Product References
Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy.
NPJ vaccines
Teymournejad O,Li Z,Beesetty P,Yang C,Montgomery CP
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Jan 24 00:00:00 EST 2023
NCR negative group 3 innate lymphoid cell (NCR- ILC3) participates in abnormal pathology of lung in cigarette smoking-induced COPD mice.
Immunity, inflammation and disease
Chu S,Ma L,Yang X,Xiao B,Liang Y,Zheng S,Li L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis.
The Journal of experimental medicine
Kim TS,Silva LM,Theofilou VI,Greenwell-Wild T,Li L,Williams DW,Ikeuchi T,Brenchley L,Bugge TH,Diaz PI,Kaplan MJ,Carmona-Rivera C,Moutsopoulos NM
11-0031-82 was used in Immunohistochemistry to suggest a feed-forward loop in which NETs trigger IL-17 immunity to promote immunopathology in a prevalent human inflammatory disease.
Mon Sep 04 00:00:00 EDT 2023
A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy.
British journal of pharmacology
Wang Y,Gao J,Yu Y,Zhou L,Wang M,Xue W,Liu B,Wu X,Wu X,Gao H,Shen Y,Xu Q
11-0031-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to reveal that CA-e is a novel GR modulator with strong potency to attenuate the side effects of GC therapy and can be used as a potential molecular tool for deciphering GR signalling.
Sun Jan 01 00:00:00 EST 2023
Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice.
Aging and disease
Elsayed R,Elashiry M,Liu Y,Morandini AC,El-Awady A,Elashiry MM,Hamrick M,Cutler CW
11-0031-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to conclude that immune senescence, compounded by advanced age, and accelerated by oral dysbiosis and its induced SASP exosomes, plays a pivotal role in the pathophysiology of experimental periodontitis.
Wed Feb 01 00:00:00 EST 2023
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development.
Cancer nanotechnology
Sun W,Dai L,Cao Y,Pan P,Zhi L,Wang X,Yuan X,Gao Z,Guo S,Liu G,Yin J,Xie L,Wang L,Wang Y,Li W,Li H,Jia Y
11-0031-82 was used in Flow cytometry/Cell sorting to provide novel vaccination strategy for the development of tumor vaccines and facilitate the application of T-MPs for clinic oncotherapy.
Tue Apr 25 00:00:00 EDT 2023
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
Diabetes
Luan D,Dadpey B,Zaid J,Bridge-Comer PE,DeLuca JH,Xia W,Castle J,Reilly SM
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia.
Cell death and differentiation
Li X,Li F,Zhang X,Zhang H,Zhao Q,Li M,Wu X,Wang L,Liu J,Wu X,Ou Y,Xing M,Zhang Y,Deng J,Wang X,Luo Y,Li J,Zhao Y,Zhang H
11-0031-82 was used in Flow Cytometry to demonstrate previously unappreciated roles for caspase-8 auto-cleavage in regulating necroptosis and maintaining lymphocytes homeostasis.
Mon Aug 01 00:00:00 EDT 2022
ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function.
Aging
Meng W,Li Z,Zhang Y,Yang A,Wang Y,Zhou Y,Wu W,Qiu Y,Li L
11-0031-82 was used in Flow cytometry/Cell sorting to provide the experimental basis for the application of ZQFZ as a therapeutic agent for CRC.
Wed Jun 08 00:00:00 EDT 2022
Pomegranate Peel Extract Decreases Plaque Necrosis and Advanced Atherosclerosis Progression in Apoe Mice.
Frontiers in pharmacology
Manickam V,Dhawan UK,Singh D,Gupta M,Subramanian M
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sat Jul 16 00:00:00 EDT 2022
Caspase-8 Blocks Receptor-Interacting Protein Kinase-1 Kinase-Independent Necroptosis during Embryogenesis.
ImmunoHorizons
Zhang H,Wu X,Li M,Li X,Wang L,Liu J,Ou Y,Wu X,Xing M,Li F,Zhao X,Liu H,Jones C,Deng J,Xie Q,Zhang Y,Luo Y,Zhao Y,Zhang H
11-0031-82 was used in Flow cytometry/Cell sorting to investigate the detailed mechanisms by which Casp8 deficiency triggers necroptosis during embryonic development remain unclear.
Wed Jul 20 00:00:00 EDT 2022
Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa.
Cell reports
Stienne C,Virgen-Slane R,Elmén L,Veny M,Huang S,Nguyen J,Chappell E,Balmert MO,Shui JW,Hurchla MA,Kronenberg M,Peterson SN,Murphy KM,Ware CF,Šedý JR
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Tue Mar 22 00:00:00 EDT 2022
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
International journal of molecular sciences
Zou Y,Wang X,Xu J,Wang S,Li S,Zhu Y,Wang J
11-0031-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to reveal that Z. morio hemolymph alleviates E. coli-induced mastitis via lessening the inflammatory response by regulating the NLRP3 and ATG5/ATG16L1 signaling pathway, as well as repairing the blood-milk barrier.
Mon Oct 31 00:00:00 EDT 2022
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.
Immunity
Medina CB,Chiu YH,Stremska ME,Lucas CD,Poon I,Tung KS,Elliott MR,Desai B,Lorenz UM,Bayliss DA,Ravichandran KS
11-0031-82 was used in Flow cytometry/Cell sorting to uncover an immunoregulatory role for the nucleotide release channel, Panx1, in T cell crosstalk during airway disease.
Tue Aug 10 00:00:00 EDT 2021
Cold exposure protects from neuroinflammation through immunologic reprogramming.
Cell metabolism
Spiljar M,Steinbach K,Rigo D,Suárez-Zamorano N,Wagner I,Hadadi N,Vincenti I,Page N,Klimek B,Rochat MA,Kreutzfeldt M,Chevalier C,Stojanović O,Bejuy O,Colin D,Mack M,Cansever D,Greter M,Merkler D,Trajkovski M
11-0031-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) to propose a mechanistic link between environmental temperature and neuroinflammation and suggest competition between cold-induced metabolic adaptations and autoimmunity as energetic trade-off beneficial for the immune-mediated diseases.
Tue Nov 02 00:00:00 EDT 2021
HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.
Cell stem cell
Lv K,Gong C,Antony C,Han X,Ren JG,Donaghy R,Cheng Y,Pellegrino S,Warren AJ,Paralkar VR,Tong W
11-0031-82 was used in Flow cytometry/Cell sorting to reveal a role of the E3 ubiquitin ligase HectD1 in regulating HSC function via ribosome assembly and protein translation.
Thu Jul 01 00:00:00 EDT 2021
Lymph node formation and B cell homeostasis require IKK-α in distinct endothelial cell-derived compartments.
Proceedings of the National Academy of Sciences of the United States of America
McCorkell KA,Jayachandran N,Cully MD,Freund-Brown J,Weinkopff T,Monslow J,Hu Y,Puré E,Freedman BD,Alvarez JI,Cancro MP,May MJ
11-0031-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry to reveal that IKK-α in distinct EC-derived compartments is uniquely required to promote B cell homeostasis and LN development, and establish that LEC-intrinsic IKK-α is absolutely essential for LN formation.
Tue Nov 30 00:00:00 EST 2021
Lymph node formation and B cell homeostasis require IKK-α in distinct endothelial cell-derived compartments.
Proceedings of the National Academy of Sciences of the United States of America
McCorkell KA,Jayachandran N,Cully MD,Freund-Brown J,Weinkopff T,Monslow J,Hu Y,Puré E,Freedman BD,Alvarez JI,Cancro MP,May MJ
11-0031-82 was used in Immunohistochemistry (Frozen), Immunohistochemistry to reveal that IKK-α in distinct EC-derived compartments is uniquely required to promote B cell homeostasis and LN development, and establish that LEC-intrinsic IKK-α is absolutely essential for LN formation.
Tue Nov 30 00:00:00 EST 2021
A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface.
Journal of cellular and molecular medicine
Wei DP,Li DD,Gu AQ,Ji WH,Yang Y,Peng JP
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.
The European journal of neuroscience
Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity.
The Journal of biological chemistry
McAndrews KM,Che SPY,LeBleu VS,Kalluri R
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Aug 20 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sat Jan 30 00:00:00 EST 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sat Jan 30 00:00:00 EST 2021
Obesity results in adipose tissue T cell exhaustion.
JCI insight
Porsche CE,Delproposto JB,Geletka L,O'Rourke R,Lumeng CN
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Apr 22 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization.
Nature communications
Zhang L,Zhang K,Zhang J,Zhu J,Xi Q,Wang H,Zhang Z,Cheng Y,Yang G,Liu H,Guo X,Zhou D,Xue Z,Li Y,Zhang Q,Da Y,Liu L,Yin Z,Yao Z,Zhang R
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Jul 14 00:00:00 EDT 2021
Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE-/- mice in the presence and absence of immunomodulation with fingolimod.
Data in brief
Diaz Diaz AC,Malone K,Shearer JA,Moore AC,Waeber C
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Oct 07 00:00:00 EDT 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Expanded renal lymphatics improve recovery following kidney injury.
Physiological reports
Baranwal G,Creed HA,Black LM,Auger A,Quach AM,Vegiraju R,Eckenrode HE,Agarwal A,Rutkowski JM
11-0031-82 was used in Flow cytometry/Cell sorting to demonstrate that increased lymphatic density prior to injury alters the injury recovery response and affords protection from CKD progression.
Mon Nov 01 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
11-0031-82 was used in Flow Cytometry to support the therapeutic potential of placenta-derived stromal cells for select physiological deficits during simulated spaceflight.
Mon Apr 19 00:00:00 EDT 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Nature medicine
Koelwyn GJ,Newman AAC,Afonso MS,van Solingen C,Corr EM,Brown EJ,Albers KB,Yamaguchi N,Narke D,Schlegel M,Sharma M,Shanley LC,Barrett TJ,Rahman K,Mezzano V,Fisher EA,Park DS,Newman JD,Quail DF,Nelson ER,Caan BJ,Jones LW,Moore KJ
11-0031 was used in Flow cytometry/Cell sorting to show that myocardial infarction (MI) accelerates breast cancer outgrowth and cancer-specific mortality in mice and humans. I.
Tue Sep 01 00:00:00 EDT 2020
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
Sadik A,Somarribas Patterson LF,Öztürk S,Mohapatra SR,Panitz V,Secker PF,Pfänder P,Loth S,Salem H,Prentzell MT,Berdel B,Iskar M,Faessler E,Reuter F,Kirst I,Kalter V,Foerster KI,Jäger E,Guevara CR,Sobeh M,Hielscher T,Poschet G,Reinhardt A,Hassel JC,Zapatka M,Hahn U,von Deimling A,Hopf C,Schlichting R,Escher BI,Burhenne J,Haefeli WE,Ishaque N,Böhme A,Schäuble S,Thedieck K,Trump S,Seiffert M,Opitz CA
11-0031 was used in Flow cytometry/Cell sorting to show that IL4I1 blockade opens new avenues for cancer therapy.
Thu Sep 03 00:00:00 EDT 2020
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses.
Immunity
Ma X,Zou F,Yu F,Li R,Yuan Y,Zhang Y,Zhang X,Deng J,Chen T,Song Z,Qiao Y,Zhan Y,Liu J,Zhang J,Zhang X,Peng Z,Li Y,Lin Y,Liang L,Wang G,Chen Y,Chen Q,Pan T,He X,Zhang H
11-0031 was used in Flow cytometry/Cell sorting to develop nanoparticle vaccines by covalently conjugating the self-assembled 24-mer ferritin to the receptor binding domain (RBD) and/or heptad repeat (HR) subunits of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) spike (S) protein.
