Product References
Platelet factors attenuate inflammation and rescue cognition in ageing.
Nature
Schroer AB,Ventura PB,Sucharov J,Misra R,Chui MKK,Bieri G,Horowitz AM,Smith LK,Encabo K,Tenggara I,Couthouis J,Gross JD,Chan JM,Luke A,Villeda SA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status.
Cancer immunology research
Nandre R,Verma V,Gaur P,Patil V,Yang X,Ramlaoui Z,Shobaki N,Andersen MH,Pedersen AW,Zocca MB,Mkrtichyan M,Gupta S,Khleif SN
11-0452-82 was used in Flow Cytometry to explored the possibility of generating effector cells against indoleamine-pyrrole 2,3-dioxygenase(IDO) and non-IDO tumor-derived antigens.
Tue May 03 00:00:00 EDT 2022
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
JCI insight
Zhong L,Yao L,Holdreith N,Yu W,Gui T,Miao Z,Elkaim Y,Li M,Gong Y,Pacifici M,Maity A,Busch TM,Joeng KS,Cengel K,Seale P,Tong W,Qin L
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
Cell death & disease
Sun Q,Wang Y,Ji H,Sun X,Xie S,Chen L,Li S,Zeng W,Chen R,Tang Q,Zuo J,Hou L,Hosaka K,Lu Y,Liu Y,Ye Y,Yang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2022
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress.
Scientific reports
Martín-Hernández D,Gutiérrez IL,González-Prieto M,MacDowell KS,Robledo-Montaña J,Tendilla-Beltrán H,Calleja-Rodríguez N,Bris ÁG,Ulecia-Morón C,Moreno B,Caso JR,García-Bueno B,Rodrigues-Mascarenhas S,Marín-Jiménez I,Leza JC,Menchén L
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.
The Journal of clinical investigation
Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L
11-0452 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.
Tue Jan 19 00:00:00 EST 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Lymph node formation and B cell homeostasis require IKK-α in distinct endothelial cell-derived compartments.
Proceedings of the National Academy of Sciences of the United States of America
McCorkell KA,Jayachandran N,Cully MD,Freund-Brown J,Weinkopff T,Monslow J,Hu Y,Puré E,Freedman BD,Alvarez JI,Cancro MP,May MJ
11-0452-82 was used in Flow cytometry/Cell sorting to reveal that IKK-α in distinct EC-derived compartments is uniquely required to promote B cell homeostasis and LN development, and establish that LEC-intrinsic IKK-α is absolutely essential for LN formation.
Tue Nov 30 00:00:00 EST 2021
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD.
Mucosal immunology
Richmond BW,Mansouri S,Serezani A,Novitskiy S,Blackburn JB,Du RH,Fuseini H,Gutor S,Han W,Schaff J,Vasiukov G,Xin MK,Newcomb DC,Jin L,Blackwell TS,Polosukhin VV
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system.
Computational and structural biotechnology journal
Shen Y,Jiang L,Iyer VS,Raposo B,Dubnovitsky A,Boddul SV,Kasza Z,Wermeling F
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Nov 10 00:00:00 EST 2021
Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation.
Disease models & mechanisms
Dobosz E,Lorenz G,Ribeiro A,Würf V,Wadowska M,Kotlinowski J,Schmaderer C,Potempa J,Fu M,Koziel J,Lech M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Thu Mar 18 00:00:00 EDT 2021
Defining the Mechanistic Correlates of Protection Conferred by Whole-Cell Vaccination against Pseudomonas aeruginosa Acute Murine Pneumonia.
Infection and immunity
Sen-Kilic E,Blackwood CB,Huckaby AB,Horspool AM,Weaver KL,Malkowski AC,Witt WT,Bevere JR,Damron FH,Barbier M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Jan 19 00:00:00 EST 2021
Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo.
Stem cell research
Sudo K,Yamazaki S,Wilkinson AC,Nakauchi H,Nakamura Y
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection.
Frontiers in immunology
Guo L,Li N,Yang Z,Li H,Zheng H,Yang J,Chen Y,Zhao X,Mei J,Shi H,Worthen GS,Liu L
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Tue Feb 08 00:00:00 EST 2022
Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia.
Cell death & disease
Zaccagnini G,Greco S,Longo M,Maimone B,Voellenkle C,Fuschi P,Carrara M,Creo P,Maselli D,Tirone M,Mazzone M,Gaetano C,Spinetti G,Martelli F
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
Ibrutinib does not prevent kidney fibrosis following acute and chronic injury.
Scientific reports
Belliere J,Casemayou A,Colliou E,El Hachem H,Kounde C,Piedrafita A,Feuillet G,Schanstra JP,Faguer S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Jun 07 00:00:00 EDT 2021
High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis.
PloS one
Gaurav R,Mikuls TR,Thiele GM,Nelson AJ,Niu M,Guda C,Eudy JD,Barry AE,Wyatt TA,Romberger DJ,Duryee MJ,England BR,Poole JA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Thu Jul 08 00:00:00 EDT 2021
Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4.
Life science alliance
Mendes A,Gigan JP,Rodriguez Rodrigues C,Choteau SA,Sanseau D,Barros D,Almeida C,Camosseto V,Chasson L,Paton AW,Paton JC,Argüello RJ,Lennon-Duménil AM,Gatti E,Pierre P
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Feb 01 00:00:00 EST 2021
Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans.
eLife
Hill DL,Whyte CE,Innocentin S,Lee JL,Dooley J,Wang J,James EA,Lee JC,Kwok WW,Zand MS,Liston A,Carr EJ,Linterman MA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Nov 02 00:00:00 EDT 2021
Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice.
JCI insight
Wilson CS,Stocks BT,Hoopes EM,Rhoads JP,McNew KL,Major AS,Moore DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Oct 08 00:00:00 EDT 2021
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Nature communications
Shang M,Yang H,Yang R,Chen T,Fu Y,Li Y,Fang X,Zhang K,Zhang J,Li H,Cao X,Gu J,Xiao J,Zhang Q,Liu X,Yu Q,Wang T
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Thu Oct 07 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Protein Assays and Analysis
Thu Dec 02 00:00:00 EST 2021
Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.
Science advances
Zhang YN,Paynter J,Sou C,Fourfouris T,Wang Y,Abraham C,Ngo T,Zhang Y,He L,Zhu J
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry (Frozen)
Fri Oct 22 00:00:00 EDT 2021
Inhibition of miR-29 Activity in the Myeloid Lineage Increases Response to Calcitonin and Trabecular Bone Volume in Mice.
Endocrinology
Shin B,Hrdlicka HC,Delany AM,Lee SK
11-0452-82 was used in Flow cytometry/Cell sorting to document an interrelationship between CALCR and CTSK in osteoclastic bone resorption, which is modulated by miR-29-3p.
Fri Oct 01 00:00:00 EDT 2021
Encapsulation of murine hematopoietic stem and progenitor cells in a thiol-crosslinked maleimide-functionalized gelatin hydrogel.
Acta biomaterialia
Gilchrist AE,Serrano JF,Ngo MT,Hrnjak Z,Kim S,Harley BAC
11-0452-82 was used in flow cytometry to report inclusion of a peptide crosslinker that can be cleaved via the proteolytic action of Sortase A and show that Sortase A exposure does not degrade sensitive surface marker expression patterns.
Wed Sep 01 00:00:00 EDT 2021
Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior.
Advanced functional materials
Ngo MT,Barnhouse VR,Gilchrist AE,Mahadik BP,Hunter CJ,Hensold JN,Petrikas N,Harley BAC
11-0452-82 was used in Flow cytometry/Cell sorting to report the successful development of a microfluidic device to generate hydrogels containing lateral gradients in vascular density as a means to identify angiocrine signals underlying hematopoietic stem cell culture ex vivo.
Thu Dec 16 00:00:00 EST 2021
Calciprotein Particles Induce IL-1β/α-Mediated Inflammation through NLRP3 Inflammasome-Dependent and -Independent Mechanisms.
ImmunoHorizons
Anzai F,Karasawa T,Komada T,Yamada N,Miura Y,Sampilvanjil A,Baatarjav C,Fujimura K,Matsumura T,Tago K,Kurosu H,Takeishi Y,Kuro-O M,Takahashi M
11-0452-82 was used in Flow Cytometry to provide new insights into the mechanism underlying CPP-induced inflammation and suggest that targeting both IL-1β and IL-1α is necessary to regulate the CPP-induced inflammatory response and to treat CPP-associated inflammatory disorders.
