protective TH17 cell responses.
Sun Mar 01 00:00:00 EST 2015
Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells.
Immunology and cell biology
Franckaert D,Dooley J,Roos E,Floess S,Huehn J,Luche H,Fehling HJ,Liston A,Linterman MA,Schlenner SM
45-0251 was used in Flow cytometry/Cell sorting to investigate the functional requirement for CD28 during peripheral regulatory T cell post thymic selection.
Wed Apr 01 00:00:00 EDT 2015
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.
International journal of obesity (2005)
Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
ERβ and ERα Differentially Regulate NKT and Vγ4+ T-cell Activation and T-regulatory Cell Response in Coxsackievirus B3 Infected Mice.
Journal of clinical & cellular immunology
Huber S
45-0251 was used in Flow cytometry/Cell sorting to determine the relative role and mechanism of action of estrogen receptor alpha and beta in myocarditis susceptibility.
Tue Sep 29 00:00:00 EDT 2020
STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE.
Journal of neuroinflammation
McWilliams IL,Rajbhandari R,Nozell S,Benveniste E,Harrington LE
45-0251 was used in Flow cytometry/Cell sorting to establish the role of STAT4 in the regulation of cytokine production during experimental autoimmune encephalomyelitis pathogenesis.
Tue Jun 30 00:00:00 EDT 2015
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Mucosal immunology
Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M
45-0251 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.
Sat Nov 01 00:00:00 EDT 2014
CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
Journal of immunology (Baltimore, Md. : 1950)
Bignon A,Gaudin F,Hémon P,Tharinger H,Mayol K,Walzer T,Loetscher P,Peuchmaur M,Berrebi D,Balabanian K
45-0251 was used in Flow cytometry/Cell sorting to define a pivotal role for CCR4 in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of lupus-prone mice.
Sat Feb 01 00:00:00 EST 2014
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation.
Nature communications
Li Q,Zou J,Wang M,Ding X,Chepelev I,Zhou X,Zhao W,Wei G,Cui J,Zhao K,Wang HY,Wang RF
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Dec 22 00:00:00 EST 2014
Worm proteins of Schistosoma mansoni reduce the severity of experimental chronic colitis in mice by suppressing colonic proinflammatory immune responses.
PloS one
Heylen M,Ruyssers NE,De Man JG,Timmermans JP,Pelckmans PA,Moreels TG,De Winter BY
45-0251 was used in Flow cytometry/Cell sorting to investigate the therapeutic potential and immunological mechanisms of Schistosoma mansoni soluble worm protein in an adoptive T cell transfer mouse model of chronic colitis.
Tue Jun 23 00:00:00 EDT 2015
Reciprocal effects of rab7 deletion in activated and neglected T cells.
Autophagy
Roy SG,Stevens MW,So L,Edinger AL
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation.
Molecular therapy : the journal of the American Society of Gene Therapy
Gujar S,Dielschneider R,Clements D,Helson E,Shmulevitz M,Marcato P,Pan D,Pan LZ,Ahn DG,Alawadhi A,Lee PW
45-0251 was used in Flow cytometry/Cell sorting to develop a virus-based therapy that suppresses immunomodulation and targets ovarian peritoneal carcinomatosis.
Fri Feb 01 00:00:00 EST 2013
Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.
Science signaling
Cotari JW,Voisinne G,Dar OE,Karabacak V,Altan-Bonnet G
45-0251 was used in Flow cytometry/Cell sorting to investigate the effects of IL-2Rα on the sensitivity of primary mouse T lymphocytes to cytokines that signal through receptors that have the common γ chain.
Tue Mar 12 00:00:00 EDT 2013
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.
PLoS pathogens
Caignard G,Leiva-Torres GA,Leney-Greene M,Charbonneau B,Dumaine A,Fodil-Cornu N,Pyzik M,Cingolani P,Schwartzentruber J,Dupaul-Chicoine J,Guo H,Saleh M,Veillette A,Lathrop M,Blanchette M,Majewski J,Pearson A,Vidal SM
45-0251 was used in Flow cytometry/Cell sorting to identify host factors involved in HSV-1 and herpes simplex encephalitis susceptibility in an in vivo HSV-1 infectious model.
Sun Sep 01 00:00:00 EDT 2013
CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance.
American journal of physiology. Endocrinology and metabolism
Guo CA,Kogan S,Amano SU,Wang M,Dagdeviren S,Friedline RH,Aouadi M,Kim JK,Czech MP
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Flaczyk A,Duerr CU,Shourian M,Lafferty EI,Fritz JH,Qureshi ST
45-0251 was used in Flow cytometry/Cell sorting to study how allergic patterns of lung inflammation are mediated as a host response to Cryptococcus neoformans infection.
Sun Sep 01 00:00:00 EDT 2013
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Jul 31 00:00:00 EDT 2014
IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.
PloS one
Diaz-de-Durana Y,Lau J,Knee D,Filippi C,Londei M,McNamara P,Nasoff M,DiDonato M,Glynne R,Herman AE
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Mon Feb 23 00:00:00 EST 2015
Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.
PloS one
Tornack J,Seiler K,Grützkau A,Grün JR,Onodera M,Melchers F,Tsuneto M
45-0251 was used in Flow cytometry/Cell sorting to suggest that Tal-1 expression is needed to express Runx1 in the mesoderm.
Thu Aug 21 00:00:00 EDT 2014
Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Oh S,Aitken M,Simons DM,Basehoar A,Garcia V,Kropf E,Caton AJ
45-0251 was used in Flow cytometry/Cell sorting to investigate why CD4(+)CD25(+)Foxp3(+) Tregs allow organ-specific autoimmunity, showing that polyclonal Tregs suppressed Th17 cell formation and prevented arthritis development, but clonotypic Tregs did not, indicating that diverse TCR specificities are required.
Tue May 01 00:00:00 EDT 2012
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD25 monoclonal antibody (Product # 45-0251-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells.
Immunity
Park SG,Mathur R,Long M,Hosh N,Hao L,Hayden MS,Ghosh S
45-0251 was used in Flow cytometry/Cell sorting to explore the regulatory processes maintaining a tolerogenic attitude towards enteric commensal bacteria.
Wed Nov 24 00:00:00 EST 2010
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
Combination of tumor site-located CTL-associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses.
Cancer research
Tuve S,Chen BM,Liu Y,Cheng TL,Touré P,Sow PS,Feng Q,Kiviat N,Strauss R,Ni S,Li ZY,Roffler SR,Lieber A
Fri Jun 15 00:00:00 EDT 2007