Tue Dec 15 00:00:00 EST 2020
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Immunity
Tummers B,Mari L,Guy CS,Heckmann BL,Rodriguez DA,Rühl S,Moretti J,Crawford JC,Fitzgerald P,Kanneganti TD,Janke LJ,Pelletier S,Blander JM,Green DR
11-0031-82 was used in Flow Cytometry to suggest an in vivo role of the inflammatory RIPK1-caspase-8-FADD (FADDosome) complex and reveal a FADD-independent inflammatory role of caspase-8 that involves activation of an inflammasome.
Tue Jun 16 00:00:00 EDT 2020
BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse.
Cell stem cell
Jia L,Zhang W,Wang CY
11-0031-82 was used in Flow Cytometry to suggest that targeting BMI1 may enable immune checkpoint blockade to inhibit metastatic tumor growth and prevent tumor relapse by activating cell-intrinsic immunity, in addition to purging CSCs.
Thu Aug 06 00:00:00 EDT 2020
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair.
Cell stem cell
Shook BA,Wasko RR,Mano O,Rutenberg-Schoenberg M,Rudolph MC,Zirak B,Rivera-Gonzalez GC,López-Giráldez F,Zarini S,Rezza A,Clark DA,Rendl M,Rosenblum MD,Gerstein MB,Horsley V
11-0031-82 was used in Flow Cytometry to identify an essential role for adipocyte lipolysis in regulating inflammation and repair after injury in skin.
Thu Jun 04 00:00:00 EDT 2020
Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells.
Brain, behavior, and immunity
Piras G,Rattazzi L,Paschalidis N,Oggero S,Berti G,Ono M,Bellia F,D'Addario C,Dell'Osso B,Pariante CM,Perretti M,D'Acquisto F
11-0031-82 was used in Flow Cytometry to identify a novel factor, a small protein of approximately 21 kDa encoded by the gene 2610019F03Rik, thus named Immuno-moodulin, associated with overexpressing Annexin-A1 exclusively in T cells, as a novel peripheral determinant that modulates anxiety behavior.
Wed Jul 01 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.
PLoS biology
Kobia FM,Preusse K,Dai Q,Weaver N,Hass MR,Chaturvedi P,Stein SJ,Pear WS,Yuan Z,Kovall RA,Kuang Y,Eafergen N,Sprinzak D,Gebelein B,Brunskill EW,Kopan R
11-0031 was used in Flow cytometry/Cell sorting to highlight the role of the environment in malignancy and colitis and is consistent with Notch-dependent anti-parasite immune responses being compromised in Notch dimer-deficient animals.
Thu Oct 01 00:00:00 EDT 2020
Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.
PLoS pathogens
Still KM,Batista SJ,O'Brien CA,Oyesola OO,Früh SP,Webb LM,Smirnov I,Kovacs MA,Cowan MN,Hayes NW,Thompson JA,Tait Wojno ED,Harris TH
11-0031 was used in Flow cytometry/Cell sorting to show that IL-33 is expressed by oligodendrocytes and astrocytes during T. gondii infection, is released locally into the cerebrospinal fluid of T. gondii-infected animals, and is required for control of infection.
Thu Oct 01 00:00:00 EDT 2020
Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.
Journal of virology
Busse DC,Habgood-Coote D,Clare S,Brandt C,Bassano I,Kaforou M,Herberg J,Levin M,Eléouët JF,Kellam P,Tregoning JS
11-0031 was used in Flow cytometry/Cell sorting to investigate IFI44 and IFI44L as they are upregulated after a wide range of viral infections, and IFI44L can serve as a diagnostic biomarker of viral infection.
Mon Aug 31 00:00:00 EDT 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Journal of cellular and molecular medicine
Cong LH,Li T,Wang H,Wu YN,Wang SP,Zhao YY,Zhang GQ,Duan J
11-0031 was used in Flow cytometry/Cell sorting to suggest that PM2.5 could inhibit autophagy of bronchial epithelial cells and promote pulmonary inflammation and fibrosis by inducing the secretion of IL-17A in γδT and Th17 cells and regulating the PI3K/Akt/mTOR signalling pathway.
Sat Aug 01 00:00:00 EDT 2020
High-fat diet induced central adiposity (visceral fat) is associated with increased fibrosis and decreased immune cellularity of the mesenteric lymph node in mice.
European journal of nutrition
Magnuson AM,Regan DP,Booth AD,Fouts JK,Solt CM,Hill JL,Dow SW,Foster MT
11-0031-82 was used in Flow Cytometry to investigate if lymph nodes are inherently distinct and differentially respond to diet-induced obesity much like the adipose depots they reside in.
Mon Jun 01 00:00:00 EDT 2020
Impact of S1P Mimetics on Mesenteric Ischemia/Reperfusion Injury.
Pharmaceuticals (Basel, Switzerland)
Potì F,Giorgio C,Zini I,Nofer JR,Vivo V,Palese S,Ballabeni V,Barocelli E,Bertoni S
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Oct 09 00:00:00 EDT 2020
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions.
FEBS open bio
Liu Y,Gao Y,Hao H,Hou T
11-0031 was used in Flow cytometry/Cell sorting to show that antibody-mediated inhibition of CD279 reduces T cell survival in bone marrow in vivo.
Mon Jun 01 00:00:00 EDT 2020
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions.
FEBS open bio
Liu Y,Gao Y,Hao H,Hou T
11-0031 was used in Flow cytometry/Cell sorting to show that antibody-mediated inhibition of CD279 reduces T cell survival in bone marrow in vivo.
Mon Jun 01 00:00:00 EDT 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Apr 28 00:00:00 EDT 2021
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Communications biology
Pflügler S,Svinka J,Scharf I,Crncec I,Filipits M,Charoentong P,Tschurtschenthaler M,Kenner L,Awad M,Stift J,Schernthanner M,Bischl R,Herndler-Brandstetter D,Glitzner E,Moll HP,Casanova E,Timelthaler G,Sibilia M,Gnant M,Lax S,Thaler J,Müller M,Strobl B,Mohr T,Kaser A,Trajanoski Z,Heller G,Eferl R
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity.
Cell reports
Fuster JJ,Zuriaga MA,Zorita V,MacLauchlan S,Polackal MN,Viana-Huete V,Ferrer-Pérez A,Matesanz N,Herrero-Cervera A,Sano S,Cooper MA,González-Navarro H,Walsh K
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.
Cell reports
Parikh BA,Bern MD,Piersma SJ,Yang L,Beckman DL,Poursine-Laurent J,Plougastel-Douglas B,Yokoyama WM
11-0031 was used in Flow cytometry/Cell sorting to show MHC-I-restricted control of murine cytomegalovirus (MCMV) infection in vivo that is NK cell dependent.
Tue Jul 28 00:00:00 EDT 2020
Tumor microenvironment remodeling by an engineered oncolytic adenovirus results in improved outcome from PD-L1 inhibition.
Oncoimmunology
Cervera-Carrascon V,Quixabeira DCA,Santos JM,Havunen R,Zafar S,Hemminki O,Heiniö C,Munaro E,Siurala M,Sorsa S,Mirtti T,Järvinen P,Mildh M,Nisen H,Rannikko A,Anttila M,Kanerva A,Hemminki A
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays.
Frontiers in immunology
Finetti F,Capitani N,Manganaro N,Tatangelo V,Libonati F,Panattoni G,Calaresu I,Ballerini L,Baldari CT,Patrussi L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunocytochemistry
Mon Mar 08 00:00:00 EST 2021
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays.
Frontiers in immunology
Finetti F,Capitani N,Manganaro N,Tatangelo V,Libonati F,Panattoni G,Calaresu I,Ballerini L,Baldari CT,Patrussi L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunocytochemistry
Mon Mar 08 00:00:00 EST 2021
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.
Cell death & disease
Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY
11-0031 was used in Flow cytometry/Cell sorting to elucidate the underlying antitumor mechanism of ZD55-IL-24 in both immunocompetent and immunocompromised mouse model.
Mon Nov 30 00:00:00 EST 2020
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Cell reports
Viaud M,Abdel-Wahab O,Gall J,Ivanov S,Guinamard R,Sore S,Merlin J,Ayrault M,Guilbaud E,Jacquel A,Auberger P,Wang N,Levine RL,Tall AR,Yvan-Charvet L
11-0031 was used in Flow cytometry/Cell sorting to identify somatic mutations in ABCA1 that subvert its anti-proliferative and cholesterol efflux functions and permit the progression of myeloid neoplasms.
Tue Mar 10 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
11-0031-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis.
Scientific reports
Monteran L,Ershaid N,Sabah I,Fahoum I,Zait Y,Shani O,Cohen N,Eldar-Boock A,Satchi-Fainaro R,Erez N
11-0031 was used in Flow cytometry/Cell sorting to characterise the intrinsic changes in breast cancer cells that facilitate bone-tropism and found that they acquire mesenchymal and osteomimetic features.
Fri Aug 14 00:00:00 EDT 2020
Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.
Frontiers in immunology
Zhang Z,Lu S,Dunmall LSC,Wang Z,Cheng Z,Zhang Z,Yan W,Chu Y,Gao D,Wang N,Li Y,Wang J,Li Y,Ji Y,Shan D,Li K,Wang P,Dong Y,Dong J,Lemoine NR,Pei D,Zhang L,Wang Y
11-0031 was used in Flow cytometry/Cell sorting to establish how a Virus-Infected Reprogrammed Somatic cell-derived Tumor cell (VIReST) vaccination regime can be utilised for treatment or prevention of lung cancer development in at-risk individuals.
Fri Apr 30 00:00:00 EDT 2021
Crucial Roles of the RIP Homotypic Interaction Motifs of RIPK3 in RIPK1-Dependent Cell Death and Lymphoproliferative Disease.
Cell reports
Zhang H,Wu X,Li X,Li M,Li F,Wang L,Zhang X,Zhang Y,Luo Y,Wang H,Jiang Y,Zhang H
11-0031 was used in Flow cytometry/Cell sorting to reveal a previously unidentified physiological function of RHIM of RIPK3 in regulating RIPK1-dependent cell death and lymphoproliferative disease.
Tue May 19 00:00:00 EDT 2020
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Cell reports
Castro-Dopico T,Fleming A,Dennison TW,Ferdinand JR,Harcourt K,Stewart BJ,Cader Z,Tuong ZK,Jing C,Lok LSC,Mathews RJ,Portet A,Kaser A,Clare S,Clatworthy MR
11-0031 was used in Flow cytometry/Cell sorting to identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients with IBD and mice with dextran sodium sulfate (DSS)-induced colitis.
Tue Jul 07 00:00:00 EDT 2020
Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.
Cells
Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J
11-0031 was used in Flow cytometry/Cell sorting to evaluate the potential of a bivalent carboxylate inhibitor to selectively inhibit the trimeric proteoform of MMP-9 and compare this with a corresponding monovalent inhibitor.
Tue Jul 07 00:00:00 EDT 2020
Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.
Cell
Davies AJ,Kim HW,Gonzalez-Cano R,Choi J,Back SK,Roh SE,Johnson E,Gabriac M,Kim MS,Lee J,Lee JE,Kim YS,Bae YC,Kim SJ,Lee KM,Na HS,Riva P,Latremoliere A,Rinaldi S,Ugolini S,Costigan M,Oh SB
11-0031 was used in Flow cytometry/Cell sorting to suggest the therapeutic potential of modulating NK cell function to resolve painful neuropathy through the clearance of partially damaged nerves.
Thu Feb 07 00:00:00 EST 2019
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.
Immunity
Roy K,Mitchell S,Liu Y,Ohta S,Lin YS,Metzig MO,Nutt SL,Hoffmann A
11-0031-82 was used in Flow Cytometry to provide a mechanistic explanation of how dysregulation of this bi-stable circuit might result in pathologic B cell population phenotypes and thus offer new avenues for diagnostic stratification and treatment.