Thu Jul 29 00:00:00 EDT 2021
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Nature medicine
Koelwyn GJ,Newman AAC,Afonso MS,van Solingen C,Corr EM,Brown EJ,Albers KB,Yamaguchi N,Narke D,Schlegel M,Sharma M,Shanley LC,Barrett TJ,Rahman K,Mezzano V,Fisher EA,Park DS,Newman JD,Quail DF,Nelson ER,Caan BJ,Jones LW,Moore KJ
11-0452 was used in Flow cytometry/Cell sorting to show that myocardial infarction (MI) accelerates breast cancer outgrowth and cancer-specific mortality in mice and humans. I.
Tue Sep 01 00:00:00 EDT 2020
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Immunity
Tummers B,Mari L,Guy CS,Heckmann BL,Rodriguez DA,Rühl S,Moretti J,Crawford JC,Fitzgerald P,Kanneganti TD,Janke LJ,Pelletier S,Blander JM,Green DR
11-0452-82 was used in Flow Cytometry to suggest an in vivo role of the inflammatory RIPK1-caspase-8-FADD (FADDosome) complex and reveal a FADD-independent inflammatory role of caspase-8 that involves activation of an inflammasome.
Tue Jun 16 00:00:00 EDT 2020
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation.
Immunity
Lederer K,Castaño D,Gómez Atria D,Oguin TH,Wang S,Manzoni TB,Muramatsu H,Hogan MJ,Amanat F,Cherubin P,Lundgreen KA,Tam YK,Fan SHY,Eisenlohr LC,Maillard I,Weissman D,Bates P,Krammer F,Sempowski GD,Pardi N,Locci M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
Proceedings of the National Academy of Sciences of the United States of America
Tian M,McGovern K,Cheng HL,Waddicor P,Rieble L,Dao M,Chen Y,Kimble MT,Cantor E,Manfredonia N,Judson R,Chapdelaine-Williams A,Cain DW,Haynes BF,Alt FW
11-0452 was used in Flow cytometry/Cell sorting to develop a new approach to test a vaccine which circumvents B cell developmental blocks.
Tue Apr 07 00:00:00 EDT 2020
Ku80-Targeted pH-Sensitive Peptide-PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation.
Molecular cancer research : MCR
Kaplan AR,Pham H,Liu Y,Oyaghire S,Bahal R,Engelman DM,Glazer PM
11-0452 was used in Flow cytometry/Cell sorting to describes a novel agent, pHLIP-αKu80(γ), which combines PNA antisense and pHLIP technologies to selectively reduce the expression of the DNA repair factor KU80 in tumors and confer tumor-selective radiosensitization.
Mon Jun 01 00:00:00 EDT 2020
Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.
The Analyst
Pastrana-Otero I,Majumdar S,Gilchrist AE,Gorman BL,Harley BAC,Kraft ML
11-0452-82 was used in Flow Cytometry to show that the spectra acquired from individual living cells on functionalized PA gels attached to our custom substrates were of sufficient quality to enable accurate identification of cell phenotypes using PLS-DA models of the cell spectra.
Mon Oct 26 00:00:00 EDT 2020
Synergistic factors control kinase-phosphatase organization in B-cells engaged with supported bilayers.
Molecular biology of the cell
Núñez MF,Wisser K,Veatch SL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunocytochemistry
Thu Mar 19 00:00:00 EDT 2020
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.
Integrative biology : quantitative biosciences from nano to macro
Gilchrist AE,Harley BAC
11-0452-82 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.
Fri Jul 10 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
11-0452 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
11-0452 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota.
Pathogens (Basel, Switzerland)
Kløve S,Genger C,Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation.
Frontiers in immunology
Kreimann K,Jang MS,Rong S,Greite R,von Vietinghoff S,Schmitt R,Bräsen JH,Schiffer L,Gerstenberg J,Vijayan V,Dittrich-Breiholz O,Wang L,Karsten CM,Gwinner W,Haller H,Immenschuh S,Gueler F
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Apr 12 00:00:00 EDT 2021
Overcoming Immunological Challenges to Helper-Dependent Adenoviral Vector-Mediated Long-Term CFTR Expression in Mouse Airways.
Genes
Cao H,Duan R,Hu J
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection.
Frontiers in immunology
Larson SR,Bortell N,Illies A,Crisler WJ,Matsuda JL,Lenz LL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity.
Frontiers in immunology
Myers DR,Abram CL,Wildes D,Belwafa A,Welsh AMN,Schulze CJ,Choy TJ,Nguyen T,Omaque N,Hu Y,Singh M,Hansen R,Goldsmith MA,Quintana E,Smith JAM,Lowell CA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells.
International journal of molecular sciences
Natsume C,Aoki N,Aoyama T,Senda K,Matsui M,Ikegami A,Tanaka K,Azuma YT,Fujita T
11-0452-82 was used in Immunohistochemistry to demonstrate that FX exerts anti-inflammatory effects on keratinocytes and ameliorates AD symptoms by regulating ILCreg to normalize immune responses in an atopic dermatitis model.
Sun Mar 22 00:00:00 EDT 2020
Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells.
International journal of molecular sciences
Natsume C,Aoki N,Aoyama T,Senda K,Matsui M,Ikegami A,Tanaka K,Azuma YT,Fujita T
11-0452-82 was used in Immunohistochemistry to demonstrate that FX exerts anti-inflammatory effects on keratinocytes and ameliorates AD symptoms by regulating ILCreg to normalize immune responses in an atopic dermatitis model.
Sun Mar 22 00:00:00 EDT 2020
The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Tue Sep 29 00:00:00 EDT 2020
MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner.
Cell reports
Cordeiro B,Jeon P,Boukhaled GM,Corrado M,Lapohos O,Roy DG,Williams K,Jones RG,Gruenheid S,Sagan SM,Krawczyk CM
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that miR-9 facilitates the transition of DCs from steady state to mature state by regulating the expression of several negative regulators of DC function in a cell-type-specific manner.
Tue May 05 00:00:00 EDT 2020
Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.
Cell reports
Miyamoto R,Okuda H,Kanai A,Takahashi S,Kawamura T,Matsui H,Kitamura T,Kitabayashi I,Inaba T,Yokoyama A
11-0452-82 was used in Flow Cytometry to reveal that activation of unmethylated CpG-rich promoters mediated by MLL is the central mechanism of oncogenic self-renewal in MOZ-rearranged leukemia.
Tue Sep 29 00:00:00 EDT 2020
PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice.
Stem cell research & therapy
Deng Q,Huang S,Wen J,Jiao Y,Su X,Shi G,Huang J
11-0452-82 was used in Flow cytometry/Cell sorting to investigate the role of Pluronic F-127 (PF-127) hydrogel plus antioxidant sodium ascorbyl phosphate (SAP) in enhancing Wharton's jelly mesenchymal stem cell (WJMSC)-mediated effectiveness on full-thickness skin wound healing in mice.
Fri Apr 03 00:00:00 EDT 2020
Cep55 overexpression promotes genomic instability and tumorigenesis in mice.
Communications biology
Sinha D,Nag P,Nanayakkara D,Duijf PHG,Burgess A,Raninga P,Smits VAJ,Bain AL,Subramanian G,Wall M,Finnie JW,Kalimutho M,Khanna KK
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Wed Oct 21 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model.
International journal of molecular sciences
Aung KT,Akiyama K,Kunitomo M,Mun AY,Tosa I,Nguyen HTT,Zhang J,Kohno T,Ono M,Hara ES,Kuboki T
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunocytochemistry
Fri Oct 30 00:00:00 EDT 2020
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.
Cell reports
Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ
11-0452 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.
Tue Jan 07 00:00:00 EST 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Jul 06 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
11-0452-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.
eLife
Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L
11-0452 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.
Tue Apr 14 00:00:00 EDT 2020
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
11-0452 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
GM-CSF Promotes Antitumor Immunity by Inducing Th9 Cell Responses.
Cancer immunology research
Kim IK,Koh CH,Jeon I,Shin KS,Kang TS,Bae EA,Seo H,Ko HJ,Kim BS,Chung Y,Kang CY
11-0452-82 was used in Flow Cytometry to demonstrate that GM-CSF potentiates the efficacy of cancer vaccines through IL9-producing Th (Th9) cells.