Tue Mar 19 00:00:00 EDT 2019
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
11-0031 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Li S,Wu Y,Yang D,Wu C,Ma C,Liu X,Moynagh PN,Wang B,Hu G,Yang S
11-0031-82 was used in Flow Cytometry to study how GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS, leading to the suppression of neuroinflammation and demyelination.
Mon Nov 04 00:00:00 EST 2019
Depression-Induced Neuropeptide Y Secretion Promotes Prostate Cancer Growth by Recruiting Myeloid Cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Cheng Y,Tang XY,Li YX,Zhao DD,Cao QH,Wu HX,Yang HB,Hao K,Yang Y
11-0031 was used in Flow cytometry/Cell sorting to show that depression promotes myeloid cell infiltration and increases IL6 levels by a sympathetic-NPY signal. Sympathetic-NPY inhibition may be a promising strategy for patients with prostate cancer with high score of psychologic depression.
Mon Apr 15 00:00:00 EDT 2019
Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection.
Proceedings of the National Academy of Sciences of the United States of America
Zheng M,Li D,Zhao Z,Shytikov D,Xu Q,Jin X,Liang J,Lou J,Wu S,Wang L,Hu H,Zhou Y,Gao X,Lu L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in T-Cell Activation
Tue Jun 18 00:00:00 EDT 2019
GM-CSF Promotes Antitumor Immunity by Inducing Th9 Cell Responses.
Cancer immunology research
Kim IK,Koh CH,Jeon I,Shin KS,Kang TS,Bae EA,Seo H,Ko HJ,Kim BS,Chung Y,Kang CY
11-0031-82 was used in Flow Cytometry to demonstrate that GM-CSF potentiates the efficacy of cancer vaccines through IL9-producing Th (Th9) cells.
Fri Mar 01 00:00:00 EST 2019
1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension.
British journal of pharmacology
Mikolajczyk TP,Nosalski R,Skiba DS,Koziol J,Mazur M,Justo-Junior AS,Kowalczyk P,Kusmierczyk Z,Schramm-Luc A,Luc K,Maffia P,Graham D,Kiss AK,Naruszewicz M,Guzik TJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Clearance of Chikungunya Virus Infection in Lymphoid Tissues Is Promoted by Treatment with an Agonistic Anti-CD137 Antibody.
Journal of virology
Hong JP,McCarthy MK,Davenport BJ,Morrison TE,Diamond MS
11-0031 was used in Flow cytometry/Cell sorting to evaluate the activity of anti-CD137 MAb in a model of Chikungunya virus arthritis in immunocompetent C57BL/6 mice.
Sun Dec 15 00:00:00 EST 2019
CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Nature communications
Kim TJ,Park G,Kim J,Lim SA,Kim J,Im K,Shin MH,Fu YX,Del Rio ML,Rodriguez-Barbosa JI,Yee C,Suh KS,Kim SJ,Ha SJ,Lee KM
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jul 22 00:00:00 EDT 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
11-0031 was used in Flow cytometry/Cell sorting to investigate the underlying sex differences that may contribute to differential footpad delayed-type hypersensitivity responses using wildtype and four core genotypes mice and popliteal lymphnode cellularity and gene expression.
Wed Jan 30 00:00:00 EST 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
11-0031 was used in Flow cytometry/Cell sorting to investigate the underlying sex differences that may contribute to differential footpad delayed-type hypersensitivity responses using wildtype and four core genotypes mice and popliteal lymphnode cellularity and gene expression.
Wed Jan 30 00:00:00 EST 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
STAT1 signaling shields T cells from NK cell-mediated cytotoxicity.
Nature communications
Kang YH,Biswas A,Field M,Snapper SB
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Feb 22 00:00:00 EST 2019
KCa3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II -Treated Rats.
Journal of the American Heart Association
She G,Ren YJ,Wang Y,Hou MC,Wang HF,Gou W,Lai BC,Lei T,Du XJ,Deng XL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Western Blot
Tue Jan 08 00:00:00 EST 2019
Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.
Nature communications
Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H
11-0031-82 was used in Flow Cytometry to reveal a critical role of Lys376-mediated ubiquitination of RIPK1 in suppressing RIPK1 kinase activity-dependent lethal pathways during embryogenesis and RIPK3-dependent inflammation postnatally.
Fri Sep 13 00:00:00 EDT 2019
Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression.
Nature communications
Bae J,Choi SP,Isono K,Lee JY,Park SW,Choi CY,Han J,Kim SH,Lee HH,Park K,Jin HY,Lee SJ,Park CG,Koseki H,Lee YS,Chun T
11-0031-82 was used in Flow cytometry/Cell sorting to determine the role of PHc2 in controlling the mobilisation of hematopoietic stem and progenitor cells.
Fri Aug 02 00:00:00 EDT 2019
Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.
Cell reports
Ciecko AE,Foda B,Barr JY,Ramanathan S,Atkinson MA,Serreze DV,Geurts AM,Lieberman SM,Chen YG
11-0031-82 was used in Flow Cytometry to reveal that IL-27 contributes to autoimmunity in NOD mice through multiple mechanisms and provides substantial evidence to support its pathogenic role in human T1D.
Tue Dec 03 00:00:00 EST 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
11-0031-82 was used in Flow Cytometry to study the intrinsic mediators that render CD8+T cells dysfunctional in the tumour microenvironment.
Wed Mar 20 00:00:00 EDT 2019
A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities.
PloS one
Hodgins B,Pillet S,Landry N,Ward BJ
11-0031 was used in Flow cytometry/Cell sorting to potentially address some of the limitations of current vaccines in the elderly.
Mon Sep 30 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
11-0031 was used in Flow cytometry/Cell sorting to show that progranulin (PGRN) can reduce NK cell cytotoxicity through reduction of NK cell expansion, granzyme B transcription, and NK cell-mediated lysis of target cells.
Thu Sep 05 00:00:00 EDT 2019
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Nature communications
Ramakrishnan SK,Zhang H,Ma X,Jung I,Schwartz AJ,Triner D,Devenport SN,Das NK,Xue X,Zeng MY,Hu Y,Mortensen RM,Greenson JK,Cascalho M,Wobus CE,Colacino JA,Nunez G,Rui L,Shah YM
11-0031 was used in Flow cytometry/Cell sorting to determine the role of Microfold cells in systemic inflammatory responses.
Fri Feb 08 00:00:00 EST 2019
Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells.
Frontiers in immunology
Zwick M,Ulas T,Cho YL,Ried C,Grosse L,Simon C,Bernhard C,Busch DH,Schultze JL,Buchholz VR,Stutte S,Brocker T
11-0031-82 was used in Flow Cytometry to suggest that Ppef2 is crucial to support survival of immature CD8+ DCs, while Ppef2 down-regulation during DC-maturation limits T cell responses.
Tue Oct 27 00:00:00 EDT 2020
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice.
Scientific reports
Pennig J,Scherrer P,Gissler MC,Anto-Michel N,Hoppe N,Füner L,Härdtner C,Stachon P,Wolf D,Hilgendorf I,Mullick A,Bode C,Zirlik A,Goldberg IJ,Willecke F
11-0031 was used in Flow cytometry/Cell sorting to determine whether glucose lowering by empagliflozin accelerates atherosclerosis regression in a mouse model.
Fri Nov 29 00:00:00 EST 2019
Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.
Immunity
Šestan M,Marinović S,Kavazović I,Cekinović Đ,Wueest S,Turk Wensveen T,Brizić I,Jonjić S,Konrad D,Wensveen FM,Polić B
11-0031 was used in Flow cytometry/Cell sorting to study how viral infection effects insulin resistance.
Tue Jul 17 00:00:00 EDT 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
11-0031 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.
Cell stem cell
Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J
11-0031-82 was used in Flow Cytometry to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.
Thu Mar 01 00:00:00 EST 2018
Redirecting TGF-β Signaling through the β-Catenin/Foxo Complex Prevents Kidney Fibrosis.
Journal of the American Society of Nephrology : JASN
Qiao X,Rao P,Zhang Y,Liu L,Pang M,Wang H,Hu M,Tian X,Zhang J,Zhao Y,Wang XM,Wang C,Yu H,Guo F,Cao Q,Wang Y,Wang YM,Zhang GY,Lee VW,Alexander SI,Zheng G,Harris DCH
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Thu Feb 01 00:00:00 EST 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moreira D,Adamus T,Zhao X,Su YL,Zhang Z,White SV,Swiderski P,Lu X,DePinho RA,Pal SK,Kortylewski M
11-0031 was used in Flow cytometry/Cell sorting to show a novel strategy combining STAT3 inhibition with Toll-like Receptor 9 (TLR9) stimulation to unleash immune response against prostate cancers regardless of the genetic background.
Sat Dec 01 00:00:00 EST 2018
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America
Mitchell S,Roy K,Zangle TA,Hoffmann A
Tue Mar 20 00:00:00 EDT 2018
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.
Glia
Villadiego J,Labrador-Garrido A,Franco JM,Leal-Lasarte M,De Genst EJ,Dobson CM,Pozo D,Toledo-Aral JJ,Roodveldt C
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in T-Cell Activation
Mon Jan 01 00:00:00 EST 2018
Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.
Development (Cambridge, England)
Solanki A,Yanez DC,Ross S,Lau CI,Papaioannou E,Li J,Saldaña JI,Crompton T
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Jan 31 00:00:00 EST 2018
On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation.
Drug delivery
Shahzad KA,Wan X,Zhang L,Pei W,Zhang A,Younis M,Wang W,Shen C
11-0031 was used in Flow cytometry/Cell sorting to examine the direct and antigen-specific modulation on T cells by nanoparticles and combined use of multiple regulatory molecules.
Thu Nov 01 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
11-0031 was used in Flow cytometry/Cell sorting to demonstrate a novel role for mechanistic target of rapamycin complex 1 in the regulation of bone marrow environments that support B-cell differentiation via regulating IL-7 expression.
Sun Apr 01 00:00:00 EDT 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in T-Cell Activation
Thu Feb 01 00:00:00 EST 2018
Human Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.
Infection and immunity
Gomes RS,Silva MVT,Dos Santos JC,van Linge C,Reis JM,Teixeira MM,Pinto SA,Dorta ML,Bai X,Chan ED,Dinarello CA,Oliveira MAP,Joosten LAB,Ribeiro-Dias F
11-0031 was used in Flow cytometry/Cell sorting to study the role of interleukin-32γ in potentiating the Th1/Th17 immune response during experimental visceral leishmaniasis.
Tue May 01 00:00:00 EDT 2018
Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer's disease mice.
Journal of neuroimmunology
Kiyota T,Machhi J,Lu Y,Dyavarshetty B,Nemati M,Yokoyama I,Mosley RL,Gendelman HE
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response.
Scientific reports
Rodríguez-Baena FJ,Redondo-García S,Peris-Torres C,Martino-Echarri E,Fernández-Rodríguez R,Plaza-Calonge MDC,Anderson P,Rodríguez-Manzaneque JC
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Aug 30 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.
Nature communications
Wunderlich CM,Ackermann PJ,Ostermann AL,Adams-Quack P,Vogt MC,Tran ML,Nikolajev A,Waisman A,Garbers C,Theurich S,Mauer J,Hövelmeyer N,Wunderlich FT
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunocytochemistry
Wed Apr 25 00:00:00 EDT 2018
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.
Nature communications
Wunderlich CM,Ackermann PJ,Ostermann AL,Adams-Quack P,Vogt MC,Tran ML,Nikolajev A,Waisman A,Garbers C,Theurich S,Mauer J,Hövelmeyer N,Wunderlich FT
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunocytochemistry
Wed Apr 25 00:00:00 EDT 2018
Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane.