Fri Mar 01 00:00:00 EST 2019
Memory CD4+ T cells enhance B-cell responses to drifting influenza immunization.
European journal of immunology
Gage E,Van Hoeven N,Dubois Cauwelaert N,Larsen SE,Erasmus J,Orr MT,Coler RN
11-0452-82 was used in Flow Cytometry to show that MHC Class II haplotype and T-cell reactivity influences subsequent hemagglutination inhibitory antibody responses.
Fri Feb 01 00:00:00 EST 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue May 14 00:00:00 EDT 2019
The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.
Cell reports
Adane B,Ye H,Khan N,Pei S,Minhajuddin M,Stevens BM,Jones CL,D'Alessandro A,Reisz JA,Zaberezhnyy V,Gasparetto M,Ho TC,Kelly KK,Myers JR,Ashton JM,Siegenthaler J,Kume T,Campbell EL,Pollyea DA,Becker MW,Jordan CT
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Apr 02 00:00:00 EDT 2019
Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Nature communications
Broderick L,Yost S,Li D,McGeough MD,Booshehri LM,Guaderrama M,Brydges SD,Kucharova K,Patel NC,Harr M,Hakonarson H,Zackai E,Cowell IG,Austin CA,Hügle B,Gebauer C,Zhang J,Xu X,Wang J,Croker BA,Frazer KA,Putnam CD,Hoffman HM
11-0452-82 was used in Flow Cytometry to identify mutations in type II topoisomerase as a driver of defective proliferation and survival of B2 cells, leading to a B cell immunodeficiency.
Tue Aug 13 00:00:00 EDT 2019
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Cell reports
Goldstein JM,Tabebordbar M,Zhu K,Wang LD,Messemer KA,Peacker B,Ashrafi Kakhki S,Gonzalez-Celeiro M,Shwartz Y,Cheng JKW,Xiao R,Barungi T,Albright C,Hsu YC,Vandenberghe LH,Wagers AJ
11-0452 was used in Flow cytometry/Cell sorting to demonstrate in vivo transduction of endogenous tissue stem cells in the muscle, blood, and skin by systemic or local administration of adeno-associated viruses (AAVs) encoding genome-modifying enzymes.
Tue Apr 23 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
11-0452 was used in Flow cytometry/Cell sorting to provide genetic evidence supporting that NKG2A and the inhibitory members of Ly49 family receptors synergize to regulate NK cell education.
Fri Nov 01 00:00:00 EDT 2019
Trained immunity modulates inflammation-induced fibrosis.
Nature communications
Jeljeli M,Riccio LGC,Doridot L,Chêne C,Nicco C,Chouzenoux S,Deletang Q,Allanore Y,Kavian N,Batteux F
11-0452 was used in Flow cytometry/Cell sorting to show the effect of BCG or low-dose LPS stimulation on macrophage phenotype, cytokine production, chromatin and metabolic modifications.
Wed Dec 11 00:00:00 EST 2019
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
11-0452 was used in Flow cytometry/Cell sorting to confirm that one-step zygotic injections of CRISPR/Cas gene editing complexes provide a quick and powerful tool to generate gene-modified mouse models.
Mon Dec 09 00:00:00 EST 2019
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
Nature medicine
Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Immunity
Emgård J,Kammoun H,García-Cassani B,Chesné J,Parigi SM,Jacob JM,Cheng HW,Evren E,Das S,Czarnewski P,Sleiers N,Melo-Gonzalez F,Kvedaraite E,Svensson M,Scandella E,Hepworth MR,Huber S,Ludewig B,Peduto L,Villablanca EJ,Veiga-Fernandes H,Pereira JP,Flavell RA,Willinger T
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Tue Jan 16 00:00:00 EST 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
11-0452 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
11-0452-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.
Cell stem cell
Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J
11-0452-82 was used in Immunohistochemistry (PFA fixed) to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.
Thu Mar 01 00:00:00 EST 2018
IL1RAP potentiates multiple oncogenic signaling pathways in AML.
The Journal of experimental medicine
Mitchell K,Barreyro L,Todorova TI,Taylor SJ,Antony-Debré I,Narayanagari SR,Carvajal LA,Leite J,Piperdi Z,Pendurti G,Mantzaris I,Paietta E,Verma A,Gritsman K,Steidl U
11-0452 was used in Flow cytometry/Cell sorting to show that targeting of interleukin-1 receptor accessory protein via RNA interference, genetic deletion, or antibodies inhibits acute myeloid leukaemia pathogenesis in vitro and in vivo.
Mon Jun 04 00:00:00 EDT 2018
Microbial symbionts regulate the primary Ig repertoire.
The Journal of experimental medicine
Chen Y,Chaudhary N,Yang N,Granato A,Turner JA,Howard SL,Devereaux C,Zuo T,Shrestha A,Goel RR,Neuberg D,Wesemann DR
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Mon May 07 00:00:00 EDT 2018
Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22.
Cell death and differentiation
Hou Q,Ye L,Liu H,Huang L,Yang Q,Turner JR,Yu Q
11-0452 was used in Flow cytometry/Cell sorting to explore the protective effect of Lactobacillus reuteri D8 on integrity of intestinal mucosa.
Sat Sep 01 00:00:00 EDT 2018
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
Arteriosclerosis, thrombosis, and vascular biology
Karasawa T,Kawashima A,Usui-Kawanishi F,Watanabe S,Kimura H,Kamata R,Shirasuna K,Koyama Y,Sato-Tomita A,Matsuzaka T,Tomoda H,Park SY,Shibayama N,Shimano H,Kasahara T,Takahashi M
Sun Apr 01 00:00:00 EDT 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts.
Frontiers in immunology
Baur J,Otto C,Steger U,Klein-Hessling S,Muhammad K,Pusch T,Murti K,Wismer R,Germer CT,Klein I,Müller N,Serfling E,Avots A
11-0452 was used in Flow cytometry/Cell sorting to show that the activity of nuclear factors of activated T cells-c1 supports the acute rejection of heterotopic heart allografts.
Wed Nov 20 00:00:00 EST 2019
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections.
Journal of virology
Sin SH,Eason AB,Bigi R,Kim Y,Kang S,Tan K,Seltzer TA,Venkataramanan R,An H,Dittmer DP
11-0452 was used in Flow cytometry/Cell sorting to explore the potential of using kaposi's sarcoma-associated herpesvirus(KSHV)for in vivo B cell reprogramming.
Mon Oct 01 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43.
Experimental and therapeutic medicine
Li Z,Zhang S,Cao L,Li W,Ye YC,Shi ZX,Wang ZR,Sun LX,Wang JW,Jia LT,Wang W
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis.
European journal of microbiology & immunology
Escher U,Giladi E,Dunay IR,Bereswill S,Gozes I,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry (Paraffin)
Mon Jun 25 00:00:00 EDT 2018
Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.
Frontiers in immunology
Perez-Chacon G,Adrados M,Vallejo-Cremades MT,Lefebvre S,Reed JC,Zapata JM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
Macrophages orchestrate breast cancer early dissemination and metastasis.
Nature communications
Linde N,Casanova-Acebes M,Sosa MS,Mortha A,Rahman A,Farias E,Harper K,Tardio E,Reyes Torres I,Jones J,Condeelis J,Merad M,Aguirre-Ghiso JA
11-0452 was used in Flow cytometry/Cell sorting to show that, in pre-malignant lesions, CCL2 produced by cancer cells and myeloid cells attracts CD206+/Tie2+macrophages and induces Wnt-1 upregulation that in turn downregulates E-cadherin junctions in the HER2+early cancer cells.
Tue Jan 02 00:00:00 EST 2018
Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry.
Scientific reports
Beesetty P,Wieczerzak KB,Gibson JN,Kaitsuka T,Luu CT,Matsushita M,Kozak JA
11-0452 was used in Flow cytometry/Cell sorting to study the role of TRPM7 channel kinase as a novel modulator of blastogenesis, proliferation and store-operated calcium entry.
Wed Feb 14 00:00:00 EST 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
11-0452 was used in Flow cytometry/Cell sorting to study the role of type 2 innate lymphoid cells in enhancing anti-cancer immunity and controlling metastasis.
Tue Feb 13 00:00:00 EST 2018
Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.
Cell reports
Omata Y,Frech M,Primbs T,Lucas S,Andreev D,Scholtysek C,Sarter K,Kindermann M,Yeremenko N,Baeten DL,Andreas N,Kamradt T,Bozec A,Ramming A,Krönke G,Wirtz S,Schett G,Zaiss MM
11-0452 was used in Flow cytometry/Cell sorting to elucidate the role of group 2 innate lymphoid cells in arthritis.
Tue Jul 03 00:00:00 EDT 2018
A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.
PloS one
Stefanski HE,Jonart L,Goren E,Mulé JJ,Blazar BR
11-0452 was used in Immunohistochemistry to provide the foundation for future trials of DC/CCL21 vaccination in patients receiving pre-transplant conditioning regimens.
Fri Jul 13 00:00:00 EDT 2018
Orally administered heat-killed Lactobacillus paracasei MCC1849 enhances antigen-specific IgA secretion and induces follicular helper T cells in mice.
PloS one
Arai S,Iwabuchi N,Takahashi S,Xiao JZ,Abe F,Hachimura S
11-0452 was used in Flow cytometry/Cell sorting to investigate the effects of orally administered heat-killed MCC1849 on IgA production in the intestine and on Tfh cell induction in vivo.
Wed Jan 02 00:00:00 EST 2019
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
11-0452 was used in Flow cytometry/Cell sorting to describe the function of ILC2 in the regulation of lung inflammation by protecting lung endothelial cell from pyroptosis.
Tue Mar 06 00:00:00 EST 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
11-0452 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 EDT 2019
In utero nanoparticle delivery for site-specific genome editing.
Nature communications
Ricciardi AS,Bahal R,Farrelly JS,Quijano E,Bianchi AH,Luks VL,Putman R,López-Giráldez F,Coşkun S,Song E,Liu Y,Hsieh WC,Ly DH,Stitelman DH,Glazer PM,Saltzman WM
Tue Jun 26 00:00:00 EDT 2018
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.
Nature communications
Brosseau JP,Liao CP,Wang Y,Ramani V,Vandergriff T,Lee M,Patel A,Ariizumi K,Le LQ
11-0452 was used in Flow cytometry/Cell sorting to study the role of the neurofibromatosis type 1 tumour suppressor gene in de novo tumorigenesis and malignant transformation.
Tue Nov 27 00:00:00 EST 2018
ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response.
Scientific reports
Rodríguez-Baena FJ,Redondo-García S,Peris-Torres C,Martino-Echarri E,Fernández-Rodríguez R,Plaza-Calonge MDC,Anderson P,Rodríguez-Manzaneque JC
11-0452 was used in Flow cytometry/Cell sorting to confirm a pro-inflammatory landscape in the absence of ADAMTS1, correlating with tumour blockade, supporting its novel role as a modulator of the immune cell response.
Thu Aug 30 00:00:00 EDT 2018
Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.
JCI insight
Arifuzzaman M,Ang WXG,Choi HW,Nilles ML,St John AL,Abraham SN
11-0452-82 was used in Flow Cytometry to examine how Yersinia pestis converts immunocytes recruited by host to contain the pathogen into vehicles for bacterial dispersal and the role of immune cell death in this context.
Thu Sep 20 00:00:00 EDT 2018
Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide.
Neoplasia (New York, N.Y.)
Pittala S,Krelin Y,Shoshan-Barmatz V
11-0452 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to show that the voltage-dependent anion channel-based peptide R-Tf-D-LP4 has multiple effects on liver cancer cells.
Fri Jun 01 00:00:00 EDT 2018
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
Cell
Isoda T,Moore AJ,He Z,Chandra V,Aida M,Denholtz M,Piet van Hamburg J,Fisch KM,Chang AN,Fahl SP,Wiest DL,Murre C
Thu Sep 21 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Apr 03 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Mon Apr 03 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
11-0452 was used in Flow cytometry/Cell sorting to define a fundamental function of Egr2 and Egr3, operating as a checkpoint controlling the transition between clonal expansion and differentiation of effector T cells.
Mon Jun 05 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
11-0452 was used in Flow cytometry/Cell sorting to propose that Samd14-Enh and an ensemble of anemia-responsive enhancers are essential for erythrocyte regeneration in stress erythropoiesis.
Mon Aug 07 00:00:00 EDT 2017
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.
PLoS medicine
Xu J,Guardado J,Hoffman R,Xu H,Namas R,Vodovotz Y,Xu L,Ramadan M,Brown J,Turnquist HR,Billiar TR
11-0452 was used in Flow cytometry/Cell sorting to suggest that IL33 may initiate early detrimental type 2 immune responses after trauma through ILC2 regulation of neutrophil IL5 production.
Sat Jul 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
11-0452 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation.
Journal of immunology (Baltimore, Md. : 1950)
Russell Knode LM,Naradikian MS,Myles A,Scholz JL,Hao Y,Liu D,Ford ML,Tobias JW,Cancro MP,Gearhart PJ
11-0452 was used in Flow cytometry/Cell sorting to show that quiescent ABCs are Ag-experienced cells that accumulate during T cell-dependent responses to diverse Ags during the life of an individual.
Wed Mar 01 00:00:00 EST 2017
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications
Béguelin W,Rivas MA,Calvo Fernández MT,Teater M,Purwada A,Redmond D,Shen H,Challman MF,Elemento O,Singh A,Melnick AM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2017
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.
Nature communications
Ottina E,Peperzak V,Schoeler K,Carrington E,Sgonc R,Pellegrini M,Preston S,Herold MJ,Strasser A,Villunger A
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Oct 18 00:00:00 EDT 2017
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.
Cell reports
Mehta C,Johnson KD,Gao X,Ong IM,Katsumura KR,McIver SC,Ranheim EA,Bresnick EH
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
PloS one
Komegae EN,Souza TA,Grund LZ,Lima C,Lopes-Ferreira M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
11-0452-82 was used in Flow Cytometry to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Sat Jan 09 00:00:00 EST 2021
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis.
Scientific reports
Peshkova IO,Fatkhullina AR,Mikulski Z,Ley K,Koltsova EK
11-0452 was used in Flow cytometry/Cell sorting to study the role of IL-27R in controlling myeloid cell accumulation and activation in atherosclerosis.
Tue May 23 00:00:00 EDT 2017
Ceramide synthesis regulates T cell activity and GVHD development.
JCI insight
Sofi MH,Heinrichs J,Dany M,Nguyen H,Dai M,Bastian D,Schutt S,Wu Y,Daenthanasanmak A,Gencer S,Zivkovic A,Szulc Z,Stark H,Liu C,Chang YJ,Ogretmen B,Yu XZ
11-0452 was used in Flow cytometry/Cell sorting to define the involvement of ceramides in the T-cell response to alloantigens present after allogeneic haematopoietic cell transplantation.
Thu May 18 00:00:00 EDT 2017
Antibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo.
Scientific reports
Liew PX,Kim JH,Lee WY,Kubes P
11-0452 was used in Flow cytometry/Cell sorting to investigate a novel antibody-dependent cell death pathway.
Tue Sep 05 00:00:00 EDT 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
11-0452 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.
The Journal of clinical investigation
Nguyen HD,Chatterjee S,Haarberg KM,Wu Y,Bastian D,Heinrichs J,Fu J,Daenthanasanmak A,Schutt S,Shrestha S,Liu C,Wang H,Chi H,Mehrotra S,Yu XZ
11-0452 was used in Flow cytometry/Cell sorting to study the metabolic reprogramming of donor T cells following allogeneic haematopoietic cell transplantation.
Fri Apr 01 00:00:00 EDT 2016
DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.
The Journal of experimental medicine
Maul RW,MacCarthy T,Frank EG,Donigan KA,McLenigan MP,Yang W,Saribasak H,Huston DE,Lange SS,Woodgate R,Gearhart PJ
11-0452 was used in Flow cytometry/Cell sorting to analyse different mutations in DNA polymerase Ι in two strains of mice with deficiencies in the enzyme.
Mon Aug 22 00:00:00 EDT 2016
CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.
Frontiers in immunology
Schmitt ME,Sitte S,Voehringer D
11-0452 was used in Flow cytometry/Cell sorting to determine whether memory-like T cells can efficiently respond to foreign antigen and participate in antiviral immunity.
Wed Nov 20 00:00:00 EST 2019
Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.