BMC cell biology
Zhu H,Liu W,Fang H
11-0031 was used in Flow cytometry/Cell sorting to study the underlying mechanism by which blood-brain barrier disruption promotes postoperative cognitive dysfunction in the elderly population.
Sat Sep 29 00:00:00 EDT 2018
S1P Signalling Differentially Affects Migration of Peritoneal B Cell Populations In Vitro and Influences the Production of Intestinal IgA In Vivo.
International journal of molecular sciences
Kleinwort A,Lührs F,Heidecke CD,Lipp M,Schulze T
11-0031 was used in Flow cytometry/Cell sorting to study the function of S1P signalling in the third B cell lineage.
Mon Jan 29 00:00:00 EST 2018
Adipose tissue extrinsic factor: Obesity-induced inflammation and the role of the visceral lymph node.
Physiology & behavior
Magnuson AM,Fouts JK,Regan DP,Booth AD,Dow SW,Foster MT
11-0031-82 was used in Flow cytometry/Cell sorting to elucidate how the lymphatic system may contribute to the comorbidities associated with visceral adipose tissue accumulation.
Fri Jun 01 00:00:00 EDT 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
11-0031 was used in Flow cytometry/Cell sorting to identify the potential use of cidofovir in therapeutic strategies to kill tumour cells and influence the immune system to fight cancer.
Tue Apr 24 00:00:00 EDT 2018
Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.
Nature communications
Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H
11-0031 was used in Flow cytometry/Cell sorting to suggest that different lung antigen-presenting cells modulate lung cDC1-mediated eosinophil recruitment dynamically.
Mon Sep 24 00:00:00 EDT 2018
IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates.
mBio
Schager AE,Dominguez-Medina CC,Necchi F,Micoli F,Goh YS,Goodall M,Flores-Langarica A,Bobat S,Cook CNL,Arcuri M,Marini A,King LDW,Morris FC,Anderson G,Toellner KM,Henderson IR,López-Macías C,MacLennan CA,Cunningham AF
11-0031 was used in Flow cytometry/Cell sorting to study how antibody responses to bacterial antigens develop and how vaccines like generalised modules for membrane antigens can work and help prevent infection.
Tue Mar 06 00:00:00 EST 2018
CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages.
Cell discovery
Li D,Hu M,Liu Y,Ye P,Du P,Li CS,Cheng L,Liu P,Jiang J,Su L,Wang S,Zheng P,Liu Y
11-0031-82 was used in Flow cytometry/Cell sorting to show that targeted mutation of Cd24 dramatically increased HCC burden while reducing intrahepatic macrophages and DEN-induced hepatocyte apoptosis.
Thu Oct 01 00:00:00 EDT 2020
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis.
Nature communications
Silva MC,Davoli-Ferreira M,Medina TS,Sesti-Costa R,Silva GK,Lopes CD,Cardozo LE,Gava FN,Lyroni K,Dias FC,Frade AF,Baron M,Nakaya HI,Figueiredo F,Alves-Filho JC,Cunha FQ,Tsatsanis C,Chevillard C,Cunha-Neto E,Hirsch E,Silva JS,Cunha TM
11-0031 was used in Flow cytometry/Cell sorting to investigate the essential role of the canonical PI3Kγ signalling pathway in the control of Trypanosoma cruzi infection.
Tue Apr 17 00:00:00 EDT 2018
Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide.
Neoplasia (New York, N.Y.)
Pittala S,Krelin Y,Shoshan-Barmatz V
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Fri Jun 01 00:00:00 EDT 2018
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Cell
Kortlever RM,Sodir NM,Wilson CH,Burkhart DL,Pellegrinet L,Brown Swigart L,Littlewood TD,Evan GI
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Nov 30 00:00:00 EST 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
11-0031 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 EST 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that autoreactive T-cells and chronic fungal infection, fostered by inflammation and epithelial injury, promote esophageal squamous cell carcinoma development.
Wed Apr 12 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Circulation research
Yan X,Zhang H,Fan Q,Hu J,Tao R,Chen Q,Iwakura Y,Shen W,Lu L,Zhang Q,Zhang R
11-0031 was used in Flow cytometry/Cell sorting to determine whether Dectin-2 signalling is involved in the healing process and cardiac remodelling after myocardial infarction and to elucidate the underlying molecular mechanisms.
Fri Mar 31 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
PTEN drives Th17 cell differentiation by preventing IL-2 production.
The Journal of experimental medicine
Kim HS,Jang SW,Lee W,Kim K,Sohn H,Hwang SS,Lee GR
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Nov 06 00:00:00 EST 2017
Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy.
Brain : a journal of neurology
Laurent C,Dorothée G,Hunot S,Martin E,Monnet Y,Duchamp M,Dong Y,Légeron FP,Leboucher A,Burnouf S,Faivre E,Carvalho K,Caillierez R,Zommer N,Demeyer D,Jouy N,Sazdovitch V,Schraen-Maschke S,Delarasse C,Buée L,Blum D
11-0031 was used in Flow cytometry/Cell sorting to elucidate the contribution of brain immune cells in tau-driven pathophysiology in Alzheimer's.
Sun Jan 01 00:00:00 EST 2017
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.
EMBO molecular medicine
Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
11-0031 was used in Flow cytometry/Cell sorting to propose that Samd14-Enh and an ensemble of anemia-responsive enhancers are essential for erythrocyte regeneration in stress erythropoiesis.
Mon Aug 07 00:00:00 EDT 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that combining an oncolytic virus with tumor-targeting immune checkpoint modulators elicits potent in situ autologous cancer vaccination, resulting in an efficacious, tumor-specific, and long-lasting therapeutic effect.
Sat Jul 15 00:00:00 EDT 2017
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.
PLoS medicine
Xu J,Guardado J,Hoffman R,Xu H,Namas R,Vodovotz Y,Xu L,Ramadan M,Brown J,Turnquist HR,Billiar TR
11-0031 was used in Flow cytometry/Cell sorting to suggest that IL33 may initiate early detrimental type 2 immune responses after trauma through ILC2 regulation of neutrophil IL5 production.
Sat Jul 01 00:00:00 EDT 2017
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
11-0031 was used in Flow cytometry/Cell sorting to investigate whether secondary lymphatics within visceral adiposity contribute to disease risk.
Sun Oct 01 00:00:00 EDT 2017
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
Mon May 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
11-0031 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
11-0031 was used in Flow cytometry/Cell sorting to show that nonlymphoid compartments can serve as reservoirs for Th2 memory cells, and furthermore that innate effector function of Th2 memory cells is restricted to CD4⁺ memory T cells residing in the peritoneal cavity.
Wed Feb 01 00:00:00 EST 2017
T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice.
European journal of immunology
Akkaya M,Akkaya B,Sheehan PW,Miozzo P,Pena M,Qi CF,Manzella-Lapeira J,Bolland S,Pierce SK
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Wed Nov 01 00:00:00 EDT 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
11-0031 was used in Flow cytometry/Cell sorting to suggest that newly created lymphatic vessels in the cornea driven by HSV-1 infection are critical in the delivery of soluble viral antigen to the draining lymph node.
Sun Jan 01 00:00:00 EST 2017
Occludin Expression in Epidermal γδ T Cells in Response to Epidermal Stress Causes Them To Migrate into Draining Lymph Nodes.
Journal of immunology (Baltimore, Md. : 1950)
Saito T,Yano M,Ohki Y,Tomura M,Nakano N
11-0031-82 was used in Flow Cytometry to determine that activated γδ T cells expressed occludin and migrated into draining lymph nodes in an occludin-dependent manner.
Sat Jul 01 00:00:00 EDT 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer.
International journal of immunopathology and pharmacology
Ma N,Liu Q,Hou L,Wang Y,Liu Z
11-0031 was used in Flow cytometry/Cell sorting to study the mechanisms of granulocyte macrophage colony stimulating factor underlying colorectal cancer development.
Thu Jun 01 00:00:00 EDT 2017
Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland.
Journal of mammary gland biology and neoplasia
Dill R,Walker AM
11-0031 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in immune cell recruitment.
Wed Mar 01 00:00:00 EST 2017
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Scientific reports
Atkin-Smith GK,Paone S,Zanker DJ,Duan M,Phan TK,Chen W,Hulett MD,Poon IK
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jan 06 00:00:00 EST 2017
The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue.
Nature microbiology
Grau KR,Roth AN,Zhu S,Hernandez A,Colliou N,DiVita BB,Philip DT,Riffe C,Giasson B,Wallet SM,Mohamadzadeh M,Karst SM
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sat Apr 01 00:00:00 EDT 2017
Fractional Laser Releases Tumor-Associated Antigens in Poorly Immunogenic Tumor and Induces Systemic Immunity.
Scientific reports
Kawakubo M,Cunningham TJ,Demehri S,Manstein D
11-0031 was used in Flow cytometry/Cell sorting to assess the utility of ablative fractional photothermolysis for treating oncological indications.
Fri Oct 06 00:00:00 EDT 2017
Hepatic stroma-educated regulatory DCs suppress CD8+ T cell proliferation in mice.
Oncotarget
Wang Q,He H,Chen D,Wang C,Xu Y,Song W
11-0031 was used in Flow cytometry/Cell sorting to assess whether and how liver dendritic cells suppress CD8+ T cells.
Tue Nov 07 00:00:00 EST 2017
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.
Oncoimmunology
Kersten K,Coffelt SB,Hoogstraat M,Verstegen NJM,Vrijland K,Ciampricotti M,Doornebal CW,Hau CS,Wellenstein MD,Salvagno C,Doshi P,Lips EH,Wessels LFA,de Visser KE
11-0031 was used in Flow cytometry/Cell sorting to demonstrate mammary tumor-derived CCL2 can facilitate the breast cancer-induced pro-metastatic systemic inflammatory gamma delta T cell-IL17–neutrophil axis.
Sat Jan 29 00:00:00 EST 2022
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
11003182 was used in flow cytometry to test the effect of paeoniflorin in experimental autoimmune encephalomyelitis, an animal model for multiple sclerosis
Mon Feb 06 00:00:00 EST 2017
The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models.
Clinical and translational allergy
Vonk MM,Wagenaar L,Pieters RHH,Knippels LMJ,Willemsen LEM,Smit JJ,van Esch BCAM,Garssen J
11-0031 was used in Flow cytometry/Cell sorting to compare oral immunotherapy and subcutaneous immunotherapy models for cows milk and peanut allergy.
Fri Apr 08 00:00:00 EDT 2022
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
11-0031 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 EDT 2017
Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid.
PLoS neglected tropical diseases
Castiglioni P,Hartley MA,Rossi M,Prevel F,Desponds C,Utzschneider DT,Eren RO,Zangger H,Brunner L,Collin N,Zehn D,Kuhlmann FM,Beverley SM,Fasel N,Ronet C
11-0031 was used in Flow cytometry/Cell sorting to develop a novel anti-endosymbiotic vaccine strategy against Leishmaniavirus, with potential applications in other similar viral infections.
Sun Jan 01 00:00:00 EST 2017
Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response.
Scientific reports
Soukup K,Halfmann A,Dillinger B,Poyer F,Martin K,Blauensteiner B,Kauer M,Kuttke M,Schabbauer G,Dohnal AM
11-0031 was used in Flow cytometry/Cell sorting to suggest that MAPK-activated protein kinase 2 deletion leads to an expansion of stimulatory CD103+ dendritic cells, mounting a potent CD8+ T cell anti-tumour response in mice.
Mon Sep 18 00:00:00 EDT 2017
Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.
Scientific reports
Costa-Gouveia J,Pancani E,Jouny S,Machelart A,Delorme V,Salzano G,Iantomasi R,Piveteau C,Queval CJ,Song OR,Flipo M,Deprez B,Saint-André JP,Hureaux J,Majlessi L,Willand N,Baulard A,Brodin P,Gref R
11-0031 was used in Flow cytometry/Cell sorting to pave the way for a future use of pCD NPs for the pulmonary delivery of the [ETH:Booster] pair in TB chemotherapy.
Fri Jul 14 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Tue Oct 17 00:00:00 EDT 2017
γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice.
Journal of neuroinflammation
Zhang X,Rocha-Ferreira E,Li T,Vontell R,Jabin D,Hua S,Zhou K,Nazmi A,Albertsson AM,Sobotka K,Ek J,Thornton C,Hagberg H,Mallard C,Leavenworth JW,Zhu C,Wang X
11-0031 was used in Flow cytometry/Cell sorting to study the contribution of different T cell subsets to white matter injury and consequent behavioural changes.
Wed Dec 20 00:00:00 EST 2017
Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response.
PloS one
Kawakubo M,Demehri S,Manstein D
11-0031 was used in Immunocytochemistry to explore the utility of ablative fractional photothermolysis in treating oncological indications, including induction of local tumour regression and inducing anti-tumour immunity.
Fri Oct 13 00:00:00 EDT 2017
Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response.
PloS one
Kawakubo M,Demehri S,Manstein D
11-0031 was used in Immunocytochemistry to explore the utility of ablative fractional photothermolysis in treating oncological indications, including induction of local tumour regression and inducing anti-tumour immunity.
Fri Oct 13 00:00:00 EDT 2017
The cryo-thermal therapy eradicated melanoma in mice by eliciting CD4+ T-cell-mediated antitumor memory immune response.
Cell death & disease
He K,Liu P,Xu LX
11-0031 was used in Flow cytometry/Cell sorting to demonstrate the therapeutic efficacy in other aggressive tumor models and further investigate the mechanism of long-term survival induced.
Thu Mar 23 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice.
Circulation research
Viola JR,Lemnitzer P,Jansen Y,Csaba G,Winter C,Neideck C,Silvestre-Roig C,Dittmar G,Döring Y,Drechsler M,Weber C,Zimmer R,Cenac N,Soehnlein O
11-0031 was used in Flow cytometry/Cell sorting to present evidence for the imbalance between inflammatory and resolving lipid mediators during atheroprogression, suggesting a novel strategy for resolving arterial inflammation.
Fri Oct 14 00:00:00 EDT 2016
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis.
Autophagy
Lee HY,Kim J,Quan W,Lee JC,Kim MS,Kim SH,Bae JW,Hur KY,Lee MS
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
11-0031 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 EDT 2016
Treatment with Interleukin-7 Restores Host Defense against Pneumocystis in CD4+ T-Lymphocyte-Depleted Mice.
Infection and immunity
Ruan S,Samuelson DR,Assouline B,Morre M,Shellito JE
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Development of a diet-induced murine model of diabetes featuring cardinal metabolic and pathophysiological abnormalities of type 2 diabetes.
Biology open
Morris JL,Bridson TL,Alim MA,Rush CM,Rudd DM,Govan BL,Ketheesan N
11-0031 was used in Flow cytometry/Cell sorting to develop a novel murine model, based on an energy-dense diet, which closely simulates the development of type 2 diabetes.
Mon Aug 15 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
The dual role of NK cells in antitumor reactions triggered by ionizing radiation in combination with hyperthermia.
Oncoimmunology
Finkel P,Frey B,Mayer F,Bösl K,Werthmöller N,Mackensen A,Gaipl US,Ullrich E
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.
Nature communications
Xu Y,Zhao F,Qiu Q,Chen K,Wei J,Kong Q,Gao B,Melo-Cardenas J,Zhang B,Zhang J,Song J,Zhang DD,Zhang J,Fan Y,Li H,Fang D
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jul 15 00:00:00 EDT 2016
The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.
Nature communications
Xu Y,Zhao F,Qiu Q,Chen K,Wei J,Kong Q,Gao B,Melo-Cardenas J,Zhang B,Zhang J,Song J,Zhang DD,Zhang J,Fan Y,Li H,Fang D
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jul 15 00:00:00 EDT 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Fri Oct 21 00:00:00 EDT 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.
JCI insight
Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Thu Jul 21 00:00:00 EDT 2016
Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.
PloS one
Hrdinka M,Sudan K,Just S,Drobek A,Stepanek O,Schlüter D,Reinhold D,Jordan BA,Gintschel P,Schraven B,Kreutz MR
11-0031 was used in Flow cytometry/Cell sorting to show that Prr7 loss does not result in a major immune system defect in mice.
Wed Nov 20 00:00:00 EST 2019
Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae.
PLoS neglected tropical diseases
Pionnier N,Brotin E,Karadjian G,Hemon P,Gaudin-Nomé F,Vallarino-Lhermitte N,Nieguitsila A,Fercoq F,Aknin ML,Marin-Esteban V,Chollet-Martin S,Schlecht-Louf G,Bachelerie F,Martin C
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that neutrophils contribute to early anti-filarial host responses via oxidative burst, degranulation and NETosis.
Fri Apr 01 00:00:00 EDT 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
11-0031 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model.
Scientific reports
Bazett M,Bergeron ME,Haston CK
11-0031 was used in Flow cytometry/Cell sorting to reveal a potential intestinal microbiome influence on lung response in BALB/c Cftr(tm1UNC) mice.
Tue Jan 12 00:00:00 EST 2016
Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.
Nature medicine
Chimen M,McGettrick HM,Apta B,Kuravi SJ,Yates CM,Kennedy A,Odedra A,Alassiri M,Harrison M,Martin A,Barone F,Nayar S,Hitchcock JR,Cunningham AF,Raza K,Filer A,Copland DA,Dick AD,Robinson J,Kalia N,Walker LSK,Buckley CD,Nash GB,Narendran P,Rainger GE
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that exogenous PEPITEM reduces T cell recruitment into inflamed tissues in multiple animal models of autoimmune, inflammatory diseases.
Fri May 01 00:00:00 EDT 2015
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
Nature immunology
Basu R,Whitley SK,Bhaumik S,Zindl CL,Schoeb TR,Benveniste EN,Pear WS,Hatton RD,Weaver CT
11-0031 was used in Flow cytometry/Cell sorting to assess the ability of IL-1 to override retinoic acid-mediated expression of the transcription factor Foxp3 and induce protective TH17 cell responses.
Sun Mar 01 00:00:00 EST 2015
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.
The Journal of clinical investigation
Baek JH,Zeng R,Weinmann-Menke J,Valerius MT,Wada Y,Ajay AK,Colonna M,Kelley VR
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that IL-34-dependent mechanisms promote persistent ischemia-incited acute kidney injury that worsens subsequent chronic kidney disease.
Mon Aug 03 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
11-0031 was used in Flow cytometry/Cell sorting to illustrate a paradigm in which cis-elements in a locus differentially control stem and progenitor cell transitions.
Tue Sep 01 00:00:00 EDT 2015
Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway.
eLife
Kumari S,Depoil D,Martinelli R,Judokusumo E,Carmona G,Gertler FB,Kam LC,Carman CV,Burkhardt JK,Irvine DJ,Dustin ML
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in T-Cell Activation
Wed Mar 11 00:00:00 EDT 2015
Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway.
eLife
Kumari S,Depoil D,Martinelli R,Judokusumo E,Carmona G,Gertler FB,Kam LC,Carman CV,Burkhardt JK,Irvine DJ,Dustin ML
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in T-Cell Activation
Wed Mar 11 00:00:00 EDT 2015
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
11-0031 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Radjabova V,Mastroeni P,Skjødt K,Zaccone P,de Bono B,Goodall JC,Chilvers ER,Juss JK,Jones DC,Trowsdale J,Barrow AD
11-0031 was used in Flow cytometry/Cell sorting to identify a novel leukocyte receptor, TARM1, and investigate the mechanisms underlying its proinflammatory effects.
Thu Oct 01 00:00:00 EDT 2015
Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that Spred1, a negative regulator of the Ras-ERK pathway, plays an important role in the proliferation and apoptosis of ILC2s and in cytokine secretion from ILC2s.
Sat Aug 01 00:00:00 EDT 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity.
Infection and immunity
Shourian M,Flaczyk A,Angers I,Mindt BC,Fritz JH,Qureshi ST
11-0031 was used in Flow cytometry/Cell sorting to show that Cryptococcus neoformans infected lungs showed a significantly higher number of neutrophils, exudate macrophages, CD11b(+) dendritic cells, and CD4(+) cells in B6.CBA-Cnes2 than in C57BL/6 mice.
Tue Dec 01 00:00:00 EST 2015
Parasite Manipulation of the Invariant Chain and the Peptide Editor H2-DM Affects Major Histocompatibility Complex Class II Antigen Presentation during Toxoplasma gondii Infection.
Infection and immunity
Leroux LP,Nishi M,El-Hage S,Fox BA,Bzik DJ,Dzierszinski FS
11-0031 was used in Flow cytometry/Cell sorting to show that Toxoplasma gondii modulates the expression of key components of the MHC-II antigen presentation pathway in professional antigen-presenting cells.
Thu Oct 01 00:00:00 EDT 2015
Interferon-γ-Mediated Natural Killer Cell Activation by an Aqueous Panax ginseng Extract.
Evidence-based complementary and alternative medicine : eCAM
Takeda K,Okumura K
11-0031 was used in Flow cytometry/Cell sorting to examine the effects of P. ginseng extracts on the cytotoxic activity of NK cells.
Wed Dec 09 00:00:00 EST 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue May 24 00:00:00 EDT 2016
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.
BMC cancer
Gillgrass AE,Chew MV,Krneta T,Ashkar AA
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Thu Apr 16 00:00:00 EDT 2015
Loss of Gadkin Affects Dendritic Cell Migration In Vitro.
PloS one
Schachtner H,Weimershaus M,Stache V,Plewa N,Legler DF,Höpken UE,Maritzen T
11-0031 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which Gadkin and ARP2/3 regulate dendritic cell motility and migration.
Mon Jun 20 00:00:00 EDT 2016
Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus.
Nature communications
Yanagihara T,Sanematsu F,Sato T,Uruno T,Duan X,Tomino T,Harada Y,Watanabe M,Wang Y,Tanaka Y,Nakanishi Y,Suyama M,Yoshinori F
11-0031 was used in Flow cytometry/Cell sorting to study the regulation of Aire expression in medullary thymic epithelial cells.
Wed Nov 04 00:00:00 EST 2015
Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Nature communications
Stanic J,Carta M,Eberini I,Pelucchi S,Marcello E,Genazzani AA,Racca C,Mulle C,Di Luca M,Gardoni F
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Fri Dec 18 00:00:00 EST 2015
Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Nature communications
Stanic J,Carta M,Eberini I,Pelucchi S,Marcello E,Genazzani AA,Racca C,Mulle C,Di Luca M,Gardoni F
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Fri Dec 18 00:00:00 EST 2015
Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Nature communications
Stanic J,Carta M,Eberini I,Pelucchi S,Marcello E,Genazzani AA,Racca C,Mulle C,Di Luca M,Gardoni F
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Fri Dec 18 00:00:00 EST 2015
Structure-based programming of lymph-node targeting in molecular vaccines.
Nature
Liu H,Moynihan KD,Zheng Y,Szeto GL,Li AV,Huang B,Van Egeren DS,Park C,Irvine DJ
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Thu Mar 27 00:00:00 EDT 2014
CD4+ T cells promote the transition from hypertrophy to heart failure during chronic pressure overload.