PLoS pathogens
Frenkel D,Zhang F,Guirnalda P,Haynes C,Bockstal V,Radwanska M,Magez S,Black SJ
11-0452 was used in Flow cytometry/Cell sorting to investigate the mechanism by which natural killer cells in Trypanosoma brucei infected mice kill B cells, suppress humoral immunity and induce early mortality.
Fri Jul 01 00:00:00 EDT 2016
Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.
International journal of cancer
Allaire JM,Roy SA,Ouellet C,Lemieux É,Jones C,Paquet M,Boudreau F,Perreault N
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Flt3 Ligand Regulates the Development of Innate Lymphoid Cells in Fetal and Adult Mice.
Journal of immunology (Baltimore, Md. : 1950)
Baerenwaldt A,von Burg N,Kreuzaler M,Sitte S,Horvath E,Peter A,Voehringer D,Rolink AG,Finke D
11-0452 was used in Flow cytometry/Cell sorting to investigate the role of the Flt3 ligand in the development and regulation of innate lymphoid cells in fetal and adult mice.
Tue Mar 15 00:00:00 EDT 2016
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Hilpert C,Sitte S,Matthies A,Voehringer D
11-0452 was used in Flow cytometry/Cell sorting to study the role of dendritic cells as antigen presenting cells and a source of type I interferons in acute lymphocytic choriomeningitis virus infection.
Sat Oct 01 00:00:00 EDT 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
11-0452 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Nature communications
Jiang X,Hu C,Arnovitz S,Bugno J,Yu M,Zuo Z,Chen P,Huang H,Ulrich B,Gurbuxani S,Weng H,Strong J,Wang Y,Li Y,Salat J,Li S,Elkahloun AG,Yang Y,Neilly MB,Larson RA,Le Beau MM,Herold T,Bohlander SK,Liu PP,Zhang J,Li Z,He C,Jin J,Hong S,Chen J
11-0452 was used in Flow cytometry/Cell sorting to investigate the anti-tumourigenic role of miR-22, showing that it has an anti-tumour role in acute myeloid leukaemia.
Tue Apr 26 00:00:00 EDT 2016
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis.
PloS one
Braun J,Meixner A,Brachner A,Foisner R
11-0452 was used in Flow cytometry/Cell sorting to test whether ANKLE1 may contribute to Holliday junction resolution during DNA repair in mice.
Fri Aug 12 00:00:00 EDT 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
11-0452 was used in Flow cytometry/Cell sorting to indicate a close link between NFATc1 and IL-10 expression in B cells, suggesting that NFATc1 may be a potential target to treat human psoriasis.
Wed May 25 00:00:00 EDT 2016
Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae.
PLoS neglected tropical diseases
Pionnier N,Brotin E,Karadjian G,Hemon P,Gaudin-Nomé F,Vallarino-Lhermitte N,Nieguitsila A,Fercoq F,Aknin ML,Marin-Esteban V,Chollet-Martin S,Schlecht-Louf G,Bachelerie F,Martin C
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that neutrophils contribute to early anti-filarial host responses via oxidative burst, degranulation and NETosis.
Fri Apr 01 00:00:00 EDT 2016
Splenic Leukocytes Traffic to the Thyroid and Produce a Novel TSHβ Isoform during Acute Listeria monocytogenes Infection in Mice.
PloS one
Montufar-Solis D,Klein JR
11-0452 was used in Flow cytometry/Cell sorting to show that within three days of systemic infection of mice with Listeria monocytogenes, splenic leukocytes synthesized elevated levels of TSHβv.
Mon Jul 11 00:00:00 EDT 2016
PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.
Nature communications
Ola R,Dubrac A,Han J,Zhang F,Fang JS,Larrivée B,Lee M,Urarte AA,Kraehling JR,Genet G,Hirschi KK,Sessa WC,Canals FV,Graupera M,Yan M,Young LH,Oh PS,Eichmann A
11-0452 was used in Flow cytometry/Cell sorting to study how Alk1 deletion leads to increased endothelial PI3K pathway activation that may be a novel target for the treatment of vascular lesions in HHT2.
Tue Nov 29 00:00:00 EST 2016
Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells.
BMC immunology
Kasamatsu J,Deng M,Azuma M,Funami K,Shime H,Oshiumi H,Matsumoto M,Kasahara M,Seya T
11-0452 was used in Flow cytometry/Cell sorting to suggest that a set of triggering receptors expressed on myeloid cells are up-regulated in response to viral RNA.
Tue May 03 00:00:00 EDT 2016
GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.
Nature biotechnology
Agudo J,Ruzo A,Park ES,Sweeney R,Kana V,Wu M,Zhao Y,Egli D,Merad M,Brown BD
11-0452 was used in Flow cytometry/Cell sorting to generate and use GFP-specific CD8 T cells to investigate less understood cell types and their interactions with the immune system.
Tue Dec 01 00:00:00 EST 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that injected mesoporous silica rods assemble in vivo to form structures providing a 3D cellular microenvironment for host immune cells.
Thu Jan 01 00:00:00 EST 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
The Journal of experimental medicine
Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC
11-0452 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.
Mon Jun 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
11-0452 was used in Flow cytometry/Cell sorting to illustrate a paradigm in which cis-elements in a locus differentially control stem and progenitor cell transitions.
Tue Sep 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Tue Dec 29 00:00:00 EST 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.
Immunity & ageing : I & A
Matsuda T,Yanase S,Takaoka A,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Mon Mar 02 00:00:00 EST 2015
The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo.
PLoS biology
Turqueti-Neves A,Otte M,Schwartz C,Schmitt ME,Lindner C,Pabst O,Yu P,Voehringer D
11-0452 was used in Flow cytometry/Cell sorting to explore the relationship between repertoires of IgE and IgG1 in vivo.
Tue May 24 00:00:00 EDT 2016
DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers.
Journal of virology
Gupta S,Clark ES,Termini JM,Boucher J,Kanagavelu S,LeBranche CC,Abraham S,Montefiori DC,Khan WN,Stone GW
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that a DNA vaccine encoding soluble adjuvant multitrimers, IL-12p70, and membrane-bound HIV-1 Env gp140 induces HIV-1 neutralising antibodies in mice.
Wed Apr 01 00:00:00 EDT 2015
DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers.
Journal of virology
Gupta S,Clark ES,Termini JM,Boucher J,Kanagavelu S,LeBranche CC,Abraham S,Montefiori DC,Khan WN,Stone GW
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that a DNA vaccine encoding soluble adjuvant multitrimers, IL-12p70, and membrane-bound HIV-1 Env gp140 induces HIV-1 neutralising antibodies in mice.
Wed Apr 01 00:00:00 EDT 2015
ATAD5 deficiency decreases B cell division and Igh recombination.
Journal of immunology (Baltimore, Md. : 1950)
Zanotti KJ,Maul RW,Castiblanco DP,Yang W,Choi YJ,Fox JT,Myung K,Saribasak H,Gearhart PJ
11-0452 was used in Flow cytometry/Cell sorting to examine the effects of decreased B cell proliferation on Ab diversity.
Thu Jan 01 00:00:00 EST 2015
Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that Spred1, a negative regulator of the Ras-ERK pathway, plays an important role in the proliferation and apoptosis of ILC2s and in cytokine secretion from ILC2s.
Sat Aug 01 00:00:00 EDT 2015
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Schaffert SA,Loh C,Wang S,Arnold CP,Axtell RC,Newell EW,Nolan G,Ansel KM,Davis MM,Steinman L,Chen CZ
11-0452 was used in Flow cytometry/Cell sorting to explore the physiological control of tolerance by manipulating microRNA gene products.
Sat Aug 15 00:00:00 EDT 2015
Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.
Carcinogenesis
Dabydeen SA,Kang K,Díaz-Cruz ES,Alamri A,Axelrod ML,Bouker KB,Al-Kharboosh R,Clarke R,Hennighausen L,Furth PA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Thu Jan 01 00:00:00 EST 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2015
The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity.
Infection and immunity
Shourian M,Flaczyk A,Angers I,Mindt BC,Fritz JH,Qureshi ST
11-0452 was used in Flow cytometry/Cell sorting to show that Cryptococcus neoformans infected lungs showed a significantly higher number of neutrophils, exudate macrophages, CD11b(+) dendritic cells, and CD4(+) cells in B6.CBA-Cnes2 than in C57BL/6 mice.