Circulation
Laroumanie F,Douin-Echinard V,Pozzo J,Lairez O,Tortosa F,Vinel C,Delage C,Calise D,Dutaur M,Parini A,Pizzinat N
11-0031 was used in Flow cytometry/Cell sorting to investigate the involvement of T cells in the progression to heart failure using a transverse aortic constriction (TAC) model.
Tue May 27 00:00:00 EDT 2014
CD4+ T cells promote the transition from hypertrophy to heart failure during chronic pressure overload.
Circulation
Laroumanie F,Douin-Echinard V,Pozzo J,Lairez O,Tortosa F,Vinel C,Delage C,Calise D,Dutaur M,Parini A,Pizzinat N
11-0031 was used in Flow cytometry/Cell sorting to investigate the involvement of T cells in the progression to heart failure using a transverse aortic constriction (TAC) model.
Tue May 27 00:00:00 EDT 2014
An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment.
Blood
Gibbins JD,Ancelet LR,Weinkove R,Compton BJ,Painter GF,Petersen TR,Hermans IF
11-0031 was used in Flow cytometry/Cell sorting to investigate the efficacy of an intravenously administered vaccine consisting of irradiated leukemia cells loaded with α-GalCer.
Thu Nov 06 00:00:00 EST 2014
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.
Science translational medicine
Beale J,Jayaraman A,Jackson DJ,Macintyre JDR,Edwards MR,Walton RP,Zhu J,Man Ching Y,Shamji B,Edwards M,Westwick J,Cousins DJ,Yi Hwang Y,McKenzie A,Johnston SL,Bartlett NW
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion.
European journal of immunology
Larsen J,Dall M,Antvorskov JC,Weile C,Engkilde K,Josefsen K,Buschard K
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.
Journal of immunology (Baltimore, Md. : 1950)
Donnelly RP,Loftus RM,Keating SE,Liou KT,Biron CA,Gardiner CM,Finlay DK
11-0031 was used in Flow cytometry/Cell sorting to investigate whether mTORC1-controlled metabolism underpins normal natural killer cell proinflammatory functions.
Sat Nov 01 00:00:00 EDT 2014
CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
Journal of immunology (Baltimore, Md. : 1950)
Bignon A,Gaudin F,Hémon P,Tharinger H,Mayol K,Walzer T,Loetscher P,Peuchmaur M,Berrebi D,Balabanian K
11-0031 was used in Flow cytometry/Cell sorting to define a pivotal role for CCR4 in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of lupus-prone mice.
Sat Feb 01 00:00:00 EST 2014
Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Mercadante AC,Perobelli SM,Alves AP,Gonçalves-Silva T,Mello W,Gomes-Santos AC,Miyoshi A,Azevedo V,Faria AM,Bonomo A
11-0031 was used in Flow cytometry/Cell sorting to suggest that combined therapy is a promising strategy for prevention of GVHD with preservation of graft-versus-leukemia in allogenic HSCT.
Sat Feb 15 00:00:00 EST 2014
IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner.
Journal of immunology (Baltimore, Md. : 1950)
Alves BN,Tsui R,Almaden J,Shokhirev MN,Davis-Turak J,Fujimoto J,Birnbaum H,Ponomarenko J,Hoffmann A
11-0031 was used in Flow cytometry/Cell sorting to illustrate the importance of kinetic considerations in understanding the functional specificity of negative-feedback regulators.
Tue Apr 01 00:00:00 EDT 2014
An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.
Genes and immunity
Lafferty EI,Flaczyk A,Angers I,Homer R,d'Hennezel E,Malo D,Piccirillo CA,Vidal SM,Qureshi ST
11-0031 was used in Flow cytometry/Cell sorting to establish a role for Unc93b1 and endosomal TLRs in the activation of both myeloid and lymphoid cells during the innate immune response to influenza.
Fri Apr 10 00:00:00 EDT 2015
rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study.
Gene therapy
Rocca CJ,Ur SN,Harrison F,Cherqui S
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunofluorescence
Sun Jun 01 00:00:00 EDT 2014
Inhibition of eIF5A results in aberrant uterine natural killer cell function and embryo loss in mice.
American journal of reproductive immunology (New York, N.Y. : 1989)
Qin X,Liu X,Shan B,Shi L,Sharma S,Wu J,Lin Y
11-0031 was used in Flow cytometry/Cell sorting to investigate the effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of eukaryotic initiation factor 5A, on natural killer cells in vitro.
Sat Mar 01 00:00:00 EST 2014
Role of IL-17 and TGF-β in peritoneal adhesion formation after surgical trauma.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Wang G,Wu K,Li W,Zhao E,Shi L,Wang J,Shuai X,Cai K,Lu X,Tao K,Wang G
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Jun 30 00:00:00 EDT 2015
A method for high purity intestinal epithelial cell culture from adult human and murine tissues for the investigation of innate immune function.
Journal of immunological methods
Graves CL,Harden SW,LaPato M,Nelson M,Amador B,Sorenson H,Frazier CJ,Wallet SM
11-0031 was used in Flow cytometry/Cell sorting to demonstrate a novel culture method for more appropriate study of intestinal epithelial cells as innate immune effectors.
Mon Dec 01 00:00:00 EST 2014
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2015
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2015
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
11-0031 was used in Flow cytometry/Cell sorting to determine the impact of inhibitory NLR proteins in diseases shaped by adaptive immune responses.
Fri Feb 14 00:00:00 EST 2014
Mycobacterial membrane vesicles administered systemically in mice induce a protective immune response to surface compartments of Mycobacterium tuberculosis.
mBio
Prados-Rosales R,Carreño LJ,Batista-Gonzalez A,Baena A,Venkataswamy MM,Xu J,Yu X,Wallstrom G,Magee DM,LaBaer J,Achkar JM,Jacobs WR,Chan J,Porcelli SA,Casadevall A
Tue Sep 30 00:00:00 EDT 2014
Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
BMC biology
Reynolds C,Chong D,Raynsford E,Quigley K,Kelly D,Llewellyn-Hughes J,Altmann D,Boyton R
11-0031 was used in Flow cytometry/Cell sorting to study how the conformation of TCR alpha chain CDR3 favours different CD4 cytokine profiles.
Fri May 09 00:00:00 EDT 2014
Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.
mBio
Livermore J,Howard SJ,Sharp AD,Goodwin J,Gregson L,Felton T,Schwartz JA,Walker C,Moser B,Müller W,Harrison TS,Perfect JR,Hope WW
11-0031 was used in Flow cytometry/Cell sorting to investigate the efficacy of conventional and abbreviated regimens of dAmB for cryptococcal meningoencephalitis in murine and rabbit models.
Tue Jan 28 00:00:00 EST 2014
The use of anchored agonists of phagocytic receptors for cancer immunotherapy: B16-F10 murine melanoma model.
PloS one
Janotová T,Jalovecká M,Auerová M,Švecová I,Bruzlová P,Maierová V,Kumžáková Z,Cunátová Š,Vlčková Z,Caisová V,Rozsypalová P,Lukáčová K,Vácová N,Wachtlová M,Salát J,Lieskovská J,Kopecký J,Ženka J
11-0031 was used in Flow cytometry/Cell sorting to assess the anti-tumour potential of fusing phagocytic receptor agonists to cancer cells.
Thu Sep 18 00:00:00 EDT 2014
Cyclic GMP-AMP displays mucosal adjuvant activity in mice.
PloS one
Škrnjug I,Guzmán CA,Rueckert C
11-0031 was used in Flow cytometry/Cell sorting to explore the efficacy of cGAMP as a mucosal adjuvant in mice.
Fri Oct 09 00:00:00 EDT 2015
Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity.
Cell reports
Toso A,Revandkar A,Di Mitri D,Guccini I,Proietti M,Sarti M,Pinton S,Zhang J,Kalathur M,Civenni G,Jarrossay D,Montani E,Marini C,Garcia-Escudero R,Scanziani E,Grassi F,Pandolfi PP,Catapano CV,Alimonti A
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that immune surveillance of senescent tumour cells can be suppressed in specific genetic backgrounds but also evoked by pharmacological treatments.
Thu Oct 09 00:00:00 EDT 2014
γδT cells are prevalent in the proximal aorta and drive nascent atherosclerotic lesion progression and neutrophilia in hypercholesterolemic mice.
PloS one
Vu DM,Tai A,Tatro JB,Karas RH,Huber BT,Beasley D
11-0031 was used in Flow cytometry/Cell sorting to reveal a pathogenic role of γδT cells in early atherogenesis in ApoE KO mice, by mechanisms likely to involve their IL-17 production and induction of neutrophilia.
Tue Jun 16 00:00:00 EDT 2015
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.
The Journal of clinical investigation
Bonito AJ,Aloman C,Fiel MI,Danzl NM,Cha S,Weinstein EG,Jeong S,Choi Y,Walsh MC,Alexandropoulos K
11-0031 was used in Flow cytometry/Cell sorting to investigate the role of TRAF6 and medullary thymic epithelial cells (mETCs) in autoimmunity, showing that mETC depletion leads to autoimmune hepatitis.
Thu Aug 01 00:00:00 EDT 2013
Nanoparticle clearance is governed by Th1/Th2 immunity and strain background.
The Journal of clinical investigation
Jones SW,Roberts RA,Robbins GR,Perry JL,Kai MP,Chen K,Bo T,Napier ME,Ting JP,Desimone JM,Bear JE
11-0031 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in the clearance of particles from blood.
Mon Jul 01 00:00:00 EDT 2013
The Nlrp3 inflammasome regulates acute graft-versus-host disease.
The Journal of experimental medicine
Jankovic D,Ganesan J,Bscheider M,Stickel N,Weber FC,Guarda G,Follo M,Pfeifer D,Tardivel A,Ludigs K,Bouazzaoui A,Kerl K,Fischer JC,Haas T,Schmitt-Gräff A,Manoharan A,Müller L,Finke J,Martin SF,Gorka O,Peschel C,Ruland J,Idzko M,Duyster J,Holler E,French LE,Poeck H,Contassot E,Zeiser R
11-0031 was used in Flow cytometry/Cell sorting to study the establishment and role of the Nlrp3 inflammasome in acute graft-versus-host disease.
Mon Sep 23 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2013
Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice.
European journal of immunology
Pagán AJ,Peters NC,Debrabant A,Ribeiro-Gomes F,Pepper M,Karp CL,Jenkins MK,Sacks DL
11-0031 was used in Flow cytometry/Cell sorting to study parasite-specific primary CD4(+) T-cell responses to L. major in mice resistant to infection.
Fri Feb 01 00:00:00 EST 2013
High frequencies of activated B cells and T follicular helper cells are correlated with disease activity in patients with new-onset rheumatoid arthritis.
Clinical and experimental immunology
Wang J,Shan Y,Jiang Z,Feng J,Li C,Ma L,Jiang Y
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Human IL-2 mutein with higher antitumor efficacy than wild type IL-2.
Journal of immunology (Baltimore, Md. : 1950)
Carmenate T,Pacios A,Enamorado M,Moreno E,Garcia-Martínez K,Fuente D,León K
11-0031 was used in Flow cytometry/Cell sorting to characterise a human IL-2 mutant for used intreatment of melanoma and renal cell carcinoma, showing that mutant IL-2 has a higher antitumor efficacy and lower toxicity than wild type IL-2.
Sat Jun 15 00:00:00 EDT 2013
Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.
Transplantation
Shimamura M,Seleme MC,Guo L,Saunders U,Schoeb TR,George JF,Britt WJ
11-0031 was used in Flow cytometry/Cell sorting to examine the lasting effect of Ganciclovir treatment on renal allografts after the discontinuation of prophylaxis.
Tue Jan 15 00:00:00 EST 2013
Uterine natural killer cells severely decrease in number at gestation day 6 in mice.