Tue Dec 01 00:00:00 EST 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
11-0452-82 was used in Flow Cytometry to suggest that the recently described nuclear variant of BMP2 is necessary for efficient secondary immune responses.
Mon Aug 01 00:00:00 EDT 2016
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.
Nature communications
Kanno A,Tanimura N,Ishizaki M,Ohko K,Motoi Y,Onji M,Fukui R,Shimozato T,Yamamoto K,Shibata T,Sano S,Sugahara-Tobinai A,Takai T,Ohto U,Shimizu T,Saitoh S,Miyake K
11-0452 was used in Flow cytometry/Cell sorting to show that Toll-like receptor 7 (TLR7) is present on the cell surface of immune cells and that TLR7 responses can be inhibited by an anti-TLR7 antibody.
Wed Feb 04 00:00:00 EST 2015
Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss.
Nature communications
Ofotokun I,Titanji K,Vikulina T,Roser-Page S,Yamaguchi M,Zayzafoon M,Williams IR,Weitzmann MN
11-0452 was used in Flow cytometry/Cell sorting to suggest T-cell repopulation and/or immune reconstitution as putative mechanisms for bone loss following ART initiation.
Tue Sep 22 00:00:00 EDT 2015
CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow.
Scientific reports
Fujimura N,Xu B,Dalman J,Deng H,Aoyama K,Dalman RL
11-0452 was used in Flow cytometry/Cell sorting to demonstrate the central role CCR2 plays in mediating leukocyte mobilization from the bone marrow and suggest a role for CCR2 inhibition in managing monocytes/macrophages-mediated chronic inflammatory conditions.
Fri Jul 24 00:00:00 EDT 2015
CLEC-2 is required for development and maintenance of lymph nodes.
Blood
Bénézech C,Nayar S,Finney BA,Withers DR,Lowe K,Desanti GE,Marriott CL,Watson SP,Caamaño JH,Buckley CD,Barone F
11-0452 was used in Flow cytometry/Cell sorting to investigate the role that CLEC-2 plays in the development and maintenance of lymph nodes.
Thu May 15 00:00:00 EDT 2014
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells.
The EMBO journal
Jurkin J,Henkel T,Nielsen AF,Minnich M,Popow J,Kaufmann T,Heindl K,Hoffmann T,Busslinger M,Martinez J
11-0452 was used in Flow cytometry/Cell sorting to investigate the mammalian ligase required for cleavage of XBP1, showing that tRNA ligase complex mediates splicing of XBP1 mRNA.
Wed Dec 17 00:00:00 EST 2014
Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor.
Stem cells (Dayton, Ohio)
Povinelli BJ,Nemeth MJ
11-0452 was used in Flow cytometry/Cell sorting to study whether Ryk protein regulates the response of haematopoietic stem cells to Wnt5a.
Wed Jan 01 00:00:00 EST 2014
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response.
Journal of immunology (Baltimore, Md. : 1950)
Park KS,Bayles I,Szlachta-McGinn A,Paul J,Boiko J,Santos P,Liu J,Wang Z,Borghesi L,Milcarek C
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Sat Nov 01 00:00:00 EDT 2014
IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner.
Journal of immunology (Baltimore, Md. : 1950)
Alves BN,Tsui R,Almaden J,Shokhirev MN,Davis-Turak J,Fujimoto J,Birnbaum H,Ponomarenko J,Hoffmann A
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Stoolman JS,Duncker PC,Huber AK,Segal BM
11-0452 was used in Flow cytometry/Cell sorting to investigate the role of CXCL2 in atypical EAE, showing that site-specific chemokine expression regulates CNS inflammation and determines clinical phenotype.
Tue Jul 15 00:00:00 EDT 2014
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J
11-0452 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.
Tue Apr 01 00:00:00 EDT 2014
Antigen delivery to CD11c+CD8- dendritic cells induces protective immune responses against experimental melanoma in mice in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Neubert K,Lehmann CH,Heger L,Baranska A,Staedtler AM,Buchholz VR,Yamazaki S,Heidkamp GF,Eissing N,Zebroski H,Nussenzweig MC,Nimmerjahn F,Dudziak D
11-0452 was used in Flow cytometry/Cell sorting to assess the anti-tumour efficacy of a highly selective immunisation-based therapy.
Sun Jun 15 00:00:00 EDT 2014
Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells.
Molecular and cellular biology
Kahlfuß S,Simma N,Mankiewicz J,Bose T,Lowinus T,Klein-Hessling S,Sprengel R,Schraven B,Heine M,Bommhardt U
11-0452 was used in Flow cytometry/Cell sorting to investigate the effect of NMDAR antagonists on T-cell function, showing that antagonists cause immunosuppression via inhibition of Kv1.3 and KCa3.1 channels in T-cells.
Sat Mar 01 00:00:00 EST 2014
Rhof promotes murine marginal zone B cell development.
Nagoya journal of medical science
Kishimoto M,Matsuda T,Yanase S,Katsumi A,Suzuki N,Ikejiri M,Takagi A,Ikawa M,Kojima T,Kunishima S,Kiyoi H,Naoe T,Matsushita T,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Mon Dec 22 00:00:00 EST 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Mon Dec 22 00:00:00 EST 2014
Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis.
Journal of inflammation research
Yoo J,Manicone AM,McGuire JK,Wang Y,Parks WC
11-0452 was used in Flow cytometry/Cell sorting to reveal a mouse model of atopic dermatitis that reveals novel insights into the pathogenesis of this complex disease.
Thu Mar 27 00:00:00 EDT 2014
Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity.
Cell reports
Toso A,Revandkar A,Di Mitri D,Guccini I,Proietti M,Sarti M,Pinton S,Zhang J,Kalathur M,Civenni G,Jarrossay D,Montani E,Marini C,Garcia-Escudero R,Scanziani E,Grassi F,Pandolfi PP,Catapano CV,Alimonti A
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that immune surveillance of senescent tumour cells can be suppressed in specific genetic backgrounds but also evoked by pharmacological treatments.
Thu Oct 09 00:00:00 EDT 2014
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
11-0452 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 EST 2013
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies.
The Journal of experimental medicine
Molnarfi N,Schulze-Topphoff U,Weber MS,Patarroyo JC,Prod'homme T,Varrin-Doyer M,Shetty A,Linington C,Slavin AJ,Hidalgo J,Jenne DE,Wekerle H,Sobel RA,Bernard CC,Shlomchik MJ,Zamvil SS
11-0452 was used in Flow cytometry/Cell sorting to investigate the contribution of B cells to antigen presentation and pathogenic T cell activation in the multiple sclerosis model experimental autoimmune encephalomyelitis.
Mon Dec 16 00:00:00 EST 2013
Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.
The EMBO journal
Panda S,Zhang J,Tan NS,Ho B,Ding JL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Wed Nov 13 00:00:00 EST 2013
Reciprocal effects of rab7 deletion in activated and neglected T cells.
Autophagy
Roy SG,Stevens MW,So L,Edinger AL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2013
Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf.
Oncogene
Baumgartner F,Woess C,Pedit V,Tzankov A,Labi V,Villunger A
11-0452 was used in Flow cytometry/Cell sorting to show that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation in mice.
Thu Jan 31 00:00:00 EST 2013
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
eLife
Olive V,Sabio E,Bennett MJ,De Jong CS,Biton A,McGann JC,Greaney SK,Sodir NM,Zhou AY,Balakrishnan A,Foth M,Luftig MA,Goga A,Speed TP,Xuan Z,Evan GI,Wan Y,Minella AC,He L
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunohistochemistry
Tue Oct 15 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kipari T,Hadoke PW,Iqbal J,Man TY,Miller E,Coutinho AE,Zhang Z,Sullivan KM,Mitic T,Livingstone DE,Schrecker C,Samuel K,White CI,Bouhlel MA,Chinetti-Gbaguidi G,Staels B,Andrew R,Walker BR,Savill JS,Chapman KE,Seckl JR
11-0452 was used in Flow cytometry/Cell sorting to determine the effects of 11Β-Hydroxysteroid dehydrogenase type-1 deficiency on atherosclerosis and its inflammation.