Biology of reproduction
Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T
11-0031 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.
Tue Oct 01 00:00:00 EDT 2013
Identification of gingipain-specific I-A(b) -restricted CD4+ T cells following mucosal colonization with Porphyromonas gingivalis in C57BL/6 mice.
Molecular oral microbiology
Bittner-Eddy PD,Fischer LA,Costalonga M
11-0031 was used in Flow cytometry/Cell sorting to investigate whether MHC class II I-A(b) -binding peptides are presented to CD4(+) T cells during P. gingivalis oral colonisation.
Sun Dec 01 00:00:00 EST 2013
Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer Cell Growth in Mice.
Journal of cancer science & therapy
Zheng D,Chen H,Bartee MY,Williams J,Davids JA,Lomas DA,McFadden G,Lucas AR
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Aug 19 00:00:00 EDT 2013
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
11-0031 was used in Flow cytometry/Cell sorting to determine that Nod2 is functional in murine CD4(+) T cells, but unnecessary for the regulation of colitis.
Thu Jul 31 00:00:00 EDT 2014
Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency.
PloS one
Pioli PD,Dahlem TJ,Weis JJ,Weis JH
11-0031 was used in Flow cytometry/Cell sorting to investigate the function of Snai3, demonstrating its partial functional redundancy.
Wed Feb 19 00:00:00 EST 2014
The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function.
American journal of clinical and experimental immunology
Noonan T,Lukas S,Peet GW,Pelletier J,Panzenbeck M,Hanidu A,Mazurek S,Wasti R,Rybina I,Roma T,Kronkaitis A,Shoultz A,Souza D,Jiang H,Nabozny G,Modis LK
11-0031 was used in Flow cytometry/Cell sorting to assess the relative contribution of the features of vascular adhesion protein-1 to its function.
Thu Jul 25 00:00:00 EDT 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
11-0031 was used in Flow cytometry/Cell sorting to reveal the specificity of E2F8 in mediating Rb function in erythropoiesis.
Thu May 10 00:00:00 EDT 2012
Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants.
International journal of cancer
Kaluza KM,Thompson JM,Kottke TJ,Flynn Gilmer HC,Knutson DL,Vile RG
11-0031 was used in Flow cytometry/Cell sorting to study the mechanisms by which adoptive T cell therapy promotes the emergence of genomically altered tumour escape variants.
Wed Aug 15 00:00:00 EDT 2012
Pulmonary T cell activation in response to chronic particulate air pollution.
American journal of physiology. Lung cellular and molecular physiology
Deiuliis JA,Kampfrath T,Zhong J,Oghumu S,Maiseyeu A,Chen LC,Sun Q,Satoskar AR,Rajagopalan S
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Feb 15 00:00:00 EST 2012
Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells.
Journal of immunology (Baltimore, Md. : 1950)
Richmond JM,Lee J,Green DS,Kornfeld H,Cruikshank WW
11-0031 was used in Flow cytometry/Cell sorting to examine the ability of ManLAM to desensitize T cells to other chemoattractants during mycobacterial infection.
Sat Dec 15 00:00:00 EST 2012
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Journal of immunology (Baltimore, Md. : 1950)
Gowda NM,Wu X,Gowda DC
11-0031 was used in Flow cytometry/Cell sorting to investigate TLR9 and MyD88 regulation of pro/anti-inflammatory cytokines in mice infected with Plasmodium yoelii.
Tue May 15 00:00:00 EDT 2012
Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice.
Journal of immunology (Baltimore, Md. : 1950)
Iwata Y,Boström EA,Menke J,Rabacal WA,Morel L,Wada T,Kelley VR
11-0031 was used in Flow cytometry/Cell sorting to elucidate the macrophage-associated effects of CSF-1 expression by tubular epithelial cells during kidney inflammation.
Tue May 01 00:00:00 EDT 2012
The development of colitogenic CD4(+) T cells is regulated by IL-7 in collaboration with NK cell function in a murine model of colitis.
Journal of immunology (Baltimore, Md. : 1950)
Yamaji O,Nagaishi T,Totsuka T,Onizawa M,Suzuki M,Tsuge N,Hasegawa A,Okamoto R,Tsuchiya K,Nakamura T,Arase H,Kanai T,Watanabe M
11-0031 was used in Flow cytometry/Cell sorting to suggest that NK cells suppress colitis severity in T cell-reconstituted RAG(-/-) and IL-7(-/-)RAG(-/-) recipient mice.
Thu Mar 15 00:00:00 EDT 2012
CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs.
Journal of immunology (Baltimore, Md. : 1950)
Pagán AJ,Pepper M,Chu HH,Green JM,Jenkins MK
11-0031 was used in Flow cytometry/Cell sorting to track polyclonal peptide:MHCII-specific CD4+ T cells in vivo, in mice with mutations in two sites within the cytoplasmic tail of CD28.
Sat Sep 15 00:00:00 EDT 2012
A critical role for Rictor in T lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Tang F,Wu Q,Ikenoue T,Guan KL,Liu Y,Zheng P
11-0031 was used in Flow cytometry/Cell sorting to investigate the signalling pathway required for T lymphopoiesis, showing a critical role for Rictor.
Wed Aug 15 00:00:00 EDT 2012
Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice.
American journal of physiology. Gastrointestinal and liver physiology
Ernst PB,Erickson LD,Loo WM,Scott KG,Wiznerowicz EB,Brown CC,Torres-Velez FJ,Alam MS,Black SG,McDuffie M,Feldman SH,Wallace JL,McKnight GW,Padol IT,Hunt RH,Tung KS
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sun Jan 01 00:00:00 EST 2012
Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice.
American journal of physiology. Gastrointestinal and liver physiology
Ernst PB,Erickson LD,Loo WM,Scott KG,Wiznerowicz EB,Brown CC,Torres-Velez FJ,Alam MS,Black SG,McDuffie M,Feldman SH,Wallace JL,McKnight GW,Padol IT,Hunt RH,Tung KS
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Immunohistochemistry
Sun Jan 01 00:00:00 EST 2012
Adoptive transfer of cytotoxic T lymphocytes targeting two different antigens limits antigen loss and tumor escape.
Human gene therapy
Kaluza KM,Kottke T,Diaz RM,Rommelfanger D,Thompson J,Vile R
11-0031 was used in Flow cytometry/Cell sorting to study whether cytotoxic T lymphocytes targeting multiple antigens are more effective for preventing tumour escape than those targeting a single antigen.
Mon Oct 01 00:00:00 EDT 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect.
The journal of gene medicine
Fotin-Mleczek M,Zanzinger K,Heidenreich R,Lorenz C,Thess A,Duchardt KM,Kallen KJ
11-0031 was used in Flow cytometry/Cell sorting to study the effects of CureVac's mRNA vaccines in prostate cancer and non-small cell lung carcinoma patients.
Fri Jun 01 00:00:00 EDT 2012
Species-specific activity of glycolipid ligands for invariant NKT cells.
Chembiochem : a European journal of chemical biology
Dangerfield EM,Cheng JM,Knight DA,Weinkove R,Dunbar PR,Hermans IF,Timmer MS,Stocker BL
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jun 18 00:00:00 EDT 2012
Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy.
PloS one
Golias J,Schwarzer M,Wallner M,Kverka M,Kozakova H,Srutkova D,Klimesova K,Sotkovsky P,Palova-Jelinkova L,Ferreira F,Tuckova L
11-0031 was used in Flow cytometry/Cell sorting to investigate how thermal processing influences the ability of ovalbumin to induce allergic symptoms in a mouse model.
Mon Dec 17 00:00:00 EST 2012
Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF.
The Journal of biological chemistry
Badeaux AI,Yang Y,Cardenas K,Vemulapalli V,Chen K,Kusewitt D,Richie E,Li W,Bedford MT
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Jan 02 00:00:00 EST 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.
Journal of the American Heart Association
Yan X,Shichita T,Katsumata Y,Matsuhashi T,Ito H,Ito K,Anzai A,Endo J,Tamura Y,Kimura K,Fujita J,Shinmura K,Shen W,Yoshimura A,Fukuda K,Sano M
11-0031 was used in Flow cytometry/Cell sorting to explore potential immune pathways involved in left ventricular remodelling as possible preventative therapeutic options.
Mon Oct 01 00:00:00 EDT 2012
Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice.
Gastroenterology
Aoki N,Kido M,Iwamoto S,Nishiura H,Maruoka R,Tanaka J,Watanabe T,Tanaka Y,Okazaki T,Chiba T,Watanabe N
11-0031 was used in Flow cytometry/Cell sorting to identify induction sites, responsible T-cell subsets, and key molecules for induction of autoimmune hepatitis.
Fri Apr 01 00:00:00 EDT 2011
Interferon-γ production by neutrophils during bacterial pneumonia in mice.
American journal of respiratory and critical care medicine
Yamada M,Gomez JC,Chugh PE,Lowell CA,Dinauer MC,Dittmer DP,Doerschuk CM
11-0031 was used in Flow cytometry/Cell sorting to reveal that neutrophils produce IFN-γ early in the inflammatory response during pneumonia induced by some bacteria, but not others.
Sun May 15 00:00:00 EDT 2011
Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival.
Blood
Reijmers RM,Groen RW,Kuil A,Weijer K,Kimberley FC,Medema JP,van Kuppevelt TH,Li JP,Spaargaren M,Pals ST
11-0031 was used in Flow cytometry/Cell sorting to identify heparan sulfate proteoglycans as novel players in B-cell maturation and differentiation and suggest that heparan sulfate conformation is crucial for recruitment of factors that control plasma cell survival.
Thu Jun 09 00:00:00 EDT 2011
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice.
The Journal of allergy and clinical immunology
Arias K,Chu DK,Flader K,Botelho F,Walker T,Arias N,Humbles AA,Coyle AJ,Oettgen HC,Chang HD,Van Rooijen N,Waserman S,Jordana M
11-0031 was used in Flow cytometry/Cell sorting to investigate the relative contribution of immunoglobulin-dependent effector pathways to anaphylactic responses to food.
Wed Jun 01 00:00:00 EDT 2011
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor.
PLoS pathogens
Perry ST,Buck MD,Lada SM,Schindler C,Shresta S
11-0031 was used in Flow cytometry/Cell sorting to determine the molecular basis of the STAT1-independent pathway that confers resistance to Dengue virus-induced disease in STAT1-deficient mice.
Tue Feb 01 00:00:00 EST 2011
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.
Immunology
Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL
11-0031 was used in Flow cytometry/Cell sorting to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.
Tue Feb 01 00:00:00 EST 2011
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Barao I,Alvarez M,Redelman D,Weiss JM,Ortaldo JR,Wiltrout RH,Murphy WJ
11-0031 was used in Flow cytometry/Cell sorting to highlight cytokine gene transfer-based methods as a potential platform for natural killer cell recovery after bone marrow transplantation in mice.
Thu Dec 01 00:00:00 EST 2011
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
11-0031 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.
Journal of immunology (Baltimore, Md. : 1950)
Brincks EL,Gurung P,Langlois RA,Hemann EA,Legge KL,Griffith TS
11-0031 was used in Flow cytometry/Cell sorting to study how TRAIL affects the T cell response and ultimately influences the outcome of viral infection.
Tue Nov 01 00:00:00 EDT 2011
Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody.
Investigative ophthalmology & visual science
Ishida W,Fukuda K,Sakamoto S,Koyama N,Koyanagi A,Yagita H,Fukushima A
11-0031 was used in Flow cytometry/Cell sorting to investigate the involvement of δ-like ligand (Dll)4 in the development of experimental autoimmune uveoretinitis in B10.RIII mice.
Mon Oct 17 00:00:00 EDT 2011
Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice.
Biology of reproduction
Meng J,Greenlee AR,Taub CJ,Braun RE
11-0031 was used in Flow cytometry/Cell sorting to show that Sertoli cell-specific Ar ablation leads to defective tight junction ultrastructure and elevated IgG in mouse testes.
Mon Aug 01 00:00:00 EDT 2011
Prevention of NKT cell activation accelerates cutaneous wound closure and alters local inflammatory signals.
The Journal of surgical research
Schneider DF,Palmer JL,Tulley JM,Kovacs EJ,Gamelli RL,Faunce DE
11-0031 was used in Flow cytometry/Cell sorting to explore the effects of purposefully inhibiting natural killer T cell activation on the response to injury.
Tue Nov 01 00:00:00 EDT 2011
CD8 T-cell activation in mice injected with a plasmid DNA vaccine encoding AMA-1 of the reemerging Korean Plasmodium vivax.
The Korean journal of parasitology
Kim HJ,Jung BK,Lee JJ,Pyo KH,Kim TY,Choi BI,Kim TW,Hisaeda H,Himeno K,Shin EH,Chai JY
11-0031 was used in Flow cytometry/Cell sorting to study the cellular immunogenicity of a plasmid DNA vaccine - encoding AMA-1 of Plasmodium vivax - to mice.
Tue Mar 01 00:00:00 EST 2011
Low CD4/CD8 T-cell ratio associated with inflammatory arthropathy in human T-cell leukemia virus type I Tax transgenic mice.
PloS one
Ohsugi T,Kumasaka T
11-0031 was used in Flow cytometry/Cell sorting to identify the primary T-cell subsets involved in the development of arthropathy in Tax transgenic mice.
Fri Apr 01 00:00:00 EDT 2011
Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia.
Blood
Giuriato S,Foisseau M,Dejean E,Felsher DW,Al Saati T,Demur C,Ragab A,Kruczynski A,Schiff C,Delsol G,Meggetto F
11-0031 was used in Flow cytometry/Cell sorting to develop conditional mouse models for anaplastic lymphoma kinase-induced lymphomagenesis.
Thu May 20 00:00:00 EDT 2010
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Obesity (Silver Spring, Md.)
Strissel KJ,DeFuria J,Shaul ME,Bennett G,Greenberg AS,Obin MS
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2010
Interleukin-15 is critical in the pathogenesis of influenza a virus-induced acute lung injury.
Journal of virology
Nakamura R,Maeda N,Shibata K,Yamada H,Kase T,Yoshikai Y
11-0031 was used in Flow cytometry/Cell sorting to determine why interleukin-15 knockout mice exhibit reduced mortality after infection with influenza virus A.
Tue Jun 01 00:00:00 EDT 2010
VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model.
Immunology and cell biology
Chen L,Lin SX,Amin S,Overbergh L,Maggiolino G,Chan LS
11-0031 was used in Flow cytometry/Cell sorting to investigate the functions of ICAM-1 and VCAM-1 in a keratin-14 IL-4-Tg mouse model of atopic dermatitis.
Fri Jun 11 00:00:00 EDT 2010
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Journal of immunology (Baltimore, Md. : 1950)
Ito H,Hoshi M,Ohtaki H,Taguchi A,Ando K,Ishikawa T,Osawa Y,Hara A,Moriwaki H,Saito K,Seishima M
11-0031 was used in Flow cytometry/Cell sorting to study the immunological effects of IDO in α-galactosylceramide (α-GalCer)-induced hepatitis.
Fri Oct 15 00:00:00 EDT 2010
Resistance to dengue virus infection in mice is potentiated by CXCL10 and is independent of CXCL10-mediated leukocyte recruitment.
Journal of immunology (Baltimore, Md. : 1950)
Ip PP,Liao F
11-0031 was used in Flow cytometry/Cell sorting to study how CXCL10(-/-) mice are more susceptible than wild-type mice to dengue virus infection.
Sat May 15 00:00:00 EDT 2010
BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Smith IA,Knezevic BR,Ammann JU,Rhodes DA,Aw D,Palmer DB,Mather IH,Trowsdale J
11-0031 was used in Flow cytometry/Cell sorting to confirm a coinhibitory role for mouse BTN1A1.
Thu Apr 01 00:00:00 EDT 2010
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
11-0031 was used in Flow cytometry/Cell sorting to show the dendritic cell response to T.gondii alters levels of CD8+ T cells which ultimately determine the outcome of infection.
Sun Aug 01 00:00:00 EDT 2010
Efficient isolation of mouse liver NKT cells by perfusion.
PloS one
Fang X,Du P,Liu Y,Tang J
11-0031 was used in Flow cytometry/Cell sorting to develop a simple method to isolate NKT cells using perfusion, with similar yield to the traditional methods.
Wed Apr 21 00:00:00 EDT 2010
Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential.
Cell stem cell
Benveniste P,Frelin C,Janmohamed S,Barbara M,Herrington R,Hyam D,Iscove NN
11-0031 was used in Flow cytometry/Cell sorting to investigate the presence of "intermediate-term" multipotent hematopoietic stem cells, revealing that these cells are able to sustain clones of differentiating cells for only 4-6 weeks.
Fri Jan 08 00:00:00 EST 2010
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine.
Gastroenterology
Shang L,Thirunarayanan N,Viejo-Borbolla A,Martin AP,Bogunovic M,Marchesi F,Unkeless JC,Ho Y,Furtado GC,Alcami A,Merad M,Mayer L,Lira SA
11-0031 was used in Flow cytometry/Cell sorting to study the importance of the chemokine binding protein M3 in enabling distribution of leukocytes throughout the intestine.
Tue Sep 01 00:00:00 EDT 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
11-0031 was used in Flow cytometry/Cell sorting to detect epitope-specific T cells from the peripheral lymphoid organs of a mouse using the adoptive transfer of TCR transgenic T cells with a defined epitope specificity into histocompatible mice.
Tue Jun 30 00:00:00 EDT 2009
4-1BB functions as a survival factor in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Choi BK,Kim YH,Kwon PM,Lee SC,Kang SW,Kim MS,Lee MJ,Kwon BS
11-0031 was used in Immunofluorescence on frozen tissues to investigate the function of CD137 on dendritic cells, showing that it functions as a survival factor.
Wed Apr 01 00:00:00 EDT 2009
NKG2A inhibits invariant NKT cell activation in hepatic injury.
Journal of immunology (Baltimore, Md. : 1950)
Kawamura T,Takeda K,Kaneda H,Matsumoto H,Hayakawa Y,Raulet DH,Ikarashi Y,Kronenberg M,Yagita H,Kinoshita K,Abo T,Okumura K,Smyth MJ
11-0031 was used in Flow cytometry/Cell sorting to investigate the role of NK cell receptors in iNKT cell activation, showing that NKG2A-mediated signalling negatively regulated iNKT activation and hepatic injury.
Thu Jan 01 00:00:00 EST 2009
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
International immunology
Siegemund S,Schütze N,Schulz S,Wolk K,Nasilowska K,Straubinger RK,Sabat R,Alber G
11-0031 was used in Flow cytometry/Cell sorting to study whether IL-22 and IL-17A production is initiated early in response to S. Enteritidis, showing that early production of IL-22 was dependent on IL-23, however IL-17A was only partially IL-23-dependent.
Fri May 01 00:00:00 EDT 2009
Nylon wool purification alters the activation of T cells.
Molecular immunology
Wohler JE,Barnum SR
11-0031 was used in Flow cytometry/Cell sorting to examine the effects of nylon wool purification on T cell proliferation, activation marker expression and cytokine production.
Sun Feb 01 00:00:00 EST 2009
Deletion of both the C3a and C5a receptors fails to protect against experimental autoimmune encephalomyelitis.
Neuroscience letters
Ramos TN,Wohler JE,Barnum SR
11-0031 was used in Flow cytometry/Cell sorting to demonstrate the delayed onset of experimental autoimmune encephalomyelitis but no attenuation of disease severity in C3aR/C5aR double knockout mice.
Thu Dec 31 00:00:00 EST 2009
Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.
PloS one
Dace DS,Khan AA,Stark JL,Kelly J,Cross AH,Apte RS
11-0031 was used in Flow cytometry/Cell sorting to investigate the conditions contributing to the development of CIDP and related conditions.
Tue Sep 22 00:00:00 EDT 2009
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
European journal of immunology
White AJ,Withers DR,Parnell SM,Scott HS,Finke D,Lane PJ,Jenkinson EJ,Anderson G
11-0031 was used in Flow cytometry/Cell sorting to analyse the cellular and molecular requirements for the initial appearance of Aire+ medullary thymic epithelial cells in the embryonic thymus, in addition to their persistence in the adult thymus.
Tue Apr 01 00:00:00 EDT 2008
Synergistic antitumor effects of CpG oligodeoxynucleotide and STAT3 inhibitory agent JSI-124 in a mouse melanoma tumor model.
Immunology and cell biology
Molavi O,Ma Z,Hamdy S,Lai R,Lavasanifar A,Samuel J
11-0031 was used in Flow cytometry/Cell sorting to provide the proof-of-principle for combining CpG and JSI-124 to enhance anti-tumour immune responses.
Mon Oct 20 00:00:00 EDT 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-0031 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-0031 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.
PloS one
Cheng N,van de Wetering CI,Knudson CM
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2008
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
11-0031-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection.
Journal of virology
Ohno S,Ono N,Seki F,Takeda M,Kura S,Tsuzuki T,Yanagi Y
11-0031 was used in Flow cytometry/Cell sorting to investigate the effects on measles infection after replacement of the V domain of mouse SLAM with human SLAM.
Thu Feb 01 00:00:00 EST 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using CD3e monoclonal antibody (Product # 11-0031-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Tumor growth impedes natural-killer-cell maturation in the bone marrow.
Blood
Richards JO,Chang X,Blaser BW,Caligiuri MA,Zheng P,Liu Y
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that tumour growth can impede functional maturation of NK cells, most likely by interrupting the requisite IL-15 signalling pathway.
Sat Jul 01 00:00:00 EDT 2006
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma.
International journal of cancer
Geng H,Zhang GM,Xiao H,Yuan Y,Li D,Zhang H,Qiu H,He YF,Feng ZH
Thu Jun 01 00:00:00 EDT 2006
Cytosolic entry controls CD8+-T-cell potency during bacterial infection.
Infection and immunity
Bahjat KS,Liu W,Lemmens EE,Schoenberger SP,Portnoy DA,Dubensky TW,Brockstedt DG
11-0031 was used in Flow cytometry/Cell sorting to investigate microbial invasion of the cytosol as a key factor in inducing CD8+- T cell-mediated protection against L.monocytogenes.
Wed Nov 01 00:00:00 EST 2006
Mast cells enhance T cell activation: Importance of mast cell-derived TNF.
Proceedings of the National Academy of Sciences of the United States of America
Nakae S,Suto H,Kakurai M,Sedgwick JD,Tsai M,Galli SJ
11-0031 was used in Functional assays to investigate the mechanisms by which mast cells influence T cells in T cell-mediated disorders, showing that they enhance activation.
Tue May 03 00:00:00 EDT 2005
Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Krieg C,Han P,Stone R,Goularte OD,Kaye J
Tue Nov 15 00:00:00 EST 2005
Mac1 positive cells are required for enhancement of splenocytes proliferation caused by bisphenol a.
Bioscience, biotechnology, and biochemistry
Goto M,Ono H,Takano-Ishikawa Y,Shinmoto H,Yoshida M
11-0031 was used in Flow cytometry/Cell sorting to demonstrate that bisphenol A upregulates the proliferation of murine splenocytes stimulated with Concanavalin A.
Thu Jan 01 00:00:00 EST 2004