Mon Apr 01 00:00:00 EDT 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
11-0452 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Flaczyk A,Duerr CU,Shourian M,Lafferty EI,Fritz JH,Qureshi ST
11-0452 was used in Flow cytometry/Cell sorting to study how allergic patterns of lung inflammation are mediated as a host response to Cryptococcus neoformans infection.
Sun Sep 01 00:00:00 EDT 2013
Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response.
Journal of immunology (Baltimore, Md. : 1950)
Anginot A,Espeli M,Chasson L,Mancini SJ,Schiff C
11-0452 was used in Flow cytometry/Cell sorting to elucidate the pattern of GAL1 expression and the function of GAL1 in B cells.
Sat Jun 01 00:00:00 EDT 2013
IRF7-dependent IFN-β production in response to RANKL promotes medullary thymic epithelial cell development.
Journal of immunology (Baltimore, Md. : 1950)
Otero DC,Baker DP,David M
11-0452 was used in Flow cytometry/Cell sorting to study the role of IRF 3/7 and type I IFNs on thymic development.
Mon Apr 01 00:00:00 EDT 2013
Uterine natural killer cells severely decrease in number at gestation day 6 in mice.
Biology of reproduction
Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T
11-0452 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.
Tue Oct 01 00:00:00 EDT 2013
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype.
Virology journal
Ellis BL,Hirsch ML,Barker JC,Connelly JP,Steininger RJ,Porteus MH
11-0452 was used in Flow cytometry/Cell sorting to produce a comprehensive study of the transduction efficiency of viral vectors.
Wed Mar 06 00:00:00 EST 2013
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.
Journal of hematology & oncology
Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW
11-0452 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.
Tue Oct 01 00:00:00 EDT 2013
γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.
Immunity
Zeng X,Wei YL,Huang J,Newell EW,Yu H,Kidd BA,Kuhns MS,Waters RW,Davis MM,Weaver CT,Chien YH
11-0452 was used in Flow cytometry/Cell sorting to study the γδ T cell response to the algae protein, phycoerythrin.
Fri Sep 21 00:00:00 EDT 2012
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
11-0452 was used in Flow cytometry/Cell sorting to reveal the specificity of E2F8 in mediating Rb function in erythropoiesis.
Thu May 10 00:00:00 EDT 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
11-0452-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Do JS,Valujskikh A,Vignali DA,Fairchild RL,Min B
11-0452 was used in Flow cytometry/Cell sorting to reveal a previously undefined MHC II-dependent regulation that tunes CD8 T-cell reactivity.
Tue Jul 31 00:00:00 EDT 2012
Type II NKT cells facilitate Alum-sensing and humoral immunity.
Journal of leukocyte biology
Shah HB,Devera TS,Rampuria P,Lang GA,Lang ML
11-0452 was used in Flow cytometry/Cell sorting to show that type II NKT cells function as part of the Alum-sensing apparatus and in a CD1d-dependent manner, facilitate T(H)2-driven humoral immunity.
Mon Oct 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Journal of immunology (Baltimore, Md. : 1950)
Hasham MG,Snow KJ,Donghia NM,Branca JA,Lessard MD,Stavnezer J,Shopland LS,Mills KD
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Cowan JE,Baik S,Parnell SM,White AJ,Penninger JM,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
11-0452 was used in Flow cytometry/Cell sorting to study how multiple hemopoietic cell types regulate mTEC development through differential provision of RANKL/CD40L during ontogeny, revealing molecular differences in foetal and adult hemopoietic cross-talk.
Sat Dec 15 00:00:00 EST 2012
TRAF binding is required for a distinct subset of in vivo B cell functions of the oncoprotein LMP1.
Journal of immunology (Baltimore, Md. : 1950)
Arcipowski KM,Bishop GA
11-0452 was used in Flow cytometry/Cell sorting to investigate whether the mechanism of action of TRAF proteins for LMP1 in vivo functions requires direct association.
Sat Dec 01 00:00:00 EST 2012
Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice.
Journal of immunology (Baltimore, Md. : 1950)
Iwata Y,Boström EA,Menke J,Rabacal WA,Morel L,Wada T,Kelley VR
11-0452 was used in Flow cytometry/Cell sorting to elucidate the macrophage-associated effects of CSF-1 expression by tubular epithelial cells during kidney inflammation.
Tue May 01 00:00:00 EDT 2012
Gene expression profile and functionality of ESC-derived Lin-ckit+Sca-1+ cells are distinct from Lin-ckit+Sca-1+ cells isolated from fetal liver or bone marrow.
PloS one
Fernandez I,Fridley KM,Arasappan D,Ambler RV,Tucker PW,Roy K
11-0452 was used in Flow cytometry/Cell sorting to investigate whether whether in vitro ESC-derived progenitors have similar gene expression profiles and functionalities as their in vivo counterparts.
Wed Jul 17 00:00:00 EDT 2013
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.
Molecular therapy : the journal of the American Society of Gene Therapy
Ronen K,Negre O,Roth S,Colomb C,Malani N,Denaro M,Brady T,Fusil F,Gillet-Legrand B,Hehir K,Beuzard Y,Leboulch P,Down JD,Payen E,Bushman FD
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that β-thalassemia gene correction in mice can be achieved without the expansion of cells harbouring vectors integrated near growth control genes.
Fri Jul 01 00:00:00 EDT 2011
UV exposure boosts transcutaneous immunization and improves tumor immunity: cytotoxic T-cell priming through the skin.
The Journal of investigative dermatology
Stein P,Rechtsteiner G,Warger T,Bopp T,Fuhr T,Prüfer S,Probst HC,Stassen M,Langguth P,Schild H,Radsak MP
11-0452 was used in Flow Cytometry to explore the effects of ultraviolet irradiation on imiquimod-based transcutaneous immunisation.
Sat Jan 01 00:00:00 EST 2011
T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.
PLoS pathogens
Bockstal V,Guirnalda P,Caljon G,Goenka R,Telfer JC,Frenkel D,Radwanska M,Magez S,Black SJ
11-0452 was used in Flow cytometry/Cell sorting to study how infection-induced deletion of transitional B cells prevents replenishment of mature B cell compartments during T. brucei infection.
Wed Jun 01 00:00:00 EDT 2011
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.
Immunology
Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL
11-0452 was used in Flow cytometry/Cell sorting to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.
Tue Feb 01 00:00:00 EST 2011
Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo.
Development (Cambridge, England)
Oyama T,Harigaya K,Sasaki N,Okamura Y,Kokubo H,Saga Y,Hozumi K,Suganami A,Tamura Y,Nagase T,Koga H,Nishimura M,Sakamoto R,Sato M,Yoshida N,Kitagawa M
11-0452 was used in Western Blotting to indicate that engagement of Mam is essential for Notch signaling, and that the three Mam isoforms have distinct roles in vivo.
Thu Dec 01 00:00:00 EST 2011
Analysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.
Journal of immunology (Baltimore, Md. : 1950)
Simard N,Konforte D,Tran AH,Esufali J,Leonard WJ,Paige CJ
11-0452 was used in Flow cytometry/Cell sorting to provide evidence that IL-21R is functional in B cell progenitors and indicate that IL-21 regulates B cell development.
Sun May 01 00:00:00 EDT 2011
Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape.
Journal of immunology (Baltimore, Md. : 1950)
Duong BH,Ota T,Aoki-Ota M,Cooper AB,Ait-Azzouzene D,Vela JL,Gavin AL,Nemazee D
11-0452 was used in Flow cytometry/Cell sorting to demonstrate the usefulness of reconstituted IgM(b) superantigen hosts in revealing pathways involved in central tolerance.
Thu Dec 01 00:00:00 EST 2011
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Landrigan A,Wong MT,Utz PJ
11-0452 was used in Flow cytometry/Cell sorting to study the ability of oligodeoxynucleotides to activate and polarise T cells.
Thu Sep 15 00:00:00 EDT 2011
Inhibition of SOCS1-/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3+ regulatory T cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Collins EL,Jager LD,Dabelic R,Benitez P,Holdstein K,Lau K,Haider MI,Johnson HM,Larkin J
11-0452 was used in Flow cytometry/Cell sorting to show that CD4(+)/SOCS1-KIR combined treatment can synergistically promote the long-term survival of perinatal lethal SOCS1(-/-) mice.
Thu Sep 01 00:00:00 EDT 2011
CCR6hiCD11c(int) B cells promote M-cell differentiation in Peyer's patch.
International immunology
Ebisawa M,Hase K,Takahashi D,Kitamura H,Knoop KA,Williams IR,Ohno H
11-0452 was used in Flow cytometry/Cell sorting to suggest that the spatial regulation of CCR6(hi)CD11c(int) B cells via the CCL20-CCR6 system may play a vital role in M-cell differentiation.
Fri Apr 01 00:00:00 EDT 2011
Immunization with apoptotic phagocytes containing Histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis.
Infection and immunity
Hsieh SH,Lin JS,Huang JH,Wu SY,Chu CL,Kung JT,Wu-Hsieh BA
11-0452 was used in Immunofluorescence on frozen tissues to investigate the effect of immunisation with apoptotic phagocytes containing heat-killed Histoplasma, showing that it activates functional CD8(+) T cells to protect against histoplasmosis.
Tue Nov 01 00:00:00 EDT 2011
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.
PloS one
Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2011
T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival.
PloS one
Moro H,Otero DC,Tanabe Y,David M
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that type I interferons and STAT1 play an important role in the survival of MHC class I-restricted T cells.
Fri Feb 03 00:00:00 EST 2012
Acute Disruption of Bone Marrow B Lymphopoiesis and Apoptosis of Transitional and Marginal Zone B Cells in the Spleen following a Blood-Stage Plasmodium chabaudi Infection in Mice.
Journal of parasitology research
Bockstal V,Geurts N,Magez S
11-0452 was used in Flow cytometry/Cell sorting to investigate the effects of a blood-stage Plasmodium chabaudi infection in the spleen and bone marrow of mice.
Thu Jul 14 00:00:00 EDT 2011
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
Blood
Huber S,Hoffmann R,Muskens F,Voehringer D
11-0452 was used in Flow cytometry/Cell sorting to study how IL-4 induced the expression of PD-L2 on CAM, and LPS increased the expression of PD-L1 on alternatively activated macrophages.
Thu Oct 28 00:00:00 EDT 2010
Measles virus-induced immunosuppression in SLAM knock-in mice.
Journal of virology
Koga R,Ohno S,Ikegame S,Yanagi Y
11-0452 was used in Flow cytometry/Cell sorting to generate a model to investigate the mechanism by which the measles virus causes immunosuppression, showing that SLAM knock-in mice lacking the expression of the alpha/beta-interferon receptor could serve as a model.
Sat May 01 00:00:00 EDT 2010
Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Santiago ML,Benitez RL,Montano M,Hasenkrug KJ,Greene WC
11-0452 was used in Flow cytometry/Cell sorting to propose that enabling Apobec3 activity during acute infection with human pathogenic retroviruses may similarly facilitate stronger virus-specific neutralizing Ab responses.
Thu Jul 15 00:00:00 EDT 2010
Impaired apoptotic cell clearance in the germinal center by Mer-deficient tingible body macrophages leads to enhanced antibody-forming cell and germinal center responses.
Journal of immunology (Baltimore, Md. : 1950)
Rahman ZS,Shao WH,Khan TN,Zhen Y,Cohen PL
11-0452 was used in Flow cytometry/Cell sorting to demonstrate a critical role for Mer in GC apoptotic cell clearance by TBMΦs.
Mon Nov 15 00:00:00 EST 2010
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Do JS,Fink PJ,Li L,Spolski R,Robinson J,Leonard WJ,Letterio JJ,Min B
11-0452 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying the generation of gammadelta T cells, showing that it occurs via a TGF-beta 1-dependent mechanism.
Mon Feb 15 00:00:00 EST 2010
CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection.
Infection and immunity
Eppert BL,Motz GT,Wortham BW,Flury JL,Borchers MT
11-0452 was used in Flow cytometry/Cell sorting to investigate the roles of CCR7 in the host defense against pulmonary infection, showing that CCR7 deficiency leads to leukocyte activation and increased infection clearance.
Sat May 01 00:00:00 EDT 2010
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production.
Blood
Qi Q,Xia M,Hu J,Hicks E,Iyer A,Xiong N,August A
11-0452 was used in Flow cytometry/Cell sorting to investigate the effect of Itk on T cell populations, showing that development of CD4+ gammadelta T cells is enhanced and IgE production is elevated in the absence of Itk.
Thu Jul 16 00:00:00 EDT 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
11-0452 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 EDT 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
11-0452 was used in Flow cytometry/Cell sorting to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 EDT 2009
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Blood
Rubinstein MP,Lind NA,Purton JF,Filippou P,Best JA,McGhee PA,Surh CD,Goldrath AW
11-0452 was used in Flow cytometry/Cell sorting to study IL-7 and IL-15 regulation of CD8+ T-cell subsets during contraction of the immune response.
Sat Nov 01 00:00:00 EDT 2008
CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.
Journal of the American Society of Nephrology : JASN
Menke J,Zeller GC,Kikawada E,Means TK,Huang XR,Lan HY,Lu B,Farber J,Luster AD,Kelley VR
11-0452 was used in Flow cytometry/Cell sorting to identify additional therapeutic chemokine targets for immune-mediated nephritis.
Sun Jun 01 00:00:00 EDT 2008
p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.
PloS one
Cheng N,van de Wetering CI,Knudson CM
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2008
Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection.
Journal of virology
Ohno S,Ono N,Seki F,Takeda M,Kura S,Tsuzuki T,Yanagi Y
11-0452 was used in Flow cytometry/Cell sorting to investigate the effects on measles infection after replacement of the V domain of mouse SLAM with human SLAM.
Thu Feb 01 00:00:00 EST 2007
Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells--molecular basis of their trafficking to lymph nodes.
International immunology
Matsutani T,Tanaka T,Tohya K,Otani K,Jang MH,Umemoto E,Taniguchi K,Hayasaka H,Ueda K,Miyasaka M
11-0452 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms of plasmacytoid dendritic cell migration using freshly isolated dendritic cells and high endothelial venule cells.
Sat Sep 01 00:00:00 EDT 2007
Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing.
Molecular and cellular biology
Bai L,Chen Y,He Y,Dai X,Lin X,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2007
Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk.
Blood
Takizawa H,Kubo-Akashi C,Nobuhisa I,Kwon SM,Iseki M,Taga T,Takatsu K,Takaki S
11-0452 was used in Flow cytometry/Cell sorting to investigate the potential of Lnk for augmented engraftment of HSCs.
Sat Apr 01 00:00:00 EST 2006
Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth.
Proceedings of the National Academy of Sciences of the United States of America
Kikuchi K,Kondo M
11-0452 was used in Flow cytometry/Cell sorting to demonstrate how foetal haematopoietic stem cells may acquire adult characteristics between 1 and 2 weeks after birth in mouse bone marrow.
Tue Nov 21 00:00:00 EST 2006
Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.
Molecular and cellular biology
Wen R,Chen Y,Bai L,Fu G,Schuman J,Dai X,Zeng H,Yang C,Stephan RP,Cleveland JL,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006
Distinct roles of phosphoinositide-3 kinase and phospholipase Cgamma2 in B-cell receptor-mediated signal transduction.
Molecular and cellular biology
Dai X,Chen Y,Schuman J,Hua Z,Adamson JW,Wen R,Wang D
11-0452 was used in Flow cytometry/Cell sorting to investigate the functional relationship between PI3K and PLCgamma2, and their independent functions in BCR signal transduction.
Sun Jan 01 00:00:00 EST 2006
A role for brain-derived neurotrophic factor in B cell development.
Journal of neuroimmunology
Schuhmann B,Dietrich A,Sel S,Hahn C,Klingenspor M,Lommatzsch M,Gudermann T,Braun A,Renz H,Nockher WA
Wed Jun 01 00:00:00 EDT 2005
Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.
The Journal of experimental medicine
Shiratori I,Ogasawara K,Saito T,Lanier LL,Arase H
11-0452 was used in Magnetic cell separation to reveal a new regulatory mechanism of innate immunity by PILR and its CD99-like ligand.
Mon Feb 16 00:00:00 EST 2004
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
Molecular and cellular biology
Pan L,Sato S,Frederick JP,Sun XH,Zhuang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 11-0452-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 1999
-RA3-6B2-RE-AV-20170920122035.jpg?time=20240507)
-RA3-6B2-RE-AV-20170920122035.jpg?time=20240507?time=20240507 "CD45R (B220) Antibody (11-0452-82)")
